Prurigo nodularis(PN)is a chronic pruritic inflammatory skin disease characterized by hyperkeratotic papules and nodules symmetrically distributed on the back and extensor surfaces of the extremities,accompanied by se...Prurigo nodularis(PN)is a chronic pruritic inflammatory skin disease characterized by hyperkeratotic papules and nodules symmetrically distributed on the back and extensor surfaces of the extremities,accompanied by severe pruritus.PN has a serious impact on quality of life.[1–3]PN is a complex and difficult-to-treat condition.There is a lack of unified understanding of its diagnosis and treatment specifications,and the means approved for treating PN are limited;thus,clinicians mostly use empirical therapies.展开更多
基金supported by a grant from the National Key Research and Development Programme of China(No.2023YFC2508200)
文摘Prurigo nodularis(PN)is a chronic pruritic inflammatory skin disease characterized by hyperkeratotic papules and nodules symmetrically distributed on the back and extensor surfaces of the extremities,accompanied by severe pruritus.PN has a serious impact on quality of life.[1–3]PN is a complex and difficult-to-treat condition.There is a lack of unified understanding of its diagnosis and treatment specifications,and the means approved for treating PN are limited;thus,clinicians mostly use empirical therapies.