The Chinese express delivery industry processes nearly 110 billion items in 2022,averaging an annual growth rate of 200%.Among the various types of sorting systems used for handling express items,cross-belt sorting sy...The Chinese express delivery industry processes nearly 110 billion items in 2022,averaging an annual growth rate of 200%.Among the various types of sorting systems used for handling express items,cross-belt sorting systems stand out as the most crucial.However,despite their high degree of automation,the workload for operators has intensified owing to the surging volume of express items.In the era of Industry 5.0,it is imperative to adopt new technologies that not only enhance worker welfare but also improve the efficiency of cross-belt systems.Striking a balance between efficiency in handling express items and operator well-being is challenging.Digital twin technology offers a promising solution in this respect.A realization method of a human-machine integrated digital twin is proposed in this study,enabling the interaction of biological human bodies,virtual human bodies,virtual equipment,and logistics equipment in a closed loop,thus setting an operating framework.Key technologies in the proposed framework include a collection of heterogeneous data from multiple sources,construction of the relationship between operator fatigue and operation efficiency based on physiological measurements,virtual model construction,and an online optimization module based on real-time simulation.The feasibility of the proposed method was verified in an express distribution center.展开更多
近年来,综合能源系统作为一种以多种能源形态和设备相互交互的能源系统方案得到了广泛应用和研究.然而,在面对动态复杂的多能源系统时,传统的优化调度方法往往无法满足其实时性和精准度需求.因此,本文设计了一种软深度确定性策略梯度(So...近年来,综合能源系统作为一种以多种能源形态和设备相互交互的能源系统方案得到了广泛应用和研究.然而,在面对动态复杂的多能源系统时,传统的优化调度方法往往无法满足其实时性和精准度需求.因此,本文设计了一种软深度确定性策略梯度(Soft Deep Deterministic Policy Gradient,Soft-DDPG)算法驱动的综合能源系统优化调度方法,以最小化调度周期内系统总运行成本为目标,建立设备运行综合能效评估模型,再采用Soft-DDPG算法对每个能源设备的能效调度动作进行优化控制.Soft-DDPG算法将softmax算子引入到动作值函数的计算中,有效降低了Q值高估问题.与此同时,该算法在动作选择策略中加入了随机噪声,提高了算法的学习效率.实验结果显示,本文所提出的方法解决了综合能源系统能效调度实时性差、精准度低的瓶颈问题,实现了系统的高效灵活调度,降低了系统的总运行成本.展开更多
4D printed smart materials is mostly relying on thermal stimulation to actuate,limiting their widely application requiring precise and localized control of the deformations.Most existing strategies for achieving local...4D printed smart materials is mostly relying on thermal stimulation to actuate,limiting their widely application requiring precise and localized control of the deformations.Most existing strategies for achieving localized control rely on hetero-geneous material systems and structural design,thereby increasing design and manufacturing complexity.Here,we endow localized electrothermal,actuation,and sensing properties in electrically-driven soft actuator through parameter-encoded 4D printing.We analyzed the effects of printing parameters on shape memory properties and conductivity,and then explored the multi-directional sensing performance of the 4D printed composites.We demonstrated an integrated actuator-sensor device capable of both shape recovery and perceiving its own position and obstacles simultaneously.Moreover,it can adjust its sensing characteristics through temporary shape programming to adapt to different application scenarios.This study achieves integrated and localized actuation-sensing without the need for multi-material systems and intricate structural designs,offering an efficient solution for the intelligent and lightweight design in the fields of soft robotics,biomedical applications,and aerospace.展开更多
The Regional Integrated Energy System(RIES)has brought new modes of development,utilization,conversion,storage of energy.The introduction of Soft Open Point(SOP)and the application of Power to Gas(P2G)technology will ...The Regional Integrated Energy System(RIES)has brought new modes of development,utilization,conversion,storage of energy.The introduction of Soft Open Point(SOP)and the application of Power to Gas(P2G)technology will greatly deepen the coupling of the electricity-gas integrated energy system,improve the flexibility and safety of the operation of the power system,and bring a deal of benefits to the power system.On this background,an optimal dispatch model of RIES combined cold,heat,gas and electricity with SOP is proposed.Firstly,RIES architecture with SOP and P2G is designed and its mathematical model also is built.Secondly,on the basis of considering the optimal scheduling of combined cold,heat,gas and electricity,the optimal scheduling model for RIES was established.After that,the original model is transformed into a mixed-integer second-order cone programming model by using linearization and second-order cone relaxation techniques,and the CPLEX solver is invoked to solve the optimization problem.Finally,the modified IEEE 33-bus systemis used to analyze the benefits of SOP,P2G technology and lithium bromide absorption chillers in reducing systemnetwork loss and cost,as well as improving the system’s ability to absorb wind and solar and operating safety.展开更多
Soft(flexible and stretchable) biosensors have great potential in real-time and continuous health monitoring of various physiological factors, mainly due to their better conformability to soft human tissues and organs...Soft(flexible and stretchable) biosensors have great potential in real-time and continuous health monitoring of various physiological factors, mainly due to their better conformability to soft human tissues and organs, which maximizes data fidelity and minimizes biological interference.Most of the early soft sensors focused on sensing physical signals. Recently, it is becoming a trend that novel soft sensors are developed to sense and monitor biochemical signals in situ in real biological environments, thus providing much more meaningful data for studying fundamental biology and diagnosing diverse health conditions. This is essential to decentralize the healthcare resources towards predictive medicine and better disease management. To meet the requirements of mechanical softness and complex biosensing, unconventional materials, and manufacturing process are demanded in developing biosensors. In this review, we summarize the fundamental approaches and the latest and representative design and fabrication to engineer soft electronics(flexible and stretchable) for wearable and implantable biochemical sensing. We will review the rational design and ingenious integration of stretchable materials, structures, and signal transducers in different application scenarios to fabricate high-performance soft biosensors. Focus is also given to how these novel biosensors can be integrated into diverse important physiological environments and scenarios in situ, such as sweat analysis, wound monitoring, and neurochemical sensing. We also rethink and discuss the current limitations,challenges, and prospects of soft biosensors. This review holds significant importance for researchers and engineers, as it assists in comprehending the overarching trends and pivotal issues within the realm of designing and manufacturing soft electronics for biochemical sensing.展开更多
Soft tissue integration around titanium(Ti)implants is weaker than that around natural teeth,compromising long-term success of Ti implants.Carbon monoxide(CO)possesses distinctive therapeutic properties,rendering it a...Soft tissue integration around titanium(Ti)implants is weaker than that around natural teeth,compromising long-term success of Ti implants.Carbon monoxide(CO)possesses distinctive therapeutic properties,rendering it as a highly promising candidate for enhancing STI.However,achieving controlled CO generation at the STI interface remains challenging.Herein,a controlled CO-releasing dual-function coating was constructed on Ti surfaces.Under near-infrared(NIR)irradiation,the designed surface could actively accelerate CO generation for antibiosis against both aerobic and anaerobic bacteria.More importantly,in the absence of NIR,the slow release of CO induces macrophage polarization from pro-inflammatory phenotype towards pro-regenerative phenotype.In a rat implantation model with induced infection,the designed surface effectively controlled the bacterial infection,alleviates accompanying inflammation and modulated immune microenvironment,leading to enhanced STI.Single-cell sequencing revealed that the coating alters the cytokine profile within the soft tissue,thereby influencing cellular functions.Differentially expressed genes in macrophages are highly enriched in the PIK3-Akt pathway.Furthermore,the cellular communication between fibroblasts and macrophages was significantly enhanced through the CXCL12/CXCL14/CXCR4 and CSF1-CSF1R ligand-receptor pair.These findings indicate that our coating showed an appealing prospect for enhancing STI around Ti implants,which would ultimately contribute to the improved long-term success of Ti implants.展开更多
基金Supported by National Natural Science Foundation of China(Grant No.52075036)Key Technologies Research and Development Program of China(Grant No.2022YFC3302204).
文摘The Chinese express delivery industry processes nearly 110 billion items in 2022,averaging an annual growth rate of 200%.Among the various types of sorting systems used for handling express items,cross-belt sorting systems stand out as the most crucial.However,despite their high degree of automation,the workload for operators has intensified owing to the surging volume of express items.In the era of Industry 5.0,it is imperative to adopt new technologies that not only enhance worker welfare but also improve the efficiency of cross-belt systems.Striking a balance between efficiency in handling express items and operator well-being is challenging.Digital twin technology offers a promising solution in this respect.A realization method of a human-machine integrated digital twin is proposed in this study,enabling the interaction of biological human bodies,virtual human bodies,virtual equipment,and logistics equipment in a closed loop,thus setting an operating framework.Key technologies in the proposed framework include a collection of heterogeneous data from multiple sources,construction of the relationship between operator fatigue and operation efficiency based on physiological measurements,virtual model construction,and an online optimization module based on real-time simulation.The feasibility of the proposed method was verified in an express distribution center.
文摘近年来,综合能源系统作为一种以多种能源形态和设备相互交互的能源系统方案得到了广泛应用和研究.然而,在面对动态复杂的多能源系统时,传统的优化调度方法往往无法满足其实时性和精准度需求.因此,本文设计了一种软深度确定性策略梯度(Soft Deep Deterministic Policy Gradient,Soft-DDPG)算法驱动的综合能源系统优化调度方法,以最小化调度周期内系统总运行成本为目标,建立设备运行综合能效评估模型,再采用Soft-DDPG算法对每个能源设备的能效调度动作进行优化控制.Soft-DDPG算法将softmax算子引入到动作值函数的计算中,有效降低了Q值高估问题.与此同时,该算法在动作选择策略中加入了随机噪声,提高了算法的学习效率.实验结果显示,本文所提出的方法解决了综合能源系统能效调度实时性差、精准度低的瓶颈问题,实现了系统的高效灵活调度,降低了系统的总运行成本.
基金supported in part by National Natural Science Foundation of China under Grant 52305304Jilin Youth Growth Technology Project under Grant 20230508147RC+2 种基金the Science and Technology Research Project of Jilin Provincial Education Department(No.JJKH20231193KJ)supported in part by the National Natural Science Foundation of China under Grant 52021003in part by the Natural Science Foundation of Jilin Province under Grant 20210101053JC.
文摘4D printed smart materials is mostly relying on thermal stimulation to actuate,limiting their widely application requiring precise and localized control of the deformations.Most existing strategies for achieving localized control rely on hetero-geneous material systems and structural design,thereby increasing design and manufacturing complexity.Here,we endow localized electrothermal,actuation,and sensing properties in electrically-driven soft actuator through parameter-encoded 4D printing.We analyzed the effects of printing parameters on shape memory properties and conductivity,and then explored the multi-directional sensing performance of the 4D printed composites.We demonstrated an integrated actuator-sensor device capable of both shape recovery and perceiving its own position and obstacles simultaneously.Moreover,it can adjust its sensing characteristics through temporary shape programming to adapt to different application scenarios.This study achieves integrated and localized actuation-sensing without the need for multi-material systems and intricate structural designs,offering an efficient solution for the intelligent and lightweight design in the fields of soft robotics,biomedical applications,and aerospace.
基金Project Supported by National Natural Science Foundation of China(51777193).
文摘The Regional Integrated Energy System(RIES)has brought new modes of development,utilization,conversion,storage of energy.The introduction of Soft Open Point(SOP)and the application of Power to Gas(P2G)technology will greatly deepen the coupling of the electricity-gas integrated energy system,improve the flexibility and safety of the operation of the power system,and bring a deal of benefits to the power system.On this background,an optimal dispatch model of RIES combined cold,heat,gas and electricity with SOP is proposed.Firstly,RIES architecture with SOP and P2G is designed and its mathematical model also is built.Secondly,on the basis of considering the optimal scheduling of combined cold,heat,gas and electricity,the optimal scheduling model for RIES was established.After that,the original model is transformed into a mixed-integer second-order cone programming model by using linearization and second-order cone relaxation techniques,and the CPLEX solver is invoked to solve the optimization problem.Finally,the modified IEEE 33-bus systemis used to analyze the benefits of SOP,P2G technology and lithium bromide absorption chillers in reducing systemnetwork loss and cost,as well as improving the system’s ability to absorb wind and solar and operating safety.
基金support from the National Science Foundation under Award Nos. EFMA-2318057, ECCS-2339495, ECCS-2334134, ECCS-2216131, and CMMI-2323917。
文摘Soft(flexible and stretchable) biosensors have great potential in real-time and continuous health monitoring of various physiological factors, mainly due to their better conformability to soft human tissues and organs, which maximizes data fidelity and minimizes biological interference.Most of the early soft sensors focused on sensing physical signals. Recently, it is becoming a trend that novel soft sensors are developed to sense and monitor biochemical signals in situ in real biological environments, thus providing much more meaningful data for studying fundamental biology and diagnosing diverse health conditions. This is essential to decentralize the healthcare resources towards predictive medicine and better disease management. To meet the requirements of mechanical softness and complex biosensing, unconventional materials, and manufacturing process are demanded in developing biosensors. In this review, we summarize the fundamental approaches and the latest and representative design and fabrication to engineer soft electronics(flexible and stretchable) for wearable and implantable biochemical sensing. We will review the rational design and ingenious integration of stretchable materials, structures, and signal transducers in different application scenarios to fabricate high-performance soft biosensors. Focus is also given to how these novel biosensors can be integrated into diverse important physiological environments and scenarios in situ, such as sweat analysis, wound monitoring, and neurochemical sensing. We also rethink and discuss the current limitations,challenges, and prospects of soft biosensors. This review holds significant importance for researchers and engineers, as it assists in comprehending the overarching trends and pivotal issues within the realm of designing and manufacturing soft electronics for biochemical sensing.
基金support from the Natural Science Foundation of China(52073224 and 52073230)the Shaanxi Provincial Science Fund for Distinguished Young Scholars(2023-JC-JQ-32)+1 种基金Key Research and Development Program of Shaanxi(2024SFYBXM-438 and 2022SF-165)Natural Science Foundation of Chongqing(CSTB2023NSCQ-MSX0225).
文摘Soft tissue integration around titanium(Ti)implants is weaker than that around natural teeth,compromising long-term success of Ti implants.Carbon monoxide(CO)possesses distinctive therapeutic properties,rendering it as a highly promising candidate for enhancing STI.However,achieving controlled CO generation at the STI interface remains challenging.Herein,a controlled CO-releasing dual-function coating was constructed on Ti surfaces.Under near-infrared(NIR)irradiation,the designed surface could actively accelerate CO generation for antibiosis against both aerobic and anaerobic bacteria.More importantly,in the absence of NIR,the slow release of CO induces macrophage polarization from pro-inflammatory phenotype towards pro-regenerative phenotype.In a rat implantation model with induced infection,the designed surface effectively controlled the bacterial infection,alleviates accompanying inflammation and modulated immune microenvironment,leading to enhanced STI.Single-cell sequencing revealed that the coating alters the cytokine profile within the soft tissue,thereby influencing cellular functions.Differentially expressed genes in macrophages are highly enriched in the PIK3-Akt pathway.Furthermore,the cellular communication between fibroblasts and macrophages was significantly enhanced through the CXCL12/CXCL14/CXCR4 and CSF1-CSF1R ligand-receptor pair.These findings indicate that our coating showed an appealing prospect for enhancing STI around Ti implants,which would ultimately contribute to the improved long-term success of Ti implants.
