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Intelligent human-computer interactive training assistant system for rail systems
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作者 Yuexuan Li Junhua Chen +1 位作者 Xiangyong Luo Han Zheng 《High-Speed Railway》 2025年第1期64-77,共14页
In recent years,railway construction in China has developed vigorously.With continuous improvements in the highspeed railway network,the focus is gradually shifting from large-scale construction to large-scale operati... In recent years,railway construction in China has developed vigorously.With continuous improvements in the highspeed railway network,the focus is gradually shifting from large-scale construction to large-scale operations.However,several challenges have emerged within the high-speed railway dispatching and command system,including the heavy workload faced by dispatchers,the difficulty of quantifying subjective expertise,and the need for effective training of professionals.Amid the growing application of artificial intelligence technologies in railway systems,this study leverages Large Language Model(LLM)technology.LLMs bring enhanced intelligence,predictive capabilities,robust memory,and adaptability to diverse real-world scenarios.This study proposes a human-computer interactive intelligent scheduling auxiliary training system built on LLM technology.The system offers capabilities including natural dialogue,knowledge reasoning,and human feedback learning.With broad applicability,the system is suitable for vocational education,guided inquiry,knowledge-based Q&A,and other training scenarios.Validation results demonstrate its effectiveness in auxiliary training,providing substantial support for educators,students,and dispatching personnel in colleges and professional settings. 展开更多
关键词 High-speed railway Dispatch training assistance Large language model human-computer interactive training assistant system Reinforcement learning
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Interaction mechanisms between green development and low-carbon economy in China:Using digital intelligence technologies as a coupling point
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作者 DU Yang XU Jun +1 位作者 YUAN Xiao YANG Qing-qing 《Ecological Economy》 2025年第1期81-99,共19页
Green development and the low-carbon economy in China have operated as parallel,distinct systems,with interactions limited to energy,industry,and technology.Guided by the concept of high-quality growth,green developm... Green development and the low-carbon economy in China have operated as parallel,distinct systems,with interactions limited to energy,industry,and technology.Guided by the concept of high-quality growth,green development—centered on sustainability principles and green targets—has focused on green living,production,industrial optimization,system-building,land-use planning,and global ecological objectives,thereby forming a uniquely Chinese green development framework.Similarly,the low-carbon economy,structured around carbon emission goals,development drivers,models of growth,management mechanisms,and international carbon responsibilities,has also developed a distinct framework.Introducing digital intelligence as a new dimension can serve as a coupling point to foster interactive mechanisms between green development and the low-carbon economy.These interactive mechanisms are reflected through smart green cloud collaboration systems and intelligent low-carbon governance platforms,using digital intelligence technology to enhance the synergy between green and low-carbon efforts in energy,carbon management,technology,innovation,governance,and the economy.Through analyzing these mechanisms,and returning to sustainability principles while responding to China's modern development philosophy,a uniquely Chinese theory and framework for green and low-carbon development can be constructed. 展开更多
关键词 green development low-carbon economy digital intelligence technology interaction
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Risk identification and safety assessment of human-computer interaction in integrated avionics based on STAMP
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作者 ZHAO Changxiao LI Hao +2 位作者 ZHANG Wei DAI Jun DONG Lei 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第3期689-706,共18页
To solve the problem of risk identification and quantitative assessment for human-computer interaction(HCI)in complex avionics systems,an HCI safety analysis framework based on system-theoretical process analysis(STPA... To solve the problem of risk identification and quantitative assessment for human-computer interaction(HCI)in complex avionics systems,an HCI safety analysis framework based on system-theoretical process analysis(STPA)and cognitive reliability and error analysis method(CREAM)is proposed.STPACREAM can identify unsafe control actions and find the causal path during the interaction of avionics systems and pilot with the help of formal verification tools automatically.The common performance conditions(CPC)of avionics systems in the aviation environment is established and a quantitative analysis of human failure is carried out.Taking the head-up display(HUD)system interaction process as an example,a case analysis is carried out,the layered safety control structure and formal model of the HUD interaction process are established.For the interactive behavior“Pilots approaching with HUD”,four unsafe control actions and35 causal scenarios are identified and the impact of common performance conditions at different levels on the pilot decision model are analyzed.The results show that HUD's HCI level gradually improves as the scores of CPC increase,and the quality of crew member cooperation and time sufficiency of the task is the key to its HCI.Through case analysis,it is shown that STPACREAM can quantitatively assess the hazards in HCI and identify the key factors that impact safety. 展开更多
关键词 AVIONICS human-computer interaction(HCI) safety assessment system-theoretic accident model and process human reliability analysis
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Identification and distribution of 13003 landslides in the northwest margin of Qinghai-Tibet Plateau based on human-computer interaction remote sensing interpretation
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作者 Wei Wang Yuan-dong Huang +8 位作者 Chong Xu Xiao-yi Shao Lei Li Li-ye Feng Hui-ran Gao Yu-long Cui Shuai Wu Zhi-qiang Yang Kai Ma 《China Geology》 CAS CSCD 2024年第2期171-187,共17页
The periphery of the Qinghai-Tibet Plateau is renowned for its susceptibility to landslides.However,the northwestern margin of this region,characterised by limited human activities and challenging transportation,remai... The periphery of the Qinghai-Tibet Plateau is renowned for its susceptibility to landslides.However,the northwestern margin of this region,characterised by limited human activities and challenging transportation,remains insufficiently explored concerning landslide occurrence and dispersion.With the planning and construction of the Xinjiang-Xizang Railway,a comprehensive investigation into disastrous landslides in this area is essential for effective disaster preparedness and mitigation strategies.By using the human-computer interaction interpretation approach,the authors established a landslide database encompassing 13003 landslides,collectively spanning an area of 3351.24 km^(2)(36°N-40°N,73°E-78°E).The database incorporates diverse topographical and environmental parameters,including regional elevation,slope angle,slope aspect,distance to faults,distance to roads,distance to rivers,annual precipitation,and stratum.The statistical characteristics of number and area of landslides,landslide number density(LND),and landslide area percentage(LAP)are analyzed.The authors found that a predominant concentration of landslide origins within high slope angle regions,with the highest incidence observed in intervals characterised by average slopes of 20°to 30°,maximum slope angle above 80°,along with orientations towards the north(N),northeast(NE),and southwest(SW).Additionally,elevations above 4.5 km,distance to rivers below 1 km,rainfall between 20-30 mm and 30-40 mm emerge as particularly susceptible to landslide development.The study area’s geological composition primarily comprises Mesozoic and Upper Paleozoic outcrops.Both fault and human engineering activities have different degrees of influence on landslide development.Furthermore,the significance of the landslide database,the relationship between landslide distribution and environmental factors,and the geometric and morphological characteristics of landslides are discussed.The landslide H/L ratios in the study area are mainly concentrated between 0.4 and 0.64.It means the landslides mobility in the region is relatively low,and the authors speculate that landslides in this region more possibly triggered by earthquakes or located in meizoseismal area. 展开更多
关键词 LANDSLIDES human-computer interaction interpretation Landslide database Spatial distribution Earthquake RAINFALL Human engineering activity Qinghai-Tibet Plateau Geological hazards survey engineering
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Advances in applying somatosensory interaction technology in geriatric care:A bibliometric analysis
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作者 Changle Pei Weibo Lyu +4 位作者 Jingxia Liu Yan Wang Wenjia Ye Zhou Zhou Kangyao Cheng 《International Journal of Nursing Sciences》 CSCD 2024年第5期571-577,I0003,I0004,共9页
Objectives:Somatosensory Interaction Technology(SIT)is used in various aspects of geriatric care.We aimed to conduct a bibliometric analysis to summarize relevant publications and visualize publication characteristics... Objectives:Somatosensory Interaction Technology(SIT)is used in various aspects of geriatric care.We aimed to conduct a bibliometric analysis to summarize relevant publications and visualize publication characteristics,current hotspots,and development trends,thereby inspiring subsequent researches.Methods:We searched theWeb of Science Core Collection database for publications on the application of SIT in geriatric care.Bibliometric visualization and clustering analysis were performed using VOSviewer V1.6.18 Software,while keywords burst detection analysis was conducted with CiteSpace 6.1.R6 Software.Results:After screening,a total of 1,019 publications were included.The number of publications on SIT in geriatric care is gradually increasing,exhibiting a rapid growth rate.The United States,Canada,and Australia led in terms of publication volume.Keyword clustering analysis identified major research hotspots:crisis warning,somatic abilities,rehabilitation training and psychosocial support.Initial studies primarily explored themes such as recovery,movement,systems,and later shifted towards gait analysis,muscle strength,parameters,and home-based care.More recently,research themes have evolved to dementia,machine learning,and gamification.Conclusions:SIT is innovative for promoting active aging,advancing intelligent healthcare,and elevating the daily quality of life for older adults in clinical and domestic settings.Applications of SIT can be categorized into early warning systems for crises,detailed analyses of physical conditions,rehabilitation enhancement,and support for psychosocial health.Research trends have transitioned from whole-body recognition to precise feedback,from a focus on physical health to mental health,and from technical feasibility to user-friendliness.Future research should focus on developing accessible and user-friendly devices,fostering interdisciplinary collaborations for innovation,expanding research to address both the physical and mental health needs of diverse older adults,and integrating emerging technologies to enhance data precision and accelerate the development of intelligent platforms. 展开更多
关键词 BIBLIOMETRICS Data visualization Geriatric care Health management REVIEW Somatosensory interaction technology
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Numerical Modeling of Ship-Ice-Water Interaction for Freerunning Ships in Pack Ice
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作者 ZOU Ming ZOU Zao−jian +1 位作者 ZOU Lu ZHU Sheng−tao 《船舶力学》 北大核心 2025年第6期878-887,共10页
Ice-going ships play a crucial role in polar transportation and resource extraction.Different from the existing modeling approach which assumes that ships remain stationary,dynamic overset grid technology and DFBI(Dyn... Ice-going ships play a crucial role in polar transportation and resource extraction.Different from the existing modeling approach which assumes that ships remain stationary,dynamic overset grid technology and DFBI(Dynamic Fluid-Body Interaction)method are employed in this paper to enable the free-running motion of the ship in modeling.A numerical model capable of simulating a ship navigating through pack ice area is proposed,which uses Computational Fluid Dynamics(CFD)method to solve the flow field and applies the Discrete Element Method(DEM)to simulate ship-ice and ice-ice interactions.Besides,the proposed high-precision method for generating pack ice area can be used in conjunction with the proposed numerical model.By comparing the numerical results with the available model test data and experimental observations,the effectiveness of the numerical model is validated,demonstrating its strong capability of predicting resistance and simulating ship navigation in pack ice,as well as its significant potential and applicability for further studies. 展开更多
关键词 pack ice ship-ice-water interaction CFD-DEM dynamic overset grid technology ship resistance
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A haptic feedback glove for virtual piano interaction
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作者 Yifan FU Jialin LIU +1 位作者 Xu LI Xiaoying SUN 《虚拟现实与智能硬件(中英文)》 2025年第1期95-110,共16页
Background Haptic feedback plays a crucial role in virtual reality(VR)interaction,helping to improve the precision of user operation and enhancing the immersion of the user experience.Instrumental haptic feedback in v... Background Haptic feedback plays a crucial role in virtual reality(VR)interaction,helping to improve the precision of user operation and enhancing the immersion of the user experience.Instrumental haptic feedback in virtual environments is primarily realized using grounded force or vibration feedback devices.However,improvements are required in terms of the active space and feedback realism.Methods We propose a lightweight and flexible haptic feedback glove that can haptically render objects in VR environments via kinesthetic and vibration feedback,thereby enabling users to enjoy a rich virtual piano-playing experience.The kinesthetic feedback of the glove relies on a cable-pulling mechanism that rotates the mechanism and pulls the two cables connected to it,thereby changing the amount of force generated to simulate the hardness or softness of the object.Vibration feedback is provided by small vibration motors embedded in the bottom of the fingertips of the glove.We designed a piano-playing scenario in the virtual environment and conducted user tests.The evaluation metrics were clarity,realism,enjoyment,and satisfaction.Results A total of 14 subjects participated in the test,and the results showed that our proposed glove scored significantly higher on the four evaluation metrics than the nofeedback and vibration feedback methods.Conclusions Our proposed glove significantly enhances the user experience when interacting with virtual objects. 展开更多
关键词 Wearable device human-computer interaction Virtual reality Haptic feedback
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Analysis of the Construction of Teacher-Student Interaction Mode in Piano Teaching in Normal Universities
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作者 Zitong Li 《Journal of Contemporary Educational Research》 2025年第4期81-90,共10页
In the modern higher education music curriculum system,the teacher-student interaction mode is a key factor affecting the effectiveness of piano teaching.However,the current teacher-student interaction mode in piano t... In the modern higher education music curriculum system,the teacher-student interaction mode is a key factor affecting the effectiveness of piano teaching.However,the current teacher-student interaction mode in piano teaching still has limitations,such as one-way transmission and a lack of personalized feedback.Based on constructivist learning theory and social interaction theory,combined with information technology,this paper explores the optimization strategy of interaction mode in the piano teaching process of normal universities.This study adopts classroom observation and interview methods to analyze the impact of different interaction modes on students’piano learning effectiveness,learning engagement,and autonomous learning ability.The research results show that the constructivist interactive teaching mode supported by information technology can significantly enhance students’interest in learning and playing skills,optimize the classroom teaching atmosphere,and promote the improvement of their comprehensive literacy. 展开更多
关键词 Piano teaching interactive teaching mode CONSTRUCTIVISM Information technology Autonomous learning
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Vision-Based Hand Gesture Recognition for Human-Computer Interaction——A Survey 被引量:2
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作者 GAO Yongqiang LU Xiong +4 位作者 SUN Junbin TAO Xianglin HUANG Xiaomei YAN Yuxing LIU Jia 《Wuhan University Journal of Natural Sciences》 CAS CSCD 2020年第2期169-184,共16页
Recently,vision-based gesture recognition(VGR)has become a hot research spot in human-computer interaction(HCI).Unlike other gesture recognition methods with data gloves or other wearable sensors,vision-based gesture ... Recently,vision-based gesture recognition(VGR)has become a hot research spot in human-computer interaction(HCI).Unlike other gesture recognition methods with data gloves or other wearable sensors,vision-based gesture recognition could lead to more natural and intuitive HCI interactions.This paper reviews the state-of-the-art vision-based gestures recognition methods,from different stages of gesture recognition process,i.e.,(1)image acquisition and pre-processing,(2)gesture segmentation,(3)gesture tracking,(4)feature extraction,and(5)gesture classification.This paper also analyzes the advantages and disadvantages of these various methods in detail.Finally,the challenges of vision-based gesture recognition in haptic rendering and future research directions are discussed. 展开更多
关键词 vision-based gesture recognition human-computer interaction STATE-OF-THE-ART feature extraction
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Reform of Human-Computer Interaction Course based on Mobile Application Interaction Design
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作者 Siyang Lu Xiang Wei 《计算机教育》 2020年第12期122-125,共4页
With the popularity of new intelligent mobile devices in people’s lives,the development of mobile applications has paid increasing attention to the interactive experience of users.As the content of traditional Human-... With the popularity of new intelligent mobile devices in people’s lives,the development of mobile applications has paid increasing attention to the interactive experience of users.As the content of traditional Human-Computer Interaction(HCI)course and teaching material is out of date,it cannot meet the needs of mobile application interaction design and enterprises for students.Therefore,we need a new generation HCI course based on intelligent mobile devices to study the relationship between users and systems.The HCI course not only teaches students HCI theory and model,but also needs to cultivate students’interaction-oriented design practical ability.This paper proposes a set of HCI teaching material design and teaching methods for improving HCI class quality on mobile application interaction design,so as to make students more suitable for the employment requirements of enterprises. 展开更多
关键词 human-computer interaction software engineering mobile application interaction design
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Design and Implementation of the Image Interactive System Based on Human-Computer Interaction
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作者 Shanwei Song Yuting Wu Fang Zhang 《Intelligent Information Management》 2010年第5期334-337,共4页
Based on the traditional Human-Computer Interaction method which is mainly touch input system, the way of capturing the movement of people by using cameras is proposed. This is a convenient technique which can provide... Based on the traditional Human-Computer Interaction method which is mainly touch input system, the way of capturing the movement of people by using cameras is proposed. This is a convenient technique which can provide users more experience. In the article, a new way of detecting moving things is given on the basis of development of the image processing technique. The system architecture decides that the communication should be used between two different applications. After considered, named pipe is selected from many ways of communication to make sure that video is keeping in step with the movement from the analysis of the people moving. According to a large amount of data and principal knowledge, thinking of the need of actual project, a detailed system design and realization is finished. The system consists of three important modules: detecting of the people's movement, information transition between applications and video showing in step with people's movement. The article introduces the idea of each module and technique. 展开更多
关键词 human-computer interaction IMAGE PROCESSING MOVING OBJECT Detection COMMUNICATION Response
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Dynamic constraint and objective generation approach for real-time train rescheduling model under human-computer interaction
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作者 Kai Liu Jianrui Miao +2 位作者 Zhengwen Liao Xiaojie Luan Lingyun Meng 《High-Speed Railway》 2023年第4期248-257,共10页
Real-time train rescheduling plays a vital role in railway transportation as it is crucial for maintaining punctuality and reliability in rail operations.In this paper,we propose a rescheduling model that incorporates... Real-time train rescheduling plays a vital role in railway transportation as it is crucial for maintaining punctuality and reliability in rail operations.In this paper,we propose a rescheduling model that incorporates constraints and objectives generated through human-computer interaction.This approach ensures that the model is aligned with practical requirements and daily operational tasks while facilitating iterative train rescheduling.The dispatcher’s empirical knowledge is integrated into the train rescheduling process using a human-computer interaction framework.We introduce six interfaces to dynamically construct constraints and objectives that capture human intentions.By summarizing rescheduling rules,we devise a rule-based conflict detection-resolution heuristic algorithm to effectively solve the formulated model.A series of numerical experiments are presented,demonstrating strong performance across the entire system.Furthermore,theflexibility of rescheduling is enhanced through secondary analysis-driven solutions derived from the outcomes of humancomputer interactions in the previous step.This proposed interaction method complements existing literature on rescheduling methods involving human-computer interactions.It serves as a tool to aid dispatchers in identifying more feasible solutions in accordance with their empirical rescheduling strategies. 展开更多
关键词 Real-time train rescheduling human-computer interaction Rule-based heuristic algorithm Secondary rescheduling
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Mixed Reality-based Interactive Technology for Aircraft Cabin Assembly 被引量:12
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作者 LI Shiqi PENG Tao WANG Junfeng XU Chi 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2009年第3期403-409,共7页
Due to the narrowness of space and the complexity of structure, the assembly of aircraft cabin has become one of the major bottlenecks in the whole manufacturing process. To solve the problem, at the beginning of airc... Due to the narrowness of space and the complexity of structure, the assembly of aircraft cabin has become one of the major bottlenecks in the whole manufacturing process. To solve the problem, at the beginning of aircraft design, the different stages of the lifecycle of aircraft must be thought about, which include the trial manufacture, assembly, maintenance, recycling and destruction of the product. Recently, thanks to the development of the virtual reality and augmented reality, some low-cost and fast solutions are found for the product assembly. This paper presents a mixed reality-based interactive technology for the aircraft cabin assembly, which can enhance the efficiency of the assemblage in a virtual environment in terms of vision, information and operation. In the mixed reality-based assembly environment, the physical scene can be obtained by a camera and then generated by a computer. The virtual parts, the features of visual assembly, the navigation information, the physical parts and the physical assembly environment will be mixed and presented in the same assembly scene. The mixed or the augmented information will provide some assembling information as a detailed assembly instruction in the mixed reality-based assembly environment. Constraint proxy and its match rules help to reconstruct and visualize the restriction relationship among different parts, and to avoid the complex calculation of constraint's match. Finally, a desktop prototype system of virtual assembly has been built to assist the assembly verification and training with the virtual hand. 展开更多
关键词 virtual assembly human-computer interaction mixed reality information augmentation constraints navigation
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Research on the Application of Flexible Electronics Technology in Wearable Devices
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作者 Sucheng Yu 《World Journal of Engineering and Technology》 2024年第4期1024-1033,共10页
This study employs theoretical analysis to explore the application prospects of flexible electronics technology in wearable devices. The research first reviews the development history and theoretical foundations of fl... This study employs theoretical analysis to explore the application prospects of flexible electronics technology in wearable devices. The research first reviews the development history and theoretical foundations of flexible electronics technology, including materials science, electronic engineering, and human-computer interaction theory. Through systematic analysis, the study evaluates the theoretical potential of flexible displays, flexible sensors, and flexible energy storage devices in wearable technology. The research finds that flexible electronics technology can significantly improve the comfort, functionality, and durability of wearable devices. Theoretical analysis indicates that flexible sensors have unique advantages in physiological monitoring and human-computer interaction, while flexible displays and batteries may revolutionize the form and usage patterns of wearable devices. However, the study also points out theoretical challenges faced by flexible electronics technology, such as material stability and feasibility of large-scale manufacturing. To address these challenges, the research proposes an interdisciplinary research framework, emphasizing the synergistic innovation of materials science, electronic engineering, and ergonomics. Finally, the study envisions the theoretical prospects of integrating flexible electronics with other emerging technologies, providing directions for future research. 展开更多
关键词 Flexible Electronics Wearable Devices Flexible Sensors human-computer interaction Materials Science
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Research on the Multi-Interactive Intelligent Teaching Model of College English in the Information Technology Environment
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作者 MA Huan 《International English Education Research》 2019年第3期43-45,共3页
The multi-interactive teaching mode based on the information technology is a new teaching mode, which promotes students' autonomous learning and research-oriented learning through the online and offline effective ... The multi-interactive teaching mode based on the information technology is a new teaching mode, which promotes students' autonomous learning and research-oriented learning through the online and offline effective interaction in and out of class, fully embodying the principle of the learning-orientation. Based on this, this paper focuses on the connotation and the theoretical basis o f the multi-interactive teaching model, as well as its implementation practices and characteristics, with a view o f providing help to improve the quality of the college English teaching. 展开更多
关键词 Information technology environment COLLEGE ENGLISH multiple interaction intelligent TEACHING mode RESEARCH
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Network Interactive Teaching in High School Information Technology Classroom
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作者 MAOQili 《外文科技期刊数据库(文摘版)教育科学》 2022年第1期075-078,共4页
Network interactive teaching is an advanced teaching idea. Under the background of the continuous development of information technology, the teaching content and information technology are combined to achieve the seam... Network interactive teaching is an advanced teaching idea. Under the background of the continuous development of information technology, the teaching content and information technology are combined to achieve the seamless connection of teaching links such as "speaking, thinking, practice and application" in teaching activities. Information technology as a technical course, its teaching focus is to improve students' ability to use information technology. Therefore, in the process of continuous development and improvement of classroom interactive network teaching, senior high school information technology teachers should carry out the teaching idea of "student-centered", give play to the student-centered status, so as to improve the quality of classroom teaching. Due to the particularity and natural advantages of the subject, information technology can conveniently realize the development of interactive teaching mode based on network in the classroom. This paper mainly discusses the practice and exploration of network interactive teaching in high school information technology classroom and its application effect analysis. 展开更多
关键词 high school information technology classroom NETWORK interactive teaching
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Facilitating IT outsourcing through improving buyer-vendor interaction in outsourcing life cycle
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作者 谢刚 梅姝娥 《Journal of Southeast University(English Edition)》 EI CAS 2011年第1期96-100,共5页
For a clear understanding of how to foster necessary attributes of partnerships that promote a closer relationship for achieving outsourcing success,this paper tries to explore the role of interaction.Based on empiric... For a clear understanding of how to foster necessary attributes of partnerships that promote a closer relationship for achieving outsourcing success,this paper tries to explore the role of interaction.Based on empirical data from a logistics and procurement flat system outsourcing case and earlier research,the industrial network approach and the international marketing and purchasing interaction model are used to analyze the nature of interaction in a three-phased outsourcing life cycle,particularly,characteristics and activities of the transition phase are identified.The findings reveal that developing a relationship between partners requires an industrial network perspective.Improving the key aspects of interaction,information and knowledge sharing,communication and collaborative participation,involved in the important events of three phases would contribute to enhance the relationships performance.The key aspects of interaction should take place among the network actors and not just between buyers and vendors. 展开更多
关键词 information technology(IT) outsourcing outsourcing life cycle interaction
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Microscale thermophoresis in the investigation of biomolecular interactions 被引量:4
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作者 Qian Wang Jing Wang +3 位作者 Shuxiang Song Guiwang Zhu Ze Cao Zhenming Liu 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2020年第9期656-665,共10页
Accurate characterization of the interactions between biomolecules not only provides fundamental insights into cellular processes but also paves the way for drug discovery and development. With recent increases in thr... Accurate characterization of the interactions between biomolecules not only provides fundamental insights into cellular processes but also paves the way for drug discovery and development. With recent increases in throughput and sensitivity, biophysical technologies have become prominent tools for studying biomolecular interactions. Biophysical techniques that can reduce costs, shorten detection time, simplify the complexity of the system under analysis, and simultaneously provide high-quality data content are particularly favored. Here, we summarize the qualitative and quantitative analysis of biomolecular interactions using Micro Scale Thermophoresis(MST), as well as extend the application of MST functions to explore thermodynamics, enzyme kinetics and protein folding-unfolding processes. MST has emerged as a simple and powerful biophysical approach for identifying and quantifying binding events based on the movement of molecules along microscopic temperature gradients. The advantages of MST over other competitive biophysical techniques include freedom from immobilization, rapid analysis times, lower sample consumption, and the ability to analyze binding affinities in cell lysates. This article discusses the instrumental setups, principles, experimental workflows, and examples of MST application in practice. 展开更多
关键词 Biomolecular interactions Biophysical technologies Micro Scale Thermophoresis
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Virtual brain surgery simulation system based on haptic interaction 被引量:3
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作者 张小瑞 Zhu Jiandong +4 位作者 Sun Wei Norman I.Badler Song Aiguo Niu Jianwei Liu Jia 《High Technology Letters》 EI CAS 2015年第2期185-191,共7页
To improve the accuracy and interactivity of soft tissue delormatlon simulation, a new plate spring model based on physics is proposed. The model is parameterized and thus can be adapted to simulate different organs. ... To improve the accuracy and interactivity of soft tissue delormatlon simulation, a new plate spring model based on physics is proposed. The model is parameterized and thus can be adapted to simulate different organs. Different soft tissues are modeled by changing the width, number of pieces, thickness, and length of a single plate spring. In this paper, the structural design, calcula- tion of soft tissue deformation and real-time feedback operations of our system are also introduced. To evaluate the feasibility of the system and validate the model, an experimental system of haptic in- teraction, in which users can use virtual hands to pull virtual brain tissues, is built using PHANTOM OMNI devices. Experimental results show that the proposed system is stable, accurate and promising for modeling instantaneous soft tissue deformation. 展开更多
关键词 haptic feedback human-computer interaction surgery simulation soft tissue deformation
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Using Mobile Application to Improve Doctor-Patient Interaction in Healthcare Delivery System 被引量:2
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作者 Ekwonwune Emmanuel Nwabueze Onuoha Oju 《E-Health Telecommunication Systems and Networks》 2019年第3期23-34,共12页
The use of mobile applications for healthcare has become a focal point of innovation that could aid patients in their everyday healthcare management. Mobile applications can contribute to increasing the effectiveness ... The use of mobile applications for healthcare has become a focal point of innovation that could aid patients in their everyday healthcare management. Mobile applications can contribute to increasing the effectiveness and reducing the costs of healthcare delivery as well as preventing illnesses through behaviour change. This paper presents model of an interactive mobile healthcare application that facilitates the needs between doctors and patients. The proposed mobile application will provide optimal communication to several parties in the healthcare sector such as patients, doctors and pharmacists for better healthcare services and delivery. The software development methodology adopted was Object Oriented Analysis and Design Methodology (OOADM). Our mobile application is developed for Android platform and HTML, CSS and JS were used at the front-end while Angula JS, PHP and MYSQL powered the back-end. 展开更多
关键词 MOBILE Healthcare interactIVE technology APPLICATION COMMUNICATION
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