Manganese-containing superoxide dismutase (Mn-SOD) activity in lung cancer tissues from 5 patients with pulmonary carcinoma were measured by the nitrite formation method, lipid peroxide (LPO) values being measured by ...Manganese-containing superoxide dismutase (Mn-SOD) activity in lung cancer tissues from 5 patients with pulmonary carcinoma were measured by the nitrite formation method, lipid peroxide (LPO) values being measured by spectrophotometry of thio-barbituric acid reaction. The results obtained show that Mn-SOD activity exhibits most evidently in lung cancer tissues, less evidently in peripheral tissues around the lung cancer, but the least in normal peripheral lung tissues, indicating a declined tendency as definitely proved by statistical treatment (P<0.01). In addition, LPO values are found to be lower in lung cancer tissues than those in normal peripheral tissues.展开更多
In the early 1990s,shortly after we identified the genetic defect in FMR1 that results in fragile X syndrome（Verkerk et al.,1991）,I attended a conference sponsored by the US National Fragile X Foundation.This biannu...In the early 1990s,shortly after we identified the genetic defect in FMR1 that results in fragile X syndrome（Verkerk et al.,1991）,I attended a conference sponsored by the US National Fragile X Foundation.This biannual meeting mixes families and scientists in a very productive and enlightening way.展开更多
The concluding observations are comments and recommendations made by the treaty bodies to the country after reviewing the reports of specific State Parties with a view to monitoring the State Parties’compliance.altho...The concluding observations are comments and recommendations made by the treaty bodies to the country after reviewing the reports of specific State Parties with a view to monitoring the State Parties’compliance.although these opinions are not legally binding,they do have a certain authority.When deciding whether to endorse this authority and accept the recommendations,the State party will focus on the legality of the concluding observations.The legality of the concluding observations is influenced by three factors,the first one is the formal relevance between the recommendations and the relevant treaty provisions;the second one is the substantive relevance between them;the third is the extent to which the treaty interpretation rules are followed.For the concluding observations of treaty bodies against china,we should treat them separately.The feasible recommendations that are most closely related to treaty obligations should be adopted as far as possible.appropriate consideration should be given to general policy recommendations,and recommendations that are completely unrelated to treaty obligations can be ignored.展开更多
Objective: to study and analyze the effect of human nature nursing for pregnant women in the whole process of delivery. Methods: contrastive analysis strategy was selected to analyze the effect of the observation grou...Objective: to study and analyze the effect of human nature nursing for pregnant women in the whole process of delivery. Methods: contrastive analysis strategy was selected to analyze the effect of the observation group and the control group. The observation group was treated with whole-process humanistic nursing, while the control group was treated with routine nursing. Results: after systematic observation and analysis, it can be found that the amount of bleeding at 2h and 24h postpartum in the observation group is significantly less than that in the control group, there is a significant difference (P < 0.05), and the observation group of patients with a great improvement in mood, which is difficult to achieve and realize by the traditional delivery nursing work. Conclusion: humanized nursing strategy in the whole process of delivery is of great value and plays an important role in the psychological aspects of pregnant and parturient women. It is worth popularizing in the development of clinical medicine in the future.展开更多
[Objectives]To explore the effect of the extract of Growgx yeast fermentation product on ultraviolet A(UVA)-induced photo-aging of human skin fibroblasts(HFF-1)and its specific mechanisms from the level of cell biolog...[Objectives]To explore the effect of the extract of Growgx yeast fermentation product on ultraviolet A(UVA)-induced photo-aging of human skin fibroblasts(HFF-1)and its specific mechanisms from the level of cell biology,and discussed the application of the Growgx yeast fermentation product extract for skin aging.[Methods]A photo-aging model of HFF-1 cells was induced by UVA radiation meter,and it was given different concentrations of Growgx for intervention.The proliferation activity of the HFF-1 cells was detected with MTT method,and their migration and invasion ability was measured by scratch test.The SOD,HYP and MDA levels were detected with corresponding kits.After oxygen infusion apparatus assisted facial skin administration,the repair of the skin was observed through the VISIA skin tester.[Results]The survival rate of HFF-1 cells was reduced significantly by UVA with an irradiation dose of 10.8 J/cm2(P<0.05),while Growgx significantly increased their survival rate(P<0.001)and sped up the repair of damaged cells.Growgx promoted the production of SOD(P<0.05),reduced the level of MDA(P<0.05),and increased the level of HYP(P<0.05).Growgx effectively inhibited UVA-induced photo-aging of HFF-1 cells.The mechanism may be related to accelerating cell damage repair,up-regulating SOD and HYP expression levels,and reducing MDA expression level.The clinical observation showed that Growgx effectively improved skin spots and pores,making the skin smoother and more delicate.[Conclusions]Growgx can effectively fight against photo-aging caused by ultraviolet rays,and can significantly improve skin wrinkles.展开更多
My creative focus and interest has always been the state of human existence.Compared with grand narratives,it is often the most inadvertent,subtle actions that become my entry point.I starl a dialogue with myself by c...My creative focus and interest has always been the state of human existence.Compared with grand narratives,it is often the most inadvertent,subtle actions that become my entry point.I starl a dialogue with myself by carefully observing and deeply analyzing those subtle yet tense behaviors.Through this process,I discover and develop my own creative system to affirm the value of my existence in my work.展开更多
The transformation from authoritative to user-generated data landscapes has garnered considerable attention,notably with the proliferation of crowdsourced geospatial data.Facilitated by advancements in digital technol...The transformation from authoritative to user-generated data landscapes has garnered considerable attention,notably with the proliferation of crowdsourced geospatial data.Facilitated by advancements in digital technology and high-speed communication,this paradigm shift has democratized data collection,obliterating traditional barriers between data producers and users.While previous literature has compartmentalized this subject into distinct platforms and application domains,this review offers a holistic examination of crowdsourced geospatial data.Employing a narrative review approach due to the interdisciplinary nature of the topic,we investigate both human and Earth observations through crowdsourced initiatives.This review categorizes the diverse applications of these data and rigorously examines specific platforms and paradigms pertinent to data collection.Furthermore,it addresses salient challenges,encompassing data quality,inherent biases,and ethical dimensions.We contend that this thorough analysis will serve as an invaluable scholarly resource,encapsulating the current state-of-the-art in crowdsourced geospatial data,and offering strategic directions for future interdisciplinary research and applications across various sectors.展开更多
文摘Manganese-containing superoxide dismutase (Mn-SOD) activity in lung cancer tissues from 5 patients with pulmonary carcinoma were measured by the nitrite formation method, lipid peroxide (LPO) values being measured by spectrophotometry of thio-barbituric acid reaction. The results obtained show that Mn-SOD activity exhibits most evidently in lung cancer tissues, less evidently in peripheral tissues around the lung cancer, but the least in normal peripheral lung tissues, indicating a declined tendency as definitely proved by statistical treatment (P<0.01). In addition, LPO values are found to be lower in lung cancer tissues than those in normal peripheral tissues.
基金support and guidance of colleagues andcoworkers across the genetics community and for the contributions to my own research from the Cullen Foundation, the FRAXA foundation, the Azrieli Foundation(Brain Canada), and the US NIH (HD084802, HD083092 and NS051630)
文摘In the early 1990s,shortly after we identified the genetic defect in FMR1 that results in fragile X syndrome（Verkerk et al.,1991）,I attended a conference sponsored by the US National Fragile X Foundation.This biannual meeting mixes families and scientists in a very productive and enlightening way.
文摘The concluding observations are comments and recommendations made by the treaty bodies to the country after reviewing the reports of specific State Parties with a view to monitoring the State Parties’compliance.although these opinions are not legally binding,they do have a certain authority.When deciding whether to endorse this authority and accept the recommendations,the State party will focus on the legality of the concluding observations.The legality of the concluding observations is influenced by three factors,the first one is the formal relevance between the recommendations and the relevant treaty provisions;the second one is the substantive relevance between them;the third is the extent to which the treaty interpretation rules are followed.For the concluding observations of treaty bodies against china,we should treat them separately.The feasible recommendations that are most closely related to treaty obligations should be adopted as far as possible.appropriate consideration should be given to general policy recommendations,and recommendations that are completely unrelated to treaty obligations can be ignored.
文摘Objective: to study and analyze the effect of human nature nursing for pregnant women in the whole process of delivery. Methods: contrastive analysis strategy was selected to analyze the effect of the observation group and the control group. The observation group was treated with whole-process humanistic nursing, while the control group was treated with routine nursing. Results: after systematic observation and analysis, it can be found that the amount of bleeding at 2h and 24h postpartum in the observation group is significantly less than that in the control group, there is a significant difference (P < 0.05), and the observation group of patients with a great improvement in mood, which is difficult to achieve and realize by the traditional delivery nursing work. Conclusion: humanized nursing strategy in the whole process of delivery is of great value and plays an important role in the psychological aspects of pregnant and parturient women. It is worth popularizing in the development of clinical medicine in the future.
基金Supported by General Program of Guangxi Natural Science Foundation(2018GXNSFAA138098).
文摘[Objectives]To explore the effect of the extract of Growgx yeast fermentation product on ultraviolet A(UVA)-induced photo-aging of human skin fibroblasts(HFF-1)and its specific mechanisms from the level of cell biology,and discussed the application of the Growgx yeast fermentation product extract for skin aging.[Methods]A photo-aging model of HFF-1 cells was induced by UVA radiation meter,and it was given different concentrations of Growgx for intervention.The proliferation activity of the HFF-1 cells was detected with MTT method,and their migration and invasion ability was measured by scratch test.The SOD,HYP and MDA levels were detected with corresponding kits.After oxygen infusion apparatus assisted facial skin administration,the repair of the skin was observed through the VISIA skin tester.[Results]The survival rate of HFF-1 cells was reduced significantly by UVA with an irradiation dose of 10.8 J/cm2(P<0.05),while Growgx significantly increased their survival rate(P<0.001)and sped up the repair of damaged cells.Growgx promoted the production of SOD(P<0.05),reduced the level of MDA(P<0.05),and increased the level of HYP(P<0.05).Growgx effectively inhibited UVA-induced photo-aging of HFF-1 cells.The mechanism may be related to accelerating cell damage repair,up-regulating SOD and HYP expression levels,and reducing MDA expression level.The clinical observation showed that Growgx effectively improved skin spots and pores,making the skin smoother and more delicate.[Conclusions]Growgx can effectively fight against photo-aging caused by ultraviolet rays,and can significantly improve skin wrinkles.
文摘My creative focus and interest has always been the state of human existence.Compared with grand narratives,it is often the most inadvertent,subtle actions that become my entry point.I starl a dialogue with myself by carefully observing and deeply analyzing those subtle yet tense behaviors.Through this process,I discover and develop my own creative system to affirm the value of my existence in my work.
基金supported by the Faculty Startup Fund of the College of Arts and Sciences at Emory University.
文摘The transformation from authoritative to user-generated data landscapes has garnered considerable attention,notably with the proliferation of crowdsourced geospatial data.Facilitated by advancements in digital technology and high-speed communication,this paradigm shift has democratized data collection,obliterating traditional barriers between data producers and users.While previous literature has compartmentalized this subject into distinct platforms and application domains,this review offers a holistic examination of crowdsourced geospatial data.Employing a narrative review approach due to the interdisciplinary nature of the topic,we investigate both human and Earth observations through crowdsourced initiatives.This review categorizes the diverse applications of these data and rigorously examines specific platforms and paradigms pertinent to data collection.Furthermore,it addresses salient challenges,encompassing data quality,inherent biases,and ethical dimensions.We contend that this thorough analysis will serve as an invaluable scholarly resource,encapsulating the current state-of-the-art in crowdsourced geospatial data,and offering strategic directions for future interdisciplinary research and applications across various sectors.
