Aromatic amines represent one of the most prevalent functional groups in bioactive molecules,serving as cornerstones in natural products and pharmaceutical scaffolds[1].However,alternative strategies that utilize thes...Aromatic amines represent one of the most prevalent functional groups in bioactive molecules,serving as cornerstones in natural products and pharmaceutical scaffolds[1].However,alternative strategies that utilize these compounds have remained largely underexplored.For decades,strategies like the Sandmeyer reaction,despite being a foundational method for amine derivatization,have suffered from stoichiometric copper consumption.展开更多
文摘Aromatic amines represent one of the most prevalent functional groups in bioactive molecules,serving as cornerstones in natural products and pharmaceutical scaffolds[1].However,alternative strategies that utilize these compounds have remained largely underexplored.For decades,strategies like the Sandmeyer reaction,despite being a foundational method for amine derivatization,have suffered from stoichiometric copper consumption.