Water is an indispensable resource for life. In the district of Ahomadégbé in Benin, although most of the population has access to improved water sources, in their homes, residents consume poor water quality...Water is an indispensable resource for life. In the district of Ahomadégbé in Benin, although most of the population has access to improved water sources, in their homes, residents consume poor water quality due to microbiological contamination during transport and storage. To identify necessary actions needed to improve household drinking water quality, the present study aims to analyze the knowledge, attitudes, and practices the district of Ahomadégbé’s population regarding household drinking water treatments methods. A study was conducted, where 377 residents were interviewed using an individual questionnaire and 82 participants were selected for eight focus groups to determine the population’s knowledge, attitudes, and practices. More than 65% of the district’s population knew some methods of water treatment at home. In practice, however, they lacked the knowledge to apply the different water treatment methods and only 6.1% of the population used at least one method of water treatment at home, even if it was not always adapted. The water treatment methods residents used were Alum (KAl(SO4)2·12 H2O, chemical decantation method), filtration on tissues, and disinfection by boiling. Ineffective home water treatment methods, such as oil and cresol were also used. The population is aware of water contamination during transport and storage. Unfortunately, most residents surveyed do not treat water before consumption, and those who treat it, use inappropriate methods. Thus, people must be made aware of the health benefits of using effective home water treatment methods and their correct use.展开更多
Background: Catheter related bloodstream infections (CRIs) are a major cause of morbidity, mortality and prolonged hospitalization in pediatric patients with home parenteral nutrition (HPN). In recent years, new proph...Background: Catheter related bloodstream infections (CRIs) are a major cause of morbidity, mortality and prolonged hospitalization in pediatric patients with home parenteral nutrition (HPN). In recent years, new prophylactic and treatment options have been evaluated to reduce the incidence of CRIs and infection related catheter removals. In children, two retrospective studies have shown the efficacy of ethanol lock treatment (ELT) in reducing the incidence of CRIs in pediatric oncology patients. However, prospective data are missing. Our aim of the present study was to evaluate prospectively the effect of ELT on the cure and recurrence rate of CRIs, duration of hospitalization and antibiotic use in HPN pediatric patients. Methods: HPN children older than three months with a clinical suspicion of a CRI were included and randomised to ELT or standard flushing treatment (heparin or taurolidine). The primary outcomes were persistence and recurrence of the bacteraemia and Central Venous Access Device (CVAD) removal. Secondary outcomes included duration of antibiotic use, duration of hospitalization and side effects. Results: Data from eight HPN children experiencing 14 suspected CRI were analysed. Seven patients had proven CRIs by positive blood cultures. Four were treated with ELT and three with their standard flushing treatment. One CRI persisted in the control group. In one single patient, bacteraemia recurred three times within 24 weeks. This patient had been enrolled in both study arms. A CVAD removal was needed in one patient because of occlusion. Conclusions: This small study showed no additional efficacy of the use of ELT on cure rate or recurrences of CRIs compared to standard therapy in HPN treated children. There were also no differences in duration of hospitalization, the use of antibiotics or CVAD removal between both groups.展开更多
The aim of the study was to de-termine the oral health status and treatment needs of elderly residents of residential homes in Riyadh, Saudi Arabia. Methods: Among 129 elderly residents, 83 (51 males, and 32 females) ...The aim of the study was to de-termine the oral health status and treatment needs of elderly residents of residential homes in Riyadh, Saudi Arabia. Methods: Among 129 elderly residents, 83 (51 males, and 32 females) of them were interviewed and clini-cally examined according to WHO criteria by two calibrated dentists. Results: The mean age of the subjects was 72 ± 8.5. Male subjects had a higher smoking rate than females. Among elderly subjects below 74 years old, 20.8% had a functional dentition (> or = 20), while only 6.7% for those aged greater or equal to 75 years (p = 0.0004). Mean number of the sound teeth in all subjects was 6.7 ± 8.5. The mean number of DMFT was 18.6 ± 12.6. The missing component was the highest (16 ± 13) for both genders. The mean number of decayed roots was 2.75 ± 3.95 in males and 0.63 ± 1.96 in females. Overall, males had more sound and decayed teeth and less filled and missed teeth than females. There was no significant difference between males and females in periodontal problems except the calculus scores. The majority of subjects in need for tooth extraction were male subjects. With no gender difference 63% were in need for restorations, 40% needed upper and lower full dentures. Need for partial dentures was 38% upper and 48% lower. Conclusion: The oral health of the institutionalized elderly population in Saudi Arabia is generally poor and their treatment needs are high.展开更多
It is evident that matrix metalloproteinases (MMPs) are involved in the pathophysiology of different inflammatory skin diseases. In this pilot study, we investigated the ability of very high frequency ultrasound—freq...It is evident that matrix metalloproteinases (MMPs) are involved in the pathophysiology of different inflammatory skin diseases. In this pilot study, we investigated the ability of very high frequency ultrasound—frequencies of approximately 10 MHz—to modulate the activity of MMPs in the skin in inflammatory skin diseases such as acne and rosacea. It was shown that such waves can significantly improve the skin appearance in these diseases;however, the results are dependent on applied treatment schedule. The best results were obtained through the application of a super-fractionation strategy in the form of home treatments carried out twice daily.展开更多
TimeslipsTM is a group storytelling program that encourages creative expression among dementia patients without the pressure to recall the past. Analysis of the literature was conducted to determine the nine most rele...TimeslipsTM is a group storytelling program that encourages creative expression among dementia patients without the pressure to recall the past. Analysis of the literature was conducted to determine the nine most relevant agitation and anxiety scales most appropriate for use with Timeslips in nursing home patients with dementia, who experience agitation and anxiety. Qualitative assessment of the nine scales was conducted to identify six criteria to determine the most pertinent characteristics for implementation of Timeslips within this patient population: 1) validity/reliability, 2) observation period, 3) training required, 4) time to administer, 5) most appropriate administrator and 6) accessibility/cost. Utilizing these six criteria, quantitative assessment was conducted using the Analytical Hierarchical Process (AHP) to identify that the Overt Agitation Severity Scale (OASS) was optimal. IRB approvals have been attained to investigate use of the OASS with Timeslips in the nursing home setting for patients with dementia, who experience agitation and anxiety.展开更多
Five-year survival rate for patients with all cancers combined, in China, is only 30.9%, which is much lower than those in developed countries. The three main reasons for the low cancer curative rates in China include...Five-year survival rate for patients with all cancers combined, in China, is only 30.9%, which is much lower than those in developed countries. The three main reasons for the low cancer curative rates in China include differences in the spectrum of cancer types, in early detection rates, and in the percentage of cancer patients receiving standardized treatment between China and developed countries.The most important mechanism for improving the curative rate is to improve early detection rates of major cancers in China using novel and affordable technologies that can be operated at home by the patients themselves.This attempt could be helpful in setting up a practical example for other developing countries with limited medical resources and a limited number of healthcare practitioners.展开更多
Background: Category II tuberculosis (TB) patients (i.e. re-treatment TB patients) are at an increased risk for defaulting on treatment compared to Category I TB patients. Therefore, extra steps need to be taken to he...Background: Category II tuberculosis (TB) patients (i.e. re-treatment TB patients) are at an increased risk for defaulting on treatment compared to Category I TB patients. Therefore, extra steps need to be taken to help Category II TB patients follow through with their treatment. The goal of this study was to examine the effectiveness of three different types of interventions to help improve treatment success rates among Category II patients. Materials and Methods: Three different interventions that were implemented among Category II TB patients in the Bardhaman, Hugli, Malda and Murshidabad districts in West Bengal, India, were: 1) setting up group patient provider meetings (PPMs), 2) making home visits and reinforcing the message of full course of treatment, and 3) linking poor TB patients to social welfare schemes (SWSs) to incentivize them to complete treatment. Results: PPMs and SWSs improved treatment success rates among Category II patients. The treatment success rates for patients who received PPMs and patients who received SWSs were 94.2% and 90.7%, respectively, compared to the 74.5% treatment success rate of patients who received no intervention. The effectiveness of home visits, however, depended on the number of home visits the patient received. Conclusion: PPMs and SWSs improve treatment success among Category II TB patients and may easily be incorporated in Directly Observed Treatment, Short-Course programming as feasible ways. A conclusion regarding home visits, however, could not be drawn from this study.展开更多
文摘Water is an indispensable resource for life. In the district of Ahomadégbé in Benin, although most of the population has access to improved water sources, in their homes, residents consume poor water quality due to microbiological contamination during transport and storage. To identify necessary actions needed to improve household drinking water quality, the present study aims to analyze the knowledge, attitudes, and practices the district of Ahomadégbé’s population regarding household drinking water treatments methods. A study was conducted, where 377 residents were interviewed using an individual questionnaire and 82 participants were selected for eight focus groups to determine the population’s knowledge, attitudes, and practices. More than 65% of the district’s population knew some methods of water treatment at home. In practice, however, they lacked the knowledge to apply the different water treatment methods and only 6.1% of the population used at least one method of water treatment at home, even if it was not always adapted. The water treatment methods residents used were Alum (KAl(SO4)2·12 H2O, chemical decantation method), filtration on tissues, and disinfection by boiling. Ineffective home water treatment methods, such as oil and cresol were also used. The population is aware of water contamination during transport and storage. Unfortunately, most residents surveyed do not treat water before consumption, and those who treat it, use inappropriate methods. Thus, people must be made aware of the health benefits of using effective home water treatment methods and their correct use.
文摘Background: Catheter related bloodstream infections (CRIs) are a major cause of morbidity, mortality and prolonged hospitalization in pediatric patients with home parenteral nutrition (HPN). In recent years, new prophylactic and treatment options have been evaluated to reduce the incidence of CRIs and infection related catheter removals. In children, two retrospective studies have shown the efficacy of ethanol lock treatment (ELT) in reducing the incidence of CRIs in pediatric oncology patients. However, prospective data are missing. Our aim of the present study was to evaluate prospectively the effect of ELT on the cure and recurrence rate of CRIs, duration of hospitalization and antibiotic use in HPN pediatric patients. Methods: HPN children older than three months with a clinical suspicion of a CRI were included and randomised to ELT or standard flushing treatment (heparin or taurolidine). The primary outcomes were persistence and recurrence of the bacteraemia and Central Venous Access Device (CVAD) removal. Secondary outcomes included duration of antibiotic use, duration of hospitalization and side effects. Results: Data from eight HPN children experiencing 14 suspected CRI were analysed. Seven patients had proven CRIs by positive blood cultures. Four were treated with ELT and three with their standard flushing treatment. One CRI persisted in the control group. In one single patient, bacteraemia recurred three times within 24 weeks. This patient had been enrolled in both study arms. A CVAD removal was needed in one patient because of occlusion. Conclusions: This small study showed no additional efficacy of the use of ELT on cure rate or recurrences of CRIs compared to standard therapy in HPN treated children. There were also no differences in duration of hospitalization, the use of antibiotics or CVAD removal between both groups.
文摘The aim of the study was to de-termine the oral health status and treatment needs of elderly residents of residential homes in Riyadh, Saudi Arabia. Methods: Among 129 elderly residents, 83 (51 males, and 32 females) of them were interviewed and clini-cally examined according to WHO criteria by two calibrated dentists. Results: The mean age of the subjects was 72 ± 8.5. Male subjects had a higher smoking rate than females. Among elderly subjects below 74 years old, 20.8% had a functional dentition (> or = 20), while only 6.7% for those aged greater or equal to 75 years (p = 0.0004). Mean number of the sound teeth in all subjects was 6.7 ± 8.5. The mean number of DMFT was 18.6 ± 12.6. The missing component was the highest (16 ± 13) for both genders. The mean number of decayed roots was 2.75 ± 3.95 in males and 0.63 ± 1.96 in females. Overall, males had more sound and decayed teeth and less filled and missed teeth than females. There was no significant difference between males and females in periodontal problems except the calculus scores. The majority of subjects in need for tooth extraction were male subjects. With no gender difference 63% were in need for restorations, 40% needed upper and lower full dentures. Need for partial dentures was 38% upper and 48% lower. Conclusion: The oral health of the institutionalized elderly population in Saudi Arabia is generally poor and their treatment needs are high.
文摘It is evident that matrix metalloproteinases (MMPs) are involved in the pathophysiology of different inflammatory skin diseases. In this pilot study, we investigated the ability of very high frequency ultrasound—frequencies of approximately 10 MHz—to modulate the activity of MMPs in the skin in inflammatory skin diseases such as acne and rosacea. It was shown that such waves can significantly improve the skin appearance in these diseases;however, the results are dependent on applied treatment schedule. The best results were obtained through the application of a super-fractionation strategy in the form of home treatments carried out twice daily.
文摘TimeslipsTM is a group storytelling program that encourages creative expression among dementia patients without the pressure to recall the past. Analysis of the literature was conducted to determine the nine most relevant agitation and anxiety scales most appropriate for use with Timeslips in nursing home patients with dementia, who experience agitation and anxiety. Qualitative assessment of the nine scales was conducted to identify six criteria to determine the most pertinent characteristics for implementation of Timeslips within this patient population: 1) validity/reliability, 2) observation period, 3) training required, 4) time to administer, 5) most appropriate administrator and 6) accessibility/cost. Utilizing these six criteria, quantitative assessment was conducted using the Analytical Hierarchical Process (AHP) to identify that the Overt Agitation Severity Scale (OASS) was optimal. IRB approvals have been attained to investigate use of the OASS with Timeslips in the nursing home setting for patients with dementia, who experience agitation and anxiety.
基金supported by grants from the National Natural Science Foundation of China(No.81472386,No.81672872)the National High Technology Research and Development Program of China(863 Program)(No.2012AA02A501)+1 种基金the Science and Technology Planning Project of Guangdong Province,China(No.2014B020212017,No.20148050504004 and No.2015B050501005)the Provincial Natural Science Foundation of Guangdong,China(No.2016A030311011)
文摘Five-year survival rate for patients with all cancers combined, in China, is only 30.9%, which is much lower than those in developed countries. The three main reasons for the low cancer curative rates in China include differences in the spectrum of cancer types, in early detection rates, and in the percentage of cancer patients receiving standardized treatment between China and developed countries.The most important mechanism for improving the curative rate is to improve early detection rates of major cancers in China using novel and affordable technologies that can be operated at home by the patients themselves.This attempt could be helpful in setting up a practical example for other developing countries with limited medical resources and a limited number of healthcare practitioners.
文摘Background: Category II tuberculosis (TB) patients (i.e. re-treatment TB patients) are at an increased risk for defaulting on treatment compared to Category I TB patients. Therefore, extra steps need to be taken to help Category II TB patients follow through with their treatment. The goal of this study was to examine the effectiveness of three different types of interventions to help improve treatment success rates among Category II patients. Materials and Methods: Three different interventions that were implemented among Category II TB patients in the Bardhaman, Hugli, Malda and Murshidabad districts in West Bengal, India, were: 1) setting up group patient provider meetings (PPMs), 2) making home visits and reinforcing the message of full course of treatment, and 3) linking poor TB patients to social welfare schemes (SWSs) to incentivize them to complete treatment. Results: PPMs and SWSs improved treatment success rates among Category II patients. The treatment success rates for patients who received PPMs and patients who received SWSs were 94.2% and 90.7%, respectively, compared to the 74.5% treatment success rate of patients who received no intervention. The effectiveness of home visits, however, depended on the number of home visits the patient received. Conclusion: PPMs and SWSs improve treatment success among Category II TB patients and may easily be incorporated in Directly Observed Treatment, Short-Course programming as feasible ways. A conclusion regarding home visits, however, could not be drawn from this study.
