The mechanistic target of rapamycin(m TOR) is a serine/threonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regul...The mechanistic target of rapamycin(m TOR) is a serine/threonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regulates diverse aspects of neural development and function. Genetic mutations within the m TOR pathway lead to severe neurodevelopmental disorders, collectively known as “mTORopathies”(Crino, 2020). Dysfunctions of m TOR, including both its hyperactivation and hypoactivation, have also been implicated in a wide spectrum of other neurodevelopmental and neurodegenerative conditions, highlighting its importance in CNS health.展开更多
The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to ...The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to more than 30% of the world's population,predominantly in developing countries where per capita farmland and food supply are only 40% of those in developed nations(FAO 2018).Meeting the Zero Hunger target amid ongoing population growth in these regions requires a substantial increase in agricultural production while minimizing soil degradation and adverse ecological impacts.This challenge is shared by many countries across South Asia,Africa,and Central and South America.展开更多
Innovation and Development Policy,简称“IDP”,中文名:《创新与发展政策(英文)》,是由中国科学院主管,中国科学院科技战略咨询研究院、中国科学学与科技政策研究会共同主办,国内外发行(ISSN:2096-5141,CN:10-1513/D)的英文国际期刊...Innovation and Development Policy,简称“IDP”,中文名:《创新与发展政策(英文)》,是由中国科学院主管,中国科学院科技战略咨询研究院、中国科学学与科技政策研究会共同主办,国内外发行(ISSN:2096-5141,CN:10-1513/D)的英文国际期刊。目前期刊每年出版两期。已发表论文在期刊网站可以自由获取,http://idp-journal.casisd.cn/browse/al/al2019/。展开更多
This paper studies the structural response of high-speed train wipers under the combined action of complex flow fields and scraping actions.The stress concentration areas are determined through simulation analysis,and...This paper studies the structural response of high-speed train wipers under the combined action of complex flow fields and scraping actions.The stress concentration areas are determined through simulation analysis,and the stress and aerodynamic load measurement points are reasonably arranged accordingly.The actual measurement is carried out in combination with the operating conditions of the existing lines.The stress variations and spectral characteristics of the train under different speed levels(80,160,180,200 km/h),tunnel entry and exit,and scraper action conditions were compared and analyzed.The stress amplification factors under tunnel intersection and scraper action were obtained,providing boundary conditions for the design of wipers for highspeed s.The research results show that the maximum stress of the wiper structure obtained through simulation calculation is concentrated at the connection of the wiper arm.Structural stress increases with the rise of speed grade.The stress increases by 1.11 times when the tunnel meets.When the scraper operates,the stress on the scraper arm increases by 4.1–7.6 times.Due to the broadband excitation effect of the aerodynamic load,the spectral energy of the structure is relatively high at the natural frequency,which excites the natural mode of the wiper.展开更多
Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.You...Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.Young students,with their active and vibrant minds,represent the future and hope of standardization.展开更多
China is carving out a distinctive development path which features urban-rural integration.This approach has not only yielded tangible results domestically but also drawn the attention of other countries.
This paper proposes a passive control method to reduce peak values of slipstream and turbulent kinetic energy in a high-speed train wake by attaching vortex generators(VGs)onto the upper surface of the tail car.The im...This paper proposes a passive control method to reduce peak values of slipstream and turbulent kinetic energy in a high-speed train wake by attaching vortex generators(VGs)onto the upper surface of the tail car.The impact of the VGs is assessed through the improved delayed detached eddy simulations(IDDES)after validating predictions against previous experimental measurements and other numerical predictions for the base case.The simulations indicate that strategically installed VGs can reduce the average slipstream velocity(U slipstream)and the upper limit of slipstream velocity(U_(slipstream,max))by~17%and~15%,respectively,as well as moving the peaks downstream by approximately train height,thus reducing the danger posed by slipstream to waiting passengers and trackside workers.Analysis shows that the wake turbulent kinetic energy diminishes as the vortex generators decelerate the downwash flow and reduce shear production in the wake.It is also found that the presence of VGs significantly impacts the flow on the upper surface near the tail by modifying the unsteady trailing longitudinal vortices through the formation of additional counter-rotating longitudinal vortices from the VGs.These latter vortices prevent the merging of vortical airflow around the trailing nose tip,which is otherwise induced by the longitudinal vortex of the train.They also reduce vortex intensity through cross-annihilation and cross diffusion as the wake advects downstream,limiting outwards advection through interaction with the image pair,and contributing to a decrease in the peak slipstream value.The method proposed offers a simple approach to wake control leading to significant slipstream benefits.展开更多
The axle box bearings of high-speed trains often operate in extremely harsh environments,bearing loads from different directions.Long-term operation and frequent changes in working conditions can easily lead to axle b...The axle box bearings of high-speed trains often operate in extremely harsh environments,bearing loads from different directions.Long-term operation and frequent changes in working conditions can easily lead to axle box bearing failures.Therefore,it is extremely important to study the mechanism of axle box bearings.Firstly,the medium of thermal deformation establishes a coupling relationship between the system dynamics model and the thermal grid model,and then obtains the thermal force coupling model of the high-speed train axle box bearing.The coupling model is validated from the perspectives of system dynamics response and temperature response,proving its effectiveness in system dynamics response and temperature characteristic response.Comparing the coupling model with the dynamics model,it is found that thermal deformation complicates the dynamic re-sponse.Finally,using the Lundberg-Palmgren(L-P)bearing fatigue calculation method and damage accumu-lation theory,the bearing fatigue life is calculated,and it is found that thermal deformation deteriorates the bearing operating environment,reducing the bearing fatigue life.Finally,by comparing the bearing fatigue life under different working conditions,it is concluded that the faster the vehicle speed,the greater the load,and the smaller the initial radial clearance of the bearing,the fatigue life of the bearing is reduced.The shorter the lifespan.展开更多
Research on high-speed railways is a relatively new yet highly significant field in Vietnam.Among its key components,train control signaling plays a critical role,as it directly affects various interconnected systems,...Research on high-speed railways is a relatively new yet highly significant field in Vietnam.Among its key components,train control signaling plays a critical role,as it directly affects various interconnected systems,including infrastructure,traction power supply,operational planning,and overall railway safety.This article focuses on evaluating the capacity of the line based on the types of signals suitable for high-speed railways that have been effectively implemented in several European countries and successfully adapted in China.The research and simulation are conducted using MATLAB software,a reliable and widely adopted tool in the scientific community.The findings demonstrate that under normal conditions,the European Railway Traffic Management System/European Train Control System(ERTMS/ETCS)Level 2 signaling can support up to 23.7485 trains/hour/direction.Meanwhile,ERTMS/ETCS Level 3 with full moving block can accommodate up to 30.8735 trains/hour/direction,and ERTMS/ETCS Level 3 with fixed virtual blocks up to 29.4694 trains/hour/direction.In emergency scenarios,ERTMS/ETCS Level 3 with full moving block reduces headway by 33.27%compared to CTCS Level 3,while ERTMS/ETCS Level 3 with fixed virtual blocks achieves a 28.78%reduction.Overall,the ERTMS/ETCS Level 3 emerges as a state-of-the-art signaling technology offering high capacity and operational efficiency,and is recommended as a forward-looking solution for future implementation in Vietnam.展开更多
County economies form a distinctive,integrated regional economic structure.Their growth is shaped by specific social and historical conditions and,in turn,influences many aspects of wider economic and social developme...County economies form a distinctive,integrated regional economic structure.Their growth is shaped by specific social and historical conditions and,in turn,influences many aspects of wider economic and social development.In China's modernization process,they have always played a vital role.The 2024 Central Economic Work Conference placed strong emphasis on vigorously developing county economies.展开更多
As China's high-speed railway technology advances,high-speed trains have emerged as a pivotal mode of transportation,instrumental in facilitating passenger and freight mobility while fostering robust regional eco-...As China's high-speed railway technology advances,high-speed trains have emerged as a pivotal mode of transportation,instrumental in facilitating passenger and freight mobility while fostering robust regional eco-nomic and trade interactions.Nonetheless,the safety of train operations remains a paramount concern,prompting extensive research into the dynamic behavior of critical components,which is essential to ensuring seamless and secure transportation services.This article commences by comprehensively reviewing the current landscape and evolutionary trajectory of dynamic model analysis for both traditional bearings and axle box bearings.Emphasis is placed on elucidating the profound influence of diverse bearing fault types on the system's kinematic state,alongside delving into the research methodologies employed in developing multi-physics field coupling models.Subsequently,it expounds on the content of investigations focusing on various wheel and track impairments,grounded in the dynamic modeling of the bearing vehicle coupling system.Concurrently,the intricate interplay between wheel-rail excitation and axle box bearing faults on the system's performance is elucidated.Concludingly,the article underscores the inadequacy of current multi-source fault diagnosis meth-odologies in tackling the intricacies of complex train operating environments,thereby highlighting its sig-nificance as a pressing and vital research agenda for the future.展开更多
1.Background The United Nations(UN)2030 Agenda for Sustainable Development,adopted in 2015,established the Sustainable Development Goals(SDGs)as a comprehensive framework to address global challenges through interconn...1.Background The United Nations(UN)2030 Agenda for Sustainable Development,adopted in 2015,established the Sustainable Development Goals(SDGs)as a comprehensive framework to address global challenges through interconnected social,economic,and environmental targets.展开更多
To advance intelligent construction,standards must come first.The Ministry of Housing and Urban-Rural Development has issued the List for Replicable Experience and Practices for Developing Intelligent Construction fou...To advance intelligent construction,standards must come first.The Ministry of Housing and Urban-Rural Development has issued the List for Replicable Experience and Practices for Developing Intelligent Construction four times successively and the Technical Guidelines for Intelligent Construction(Trial).展开更多
China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have alwa...China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have always been a priority in national development.At its fourth plenary session held in October 2025,the 20th Central Committee of the Communist Party of China(CPC)once again emphasized the need to accelerate agricultural and rural modernization,and advance all-around rural revitalization over the next five years.展开更多
The spatial offset of bridge has a significant impact on the safety,comfort,and durability of high-speed railway(HSR)operations,so it is crucial to rapidly and effectively detect the spatial offset of operational HSR ...The spatial offset of bridge has a significant impact on the safety,comfort,and durability of high-speed railway(HSR)operations,so it is crucial to rapidly and effectively detect the spatial offset of operational HSR bridges.Drive-by monitoring of bridge uneven settlement demonstrates significant potential due to its practicality,cost-effectiveness,and efficiency.However,existing drive-by methods for detecting bridge offset have limitations such as reliance on a single data source,low detection accuracy,and the inability to identify lateral deformations of bridges.This paper proposes a novel drive-by inspection method for spatial offset of HSR bridge based on multi-source data fusion of comprehensive inspection train.Firstly,dung beetle optimizer-variational mode decomposition was employed to achieve adaptive decomposition of non-stationary dynamic signals,and explore the hidden temporal relationships in the data.Subsequently,a long short-term memory neural network was developed to achieve feature fusion of multi-source signal and accurate prediction of spatial settlement of HSR bridge.A dataset of track irregularities and CRH380A high-speed train responses was generated using a 3D train-track-bridge interaction model,and the accuracy and effectiveness of the proposed hybrid deep learning model were numerically validated.Finally,the reliability of the proposed drive-by inspection method was further validated by analyzing the actual measurement data obtained from comprehensive inspection train.The research findings indicate that the proposed approach enables rapid and accurate detection of spatial offset in HSR bridge,ensuring the long-term operational safety of HSR bridges.展开更多
Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables th...Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs.展开更多
Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications i...Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.展开更多
Railway noise barriers are an essential piece of infrastructure for reducing noise propagation.However,these barriers experience aerodynamic loads generated by high-speed trains,leading to dynamic effects that may com...Railway noise barriers are an essential piece of infrastructure for reducing noise propagation.However,these barriers experience aerodynamic loads generated by high-speed trains,leading to dynamic effects that may compromise their fatigue capacity.The most common structural design for railway noise barriers consists of vertical configurations of posts and panels.However,there have been few dynamic analyses of steel post/wood panel noise barriers under train-induced aerodynamic loads.This study used dynamic finite element analysis to assess the dynamic behavior of such noise barriers.Analysis of a 40-m-long noise barrier model and a triangular simplified load model,the latter of which effectively represented the detailed aerodynamic load,were first used to establish the model and input of the moving load during dynamic simulation.Then,the effects of different parameters on the dynamic response of the noise barrier were evaluated,including the damping ratio,the profile of the steel post,the span length of the panel,the barrier height,and the train speed.Gray relational analysis indicated that barrier height exhibited the highest correlations with the dynamic responses,followed by train speed,post profile,span length,and damping ratio.A reduction in the natural frequency and an increase in the train speed result in a higher peak response and more pronounced fluctuations between the nose and tail waves.The dynamic amplification factor(DAF)was found to be related to both the natural frequency and train speed.A model was proposed showing that the DAF significantly increases as the square of the natural frequency decreases and the cube of the train speed rises.展开更多
The 20th Communist Party of China(CPC)Central Committee held its fourth plenary session in Beijing on October 20-23.The plenary session's central task was to deliberate on the framework of the country's next n...The 20th Communist Party of China(CPC)Central Committee held its fourth plenary session in Beijing on October 20-23.The plenary session's central task was to deliberate on the framework of the country's next national development roadmap:the 15th Five-Year Plan(2026-2030).Every five-year plan is important but this one arrives at a truly pivotal moment in terms of China's development trajectory and the global environment.展开更多
基金financially supported by the Central Government Guiding Local Science and Technology Development Fund of Henan Province(Z20241471091)the Independent R&D Funds of State Key Laboratory of Advanced Metallurgy(41624025).
基金supported by grants from Simons Foundation (SFARI 479754),CIHR (PJT-180565)the Scottish Rite Charitable Foundation of Canada (to YL)funding from the Canada Research Chairs program。
文摘The mechanistic target of rapamycin(m TOR) is a serine/threonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regulates diverse aspects of neural development and function. Genetic mutations within the m TOR pathway lead to severe neurodevelopmental disorders, collectively known as “mTORopathies”(Crino, 2020). Dysfunctions of m TOR, including both its hyperactivation and hypoactivation, have also been implicated in a wide spectrum of other neurodevelopmental and neurodegenerative conditions, highlighting its importance in CNS health.
文摘The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to more than 30% of the world's population,predominantly in developing countries where per capita farmland and food supply are only 40% of those in developed nations(FAO 2018).Meeting the Zero Hunger target amid ongoing population growth in these regions requires a substantial increase in agricultural production while minimizing soil degradation and adverse ecological impacts.This challenge is shared by many countries across South Asia,Africa,and Central and South America.
文摘Innovation and Development Policy,简称“IDP”,中文名:《创新与发展政策(英文)》,是由中国科学院主管,中国科学院科技战略咨询研究院、中国科学学与科技政策研究会共同主办,国内外发行(ISSN:2096-5141,CN:10-1513/D)的英文国际期刊。目前期刊每年出版两期。已发表论文在期刊网站可以自由获取,http://idp-journal.casisd.cn/browse/al/al2019/。
文摘This paper studies the structural response of high-speed train wipers under the combined action of complex flow fields and scraping actions.The stress concentration areas are determined through simulation analysis,and the stress and aerodynamic load measurement points are reasonably arranged accordingly.The actual measurement is carried out in combination with the operating conditions of the existing lines.The stress variations and spectral characteristics of the train under different speed levels(80,160,180,200 km/h),tunnel entry and exit,and scraper action conditions were compared and analyzed.The stress amplification factors under tunnel intersection and scraper action were obtained,providing boundary conditions for the design of wipers for highspeed s.The research results show that the maximum stress of the wiper structure obtained through simulation calculation is concentrated at the connection of the wiper arm.Structural stress increases with the rise of speed grade.The stress increases by 1.11 times when the tunnel meets.When the scraper operates,the stress on the scraper arm increases by 4.1–7.6 times.Due to the broadband excitation effect of the aerodynamic load,the spectral energy of the structure is relatively high at the natural frequency,which excites the natural mode of the wiper.
文摘Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.Young students,with their active and vibrant minds,represent the future and hope of standardization.
文摘China is carving out a distinctive development path which features urban-rural integration.This approach has not only yielded tangible results domestically but also drawn the attention of other countries.
基金Project(52372370)supported by the National Natural Science Foundation of ChinaProject(2023ZZTS0379)supported by the Graduate Student Independent Innovation Project of Central South University,ChinaProject(202206370058)supported by the China Scholarship Council。
文摘This paper proposes a passive control method to reduce peak values of slipstream and turbulent kinetic energy in a high-speed train wake by attaching vortex generators(VGs)onto the upper surface of the tail car.The impact of the VGs is assessed through the improved delayed detached eddy simulations(IDDES)after validating predictions against previous experimental measurements and other numerical predictions for the base case.The simulations indicate that strategically installed VGs can reduce the average slipstream velocity(U slipstream)and the upper limit of slipstream velocity(U_(slipstream,max))by~17%and~15%,respectively,as well as moving the peaks downstream by approximately train height,thus reducing the danger posed by slipstream to waiting passengers and trackside workers.Analysis shows that the wake turbulent kinetic energy diminishes as the vortex generators decelerate the downwash flow and reduce shear production in the wake.It is also found that the presence of VGs significantly impacts the flow on the upper surface near the tail by modifying the unsteady trailing longitudinal vortices through the formation of additional counter-rotating longitudinal vortices from the VGs.These latter vortices prevent the merging of vortical airflow around the trailing nose tip,which is otherwise induced by the longitudinal vortex of the train.They also reduce vortex intensity through cross-annihilation and cross diffusion as the wake advects downstream,limiting outwards advection through interaction with the image pair,and contributing to a decrease in the peak slipstream value.The method proposed offers a simple approach to wake control leading to significant slipstream benefits.
基金Supported by the National Natural Science Foundation of China(Grant Nos.12393780,12032017,12302067)College Education Scientific Research Project of Hebei Province(Grant No.JZX2024006)Hebei Provincial S&T Program(Grant No.21567622 H).
文摘The axle box bearings of high-speed trains often operate in extremely harsh environments,bearing loads from different directions.Long-term operation and frequent changes in working conditions can easily lead to axle box bearing failures.Therefore,it is extremely important to study the mechanism of axle box bearings.Firstly,the medium of thermal deformation establishes a coupling relationship between the system dynamics model and the thermal grid model,and then obtains the thermal force coupling model of the high-speed train axle box bearing.The coupling model is validated from the perspectives of system dynamics response and temperature response,proving its effectiveness in system dynamics response and temperature characteristic response.Comparing the coupling model with the dynamics model,it is found that thermal deformation complicates the dynamic re-sponse.Finally,using the Lundberg-Palmgren(L-P)bearing fatigue calculation method and damage accumu-lation theory,the bearing fatigue life is calculated,and it is found that thermal deformation deteriorates the bearing operating environment,reducing the bearing fatigue life.Finally,by comparing the bearing fatigue life under different working conditions,it is concluded that the faster the vehicle speed,the greater the load,and the smaller the initial radial clearance of the bearing,the fatigue life of the bearing is reduced.The shorter the lifespan.
文摘Research on high-speed railways is a relatively new yet highly significant field in Vietnam.Among its key components,train control signaling plays a critical role,as it directly affects various interconnected systems,including infrastructure,traction power supply,operational planning,and overall railway safety.This article focuses on evaluating the capacity of the line based on the types of signals suitable for high-speed railways that have been effectively implemented in several European countries and successfully adapted in China.The research and simulation are conducted using MATLAB software,a reliable and widely adopted tool in the scientific community.The findings demonstrate that under normal conditions,the European Railway Traffic Management System/European Train Control System(ERTMS/ETCS)Level 2 signaling can support up to 23.7485 trains/hour/direction.Meanwhile,ERTMS/ETCS Level 3 with full moving block can accommodate up to 30.8735 trains/hour/direction,and ERTMS/ETCS Level 3 with fixed virtual blocks up to 29.4694 trains/hour/direction.In emergency scenarios,ERTMS/ETCS Level 3 with full moving block reduces headway by 33.27%compared to CTCS Level 3,while ERTMS/ETCS Level 3 with fixed virtual blocks achieves a 28.78%reduction.Overall,the ERTMS/ETCS Level 3 emerges as a state-of-the-art signaling technology offering high capacity and operational efficiency,and is recommended as a forward-looking solution for future implementation in Vietnam.
文摘County economies form a distinctive,integrated regional economic structure.Their growth is shaped by specific social and historical conditions and,in turn,influences many aspects of wider economic and social development.In China's modernization process,they have always played a vital role.The 2024 Central Economic Work Conference placed strong emphasis on vigorously developing county economies.
基金Supported by the National Natural Science Foundation of China(Grant Nos.12393783,12302067,12172235,52072249)Joint Funds of the National Natural Science Foundation of China(Grant No.U24A2003)+3 种基金College Education Scientific Research Project of Hebei Province(Grant No.JZX2024006)Central Guiding Local Scientific and Technological Development Funding Project(Grant No.246Z2206G)the Key Research Project of China State Railway Group Co.,Ltd.(Grant No.N2024T009)S&T Program of Hebei(Grant No.21567622H).
文摘As China's high-speed railway technology advances,high-speed trains have emerged as a pivotal mode of transportation,instrumental in facilitating passenger and freight mobility while fostering robust regional eco-nomic and trade interactions.Nonetheless,the safety of train operations remains a paramount concern,prompting extensive research into the dynamic behavior of critical components,which is essential to ensuring seamless and secure transportation services.This article commences by comprehensively reviewing the current landscape and evolutionary trajectory of dynamic model analysis for both traditional bearings and axle box bearings.Emphasis is placed on elucidating the profound influence of diverse bearing fault types on the system's kinematic state,alongside delving into the research methodologies employed in developing multi-physics field coupling models.Subsequently,it expounds on the content of investigations focusing on various wheel and track impairments,grounded in the dynamic modeling of the bearing vehicle coupling system.Concurrently,the intricate interplay between wheel-rail excitation and axle box bearing faults on the system's performance is elucidated.Concludingly,the article underscores the inadequacy of current multi-source fault diagnosis meth-odologies in tackling the intricacies of complex train operating environments,thereby highlighting its sig-nificance as a pressing and vital research agenda for the future.
文摘1.Background The United Nations(UN)2030 Agenda for Sustainable Development,adopted in 2015,established the Sustainable Development Goals(SDGs)as a comprehensive framework to address global challenges through interconnected social,economic,and environmental targets.
文摘To advance intelligent construction,standards must come first.The Ministry of Housing and Urban-Rural Development has issued the List for Replicable Experience and Practices for Developing Intelligent Construction four times successively and the Technical Guidelines for Intelligent Construction(Trial).
文摘China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have always been a priority in national development.At its fourth plenary session held in October 2025,the 20th Central Committee of the Communist Party of China(CPC)once again emphasized the need to accelerate agricultural and rural modernization,and advance all-around rural revitalization over the next five years.
基金sponsored by the National Natural Science Foundation of China(Grant No.52178100).
文摘The spatial offset of bridge has a significant impact on the safety,comfort,and durability of high-speed railway(HSR)operations,so it is crucial to rapidly and effectively detect the spatial offset of operational HSR bridges.Drive-by monitoring of bridge uneven settlement demonstrates significant potential due to its practicality,cost-effectiveness,and efficiency.However,existing drive-by methods for detecting bridge offset have limitations such as reliance on a single data source,low detection accuracy,and the inability to identify lateral deformations of bridges.This paper proposes a novel drive-by inspection method for spatial offset of HSR bridge based on multi-source data fusion of comprehensive inspection train.Firstly,dung beetle optimizer-variational mode decomposition was employed to achieve adaptive decomposition of non-stationary dynamic signals,and explore the hidden temporal relationships in the data.Subsequently,a long short-term memory neural network was developed to achieve feature fusion of multi-source signal and accurate prediction of spatial settlement of HSR bridge.A dataset of track irregularities and CRH380A high-speed train responses was generated using a 3D train-track-bridge interaction model,and the accuracy and effectiveness of the proposed hybrid deep learning model were numerically validated.Finally,the reliability of the proposed drive-by inspection method was further validated by analyzing the actual measurement data obtained from comprehensive inspection train.The research findings indicate that the proposed approach enables rapid and accurate detection of spatial offset in HSR bridge,ensuring the long-term operational safety of HSR bridges.
文摘Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs.
基金supported by the National Natural Science Foundation of China(Grant No.32160172)the Key Science-Technology Project of Inner Mongolia(2023KYPT0010)+1 种基金the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Grant No.2025QN03006)the 2023 Inner Mongolia Public Institution High-Level Talent Introduction Scientific Research Support Project.
文摘Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.
基金financially supported by the Swedish Transport Administration(Trafikverket)through the“Excellence Area 4”and FOI-BBT program(Grant Nos.BBT-2019-022 and BBT-TRV 2024/132497).
文摘Railway noise barriers are an essential piece of infrastructure for reducing noise propagation.However,these barriers experience aerodynamic loads generated by high-speed trains,leading to dynamic effects that may compromise their fatigue capacity.The most common structural design for railway noise barriers consists of vertical configurations of posts and panels.However,there have been few dynamic analyses of steel post/wood panel noise barriers under train-induced aerodynamic loads.This study used dynamic finite element analysis to assess the dynamic behavior of such noise barriers.Analysis of a 40-m-long noise barrier model and a triangular simplified load model,the latter of which effectively represented the detailed aerodynamic load,were first used to establish the model and input of the moving load during dynamic simulation.Then,the effects of different parameters on the dynamic response of the noise barrier were evaluated,including the damping ratio,the profile of the steel post,the span length of the panel,the barrier height,and the train speed.Gray relational analysis indicated that barrier height exhibited the highest correlations with the dynamic responses,followed by train speed,post profile,span length,and damping ratio.A reduction in the natural frequency and an increase in the train speed result in a higher peak response and more pronounced fluctuations between the nose and tail waves.The dynamic amplification factor(DAF)was found to be related to both the natural frequency and train speed.A model was proposed showing that the DAF significantly increases as the square of the natural frequency decreases and the cube of the train speed rises.
文摘The 20th Communist Party of China(CPC)Central Committee held its fourth plenary session in Beijing on October 20-23.The plenary session's central task was to deliberate on the framework of the country's next national development roadmap:the 15th Five-Year Plan(2026-2030).Every five-year plan is important but this one arrives at a truly pivotal moment in terms of China's development trajectory and the global environment.
