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Developing High-Precision Maps for Automated Driving in China:Legal Obstacles and the Way to Overcome Them 被引量:2
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作者 ZHANG Taolue TU Huizhao QIU Wei 《Journal of Shanghai Jiaotong university(Science)》 EI 2021年第5期658-669,共12页
A high-precision map(HPM)is the key infrastructure to realizing the function of automated driving(AD)and ensuring its safety.However,the current laws and regulations on HPMs in China can lead to serious legal complian... A high-precision map(HPM)is the key infrastructure to realizing the function of automated driving(AD)and ensuring its safety.However,the current laws and regulations on HPMs in China can lead to serious legal compliance problems.Thus,proper measures should be taken to remove these barriers.Starting with a complete view of the current legal obstacles to HPMs in China,this study first explains why these legal obstacles exist and the types of legal interests they are trying to protect.It then analyzes whether new technology could be used as an alternative to resolve these concerns.Factors such as national security,AD industry needs,and personal data protection,as well as the flexibility of applying technology,are discussed and analyzed hierarchically for this purpose.This study proposes that China should adhere to national security and AD industry development,pass new technical regulations that redefine the scope of national security regarding geographic information in the field of HPMs,and establish a national platform under the guidance and monitoring of the government to integrate scattered resources and promote the development of HPMs via crowdsourcing.Regarding the legal obstacles with higher technical plasticity,priority should be given to technical solutions such as“available but invisible”technology.Compared with the previous research,this study reveals the current legal barriers in China that have different levels of relevance to national security and different technical plasticity.It also proposes original measures to remove them,such as coordinating national security with the development of the AD industry,reshaping the boundary of national security and industrial interests,and giving priority to technical solutions for legal barriers that have strong technical plasticity. 展开更多
关键词 automated driving(AD) navigation electronic map(NEM) high-precision map(HPM) surveying and mapping national security “available but invisible”technology
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Data Logic Structure and Key Technologies on Intelligent High-precision Map 被引量:17
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作者 Jingnan LIU Jiao ZHAN +2 位作者 Chi GUO Tingting LEI Ying LI 《Journal of Geodesy and Geoinformation Science》 2020年第3期1-17,共17页
Taking autonomous driving and driverless as the research object,we discuss and define intelligent high-precision map.Intelligent high-precision map is considered as a key link of future travel,a carrier of real-time p... Taking autonomous driving and driverless as the research object,we discuss and define intelligent high-precision map.Intelligent high-precision map is considered as a key link of future travel,a carrier of real-time perception of traffic resources in the entire space-time range,and the criterion for the operation and control of the whole process of the vehicle.As a new form of map,it has distinctive features in terms of cartography theory and application requirements compared with traditional navigation electronic maps.Thus,it is necessary to analyze and discuss its key features and problems to promote the development of research and application of intelligent high-precision map.Accordingly,we propose an information transmission model based on the cartography theory and combine the wheeled robot’s control flow in practical application.Next,we put forward the data logic structure of intelligent high-precision map,and analyze its application in autonomous driving.Then,we summarize the computing mode of“Crowdsourcing+Edge-Cloud Collaborative Computing”,and carry out key technical analysis on how to improve the quality of crowdsourced data.We also analyze the effective application scenarios of intelligent high-precision map in the future.Finally,we present some thoughts and suggestions for the future development of this field. 展开更多
关键词 intelligent high-precision map information transmission model data logic structure user model computing mode edge-cloud collaboration
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High-precision classification of benthic habitat sediments in shallow waters of islands by multi-source data
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作者 Qiuhua TANG Ningning LI +4 位作者 Yujie ZHANG Zhipeng DONG Yongling ZHENG Jingjing BAO Jingyu ZHANG 《Journal of Oceanology and Limnology》 2026年第1期99-108,共10页
Benthic habitat mapping is an emerging discipline in the international marine field in recent years,providing an effective tool for marine spatial planning,marine ecological management,and decision-making applications... Benthic habitat mapping is an emerging discipline in the international marine field in recent years,providing an effective tool for marine spatial planning,marine ecological management,and decision-making applications.Seabed sediment classification is one of the main contents of seabed habitat mapping.In response to the impact of remote sensing imaging quality and the limitations of acoustic measurement range,where a single data source does not fully reflect the substrate type,we proposed a high-precision seabed habitat sediment classification method that integrates data from multiple sources.Based on WorldView-2 multi-spectral remote sensing image data and multibeam bathymetry data,constructed a random forests(RF)classifier with optimal feature selection.A seabed sediment classification experiment integrating optical remote sensing and acoustic remote sensing data was carried out in the shallow water area of Wuzhizhou Island,Hainan,South China.Different seabed sediment types,such as sand,seagrass,and coral reefs were effectively identified,with an overall classification accuracy of 92%.Experimental results show that RF matrix optimized by fusing multi-source remote sensing data for feature selection were better than the classification results of simple combinations of data sources,which improved the accuracy of seabed sediment classification.Therefore,the method proposed in this paper can be effectively applied to high-precision seabed sediment classification and habitat mapping around islands and reefs. 展开更多
关键词 Wuzhizhou Island marine remote sensing coastal mapping multi-spectral remote sensing shallow water reef seabed sediment classification benthic habitat mapping multi-source data fusion random forest(RF)
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基于Maps统计分析的冶金尘泥还原焙烧机理
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作者 李强 陈铁军 +3 位作者 陈佳乐 黄宇平 李圣辉 李奇勇 《钢铁》 北大核心 2026年第1期188-200,共13页
冶金尘泥的转底炉处理工艺是目前钢铁行业采用的主要处置工艺,但在实际生产过程中经常出现还原焙烧不均匀的问题。利用微观扫描电子显微镜(scanning electron microscopy,SEM)分析结合宏观Maps统计分析,对冶金尘泥还原焙烧的不均匀性进... 冶金尘泥的转底炉处理工艺是目前钢铁行业采用的主要处置工艺,但在实际生产过程中经常出现还原焙烧不均匀的问题。利用微观扫描电子显微镜(scanning electron microscopy,SEM)分析结合宏观Maps统计分析,对冶金尘泥还原焙烧的不均匀性进行详细的可视化、数据化分析。研究结果表明,冶金尘泥在焙烧温度为1250℃、焙烧时间为15 min的条件下,熟球金属化率达到89.04%、脱锌率达到81.66%、抗压强度达到3.03 kN,熟球金属化率和脱锌率会随着焙烧温度提高和焙烧时间延长而进一步提高,但熟球抗压强度在焙烧时间过长时反而逐渐降低;熟球Maps统计分析表明,提高焙烧温度更有利于提高熟球外圈和下部的还原程度,而延长焙烧时间也更有利于提高熟球下部还原程度,但对熟球内部和外圈还原程度的提升作用比较相似;同时,提高焙烧温度也更有利于提升熟球下部的致密化程度,降低熟球上、下孔隙结构的不均匀性,进而显著提高熟球整体抗压强度;但焙烧时间过长会导致熟球中小孔隙融合为大孔隙,反而降低熟球抗压强度。此外,熟球中硅酸盐(渣相)和浮氏体(FexO)更容易破裂,而金属铁(Fe)可延缓裂纹蔓延,因而,适当提高熟球金属化率、降低硅酸盐(渣相)含量也有利于提高其抗压强度。基于Maps统计分析探究了冶金尘泥还原焙烧过程中物相及孔隙的变化规律,分析结果可以为转底炉工艺处理冶金尘泥的生产实践提供指导和建议。 展开更多
关键词 冶金尘泥 焙烧温度 焙烧时间 maps统计分析 金属化率 抗压强度 转底炉 熟球
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磁共振集合序列技术替代T_(2) Mapping成像对成人膝关节软骨定量分析价值
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作者 武金龙 杨慧 《实用医学影像杂志》 2026年第1期32-35,共4页
目的分析使用磁共振集合序列(MAGIC)技术替代传统T_(2) Mapping成像定量分析成人膝关节关节软骨的临床价值。方法收集本院体检受试者36例,分为3组21~30岁,11例;31~40岁,10例;41~50岁,15例,分别行MAGIC和T_(2) Mapping扫描,比较软骨MAGIC... 目的分析使用磁共振集合序列(MAGIC)技术替代传统T_(2) Mapping成像定量分析成人膝关节关节软骨的临床价值。方法收集本院体检受试者36例,分为3组21~30岁,11例;31~40岁,10例;41~50岁,15例,分别行MAGIC和T_(2) Mapping扫描,比较软骨MAGIC T_(2)值与T_(2) Mapping T_(2)值是否存在差异。比较各年龄段胫骨内侧平台软骨、胫骨外侧平台软骨、股骨内侧髁软骨、股骨外侧髁软骨、髌骨表面软骨差异。结果MAGIC与T_(2) Mapping 2种方法分别对膝关节的不同部位关节软骨定量T_(2)值分析,2种方法对比差异无统计学意义(P>0.05)。41~50岁与21~30岁关节软骨厚度差异有统计学意义。利用MAGIC技术发现41~50岁与21~30岁各部位关节软骨T_(2)测值差异有统计学意义(P<0.05)。结论MAGIC技术能代替传统T_(2) Mapping成像方法定量分析成人膝关节软骨。 展开更多
关键词 膝关节 软骨 成人 磁共振集合序列 T_(2)mapping 定量分析
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基于Connectivity Map的药物重定位评价维拉帕米作为治疗帕金森病的药物
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作者 新吉乐 刘晶 +6 位作者 张欣翼 郭家缘 韩文卓 孙怡馨 赵乐 冯卫生 郑晓珂 《中国临床药理学与治疗学》 北大核心 2026年第1期14-27,共14页
目的:筛选调控帕金森病(Parkinson's disease,PD)发病关键基因及相关转录因子表达的小分子化合物。方法:分析PD患者的基因表达谱数据,筛选PD发病关键基因及转录因子。Connectivity Map(CMap)筛选可调控转录因子表达的小分子药物,并... 目的:筛选调控帕金森病(Parkinson's disease,PD)发病关键基因及相关转录因子表达的小分子化合物。方法:分析PD患者的基因表达谱数据,筛选PD发病关键基因及转录因子。Connectivity Map(CMap)筛选可调控转录因子表达的小分子药物,并在6-羟基多巴胺(6-OHDA)诱导损伤的PC12细胞和PD小鼠模型评价其PD治疗作用。结果:维拉帕米(verapamil,Ver)为潜在的候选药物。Ver对6-OHDA损伤的PC12细胞具有保护作用,同时对6-OHDA诱导的PAX5、LEF1、MTF1、IKZF3和SP140等转录因子,以及ITGA6、CDH1、CD40、ESR1、SMAD3、CXCR4等PD发病基因的表达具有调控作用。PD模型小鼠中,Ver可对α-突触核蛋白(α-Syn)表达有一定抑制作用,但对上述PD发病基因及其转录因子和调控作用较弱。结论:Ver对PD的治疗作用部分依赖于对PD发病基因及其相关转录因子的调控作用。 展开更多
关键词 帕金森病 转录因子 Connectivity map 维拉帕米 6-羟基多巴胺
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Native T1 mapping值显著延长心脏纤维瘤一例
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作者 文涛 张辉 +3 位作者 甘铁军 胡万均 李世兰 张静 《磁共振成像》 北大核心 2026年第1期120-122,共3页
本研究为回顾性研究,遵守《赫尔辛基宣言》,并经兰州大学第二医院伦理委员会审核批准,免除受试者知情同意,批准文号:2025A-547。患儿,女,2月8天,因“发现心脏肿瘤2月”于2024年11月就诊于我院,患儿于2个月前出生后外院检查提示左心室肿... 本研究为回顾性研究,遵守《赫尔辛基宣言》,并经兰州大学第二医院伦理委员会审核批准,免除受试者知情同意,批准文号:2025A-547。患儿,女,2月8天,因“发现心脏肿瘤2月”于2024年11月就诊于我院,患儿于2个月前出生后外院检查提示左心室肿瘤,未予特殊诊治,现为进一步明确诊治收住我院心脏外科。患儿足月(38+6周)、顺产、无心脏肿瘤家族史。查体:心前区无隆起,心界不大,心音有力、律齐,胸骨左缘第2~3肋间可闻及3/6及吹风样杂音,静息血氧饱和度100%。 展开更多
关键词 心脏肿瘤 心脏纤维瘤 多模态磁共振成像 心脏磁共振 Native T1 mapping
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T2 Mapping联合DWI序列评估直肠癌脉管侵犯价值研究
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作者 李茜玮 陈安良 +2 位作者 王楠 林良杰 刘爱连 《中国CT和MRI杂志》 2026年第1期149-152,共4页
目的探讨T2 mapping与DWI序列预测直肠癌脉管侵犯的价值。方法回顾性分析经本院行3.0T MRI扫描且经术后病理证实的直肠癌脉管侵犯13例,脉管非侵犯20例,2名观察者分别于瘤体显示最大层面参考增强动脉期图像及DWI图像于T2 mapping及ADC图... 目的探讨T2 mapping与DWI序列预测直肠癌脉管侵犯的价值。方法回顾性分析经本院行3.0T MRI扫描且经术后病理证实的直肠癌脉管侵犯13例,脉管非侵犯20例,2名观察者分别于瘤体显示最大层面参考增强动脉期图像及DWI图像于T2 mapping及ADC图像上测量病灶T2值及ADC值。采用组内相关系数(intraclass correlation cofficient,ICC)评估两名观察者测量参数值的一致性。采用独立样本t检验或Mann-Whitney U检验分析两组病例各参数的差异。采用Logistic回归计算有统计学差异的参数联合评估直肠癌LVI的预测值。采用ROC曲线评估有差异参数单独或联合的诊断效能,并利用De-Long检验比较各ROC曲线间的差异。采用Pearson相关性检验分析两参数值的相关性。结果2名观察者测量T2值及ADC值一致性好(ICC>0.75)。脉管侵犯组的T2值及ADC值低于非脉管侵犯组(77.15±6.95ms、0.69±0.15mm^(2)/s vs 87.04±7.75ms、0.90±0.21 mm^(2)/s,P<0.05)。ADC值与ADC-T2联合鉴别两组疾病的AUC值比较差异具有统计学意义(P=0.036)。结论T2 mapping和DWI序列可预测直肠癌脉管侵犯,两序列联合效能提升,因此T2值与ADC值联合可为临床诊疗直肠癌脉管侵犯提供参考信息。 展开更多
关键词 直肠癌 脉管侵犯 磁共振成像 T2 mapping成像 弥散加权成像
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Research on Integrated Circuit Talent Stability Construction Based on Turnover Attribution in High-Precision, Specialized, and Innovative Enterprises
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作者 Mingjie Cheng Ziying Chen +1 位作者 Xiayuan Huang Zhixin Jian 《Proceedings of Business and Economic Studies》 2025年第5期87-94,共8页
With the intensifying competition in the integrated circuit(IC)industry,the high turnover rate of integrated circuit engineers has become a prominent issue affecting the technological continuity of high-precision,spec... With the intensifying competition in the integrated circuit(IC)industry,the high turnover rate of integrated circuit engineers has become a prominent issue affecting the technological continuity of high-precision,specialized,and innovative enterprises.As a representative of such enterprises,JL Technology has faced challenges to its R&D efficiency due to talent loss in recent years.This study takes this enterprise as a case to explore feasible paths to reduce turnover rates through optimizing training and career development systems.The research designs a method combining learning maps and talent maps,utilizes a competency model to clarify the direction for engineers’skill improvement,implements talent classification management using a nine-grid model,and achieves personalized training through Individual Development Plans(IDPs).Analysis of the enterprise’s historical data reveals that the main reasons for turnover are unclear career development paths and insufficient resources for skill improvement.After pilot implementation,the turnover rate in core departments decreased by 12%,and employee satisfaction with training increased by 24%.The results indicate that matching systematic talent reviews with dynamic learning resources can effectively enhance engineers’sense of belonging.This study provides a set of highly operational management tools for small and medium-sized high-precision,specialized,and innovative technology enterprises,verifies their applicability in such enterprises,and offers replicable experiences for similar enterprises to optimize their talent strategies[1]. 展开更多
关键词 high-precision specialized and innovative enterprises IC engineers Learning map Talent review Talent map
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MRI T2 Mapping定量参数与乳腺癌临床分期的关系研究
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作者 马书敏 岳志领 +4 位作者 李莹 许彩红 王静静 王娜 李建丽 《中国CT和MRI杂志》 2026年第3期76-79,共4页
目的分析磁共振成像(MRI)T2 mapping定量参数与乳腺癌临床分期的关系。方法回顾性分析2023年8月~2024年8月邯郸市中心医院收治的86例乳腺癌患者的临床资料,根据病理结果分为中早期组(54例)和晚期组(32例)。比较两组患者基线资料、MRI图... 目的分析磁共振成像(MRI)T2 mapping定量参数与乳腺癌临床分期的关系。方法回顾性分析2023年8月~2024年8月邯郸市中心医院收治的86例乳腺癌患者的临床资料,根据病理结果分为中早期组(54例)和晚期组(32例)。比较两组患者基线资料、MRI图像特征(形态、边缘、强化方式及纤维腺体类型)及T2 mapping定量参数(10th位数、90th位数、熵值及平均值)。绘制受试者工作特征曲线,以曲线下面积(AUC)评估T2 mapping定量参数对晚期乳腺癌的诊断效能。使用Pearson法分析T2 mapping定量参数与晚期乳腺癌的关系。结果两组患者基线资料、形态、边缘、强化方式、纤维腺体类型、90th位数及熵值比较,差异无统计学意义(P>0.05)。晚期组10th位数、平均值小于中早期组(P<0.05)。ROC曲线显示,T2 mapping定量参数中的10th位数、平均值诊断晚期乳腺癌的AUC分别为0.826、0.870,二者联合(并联)诊断晚期乳腺癌的AUC为0.899(95%CI:0.815~0.954),敏感度为87.50%,特异度为83.33%,联合诊断AUC高于单独指标(Z=6.997、9.274,均P<0.05)。Pearson法分析结果显示,T2 mapping定量参数中的10th位数、平均值与晚期乳腺癌呈明显负相关(P<0.05)。结论MRI T2 mapping定量参数中的10th位数、平均值与晚期乳腺癌呈明显相关性,可用于评估乳腺癌临床分期,联合检测有助于提高诊断准确性。 展开更多
关键词 磁共振成像 T2mapping定量参数 乳腺癌 临床分期 相关性
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Recent progress on high-precision construction of nanoarchitectured SERS substrates for ultrasensitive bio-medical sensors
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作者 Heguang Liu Ben Mou +8 位作者 Jinxin Li Na Tian Yiming Feng Xiaodong Cui Yury Kapitonov Huageng Liang Caiyin You Yuan Li Tianyou Zhai 《Advanced Powder Materials》 2025年第4期30-57,共28页
Surface-enhanced Raman spectroscopy(SERS)has evolved from a laboratory technique to a practical tool for ultra-sensitive detection,particularly in the biomedical field,where precise molecular identification is crucial... Surface-enhanced Raman spectroscopy(SERS)has evolved from a laboratory technique to a practical tool for ultra-sensitive detection,particularly in the biomedical field,where precise molecular identification is crucial.Despite significant advancements,a gap remains in the literature,as no comprehensive review systematically addresses the high-precision construction of SERS substrates for ultrasensitive biomedical detection.This review fills that gap by exploring recent progress in fabricating high-precision SERS substrates,emphasizing their role in enabling ultrasensitive bio-medical sensors.We carefully examine the key to these advancements is the precision engineering of substrates,including noble metals,semiconductors,carbon-based materials,and two-dimensional materials,which is essential for achieving the high sensitivity required for ultrasensitive detection.Applications in biomedical diagnostics and molecular analysis are highlighted.Finally,we address the challenges in SERS substrate preparation and outline future directions,focusing on improvement strategies,design concepts,and expanding applications for these advanced materials. 展开更多
关键词 SERS SERS substrates high-precision construction Ultrasensitive bio-medical sensors Enhancement mechanism
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High-precision large-aperture single-frame interferometric surface profile measurement method based on deep learning
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作者 Liang Tang Mingzhi Han +3 位作者 Shuai Yang Ye Sun Lirong Qiu Weiqian Zhao 《International Journal of Extreme Manufacturing》 2025年第5期481-492,共12页
Large-aperture optical components are of paramount importance in domains such as integrated circuits,photolithography,aerospace,and inertial confinement fusion.However,measuring their surface profiles relies predomina... Large-aperture optical components are of paramount importance in domains such as integrated circuits,photolithography,aerospace,and inertial confinement fusion.However,measuring their surface profiles relies predominantly on the phase-shifting approach,which involves collecting multiple interferograms and imposes stringent demands on environmental stability.These issues significantly hinder its ability to achieve real-time and dynamic high-precision measurements.Therefore,this study proposes a high-precision large-aperture single-frame interferometric surface profile measurement(LA-SFISPM)method based on deep learning and explores its capability to realize dynamic measurements with high accuracy.The interferogram is matched to the phase by training the data measured using the small aperture.The consistency of the surface features of the small and large apertures is enhanced via contrast learning and feature-distribution alignment.Hence,high-precision phase reconstruction of large-aperture optical components can be achieved without using a phase shifter.The experimental results show that for the tested mirror withΦ=820 mm,the surface profile obtained from LA-SFISPM is subtracted point-by-point from the ground truth,resulting in a maximum single-point error of 4.56 nm.Meanwhile,the peak-to-valley(PV)value is 0.0758λ,and the simple repeatability of root mean square(SR-RMS)value is 0.00025λ,which aligns well with the measured results obtained by ZYGO.In particular,a significant reduction in the measurement time(reduced by a factor of 48)is achieved compared with that of the traditional phase-shifting method.Our proposed method provides an efficient,rapid,and accurate method for obtaining the surface profiles of optical components with different diameters without employing a phase-shifting approach,which is highly desired in large-aperture interferometric measurement systems. 展开更多
关键词 large-aperture optical components single-frame interferometric surface profile deep learning dynamic high-precision measurement
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An efficient and high-precision algorithm for solving multiple deformation modes of elastic beams
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作者 Yunzhou WANG Binbin ZHENG +2 位作者 Lingling HU Nan SUN Minghui FU 《Applied Mathematics and Mechanics(English Edition)》 2025年第9期1753-1770,共18页
The elliptic integral method(EIM) is an efficient analytical approach for analyzing large deformations of elastic beams. However, it faces the following challenges.First, the existing EIM can only handle cases with kn... The elliptic integral method(EIM) is an efficient analytical approach for analyzing large deformations of elastic beams. However, it faces the following challenges.First, the existing EIM can only handle cases with known deformation modes. Second,the existing EIM is only applicable to Euler beams, and there is no EIM available for higher-precision Timoshenko and Reissner beams in cases where both force and moment are applied at the end. This paper proposes a general EIM for Reissner beams under arbitrary boundary conditions. On this basis, an analytical equation for determining the sign of the elliptic integral is provided. Based on the equation, we discover a class of elliptic integral piecewise points that are distinct from inflection points. More importantly, we propose an algorithm that automatically calculates the number of inflection points and other piecewise points during the nonlinear solution process, which is crucial for beams with unknown or changing deformation modes. 展开更多
关键词 elastic beam elliptic integral deformation mode transition equilibrium path high-precision algorithm
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MapColor-Agent:融合大语言模型与多智能体的行政区划图配色框架
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作者 魏智威 杨乃 +3 位作者 王一杰 廖华 周梦杰 许文嘉 《测绘学报》 北大核心 2026年第2期359-370,共12页
近年来,大语言模型在语义理解与任务推理方面取得显著进展,为地图设计智能化提供了一种技术途径。本文以行政区划图的配色设计为研究对象,提出并构建了一个融合大语言模型与多智能体的交互式智能地图配色框架——MapColor-Agent。该系... 近年来,大语言模型在语义理解与任务推理方面取得显著进展,为地图设计智能化提供了一种技术途径。本文以行政区划图的配色设计为研究对象,提出并构建了一个融合大语言模型与多智能体的交互式智能地图配色框架——MapColor-Agent。该系统以大语言模型为语义理解核心,通过多智能体实现任务分解与过程协同,并结合自然语言和图形化操作界面,支持用户以更直观的方式生成符合需求的地图配色方案。本文采用系统可用性量表与半结构化访谈评估系统性能。结果表明,MapColor-Agent的总体可用性得分为77.9,达到良好水平。用户普遍认为系统学习成本低、操作流程清晰、交互体验自然,且具有较高的可理解性和控制性。差异性分析显示,熟悉地图配色的用户在学习效率与系统复杂度感知方面得分更高,说明知识背景对系统使用效果具有一定影响。访谈结果进一步表明,系统在语义理解与任务引导方面表现出优势,但在复杂语义解析与生成稳定性方面仍有改进空间。研究结果验证了大语言模型与智能体协同架构在地图配色设计中的可行性,可为未来基于语义推理与多模态交互的地图智能设计提供参考。 展开更多
关键词 大语言模型 多智能体系统 人机交互 地图配色设计 行政区划图
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Hot Compression Deformation Behavior and Processing Maps of Mg-Zn-Mn(-Sn)-Ca Alloy
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作者 Chen Xia Zhu Yulong +2 位作者 Liu Quanyi Zhang Dingfei Pan Fusheng 《稀有金属材料与工程》 北大核心 2026年第3期627-635,共9页
The hot compression deformation behavior of Mg-6Zn-1Mn-0.5Ca(ZM61-0.5Ca)and Mg-6Zn-1Mn-2Sn-0.5Ca(ZMT612-0.5Ca)alloys was investigated at deformation temperatures ranging from 250℃to 400℃and strain rates varying from... The hot compression deformation behavior of Mg-6Zn-1Mn-0.5Ca(ZM61-0.5Ca)and Mg-6Zn-1Mn-2Sn-0.5Ca(ZMT612-0.5Ca)alloys was investigated at deformation temperatures ranging from 250℃to 400℃and strain rates varying from 0.001 s^(-1) to 1 s^(-1).The results show that the addition of Sn promotes dynamic recrystallization(DRX),and CaMgSn phases can act as nucleation sites during the compression deformation.Flow stress increases with increasing the strain rate and decreasing the temperature.Both the ZM61-0.5Ca and ZMT612-0.5Ca alloys exhibit obvious DRX characteristics.CaMgSn phases can effectively inhibit dislocation motion with the addition of Sn,thus increasing the peak fl ow stress of the alloy.The addition of Sn increases the hot deformation activation energy of the ZM61-0.5Ca alloy from 199.654 kJ/mol to 276.649 kJ/mol,thus improving the thermal stability of the alloy.For the ZMT612-0.5Ca alloy,the optimal hot deformation parameters are determined to be a deformation temperature range of 350–400℃and a strain rate range of 0.001–0.01 s^(-1). 展开更多
关键词 hot deformation constitutive equation processing map deformation activation energy magnesium alloy
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基于网络药理学及动物实验探讨补阳还五汤通过miR-30e-5p调控MAP3K5治疗低氧性肺动脉高压作用机制
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作者 王凯心 秦一冰 曲妮妮 《辽宁中医药大学学报》 2026年第3期15-24,共10页
目的基于网络药理学与动物实验探讨补阳还五汤对低氧性肺动脉高压(hypoxic pulmonary hypertension,HPH)大鼠血管重构的影响及其作用机制。方法(1)网络药理学实验。使用TCMSP、HERB、GeneCards、OMIM以及UniProt等公共数据库,筛选补阳... 目的基于网络药理学与动物实验探讨补阳还五汤对低氧性肺动脉高压(hypoxic pulmonary hypertension,HPH)大鼠血管重构的影响及其作用机制。方法(1)网络药理学实验。使用TCMSP、HERB、GeneCards、OMIM以及UniProt等公共数据库,筛选补阳还五汤和肺动脉高压(pulmonary arterial hypertension,PAH)的靶点基因并标准化;进行蛋白互作(protein-protein interaction,PPI)网络以及基因本体论(gene ontology,GO)和京都基因与基因组百科全书(Kyoto encyclopedia of genes and genomes,KEGG)通路富集分析;制作靶点交集韦恩图和“药物-成分-靶点-疾病”网络图;建立miRNAs-mRNAs网络互作图。(2)动物实验。将SD雄性大鼠50只随机分成5组,分别为空白组、模型组、中药低剂量组、中药中剂量组及中药高剂量组,每组10只,使用低氧暴露法建立HPH大鼠模型。4周后检测各组大鼠右心室压力;免疫组化测定肺小动脉细胞核抗原(proliferating cell nuclear antigen,PCNA)的表达;ELISA法检测血清中P27^(kip1)的表达;Western blot法检测肺组织增殖、凋亡及通路相关蛋白的表达水平;实时定量逆转录聚合酶链反应(reverse transcription quantitative PCR,RT-qPCR)法检测各组大鼠肺组织中miR-30e-5p和丝裂原活化蛋白激酶激酶激酶5信号通路(mitogen-activated protein kinase kinase kinase 5 signaling pathway,MAP3K5)mRNA的表达。结果(1)网络药理学结果显示,补阳还五汤活性成分109个,相关靶点495个,疾病相关靶点7789个,交集靶点235个;GO功能富集分析共获得1038个条目,分别为生物过程(biological process,BP)774条、细胞组分(cellular component,CC)91条及分子功能(molecular function,MF)173条,KEGG富集结果175条;网络图分析出前5个主要疾病通路为肿瘤坏死因子(tumor necrosis factor,TNF)信号通路、白细胞介素-17(interleukin-17,IL-17)信号通路、晚期糖基化终末产物-其受体(advanced glycation end productsreceptor for AGE,AGE-RAGE)信号通路、MAP3K5和lipid and atherosclerosis信号通路;miRNAs-mRNAs网络互作图得出miR-30e-5p和MAP3K5关系密切。(2)与空白组相比,模型组右心室压力显著上升,肺小动脉结构改变;MAP3K5 mRNA及MAP3K5、B-细胞淋巴瘤2(B-cell lymphoma 2,Bcl-2)蛋白表达增加(P<0.01);miR-30e-5p mRNA及P27^(kip1)、细胞色素C(cytochrome C,Cyt C)、Bcl-2关联X蛋白(Bcl-2-associated X protein,Bax)、半胱天冬酶-3(Caspase-3)及半胱天冬酶-9(Caspase-9)蛋白表达降低(P<0.01);与模型组相比,中药各剂量组则显著降低了右心室压力,改善了肺小动脉结构,MAP3K5 mRNA及MAP3K5、Bcl-2蛋白表达减低(P<0.01),miR-30e-5p mRNA、P27^(kip1)、Cyt C、Bax、Caspase-3及Caspase-9蛋白表达升高(P<0.01或P<0.05)。结论该网络药理学和实验基本阐明,补阳还五汤可以通过miR-30e-5p调控MAP3K5,从而抑制增殖和促进凋亡,改善HPH大鼠肺血管重构,降低肺动脉压力。 展开更多
关键词 低氧性肺动脉高压 补阳还五汤 miR-30e-5p map3K5
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A Comprehensive Literature Review of AI-Driven Application Mapping and Scheduling Techniques for Network-on-Chip Systems
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作者 Naveed Ahmad Muhammad Kaleem +5 位作者 Mourad Elloumi Muhammad Azhar Mushtaq Ahlem Fatnassi Mohd Fazil Anas Bilal Abdulbasit A.Darem 《Computer Modeling in Engineering & Sciences》 2026年第1期118-155,共38页
Network-on-Chip(NoC)systems are progressively deployed in connecting massively parallel megacore systems in the new computing architecture.As a result,application mapping has become an important aspect of performance ... Network-on-Chip(NoC)systems are progressively deployed in connecting massively parallel megacore systems in the new computing architecture.As a result,application mapping has become an important aspect of performance and scalability,as current trends require the distribution of computation across network nodes/points.In this paper,we survey a large number of mapping and scheduling techniques designed for NoC architectures.This time,we concentrated on 3D systems.We take a systematic literature review approach to analyze existing methods across static,dynamic,hybrid,and machine-learning-based approaches,alongside preliminary AI-based dynamic models in recent works.We classify them into several main aspects covering power-aware mapping,fault tolerance,load-balancing,and adaptive for dynamic workloads.Also,we assess the efficacy of each method against performance parameters,such as latency,throughput,response time,and error rate.Key challenges,including energy efficiency,real-time adaptability,and reinforcement learning integration,are highlighted as well.To the best of our knowledge,this is one of the recent reviews that identifies both traditional and AI-based algorithms for mapping over a modern NoC,and opens research challenges.Finally,we provide directions for future work toward improved adaptability and scalability via lightweight learned models and hierarchical mapping frameworks. 展开更多
关键词 Application mapping mapping techniques NETWORK-ON-CHIP system on chip optimisation
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3D Spectrum Mapping and Reconstruction Under Multi-Radiation Source Scenarios
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作者 Wang Jie Lin Zhipeng +5 位作者 Zhu Qiuming Wu Qihui Lan Tianxu Zhao Yi Bai Yunpeng Zhong Weizhi 《China Communications》 2026年第2期20-34,共15页
Spectrum map construction,which is crucial in cognitive radio(CR)system,visualizes the invisible space of the electromagnetic spectrum for spectrum-resource management and allocation.Traditional reconstruction methods... Spectrum map construction,which is crucial in cognitive radio(CR)system,visualizes the invisible space of the electromagnetic spectrum for spectrum-resource management and allocation.Traditional reconstruction methods are generally for twodimensional(2D)spectrum map and driven by abundant sampling data.In this paper,we propose a data-model-knowledge-driven reconstruction scheme to construct the three-dimensional(3D)spectrum map under multi-radiation source scenarios.We firstly design a maximum and minimum path loss difference(MMPLD)clustering algorithm to detect the number of radiation sources in a 3D space.Then,we develop a joint location-power estimation method based on the heuristic population evolutionary optimization algorithm.Considering the variation of electromagnetic environment,we self-learn the path loss(PL)model based on the sampling data.Finally,the 3D spectrum is reconstructed according to the self-learned PL model and the extracted knowledge of radiation sources.Simulations show that the proposed 3D spectrum map reconstruction scheme not only has splendid adaptability to the environment,but also achieves high spectrum construction accuracy even when the sampling rate is very low. 展开更多
关键词 cognitive radio map reconstruction path loss model radiation source 3D spectrum map
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基于双参数MRI弥散加权成像和T_(2)mapping成像对前列腺癌的诊断价值
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作者 王永胜 陈文静 +1 位作者 何俊林 马财 《影像研究与医学应用》 2026年第5期28-31,36,共5页
目的:探讨基于双参数MRI(bpMRI)的表观弥散系数(ADC)值、T_(2)mapping值及临床指标对前列腺癌(PCa)的诊断价值。方法:回顾性分析2022年11月—2025年1月上海市金山区亭林医院收治的93例疑似PCa的患者bpMRI图像,完成前列腺影像报告和数据... 目的:探讨基于双参数MRI(bpMRI)的表观弥散系数(ADC)值、T_(2)mapping值及临床指标对前列腺癌(PCa)的诊断价值。方法:回顾性分析2022年11月—2025年1月上海市金山区亭林医院收治的93例疑似PCa的患者bpMRI图像,完成前列腺影像报告和数据系统(PI-RADS)评分,并测量病灶的ADC值、T_(2)mapping值,记录患者年龄、总前列腺特异性抗原(t-PSA)、游离前列腺特异性抗原(f-PSA)、f-PSA/t-PSA(f/t)值及PSA密度值等临床指标。采用Logistic回归分析临床指标、ADC值及T_(2)mapping值与PCa的关系,构建基于双参数、ADC值及T_(2)mapping值的联合诊断模型,通过受试者工作特征(ROC)曲线评估ADC值、T_(2)mapping值、双参数PI-RADS评分及其分别联合ADC值或T_(2)mapping值的诊断效能。结果:非PCa与PCa患者的PSA密度、ADC值、T_(2)mapping值比较,差异有统计学意义(P<0.05)。ADC值与T_(2)mapping值诊断PCa的效能均较高(P<0.05),双参数PI-RADS评分、联合ADC值、联合T_(2)mapping值诊断外周带PCa的曲线下面积(AUC)分别为0.883、0.918和0.902;诊断移行带PCa的AUC分别为0.798、0.810和0.817。结论:对于临床指标提示恶性可能的前列腺疾病患者,bpMRI联合ADC值与T_(2)mapping值可显著提高PCa的诊断效能。 展开更多
关键词 双参数磁共振成像 表观弥散系数 T_(2)mapping 临床指标 前列腺癌
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