An integration of single-layer proximitycoupling patch antenna and solar cells with bandwidth enhancement and optical energy harvesting is proposed for sustainable communication.For this purpose,many dual-function com...An integration of single-layer proximitycoupling patch antenna and solar cells with bandwidth enhancement and optical energy harvesting is proposed for sustainable communication.For this purpose,many dual-function components are selected for designing the miniaturized solar cell antenna.On the one hand,by greatly affecting the current flow of the rectangular patch,vias and proximity-coupling are introduced to control the resonance modes frequency and matching,respectively,for wideband application,and the radiation performance property can be achieved by high-order mode.On the other hand,vias and proximity-coupling are beneficial to complete direct-current(DC)loop of solar cell and improve compatibility of DC-RF(radio frequency),whereas a high-order mode is beneficial to increase the area of collected light energy.To prove the working principle,fabricated and manufactured solar cell antenna.The measured and simulated results illustrate that the solar cell antenna gain is raised to as high as 9.27 d Bi in4.37 to 5.06 GHz applied to fifth generation communication(5G).展开更多
This paper presents a detailed investigation, via field experiment, into the mechanism of high-order polygonal wear of wheels of a new type of high-speed train. The investigation was carried out during the performance...This paper presents a detailed investigation, via field experiment, into the mechanism of high-order polygonal wear of wheels of a new type of high-speed train. The investigation was carried out during the performance acceptance test of the train and its initial commercial operation. The investigation covered the performance acceptance test of 150 000 km and the commercial operation of about 150 000 km. In the performance acceptance test of the first stage of about 70 000 km, at 200-250 km/h with full loading and sometimes overloading by 30%, the serious polygonal wear of 23-order took place on all the wheels of the train, and was measured and analyzed in detail. All the potygonized wheels were re-profiled because the polygonal wear had caused strong vibration and damage to the train parts. After re-profiling, the vibration of the train and track and the wear status of the wheels were measured and analyzed at different test mileages according to the polygonal wear situation of the wheels. The measured vibration of the train includes the accelerations at different positions of a motor car and a trail car. The vibration modes of the key parts of the bogies of the two cars were calculated. Meanwhile, the track resonant frequencies were investigated at the site. The purpose of the above tests and analysis is try to find the frequency of work mode matching the passing frequency of the high-order wheel polygon. The present investigation shows that one of the working models causes the formation and development of the high-order wheel polygonal wear. The growth of this wear was effectively reduced through the frequent changing of the running speed of the train operating on the way back and forth every day.展开更多
AIM To evaluate the utility of patch test and cross-sensitivity patterns in patients with adverse cutaneous drug reactions(ACDR) from common anticonvulsants. METHODS Twenty-four(M:F = 13:11) patients aged 18-75 years ...AIM To evaluate the utility of patch test and cross-sensitivity patterns in patients with adverse cutaneous drug reactions(ACDR) from common anticonvulsants. METHODS Twenty-four(M:F = 13:11) patients aged 18-75 years with ACDR from anticonvulsants were patch tested 3-27 mo after complete recovery using carbamazepine, phenytoin, phenobarbitone, lamotrigine, and sodium valproate in 10%, 20% and 30% conc. in pet. after informed consent. Positive reactions persisting on D3 and D4 were considered significant. RESULTS Clinical patterns were exanthematous drug rash with or without systemic involvement(DRESS) in 18(75%), Stevens-Johnsons syndrome/toxic epidermal necrolysis(SJS/TEN) overlap and TEN in 2(8.3%) patients each, SJS and lichenoid drug eruption in 1(4.2%) patient each, respectively. The implicated drugs were phenytoin in 14(58.3%), carbamazepine in 9(37.5%), phenobarbitone in 2(8.3%), and lamotrigine in 1(4.7%) patients,respectively. Twelve(50%) patients elicited positive reactions to implicated drugs; carbamazepine in 6(50%), phenytoin alone in 4(33.3%), phenobarbitone alone in 1(8.3%), and both phenytoin and phenobarbitone in 1(8.33%) patients, respectively. Cross-reactions occurred in 11(92%) patients. Six patients with carbamazepine positive patch test reaction showed cross sensitivity with phenobarbitone, sodium valproate and/or lamotrigine. Three(75%) patients among positive phenytoin patch test reactions had cross reactions with phenobarbitone, lamotrigine, and/or valproate. CONCLUSION Carbamazepine remains the commonest anticonvulsant causing ACDRs and cross-reactions with other anticonvulsants are possible. Drug patch testing appears useful in DRESS for drug imputability and cross-reactions established clinically.展开更多
The paper investigates the foaming and mildness properties of trehalolipids surfactant in rinse-off formulations,comparing it with the traditional nonionic surfactant alkyl-polyglycolide(APG).Both single surfactant an...The paper investigates the foaming and mildness properties of trehalolipids surfactant in rinse-off formulations,comparing it with the traditional nonionic surfactant alkyl-polyglycolide(APG).Both single surfactant and their surfactant complexes are evaluated.And the results show that trehalolipids have significant advantages in reducing surface tension,improving foam performance,and enhancing mildness.For mildness evaluation,multiple methods are employed in the study,including in vitro cell toxicity,inflammatory markers,colorimetric index of mildness CIM,and in vivo method of human skin patch test.The results show that the addition of trehalolipids increases IC50 and reduces the release of inflammatory markers of the binary surfactant system.However,the incorporation of trehalolipids has some negative effects on the skin’s lipid barrier function.Skin patch test results indicate that the addition of trehalolipids improves the mildness of surfactant system,particularly in sulfate-free system.Overall,trehalolipids,as nonionic surfactants,presents great potential to replace traditional surfactants in rinse off formulations with enhanced mildness and foam performance.展开更多
Spacecraft automatic test system, a comprehensive spacecraft test information system based on the various spacecraft test specifications formalized as spacecraft test language, is an important means to improve test ef...Spacecraft automatic test system, a comprehensive spacecraft test information system based on the various spacecraft test specifications formalized as spacecraft test language, is an important means to improve test efficiency. With the new require- ments of the multi-spacecraft test in China, the study of the spacecraft test language becomes a new challenge for spacecraft test field. In this article, a high-order spacecraft test language, China aerospace test and operation language （CATOL）, is given asso- ciated with the current test requirements; meanwhile, the structure of the language is presented. Then, for characterizing and formalizing the spacecraft processes, the syntax and operational semantics of one of the sub-languages, CATOL-PR, are defined. Finally, the prototype system of this proposed language is presented. This language will improve the specification of spacecraft test work in China and the efficiency of spacecraft testers, and promote the development in spacecraft automatic test.展开更多
The interfacial debonding in fiber-reinforced plastic(FRP)strengthened repair material will affect the bonding strength and lead to failure of the repair without warning.Unfortunately the interfacial damage is normall...The interfacial debonding in fiber-reinforced plastic(FRP)strengthened repair material will affect the bonding strength and lead to failure of the repair without warning.Unfortunately the interfacial damage is normally invisible and often in the form of a patch rather than a through-width crack.Therefore,a debonding patch detection technique based on fiber optic interferometry is proposed.A quasi-impulse loading is applied with a rubberhead hammer and the total elongation of a surface-mounted optical fiber along the length of the repair material is measured as a function of load position.When a debonding patch is present,the induced sudden slope or sign change on the plot of fiber integral strain v.s.load position will reveal the extent and the location of the debonded area.The results of the study indicate that the proposed technique is applicable for debonding patch detection in repaired members under various support conditions.展开更多
结核病(tuberculosis,TB)流行病快速筛查常采用结核菌素纯蛋白衍生物(pure protein derivative,PPD)皮试,但特异性低,不良反应大。ESAT-6和CFP-10是结核分枝杆菌的分泌蛋白,但卡介苗(Bacillus Calmette-Guerin,BCG)中缺失了相关基因。...结核病(tuberculosis,TB)流行病快速筛查常采用结核菌素纯蛋白衍生物(pure protein derivative,PPD)皮试,但特异性低,不良反应大。ESAT-6和CFP-10是结核分枝杆菌的分泌蛋白,但卡介苗(Bacillus Calmette-Guerin,BCG)中缺失了相关基因。本研究表达纯化了结核分枝杆菌的分泌蛋白ESAT6和CFP10的融合蛋白(ESAT6 and CFP10 fusion protein,EC),并制备成其壳聚糖纳米粒(ESAT6 and CFP10 fusion protein nanoparticals,EC-NPs),进一步制备成透明质酸可溶性微针贴片(microneedle patch,MNP)。MNP-EC-NPs载药量达到每针0.03μg,每片可达到1.92μg,常温下保存期可达6个月,可有效透过表皮。志愿者皮试结果显示MNP-EC-NPs可有效区分BCG接种者,在结核病患者皮肤有效显示阳性反应,无显著不良反应,实验经武汉市肺科医院伦理委员会批准[武肺伦理2022(2)]。本研究建立了一种结核病皮试方法,采用ESAT6-CFP10融合蛋白替代PPD,并采用可溶性微针剂型,提高了结核病皮试诊断的特异性,为结核流行病筛查提供了新的技术方案。展开更多
基金supported by the National Natural Science Foundation of China(62101380)Tianjin Key Laboratory of Imaging and Sensing Microelectronic Technology。
文摘An integration of single-layer proximitycoupling patch antenna and solar cells with bandwidth enhancement and optical energy harvesting is proposed for sustainable communication.For this purpose,many dual-function components are selected for designing the miniaturized solar cell antenna.On the one hand,by greatly affecting the current flow of the rectangular patch,vias and proximity-coupling are introduced to control the resonance modes frequency and matching,respectively,for wideband application,and the radiation performance property can be achieved by high-order mode.On the other hand,vias and proximity-coupling are beneficial to complete direct-current(DC)loop of solar cell and improve compatibility of DC-RF(radio frequency),whereas a high-order mode is beneficial to increase the area of collected light energy.To prove the working principle,fabricated and manufactured solar cell antenna.The measured and simulated results illustrate that the solar cell antenna gain is raised to as high as 9.27 d Bi in4.37 to 5.06 GHz applied to fifth generation communication(5G).
基金Project supported by the National Natural Science Foundation of China （No. U 1134202）
文摘This paper presents a detailed investigation, via field experiment, into the mechanism of high-order polygonal wear of wheels of a new type of high-speed train. The investigation was carried out during the performance acceptance test of the train and its initial commercial operation. The investigation covered the performance acceptance test of 150 000 km and the commercial operation of about 150 000 km. In the performance acceptance test of the first stage of about 70 000 km, at 200-250 km/h with full loading and sometimes overloading by 30%, the serious polygonal wear of 23-order took place on all the wheels of the train, and was measured and analyzed in detail. All the potygonized wheels were re-profiled because the polygonal wear had caused strong vibration and damage to the train parts. After re-profiling, the vibration of the train and track and the wear status of the wheels were measured and analyzed at different test mileages according to the polygonal wear situation of the wheels. The measured vibration of the train includes the accelerations at different positions of a motor car and a trail car. The vibration modes of the key parts of the bogies of the two cars were calculated. Meanwhile, the track resonant frequencies were investigated at the site. The purpose of the above tests and analysis is try to find the frequency of work mode matching the passing frequency of the high-order wheel polygon. The present investigation shows that one of the working models causes the formation and development of the high-order wheel polygonal wear. The growth of this wear was effectively reduced through the frequent changing of the running speed of the train operating on the way back and forth every day.
文摘AIM To evaluate the utility of patch test and cross-sensitivity patterns in patients with adverse cutaneous drug reactions(ACDR) from common anticonvulsants. METHODS Twenty-four(M:F = 13:11) patients aged 18-75 years with ACDR from anticonvulsants were patch tested 3-27 mo after complete recovery using carbamazepine, phenytoin, phenobarbitone, lamotrigine, and sodium valproate in 10%, 20% and 30% conc. in pet. after informed consent. Positive reactions persisting on D3 and D4 were considered significant. RESULTS Clinical patterns were exanthematous drug rash with or without systemic involvement(DRESS) in 18(75%), Stevens-Johnsons syndrome/toxic epidermal necrolysis(SJS/TEN) overlap and TEN in 2(8.3%) patients each, SJS and lichenoid drug eruption in 1(4.2%) patient each, respectively. The implicated drugs were phenytoin in 14(58.3%), carbamazepine in 9(37.5%), phenobarbitone in 2(8.3%), and lamotrigine in 1(4.7%) patients,respectively. Twelve(50%) patients elicited positive reactions to implicated drugs; carbamazepine in 6(50%), phenytoin alone in 4(33.3%), phenobarbitone alone in 1(8.3%), and both phenytoin and phenobarbitone in 1(8.33%) patients, respectively. Cross-reactions occurred in 11(92%) patients. Six patients with carbamazepine positive patch test reaction showed cross sensitivity with phenobarbitone, sodium valproate and/or lamotrigine. Three(75%) patients among positive phenytoin patch test reactions had cross reactions with phenobarbitone, lamotrigine, and/or valproate. CONCLUSION Carbamazepine remains the commonest anticonvulsant causing ACDRs and cross-reactions with other anticonvulsants are possible. Drug patch testing appears useful in DRESS for drug imputability and cross-reactions established clinically.
文摘The paper investigates the foaming and mildness properties of trehalolipids surfactant in rinse-off formulations,comparing it with the traditional nonionic surfactant alkyl-polyglycolide(APG).Both single surfactant and their surfactant complexes are evaluated.And the results show that trehalolipids have significant advantages in reducing surface tension,improving foam performance,and enhancing mildness.For mildness evaluation,multiple methods are employed in the study,including in vitro cell toxicity,inflammatory markers,colorimetric index of mildness CIM,and in vivo method of human skin patch test.The results show that the addition of trehalolipids increases IC50 and reduces the release of inflammatory markers of the binary surfactant system.However,the incorporation of trehalolipids has some negative effects on the skin’s lipid barrier function.Skin patch test results indicate that the addition of trehalolipids improves the mildness of surfactant system,particularly in sulfate-free system.Overall,trehalolipids,as nonionic surfactants,presents great potential to replace traditional surfactants in rinse off formulations with enhanced mildness and foam performance.
基金National Natural Science Foundation of China （61003016） Supported Project of the State Key Laboratory of Software Development Environment （SKLSDE-2009ZX-13）
文摘Spacecraft automatic test system, a comprehensive spacecraft test information system based on the various spacecraft test specifications formalized as spacecraft test language, is an important means to improve test efficiency. With the new require- ments of the multi-spacecraft test in China, the study of the spacecraft test language becomes a new challenge for spacecraft test field. In this article, a high-order spacecraft test language, China aerospace test and operation language （CATOL）, is given asso- ciated with the current test requirements; meanwhile, the structure of the language is presented. Then, for characterizing and formalizing the spacecraft processes, the syntax and operational semantics of one of the sub-languages, CATOL-PR, are defined. Finally, the prototype system of this proposed language is presented. This language will improve the specification of spacecraft test work in China and the efficiency of spacecraft testers, and promote the development in spacecraft automatic test.
基金supported by the National Natural Science Foundation of China(No.51278156)the Basic Project of Shenzhen Science & Technology Program(No.JCYJ2017030155815876)
文摘The interfacial debonding in fiber-reinforced plastic(FRP)strengthened repair material will affect the bonding strength and lead to failure of the repair without warning.Unfortunately the interfacial damage is normally invisible and often in the form of a patch rather than a through-width crack.Therefore,a debonding patch detection technique based on fiber optic interferometry is proposed.A quasi-impulse loading is applied with a rubberhead hammer and the total elongation of a surface-mounted optical fiber along the length of the repair material is measured as a function of load position.When a debonding patch is present,the induced sudden slope or sign change on the plot of fiber integral strain v.s.load position will reveal the extent and the location of the debonded area.The results of the study indicate that the proposed technique is applicable for debonding patch detection in repaired members under various support conditions.
文摘结核病(tuberculosis,TB)流行病快速筛查常采用结核菌素纯蛋白衍生物(pure protein derivative,PPD)皮试,但特异性低,不良反应大。ESAT-6和CFP-10是结核分枝杆菌的分泌蛋白,但卡介苗(Bacillus Calmette-Guerin,BCG)中缺失了相关基因。本研究表达纯化了结核分枝杆菌的分泌蛋白ESAT6和CFP10的融合蛋白(ESAT6 and CFP10 fusion protein,EC),并制备成其壳聚糖纳米粒(ESAT6 and CFP10 fusion protein nanoparticals,EC-NPs),进一步制备成透明质酸可溶性微针贴片(microneedle patch,MNP)。MNP-EC-NPs载药量达到每针0.03μg,每片可达到1.92μg,常温下保存期可达6个月,可有效透过表皮。志愿者皮试结果显示MNP-EC-NPs可有效区分BCG接种者,在结核病患者皮肤有效显示阳性反应,无显著不良反应,实验经武汉市肺科医院伦理委员会批准[武肺伦理2022(2)]。本研究建立了一种结核病皮试方法,采用ESAT6-CFP10融合蛋白替代PPD,并采用可溶性微针剂型,提高了结核病皮试诊断的特异性,为结核流行病筛查提供了新的技术方案。
