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Wavelet Transform-Based High-Definition Map Construction From a Panoramic Camera 被引量:1
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作者 ZHUANG Hanyang ZHOU Xuejun +1 位作者 WANG Chunxiang QIAN Yuhan 《Journal of Shanghai Jiaotong university(Science)》 EI 2021年第5期569-576,共8页
High-definition(HD)maps are key components that provide rich topologic and semantic information for decision-making in vehicle autonomous driving systems.A complete ground orthophoto is usually used as the base image ... High-definition(HD)maps are key components that provide rich topologic and semantic information for decision-making in vehicle autonomous driving systems.A complete ground orthophoto is usually used as the base image to construct the HD map.The ground orthophoto is obtained through inverse perspective transformation and image mosaicing.During the image mosaicing,multiple consecutive orthophotos are stitched together using pose information and image registration.In this study,wavelet transform is introduced to the image mosaicing process to alleviate the information loss caused by image overlapping.In the orthophoto wavelet transform,high-frequency and low-frequency components are fused using different strategies to form a complete base image with clearer local details.Experimental results show that the accuracy of the orthophotos generated using this method is improved. 展开更多
关键词 high-definition(HD)map wavelet transform image registration PANORAMA
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Open HD map service model:an interoperable high-Definition map data model for autonomous driving 被引量:2
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作者 Fengyuan Zhang Wenzhong Shi +2 位作者 Min Chen Wei Huang Xintao Liu 《International Journal of Digital Earth》 SCIE EI 2023年第1期2089-2110,共22页
With the growth in the vehicle industry,autonomous driving has become a hot topic worldwide and has attracted increasing attention from both industrial and academic sectors.Maps,as pivotal geospatial information carri... With the growth in the vehicle industry,autonomous driving has become a hot topic worldwide and has attracted increasing attention from both industrial and academic sectors.Maps,as pivotal geospatial information carriers,play a vital role in route planning and navigation service.Compared with conventional maps,high-definition(HD)maps possesses higher precision,richer information,and various services and are regarded as critical infrastructure for autonomous driving.However,heterogeneous HD map data standards and models have different characteristics and advantages,and thus they rarely meet all autonomous driving requirements for different driving objectives.This research presents an interoperable map data model,the Open HD Map Service Model(OHDMSM),to provide a reference for HD map development.The designed OHDMSM,which contains three data layers and a set of corresponding interfaces,demonstrates high interoperability for HD map data fusion and application.As a proof of concept,an HD map data system is implemented with all functions following the designed data model and interfaces of OHDMSM.The design and development of OHDMSM data structures,interfaces and systems will benefit data requesting,updating,and interoperation for HD map data worldwide,which can be helpful for developing autonomous driving and intelligent transportation in the Digital Earth. 展开更多
关键词 HD map data interoperation autonomous driving data standards smart cities
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Secure task offloading strategy optimization of UAV-aided outdoor mobile high-definition live streaming
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作者 Ming YAN Yuxuan ZHANG +2 位作者 Chien Aun CHAN André F.GYGAX Chunguo LI 《Chinese Journal of Aeronautics》 2025年第10期201-215,共15页
Unmanned aerial vehicles(UAVs)bring more innovation and attraction to outdoor mobile high-definition(HD)live streaming with its unique perspective.Due to the heavy computational requirements of HD live broadcast tasks... Unmanned aerial vehicles(UAVs)bring more innovation and attraction to outdoor mobile high-definition(HD)live streaming with its unique perspective.Due to the heavy computational requirements of HD live broadcast tasks and the limited hardware performance of UAV equipment,how to reduce the system response delay and improve the energy efficiency of terminal equipment directly affects the secure broadcast of the system.Secure task offloading in this scenario is considered a promising solution and has received academic attention.In this paper,we simulate the UAV-aided outdoor mobile HD live streaming scenarios and optimize the relevant task offloading strategies.First,we design the total cost function of task offloading that jointly optimizes secure time latency and energy consumption.Additionally,we propose a collaborative computing model for multi-UAV task offloading.This model combines the idea of simulated annealing(SA)and introduces the compression factor to enhance the particle swarm optimization(PSO)to realize secure task offloading.The simulation results show that the proposed strategy has better performance in balancing network latency and energy consumption.Compared with the discrete teaching–learning-based optimization(DTLBO)and quantum PSO(QPSO)task offloading strategies,the fitness value of the proposed strategy is decreased by an average of 26.73%and 16.42%,respectively. 展开更多
关键词 Unmanned aerial vehicle(UAV) high-definition(HD)live streaming Secure task offloading Network energy consumption Particle swarm optimization(PSO)
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Processing map for oxide dispersion strengthening Cu alloys based on experimental results and machine learning modelling
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作者 Le Zong Lingxin Li +8 位作者 Lantian Zhang Xuecheng Jin Yong Zhang Wenfeng Yang Pengfei Liu Bin Gan Liujie Xu Yuanshen Qi Wenwen Sun 《International Journal of Minerals,Metallurgy and Materials》 2026年第1期292-305,共14页
Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening pa... Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening particles also deteriorates the processability and it is of great importance to establish accurate processing maps to guide the thermomechanical processes to enhance the formability.In this study,we performed particle swarm optimization-based back propagation artificial neural network model to predict the high temperature flow behavior of 0.25wt%Al2O3 particle-reinforced Cu alloys,and compared the accuracy with that of derived by Arrhenius-type constitutive model and back propagation artificial neural network model.To train these models,we obtained the raw data by fabricating ODS Cu alloys using the internal oxidation and reduction method,and conducting systematic hot compression tests between 400 and800℃with strain rates of 10^(-2)-10 S^(-1).At last,processing maps for ODS Cu alloys were proposed by combining processing parameters,mechanical behavior,microstructure characterization,and the modeling results achieved a coefficient of determination higher than>99%. 展开更多
关键词 oxide dispersion strengthened Cu alloys constitutive model machine learning hot deformation processing maps
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梨形环棱螺Map2k1基因的分子特征和功能分析
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作者 金鑫 缪煜琳 +3 位作者 王萍 顾洋 吕伙红 汪桂玲 《上海海洋大学学报》 北大核心 2025年第6期1203-1213,共11页
为了探究Map2k1基因在梨形环棱螺性腺发育及性别分化中的作用,采用基因克隆、实时荧光定量、原位杂交以及RNA干扰技术来研究Map2k1在梨形环棱螺中的表达和功能。结果显示,Map2k1 cDNA ORF区全长1191 bp,编码396个氨基酸,MAP2K1蛋白中含... 为了探究Map2k1基因在梨形环棱螺性腺发育及性别分化中的作用,采用基因克隆、实时荧光定量、原位杂交以及RNA干扰技术来研究Map2k1在梨形环棱螺中的表达和功能。结果显示,Map2k1 cDNA ORF区全长1191 bp,编码396个氨基酸,MAP2K1蛋白中含有S_TKc结构域,其氨基酸序列与软体动物同源性较高。Map2k1在雄性和雌性多种组织中均有表达,尤其是在雌性性腺中的表达量最高,且雌雄性腺的表达水平存在极显著差异(P<0.01)。原位杂交的结果表明,在雌性梨形环棱螺卵母细胞和卵巢囊泡中,Map2k1存在明显的杂交信号。RNA干扰的结果显示,在雌性梨形环棱螺中,Map2k1的干扰链G1在注射后12 h达到最高干扰率,为73.1%,并导致其他性别相关基因β-catenin、Cyp17a1和Sox9表达量显著降低。研究表明,Map2k1可能参与了雌性梨形环棱螺性腺发育和性别分化过程。本研究可为梨形环棱螺性腺发育和单性化育种研究提供理论参考。 展开更多
关键词 梨形环棱螺 map2k1基因 性腺发育 RNA干扰
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3.0T磁共振T2 mapping序列联合血清新饱食分子蛋白1水平检测在老年膝关节早期骨关节炎诊断中的应用价值
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作者 唐利 巩玉荣 +2 位作者 曾立叶 高艳芳 邓成哲 《实用医学杂志》 北大核心 2025年第8期1238-1242,共5页
目的探讨3.0 T磁共振(MRI)T2 mapping序列联合血清新饱食分子蛋白1(nesfatin-1)水平对老年膝关节早期骨关节炎(OA)的诊断价值。方法选取2023年5月至2024年5月医院收治的膝关节OA的97例老年患者(OA组)和52例同期老年体检者(对照组),根据... 目的探讨3.0 T磁共振(MRI)T2 mapping序列联合血清新饱食分子蛋白1(nesfatin-1)水平对老年膝关节早期骨关节炎(OA)的诊断价值。方法选取2023年5月至2024年5月医院收治的膝关节OA的97例老年患者(OA组)和52例同期老年体检者(对照组),根据X线结果将膝关节OA组分为早期组和非早期组,均接受3.0T MRI T2 mapping序列扫描检测膝关节软骨区域T2值,检测血清nesfatin-1水平,比较上述指标差异并采用ROC曲线分析其对老年膝关节早期OA的诊断价值。结果97例老年膝关节OA患者中,早期组35例,非早期组62例,OA组患者膝关节5个软骨区域的T2值及nesfatin-1血清均高于对照组(P<0.05),早期组均低于非早期组(P<0.05);膝关节软骨区域T2值和血清nesfatin-1水平单独诊断早期OA的AUC在0.774~0.871范围,联合诊断的AUC为0.939。结论3.0 T磁共振T2 mapping序列联合血清nesfatin-1水平检测对老年膝关节早期OA具有较高的诊断价值。 展开更多
关键词 膝关节早期骨关节炎 老年 磁共振 T2 mapping序列 新饱食分子蛋白1
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MR T_(1)-mapping结合动脉自旋标记技术在评估儿童慢性肾脏病肾纤维化和灌注中的应用 被引量:1
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作者 赵佳佳 胡俊 +2 位作者 尹传高 顾东浩 朱晓冬 《临床放射学杂志》 北大核心 2025年第3期513-517,共5页
目的初步研究MR纵向弛豫时间定量成像(T 1-mapping)和动脉自旋标记技术(ASL)在诊断儿童慢性肾脏病(CKD)中的应用价值。方法纳入CKD患儿32例(包括肾脏未萎缩19例,萎缩13例),同期招募健康志愿者30名作对照组,行T 1-mapping和ASL序列扫描,... 目的初步研究MR纵向弛豫时间定量成像(T 1-mapping)和动脉自旋标记技术(ASL)在诊断儿童慢性肾脏病(CKD)中的应用价值。方法纳入CKD患儿32例(包括肾脏未萎缩19例,萎缩13例),同期招募健康志愿者30名作对照组,行T 1-mapping和ASL序列扫描,分别获得肾皮质T 1值和肾皮质血流量(RBF)。比较对照组和CKD组患儿肾皮质T 1值和RBF值的差异,并分析CKD组肾皮质T 1值和RBF值与估算肾小球滤过率(eGFR)、血肌酐(Scr)、血胱抑素C(Cys-C)的相关性。结果CKD组较对照组肾皮质T 1值明显升高、RBF值明显减低(P<0.05);CKD组中,肾脏未萎缩患儿肾皮质T 1值与eGRF、Scr、Cys-C呈高、中度相关(r=-0.832、0.777、0.698,P<0.05),肾脏萎缩患儿肾皮质T 1值与eGRF、Scr呈高度相关(r=0.726、-0.743,P<0.05);CKD组肾皮质RBF与eGRF、Cys-C、Scr呈中度相关(r=0.699、-0.619、-0.554,P<0.05)。结论MR T_(1)-mapping和ASL定量反映肾脏微观病理变化及血流灌注情况,具有预测肾脏慢性病理损伤的潜在价值,有望在肾脏发生不可逆损伤前早期、无创地提供肾脏功能信息。 展开更多
关键词 慢性肾脏病 儿童 T_(1)-mapping 动脉自旋标记 磁共振功能成像
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High-definition colonoscopy with i-Scan:Better diagnosis for small polyps and flat adenomas 被引量:12
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作者 Pier Alberto Testoni Chiara Notaristefano +2 位作者 Cristian Vailati Milena Di Leo Edi Viale 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第37期5231-5239,共9页
AIM: To investigate if high-definition (HD) colonoscope with i-Scan gave a higher detection rate of mucosal le- sions vs standard white-light instruments. METHODS: Data were collected from the computer- ized datab... AIM: To investigate if high-definition (HD) colonoscope with i-Scan gave a higher detection rate of mucosal le- sions vs standard white-light instruments. METHODS: Data were collected from the computer- ized database of the endoscopy unit of our tertiary referral center. We retrospectively analyzed 1101 con- secutive colonoscopies that were performed over 1 year with standard white-light (n = 849) or HD+ with i-Scan (n = 252) instruments by four endoscopists, in an outpatient setting. Colonoscopy records included patients' main details and family history for colorectal cancer, indication for colonoscopy (screening, diagnos- tic or surveillance), type of instrument used (standard white-light or HD+ plus i-Scan), name of endoscopist and bowel preparation. Records for each procedure included whether the cecum was reached or not and the reason for failure, complications during or imme- diately after the procedure, and number, size, location and characteristics of the lesions. Polyps or protruding lesions were defined as sessile or pedunculated, and nonprotruding lesions were defined according to Paris classification. For each lesion, histological diagnosis was recorded. RESULTS: Eight hundred and forty-nine colonosco- pies were carried with the standard white-light video colonoscope and 252 with the HD+ plus i-Scan video colonoscope, The four endoscopists did 264, 300, 276 and 261 procedures, respectively; 21.6%, 24.0%, 21.7% and 24.1% of them with the HD+ plus i-Scan technique. There were no significant differences be- tween the four endoscopists in either the number of procedures done or the proportions of each imaging technique used. Both techniques detected one or more mucosal lesions in 522/1101 procedures (47.4%). The overall number of lesions recognized was 1266; 645 in the right colon and 621 in the left. A significantly higher number of colonoscopies recognized lesions in the HD+ plus i-Scan mode (171/252 = 67.9%) than with the standard white-light technique (408/849 = 48.1%) (P 〈 0.0001). HD+ with i-Scan colonoscopies identified more lesions than standard white-light imag- ing (459/252 and 807/849, P 〈 0.0001), in the right or left colon (mean :1: SD, 1.62±1.36 vs 1.33±0.73, P 〈 0.003 and 1.55±0.98 vs 1.17±0.93, P = 0.033), more lesions 〈 10 mm (P 〈 0.0001) or nonprotruding (P 〈 0.022), and flat polyps (P = 0.04). The cumulative mean number of lesions per procedure detected by the four endoscopists was significantly higher with HD+ with i-Scan than with standard white-light imaging (1.82 ± 2.89 vs 0.95± 1.35, P 〈 0.0001). CONCLUSION: HD imaging with i-Scan during the withdrawal phase of colonoscopy significantly increased the detection of colonic mucosal lesions, particularly small and nonprotruding polyps. 展开更多
关键词 COLONOSCOPY high-definition with i-Scancolonoscopy White-light colonoscopy Colonic polyps Nonprotruding lesions Adenoma detection rate With-drawal time Surface enhancement Contrast enhance-ment Tone enhancement
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Standard-definition White-light,High-definition White-light versus Narrow-band Imaging Endoscopy for Detecting Colorectal Adenomas:A Multicenter Randomized Controlled Trial 被引量:1
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作者 Chang-wei DUAN Hui-hong ZHAI +10 位作者 Hui XIE Xian-zong MA Dong-liang YU Lang YANG Xin WANG Yu-fen TANG Jie ZHANG Hui SU Jian-qiu SHENG Jun-feng XU Peng JIN 《Current Medical Science》 SCIE CAS 2024年第3期554-560,共7页
Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colore... Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colorectal lesions in the Chinese population.Methods This was a multicenter,single-blind,randomized,controlled trial with a non-inferiority design.Patients undergoing endoscopy for physical examination,screening,and surveillance were enrolled from July 2017 to December 2020.The primary outcome measure was the adenoma detection rate(ADR),defined as the proportion of patients with at least one adenoma detected.The associated factors for detecting adenomas were assessed using univariate and multivariate logistic regression.Results Out of 653 eligible patients enrolled,data from 596 patients were analyzed.The ADRs were 34.5%in the SD-WL group,33.5%in the HD-WL group,and 37.5%in the HD-NBI group(P=0.72).The advanced neoplasm detection rates(ANDRs)in the three arms were 17.1%,15.5%,and 10.4%(P=0.17).No significant differences were found between the SD group and HD group regarding ADR or ANDR(ADR:34.5%vs.35.6%,P=0.79;ANDR:17.1%vs.13.0%,P=0.16,respectively).Similar results were observed between the HD-WL group and HD-NBI group(ADR:33.5%vs.37.7%,P=0.45;ANDR:15.5%vs.10.4%,P=0.18,respectively).In the univariate and multivariate logistic regression analyses,neither HD-WL nor HD-NBI led to a significant difference in overall adenoma detection compared to SD-WL(HD-WL:OR 0.91,P=0.69;HD-NBI:OR 1.15,P=0.80).Conclusion HD-NBI and HD-WL are comparable to SD-WL for overall adenoma detection among Chinese outpatients.It can be concluded that HD-NBI or HD-WL is not superior to SD-WL,but more effective instruction may be needed to guide the selection of different endoscopic methods in the future.Our study’s conclusions may aid in the efficient allocation and utilization of limited colonoscopy resources,especially advanced imaging technologies. 展开更多
关键词 standard-definition white-light endoscopy high-definition white-light endoscopy narrow-band imaging colonoscopy colorectal cancer screening adenoma detection rate
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基于ArcMap的森林资源调查地形图接图网制作
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作者 胡卫东 龙艳 《计算机应用文摘》 2025年第9期176-179,182,共5页
文章以广西森林资源调查1∶1万地形图接图网的制作过程为例,利用ArcMap 10.8的渔网工具、创建自定义地理(坐标)变换工具和投影工具,制作了基于CGCS2000坐标系的1∶1万地形图接图网,以及1954北京坐标系转CGCS2000坐标系和1980西安坐标系... 文章以广西森林资源调查1∶1万地形图接图网的制作过程为例,利用ArcMap 10.8的渔网工具、创建自定义地理(坐标)变换工具和投影工具,制作了基于CGCS2000坐标系的1∶1万地形图接图网,以及1954北京坐标系转CGCS2000坐标系和1980西安坐标系转CGCS2000坐标系的1∶1万地形图接图网,旨在通过接图网,在CGCS2000坐标系下,快速、准确、高效地完成不同坐标系下的1∶1万地形图栅格配准。 展开更多
关键词 森林资源调查 ARCmap 地形图 接图网 配准
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Residual Attention-BiConvLSTM:一种新的全球电离层TEC map预测模型 被引量:1
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作者 王浩然 刘海军 +5 位作者 袁静 乐会军 李良超 陈羿 单维锋 袁国铭 《地球物理学报》 北大核心 2025年第2期413-430,共18页
电离层总电子含量(TEC)预测对提高全球卫星导航系统(GNSS)的精度具有重要意义.现有的TEC map预测模型主要通过顺序堆叠时空特征提取单元来实现.这种模型搭建方法会因多个卷积层顺序堆叠而损失细粒度的TEC map的空间特征,导致模型精度不... 电离层总电子含量(TEC)预测对提高全球卫星导航系统(GNSS)的精度具有重要意义.现有的TEC map预测模型主要通过顺序堆叠时空特征提取单元来实现.这种模型搭建方法会因多个卷积层顺序堆叠而损失细粒度的TEC map的空间特征,导致模型精度不够;还会由于多层堆叠导致梯度消失或梯度爆炸问题.本文借鉴残差注意力(Residual Attention)的思想,在TEC map预测模型中增加了残差注意力模块,提出了Residual Attention-BiConvLSTM模型.该模型中的残差注意力模块能同时提取粗、细粒度空间特征,并对其进行加权.本文在全球TEC map数据上与ConvLSTM、ConvGRU、ED-ConvLSTM和C1PG进行了对比实验.实验结果表明,本文所提出的Residual Attention-BiConvLSTM模型的RMSE、MAE、MAPE和R^(2)在太阳活动高年和年均优于对比模型.本文还在一次磁暴事件中对比了5种模型的预测效果.实验结果表明,大磁暴发生时,本文模型与C1PG相近,优于其他3种对比模型.本文的研究工作为电离层map预测模型搭建提供一个新思路. 展开更多
关键词 电离层TEC map预测 残差注意力模块 Residual Attention-BiConvLSTM 时空预测模型
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基于磁共振T1 mapping影像组学胰腺导管腺癌间质比定量评估模型的开发与临床验证
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作者 张心悦 陈成伟 +4 位作者 袁小涵 沈奕暄 陈士跃 边云 陆建平 《海军军医大学学报》 北大核心 2025年第12期1597-1603,共7页
目的开发基于MRI T1 mapping影像组学的胰腺导管腺癌(PDAC)间质含量无创评估模型。方法前瞻性纳入2023年6月至2024年12月海军军医大学第一附属医院157例经术后病理确诊的PDAC患者。从T1 mapping图像提取12442个特征并筛选出10个关键特征... 目的开发基于MRI T1 mapping影像组学的胰腺导管腺癌(PDAC)间质含量无创评估模型。方法前瞻性纳入2023年6月至2024年12月海军军医大学第一附属医院157例经术后病理确诊的PDAC患者。从T1 mapping图像提取12442个特征并筛选出10个关键特征,采用最小绝对收缩和选择算子回归对10个关键特征进行线性组合及加权计算,得到影像组学评分(Rad_Score)。采用Spearman秩相关检验Rad_Score与间质含量的相关性。以病理诊断的间质含量为金标准,通过ROC曲线评估Rad_Score的诊断效能。采用多重线性回归建立间质含量预测方程(纳入Rad_Score与肿瘤最大径),采用Bland-Altman法检验预测值与实际值的一致性。结果在PADC患者中Rad_Score与间质含量相关(rs=0.52,P<0.001),Rad_Score预测间质含量>0.5的AUC值为0.936(95%CI 0.885~0.987)、灵敏度为91.7%、特异度为88.0%。基于Rad_Score和肿瘤最大径构建的线性回归预测模型为:间质含量=0.592+0.037×Rad_Score-0.025×肿瘤最大径(cm);Bland-Altman法分析显示其预测的间质含量与实际值一致性较好(平均偏差为0.00,95%一致性界限为-0.33~0.33)。结论基于MRI T1 mapping影像组学建立的PDAC间质评估模型对高、低间质含量有较好的区分价值。 展开更多
关键词 磁共振成像 T1 mapping 胰腺导管腺癌 间质比 影像组学 深度学习 多模态 无创评估
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酰胺质子转移加权成像及T2 mapping成像对子宫内膜样腺癌微卫星不稳定状态的预测价值
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作者 程连华 常玲玉 +3 位作者 于德新 王青 贾进正 王芳 《中国医学科学院学报》 北大核心 2025年第6期947-953,共7页
目的探讨酰胺质子转移加权成像(APTw)及T2 mapping在评估子宫内膜样腺癌微卫星不稳定性(MSI)的价值。方法前瞻性纳入临床疑似为子宫内膜癌的患者,所有患者术前均行APTw及T2 mapping成像。两名放射科医师分别行感兴趣区的勾画及定量参数... 目的探讨酰胺质子转移加权成像(APTw)及T2 mapping在评估子宫内膜样腺癌微卫星不稳定性(MSI)的价值。方法前瞻性纳入临床疑似为子宫内膜癌的患者,所有患者术前均行APTw及T2 mapping成像。两名放射科医师分别行感兴趣区的勾画及定量参数的测量。经组内相关系数检验两位医师所测MRI参数值的一致性;采用独立样本t检验或者Mann-Whitney U检验比较MSI组与微卫星稳定(MSS)组之间定量参数的差异;经受试者工作特征曲线评估各序列的诊断效能;采用DeLong检验比较单一参数及联合序列之间曲线下面积(AUC)的差异。结果共纳入MSI组患者21例,MSS组患者37例。两名医师所测结果一致性好。MSI组APTw值显著高于MSS组[(2.72±0.52)%比(2.08±0.39)%,P<0.001];T2值显著低于MSS组[92.25(90.82,99.91)ms比101.80(96.15,112.13)ms,P<0.001]。受试者工作特征曲线显示APTw、T2 mapping序列的AUC值分别为0.821(95%CI=0.698~0.909)、0.793(95%CI=0.666~0.888),两种序列的诊断效能差异无统计学意义(P=0.692);当两序列联合时,AUC值提高至0.897(95%CI=0.789~0.961),较单一APTw及T2 mapping序列的诊断效能均显著提高(P=0.042,P=0.025)。结论APTw及T2 mapping成像在评估子宫内膜样腺癌患者MSI状态方面具有一定的临床价值,两者联合显示出更高的诊断效能,为患者术前治疗方式的选择提供有效依据。 展开更多
关键词 子宫内膜样腺癌 酰胺质子转移加权成像 T2 mapping 微卫星不稳定性
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重新联结生活世界:詹姆斯·科纳Mapping理论的批判性实践 被引量:1
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作者 陈永明 周启明 《建筑师》 2025年第2期100-110,共11页
詹姆斯·科纳的Mapping理论一直备受学界的高度关注。本文围绕科纳在Mapping理论探索中对“具身性感知”与“理性测量”的反思,厘清Mapping中“批判性实践”的理论内涵,并指出其在智识性的思辨和想象性的建构两个方面所展开的理论... 詹姆斯·科纳的Mapping理论一直备受学界的高度关注。本文围绕科纳在Mapping理论探索中对“具身性感知”与“理性测量”的反思,厘清Mapping中“批判性实践”的理论内涵,并指出其在智识性的思辨和想象性的建构两个方面所展开的理论逻辑。随后以科纳的霍皮人天气日历、十的次方和西雅图海滨公园设计等三个作品为例,阐述了Mapping操作的方法和特征,以及其对重新联结生活世界的价值和启示。 展开更多
关键词 mapPING 批判性实践 复合性操作 具身性 日常生活 诗意
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Optical diagnosis of colorectal polyps using high-definition i-scan: An educational experience
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作者 Mariёlle WE Bouwens Rogier de Ridder +4 位作者 Ad AM Masclee Ann Driessen Robert G Riedl Bjorn Winkens Silvia Sanduleanu 《World Journal of Gastroenterology》 SCIE CAS 2013年第27期4334-4343,共10页
AIM:To examine performances regarding prediction of polyp histology using high-definition (HD) i-scan in a group of endoscopists with varying levels of experience. METHODS:We used a digital library of HD i-scan still ... AIM:To examine performances regarding prediction of polyp histology using high-definition (HD) i-scan in a group of endoscopists with varying levels of experience. METHODS:We used a digital library of HD i-scan still images, comprising twin pictures (surface enhancement and tone enhancement), collected at our university hospital. We defined endoscopic features of adenomatous and non-adenomatous polyps, according to the following parameters:color, surface pattern and vascular pattern. We familiarized the participating endoscopists on optical diagnosis of colorectal polyps using a 20-min didactic training session. All endoscopists were asked to evaluate an image set of 50 colorectal polyps with regard to polyp histology. We classified the diagnoses into high confidence (i.e., cases in which the endoscopist could assign a diagnosis with certainty) and low confidence diagnoses (i.e., cases in which the endoscopist preferred to send the polyp for formal histology). Mean sensitivity, specificity and accuracy per endoscopist/image were computed and differences between groups tested using independent-samples t tests. High vs low confidence diagnoses were compared using the pairedsamples t test. RESULTS:Eleven endoscopists without previous experience on optical diagnosis evaluated a total of 550 images (396 adenomatous, 154 non-adenomatous). Mean sensitivity, specificity and accuracy for diagnosing adenomas were 79.3%, 85.7% and 81.1%, respectively. No significant differences were found between gastroenterologists and trainees regarding performances of optical diagnosis (mean accuracy 78.0%vs 82.9%,P = 0.098). Diminutive lesions were predicted with a lower mean accuracy as compared to non-diminutive lesions (74.2% vs 93.1%, P = 0.008). A total of 446 (81.1%) diagnoses were made with high confidence. High confidence diagnoses corresponded to a significantly higher mean accuracy than low confidence diagnoses (84.0% vs 64.3%, P = 0.008). A total of 319 (58.0%) images were evaluated as having excellent quality. Considering excellent quality images in conjunction with high confidence diagnosis, overall accuracy increased to 92.8%. CONCLUSION:After a single training session, endoscopists with varying levels of experience can already provide optical diagnosis with an accuracy of 84.0%. 展开更多
关键词 COLONOSCOPY high-definition i-scan Optical diagnosis Colorectal POLYPS Training
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基于T_(2)mapping及超短回波时间技术定量探究早期膝骨关节炎的发病机制 被引量:2
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作者 牛飞格 孟祥虹 +1 位作者 孙曼 王植 《临床放射学杂志》 北大核心 2025年第2期350-356,共7页
目的基于浅表软骨的T_(2)mapping和骨软骨交界区(OCJ)的超短回波时间(UTE)T_(2)^(*)mapping探究膝骨关节炎(KOA)早期浅表软骨和骨软骨交界区的病变顺序。方法对纳入的30个健康膝和30个早期骨性关节炎膝进行常规和定量MRI扫描,主要扫描... 目的基于浅表软骨的T_(2)mapping和骨软骨交界区(OCJ)的超短回波时间(UTE)T_(2)^(*)mapping探究膝骨关节炎(KOA)早期浅表软骨和骨软骨交界区的病变顺序。方法对纳入的30个健康膝和30个早期骨性关节炎膝进行常规和定量MRI扫描,主要扫描序列包括三维水激发序列(3D WATS)、T_(2)mapping和UTE T_(2)^(*)mapping。将每个膝关节都分为股骨内侧髁、股骨外侧髁、胫骨内侧髁、胫骨外侧髁、髌骨和滑车区6个区域并测量每个区域的浅层软骨T_(2)值和OCJ T_(2)^(*)值。用独立样本t检验比较健康组和早期KOA组间的浅层软骨T_(2)值及OCJ T_(2)^(*)值。用Spearman相关性检验评估浅层软骨T_(2)值与OCJ T_(2)^(*)值间的相关性。结果早期KOA组的浅层软骨T_(2)值在股骨内侧髁(P<0.001)、胫骨内侧平台(P<0.001)、髌骨(P<0.001)和股骨滑车区(P=0.01)相对于健康组显著升高。早期KOA组OCJ T_(2)^(*)值在股骨内侧髁(P<0.001)、胫骨内侧平台(P<0.001)、胫骨外侧平台(P<0.001)、髌骨(P=0.001)和滑车区(P<0.001)均显著升高。浅层软骨T_(2)值和骨软骨交界区T_(2)^(*)值间存在正相关关系(r=0.37,P<0.001)。结论浅表软骨的T_(2)mapping和骨软骨交界区的UTE T_(2)^(*)mapping成像都可定量且无创识别早期KOA。在KOA早期,浅表软骨和OCJ都出现了生化改变。 展开更多
关键词 骨性关节炎 关节软骨骨软骨交界区 T_(2)mapping T_(2)^(*)mapping
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基于副结核分枝杆菌重组MAP0827c蛋白的间接ELISA抗体检测方法的建立与初步应用 被引量:1
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作者 俞杰 许淑芸 +3 位作者 魏京京 魏增科 赵昌乐 周霞 《中国预防兽医学报》 北大核心 2025年第3期271-277,共7页
为建立快速准确检测副结核分枝杆菌(MAP)抗体的间接ELISA方法,本研究通过SignalP-5.0等相关网站分析MAP0827c蛋白的生物信息学特点,设计扩增MAP MAP0827c基因的引物,将扩增的MAP0827c基因克隆于pET-32a(+)中构建重组质粒pET32a-MAP0827c... 为建立快速准确检测副结核分枝杆菌(MAP)抗体的间接ELISA方法,本研究通过SignalP-5.0等相关网站分析MAP0827c蛋白的生物信息学特点,设计扩增MAP MAP0827c基因的引物,将扩增的MAP0827c基因克隆于pET-32a(+)中构建重组质粒pET32a-MAP0827c,并经酶切和测序鉴定正确后利用原核表达系统表达重组MAP0827c蛋白,以该蛋白作为包被抗原,采用棋盘滴定法筛选间接ELISA反应条件,确定临界值,以异源阳性血清验证该方法的特异性;通过稀释阳性血清评估所建方法的灵敏性;以5份牛MAP阳性血清进行该方法的批内和批间试验评估该方法的重复性。结果显示,MAP0827c蛋白由374个氨基酸构成,含15个抗原决定簇,不存在跨膜区和信号肽,二级结构以α螺旋为主。经原核系统表达了分子量为42 ku的目的蛋白。建立的ELISA方法蛋白最佳包被量为0.05μg/mL,一抗血清最佳稀释倍数为1:100,二抗兔抗牛IgG-HRP的最佳稀释倍数为1:5000,封闭液选择1%明胶封闭1 h,一抗血清作用时为1 h,酶标二抗孵育时间为1 h,显色时间为25 min;特异性试验结果显示,建立的间接ELISA方法仅对MAP阳性血清检测为阳性,而不与布鲁氏菌、结核分枝杆菌及金黄色葡萄球菌的牛阳性血清发生反应,特异性强;敏感性试验结果显示,可检测的阳性血清最大稀释度为1:800,敏感性高;批内和批间重复试验结果显示,变异系数均小于10%,重复性较好。采用建立的ELISA方法和商品化ELISA试剂盒对70份临床牛血清样品进行检测,结果显示,二者的阳性检出率分别为30%(21/70)和34.29%(24/70),二者的总符合率为95.71%。本研究首次建立了基于MAP0827c蛋白的检测MAP抗体的间接ELISA方法,为MAP流行病学调查和检测提供了可行技术手段。 展开更多
关键词 副结核分枝杆菌 map0827c蛋白 原核表达 抗体 间接ELISA
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磁共振T2-mapping成像技术在膝关节骨性关节炎诊断中应用的研究进展
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作者 陈思 《黑龙江医学》 2025年第16期2042-2044,2048,共4页
T2-mapping成像技术通过分析软骨的T2弛豫时间,定量评估软骨组织学结构,揭示软骨中水含量和胶原纤维排列的变化,适用于早期检测软骨损伤和监测疾病进展,对评估软骨健康状况至关重要。T2-mapping成像技术不仅对膝关节骨性关节炎(KOA)的... T2-mapping成像技术通过分析软骨的T2弛豫时间,定量评估软骨组织学结构,揭示软骨中水含量和胶原纤维排列的变化,适用于早期检测软骨损伤和监测疾病进展,对评估软骨健康状况至关重要。T2-mapping成像技术不仅对膝关节骨性关节炎(KOA)的早期诊断和进展监测具有重要价值,还能在软骨修复过程中监测和评估软骨的生化变化。随着成像技术和数据处理能力的进一步发展,T2-mapping成像有望提高诊断精度、优化治疗方案,为KOA的管理和治疗带来革新。文章综述了磁共振成像技术(MRI)中的T2-mapping成像技术在KOA诊断和评估中的应用。 展开更多
关键词 磁共振T2-mapping成像 膝关节 骨性关节炎
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基于T2^(*)mapping的业余马拉松运动员足踝部关节软骨损伤及其影响因素分析 被引量:2
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作者 高雅丽 兰晓川 +2 位作者 王舒 宋凌恒 陈伟 《磁共振成像》 北大核心 2025年第2期94-99,共6页
目的基于T2^(*)mapping定量分析业余马拉松运动员足踝部关节软骨的T2^(*)值,并分析其与性别、年龄、身体质量指数(body mass index,BMI)、跑龄、跑量之间的相关性。材料与方法于2023年7月份至2023年9月份招募重庆市长跑运动爱好者48名,... 目的基于T2^(*)mapping定量分析业余马拉松运动员足踝部关节软骨的T2^(*)值,并分析其与性别、年龄、身体质量指数(body mass index,BMI)、跑龄、跑量之间的相关性。材料与方法于2023年7月份至2023年9月份招募重庆市长跑运动爱好者48名,其中跑量<300 km/月的36例(中低跑量组),跑量≥300 km/月的12例(高跑量组)。所有受试者均进行单侧无症状踝关节的MRI扫描,扫描序列包括T2^(*)mapping多回波自旋回波(spin echo,SE)序列矢状位、质子密度加权成像脂肪抑制(proton density-weighted imaging fat-saturated,PDWI-FS)序列矢状位、冠状位、横轴位以及T1加权脂肪抑制成像(T1-weighted imaging fat-saturated,T1WI-FS)序列横轴位。沿关节软骨轮廓边缘勾画距骨穹窿、跟骰关节跟骨面、骰骨面及后距下关节跟骨面、距骨面软骨作为感兴趣区(region of interest,ROI),获得相应的T2^(*)值。采用线性回归分析软骨T2^(*)值与年龄、BMI、跑龄的相关性,采用独立样本t检验分析不同跑量及不同性别间的软骨T2^(*)值差异。结果(1)距骨穹窿、跟骰关节跟骨面及骰骨面、后距下关节跟骨面及距骨面软骨T2^(*)值在性别上的差异均具有统计学意义(P=0.001、P<0.001、P=0.002、P=0.008、P=0.004);(2)高跑量组的距骨穹窿、后距下关节跟骨面软骨T2^(*)值高于中低跑量组(P=0.014、0.023),不同跑量的跟骰关节跟骨面及骰骨面、后距下关节距骨面软骨T2^(*)值的差异均无统计学意义(P=0.987、0.072、0.724);(3)距骨穹窿、跟骰关节跟骨面及骰骨面、后距下关节跟骨面、距骨面软骨T2^(*)值均与BMI呈正相关(r=0.376、0.384、0.300、0.422、0.455,P=0.005、0.004、0.019、0.001、0.001)。结论在业余马拉松运动员这一跑步群体中,与中低跑量相比,高跑量更有可能导致距骨穹窿、后距下关节跟骨面软骨损伤;而与较低的BMI相比,高BMI增加了距骨穹窿、跟骰关节跟骨面、骰骨面及后距下关节跟骨面、距骨面软骨损伤的风险。 展开更多
关键词 业余马拉松 跑步 软骨 磁共振成像 T2^(*)mapping
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A Reliable Adaptive High-Definition Transmission System for Distance Learning
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作者 徐奇 李鹤廷 《Journal of Shanghai Jiaotong university(Science)》 EI 2007年第6期740-743,共4页
There is an increasing demand for supporting high-quality real-time audiovisual services for the next generation wired and wireless networks. However, due to variety of bandwidths of different networks, it is a great ... There is an increasing demand for supporting high-quality real-time audiovisual services for the next generation wired and wireless networks. However, due to variety of bandwidths of different networks, it is a great challenge for deployment. In this paper, a novel high-definition (HD) video transmission system was proposed which depends upon reliable compound multicast protocols and QoS control over the various kinds of networks. This system detects client's network condition and assigns it to a proper proxy. Each proxy is capable of detecting network parameters and adaptively tuning such transport parameters as bit rate, video resolution, frame rate and QoS mechanisms to this condition. It also provides FEC error recovery under consideration of characteristics of MPEG4 video codec. Our simulation demonstrates that different network clients such as ADSL, CERNET, and CERNET2 can receive more video reliability with less delay. 展开更多
关键词 ADAPTIVE high-definition(HD) transmission system distance learning RELIABLE compound MULTICAST protocol (RCMP)
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