Objective:To examine the change in COVID-19 booster vaccine hesitancy according to descriptive characteristics,characteristics related to COVID-19,health literacy(HL)skills related to booster dose.Methods:The inclusio...Objective:To examine the change in COVID-19 booster vaccine hesitancy according to descriptive characteristics,characteristics related to COVID-19,health literacy(HL)skills related to booster dose.Methods:The inclusion criterion was the completion of the primary scheme as two doses of COVID-19 vaccine.The study was conducted in January 2022 by applying face-to-face interview technique.Questions regarding HL were used to question the ability of individuals to access,understand,interpret and use information regarding the COVID-19 booster dose in their decisions.Results:A total of 1210 people were included in this study with an mean age of(41.3±16.6)years,and 51.4%were women.In multivariate analysis,hesitation increased in the"moderately concerned"(aOR 2.65,95%CI 1.09-6.45),"slightly concerned"(aOR 3.01,95%CI 1.26-7.19),"not concerned at all”(aOR 5.69,95%CI 2.27-14.28)groups compared to the group“extremely concerned”about COVID-19 transmission.Those with Sinovac-CoronaVac as their most recent vaccine had increased hesitation compared to those with Pfizer-BioNTech(aOR 3.68,95%CI 2.05-6.61).The effect of HL skills including“accessing”,“understanding”,and“appraising”information on hesitation was not statistically significant(P>0.05).HL skill of“applying”was assessed with ability of information to help decision making.Whether the information is helpful for decision-making,the risk of hesitancy increased for those who stated that it"sometimes helps"(aOR 2.55;95%CI 1.31-4.99)and"never helps"(aOR 11.62;95%CI 3.03-44.58)compared to those who stated that it"always helps".Conclusions:The increased propability of hesitation in those less concerned about COVID-19 transmission shows the importance of appropriately guiding individuals'concern levels with a health communication strategy based on risk communication.The fact that the only HL skill with a significant effect in the multivariate model was“applying”,shows the critical role of this skill in influencing behavioral changes.展开更多
Background:Vaccine hesitancy remains a pressing global challenge,impacting the acceptance and distribution of both long-established and newly developed vaccines.This paper investigates the multifaceted nature of vacci...Background:Vaccine hesitancy remains a pressing global challenge,impacting the acceptance and distribution of both long-established and newly developed vaccines.This paper investigates the multifaceted nature of vaccine hesitancy,focusing on the development of the measles vaccine as a historical case study,while drawing comparisons to the coronavirus disease 2019(COVID-19)pandemic.Methods:The study employs a historical and comparative approach to analyze vaccine hesitancy.It examines how technological advances,public policy,and communication strategies have influenced vaccine acceptance.Key lessons from the development of the measles vaccine are compared with challenges encountered during the rapid development and deployment of COVID-19 vaccines.Results:Both historical and contemporary examples reveal commonalities and differences in addressing vaccine hesitancy.While the measles vaccine demonstrated the importance of long-term safety evaluations and public trust-building,the COVID-19 vaccine highlighted the challenges of rapid development timelines and combating misinformation in a digital age.The findings underscore the necessity of transparent communication,equitable access,and proactive engagement in overcoming hesitancy.Conclusion:Understanding the historical and contemporary dynamics of vaccine hesitancy is crucial for promoting public trust and equitable vaccination in an evolving global health landscape.Effective strategies,combining historical lessons with modern innovations,can address public concerns and enhance vaccine acceptance.展开更多
Bacckground:Based on the 3C model,this study explores the current situation of HPV vaccine hesitancy among women of childbearing age and the factors influencing vaccine hesitancy.Methods:Based on the free cervical can...Bacckground:Based on the 3C model,this study explores the current situation of HPV vaccine hesitancy among women of childbearing age and the factors influencing vaccine hesitancy.Methods:Based on the free cervical cancer screening project in Baoan District,this study designed a questionnaire under the framework of vaccine hesitation 3C theory and carried out a self-filling electronic questionnaire survey among women of childbearing age.Results:The rate of HPV vaccination awareness among women of childbearing age in Bao’an District was 93.25%.HPV vaccine acceptance reached 71.55%,and 24.59%of the survey respondents experienced HPV vaccine hesitation,a high percentage of whom were hesitant.The influencing factors of HPV vaccine hesitation among women of childbearing age were perceived necessity of HPV vaccination(0.482),no one around them receiving the HPV vaccine(0.411),perception of the price of the vaccine(0.354),degree of trust in the safety of the vaccine(0.223),and degree of concern about the HPV vaccine(0.153).Conclusion:The 3C model can be used for the study of HPV vaccine hesitancy.Strengthening the publicity of HPV vaccination and improving women’s knowledge of the HPV vaccine can reduce their hesitation toward HPV vaccination.展开更多
Introduction: The coronavirus disease 2019 (COVID-19) is an infectious disease of the respiratory tract caused by SARS-CoV-2. Since its emergence, there have been increased rates of transmission and spread, morbidity ...Introduction: The coronavirus disease 2019 (COVID-19) is an infectious disease of the respiratory tract caused by SARS-CoV-2. Since its emergence, there have been increased rates of transmission and spread, morbidity and mortality which led to the development of COVID-19 vaccines to address the pandemic. This study assessed acceptance, knowledge, attitude, and perceived risks regarding COVID-19 vaccines among pregnant women attending antenatal care at two First-Level Hospitals in Lusaka, Zambia. Materials and Methods: This was a cross-sectional study that was conducted among 241 pregnant women using a questionnaire from August 2023 to October 2023 in two First-Level Hospitals in Lusaka district, Zambia. The collected data were analyzed using IBM Statistical Package for Social Sciences (SPSS) version 22.0. Statistical analysis was performed using a Chi-square test. The statistical significance was set at a 95% confidence level. Results: Of the 241 participants, 107 (42.7%) were aged between 24 and 34 years. Overall, 64.3% accepted the COVID-19 vaccines, of which 122 (50.6%) were already vaccinated. Further, 203 (84.6%) of the pregnant women had good knowledge, and 199 (82.6%) had positive attitudes towards COVID-19 vaccines. However, 58.5% thought COVID-19 vaccines were not safe and could cause infertility. Alongside this, 70.1% thought that COVID-19 vaccines were harmful during pregnancy. Having good knowledge of COVID-19 vaccines was associated with age (p = 0.049), education status (p = 0.001), and employment status (p = 0.001). Having a positive attitude towards COVID-19 vaccines was associated with education status (p = 0.001) and employment status (p = 0.001). Conclusion: This study found that most pregnant women had good knowledge, and positive attitudes, and the majority accepted the COVID-19 vaccine. Encouragingly, most of the pregnant women who accepted the COVID-19 vaccines were already vaccinated. Most pregnant women thought that COVID-19 vaccines had side effects, were not safe, and could be harmful during pregnancy. Consequently, this could have contributed to the hesitancy to receive a vaccine among some participants. The findings of this study demonstrate the need to provide pregnant women with continuous educational programs on the benefits of vaccinations for themselves and their children.展开更多
Perceptions of vaccine safety, importance and effectiveness are at the core of vaccine hesitancy around the world, and Africa has had its own share of vaccine revolts. This study uses the 2018 Wellcome Global Monitor ...Perceptions of vaccine safety, importance and effectiveness are at the core of vaccine hesitancy around the world, and Africa has had its own share of vaccine revolts. This study uses the 2018 Wellcome Global Monitor on public perceptions of vaccines in 40 African countries to examine the predictors of vaccine hesitancy.It examines levels of hesitancy from a language perspective, comparing French speakers with others, mostly English speakers. Results show that French speakers were significantly more hesitant about importance and safety, while English speakers and others were more hesitant about effectiveness. This reflects the continuing influence of colonial ties on African countries. Respondents with high levels of trust in social actors(such as national government, journalists, people neighborhood, doctors and nurses) were also more hesitant about the safety and effectiveness of vaccines, indicating the importance of non-scientists in influencing vaccine hesitancy. Those with high levels of education were more likely to be hesitant about vaccines in general, indicating that having more education may have an opposite effect. Perception of science as progress was significant for all three hesitancy types, indicating that Africans with more progressive attitudes were less likely to worry about the importance, safety and effectiveness of vaccines. At the country level, there was no overarching predictor, indicating the strong role of local social and cultural factors.These findings improve our understanding of the drivers of vaccine hesitancy in Africa and provide valuable input for future vaccine policy and health-awareness campaigns.展开更多
The hesitancy fuzzy graphs(HFGs),an extension of fuzzy graphs,are useful tools for dealing with ambiguity and uncertainty in issues involving decision-making(DM).This research implements a correlation coefficient meas...The hesitancy fuzzy graphs(HFGs),an extension of fuzzy graphs,are useful tools for dealing with ambiguity and uncertainty in issues involving decision-making(DM).This research implements a correlation coefficient measure(CCM)to assess the strength of the association between HFGs in this article since CCMs have a high capacity to process and interpret data.The CCM that is proposed between the HFGs has better qualities than the existing ones.It lowers restrictions on the hesitant fuzzy elements’length and may be used to establish whether the HFGs are connected negatively or favorably.Additionally,a CCMbased attribute DM approach is built into a hesitant fuzzy environment.This article suggests the use of weighted correlation coefficient measures(WCCMs)using the CCM concept to quantify the correlation between two HFGs.The decisionmaking problems of hesitancy fuzzy preference relations(HFPRs)are considered.This research proposes a new technique for assessing the relative weights of experts based on the uncertainty of HFPRs and the correlation coefficient degree of each HFPR.This paper determines the ranking order of all alternatives and the best one by using the CCMs between each option and the ideal choice.In the meantime,the appropriate example is given to demonstrate the viability of the new strategies.展开更多
BACKGROUND The coronavirus disease 2019(COVID-19)pandemic posed new challenges in patient care worldwide.Vaccinations,which have proven efficacious in lowering the COVID-19 hospital burden,are still avoided by large p...BACKGROUND The coronavirus disease 2019(COVID-19)pandemic posed new challenges in patient care worldwide.Vaccinations,which have proven efficacious in lowering the COVID-19 hospital burden,are still avoided by large populations.We,therefore,hypothesized that hospital care teams would have worse perceptions regarding the characteristics and care of patients with vaccine hesitancy.AIM To evaluate whether patient vaccine hesitancy affected the hospital care team(HCT)perceptions.METHODS We performed a prospective clinical study using structured questionnaires.We approached physicians and nurses with previous experience caring for COVID-19patients from 11 medical centers across Israel during the fourth COVID-19 surge(September and October 2021).The participants completed a questionnaire with the following parts:(1)Sociodemographic characteristics;(2)Assessment of anger(STAXI instrument)and chronic workplace stress(Shirom-Melamed burnout measure);and(3)Three tools to assess the effect of patient vaccine hesitancy on the HCT perceptions(the difficult doctor-patient relation questionnaire,the medical staff perception of patient’s responsibility questionnaire and the characterological derogation questionnaire).Results were evaluated according to each part of the questionnaire and the questionnaire as a whole.Associations between HCT perceptions and their baseline characteristics,anger or chronic workplace stress were assessed.RESULTS The HCT experienced their relationship with unvaccinated patients as more difficult(P<0.001,Cohen’s d=0.85),perceived unvaccinated patients as responsible for their medical condition(P<0.001,d=1.39)and perceived vaccinated patients as having a higher character value(P<0.001,d=1.03).Unvaccinated patients were considered selfish(P<0.001),less mature(P<0.001)and less satisfying to care for(P<0.001).The relationship with unvaccinated patients was more difficult among HCT with higher burnout(r=0.37,n=66,P=0.002).No correlations with baseline characteristics were found.All three study tools showed high internal consistency(αbetween 0.72 and 0.845).CONCLUSION Our results should raise awareness of the possible effects of vaccine hesitancy on HCT perceptions regarding unvaccinated patients.In order to minimize the potential negative impact on patient care,designated departments should promote specific patient-centered preparations.Further investigations should assess whether vaccine hesitancy directly affects patient quality of care.展开更多
Objective:To examine the pattern of COVID-19 infection and vaccination,and to explore pregnant women’s willingness and reluctance to accept a booster dose of the COVID-19 vaccine.Methods:This was a cross-sectional,de...Objective:To examine the pattern of COVID-19 infection and vaccination,and to explore pregnant women’s willingness and reluctance to accept a booster dose of the COVID-19 vaccine.Methods:This was a cross-sectional,descriptive study with a convenient sample size using a structured questionnaire among pregnant women attending the gynecology and obstetrics department at Acıbadem Mehmet Ali Aydinlar Hospital,Istanbul,Türkiye.The Health Belief Model scale was used to assess the intention and reluctance to accept a booster dose of the COVID-19 vaccine.Results:A total of 145 participants,with a mean age of(33.5±4.8)years,and a gestational age of(30.9±7.3)weeks,were enrolled in this study.88.8%Received full doses of the Pfizer-BioNTech vaccination.47.8%Participants suffered from vaccine adverse effects.Health Belief Model demonstrated a significant finding of perceived susceptibility(P<0.001),perceived severity of COVID-19 complications(P<0.001),and perceived benefits regarding a booster COVID-19 vaccination(P<0.001).Conclusions:Most pregnant women who received the COVID-19 immunization express a significant intention to receive a booster dose,regardless of the adverse effects experienced from the previous doses.However,a small percentage of the study sample express hesitancy about receiving the booster dose.展开更多
Diabetes mellitus is one of the most common comorbid conditions encountered in patients with severe acute respiratory syndrome coronavirus 2 infection accompanied by significantly increased mortality,prolonged hospita...Diabetes mellitus is one of the most common comorbid conditions encountered in patients with severe acute respiratory syndrome coronavirus 2 infection accompanied by significantly increased mortality,prolonged hospital stay,and requirement of invasive mechanical ventilation.This review aims to present the effectiveness and safety profile of available coronavirus disease 2019(COVID-19)vaccines in people with diabetes as a potential cause of hesitancy for vaccination.Data from published research proves a robust immune response following immunization for COVID-19 in diabetic patients with substantial production of virus-neutralizing antibodies;however,the observed immune response was unequivocally weaker than that in individuals without diabetes.This observation was further enhanced by the findings that worse glycemic control was associated with more suppressed antibody production.In contrast,individuals with optimal glycemic control performed similarly to healthy controls.In addition to the need for strict glucose monitoring and adequate diabetes treatment,those findings reinforce the concept of diabetes-induced secondary immune deficiency and necessitate the application of booster doses to diabetic patients with priority.Nevertheless,after vaccination,reported adverse events were not different from those in the general population.No increase in severe adverse events was documented.While single case reports detected transient increases in blood glucose post-vaccination,more extensive trials could not replicate such a relationship.展开更多
Decision-making(DM)is a process in which several persons concur-rently engage,examine the problems,evaluate potential alternatives,and select an appropriate option to the problem.Technique for determining order prefer...Decision-making(DM)is a process in which several persons concur-rently engage,examine the problems,evaluate potential alternatives,and select an appropriate option to the problem.Technique for determining order preference by similarity to the ideal solution(TOPSIS)is an established DM process.The objective of this report happens to broaden the approach of TOPSIS to solve the DM issues designed with Hesitancy fuzzy data,in which evaluation evidence given by the experts on possible solutions is presents as Hesitancy fuzzy decision matrices,each of which is defined by Hesitancy fuzzy numbers.Findings:we represent analytical results,such as designing a satellite communication network and assessing reservoir operation methods,to demonstrate that our suggested thoughts may be used in DM.Aim:We studied a new testing method for the arti-ficial communication system to give proof of the future construction of satellite earth stations.We aim to identify the best one from the different testing places.We are alsofinding the best operation schemes in the reservoir.In this article,we present the concepts of Laplacian energy(LE)in Hesitancy fuzzy graphs(HFGs),the weight function of LE of HFGs,and the TOPSIS method technique is used to produce the hesitancy fuzzy weighted-average(HFWA).Also,consider practical examples to illustrate the applicability of thefinest design of satellite communication systems and also evaluation of reservoir schemes.展开更多
Last time the world faced a deadly pandemic was the H1N1 Spanish flu in 1918, which affected almost one third of the world’s population (500 million people). Since then, almost 100 years later, we are now facing anot...Last time the world faced a deadly pandemic was the H1N1 Spanish flu in 1918, which affected almost one third of the world’s population (500 million people). Since then, almost 100 years later, we are now facing another pandemic of the SARS-CoV2 virus (Covid-19), which is still endemic to this day. As technology evolved during those 100 years, an effective vaccine for Covid-19 was produced within only a year, a huge feat. But, unfortunately, due to its fast development, another force would arise limiting the impact of the vaccine: Vacccine hesitancy and anti-vaxxers, which John Hopkins and the World Health Organization call the biggest current threat to global health. From politics to social media, it is clear that there has been a rapid spread of misinformation, resulting in hesitancy, especially from sociopolitically motivated people popularly referred to as antivaccers. However, a second group of vaccine-hesitant people have also emerged, who are uneducated and remain undecided about vaccination mostly due to safety concerns. They come under the massive influence of anti-vaxxers and anti-vaccine propaganda through social media and politicians, which often make bold claims and huge headlines. To combat vaccine hesitancy, it is crucial that we debunk these conspiracy theories and misinformation that so many believe in, with factual, data-based information. Actively spreading correct information about the vaccines, such as disclosing the rigorous developmental processes and validation of safety data by the FDA, assurance for unlikeliness of getting a lethal side effect along with tremendous health benefits, will encourage people to safe vaccination against Covid-19 and other potentially infectious diseases in future. This article discusses the role of anti-vaxxers and vaccine hesitancy groups, electronic social media, and politics in vaccine hesitancy among people. It describes the strategies to combat the roadblocks in the vaccination programs and health benefits, offered by recent advances in scientific and technological developments.展开更多
Background: Introduction of inactivated polio vaccine is imminent and may encounter the challenges that face new vaccines especially vaccine hesitancy. The study evaluated factors that may contribute to hesitancy towa...Background: Introduction of inactivated polio vaccine is imminent and may encounter the challenges that face new vaccines especially vaccine hesitancy. The study evaluated factors that may contribute to hesitancy towards IPV. Methods: Questionnaire adapted from the model developed by the Strategic Advisory Group of Experts Working Group (SAGE WG) was used to assess the factors among 408 parents. The evaluation was under the 3 Cs: Confidence, Complacency and Convenience. Questions were scored on Likert 4-unit-scale system. The data were analyzed using SPSS and, multivariate analysis was used to further test individual significant variables. Results: Overall, Complacency (2.29) and Convenience (2.11) domains were more pro-vaccine hesitant, than Confidence (1.83) domain. However, none was significantly associated with likelihood of a parent’s hesitancy towards IPV vaccination. But certain individual questions: competence of vaccinators (p = 0.04), confidence that their child will not to be infected with poliomyelitis even when not vaccinated (p = 0.03) and, willingness to vaccinate with IPV when OPV is still in use (p = 0.01) were significantly associated with vaccine hesitancy. Conclusions: None of the factors can individually influence acceptance of IPV. However, competence of vaccinators, parental belief and availability of close alternative influenced parental decision to vaccinate.展开更多
Introduction: Vaccination provides health and economic benefits to the individual and to society. In Saudi Arabia, public support for immunisation programmes is generally high and well received. However, the benefits ...Introduction: Vaccination provides health and economic benefits to the individual and to society. In Saudi Arabia, public support for immunisation programmes is generally high and well received. However, the benefits of vaccines are often not fully known or appreciated. When public discussion on vaccine safety, quality or efficacy occurs, very often misinformation creeps into the debate through the internet and other media sources, significantly weakening immunisation programmes. Vaccine hesitancy is a concept frequently used in the discourse around vaccine acceptance. This study reflects on the factors associated with vaccine hesitancy, through a study focusing on knowledge, attitudes and beliefs among parents of young children. Methods: A cross-sectional study was carried out in seven primary schools in Makkah city, Saud Arabia. Data were collected in 2017 through a computer based-survey administered to 100 parents with children aged between 2 months and 17 years of age. Questionnaire responses were analysed using Minitab. Results: Many parents (with a total of 292 children) agreed on the importance of vaccinations, to protect their children’s health and to prevent the spread of diseases in the community. Most parents (68.7%, P Discussion and Conclusions: Vaccine hesitancy is a common problem in Makkah, Saudi Arabia. Further research will be needed to better understand when, how and why these beliefs are formed.展开更多
The government of Pakistan started vaccination campaign for the frontline healthcare pro-viders, as they are more likely to be exposed to COVID-19 patients. In the next step, it ex-tended the free vaccination campaign...The government of Pakistan started vaccination campaign for the frontline healthcare pro-viders, as they are more likely to be exposed to COVID-19 patients. In the next step, it ex-tended the free vaccination campaign to include people above 60 and 50 years of age re-spectively. The drive is now open to all citizens >18 years of age. There is a significant re-luctance to get vaccinated even though the government has provided it free of cost. The project uses self-reporting method to assess reasons of vaccine hesitancy among Pakistanis and possible solutions to overcome this problem. Concern for serious side effects was the most common issue 154 (48.42%) reported among all groups of people, including the healthcare workers. The major sources of COVID-19 related information were television 117 (36.8%) and healthcare professionals 105 (33%). The participants reported that they can be convinced to get vaccinated if more published data related to vaccine efficacy and safety is available 118 (37.1%), they observe no side effect among vaccine recipients 90 (28.3%) or higher government officials get the same vaccine 39 (12.3%). Vigorous analysis and publication of data generated is paramount to increase the percentage of people being vaccinated. The healthcare professionals should share evidence-based knowledge related to vaccine efficacy and safety through television and social media to increase acceptance rates and hence, decrease mortality and morbidity from COVID-19 in Pakistan.展开更多
IntroductionThe severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has taken a toll on humans,and the development of effective vaccines has been a promising tool to end the pandemic.However,for a vacc...IntroductionThe severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has taken a toll on humans,and the development of effective vaccines has been a promising tool to end the pandemic.However,for a vaccination program to be successful,a considerable proportion of the community must be vaccinated.Hence,public acceptance of coronavirus disease 2019(COVID-19)vaccines has become the key to controlling the pandemic.Recent studies have shown vaccine hesitancy increasing over time.This systematic review aims to evaluate the COVID-19 vaccine hesitancy rate and related factors in different communities.MethodA comprehensive search was performed in MEDLINE(via PubMed),Scopus,and Web of Science from January 1,2019 to January 31,2022.All relevant descriptive and observational studies(cross-sectional and longitudinal)on vaccine hesitancy and acceptance were included in this systematic review.In the meta-analysis,odds ratio(OR)was used to assess the effects of population characteristics on vaccine hesitancy,and event rate(acceptance rate)was the effect measure for overall acceptance.Publication bias was assessed using the funnel plot,Egger's test,and trim-and-fill methods.ResultA total of 135 out of 6,417 studies were included after screening.A meta-analysis of 114 studies,including 849,911 participants,showed an overall acceptance rate of 63.1%.In addition,men,married individuals,educated people,those with a history of flu vaccination,those with higher income levels,those with comorbidities,and people living in urban areas were less hesitant.ConclusionIncreasing public awareness of the importance of COVID-19 vaccines in overcoming the pandemic is crucial.Being men,living in an urban region,being married or educated,having a history of influenza vaccination,having a higher level of income status,and having a history of comorbidities are associated with higher COVID-19 vaccine acceptance.展开更多
Introduction:Tetanus remains a significant public health concern in China,with a notable proportion of injured patients declining tetanus vaccination.This study aims to investigate the prevalence and determinants of t...Introduction:Tetanus remains a significant public health concern in China,with a notable proportion of injured patients declining tetanus vaccination.This study aims to investigate the prevalence and determinants of tetanus vaccine hesitancy and identify effective strategies to address this critical public health challenge.Methods:We calculated tetanus vaccine hesitancy rates among trauma patients presenting at eight hospitals across China from April 1 to June 30,2024.A comprehensive questionnaire survey was conducted from June 3 to June 27,2024,targeting patients aged 11 years and older who had open wounds requiring tetanus immunization but refused vaccination.The survey assessed participants’sociodemographic characteristics,knowledge,attitudes,and practices regarding tetanus and tetanus vaccines.Statistical analyses included Pearson’s Chi-squared tests,multiple response analyses,and goodness of fit tests.Results:Among 8,993 trauma patients requiring tetanus vaccination,26.78%declined immunization.Analysis of 503 consecutively collected questionnaires revealed low overall awareness of tetanus and tetanus vaccines,with only 20.1%of respondents demonstrating comprehensive knowledge of tetanusrelated questions.The predominant reason for vaccine hesitancy(34.5%)was the perception that post-injury tetanus risk was minimal.Across all age groups,medical institutions and healthcare professionals were consistently identified as the most effective sources for tetanus prevention information.Conclusion:This study demonstrates that enhancing public awareness about tetanus and its vaccines while addressing complacency are fundamental to reducing vaccine hesitancy.Targeted educational interventions delivered by healthcare institutions and professionals can significantly improve public knowledge and acceptance of tetanus vaccination.展开更多
Background Maternal influenza vaccine hesitancy plays a vital role in the low rates of vaccination.However,instruments to appropriately assess perinatal influenza vaccine hesitancy are unavailable.This study aimed to ...Background Maternal influenza vaccine hesitancy plays a vital role in the low rates of vaccination.However,instruments to appropriately assess perinatal influenza vaccine hesitancy are unavailable.This study aimed to develop the Maternal Influenza Vaccine Hesitancy Scale based on the 5C vaccination hesitancy scale,containing the subscales of confidence,complacency,constraints,calculative,and collective responsibility,and to provide a preliminary overview of the current hesitancy on maternal influenza vaccination in China.Methods A cross-sectional survey,from January to March 2024,was carried out among 2035 pregnant and postpartum women from nine provincial-level administrative divisions representing eastern,central,western,and northeastern areas of China.Reliability was evaluated by internal consistency reliability and split-half reliability,and a Cronbach’s alpha coefficient>0.7 was considered acceptable.Construct validity was assessed using confirmatory factor analysis(CFA),with good model fit defined as root mean square error of approximation(RMSEA)<0.100,normed fit index(NFI)>0.9,comparative fit index(CFI)>0.9,and Tucker-Lewis index(TLI)>0.9.Results Confirmatory factor analysis results supported the five-factor structure of the scale(RMESA=0.098,CFI=0.921,TLI=0.903,NFI=0.918).The Cronbach’s alpha coefficients for the scale as well as the subscales ranged from 0.802 to 0.958.Among five subscales,collective responsibility(2.73±0.63)scored highest,while complacency(2.16±0.69)and constraints(2.17±0.69)were the lowest.Conclusions The Maternal Influenza Vaccine Hesitancy Scale developed in this study is a reliable and valid instrument to measure the influenza vaccine hesitancy of pregnant and postpartum women.It is recommended that interventions including health education and improving the access to the vaccination service be carried out to reduce the maternal influenza vaccination hesitancy.展开更多
After the discovery and approval of coronavirus disease 2019(COVID-19)vaccines,the World Health Organization(WHO)set global vaccination coverage targets to achieve herd immunity,aiming to vaccinate at least 70% of the...After the discovery and approval of coronavirus disease 2019(COVID-19)vaccines,the World Health Organization(WHO)set global vaccination coverage targets to achieve herd immunity,aiming to vaccinate at least 70% of the global population[1].However,the availability of COVID-19 vaccination services in Africa was delayed compared to other regions,leading to lower uptake during the initial stages of the pandemic,hence leaving a considerable portion of the population unvaccinated[2].展开更多
The adoption of a stakeholder approach to public engagement within the public sector has been extensive. However, there remain critical gaps in the understanding of stakeholder participation arising from hidden dispar...The adoption of a stakeholder approach to public engagement within the public sector has been extensive. However, there remain critical gaps in the understanding of stakeholder participation arising from hidden disparities that contribute to unequal access to communication channels, information, and hence ultimately knowledge and decision making. The term “epistemic injustice” has been used to describe such inequality of access and consequently, the outcome that ensues. Epistemic injustice is much overlooked in stakeholder theory. This article shows how epistemic injustice can act as a barrier to effective stakeholder engagement and hence to successful public policy formulation and implementation. We use the case of vaccine hesitancy among Scotland's African, Caribbean, and Black(ACB) communities to illustrate this problem of unequal participation. The study drew on primary data involving 85 participants and secondary data sources from extant literature and explored salient factors shaping barriers to vaccine uptake during the recent pandemic. The findings demonstrate how the failure to grasp epistemic injustice undermines the effectiveness of the stakeholder approach, even with the most wellintentioned efforts. We argue that epistemic injustice is a critical barrier to effective stakeholder approaches.展开更多
This article uses postcolonial theory to examine optimal risk communication practices of new risks and scientifi c information to non-indigenous communities.The article calls on risk communication scholars and health ...This article uses postcolonial theory to examine optimal risk communication practices of new risks and scientifi c information to non-indigenous communities.The article calls on risk communication scholars and health practitioners to embrace postcolonial theory as it provides a critical and refl ective framework to examine ontological beliefs and methodological and structural aspects in the communication of public health messages.The article draws on insight from three studies on COVID-19 vaccine hesitancy within Scotland's African,Caribbean,and Black communities between March 2021 and April 2022.The article off ers new insight into why some communities hesitate to respond to public health messages such as vaccine uptake advice.Therefore,risk communication scholars should use the postcolonial lens to examine their assumptions,thinking,and perspectives on communicating new science and risk information in emergencies.Postcolonial theory enables risk communication scholars to address power imbalances,representation,and inclusion challenges in public health communication and trust-building eff orts.展开更多
文摘Objective:To examine the change in COVID-19 booster vaccine hesitancy according to descriptive characteristics,characteristics related to COVID-19,health literacy(HL)skills related to booster dose.Methods:The inclusion criterion was the completion of the primary scheme as two doses of COVID-19 vaccine.The study was conducted in January 2022 by applying face-to-face interview technique.Questions regarding HL were used to question the ability of individuals to access,understand,interpret and use information regarding the COVID-19 booster dose in their decisions.Results:A total of 1210 people were included in this study with an mean age of(41.3±16.6)years,and 51.4%were women.In multivariate analysis,hesitation increased in the"moderately concerned"(aOR 2.65,95%CI 1.09-6.45),"slightly concerned"(aOR 3.01,95%CI 1.26-7.19),"not concerned at all”(aOR 5.69,95%CI 2.27-14.28)groups compared to the group“extremely concerned”about COVID-19 transmission.Those with Sinovac-CoronaVac as their most recent vaccine had increased hesitation compared to those with Pfizer-BioNTech(aOR 3.68,95%CI 2.05-6.61).The effect of HL skills including“accessing”,“understanding”,and“appraising”information on hesitation was not statistically significant(P>0.05).HL skill of“applying”was assessed with ability of information to help decision making.Whether the information is helpful for decision-making,the risk of hesitancy increased for those who stated that it"sometimes helps"(aOR 2.55;95%CI 1.31-4.99)and"never helps"(aOR 11.62;95%CI 3.03-44.58)compared to those who stated that it"always helps".Conclusions:The increased propability of hesitation in those less concerned about COVID-19 transmission shows the importance of appropriately guiding individuals'concern levels with a health communication strategy based on risk communication.The fact that the only HL skill with a significant effect in the multivariate model was“applying”,shows the critical role of this skill in influencing behavioral changes.
基金supported by The National Key Research and Development Program(Grant No.2024YFA0917200)University of Science and Technology of China(Grant No.2024YCHX07)Chinese Academy of Sciences(Grant No.CX2110240028).
文摘Background:Vaccine hesitancy remains a pressing global challenge,impacting the acceptance and distribution of both long-established and newly developed vaccines.This paper investigates the multifaceted nature of vaccine hesitancy,focusing on the development of the measles vaccine as a historical case study,while drawing comparisons to the coronavirus disease 2019(COVID-19)pandemic.Methods:The study employs a historical and comparative approach to analyze vaccine hesitancy.It examines how technological advances,public policy,and communication strategies have influenced vaccine acceptance.Key lessons from the development of the measles vaccine are compared with challenges encountered during the rapid development and deployment of COVID-19 vaccines.Results:Both historical and contemporary examples reveal commonalities and differences in addressing vaccine hesitancy.While the measles vaccine demonstrated the importance of long-term safety evaluations and public trust-building,the COVID-19 vaccine highlighted the challenges of rapid development timelines and combating misinformation in a digital age.The findings underscore the necessity of transparent communication,equitable access,and proactive engagement in overcoming hesitancy.Conclusion:Understanding the historical and contemporary dynamics of vaccine hesitancy is crucial for promoting public trust and equitable vaccination in an evolving global health landscape.Effective strategies,combining historical lessons with modern innovations,can address public concerns and enhance vaccine acceptance.
基金District of Medical and Health Research Project(2023JD212)Shenzhen Bao’an District of Traditional Chinese Medicine Clinical Research Project(2023ZYYLCZX-12)+2 种基金Shenzhen“Medical and Health Three Projects”Project Grant(SZZYSM 202106003)Weifang Health Committee Scientific Research Project(wfwsjk-2023-170)Shenzhen Pingshan District of Health System Research Project(2024334).
文摘Bacckground:Based on the 3C model,this study explores the current situation of HPV vaccine hesitancy among women of childbearing age and the factors influencing vaccine hesitancy.Methods:Based on the free cervical cancer screening project in Baoan District,this study designed a questionnaire under the framework of vaccine hesitation 3C theory and carried out a self-filling electronic questionnaire survey among women of childbearing age.Results:The rate of HPV vaccination awareness among women of childbearing age in Bao’an District was 93.25%.HPV vaccine acceptance reached 71.55%,and 24.59%of the survey respondents experienced HPV vaccine hesitation,a high percentage of whom were hesitant.The influencing factors of HPV vaccine hesitation among women of childbearing age were perceived necessity of HPV vaccination(0.482),no one around them receiving the HPV vaccine(0.411),perception of the price of the vaccine(0.354),degree of trust in the safety of the vaccine(0.223),and degree of concern about the HPV vaccine(0.153).Conclusion:The 3C model can be used for the study of HPV vaccine hesitancy.Strengthening the publicity of HPV vaccination and improving women’s knowledge of the HPV vaccine can reduce their hesitation toward HPV vaccination.
文摘Introduction: The coronavirus disease 2019 (COVID-19) is an infectious disease of the respiratory tract caused by SARS-CoV-2. Since its emergence, there have been increased rates of transmission and spread, morbidity and mortality which led to the development of COVID-19 vaccines to address the pandemic. This study assessed acceptance, knowledge, attitude, and perceived risks regarding COVID-19 vaccines among pregnant women attending antenatal care at two First-Level Hospitals in Lusaka, Zambia. Materials and Methods: This was a cross-sectional study that was conducted among 241 pregnant women using a questionnaire from August 2023 to October 2023 in two First-Level Hospitals in Lusaka district, Zambia. The collected data were analyzed using IBM Statistical Package for Social Sciences (SPSS) version 22.0. Statistical analysis was performed using a Chi-square test. The statistical significance was set at a 95% confidence level. Results: Of the 241 participants, 107 (42.7%) were aged between 24 and 34 years. Overall, 64.3% accepted the COVID-19 vaccines, of which 122 (50.6%) were already vaccinated. Further, 203 (84.6%) of the pregnant women had good knowledge, and 199 (82.6%) had positive attitudes towards COVID-19 vaccines. However, 58.5% thought COVID-19 vaccines were not safe and could cause infertility. Alongside this, 70.1% thought that COVID-19 vaccines were harmful during pregnancy. Having good knowledge of COVID-19 vaccines was associated with age (p = 0.049), education status (p = 0.001), and employment status (p = 0.001). Having a positive attitude towards COVID-19 vaccines was associated with education status (p = 0.001) and employment status (p = 0.001). Conclusion: This study found that most pregnant women had good knowledge, and positive attitudes, and the majority accepted the COVID-19 vaccine. Encouragingly, most of the pregnant women who accepted the COVID-19 vaccines were already vaccinated. Most pregnant women thought that COVID-19 vaccines had side effects, were not safe, and could be harmful during pregnancy. Consequently, this could have contributed to the hesitancy to receive a vaccine among some participants. The findings of this study demonstrate the need to provide pregnant women with continuous educational programs on the benefits of vaccinations for themselves and their children.
文摘Perceptions of vaccine safety, importance and effectiveness are at the core of vaccine hesitancy around the world, and Africa has had its own share of vaccine revolts. This study uses the 2018 Wellcome Global Monitor on public perceptions of vaccines in 40 African countries to examine the predictors of vaccine hesitancy.It examines levels of hesitancy from a language perspective, comparing French speakers with others, mostly English speakers. Results show that French speakers were significantly more hesitant about importance and safety, while English speakers and others were more hesitant about effectiveness. This reflects the continuing influence of colonial ties on African countries. Respondents with high levels of trust in social actors(such as national government, journalists, people neighborhood, doctors and nurses) were also more hesitant about the safety and effectiveness of vaccines, indicating the importance of non-scientists in influencing vaccine hesitancy. Those with high levels of education were more likely to be hesitant about vaccines in general, indicating that having more education may have an opposite effect. Perception of science as progress was significant for all three hesitancy types, indicating that Africans with more progressive attitudes were less likely to worry about the importance, safety and effectiveness of vaccines. At the country level, there was no overarching predictor, indicating the strong role of local social and cultural factors.These findings improve our understanding of the drivers of vaccine hesitancy in Africa and provide valuable input for future vaccine policy and health-awareness campaigns.
基金This research work supported and funded was provided by Vellore Institute of Technology.
文摘The hesitancy fuzzy graphs(HFGs),an extension of fuzzy graphs,are useful tools for dealing with ambiguity and uncertainty in issues involving decision-making(DM).This research implements a correlation coefficient measure(CCM)to assess the strength of the association between HFGs in this article since CCMs have a high capacity to process and interpret data.The CCM that is proposed between the HFGs has better qualities than the existing ones.It lowers restrictions on the hesitant fuzzy elements’length and may be used to establish whether the HFGs are connected negatively or favorably.Additionally,a CCMbased attribute DM approach is built into a hesitant fuzzy environment.This article suggests the use of weighted correlation coefficient measures(WCCMs)using the CCM concept to quantify the correlation between two HFGs.The decisionmaking problems of hesitancy fuzzy preference relations(HFPRs)are considered.This research proposes a new technique for assessing the relative weights of experts based on the uncertainty of HFPRs and the correlation coefficient degree of each HFPR.This paper determines the ranking order of all alternatives and the best one by using the CCMs between each option and the ideal choice.In the meantime,the appropriate example is given to demonstrate the viability of the new strategies.
文摘BACKGROUND The coronavirus disease 2019(COVID-19)pandemic posed new challenges in patient care worldwide.Vaccinations,which have proven efficacious in lowering the COVID-19 hospital burden,are still avoided by large populations.We,therefore,hypothesized that hospital care teams would have worse perceptions regarding the characteristics and care of patients with vaccine hesitancy.AIM To evaluate whether patient vaccine hesitancy affected the hospital care team(HCT)perceptions.METHODS We performed a prospective clinical study using structured questionnaires.We approached physicians and nurses with previous experience caring for COVID-19patients from 11 medical centers across Israel during the fourth COVID-19 surge(September and October 2021).The participants completed a questionnaire with the following parts:(1)Sociodemographic characteristics;(2)Assessment of anger(STAXI instrument)and chronic workplace stress(Shirom-Melamed burnout measure);and(3)Three tools to assess the effect of patient vaccine hesitancy on the HCT perceptions(the difficult doctor-patient relation questionnaire,the medical staff perception of patient’s responsibility questionnaire and the characterological derogation questionnaire).Results were evaluated according to each part of the questionnaire and the questionnaire as a whole.Associations between HCT perceptions and their baseline characteristics,anger or chronic workplace stress were assessed.RESULTS The HCT experienced their relationship with unvaccinated patients as more difficult(P<0.001,Cohen’s d=0.85),perceived unvaccinated patients as responsible for their medical condition(P<0.001,d=1.39)and perceived vaccinated patients as having a higher character value(P<0.001,d=1.03).Unvaccinated patients were considered selfish(P<0.001),less mature(P<0.001)and less satisfying to care for(P<0.001).The relationship with unvaccinated patients was more difficult among HCT with higher burnout(r=0.37,n=66,P=0.002).No correlations with baseline characteristics were found.All three study tools showed high internal consistency(αbetween 0.72 and 0.845).CONCLUSION Our results should raise awareness of the possible effects of vaccine hesitancy on HCT perceptions regarding unvaccinated patients.In order to minimize the potential negative impact on patient care,designated departments should promote specific patient-centered preparations.Further investigations should assess whether vaccine hesitancy directly affects patient quality of care.
文摘Objective:To examine the pattern of COVID-19 infection and vaccination,and to explore pregnant women’s willingness and reluctance to accept a booster dose of the COVID-19 vaccine.Methods:This was a cross-sectional,descriptive study with a convenient sample size using a structured questionnaire among pregnant women attending the gynecology and obstetrics department at Acıbadem Mehmet Ali Aydinlar Hospital,Istanbul,Türkiye.The Health Belief Model scale was used to assess the intention and reluctance to accept a booster dose of the COVID-19 vaccine.Results:A total of 145 participants,with a mean age of(33.5±4.8)years,and a gestational age of(30.9±7.3)weeks,were enrolled in this study.88.8%Received full doses of the Pfizer-BioNTech vaccination.47.8%Participants suffered from vaccine adverse effects.Health Belief Model demonstrated a significant finding of perceived susceptibility(P<0.001),perceived severity of COVID-19 complications(P<0.001),and perceived benefits regarding a booster COVID-19 vaccination(P<0.001).Conclusions:Most pregnant women who received the COVID-19 immunization express a significant intention to receive a booster dose,regardless of the adverse effects experienced from the previous doses.However,a small percentage of the study sample express hesitancy about receiving the booster dose.
文摘Diabetes mellitus is one of the most common comorbid conditions encountered in patients with severe acute respiratory syndrome coronavirus 2 infection accompanied by significantly increased mortality,prolonged hospital stay,and requirement of invasive mechanical ventilation.This review aims to present the effectiveness and safety profile of available coronavirus disease 2019(COVID-19)vaccines in people with diabetes as a potential cause of hesitancy for vaccination.Data from published research proves a robust immune response following immunization for COVID-19 in diabetic patients with substantial production of virus-neutralizing antibodies;however,the observed immune response was unequivocally weaker than that in individuals without diabetes.This observation was further enhanced by the findings that worse glycemic control was associated with more suppressed antibody production.In contrast,individuals with optimal glycemic control performed similarly to healthy controls.In addition to the need for strict glucose monitoring and adequate diabetes treatment,those findings reinforce the concept of diabetes-induced secondary immune deficiency and necessitate the application of booster doses to diabetic patients with priority.Nevertheless,after vaccination,reported adverse events were not different from those in the general population.No increase in severe adverse events was documented.While single case reports detected transient increases in blood glucose post-vaccination,more extensive trials could not replicate such a relationship.
文摘Decision-making(DM)is a process in which several persons concur-rently engage,examine the problems,evaluate potential alternatives,and select an appropriate option to the problem.Technique for determining order preference by similarity to the ideal solution(TOPSIS)is an established DM process.The objective of this report happens to broaden the approach of TOPSIS to solve the DM issues designed with Hesitancy fuzzy data,in which evaluation evidence given by the experts on possible solutions is presents as Hesitancy fuzzy decision matrices,each of which is defined by Hesitancy fuzzy numbers.Findings:we represent analytical results,such as designing a satellite communication network and assessing reservoir operation methods,to demonstrate that our suggested thoughts may be used in DM.Aim:We studied a new testing method for the arti-ficial communication system to give proof of the future construction of satellite earth stations.We aim to identify the best one from the different testing places.We are alsofinding the best operation schemes in the reservoir.In this article,we present the concepts of Laplacian energy(LE)in Hesitancy fuzzy graphs(HFGs),the weight function of LE of HFGs,and the TOPSIS method technique is used to produce the hesitancy fuzzy weighted-average(HFWA).Also,consider practical examples to illustrate the applicability of thefinest design of satellite communication systems and also evaluation of reservoir schemes.
文摘Last time the world faced a deadly pandemic was the H1N1 Spanish flu in 1918, which affected almost one third of the world’s population (500 million people). Since then, almost 100 years later, we are now facing another pandemic of the SARS-CoV2 virus (Covid-19), which is still endemic to this day. As technology evolved during those 100 years, an effective vaccine for Covid-19 was produced within only a year, a huge feat. But, unfortunately, due to its fast development, another force would arise limiting the impact of the vaccine: Vacccine hesitancy and anti-vaxxers, which John Hopkins and the World Health Organization call the biggest current threat to global health. From politics to social media, it is clear that there has been a rapid spread of misinformation, resulting in hesitancy, especially from sociopolitically motivated people popularly referred to as antivaccers. However, a second group of vaccine-hesitant people have also emerged, who are uneducated and remain undecided about vaccination mostly due to safety concerns. They come under the massive influence of anti-vaxxers and anti-vaccine propaganda through social media and politicians, which often make bold claims and huge headlines. To combat vaccine hesitancy, it is crucial that we debunk these conspiracy theories and misinformation that so many believe in, with factual, data-based information. Actively spreading correct information about the vaccines, such as disclosing the rigorous developmental processes and validation of safety data by the FDA, assurance for unlikeliness of getting a lethal side effect along with tremendous health benefits, will encourage people to safe vaccination against Covid-19 and other potentially infectious diseases in future. This article discusses the role of anti-vaxxers and vaccine hesitancy groups, electronic social media, and politics in vaccine hesitancy among people. It describes the strategies to combat the roadblocks in the vaccination programs and health benefits, offered by recent advances in scientific and technological developments.
文摘Background: Introduction of inactivated polio vaccine is imminent and may encounter the challenges that face new vaccines especially vaccine hesitancy. The study evaluated factors that may contribute to hesitancy towards IPV. Methods: Questionnaire adapted from the model developed by the Strategic Advisory Group of Experts Working Group (SAGE WG) was used to assess the factors among 408 parents. The evaluation was under the 3 Cs: Confidence, Complacency and Convenience. Questions were scored on Likert 4-unit-scale system. The data were analyzed using SPSS and, multivariate analysis was used to further test individual significant variables. Results: Overall, Complacency (2.29) and Convenience (2.11) domains were more pro-vaccine hesitant, than Confidence (1.83) domain. However, none was significantly associated with likelihood of a parent’s hesitancy towards IPV vaccination. But certain individual questions: competence of vaccinators (p = 0.04), confidence that their child will not to be infected with poliomyelitis even when not vaccinated (p = 0.03) and, willingness to vaccinate with IPV when OPV is still in use (p = 0.01) were significantly associated with vaccine hesitancy. Conclusions: None of the factors can individually influence acceptance of IPV. However, competence of vaccinators, parental belief and availability of close alternative influenced parental decision to vaccinate.
文摘Introduction: Vaccination provides health and economic benefits to the individual and to society. In Saudi Arabia, public support for immunisation programmes is generally high and well received. However, the benefits of vaccines are often not fully known or appreciated. When public discussion on vaccine safety, quality or efficacy occurs, very often misinformation creeps into the debate through the internet and other media sources, significantly weakening immunisation programmes. Vaccine hesitancy is a concept frequently used in the discourse around vaccine acceptance. This study reflects on the factors associated with vaccine hesitancy, through a study focusing on knowledge, attitudes and beliefs among parents of young children. Methods: A cross-sectional study was carried out in seven primary schools in Makkah city, Saud Arabia. Data were collected in 2017 through a computer based-survey administered to 100 parents with children aged between 2 months and 17 years of age. Questionnaire responses were analysed using Minitab. Results: Many parents (with a total of 292 children) agreed on the importance of vaccinations, to protect their children’s health and to prevent the spread of diseases in the community. Most parents (68.7%, P Discussion and Conclusions: Vaccine hesitancy is a common problem in Makkah, Saudi Arabia. Further research will be needed to better understand when, how and why these beliefs are formed.
文摘The government of Pakistan started vaccination campaign for the frontline healthcare pro-viders, as they are more likely to be exposed to COVID-19 patients. In the next step, it ex-tended the free vaccination campaign to include people above 60 and 50 years of age re-spectively. The drive is now open to all citizens >18 years of age. There is a significant re-luctance to get vaccinated even though the government has provided it free of cost. The project uses self-reporting method to assess reasons of vaccine hesitancy among Pakistanis and possible solutions to overcome this problem. Concern for serious side effects was the most common issue 154 (48.42%) reported among all groups of people, including the healthcare workers. The major sources of COVID-19 related information were television 117 (36.8%) and healthcare professionals 105 (33%). The participants reported that they can be convinced to get vaccinated if more published data related to vaccine efficacy and safety is available 118 (37.1%), they observe no side effect among vaccine recipients 90 (28.3%) or higher government officials get the same vaccine 39 (12.3%). Vigorous analysis and publication of data generated is paramount to increase the percentage of people being vaccinated. The healthcare professionals should share evidence-based knowledge related to vaccine efficacy and safety through television and social media to increase acceptance rates and hence, decrease mortality and morbidity from COVID-19 in Pakistan.
文摘IntroductionThe severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has taken a toll on humans,and the development of effective vaccines has been a promising tool to end the pandemic.However,for a vaccination program to be successful,a considerable proportion of the community must be vaccinated.Hence,public acceptance of coronavirus disease 2019(COVID-19)vaccines has become the key to controlling the pandemic.Recent studies have shown vaccine hesitancy increasing over time.This systematic review aims to evaluate the COVID-19 vaccine hesitancy rate and related factors in different communities.MethodA comprehensive search was performed in MEDLINE(via PubMed),Scopus,and Web of Science from January 1,2019 to January 31,2022.All relevant descriptive and observational studies(cross-sectional and longitudinal)on vaccine hesitancy and acceptance were included in this systematic review.In the meta-analysis,odds ratio(OR)was used to assess the effects of population characteristics on vaccine hesitancy,and event rate(acceptance rate)was the effect measure for overall acceptance.Publication bias was assessed using the funnel plot,Egger's test,and trim-and-fill methods.ResultA total of 135 out of 6,417 studies were included after screening.A meta-analysis of 114 studies,including 849,911 participants,showed an overall acceptance rate of 63.1%.In addition,men,married individuals,educated people,those with a history of flu vaccination,those with higher income levels,those with comorbidities,and people living in urban areas were less hesitant.ConclusionIncreasing public awareness of the importance of COVID-19 vaccines in overcoming the pandemic is crucial.Being men,living in an urban region,being married or educated,having a history of influenza vaccination,having a higher level of income status,and having a history of comorbidities are associated with higher COVID-19 vaccine acceptance.
基金Supported by the National High Level Hospital Clinical Research Funding(Interdepartmental Research Project of Peking University First Hospital:2024IR10).
文摘Introduction:Tetanus remains a significant public health concern in China,with a notable proportion of injured patients declining tetanus vaccination.This study aims to investigate the prevalence and determinants of tetanus vaccine hesitancy and identify effective strategies to address this critical public health challenge.Methods:We calculated tetanus vaccine hesitancy rates among trauma patients presenting at eight hospitals across China from April 1 to June 30,2024.A comprehensive questionnaire survey was conducted from June 3 to June 27,2024,targeting patients aged 11 years and older who had open wounds requiring tetanus immunization but refused vaccination.The survey assessed participants’sociodemographic characteristics,knowledge,attitudes,and practices regarding tetanus and tetanus vaccines.Statistical analyses included Pearson’s Chi-squared tests,multiple response analyses,and goodness of fit tests.Results:Among 8,993 trauma patients requiring tetanus vaccination,26.78%declined immunization.Analysis of 503 consecutively collected questionnaires revealed low overall awareness of tetanus and tetanus vaccines,with only 20.1%of respondents demonstrating comprehensive knowledge of tetanusrelated questions.The predominant reason for vaccine hesitancy(34.5%)was the perception that post-injury tetanus risk was minimal.Across all age groups,medical institutions and healthcare professionals were consistently identified as the most effective sources for tetanus prevention information.Conclusion:This study demonstrates that enhancing public awareness about tetanus and its vaccines while addressing complacency are fundamental to reducing vaccine hesitancy.Targeted educational interventions delivered by healthcare institutions and professionals can significantly improve public knowledge and acceptance of tetanus vaccination.
基金This research was funded by Bill&Melinda Gates Foundation-supported project"Laboratory for Innovations in Vaccine and Immunization Service Delivery":INV-034554Key Discipline Construction Project of the Sixth Round of the 3 Years Action Plan to Strengthen Public Health Systems in Shanghai:GWVI-11.1-32.
文摘Background Maternal influenza vaccine hesitancy plays a vital role in the low rates of vaccination.However,instruments to appropriately assess perinatal influenza vaccine hesitancy are unavailable.This study aimed to develop the Maternal Influenza Vaccine Hesitancy Scale based on the 5C vaccination hesitancy scale,containing the subscales of confidence,complacency,constraints,calculative,and collective responsibility,and to provide a preliminary overview of the current hesitancy on maternal influenza vaccination in China.Methods A cross-sectional survey,from January to March 2024,was carried out among 2035 pregnant and postpartum women from nine provincial-level administrative divisions representing eastern,central,western,and northeastern areas of China.Reliability was evaluated by internal consistency reliability and split-half reliability,and a Cronbach’s alpha coefficient>0.7 was considered acceptable.Construct validity was assessed using confirmatory factor analysis(CFA),with good model fit defined as root mean square error of approximation(RMSEA)<0.100,normed fit index(NFI)>0.9,comparative fit index(CFI)>0.9,and Tucker-Lewis index(TLI)>0.9.Results Confirmatory factor analysis results supported the five-factor structure of the scale(RMESA=0.098,CFI=0.921,TLI=0.903,NFI=0.918).The Cronbach’s alpha coefficients for the scale as well as the subscales ranged from 0.802 to 0.958.Among five subscales,collective responsibility(2.73±0.63)scored highest,while complacency(2.16±0.69)and constraints(2.17±0.69)were the lowest.Conclusions The Maternal Influenza Vaccine Hesitancy Scale developed in this study is a reliable and valid instrument to measure the influenza vaccine hesitancy of pregnant and postpartum women.It is recommended that interventions including health education and improving the access to the vaccination service be carried out to reduce the maternal influenza vaccination hesitancy.
基金funded by the Rockefeller Foundation through Amref Health Africa(grant number AMREF/MakSPH/001 to D.M.).
文摘After the discovery and approval of coronavirus disease 2019(COVID-19)vaccines,the World Health Organization(WHO)set global vaccination coverage targets to achieve herd immunity,aiming to vaccinate at least 70% of the global population[1].However,the availability of COVID-19 vaccination services in Africa was delayed compared to other regions,leading to lower uptake during the initial stages of the pandemic,hence leaving a considerable portion of the population unvaccinated[2].
文摘The adoption of a stakeholder approach to public engagement within the public sector has been extensive. However, there remain critical gaps in the understanding of stakeholder participation arising from hidden disparities that contribute to unequal access to communication channels, information, and hence ultimately knowledge and decision making. The term “epistemic injustice” has been used to describe such inequality of access and consequently, the outcome that ensues. Epistemic injustice is much overlooked in stakeholder theory. This article shows how epistemic injustice can act as a barrier to effective stakeholder engagement and hence to successful public policy formulation and implementation. We use the case of vaccine hesitancy among Scotland's African, Caribbean, and Black(ACB) communities to illustrate this problem of unequal participation. The study drew on primary data involving 85 participants and secondary data sources from extant literature and explored salient factors shaping barriers to vaccine uptake during the recent pandemic. The findings demonstrate how the failure to grasp epistemic injustice undermines the effectiveness of the stakeholder approach, even with the most wellintentioned efforts. We argue that epistemic injustice is a critical barrier to effective stakeholder approaches.
文摘This article uses postcolonial theory to examine optimal risk communication practices of new risks and scientifi c information to non-indigenous communities.The article calls on risk communication scholars and health practitioners to embrace postcolonial theory as it provides a critical and refl ective framework to examine ontological beliefs and methodological and structural aspects in the communication of public health messages.The article draws on insight from three studies on COVID-19 vaccine hesitancy within Scotland's African,Caribbean,and Black communities between March 2021 and April 2022.The article off ers new insight into why some communities hesitate to respond to public health messages such as vaccine uptake advice.Therefore,risk communication scholars should use the postcolonial lens to examine their assumptions,thinking,and perspectives on communicating new science and risk information in emergencies.Postcolonial theory enables risk communication scholars to address power imbalances,representation,and inclusion challenges in public health communication and trust-building eff orts.
