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Effects of Surface Herbs on the Growth of Populus L.Cutting Seedling,Soil Property and Ammonia Volatilization 被引量:1
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作者 Chang Liu Chengcheng Yin +1 位作者 Jinjin Zhang Haijun Sun 《Phyton-International Journal of Experimental Botany》 2025年第3期695-707,共13页
To promote the growth of cutting seeding of poplar(Populus L.),nitrogen(N)fertilizer and surface weed managements were required.We here conducted a pot experiment to examine the effects of natural vegetation,barnyardg... To promote the growth of cutting seeding of poplar(Populus L.),nitrogen(N)fertilizer and surface weed managements were required.We here conducted a pot experiment to examine the effects of natural vegetation,barnyardgrass(Echinochloa Beauv.),and sesbania(Sesbania cannabina pers.)on the growth of poplar cutting seedlings,soil properties,and ammonia(NH3)volatilization under three N inputs(0,0.5,and 1.5 g/pot,i.e.,N0,N0.5,and N1,respectively).Results showed that N application promoted the growth of poplar cutting seedlings,including plant height,ground diameter,and biomass,compared with N0 treatment.Moreover,under N0,sesbania significantly increased the plant height by 87.1%,barnyardgrass and sesbania significantly increased the ground diameter(16.2%and 51.5%),and biomass(67.4%and 74.7%)of poplar cutting seedlings,compared with natural vegetation management.Compared to natural vegetation,soil organic matter(SOM)of barnyardgrass and sesbania covered soil significantly increased by 12.4%and 18.7%at N1,respectively.In addition,soil total N(TN)content was significantly increased by 15.8%in barnyardgrass planted at N0.The soil ammonium N(NH_(4)^(+)-N)content decreased with the planting of barnyardgrass and sesbania across all levels of N application.At N0.5,the nitrate N(NO_(3)^(−)-N)content of soil planted with barnyardgrass significantly increased compared to both the natural vegetation and the sesbania groups.Compared to the natural vegetation,the soil available phosphorus(AP)content of the barnyardgrass group significantly increasing by 78.8%at N0.5,soil available potassium(AK)content was significantly reduced by 12.5%in the sesbania group at N0 and increased by 24.1%in the barnyardgrass group at N1.We found that cumulative NH3 emissions were significantly higher in all treatment groups at the N1 level than that at the N0.5 level,while the differences among the three plants treated were not significant.The results suggest that both barnyardgrass and sesbania promote seedling growth in the short term,while also increase certain properties.Therefore,effective herb management during the seedling stage is recommended in nurseries to support seedling growth and retain soil fertility. 展开更多
关键词 herb management NH3 emission nitrogen loss nursery cultivation soil fertility
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Compatibility of cold herb CP and hot herb AZ in Huanglian Ganjiang decoction alleviates colitis mice through M1/M2 macrophage polarization balance via PDK4-mediated glucose metabolism reprogramming
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作者 Yanyang Li Chang Liu +6 位作者 Yi Wang Peiqi Chen Shihua Xu Yequn Wu Lingzhi Ren Yang Yu Lei Yang 《Chinese Journal of Natural Medicines》 2025年第10期1183-1194,共12页
Ulcerative colitis(UC)is a chronic and non-specific inflammatory bowel disease(IBD).Huanglian Ganjiang decoction(HGD),derived from ancient book Beiji Qianjin Yao Fang,has demonstrated efficacy in treating UC patients ... Ulcerative colitis(UC)is a chronic and non-specific inflammatory bowel disease(IBD).Huanglian Ganjiang decoction(HGD),derived from ancient book Beiji Qianjin Yao Fang,has demonstrated efficacy in treating UC patients traditionally.Previous research established that the compatibility of cold herb Coptidis Rhizoma+Phellodendri Chinensis Cortex(CP)and hot herb Angelicae Sinensis Radix+Zingiberis Rhizoma(AZ)in HGD synergistically improved colitis mice.This study investigated the compatibility mechanisms through which CP and AZ regulated inflammatory balance in colitis mice.The experimental colitis model was established by administering 3%dextran sulphate sodium(DSS)to mice for 7 days,followed by CP,AZ and CPAZ treatment for an additional 7 days.M1/M2 macrophage polarization levels,glucose metabolites levels and pyruvate dehydrogenase kinase 4(PDK4)expression were analyzed using flow cytometry,Western blot,immunofluorescence and targeted glucose metabolomics.The findings indicated that CP inhibited M1 macrophage polarization,decreased inflammatory metabolites associated with tricarboxylic acid(TCA)cycle,and suppressed PDK4 expression and pyruvate dehydrogenase(PDH)(Ser-293)phosphorylation level.AZ enhanced M2 macrophage polarization,increased lactate axis metabolite lactate levels,and upregulated PDK4 expression and PDH(Ser-293)phosphorylation level.TCA cycle blocker AG-221 and adeno-associated virus(AAV)-PDK4 partially negated CP’s inhibition of M1 macrophage polarization.Lactate axis antagonist oxamate and PDK4 inhibitor dichloroacetate(DCA)partially reduced AZ’s activation of M2 macrophage polarization.In conclusion,the compatibility of CP and AZ synergistically alleviated colitis in mice through M1/M2 macrophage polarization balance via PDK4-mediated glucose metabolism reprogramming.Specifically,CP reduced M1 macrophage polarization by restoration of TCA cycle via PDK4 inhibition,while AZ increased M2 macrophage polarization through activation of PDK4/lactate axis. 展开更多
关键词 Compatibility COLITIS Cold herb Hot herb Huanglian Ganjiang decoction M1/M2 macrophage polarization PDK4 Glucose metabolism reprogramming
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Combination of Astragalus−Salvia and Ophiopogon−Dendrobium herb pairs alleviates Sjögren’s Syndrome via inhibiting the JAK1/STAT3 and PI3K/AKT pathways in NOD/Ltj mice
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作者 Peng Sun Lili Zhu +6 位作者 Yang Yu Sijing Hu Mengyi Shan Xuan Zhao Xinchang Wang Qiaoyan Zhang Luping Qin 《Chinese Journal of Natural Medicines》 2025年第6期733-741,共9页
Sjögren’s syndrome(SS)is an autoimmune disease characterized primarily by oral and periocular dryness.Astragalus-Salvia(AS)and Ophiopogon-Dendrobium(OD)represent two frequently utilized herb pairs in SS treatmen... Sjögren’s syndrome(SS)is an autoimmune disease characterized primarily by oral and periocular dryness.Astragalus-Salvia(AS)and Ophiopogon-Dendrobium(OD)represent two frequently utilized herb pairs in SS treatment.While the combination of AS-OD herb pairs demonstrates clinical efficacy in alleviating SS symptoms,its underlying mechanism remains unclear.This investigation sought to assess the therapeutic effects and elucidate the potential mechanisms of AS-OD in non-obese diabetic(NOD)/Ltj mice with SS.The study utilized NOD/Ltj mice as SS models,administering AS-OD treatment for 10 weeks at doses of 113.1,226.2,and 339.3 mg·d−1·20 g−1.Results demonstrated that AS-OD improved SS symptoms,evidenced by enhanced salivary flow rate,decreased anti-SSA/Ro and anti-SSB/La antibody levels,increased swimming duration,and reduced lactate(LA)and blood urea nitrogen(BUN)levels in NOD/Ltj mice.AS-OD reduced lymphocyte infiltration,enhanced Aquaporin-5(AQP5)expression in the submandibular gland,decreased inflammatory cytokine levels in the submandibular gland,and reduced the T helper type 17/regulatory T lymphocyte(Th17/Treg)cell ratio in the spleen.Transcriptomic and proteomic analyses indicated AS-OD’s involvement in regulating phosphatidylinositol-3-kinase/protein kinase B(PI3K/AKT)and Janus kinase 3/signal transducer and activator of transcription 3(JAK1/STAT3)pathways,with inhibitory effects validated in both NOD/Ltj mice submandibular gland and A-253 cells.Furthermore,AS-OD enhanced cell viability and reduced A-253 cell apoptosis through the PI3K/AKT pathway.In A-253 cells,AS-OD reduced inflammatory cytokine levels,CXC chemokine ligand 9/10(CXCL9/10),and T-cell chemotaxis by inhibiting the JAK1/STAT3 pathway.AS-OD mitigates SS by suppressing inflammation and immune responses through the PI3K/AKT and JAK1/STAT3 pathways. 展开更多
关键词 Sjgren’s syndrome Astragalus-Salvia herb pair Ophiopogon-Dendrobium herb pair CXCL9 and CXCL10 JAK1/STAT3 PI3K/AKT
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Microecology and Geoherbalism of Traditional Chinese Medicine
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作者 Zhou Zhou Danyu Liu 《Research and Inheritance of Traditional Chinese Medicine》 2025年第2期13-48,共36页
The microecology of traditional Chinese medicine is directly or indirectly involved in the growth and development,metabolic process,and accumulation of components of herbs in various ways,which in turn has an importan... The microecology of traditional Chinese medicine is directly or indirectly involved in the growth and development,metabolic process,and accumulation of components of herbs in various ways,which in turn has an important impact on the formation and change of the authenticity of traditional Chinese medicine.It is one of the main tasks in the study of microecology of traditional Chinese medicine to reveal the relationship between the microecological structure of traditional Chinese medicine,its changing law and the efficacy of traditional Chinese medicine.The heterogeneity of soil environment due to geographic and climatic factors,and the discrete limitation due to isolation factors such as distance and host selection are the main causes of microecological geographic differentiation of Chinese medicine.The microecology of TCM has an important influence and contribution to the distinctive origin and quality attributes of local herbs,which is mainly reflected in the formation of excellent germplasm(including the ability to make the hosts more resistant to pests and diseases,drought,salt,and cold,etc.),the improvement of yield,the morphological construction of medicinal parts,the metabolic accumulation of active ingredients,the timeliness of harvest,the formation of toxicity of medicinal herbs,the enhancement of efficiency and reduction of toxicity during processing and processing,the increase of efficiency and the reduction of toxicity after introduction to cultivation,and the increase of efficiency and reduction of toxicity during processing and processing of herbs after cultivation.The study of the toxicity of medicinal herbs,the increase and decrease of toxicity during processing and preparation,the change of product effect after introduction and cultivation,and the authenticity of fungal Chinese medicine.With the rapid development of modern information technology and genomics,it is expected to become a future trend to explore the origin pathway of local chemical components based on microecology,develop metabolic synthesis reactors for Chinese medicine based on microecological quantitative-effective relationship,biomimetic cultivation of local medicinal herbs based on microecological structural restructuring of Chinese medicines,traceability of origin identification barcode based on microecology,and toxicityreducing and efficiency-enhancing technology of Chinese medicines. 展开更多
关键词 traditional Chinese medicine MICROECOLOGY Dao-di herbs origin attribute geoherbalism
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Real-world evidence for herbal medicine benefit in 9728 type 2 diabetes patients-peridonotitis risk and ambulatory care utilization
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作者 Wen-Wei Lin Chieh-Tsung Yen +4 位作者 Hanoch Livneh Hua-Lung Huang Ming-Chi Lu Wei-Jen Chen Tzung-Yi Tsai 《World Journal of Diabetes》 2025年第11期88-98,共11页
BACKGROUND Recent evidence manifests that individuals with type 2 diabetes(T2D)are increasingly affected by oral disorders.Although medicinal herbs have shown promise in managing T2D,their benefit in managing periodon... BACKGROUND Recent evidence manifests that individuals with type 2 diabetes(T2D)are increasingly affected by oral disorders.Although medicinal herbs have shown promise in managing T2D,their benefit in managing periodontitis risk and subsequent healthcare utilization remains uncertain.AIM To compare risk of periodontitis and associated ambulatory care utilization among individuals with T2D who did or did not receive add-on medicinal herbs.METHODS We included individuals aged 20-70 years with newly diagnosis of T2D and being free of periodontitis in 2000 and 2010.Periodontitis events were tracked from cohort entry until December 31,2013.The association between medicinal herb use and periodontitis risk was assessed by multivariate Cox regression,while differences in periodontitis-related ambulatory care were analyzed using Mann-Whitney U test.RESULTS After propensity score matching,9728 individuals were included in both the herbal and non-herbal groups.Those who used herbs for more than two years experienced a potently lower risk of periodontitis by 52%.Compared to herb users,the non-users substantially incurred higher frequency and cost of periodontitis-related ambulatory visits post-diagnosis,and the costs per ambulatory visit increased with time after periodontitis onset.CONCLUSION The rollout of this study not only tackled the former research gap but also provided an insight that the combination of medicinal herbs may take into account while planning holistic and individualized oral health care for T2D persons. 展开更多
关键词 Type 2 diabetes PERIODONTITIS Medicinal herbs Cohort study Interdisciplinary collaboration RISK
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Application of spectroscopic technology with machine learning in Chinese herbs from seeds to medicinal materials:The case of genus Paris
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作者 Yangna Feng Xinyan Zhu Yuanzhong Wang 《Journal of Pharmaceutical Analysis》 2025年第2期291-303,共13页
To ensure the safety and efficacy of Chinese herbs,it is of great significance to conduct rapid quality detection of Chinese herbs at every link of their supply chain.Spectroscopic technology can reflect the overall c... To ensure the safety and efficacy of Chinese herbs,it is of great significance to conduct rapid quality detection of Chinese herbs at every link of their supply chain.Spectroscopic technology can reflect the overall chemical composition and structural characteristics of Chinese herbs,with the multi-component and multitarget characteristics of Chinese herbs.This review took the genus Paris as an example,and applications of spectroscopic technology with machine learning(ML)in supply chain of the genus Paris from seeds to medicinal materials were introduced.The specific contents included the confirmation of germplasm resources,identification of growth years,cultivar,geographical origin,and original processing and processing methods.The potential application of spectroscopic technology in genus Paris was pointed out,and the prospects of combining spectroscopic technology with blockchain were proposed.The summary and prospects presented in this paper will be beneficial to the quality control of the genus Paris in all links of its supply chain,so as to rationally use the genus Paris resources and ensure the safety and efficacy of medication. 展开更多
关键词 Medicinal herbs Genus Paris Spectroscopic technology Quality detection Supply chain Machine learning
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Environmental drivers of herbaceous plant diversity in the understory community of a warm-temperate forest
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作者 Tingting Deng Qingqing Du +1 位作者 Yan Zhu Simon A.Queenborough 《Plant Diversity》 2025年第2期282-290,共9页
Herbaceous plants are an essential component of forest diversity and driver of ecosystem processes.However,because the growth forms and life-history strategies of herbaceous plants differ from those of woody plants,it... Herbaceous plants are an essential component of forest diversity and driver of ecosystem processes.However,because the growth forms and life-history strategies of herbaceous plants differ from those of woody plants,it is unclear whether the mechanisms that drive patterns plant diversity and community structure in these two plant groups are the same.In this study,we determined whether herb and woody plant communities have similar patterns and drivers of alpha-and beta-diversity.We compared species richness,distribution,and abundance of herbs to woody seedlings in a 20-ha Donglingshan warmtemperate forest(Donglingshan FDP),China.We also determined whether variation in patterns of species richness and composition are better explained by environmental or spatial variables.Herbaceous plants accounted for 72%of all species(81 herbaceous,31 woody)recorded.Alpha-and beta-diversity were higher in herbs than in woody seedlings.Although alpha-diversity of herbs and woody seedlings was not correlated across the site,the local-site contributions to beta-diversity for herbs and woody seedlings were negatively correlated.Habitat type explained slightly more variation in herb community composition than in woody seedling composition,with the highest diversity in the low-elevation slope.Environmental variables explained the variation in species richness and composition more in herbaceous plants than in woody seedlings.Our results indicate that different mechanisms drive variation in the herb and woody seedling communities,with herbs exhibiting greater environmental sensitivity and habitat dependence.These findings contribute to the better understanding of herbaceous plant diversity and composition in forest communities. 展开更多
关键词 Donglingshan FDP herbS Woody species diversity Environmental filtering Habitat associations
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Hypothalamic lipidomics reveals that AMPK-FA metabolism mediates the energy-balancing effect of the four typical“hot”herbs on hypothyroidism
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作者 Yangyang Wang Yizhou Rong +3 位作者 Liangce Chen Qi Cui Haixue Kuang Bo Yang 《Journal of Pharmaceutical Analysis》 2025年第4期876-878,共3页
That herbs with the"hot"property used to treat"cold"syndromes is a guiding principle of clinical prescription and medication in traditional Chinese medicine(TCM).However,this theory of TCM is still... That herbs with the"hot"property used to treat"cold"syndromes is a guiding principle of clinical prescription and medication in traditional Chinese medicine(TCM).However,this theory of TCM is still in the‘black box'stage,and few in-depth studies have examined the biological mechanisms underpinning the hot properties of herbs. 展开更多
关键词 biological mechanisms hypothalamic lipidomics AMPK HYPOTHYROIDISM hot herbs traditional chinese medicine tcm howeverthis traditional Chinese medicine energy balancing effect
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再论分子生药学——三十年,一个新起点
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作者 黄璐琦 郑汉 +1 位作者 袁媛 郭娟 《中国中药杂志》 北大核心 2026年第1期1-9,共9页
分子生药学自1995年概念提出至今三十年来,已从概念萌芽成长为一门理论体系完善、技术方法成熟、应用范围广泛的前沿交叉学科。该文系统回顾了该学科在理论创新、技术标准、产业应用及平台建设等方面的重要进展,包括生药分子鉴定技术标... 分子生药学自1995年概念提出至今三十年来,已从概念萌芽成长为一门理论体系完善、技术方法成熟、应用范围广泛的前沿交叉学科。该文系统回顾了该学科在理论创新、技术标准、产业应用及平台建设等方面的重要进展,包括生药分子鉴定技术标准、道地药材形成机制解析、珍稀资源保护模式建立、活性成分生物合成等领域的突破性成果;阐述了分子生药学从学科和产业存在的现象为起点,通过“问题衍生—假说预设—技术创新—理论丰富”的递进过程,形成了一个在理论与实践相互作用下不断演进的学科研究范式;分析了当前在分子鉴定精度、道地性形成机制、资源可持续利用等方面仍面临的挑战。展望未来,分子生药学将与人工智能、全景组学、量子计算、生物制造、智能育种与基因编辑等前沿技术深度融合,推动研究范式从“认识与揭示”向“预测与设计”的革命性转变,迈向精准化、系统化与工程化的新起点,为中医药现代化注入全新动力。 展开更多
关键词 分子生药学 学科演进 道地药材 人工智能 生物制造 智能育种
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基于“异病同治”理论探究川芎-天麻药对对血管性痴呆与高血压的调控作用
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作者 刘琳 齐欣 +3 位作者 杨洋 王凯 曲中原 王冬雪 《天然产物研究与开发》 北大核心 2026年第2期273-282,共10页
本研究基于“异病同治”理论,旨在探索川芎与天麻药对在治疗血管性痴呆(vascular dementia,VaD)和高血压中的双重疗效。研究采用2-VO法建立VaD模型,并使用自发性高血压大鼠(spontaneously hypertensive rats,SHR)作为高血压模型,进行了... 本研究基于“异病同治”理论,旨在探索川芎与天麻药对在治疗血管性痴呆(vascular dementia,VaD)和高血压中的双重疗效。研究采用2-VO法建立VaD模型,并使用自发性高血压大鼠(spontaneously hypertensive rats,SHR)作为高血压模型,进行了行为学、组织学及生化检测,包括Morris水迷宫实验、苏木精-伊红染色及相关炎性因子,如肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、前列腺素内过氧化合物合酶(prostaglandin-endoperoxide synthase 2,PTGS2)表达的蛋白免疫印记分析。结果显示,高剂量药对显著改善脑血流量、降低血压并缓解血管内皮损伤,同时降低了TNF-α和PTGS2等促炎因子的表达。研究表明,川芎-天麻药对在治疗这两种疾病中的有效性,证明“异病同治”策略可行。 展开更多
关键词 川芎-天麻药对 异病同治 高血压 血管性痴呆 炎症因子 血管内皮功能
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东山岛典型森林草本层β多样性及其驱动因素
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作者 王彬彬 林曼妮 +3 位作者 朱琦琦 肖自新 李培杨 邓传远 《东北林业大学学报》 北大核心 2026年第2期58-67,共10页
探究植物群落间物种组成差异,有助于深入了解植物β多样性格局及其驱动机制,提高对海岛植物β多样性变化格局的认识。通过东山岛典型森林林下192个草本样方,以Jaccard相异性指数度量β多样性,结合Mantel检验、偏Mantel检验、依据距离的... 探究植物群落间物种组成差异,有助于深入了解植物β多样性格局及其驱动机制,提高对海岛植物β多样性变化格局的认识。通过东山岛典型森林林下192个草本样方,以Jaccard相异性指数度量β多样性,结合Mantel检验、偏Mantel检验、依据距离的冗余分析(db-RDA)、方差分解,量化空间距离、环境因子、物种丰富度对东山岛草本层β多样性及其组分的相对贡献。结果表明:草本层整体β多样性均值为0.822,周转组分占92.7%,嵌套组分占7.3%,物种间的组成差异主要源于物种更替。在0~30 km尺度内,整体β多样性及周转组分随空间距离呈极显著递增,嵌套组分随距离增加而降低。Mantel及偏Mantel检验结果显示,空间距离及环境因素与周转组分呈极显著相关,嵌套组分仅与物种丰富度呈极显著正相关。db-RDA分析结果表明,周转组分主要由海拔因子驱动,嵌套组分则几乎完全由物种丰富度差异决定。方差分解结果进一步显示,空间距离单独解释4.0%整体β多样性的变异来源,环境因子则单独解释1.9%,二者联合解释2.6%。 展开更多
关键词 Β多样性 环境过滤 扩散限制 草本层 东山岛
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冯福海运用扶正祛邪法治疗类风湿关节炎特色对药介绍
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作者 王子华 李松伟 +7 位作者 杜萌萌 郭洪涛 李纪高 傅文 王荷珺 李桓 刘瑞林 史栋梁 《新中医》 2026年第2期144-148,共5页
介绍冯福海教授运用扶正祛邪法治疗类风湿关节炎的特色对药。冯福海教授认为,类风湿关节炎的核心病机为正气不足、外邪入侵,治当扶正祛邪,擅长运用对药组方配伍治疗,以黄芪-薏苡仁益气渗湿、固脾清痹,千年健-钻地风补肝肾强筋骨、通络除... 介绍冯福海教授运用扶正祛邪法治疗类风湿关节炎的特色对药。冯福海教授认为,类风湿关节炎的核心病机为正气不足、外邪入侵,治当扶正祛邪,擅长运用对药组方配伍治疗,以黄芪-薏苡仁益气渗湿、固脾清痹,千年健-钻地风补肝肾强筋骨、通络除痹,当归-红花补血养血、活血通痹,五加皮-防己利水消肿、补筋利痹,穿山龙-鬼箭羽活血化瘀、通经活络。诊疗强调辨病辨证结合,对药配伍注重正邪、虚实兼顾。 展开更多
关键词 类风湿关节炎 对药 冯福海
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尤昭玲运用固涩药治疗女性生殖系统疾病经验介绍
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作者 庞卓超 尤昭玲 +2 位作者 张海童 杨雨晨 唐诗 《新中医》 2026年第2期129-135,共7页
尤昭玲教授临证时精准辨证施治,灵活运用莲类药、炭类药以及有固肾涩精、收敛固涩、重镇收敛等功效的固涩药治疗多囊卵巢综合征、子宫肌瘤、子宫假腔等多种女性生殖系统疾病,既能收敛病灶、止血,又可起到协助消积除癥的作用,在长期临床... 尤昭玲教授临证时精准辨证施治,灵活运用莲类药、炭类药以及有固肾涩精、收敛固涩、重镇收敛等功效的固涩药治疗多囊卵巢综合征、子宫肌瘤、子宫假腔等多种女性生殖系统疾病,既能收敛病灶、止血,又可起到协助消积除癥的作用,在长期临床实践中已取得良好疗效。 展开更多
关键词 女性生殖系统疾病 莲类药 炭类药 固涩药 尤昭玲
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中药材高质量发展的伦理分析:概念诠释、内涵演变与治理方略
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作者 张燕 《南京师大学报(社会科学版)》 北大核心 2026年第1期159-168,共10页
当前,中药材质量问题频出,作为高质量中药材代表的道地药材质量也无法得到保障。学界对“道地药材”概念的诠释过于偏重科学解释,忽略了对其哲学伦理学内涵的诠释。道地药材的伦理内涵可以从形成发展之“道”、遣方用药之“道”、技艺... 当前,中药材质量问题频出,作为高质量中药材代表的道地药材质量也无法得到保障。学界对“道地药材”概念的诠释过于偏重科学解释,忽略了对其哲学伦理学内涵的诠释。道地药材的伦理内涵可以从形成发展之“道”、遣方用药之“道”、技艺之“道”和评价之“道”四个方面诠释。诠释道地药材的伦理内涵,有助于厘清道地药材在生产、使用、评价体系构建与人才培养等环节出现的伦理问题和发展困境;并在此基础上,提出推动中药材高质量发展的伦理治理策略与实践路径,以期为中药材高质量发展构建更为全面的解决方案。 展开更多
关键词 道地药材 标识性概念 伦理内涵 高质量发展
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道地药材类标准知识模型构建
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作者 高博 何心如 +2 位作者 聂莹 贾李蓉 李静 《中国医药导报》 2026年第2期18-23,共6页
目的针对中药类标准查找难、使用难的现状,建立中药类标准知识模型。方法以道地药材类标准为例,深入探索道地药材类标准的知识结构,采用本体表示方法构建道地药材类标准的知识模型,并将道地药材类标准的知识模型与地理标志产品类标准(... 目的针对中药类标准查找难、使用难的现状,建立中药类标准知识模型。方法以道地药材类标准为例,深入探索道地药材类标准的知识结构,采用本体表示方法构建道地药材类标准的知识模型,并将道地药材类标准的知识模型与地理标志产品类标准(仅限中药材标准)的知识模型进行映射。结果该模型包含10个类、10种类间关系、5种数据属性,并通过实例“怀山药”(T/CACM 2020.5-2019)进行验证,确保了知识模型的科学性和实用性。结论通过中药类标准的知识建模和映射比较研究,能够提高中药类标准在语义上的一致性,及时发现中药类标准体系中的冲突、缺失和薄弱环节,挖掘中药类标准体系的空白领域和新兴需求,从而推动中药产业高质量发展。 展开更多
关键词 标准数字化 道地药材 知识模型
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从百草园到三味书屋再到未来学校:儿童教育空间的变迁与审思
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作者 胥兴春 张媛 《教育与教学研究》 2026年第2期24-37,共14页
从“百草园”到“三味书屋”呈现出鲁迅童年时期所历经的两大教育空间。“百草园”被誉为“儿童的乐园”,它营造出了诗意的教育空间,即“自然与人文并存”的物质空间、“想象与诗意共栖”的精神空间和“自主与创造同在”的社会空间;而... 从“百草园”到“三味书屋”呈现出鲁迅童年时期所历经的两大教育空间。“百草园”被誉为“儿童的乐园”,它营造出了诗意的教育空间,即“自然与人文并存”的物质空间、“想象与诗意共栖”的精神空间和“自主与创造同在”的社会空间;而“三味书屋”作为当时的正统学堂,一定程度上呈现出“功利化”取向,主要体现为“封闭与异化滋生”的物质空间、“规训与压迫显现”的精神空间和“权力与话语倾斜”的社会空间。基于对从“百草园”到“三味书屋”的教育空间变迁的审思,需要探索走向“未来学校”的新型教育空间,具体体现为“破除壁垒的泛在时空”的物质空间、“儿童自主的个性教育”的精神空间和“自由平等的权利关系”的社会空间,这是新型儿童教育空间发展的必然走向。 展开更多
关键词 儿童教育空间 百草园 三味书屋 未来学校 物质空间 精神空间 社会空间
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基于古籍医案的乳腺癌用药规律研究
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作者 张文风 李洺杭 +1 位作者 魏岩 马源 《长春中医药大学学报》 2026年第1期1-7,共7页
目的 基于古籍医案探讨乳腺癌用药规律研究,为现代中医临床辨治及新药研发提供数据支撑与理论参考。方法 通过检索《中华医典》《中华医方·妇科篇》等数据库共得到84部中医古籍中记载的146首治疗乳岩方剂,中药227味,建立中药数据库... 目的 基于古籍医案探讨乳腺癌用药规律研究,为现代中医临床辨治及新药研发提供数据支撑与理论参考。方法 通过检索《中华医典》《中华医方·妇科篇》等数据库共得到84部中医古籍中记载的146首治疗乳岩方剂,中药227味,建立中药数据库后,运用中医传承辅助平台(V3.5)进行频次统计、性味归经、关联规则及聚类分析。结果 高频药物包括当归、甘草、白芍、柴胡、川芎;药性以寒、温为主,药味以苦、甘、辛为多;主归肝、脾、肺经;功效以补虚、清热、理气为要。关联规则显示“白芍,川芎→当归”等核心组合。聚类分析提炼出5个核心类方,涵盖疏肝养血、化痰消癥、破气散结、和解少阳等治法。结论 古代文献中乳腺癌治疗呈现“攻补兼施、标本同治、阴阳并调”的配伍规律,以疏肝理气、化痰消癥为核心,兼顾益气养血,重视情志调摄与脏腑协调,可为中医临床治疗乳腺癌的各个阶段选方用药提供借鉴。 展开更多
关键词 乳腺癌 方药规律 中医辨治
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鸡骨草抗大口黑鲈虹彩病毒作用及其发酵物对鳜保护效果分析
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作者 刘励聪 王玥 +7 位作者 王蕊 王英英 张德锋 王亚军 陈建酬 李新宇 朱学芝 刘丽燕 《淡水渔业》 北大核心 2026年第2期79-89,共11页
为筛选出抗大口黑鲈虹彩病毒(LMBV)的中草药并探究其对鳜的抗病毒效果,本研究选取了土茯苓(Smilax glabra Roxb)、鸡骨草(Abrus herb)、荷叶(Nelumbinis folium)、连翘(Forsythin suspensa)、金银花(Lonicera japonica Thunb.)、杜仲(Eu... 为筛选出抗大口黑鲈虹彩病毒(LMBV)的中草药并探究其对鳜的抗病毒效果,本研究选取了土茯苓(Smilax glabra Roxb)、鸡骨草(Abrus herb)、荷叶(Nelumbinis folium)、连翘(Forsythin suspensa)、金银花(Lonicera japonica Thunb.)、杜仲(Eucommia ulmoides)、蒲公英(Taraxacum mongolicum)、五味子(Schisandra chinensis)、鱼腥草(Houttuynia cordata Thunb.)、金钱草(Dichondra micrantha Urban.)10味中草药对LMBV进行了体外抗病毒实验,并挑选抗LMBV效果较好的鸡骨草单独或与贝莱斯芽孢杆菌GY65联合进行了鱼体实验。结果显示:(1)鸡骨草表现出对LMBV较好的阻断、杀灭作用。(2)GY65发酵鸡骨草水提液后可提高其总黄酮含量14.10%、总酚含量5.64%。(3)攻毒第7天,GY65发酵鸡骨草水提液组(ZG)鳜死亡率最低(20.83%),显著低于对照组(37.5%)。(4)组织学分析表明,鸡骨草水提液及其发酵物可有效减轻LMBV对鳜肠道和肝脏损伤,并上调补体成分3(C3)、免疫球蛋白M(IgM)、白介素8(IL-8)的含量。研究表明,鸡骨草水提液具有较强的抗LMBV作用,经贝莱斯芽孢杆菌GY65发酵后效果更佳。 展开更多
关键词 鸡骨草(Abrus herb) 大口黑鲈虹彩病毒 鳜(Siniperca chuatsi) 芽孢杆菌 抗病毒作用 发酵物
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Study on the Effects of Chinese Herb Additive on Milk Yield and Anti-heat Stress Ability of Holstein Cow 被引量:21
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作者 赵政 陈学文 李仕坚 《Agricultural Science & Technology》 CAS 2008年第3期111-114,共4页
[Objective] The research aimed to explore the effects of Chinese herb additive on milk yield and anti-heat stress ability of Holstein cow.[Method] 36 Holstein cows with similar birth order and milk yield were equally ... [Objective] The research aimed to explore the effects of Chinese herb additive on milk yield and anti-heat stress ability of Holstein cow.[Method] 36 Holstein cows with similar birth order and milk yield were equally and randomly divided into 3 groups which were control group, Chinese medicine Ⅰ group and Chinese medicine Ⅱ group. In control group, cows were fed with basic feed, while in Chinese medicine Ⅰ group, cows were fed with basic feed containing 4% compound Chinese herb additive and in Chinese medicine Ⅱ group, cows were fed with basic feed containing 3% compound Chinese herb additive.All cows in the 3 groups were analyzed comparatively.[Result] Adding some compound Chinese herb additive into basic feed would increase milk yield and anti-heat stress ability of Holstein cow,besides,it also could decrease cow diseases such as cow mastitis.Chinese medicine Ⅰ would generate the highest economic benefit of practical production.[Conclusion] Adding Chinese herb additive into basic feed is an effective way for reliefing heat stress and increasing milk yield. 展开更多
关键词 Chinese herb ADDITIVE HOLSTEIN COW Milk yield Anti-heat stress
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A Survey of the Pteridophyte Herbs of Hainan Island 被引量:22
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作者 杨逢春 梁淑云 《Agricultural Science & Technology》 CAS 2008年第5期136-141,共6页
There are almost 400 species(containing 8 varieties)of pteridophytes on Hainan Island,belonging to 43 families and 114 genera,one third of which are officinal.To understand the distribution of pteridophytes resources ... There are almost 400 species(containing 8 varieties)of pteridophytes on Hainan Island,belonging to 43 families and 114 genera,one third of which are officinal.To understand the distribution of pteridophytes resources of Hainan Island,we conducted this survey mainly by photographing the habitat,plant morphology,sorus and specific traits of some pteridophytes.The results showed that nearly 32 families and 94 species were recorded.These pteridophyte herb resources play important roles in medical treatment of native Li nationality people. 展开更多
关键词 HAINAN ISLAND PTERIDOPHYTE herbS SURVEY
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