Malformations of cortical development(MCDs)represent one of the most common causes of childhood-onset epilepsy,and are often refractory to antiseizure medications(Guerrini,2006;Guerrini and Dobyns,2014;Severino et al....Malformations of cortical development(MCDs)represent one of the most common causes of childhood-onset epilepsy,and are often refractory to antiseizure medications(Guerrini,2006;Guerrini and Dobyns,2014;Severino et al.,2020).Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy(MOGHE)is a newly recognized subtype of Focal Cortical Dysplasia(FCD),which was officially added to the FCD classification in 2022 by the International League Against Epilepsy(ILAE)(Najm et al.,2022).展开更多
基金support from the following grants:the Natural Science Foundation of Beijing Municipality(7242149,L202034,7244416)the E-Town Cooperation&Development Foundation(YCXJ-JZ-2023-017)+3 种基金the National Natural Science Foundation of China(82171694,81901155)National High Level Hospital Clinical Research Funding(High Quality Clinical Research Project of Peking University First Hospital)(23cz020202)National High Level Hospital Clinical Research Funding(Youth Clinical Research Project of Peking University First Hospital)(2023YC19)National High Level Hospital Clinical Research Funding(Scientific Research Seed Fund of Peking University First Hospital)(2023SF42).
文摘Malformations of cortical development(MCDs)represent one of the most common causes of childhood-onset epilepsy,and are often refractory to antiseizure medications(Guerrini,2006;Guerrini and Dobyns,2014;Severino et al.,2020).Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy(MOGHE)is a newly recognized subtype of Focal Cortical Dysplasia(FCD),which was officially added to the FCD classification in 2022 by the International League Against Epilepsy(ILAE)(Najm et al.,2022).