The incorporation of small fluorinated functional groups,including CF_(3),CF_(2)H,and CFH_(2),into small molecules represents a crucial strategy for modulating their physical,chemical,and biological characteristics[1,...The incorporation of small fluorinated functional groups,including CF_(3),CF_(2)H,and CFH_(2),into small molecules represents a crucial strategy for modulating their physical,chemical,and biological characteristics[1,2].Consequently,organofluorine compounds are frequently encountered in pharmaceuticals and agrochemicals.Significant advances have been made in the introduction of fluoroalkyl groups into small molecules since the beginning of the 21st century.展开更多
基金supported by the National Natural Science Foundation of China(22378205)the Priority Academic Program Development of Jiangsu Higher Education Institutionsthe Center for Advanced Materials and Technology in Nanjing University of Science and Technology。
文摘The incorporation of small fluorinated functional groups,including CF_(3),CF_(2)H,and CFH_(2),into small molecules represents a crucial strategy for modulating their physical,chemical,and biological characteristics[1,2].Consequently,organofluorine compounds are frequently encountered in pharmaceuticals and agrochemicals.Significant advances have been made in the introduction of fluoroalkyl groups into small molecules since the beginning of the 21st century.