A simple semi-empirical analysis method for predicting the group effect of pile group under dragload embedded in clay was described assuming an effective influence area around various locations of pile group. Various ...A simple semi-empirical analysis method for predicting the group effect of pile group under dragload embedded in clay was described assuming an effective influence area around various locations of pile group. Various pile and soil parameters such as the array of pile group, spacing of the piles (S), embedment length to diameter ratio of piles (L/D) and the soil properties such as density (γ), angle of internal friction (φ) and pile-soil interface friction coefficient (μ) were considered in the analysis. Model test for dragload of pile group on viscosity soil layer under surface load consolidation conditions was studied. The variations of dragload of pile, resistance of pile tip and the layered settlement of soil with consolidation time were measured. In order to perform comparative analysis, single pile was tested in the same conditions. The predicted group effect values of pile group under dragload were then compared with model test results carried out as a part of the present investigation and also with the values reported in literatures. The predicted values were found to be in good agreement with the measured values, validating the developed analysis method. The model test results show that negative skin friction of pile shaft will reach 80%-90% of its maximum value, when pile-soil relative displacement reaches 2 mm.展开更多
In this work, we focus on assessing the group effect of localized corrosion on the ultimate strength of the marine structural plates and study the load-deformation behaviors of plates of various slenderness and uniaxi...In this work, we focus on assessing the group effect of localized corrosion on the ultimate strength of the marine structural plates and study the load-deformation behaviors of plates of various slenderness and uniaxial compression.Meanwhile, we investigate different corroded patterns from a single circular pit to 25 circular pits distributed over the plate and carry out hundreds of nonlinear finite element simulations by combining the number, depth, distribution of pits with imperfections and slenderness of plate. The distribution of multiple pits causes scattering of stress concentration on the plate, then the plastic section of plate changes with wider distribution of damage simultaneously. The ultimate strength arises when un-loading zone comprised of the yielding strips and holes extends across the plate. It can be concluded that the corroded condition defined as group effect of pits manipulates the deformation state and the loading capacity of plate at the ultimate strength mode that coincides with the proportion of effective loading area and section in the process of post-buckling. To validate the effect of pits group, we perform the numerical experiments of the post-buckling of steel plates containing pits in a row with different orientation.展开更多
As a novel type of foundation in beach and shallow sea, the bucket structure is especially suitable for complex conditions such as soft clay ground and the worse types of sea environments. In this paper, the bearing c...As a novel type of foundation in beach and shallow sea, the bucket structure is especially suitable for complex conditions such as soft clay ground and the worse types of sea environments. In this paper, the bearing capacity of a multi-bucket structure is studied by experiments with a single bucket and four-bucket foundation in a saturated sand layer. Based on the experimental data and numerical analysis results, the bearing capacity behavior and the bucket group effect are compared and analyzed. Furthermore, some influential factors, such as the soil type, the ratio of length to diameter L/D, the ratio of the bucket spacing to the bucket diameter S/D, and the bucket number are introduced and their effects on the multi-bucket structural capacity are investigated. The vertical static capacity adjustment factor is introduced to evaluate the bucket group effects of the multi-bucket foundation.展开更多
With the hypothesis of simple units integration to create new reactivities,a strategy for the synthesis of polyfunctionalized 5-alkenyl-3-carbonylfurans fromγ-hydroxyl enal and 1,3-dicarbonyl compounds is established...With the hypothesis of simple units integration to create new reactivities,a strategy for the synthesis of polyfunctionalized 5-alkenyl-3-carbonylfurans fromγ-hydroxyl enal and 1,3-dicarbonyl compounds is established,featuring readily available starting materials,high efficiency,good functional groups compatibility,green chemistry with high atom economy and only water release,etc.,to provide a series of polyfunctionalized 5-alkenyl-3-carbonylfurans,which could be applied to the late-stage functionalization of naturally occurring compounds and bioactive molecules,as well as the transformation to pyrroles and polycyclic aromatic hydrocarbon via electrocyclic reaction.Theγ-hydroxyl has played an important role in the unexpected process of ring opening isomerization of 2H-pyran to furanones,as confirmed by detailed mechanistic studies.展开更多
The present study was designed to investigate the antithrombotic effects and underlying mechanisms of the effective components group(ECG) of Xiaoshuantongluo recipe(XECG) and to further verify the rationality and feas...The present study was designed to investigate the antithrombotic effects and underlying mechanisms of the effective components group(ECG) of Xiaoshuantongluo recipe(XECG) and to further verify the rationality and feasibility of ECG-guided methodology in traditional Chinese medicine(TCM) research. The arterial thrombosis model induced by ferric chloride(FeC l3) oxidation and the venous thrombosis model induced by inferior vena cava ligation were established to evaluate the antithrombotic potential of XECG. Our results indicated that XECG significantly prolonged the time to occlusion, activated partial thromboplastin time(APTT), and prothrombin time(PT), and markedly inhibited adenosine diphosphate(ADP)-induced platelet aggregation in the 20% Fe Cl3-induced arterial thrombosis model. The superoxide dismutase(SOD) activity was significantly increased and the levels of malondialdehyde(MDA) and nitric oxide(NO) were dramatically decreased in the plasma of arterial thrombosis rats after XECG treatment for 12 days. Furthermore, XECG markedly reduced the weight of thrombus formed by inferior vena cava ligation. Additionally, XECG exhibited 2,2-diphenyl-1-picrylhydrazyl(DPPH) free radical scavenging activity and protective effect on mitochondrial lipid peroxidation. In summary, XECG played an important role in the prevention of thrombosis through interacting with multiple targets, including inhibition of platelet aggregation and coagulation and repression of oxidative stress. The ECG-guided methodology was validated as a feasible tool in TCM research.展开更多
Vigilance behavior is considered as an effective strategy for prey species to detect predators.An individual benefits from living in a group by reducing the time spent being vigilant without affecting the probability ...Vigilance behavior is considered as an effective strategy for prey species to detect predators.An individual benefits from living in a group by reducing the time spent being vigilant without affecting the probability of detecting a predator.However,the mechanism producing a decrease in vigilance with increasing group size is unclear.Many models of vigilance assume that group members scan independently of one another.Yet in recent studies,the other 2 patterns of vigilance,coordination and synchronization,were reported in some species.In 2 summers(2018 and 2019),we studied the group-size effect on vigilance and foraging of Tibetan wild ass in Chang Tang Nature Reserve of Tibet.We also tested whether individuals scan the environment independently,tend to coordinate their scans,or tend to synchronize their vigilance.The results showed that individuals decreased the time spent on vigilance with increasing group size,while increased the time spent foraging.Group members scanned the environment at the same time more frequently and there was a positive correlation between group members'behaviors,indicating that Tibetan wild asses tend to synchronize their vigilance.展开更多
The interfacial defects and energy barrier are main reasons for interfacial nonradiative recombination.In addition,poor perovskite crystallization and incomplete conversion of PbI_(2) to perovskite restrict further en...The interfacial defects and energy barrier are main reasons for interfacial nonradiative recombination.In addition,poor perovskite crystallization and incomplete conversion of PbI_(2) to perovskite restrict further enhancement of the photovoltaic performance of the devices using sequential deposition.Herein,a buried interface stabilization strategy that relies on the synergy of fluorine(F)and sulfonyl(S=O)functional groups is proposed.A series of potassium salts containing halide and non-halogen anions are employed to modify SnO_(2)/perovskite buried interface.Multiple chemical bonds including hydrogen bond,coordination bond and ionic bond are realized,which strengthens interfacial contact and defect passivation effect.The chemical interaction between modification molecules and perovskite along with SnO_(2) heightens incessantly as the number of S=O and F augments.The chemical interaction strength between modifiers and perovskite as well as SnO_(2) gradually increases with the increase in the number of S=O and F.The defect passivation effect is positively correlated with the chemical interaction strength.The crystallization kinetics is regulated through the compromise between chemical interaction strength and wettability of substrates.Compared with Cl−,all non-halogen anions perform better in crystallization optimization,energy band regulation and defect passivation.The device with potassium bis(fluorosulfonyl)imide achieves a tempting efficiency of 24.17%.展开更多
The European Union(EU) and Organisation for Economic Co-operation and Development(OECD) aim to develop long-term policies for their respective member countries. Having observed increasing dangers to the environment po...The European Union(EU) and Organisation for Economic Co-operation and Development(OECD) aim to develop long-term policies for their respective member countries. Having observed increasing dangers to the environment posed by rising economic growth, they are seeking pathways to enable policy action on economic growth and environmental sustainability. Given the facts in theoretical and empirical studies, this study assessed the validity of the decoupling hypothesis by investigating asymmetricity in the relationship between environmental sustainability and economic growth in nine Eastern European countries from 1998 to 2017 using the cross-section augmented Dickey-Fuller(CADF) unit root, panel corrected standard error(PCSE), common correlated effect mean group(CCEMG), and Dumitrescu Hurlin causality approaches. Both population growth and drinking water are used as controlled variables. The outcomes establish strong cointegration among all the variables of interest. According to the results of CCEMG test, economic growth exerts short-term environmental degradation but has long-term environmental benefits in Eastern Europe;and population growth and drinking water exert a positive effect on environmental sustainability in both the short-and long-run. The results of Dumitrescu Hurlin causality test indicate that environmental sustainability is unidirectionally affected by economic growth. Based on these outcomes, we suggest the following policies:(1) the EU and OECD should implement member-targeted policies on economic growth and fossil-fuel use towards regulating industrial pollution, water use, and population control;and(2) the EU and OECD member countries should invest in environmental technologies through green research and development(R&D) to transform their dirty industrial processes and ensure productive energy use.展开更多
This paper aims to study the mathematical properties of the l vmodels that employ measurement matrices with correlated columns.We first show that the l_(1-2)model satisfies the grouping effect which ensures that coeff...This paper aims to study the mathematical properties of the l vmodels that employ measurement matrices with correlated columns.We first show that the l_(1-2)model satisfies the grouping effect which ensures that coefficients corresponding to highly correlated columns in a measurement matrix have small differences.Then we provide the stability analysis based on the sparse approximation property.When the entries of the vectors have different signs,we show that the grouping effect also holds for the constraint l_(1-2)minimization model which is implicated by the linearized Bregman iteration.展开更多
This is a case research on group work and the aim is to investigate the effectiveness of group work in English teaching in English major of Zhejiang Guangsha College of Applied Construction Technology(ZGC).By carrying...This is a case research on group work and the aim is to investigate the effectiveness of group work in English teaching in English major of Zhejiang Guangsha College of Applied Construction Technology(ZGC).By carrying out a 15-week experiment on 08 Applied English Class 1 and 2,questionnaires on 08 Business English Class 1-5(213 students),and interviews on 22 teachers of English major,the research results show and prove that group work is often performed in ZGC and group work is quite effective in English teaching.展开更多
This study presents a numerical simulation of large-scale shaking table tests on a superstructure supported by a pile group installed in an inclined liquefiable site,fo-cusing on nonlinear interactions between piles a...This study presents a numerical simulation of large-scale shaking table tests on a superstructure supported by a pile group installed in an inclined liquefiable site,fo-cusing on nonlinear interactions between piles and the soil.A three-dimensional finite element model of a soil-pile superstructure system is developed using OpenSeesMP.The temporal and spatial evolution of the radial soil pressure around the pile is evaluated in both liquefied and nonlique-fied sites.Results show that the soil pressure around the pile is significantly influenced by site inclination and soil lateral spreading.In liquefied sites,the soil pressure in the ex-truded zone of the upstream pile is significantly higher than that in the diffused zone.However,higher pressure occurs in the diffused zone for nonliquefied sites.Correspond-ingly,the liquefaction state significantly influences the force characteristics of the pile group system.Additionally,the group effect is more pronounced in liquefied sites.The results also indicate that the soil pressure distribution around the piles is closely related to the relative pile-soil displace-ment and reveals different on-pile force mechanisms under varying site conditions.These findings offer valuable in-sights into the seismic design of pile foundations in inclined liquefied sites.展开更多
This paper aims to present a theoretical method to study the bearing performance of vertically loaded large-diameter pipe pile groups.The interactions between group piles result in different bearing performance of bot...This paper aims to present a theoretical method to study the bearing performance of vertically loaded large-diameter pipe pile groups.The interactions between group piles result in different bearing performance of both a single pile and pile groups.Considering the pile group effect and the skin friction from both outer and inner soils,an analytical solution is developed to calculate the settlement and axial force in large-diameter pipe pile groups.The analytical solution was verified by centrifuge and field testing results.An extensive parametric analysis was performed to study the bearing performance of the pipe pile groups.The results reveal that the axial forces in group piles are not the same.The larger the distance from central pile,the larger the axial force.The axial force in the central pile is the smallest,while that in corner piles is the largest.The axial force on the top of the corner piles decreases while that in the central pile increases with increasing of pile spacing and decreasing of pile length.The axial force in side piles varies little with the variations of pile spacing,pile length,and shear modulus of the soil and is approximately equal to the average load shared by one pile.For a pile group,the larger the pile length is,the larger the influence radius is.As a result,the pile group effect is more apparent for a larger pile length.The settlement of pile groups decreases with increasing of the pile number in the group and the shear modulus of the underlying soil.展开更多
An empirical approach has been developed to analyze the nonlinear response of a pile group with arbitrarily distributed piles subjected to combined lateral and torsional loading.In this approach,the concept of instant...An empirical approach has been developed to analyze the nonlinear response of a pile group with arbitrarily distributed piles subjected to combined lateral and torsional loading.In this approach,the concept of instantaneous twist center is applied to analyze the displacement relationship of pile heads and establish the static equilibrium equations of the pile cap.The horizontal interaction among the individual piles is considered through the generalized p-multiplier.The coupling effect of lateral resistance on the torsional resistance of each pile is quantified using an empirical factorβ;the lateral and torsional nonlinear responses of individual piles are modeled by p-y andτ-θcurves,respectively.The proposed approach not only captures the most significant aspect of the group effect and coupling effect in a pile group subjected to combined lateral and torsional loading,but also automatically updates p-multipliers of individual piles based on pile cap displacements.The proposed approach was verified using results of model tests on pile groups subjected to lateral loading,torsional loading,and combined lateral and torsional loading,separately.In general,the pile cap response and the transfer of applied loads in the pile groups agree well with the test results.展开更多
A new approach was proposed for grouping separation of 14 lanthanide rare-earth ions from their coexisting mixed aqueous solutions, by performing liquid-column elution using the aqueous solution containing 14 lanthani...A new approach was proposed for grouping separation of 14 lanthanide rare-earth ions from their coexisting mixed aqueous solutions, by performing liquid-column elution using the aqueous solution containing 14 lanthanide rare-earth ions as the stationary phase and the dispersed organic oil droplets containing P507 extractant as the mobile phase. It was revealed that 14 lanthanide rare-earth ions could be separated into four groups, according to the lanthanide tetrad effect, respectively eluting out from the liquid column at different time in a certain order. Various effects including the saponification degree of P507, the concentration of P507 in organic phase, the length and inner diameter of the extraction column on the performance of grouping separation of rare-earth ions were discussed. The changes of the mass transfer coefficients were also investigated. The separation efficiency of the four groups of rareearth elements(REEs) was evaluated based on the elution resolution, Rs, of the elution peaks of La(Ⅲ),Gd(Ⅲ), Ho(Ⅲ) and Lu(Ⅲ), the four representative elements respectively from each of the four groups of REEs. Experimental results demonstrated that the separation of REEs by liquid-column elution mainly depended on the competitive adsorption of different rare-earth groups onto the surface of ascending P507 oil droplets. The affinity of different rare-earth groups with P507 extractant and a limited adsorption capacity of P507 molecules at the surface of the oil droplets ascending in liquid column play the important role. The present work highlights a promising technique for grouping separation of multiple lanthanide elements co-existing complex systems.展开更多
AlCl3-mediated cleavage of ethereal methyl–oxygen bond in aroylated 2,7-dimethoxynaphthalene compounds proceeds chemospecifically and regioselectively. The ethereal bond at the β(2)-position of 1-monoaroylated 2,7-d...AlCl3-mediated cleavage of ethereal methyl–oxygen bond in aroylated 2,7-dimethoxynaphthalene compounds proceeds chemospecifically and regioselectively. The ethereal bond at the β(2)-position of 1-monoaroylated 2,7-dimethoxynaphthalene is cleaved readily and predominantly against the β(7)-position, whereas scission of β-ethereal bonds of 1,8-diaroylated 2,7-dimethoxynaphthalene hardly undergoes like the non-aroylated mother frame compound of 2,7-dimethoxynaphthalene.展开更多
High mobility group box 1 protein （HMGB1） is a highly conserved, ubiquitous protein in the nuclei and cytoplasm of nearly all cell types. HMGB1 is secreted into the extracellular milieu and acts as a proinflammatory...High mobility group box 1 protein （HMGB1） is a highly conserved, ubiquitous protein in the nuclei and cytoplasm of nearly all cell types. HMGB1 is secreted into the extracellular milieu and acts as a proinflammatory cytokine. In this article we reviewed briefly the cellular immune response mediated by HMGB1 in inflammation and sepsis. This systemic review is mainly based on our own work and other related reports HMGB1 can actively affect the immune functions of many types of cells including T lymphocytes, regulatory T cells （Tregs）, dendritic cells （DCs）, macrophages, and natural killer cells （NK cells）. Various cellular responses can be mediated by HMGB1 which binds to cell-surface receptors [e.g., the receptor for advanced glycation end products （RAGE）, Toll-like receptor （TLR）2, and TLR4]. Anti-HMGB1 treatment, such as anti-HMGB1 polyclonal or monoclonal antibodies, inhibitors （e.g., ethyl pyruvate） and antagonists （e.g., A box）, can protect against sepsis lethality and give a wider window for the treatment opportunity. HMGB1 is an attractive target for the development of new therapeutic strategies in the treatment of patients with septic complications.展开更多
We have calculated the transport properties of electron through an artificial quantum dot by using the numerical renormalization group technique in this paper. We obtain the conductance for the system of a quantum dot...We have calculated the transport properties of electron through an artificial quantum dot by using the numerical renormalization group technique in this paper. We obtain the conductance for the system of a quantum dot which is embedded in a one-dimensional chain in zero and finite temperature cases. The external magnetic field gives rise to a negative magnetoconductance in the zero temperature case. It increases as the external magnetic field increases, We obtain the relation between the coupling coefficient and conductance. If the interaction is big enough to prevent conduction electrons from tunnelling through the dot, the dispersion effect is dominant in this case. In the Kondo temperature regime, we obtain the conductivity of a quantum dot system with Kondo correlation.展开更多
The Wilsonian renormalization group approach to the Lippmann-Schwinger equation with a multitude of cutoff parameters is introduced.A system of integro-differential equations for the cutoff-dependent potential is obta...The Wilsonian renormalization group approach to the Lippmann-Schwinger equation with a multitude of cutoff parameters is introduced.A system of integro-differential equations for the cutoff-dependent potential is obtained.As an illustration,a perturbative solution of these equations with two cutoff parameters for a simple case of an S-wave low-energy potential in the form of a Taylor series in momenta is obtained.The relevance of the obtained results for the effective field theory approach to nucleon-nucleon scattering is discussed.展开更多
In the present paper two contents are enclosed .First ,the Fourier analysis approach of the dispersion relation and group velocity effect of finite difference schemes is discussed.the defects of the approach is pointe...In the present paper two contents are enclosed .First ,the Fourier analysis approach of the dispersion relation and group velocity effect of finite difference schemes is discussed.the defects of the approach is pointed out and the correction is made;Second,a new systematic analysis method -remaider -effect analysis (abbr.REAM)is proposed by means of the modified partial differential equations (abbr MPDE)of finite difference schemes.The analysis is based on the synthetical study of the rational dispersion-and dissipation relations of finite difference schemes.And the method clearly possesses constructivity展开更多
基金Project(50679015) supported by the National Natural Science Foundation of China
文摘A simple semi-empirical analysis method for predicting the group effect of pile group under dragload embedded in clay was described assuming an effective influence area around various locations of pile group. Various pile and soil parameters such as the array of pile group, spacing of the piles (S), embedment length to diameter ratio of piles (L/D) and the soil properties such as density (γ), angle of internal friction (φ) and pile-soil interface friction coefficient (μ) were considered in the analysis. Model test for dragload of pile group on viscosity soil layer under surface load consolidation conditions was studied. The variations of dragload of pile, resistance of pile tip and the layered settlement of soil with consolidation time were measured. In order to perform comparative analysis, single pile was tested in the same conditions. The predicted group effect values of pile group under dragload were then compared with model test results carried out as a part of the present investigation and also with the values reported in literatures. The predicted values were found to be in good agreement with the measured values, validating the developed analysis method. The model test results show that negative skin friction of pile shaft will reach 80%-90% of its maximum value, when pile-soil relative displacement reaches 2 mm.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.51490670 and 11572300)R&D Plan(Grant No.2017GHY15120)Fundamental Research Fund for Central Universities(Ocean University of China)
文摘In this work, we focus on assessing the group effect of localized corrosion on the ultimate strength of the marine structural plates and study the load-deformation behaviors of plates of various slenderness and uniaxial compression.Meanwhile, we investigate different corroded patterns from a single circular pit to 25 circular pits distributed over the plate and carry out hundreds of nonlinear finite element simulations by combining the number, depth, distribution of pits with imperfections and slenderness of plate. The distribution of multiple pits causes scattering of stress concentration on the plate, then the plastic section of plate changes with wider distribution of damage simultaneously. The ultimate strength arises when un-loading zone comprised of the yielding strips and holes extends across the plate. It can be concluded that the corroded condition defined as group effect of pits manipulates the deformation state and the loading capacity of plate at the ultimate strength mode that coincides with the proportion of effective loading area and section in the process of post-buckling. To validate the effect of pits group, we perform the numerical experiments of the post-buckling of steel plates containing pits in a row with different orientation.
文摘As a novel type of foundation in beach and shallow sea, the bucket structure is especially suitable for complex conditions such as soft clay ground and the worse types of sea environments. In this paper, the bearing capacity of a multi-bucket structure is studied by experiments with a single bucket and four-bucket foundation in a saturated sand layer. Based on the experimental data and numerical analysis results, the bearing capacity behavior and the bucket group effect are compared and analyzed. Furthermore, some influential factors, such as the soil type, the ratio of length to diameter L/D, the ratio of the bucket spacing to the bucket diameter S/D, and the bucket number are introduced and their effects on the multi-bucket structural capacity are investigated. The vertical static capacity adjustment factor is introduced to evaluate the bucket group effects of the multi-bucket foundation.
基金Financial support from National Natural Science Foundation of China(Grant No.22201187)the starting grant from Capital Medical University(Grant No.3100-12400123)。
文摘With the hypothesis of simple units integration to create new reactivities,a strategy for the synthesis of polyfunctionalized 5-alkenyl-3-carbonylfurans fromγ-hydroxyl enal and 1,3-dicarbonyl compounds is established,featuring readily available starting materials,high efficiency,good functional groups compatibility,green chemistry with high atom economy and only water release,etc.,to provide a series of polyfunctionalized 5-alkenyl-3-carbonylfurans,which could be applied to the late-stage functionalization of naturally occurring compounds and bioactive molecules,as well as the transformation to pyrroles and polycyclic aromatic hydrocarbon via electrocyclic reaction.Theγ-hydroxyl has played an important role in the unexpected process of ring opening isomerization of 2H-pyran to furanones,as confirmed by detailed mechanistic studies.
基金supported by the Major Scientific and Technological Special Project for"Significant New Drugs Creation"(No.2013ZX09508104001002)the National Natural Science Foundation of China(No.81273652)
文摘The present study was designed to investigate the antithrombotic effects and underlying mechanisms of the effective components group(ECG) of Xiaoshuantongluo recipe(XECG) and to further verify the rationality and feasibility of ECG-guided methodology in traditional Chinese medicine(TCM) research. The arterial thrombosis model induced by ferric chloride(FeC l3) oxidation and the venous thrombosis model induced by inferior vena cava ligation were established to evaluate the antithrombotic potential of XECG. Our results indicated that XECG significantly prolonged the time to occlusion, activated partial thromboplastin time(APTT), and prothrombin time(PT), and markedly inhibited adenosine diphosphate(ADP)-induced platelet aggregation in the 20% Fe Cl3-induced arterial thrombosis model. The superoxide dismutase(SOD) activity was significantly increased and the levels of malondialdehyde(MDA) and nitric oxide(NO) were dramatically decreased in the plasma of arterial thrombosis rats after XECG treatment for 12 days. Furthermore, XECG markedly reduced the weight of thrombus formed by inferior vena cava ligation. Additionally, XECG exhibited 2,2-diphenyl-1-picrylhydrazyl(DPPH) free radical scavenging activity and protective effect on mitochondrial lipid peroxidation. In summary, XECG played an important role in the prevention of thrombosis through interacting with multiple targets, including inhibition of platelet aggregation and coagulation and repression of oxidative stress. The ECG-guided methodology was validated as a feasible tool in TCM research.
基金This work was supported by National Natural Science Foundation of China(31772470,41871294)Tibet Major Science and Technology Project(XZ201901-GA-06).
文摘Vigilance behavior is considered as an effective strategy for prey species to detect predators.An individual benefits from living in a group by reducing the time spent being vigilant without affecting the probability of detecting a predator.However,the mechanism producing a decrease in vigilance with increasing group size is unclear.Many models of vigilance assume that group members scan independently of one another.Yet in recent studies,the other 2 patterns of vigilance,coordination and synchronization,were reported in some species.In 2 summers(2018 and 2019),we studied the group-size effect on vigilance and foraging of Tibetan wild ass in Chang Tang Nature Reserve of Tibet.We also tested whether individuals scan the environment independently,tend to coordinate their scans,or tend to synchronize their vigilance.The results showed that individuals decreased the time spent on vigilance with increasing group size,while increased the time spent foraging.Group members scanned the environment at the same time more frequently and there was a positive correlation between group members'behaviors,indicating that Tibetan wild asses tend to synchronize their vigilance.
基金supported by the Defense Industrial Technology Development Program(JCKY2017110C0654)National Natural Science Foundation of China(11974063,61904023,62274018)+1 种基金Chongqing Special Postdoctoral Science Foundation(cstc2019jcyj-bsh0026)Fundamental Research Funds for the Central Universities(2021CDJQY-022).
文摘The interfacial defects and energy barrier are main reasons for interfacial nonradiative recombination.In addition,poor perovskite crystallization and incomplete conversion of PbI_(2) to perovskite restrict further enhancement of the photovoltaic performance of the devices using sequential deposition.Herein,a buried interface stabilization strategy that relies on the synergy of fluorine(F)and sulfonyl(S=O)functional groups is proposed.A series of potassium salts containing halide and non-halogen anions are employed to modify SnO_(2)/perovskite buried interface.Multiple chemical bonds including hydrogen bond,coordination bond and ionic bond are realized,which strengthens interfacial contact and defect passivation effect.The chemical interaction between modification molecules and perovskite along with SnO_(2) heightens incessantly as the number of S=O and F augments.The chemical interaction strength between modifiers and perovskite as well as SnO_(2) gradually increases with the increase in the number of S=O and F.The defect passivation effect is positively correlated with the chemical interaction strength.The crystallization kinetics is regulated through the compromise between chemical interaction strength and wettability of substrates.Compared with Cl−,all non-halogen anions perform better in crystallization optimization,energy band regulation and defect passivation.The device with potassium bis(fluorosulfonyl)imide achieves a tempting efficiency of 24.17%.
文摘The European Union(EU) and Organisation for Economic Co-operation and Development(OECD) aim to develop long-term policies for their respective member countries. Having observed increasing dangers to the environment posed by rising economic growth, they are seeking pathways to enable policy action on economic growth and environmental sustainability. Given the facts in theoretical and empirical studies, this study assessed the validity of the decoupling hypothesis by investigating asymmetricity in the relationship between environmental sustainability and economic growth in nine Eastern European countries from 1998 to 2017 using the cross-section augmented Dickey-Fuller(CADF) unit root, panel corrected standard error(PCSE), common correlated effect mean group(CCEMG), and Dumitrescu Hurlin causality approaches. Both population growth and drinking water are used as controlled variables. The outcomes establish strong cointegration among all the variables of interest. According to the results of CCEMG test, economic growth exerts short-term environmental degradation but has long-term environmental benefits in Eastern Europe;and population growth and drinking water exert a positive effect on environmental sustainability in both the short-and long-run. The results of Dumitrescu Hurlin causality test indicate that environmental sustainability is unidirectionally affected by economic growth. Based on these outcomes, we suggest the following policies:(1) the EU and OECD should implement member-targeted policies on economic growth and fossil-fuel use towards regulating industrial pollution, water use, and population control;and(2) the EU and OECD member countries should invest in environmental technologies through green research and development(R&D) to transform their dirty industrial processes and ensure productive energy use.
基金supported by the Zhejiang Provincial Natural Science Foundation of China(LR19A010001)the NSF of China(12022112)Research of Hu Ruifang was supported by the general research project of Jiaxing Nanhu University(62107YL)。
文摘This paper aims to study the mathematical properties of the l vmodels that employ measurement matrices with correlated columns.We first show that the l_(1-2)model satisfies the grouping effect which ensures that coefficients corresponding to highly correlated columns in a measurement matrix have small differences.Then we provide the stability analysis based on the sparse approximation property.When the entries of the vectors have different signs,we show that the grouping effect also holds for the constraint l_(1-2)minimization model which is implicated by the linearized Bregman iteration.
文摘This is a case research on group work and the aim is to investigate the effectiveness of group work in English teaching in English major of Zhejiang Guangsha College of Applied Construction Technology(ZGC).By carrying out a 15-week experiment on 08 Applied English Class 1 and 2,questionnaires on 08 Business English Class 1-5(213 students),and interviews on 22 teachers of English major,the research results show and prove that group work is often performed in ZGC and group work is quite effective in English teaching.
基金The National Science Fund for Distinguished Young Scholars (No. 52225807)。
文摘This study presents a numerical simulation of large-scale shaking table tests on a superstructure supported by a pile group installed in an inclined liquefiable site,fo-cusing on nonlinear interactions between piles and the soil.A three-dimensional finite element model of a soil-pile superstructure system is developed using OpenSeesMP.The temporal and spatial evolution of the radial soil pressure around the pile is evaluated in both liquefied and nonlique-fied sites.Results show that the soil pressure around the pile is significantly influenced by site inclination and soil lateral spreading.In liquefied sites,the soil pressure in the ex-truded zone of the upstream pile is significantly higher than that in the diffused zone.However,higher pressure occurs in the diffused zone for nonliquefied sites.Correspond-ingly,the liquefaction state significantly influences the force characteristics of the pile group system.Additionally,the group effect is more pronounced in liquefied sites.The results also indicate that the soil pressure distribution around the piles is closely related to the relative pile-soil displace-ment and reveals different on-pile force mechanisms under varying site conditions.These findings offer valuable in-sights into the seismic design of pile foundations in inclined liquefied sites.
基金supported by the Joint High Speed Railway Key Program of National Natural Science Foundation of China (Grant No.U1134207)the National Natural Science Foundation of China (Grant No.51378177)+1 种基金the Program for Excellent University Talents in New Century (Grant No.NCET-12-0843)the Fundamental Research Fund for the Central Universities (Grant No.106112014CDJZR200007)
文摘This paper aims to present a theoretical method to study the bearing performance of vertically loaded large-diameter pipe pile groups.The interactions between group piles result in different bearing performance of both a single pile and pile groups.Considering the pile group effect and the skin friction from both outer and inner soils,an analytical solution is developed to calculate the settlement and axial force in large-diameter pipe pile groups.The analytical solution was verified by centrifuge and field testing results.An extensive parametric analysis was performed to study the bearing performance of the pipe pile groups.The results reveal that the axial forces in group piles are not the same.The larger the distance from central pile,the larger the axial force.The axial force in the central pile is the smallest,while that in corner piles is the largest.The axial force on the top of the corner piles decreases while that in the central pile increases with increasing of pile spacing and decreasing of pile length.The axial force in side piles varies little with the variations of pile spacing,pile length,and shear modulus of the soil and is approximately equal to the average load shared by one pile.For a pile group,the larger the pile length is,the larger the influence radius is.As a result,the pile group effect is more apparent for a larger pile length.The settlement of pile groups decreases with increasing of the pile number in the group and the shear modulus of the underlying soil.
基金Project supported by the National Natural Science Foundation of China(Nos.50809060 and 51579218)the Fundamental Research Funds for the Central Universities,China(No.2011QNA4013)。
文摘An empirical approach has been developed to analyze the nonlinear response of a pile group with arbitrarily distributed piles subjected to combined lateral and torsional loading.In this approach,the concept of instantaneous twist center is applied to analyze the displacement relationship of pile heads and establish the static equilibrium equations of the pile cap.The horizontal interaction among the individual piles is considered through the generalized p-multiplier.The coupling effect of lateral resistance on the torsional resistance of each pile is quantified using an empirical factorβ;the lateral and torsional nonlinear responses of individual piles are modeled by p-y andτ-θcurves,respectively.The proposed approach not only captures the most significant aspect of the group effect and coupling effect in a pile group subjected to combined lateral and torsional loading,but also automatically updates p-multipliers of individual piles based on pile cap displacements.The proposed approach was verified using results of model tests on pile groups subjected to lateral loading,torsional loading,and combined lateral and torsional loading,separately.In general,the pile cap response and the transfer of applied loads in the pile groups agree well with the test results.
基金Supported by the National Natural Science Foundation of China(51574213,51074150)the Key Project of Chinese National Programs for Fundamental Research and Development(2012CBA01203)
文摘A new approach was proposed for grouping separation of 14 lanthanide rare-earth ions from their coexisting mixed aqueous solutions, by performing liquid-column elution using the aqueous solution containing 14 lanthanide rare-earth ions as the stationary phase and the dispersed organic oil droplets containing P507 extractant as the mobile phase. It was revealed that 14 lanthanide rare-earth ions could be separated into four groups, according to the lanthanide tetrad effect, respectively eluting out from the liquid column at different time in a certain order. Various effects including the saponification degree of P507, the concentration of P507 in organic phase, the length and inner diameter of the extraction column on the performance of grouping separation of rare-earth ions were discussed. The changes of the mass transfer coefficients were also investigated. The separation efficiency of the four groups of rareearth elements(REEs) was evaluated based on the elution resolution, Rs, of the elution peaks of La(Ⅲ),Gd(Ⅲ), Ho(Ⅲ) and Lu(Ⅲ), the four representative elements respectively from each of the four groups of REEs. Experimental results demonstrated that the separation of REEs by liquid-column elution mainly depended on the competitive adsorption of different rare-earth groups onto the surface of ascending P507 oil droplets. The affinity of different rare-earth groups with P507 extractant and a limited adsorption capacity of P507 molecules at the surface of the oil droplets ascending in liquid column play the important role. The present work highlights a promising technique for grouping separation of multiple lanthanide elements co-existing complex systems.
文摘AlCl3-mediated cleavage of ethereal methyl–oxygen bond in aroylated 2,7-dimethoxynaphthalene compounds proceeds chemospecifically and regioselectively. The ethereal bond at the β(2)-position of 1-monoaroylated 2,7-dimethoxynaphthalene is cleaved readily and predominantly against the β(7)-position, whereas scission of β-ethereal bonds of 1,8-diaroylated 2,7-dimethoxynaphthalene hardly undergoes like the non-aroylated mother frame compound of 2,7-dimethoxynaphthalene.
基金supported,in part,by grants from the National Natural Science Foundation(Nos.81130035,30901561,30971192,81071545)the National Basic Research Program of China(No.2012CB518102)the China Postdoctoral Science Foundation(Nos.20100480347,201104125)
文摘High mobility group box 1 protein （HMGB1） is a highly conserved, ubiquitous protein in the nuclei and cytoplasm of nearly all cell types. HMGB1 is secreted into the extracellular milieu and acts as a proinflammatory cytokine. In this article we reviewed briefly the cellular immune response mediated by HMGB1 in inflammation and sepsis. This systemic review is mainly based on our own work and other related reports HMGB1 can actively affect the immune functions of many types of cells including T lymphocytes, regulatory T cells （Tregs）, dendritic cells （DCs）, macrophages, and natural killer cells （NK cells）. Various cellular responses can be mediated by HMGB1 which binds to cell-surface receptors [e.g., the receptor for advanced glycation end products （RAGE）, Toll-like receptor （TLR）2, and TLR4]. Anti-HMGB1 treatment, such as anti-HMGB1 polyclonal or monoclonal antibodies, inhibitors （e.g., ethyl pyruvate） and antagonists （e.g., A box）, can protect against sepsis lethality and give a wider window for the treatment opportunity. HMGB1 is an attractive target for the development of new therapeutic strategies in the treatment of patients with septic complications.
基金Project supported by the National Natural Science Foundation of China （Grant Nos 10074029 and 60276005）, and by the State Key Development Program for Basic Research of China （Grant No G1999064509）.
文摘We have calculated the transport properties of electron through an artificial quantum dot by using the numerical renormalization group technique in this paper. We obtain the conductance for the system of a quantum dot which is embedded in a one-dimensional chain in zero and finite temperature cases. The external magnetic field gives rise to a negative magnetoconductance in the zero temperature case. It increases as the external magnetic field increases, We obtain the relation between the coupling coefficient and conductance. If the interaction is big enough to prevent conduction electrons from tunnelling through the dot, the dispersion effect is dominant in this case. In the Kondo temperature regime, we obtain the conductivity of a quantum dot system with Kondo correlation.
基金Supported in part by BMBF under Grant No.05P2015–NUSTAR R&D)DFG and NSFC through Funds Provided to the SinoGerman CRC 110 “Symmetries and the Emergence of Structure in QCD”+2 种基金National Natural Science Foundation of China under Grant No.11621131001,DFG Grant No.TRR110the Georgian Shota Rustaveli National Science Foundation(grant FR/417/6-100/14)the CAS President’s International Fellowship Initiative(PIFI)under Grant No.2017VMA0025
文摘The Wilsonian renormalization group approach to the Lippmann-Schwinger equation with a multitude of cutoff parameters is introduced.A system of integro-differential equations for the cutoff-dependent potential is obtained.As an illustration,a perturbative solution of these equations with two cutoff parameters for a simple case of an S-wave low-energy potential in the form of a Taylor series in momenta is obtained.The relevance of the obtained results for the effective field theory approach to nucleon-nucleon scattering is discussed.
文摘In the present paper two contents are enclosed .First ,the Fourier analysis approach of the dispersion relation and group velocity effect of finite difference schemes is discussed.the defects of the approach is pointed out and the correction is made;Second,a new systematic analysis method -remaider -effect analysis (abbr.REAM)is proposed by means of the modified partial differential equations (abbr MPDE)of finite difference schemes.The analysis is based on the synthetical study of the rational dispersion-and dissipation relations of finite difference schemes.And the method clearly possesses constructivity
