We performed this study to investigate pathological upgrading from biopsy to prostatectomy and clinicopathological factors associated with grade group(GG)upgrading in patients with International Society of Urological ...We performed this study to investigate pathological upgrading from biopsy to prostatectomy and clinicopathological factors associated with grade group(GG)upgrading in patients with International Society of Urological Pathology(ISUP)GG 1 and 2 prostate cancer(PCa)in a Chinese cohort.We included patients diagnosed with PCa with ISUP GG 1 and 2 at biopsy,who underwent RP at our institution.Pre-and postoperative clinical variables were examined.Univariate and multivariate logistic regression analyses were conducted to identify independent factors associated with GG upgrading.Patients in GG upgraded group had higher total prostatespecific antigen(tPSA;median:14.43 ng ml^(−1) vs 10.52 ng ml^(−1),P=0.001)and PSA density(PSAD;median:0.45 ng ml^(−2) vs 0.27 ng ml^(−2),P<0.001)than those in GG nonupgraded group.Patients in upgraded group had a higher ratio for Prostate ImagingReporting and Data System(PI-RADS)score>3(86.4%vs 67.9%,P<0.001).Those with GG 1 in biopsy were more likely to experience GG upgrading after RP than those with GG 2(71 vs 54,P=0.016).Independent preoperative factors predicting GG upgrading were PI-RADS score>3(odds ratio[OR]:2.471,95%confidence interval[CI]:1.132–5.393;P=0.023),higher PSAD(P=0.001),and GG in biopsy(OR:0.241,95%CI:0.123–0.471;P<0.001).The histopathological analyses of RP specimens revealed that perineural invasion(PNI;OR:1.839,95%CI:1.027–3.490;P=0.041)was identified as an independent factor associated with GG upgrading.Our results revealed that GG in the biopsy,PSAD,PI-RADS score>3,and PNI were independent factors of GG upgrading.These factors should be considered for patients with ISUP grade≤2 PCa.展开更多
The Gleason grade group(GG)is an important basis for assessing the malignancy of prostate can-cer,but it requires invasive biopsy to obtain pathology.To noninvasively evaluate GG,an automatic prediction method is prop...The Gleason grade group(GG)is an important basis for assessing the malignancy of prostate can-cer,but it requires invasive biopsy to obtain pathology.To noninvasively evaluate GG,an automatic prediction method is proposed based on multi-scale convolutional neural network of the ensemble attention module trained with curriculum learning.First,a lesion-attention map based on the image of the region of interest is proposed in combination with the bottleneck attention module to make the network more focus on the lesion area.Second,the feature pyramid network is combined to make the network better learn the multi-scale information of the lesion area.Finally,in the network training,a curriculum based on the consistency gap between the visual evaluation and the pathological grade is proposed,which further improves the prediction performance of the network.Ex-perimental results show that the proposed method is better than the traditional network model in predicting GG performance.The quadratic weighted Kappa is 0.4711 and the positive predictive value for predicting clinically significant cancer is 0.9369.展开更多
Utilising dissolved gases analysis, a new insulation fault diagnosis methodfor power transformers is proposed. This method is based on the group grey relational grade analysismethod. First, according to the fault type...Utilising dissolved gases analysis, a new insulation fault diagnosis methodfor power transformers is proposed. This method is based on the group grey relational grade analysismethod. First, according to the fault type and grey reference sequence structure, some typicalfault samples are divided into several sets of grey reference sequences. These sets are structuredas one grey reference sequence group. Secondly, according to a new calculation method of the greyrelational coefficient, the individual relational coefficient and grade are computed. Then accordingto the given calculation method for the group grey relation grade, the group grey relational gradeis computed and the group grey relational grade matrix is structured. Finally, according to therelational sequence, the insulation fault is identified for power transformers. The results of alarge quantity of instant analyses show that the proposed method has higher diagnosis accuracy andreliability than the three-ratio method and the traditional grey relational method. It has goodclassified diagnosis ability and reliability.展开更多
Let G be a group, HG and R a G graded ring. We study the duality Theorem for G actions and smash products R#G/H of the G graded ring R and the G set G/H.
The classification of extended affine Lie algebras of type A 1 depends on the Tits-Kantor-Koecher (TKK) algebras constructed from semilattices of Euclidean spaces. One can define a unitary Jordan algebra J(S) from a s...The classification of extended affine Lie algebras of type A 1 depends on the Tits-Kantor-Koecher (TKK) algebras constructed from semilattices of Euclidean spaces. One can define a unitary Jordan algebra J(S) from a semilattice S of ?v (v ≥ 1), and then construct an extended affine Lie algebra of type A 1 from the TKK algebra T(J(S)) which is obtained from the Jordan algebra J(S) by the so-called Tits-Kantor-Koecher construction. In ?2 there are only two non-similar semilattices S and S’, where S is a lattice and S’ is a non-lattice semilattice. In this paper we study the ?2-graded automorphisms of the TKK algebra T(J(S)).展开更多
Every extended affine Lie algebra of type A1 and nullity v with extended affine root system R（A1, S）, where S is a semilattice in Rv, can be constructed from a TKK Lie algebra T（J（S）） which is obtained from the ...Every extended affine Lie algebra of type A1 and nullity v with extended affine root system R（A1, S）, where S is a semilattice in Rv, can be constructed from a TKK Lie algebra T（J（S）） which is obtained from the Jordan algebra ,：7（S） by the so-called Tits-Kantor-Koecher construction. In this article we consider the Zn-graded automorphism group of the TKK Lie algebra T（J（S））, where S is the ＂smallest＂ semilattice in Euclidean space Rn.展开更多
Let n ≠ 0, 1 be an integer and Bn be the variety of n-Bell groups defined by the law [ xn, y] [ x, yn ] ^-1= 1. Let Bn be the class of groups in which for any infinite subsets X and Y there exist x ∈ X and y ∈ Y ...Let n ≠ 0, 1 be an integer and Bn be the variety of n-Bell groups defined by the law [ xn, y] [ x, yn ] ^-1= 1. Let Bn be the class of groups in which for any infinite subsets X and Y there exist x ∈ X and y ∈ Y such that [xn,y][x,yn]-1 = 1. In this paper we prove Bn ∩ L： = （Bn U F） M ∩L：, where F and L are the classes of all finite groups and all locally graded groups, respectively.展开更多
In this paper, we introduce the notation of graded FS-module of the graded module over a group G-graded ring and obtain some characterization involving graded maximal graded left ideal for a graded FS-ring and some e...In this paper, we introduce the notation of graded FS-module of the graded module over a group G-graded ring and obtain some characterization involving graded maximal graded left ideal for a graded FS-ring and some equivalent conditions between the ring R and group ring RG, the graded ring R and group ring of graded ring R[G].展开更多
Let D be a tame central division algebra over a Henselian valued field E,D be the residue division algebra of D,E be the residue field of E,and n be a positive integer.We prove that M_(n)(D)has a strictly maximal subf...Let D be a tame central division algebra over a Henselian valued field E,D be the residue division algebra of D,E be the residue field of E,and n be a positive integer.We prove that M_(n)(D)has a strictly maximal subfield which is Galois(resp.,abelian)over E if and only if M_(n)(D)has a strictly maximal subfield K which is Galois(resp.,abelian)and tame over E withГ_(K)■Г_(D),whereГ_(K)andГ_(D)are the value groups of K and D,respectively.This partially generalizes the result proved by Hanke et al.in 2016 for the case n=1.展开更多
Let G be a finite p-solvable group and k be an algebraic closed field of characteristic p. It is proved that any projective indecomposable module of a G-graded k-algebra is an induced module of a module of the subalge...Let G be a finite p-solvable group and k be an algebraic closed field of characteristic p. It is proved that any projective indecomposable module of a G-graded k-algebra is an induced module of a module of the subalgebra graded by a Hall p′-subgroup. A necessary and sufficient condition for the indecomposability of an induced module from a Hall p′-subgroup is obtained.展开更多
文摘We performed this study to investigate pathological upgrading from biopsy to prostatectomy and clinicopathological factors associated with grade group(GG)upgrading in patients with International Society of Urological Pathology(ISUP)GG 1 and 2 prostate cancer(PCa)in a Chinese cohort.We included patients diagnosed with PCa with ISUP GG 1 and 2 at biopsy,who underwent RP at our institution.Pre-and postoperative clinical variables were examined.Univariate and multivariate logistic regression analyses were conducted to identify independent factors associated with GG upgrading.Patients in GG upgraded group had higher total prostatespecific antigen(tPSA;median:14.43 ng ml^(−1) vs 10.52 ng ml^(−1),P=0.001)and PSA density(PSAD;median:0.45 ng ml^(−2) vs 0.27 ng ml^(−2),P<0.001)than those in GG nonupgraded group.Patients in upgraded group had a higher ratio for Prostate ImagingReporting and Data System(PI-RADS)score>3(86.4%vs 67.9%,P<0.001).Those with GG 1 in biopsy were more likely to experience GG upgrading after RP than those with GG 2(71 vs 54,P=0.016).Independent preoperative factors predicting GG upgrading were PI-RADS score>3(odds ratio[OR]:2.471,95%confidence interval[CI]:1.132–5.393;P=0.023),higher PSAD(P=0.001),and GG in biopsy(OR:0.241,95%CI:0.123–0.471;P<0.001).The histopathological analyses of RP specimens revealed that perineural invasion(PNI;OR:1.839,95%CI:1.027–3.490;P=0.041)was identified as an independent factor associated with GG upgrading.Our results revealed that GG in the biopsy,PSAD,PI-RADS score>3,and PNI were independent factors of GG upgrading.These factors should be considered for patients with ISUP grade≤2 PCa.
基金Foundation item:the Suzhou Municipal Health and Family Planning Commission's Key Diseases Diagnosis and Treatment Program(No.LCzX202001)the Science and Technology Development Project ofSuzhou(Nos.SS2019012andSKY2021031)+1 种基金the Youth Innovation Promotion Association CAS(No.2021324)the Medical Research Project of Jiangsu Provincial Health and Family Planning Commission(No.M2020068)。
文摘The Gleason grade group(GG)is an important basis for assessing the malignancy of prostate can-cer,but it requires invasive biopsy to obtain pathology.To noninvasively evaluate GG,an automatic prediction method is proposed based on multi-scale convolutional neural network of the ensemble attention module trained with curriculum learning.First,a lesion-attention map based on the image of the region of interest is proposed in combination with the bottleneck attention module to make the network more focus on the lesion area.Second,the feature pyramid network is combined to make the network better learn the multi-scale information of the lesion area.Finally,in the network training,a curriculum based on the consistency gap between the visual evaluation and the pathological grade is proposed,which further improves the prediction performance of the network.Ex-perimental results show that the proposed method is better than the traditional network model in predicting GG performance.The quadratic weighted Kappa is 0.4711 and the positive predictive value for predicting clinically significant cancer is 0.9369.
文摘Utilising dissolved gases analysis, a new insulation fault diagnosis methodfor power transformers is proposed. This method is based on the group grey relational grade analysismethod. First, according to the fault type and grey reference sequence structure, some typicalfault samples are divided into several sets of grey reference sequences. These sets are structuredas one grey reference sequence group. Secondly, according to a new calculation method of the greyrelational coefficient, the individual relational coefficient and grade are computed. Then accordingto the given calculation method for the group grey relation grade, the group grey relational gradeis computed and the group grey relational grade matrix is structured. Finally, according to therelational sequence, the insulation fault is identified for power transformers. The results of alarge quantity of instant analyses show that the proposed method has higher diagnosis accuracy andreliability than the three-ratio method and the traditional grey relational method. It has goodclassified diagnosis ability and reliability.
文摘Let G be a group, HG and R a G graded ring. We study the duality Theorem for G actions and smash products R#G/H of the G graded ring R and the G set G/H.
基金the National Natural Science Foundation of China (Grant No.10671160)
文摘The classification of extended affine Lie algebras of type A 1 depends on the Tits-Kantor-Koecher (TKK) algebras constructed from semilattices of Euclidean spaces. One can define a unitary Jordan algebra J(S) from a semilattice S of ?v (v ≥ 1), and then construct an extended affine Lie algebra of type A 1 from the TKK algebra T(J(S)) which is obtained from the Jordan algebra J(S) by the so-called Tits-Kantor-Koecher construction. In ?2 there are only two non-similar semilattices S and S’, where S is a lattice and S’ is a non-lattice semilattice. In this paper we study the ?2-graded automorphisms of the TKK algebra T(J(S)).
基金Supported by National Natural Science Foundation of China （Grant No. 10931006） and Foundation of Educational Department of Hubei Province in China （Grant No. B200529001） The author is grateful to the referee for some helpful suggestions.
文摘Every extended affine Lie algebra of type A1 and nullity v with extended affine root system R（A1, S）, where S is a semilattice in Rv, can be constructed from a TKK Lie algebra T（J（S）） which is obtained from the Jordan algebra ,：7（S） by the so-called Tits-Kantor-Koecher construction. In this article we consider the Zn-graded automorphism group of the TKK Lie algebra T（J（S））, where S is the ＂smallest＂ semilattice in Euclidean space Rn.
文摘Let n ≠ 0, 1 be an integer and Bn be the variety of n-Bell groups defined by the law [ xn, y] [ x, yn ] ^-1= 1. Let Bn be the class of groups in which for any infinite subsets X and Y there exist x ∈ X and y ∈ Y such that [xn,y][x,yn]-1 = 1. In this paper we prove Bn ∩ L： = （Bn U F） M ∩L：, where F and L are the classes of all finite groups and all locally graded groups, respectively.
文摘In this paper, we introduce the notation of graded FS-module of the graded module over a group G-graded ring and obtain some characterization involving graded maximal graded left ideal for a graded FS-ring and some equivalent conditions between the ring R and group ring RG, the graded ring R and group ring of graded ring R[G].
文摘Let D be a tame central division algebra over a Henselian valued field E,D be the residue division algebra of D,E be the residue field of E,and n be a positive integer.We prove that M_(n)(D)has a strictly maximal subfield which is Galois(resp.,abelian)over E if and only if M_(n)(D)has a strictly maximal subfield K which is Galois(resp.,abelian)and tame over E withГ_(K)■Г_(D),whereГ_(K)andГ_(D)are the value groups of K and D,respectively.This partially generalizes the result proved by Hanke et al.in 2016 for the case n=1.
文摘Let G be a finite p-solvable group and k be an algebraic closed field of characteristic p. It is proved that any projective indecomposable module of a G-graded k-algebra is an induced module of a module of the subalgebra graded by a Hall p′-subgroup. A necessary and sufficient condition for the indecomposability of an induced module from a Hall p′-subgroup is obtained.
