Introduction:We aimed to compare the oncological and functional outcomes of glansectomy and split-thickness skin graft reconstruction(GR)with those of glansectomy alone(GA)and penile amputation(PA).Materials and Metho...Introduction:We aimed to compare the oncological and functional outcomes of glansectomy and split-thickness skin graft reconstruction(GR)with those of glansectomy alone(GA)and penile amputation(PA).Materials and Methods:This retrospective study included patients with penile carcinoma or penile intraepithelial neoplasia diagnosed between 2017 and 2022.Surgical outcomes,complications,and oncological outcomes were assessed through a chart review,and functional outcomes were assessed using a questionnaire administered to patients who underwent GR(group A),GA(group B),or PA(group C).Results:Six,eight,and seven patients were enrolled in groups A,B,and C,respectively.Their complication rates were 0%,25%,and 29%,respectively;margin positivity rates were 17%,13%,and 0%,respectively;and local recurrence rates were 0%,0%,and 14%,respectively.Logistic regression analysis showed that being in group Arather than C was a significant predictor of favorable erectile function(p=0.007)and cosmetic outcomes(p=0.030).However,being in group A rather than B was not a significant predictor of favorable erectile function(p=0.127)or cosmetic outcomes(p=0.638).Conclusion:Excellent functional results were observed after GR;however,the benefits were significant only when compared with those of amputation.展开更多
Objective:Penile cancer(PeCa)is a rare disease with a global incidence of 36068 new cases in 2020.This accounts for 0.4%of all male malignancies.The surgical management of PeCa depends on the location of the tumour an...Objective:Penile cancer(PeCa)is a rare disease with a global incidence of 36068 new cases in 2020.This accounts for 0.4%of all male malignancies.The surgical management of PeCa depends on the location of the tumour and depth of invasion.Here,we review the oncological and functional outcomes of penile-preserving surgery(PPS).Methods:A PubMed search until July 2021 on PPS for PeCa was conducted;a narrative review on different penile-sparing approaches and outcomes was performed.Results:PPS is now the standard of care in specialist centres for distal tumours not involving the corpus cavernosa.Laser therapy,glans resurfacing,and wide local excision are options for superficial lesions,whilst glansectomy is required for lesions invading into the corpus spongiosum.Conclusion:PPS aims to preserve urinary and sexual function without compromising oncological outcomes.展开更多
文摘Introduction:We aimed to compare the oncological and functional outcomes of glansectomy and split-thickness skin graft reconstruction(GR)with those of glansectomy alone(GA)and penile amputation(PA).Materials and Methods:This retrospective study included patients with penile carcinoma or penile intraepithelial neoplasia diagnosed between 2017 and 2022.Surgical outcomes,complications,and oncological outcomes were assessed through a chart review,and functional outcomes were assessed using a questionnaire administered to patients who underwent GR(group A),GA(group B),or PA(group C).Results:Six,eight,and seven patients were enrolled in groups A,B,and C,respectively.Their complication rates were 0%,25%,and 29%,respectively;margin positivity rates were 17%,13%,and 0%,respectively;and local recurrence rates were 0%,0%,and 14%,respectively.Logistic regression analysis showed that being in group Arather than C was a significant predictor of favorable erectile function(p=0.007)and cosmetic outcomes(p=0.030).However,being in group A rather than B was not a significant predictor of favorable erectile function(p=0.127)or cosmetic outcomes(p=0.638).Conclusion:Excellent functional results were observed after GR;however,the benefits were significant only when compared with those of amputation.
文摘Objective:Penile cancer(PeCa)is a rare disease with a global incidence of 36068 new cases in 2020.This accounts for 0.4%of all male malignancies.The surgical management of PeCa depends on the location of the tumour and depth of invasion.Here,we review the oncological and functional outcomes of penile-preserving surgery(PPS).Methods:A PubMed search until July 2021 on PPS for PeCa was conducted;a narrative review on different penile-sparing approaches and outcomes was performed.Results:PPS is now the standard of care in specialist centres for distal tumours not involving the corpus cavernosa.Laser therapy,glans resurfacing,and wide local excision are options for superficial lesions,whilst glansectomy is required for lesions invading into the corpus spongiosum.Conclusion:PPS aims to preserve urinary and sexual function without compromising oncological outcomes.
