Present day power scenarios demand a high quality uninterrupted power supply and needs environmental issues to be addressed. Both concerns can be dealt with by the introduction of the renewable sources to the existing...Present day power scenarios demand a high quality uninterrupted power supply and needs environmental issues to be addressed. Both concerns can be dealt with by the introduction of the renewable sources to the existing power system. Thus, automatic generation control(AGC) with diverse renewable sources and a modified-cascaded controller are presented in the paper.Also, a new hybrid scheme of the improved teaching learning based optimization-differential evolution(hITLBO-DE) algorithm is applied for providing optimization of controller parameters. A study of the system with a technique such as TLBO applied to a proportional integral derivative(PID), integral double derivative(IDD) and PIDD is compared to hITLBO-DE tuned cascaded controller with dynamic load change.The suggested methodology has been extensively applied to a 2-area system with a diverse source power system with various operation time non-linearities such as dead-band of, generation rate constraint and reheat thermal units. The multi-area system with reheat thermal plants, hydel plants and a unit of a wind-diesel combination is tested with the cascaded controller scheme with a different controller setting for each area. The variation of the load is taken within 1% to 5% of the connected load and robustness analysis is shown by modifying essential factors simultaneously by± 30%. Finally, the proposed scheme of controller and optimization technique is also tested with a 5-equal area thermal system with non-linearities. The simulation results demonstrate the superiority of the proposed controller and algorithm under a dynamically changing load.展开更多
As the hydrocarbon generation and storage mechanisms of high quality shales of Upper Ordovician Wufeng Formation– Lower Silurian Longmaxi Formation remain unclear, based on geological conditions and experimental mode...As the hydrocarbon generation and storage mechanisms of high quality shales of Upper Ordovician Wufeng Formation– Lower Silurian Longmaxi Formation remain unclear, based on geological conditions and experimental modelling of shale gas formation, the shale gas generation and accumulation mechanisms as well as their coupling relationships of deep-water shelf shales in Wufeng–Longmaxi Formation of Sichuan Basin were analyzed from petrology, mineralogy, and geochemistry. The high quality shales of Wufeng–Longmaxi Formation in Sichuan Basin are characterized by high thermal evolution, high hydrocarbon generation intensity, good material base, and good roof and floor conditions;the high quality deep-water shelf shale not only has high biogenic silicon content and organic carbon content, but also high porosity coupling. It is concluded that:(1) The shales had good preservation conditions and high retainment of crude oil in the early times, and the shale gas was mainly from cracking of crude oil.(2) The biogenic silicon(opal A) turned into crystal quartz in early times of burial diagenesis, lots of micro-size intergranular pores were produced in the same time;moreover, the biogenic silicon frame had high resistance to compaction, thus it provided the conditions not only for oil charge in the early stage, but also for formation and preservation of nanometer cellular-like pores, and was the key factor enabling the preservation of organic pores.(3) The high quality shale of Wufeng–Longmaxi Formation had high brittleness, strong homogeneity, siliceous intergranular micro-pores and nanometer organic pores, which were conducive to the formation of complicated fissure network connecting the siliceous intergranular nano-pores, and thus high and stable production of shale gas.展开更多
1 Introduction The growing connectivity with mobile internet has significantly enhanced our day-to-day life support through various services and applications with on-demand availability at any time or anywhere.As emer...1 Introduction The growing connectivity with mobile internet has significantly enhanced our day-to-day life support through various services and applications with on-demand availability at any time or anywhere.As emerging technologies with continuous revolutions in the digital transformations,various add-on technologies such as quantum computing,AI,and next-generation networks such as 6G are becoming an integral support to mobile internet systems.The emerging technologies in the next-generation mobile internet bring a lot of new security and privacy challenges.展开更多
Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.You...Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.Young students,with their active and vibrant minds,represent the future and hope of standardization.展开更多
Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment.Nocardia cyriacigeorgica(N.cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,^([1]) and...Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment.Nocardia cyriacigeorgica(N.cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,^([1]) and has since been reported as an emerging clinically relevant pathogen worldwide.The diagnosis of nocardial infections remains challenging due to nonspecific symptoms and low culture sensitivity,resulting in high mortality.^([2]) Herein,we report a case of N.cyriacigeorgica brain abscess in an immunosuppressed patient who was successfully treated with antibiotics and surgery.展开更多
Next-generation craniomaxillofacial implants(CMFIs) are redefining personalized bone reconstruction by balancing and optimizing biomechanics,biocompatibility,and bioactivity—the "3Bs".This review highlights...Next-generation craniomaxillofacial implants(CMFIs) are redefining personalized bone reconstruction by balancing and optimizing biomechanics,biocompatibility,and bioactivity—the "3Bs".This review highlights recent progress in implant design,material development,additive manufacturing,and preclinical evaluation.Emerging biomaterials,including bioresorbable polymers,magnesium alloys,and composites with bioactive ceramics,enable patient-specific solutions with improved safety and functionality.Triply periodic minimal surface(TPMS) architectures exemplify how structural design can enhance both mechanical performance and biological integration.Additive manufacturing technologies further allow the fabrication of geometrically complex,customized impla nts that meet individual anatomical and pathological needs.In parallel,multiscale evaluation techniques—from mechanical testing to in vitro and in vivo models—provide comprehensive insights into implant performance and safety.Looking ahead,the field is poised to benefit from several transformative trends:the development of smart and multifunctional biomaterials;Al-driven design frameworks that leverage patient-specific data and computational modeling;predictive additive manufacturing with real-time quality control;and advanced biological testing platforms for preclinical evaluation.Together,these advances form the foundation of a data-informed,translational pipeline from bench to bedside.Realizing the full potential of nextgene ration CMFIs will require close interdisciplina ry collaboration across mate rials science,computational engineering,and clinical medicine.展开更多
Hydrogel microcapsules are powerful microreactor vessels that have attracted widespread attention and research.Among the various methods for their generation,the aqueous two-phase system(ATPS)is by far the most straig...Hydrogel microcapsules are powerful microreactor vessels that have attracted widespread attention and research.Among the various methods for their generation,the aqueous two-phase system(ATPS)is by far the most straightforward approach.However,the high viscosity of ATPS solutions significantly limits the generation throughput of hydrogel microcapsule.In this study,we developed a novel high-throughput approach for generating hydrogel microcapsules using a microfluidic bubble-triggering strategy.By integrating constant-pressure air flow with droplet microfluidics devices,we efficiently manipulated the formation of ATPS droplet through bubble-induced Rayleigh-Plateau instability,enabling the production of uniform,monodisperse microcapsules.Additionally,the droplet generation frequency in the bubble-triggering method exceeded 36 kHz.We further demonstrated the encapsulation of genetically engineered Escherichia coli strains,which acted as biosensors for arsenic ions and caprolactam,highlighting the potential of these microcapsules for biosensing applications.This advancement in hydrogel microcapsule generation offers promising implications for scalable applications in biosensing,organoid culture,and high-throughput screening.展开更多
Dear Editor,This letter presents techniques to simplify dataset generation for instance segmentation of raw meat products,a critical step toward automating food production lines.Accurate segmentation is essential for ...Dear Editor,This letter presents techniques to simplify dataset generation for instance segmentation of raw meat products,a critical step toward automating food production lines.Accurate segmentation is essential for addressing challenges such as occlusions,indistinct edges,and stacked configurations,which demand large,diverse datasets.To meet these demands,we propose two complementary approaches:a semi-automatic annotation interface using tools like the segment anything model(SAM)and GrabCut and a synthetic data generation pipeline leveraging 3D-scanned models.These methods reduce reliance on real meat,mitigate food waste,and improve scalability.Experimental results demonstrate that incorporating synthetic data enhances segmentation model performance and,when combined with real data,further boosts accuracy,paving the way for more efficient automation in the food industry.展开更多
Hydraulic stimulation technology is widely employed to enhance the permeability of geothermal reservoirs.Nevertheless,accurately predicting hydraulic fracture propagation in complex geological conditions remains chall...Hydraulic stimulation technology is widely employed to enhance the permeability of geothermal reservoirs.Nevertheless,accurately predicting hydraulic fracture propagation in complex geological conditions remains challenging,thereby hindering the effective utilization of existing natural fractures.In this study,a phase field model was developed utilizing the finite element method to examine the influence of fluid presence,stress conditions,and natural fractures on the initiation and propagation of hydraulic fractures.The model employs Biot's poroelasticity theory to establish the coupling between the displacement field and the fluid field,while the phase field theory is applied to simulate fracture behavior.The results show that whenσ_(x0)/σ_(y0)<3 or qf<20 kg/(m^(3)·s),the presence of natural fractures can alter the original propagation direction of hydraulic fractures.Conversely,in the absence of these conditions,the propagation path of natural fractures is predominantly influenced by the initial stress field.Furthermore,based on the analysis of breakdown pressure and damage area,the optimal intersection angle between natural fractures and hydraulic fractures is determined to range from 45°to 60°.Finally,once a dominant channel forms,initiating and propagating hydraulic fractures in other directions becomes increasingly difficult,even in highly fractured areas.This method tackles the challenges of initiating and propagating hydraulic fractures in complex geological conditions,providing a theoretical basis for optimizing Enhanced Geothermal System(EGS)projects.展开更多
The kinetic parameters of hydrocarbon generation are determined through experimental simulation and mathematical calculation using four typical samples selected from the Cretaceous Nenjiang Formation in the northwest ...The kinetic parameters of hydrocarbon generation are determined through experimental simulation and mathematical calculation using four typical samples selected from the Cretaceous Nenjiang Formation in the northwest of Songliao Basin,Chang 7 Member of Triassic Yanchang Formation in the southwest of Ordos Basin,Paleogene in the southwest of Qaidam Basin,and Lucaogou Formation of Jimusar Sag in the east of Junggar Basin.The results show that activation energy of hydrocarbon generation of organic matter is closely related to maturity and mainly ranges between 197 kJ/mol and 227 kJ/mol.On this basis,the temperature required for organic matter in shale to convert into oil was calculated.The ideal heating temperature is between 270℃and 300℃,and the conversation rate can reach 90%after 50-300 days of heating at constant temperature.When the temperature rises at a constant rate,the temperature corresponding to the major hydrocarbon generation period ranges from 225 to 350℃at the temperature rise rate of 1-150℃/month.In order to obtain higher economic benefits,it is suggested to adopt higher temperature rise rate(60-150℃/month).The more reliable kinetic parameters obtained can provide a basis for designing more reasonable scheme of in-situ heating conversion.展开更多
The energy loss of the power grid is one of the key factors affecting the economic operation of power systems. How to calculate the electric energy consumption accurately will have a great influence on the planning, o...The energy loss of the power grid is one of the key factors affecting the economic operation of power systems. How to calculate the electric energy consumption accurately will have a great influence on the planning, operation and management of the power grid. Currently there is a mountain of theoretical methods to calculate the line loss of the power system. However, these methods have some limitation, such as less considering the volatility of wind power resources. This paper presents an improved method to calculate the energy loss of wind power generation, considering the fluctuations of wind power generation. First, data are collected to obtain the curve of the typical daily expected output of wind farms for one month. Second, the curve of the typical daily expected output are corrected by the average electricity and the shape factor to obtain the curve of the typical daily equivalent output of wind farms for one month. Finally, the power flow is calculated by using typical daily equivalent output curve to describe the energy loss for one month. The results in the 110 kV main network show that the method is feasible.展开更多
The rapid spreading of the Photovoltaic (PV) Systems as Distributed Generation (DG) in medium and low voltage networks created many effects and changes on the existing power system networks. In this work, two methods ...The rapid spreading of the Photovoltaic (PV) Systems as Distributed Generation (DG) in medium and low voltage networks created many effects and changes on the existing power system networks. In this work, two methods have been used and applied to determine the optimal allocation and sizing of the PV to be installed as DGs (ranging from 250 kW up to 3 MW). The first one is to determine the location according to the maximal power losses reduction over the feeder. The second one is by using the Harmony Search Algorithm which is claimed to be a powerful technique for optimal allocation of PV systems. The results of the two techniques were compared and found to be nearly closed. Furthermore, investigation on the effects on the feeder in terms of voltage levels, power factor readings, and short circuit current levels has been done. All calculations and simulations are conducted by using the MATLAB Simulation Program. Some field calculations and observations have been expended in order to substantiate the research findings and validation.展开更多
In this paper, a significant enhancement in current efficiency of the green tandem organic light-emitting diodes(TOLEDs) is demonstrated, which is based on a buffer-modified charge generation layer(CGL) of fullerene c...In this paper, a significant enhancement in current efficiency of the green tandem organic light-emitting diodes(TOLEDs) is demonstrated, which is based on a buffer-modified charge generation layer(CGL) of fullerene carbon(C60)/zinc-phthalocyanine(ZnPc). Al and MoO3 were used as the buffer-modified layers on both sides of the bilayer C60/ZnPc, respectively. Experimental results show that the inserted Al and MoO3 layers can effectively increase the electron extraction of the CGL for obtaining the device performance enhancement. Compared with that of the green TOLEDs without buffer-modified layers in CGL(37.3 cd·A-1), the current efficiency of the green TOLEDs is increased to 54.1 cd·A-1. Further study results find that the performance can also be improved by optimizing the thickness of Al in the CGL. The maximum current efficiency and maximum luminance of the green TOLEDs achieve 63.5 cd·A-1 and 17 873 cd·m-2, respectively, when the multilayer structure of the CGL is Al(3 nm)/C60(5 nm)/ZnPc(5 nm)/MoO3(3 nm).展开更多
Electroosmotic transport and entropy generation play a decisive role in regulating efficiency,stability,and energy cost of non-Newtonian nanoblood flows in stenosed arteries,particularly with tapered geometries.Thisst...Electroosmotic transport and entropy generation play a decisive role in regulating efficiency,stability,and energy cost of non-Newtonian nanoblood flows in stenosed arteries,particularly with tapered geometries.Thisstudy develops a unified model to analyze ZnO-Williamson nanoblood flow through a stenosed artery with converging,diverging,and non-tapered configurations,incorporating electroosmosis,viscous dissipation,and entropy production.The arterial walls are assumed to be electrically charged with a no-slip condition to induce electroosmotic propulsionalong the endothelial surface.The partial differential equations are nondimensionalized to a coupled system ofnonlinear ordinary differential equations,which are solved numerically using a MATLAB-based shooting technique.Parametric investigation is conducted for Brinkman,Grashof,and Weissenberg numbers,ZnO fractional volume,volumetric flow rate,and Helmholtz-Smoluchowski velocity to quantify their influences on axial velocity,wall shearstress,impedance resistance,temperature distribution,entropy generation,Bejan number,and streamline topology.The axial velocity decreases radially with increasing Brinkman number for all arterial geometries.Increasing ZnOnanoparticles improves thermal transport owing to enhanced effective thermal conductivity but simultaneously elevatesentropy generation due to increased viscous dissipation.Higher Weissenberg numbers suppress entropy production bypromoting elastic stress redistribution and lowering shear-induced irreversibility.Impedance resistance decreases withincreasing stenosis height but increases with stenosis shape parameter and ZnO fractional volume.Streamline analysisshows that buoyancy and viscoelasticity significantly distort flow near the stenosis,while increasing electroosmoticvelocity stabilizes streamlines,suppresses recirculation,and reduces local shear stress and pressure fluctuations.Inconclusion,electroosmotic actuation is most effective in reducing flow resistance in the converging tapered artery,particularly at lower ZnO volume fractions.Overall,the findings highlight the potential of optimized electroosmoticactuation and controlled nanoparticle loading to minimize thermodynamic losses,regulate shear stress,and improveflow uniformity in stenosed vessels,with promising implications for electro-assisted drug delivery,nanotherapeutics,and bio-inspired vascular microfluidic systems.展开更多
The occurrence of severe thalassemia,an inherited blood disorder that is either blood-transfusiondependent or fatal,can be mitigated through carrier screening.Here,we aim to evaluate the effectiveness and outcomes of ...The occurrence of severe thalassemia,an inherited blood disorder that is either blood-transfusiondependent or fatal,can be mitigated through carrier screening.Here,we aim to evaluate the effectiveness and outcomes of pre-conceptional and early pregnancy screening initiatives for severe thalassemia prevention in a diverse population of 28,043 women.Using next-generation sequencing(NGS),we identify 4,226(15.07%)thalassemia carriers across 29 ethnic groups and categorize them into high-(0.75%),low-(25.86%),and unknown-risk(69.19%)groups based on their spouses'screening results.Post-screening follow-up reveals 59 fetuses with severe thalassemia exclusively in high-risk couples,underscoring the efficacy of risk classification.Among 25,053 live births over 6 months of age,two severe thalassemia infants were born to unknown-risk couples,which was attributed to incomplete screening and late NGS-based testing for a rare variant.Notably,64 rare variants are identified in 287 individuals,highlighting the genetic heterogeneity of thalassemia.We also observe that migrant flow significantly impacts carrier rates,with 93.90%of migrants to Chenzhou originating from high-prevalence regions in southern China.Our study demonstrates that NGS-based screening during pre-conception and early pregnancy is effective for severe thalassemia prevention,emphasizing the need for continuous screening efforts in areas with high and underestimated prevalence.展开更多
We are sorry for the mistakes of Affiliation,"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,Donghua University,Shanghai 201620,China"should be replaced by&quo...We are sorry for the mistakes of Affiliation,"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,Donghua University,Shanghai 201620,China"should be replaced by"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,College of Materials Science and Engineering,Donghua University,Shanghai 201620,China".We apologized for the inconvenience caused by this error.展开更多
Due to the complex structural hierarchy,with deeply nested associative relations between entities such as equipment,specifications,and business processes,intelligent power grid engineering is challenging.Meanwhile,lim...Due to the complex structural hierarchy,with deeply nested associative relations between entities such as equipment,specifications,and business processes,intelligent power grid engineering is challenging.Meanwhile,limited by the fragmented data and loss of contextual information,the generated reports are prone to the problems such as content redundancy and omission of critical information,failing to meet the demands of efficient decision-making and accurate management in modern power systems.To address these issues,this paper proposes a knowledge graph(KG)-enhanced framework to automatically generate electric power engineering reports.In the KG construction phase,a feature-fused entity recognition model named BERT-BiLSTM-CRF is adopted to improve the accuracy of entity recognition in scenarios involving power engineering professional terminology,thereby solving the problem of ambiguous entity boundaries in traditional models;then a BERT-attention relation extraction model is proposed to enhance the completeness of extracting complex hierarchical and implicit relations in power grid data.In the report generation phase,an improved Transformer architecture is adopted to accurately transform structured knowledge into natural language reports that comply with engineering specifications,addressing the issue of semantic inconsistency caused by the loss of structural information in existing models.By validating with real-world projects,the results show that the proposed framework significantly outperforms existing baseline models in entity recognition,confirming its superiority and applicability in practical engineering.展开更多
In Human–Robot Interaction(HRI),generating robot trajectories that accurately reflect user intentions while ensuring physical realism remains challenging,especially in unstructured environments.In this study,we devel...In Human–Robot Interaction(HRI),generating robot trajectories that accurately reflect user intentions while ensuring physical realism remains challenging,especially in unstructured environments.In this study,we develop a multimodal framework that integrates symbolic task reasoning with continuous trajectory generation.The approach employs transformer models and adversarial training to map high-level intent to robotic motion.Information from multiple data sources,such as voice traits,hand and body keypoints,visual observations,and recorded paths,is integrated simultaneously.These signals are mapped into a shared representation that supports interpretable reasoning while enabling smooth and realistic motion generation.Based on this design,two different learning strategies are investigated.In the first step,grammar-constrained Linear Temporal Logic(LTL)expressions are created from multimodal human inputs.These expressions are subsequently decoded into robot trajectories.The second method generates trajectories directly from symbolic intent and linguistic data,bypassing an intermediate logical representation.Transformer encoders combine multiple types of information,and autoregressive transformer decoders generate motion sequences.Adding smoothness and speed limits during training increases the likelihood of physical feasibility.To improve the realism and stability of the generated trajectories during training,an adversarial discriminator is also included to guide them toward the distribution of actual robot motion.Tests on the NATSGLD dataset indicate that the complete system exhibits stable training behaviour and performance.In normalised coordinates,the logic-based pipeline has an Average Displacement Error(ADE)of 0.040 and a Final Displacement Error(FDE)of 0.036.The adversarial generator makes substantially more progress,reducing ADE to 0.021 and FDE to 0.018.Visual examination confirms that the generated trajectories closely align with observed motion patterns while preserving smooth temporal dynamics.展开更多
The power systems economic and safety operation considering large-scale wind power penetration are now facing great challenges, which are based on reliable power supply and predictable load demands in the past. A roll...The power systems economic and safety operation considering large-scale wind power penetration are now facing great challenges, which are based on reliable power supply and predictable load demands in the past. A rolling generation dispatch model based on ultra-short-term wind power forecast was proposed. In generation dispatch process, the model rolling correct not only the conventional units power output but also the power from wind farm, simultaneously. Second order Markov chain model was utilized to modify wind power prediction error state (WPPES) and update forecast results of wind power over the remaining dispatch periods. The prime-dual affine scaling interior point method was used to solve the proposed model that taken into account the constraints of multi-periods power balance, unit output adjustment, up spinning reserve and down spinning reserve.展开更多
A controllable strategy for eliciting nuclear fusion is presented through ultra-intenselaser derived positron generation by a conceptual first physics perspective. The capability to generate positrons on demand in a c...A controllable strategy for eliciting nuclear fusion is presented through ultra-intenselaser derived positron generation by a conceptual first physics perspective. The capability to generate positrons on demand in a controlled manner through an ultra-intense laser incident on a high atomic number target, such as gold, is the intrinsic core to the foundation of controllable nuclear fusion. Positron antimatter generated from the periphery of the fusion fuel pellet provides the basis for initiating the fusion reaction, which is regulated by controlling the operation of the ultra-intense laser. A dual pulsed Fast Ignition mechanism is selected to achieve the fusion reaction. Based on first physics performance analysis the controllable strategy for eliciting nuclear fusion through ultra-intenselaser derived positron generation offers a realizable means for achieving regulated nuclear fusion. A future perspective of the controllable fusion strategy addresses the opportunities and concerns of a pathway toward regulated nuclear fusion.展开更多
文摘Present day power scenarios demand a high quality uninterrupted power supply and needs environmental issues to be addressed. Both concerns can be dealt with by the introduction of the renewable sources to the existing power system. Thus, automatic generation control(AGC) with diverse renewable sources and a modified-cascaded controller are presented in the paper.Also, a new hybrid scheme of the improved teaching learning based optimization-differential evolution(hITLBO-DE) algorithm is applied for providing optimization of controller parameters. A study of the system with a technique such as TLBO applied to a proportional integral derivative(PID), integral double derivative(IDD) and PIDD is compared to hITLBO-DE tuned cascaded controller with dynamic load change.The suggested methodology has been extensively applied to a 2-area system with a diverse source power system with various operation time non-linearities such as dead-band of, generation rate constraint and reheat thermal units. The multi-area system with reheat thermal plants, hydel plants and a unit of a wind-diesel combination is tested with the cascaded controller scheme with a different controller setting for each area. The variation of the load is taken within 1% to 5% of the connected load and robustness analysis is shown by modifying essential factors simultaneously by± 30%. Finally, the proposed scheme of controller and optimization technique is also tested with a 5-equal area thermal system with non-linearities. The simulation results demonstrate the superiority of the proposed controller and algorithm under a dynamically changing load.
基金Supported by the China National Science and Technology Major Project(2017ZX05036,2017ZX05036001).
文摘As the hydrocarbon generation and storage mechanisms of high quality shales of Upper Ordovician Wufeng Formation– Lower Silurian Longmaxi Formation remain unclear, based on geological conditions and experimental modelling of shale gas formation, the shale gas generation and accumulation mechanisms as well as their coupling relationships of deep-water shelf shales in Wufeng–Longmaxi Formation of Sichuan Basin were analyzed from petrology, mineralogy, and geochemistry. The high quality shales of Wufeng–Longmaxi Formation in Sichuan Basin are characterized by high thermal evolution, high hydrocarbon generation intensity, good material base, and good roof and floor conditions;the high quality deep-water shelf shale not only has high biogenic silicon content and organic carbon content, but also high porosity coupling. It is concluded that:(1) The shales had good preservation conditions and high retainment of crude oil in the early times, and the shale gas was mainly from cracking of crude oil.(2) The biogenic silicon(opal A) turned into crystal quartz in early times of burial diagenesis, lots of micro-size intergranular pores were produced in the same time;moreover, the biogenic silicon frame had high resistance to compaction, thus it provided the conditions not only for oil charge in the early stage, but also for formation and preservation of nanometer cellular-like pores, and was the key factor enabling the preservation of organic pores.(3) The high quality shale of Wufeng–Longmaxi Formation had high brittleness, strong homogeneity, siliceous intergranular micro-pores and nanometer organic pores, which were conducive to the formation of complicated fissure network connecting the siliceous intergranular nano-pores, and thus high and stable production of shale gas.
文摘1 Introduction The growing connectivity with mobile internet has significantly enhanced our day-to-day life support through various services and applications with on-demand availability at any time or anywhere.As emerging technologies with continuous revolutions in the digital transformations,various add-on technologies such as quantum computing,AI,and next-generation networks such as 6G are becoming an integral support to mobile internet systems.The emerging technologies in the next-generation mobile internet bring a lot of new security and privacy challenges.
文摘Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.Young students,with their active and vibrant minds,represent the future and hope of standardization.
基金funded by grants from Guangdong Basic and Applied Basic Research Foundation (2025A1515011901)Natural Science Foundation of Guangdong Province (2024A1515012228)。
文摘Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment.Nocardia cyriacigeorgica(N.cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,^([1]) and has since been reported as an emerging clinically relevant pathogen worldwide.The diagnosis of nocardial infections remains challenging due to nonspecific symptoms and low culture sensitivity,resulting in high mortality.^([2]) Herein,we report a case of N.cyriacigeorgica brain abscess in an immunosuppressed patient who was successfully treated with antibiotics and surgery.
基金Financial support from National University of Singapore (NUS)(AcRF A-8000-126-00-00)。
文摘Next-generation craniomaxillofacial implants(CMFIs) are redefining personalized bone reconstruction by balancing and optimizing biomechanics,biocompatibility,and bioactivity—the "3Bs".This review highlights recent progress in implant design,material development,additive manufacturing,and preclinical evaluation.Emerging biomaterials,including bioresorbable polymers,magnesium alloys,and composites with bioactive ceramics,enable patient-specific solutions with improved safety and functionality.Triply periodic minimal surface(TPMS) architectures exemplify how structural design can enhance both mechanical performance and biological integration.Additive manufacturing technologies further allow the fabrication of geometrically complex,customized impla nts that meet individual anatomical and pathological needs.In parallel,multiscale evaluation techniques—from mechanical testing to in vitro and in vivo models—provide comprehensive insights into implant performance and safety.Looking ahead,the field is poised to benefit from several transformative trends:the development of smart and multifunctional biomaterials;Al-driven design frameworks that leverage patient-specific data and computational modeling;predictive additive manufacturing with real-time quality control;and advanced biological testing platforms for preclinical evaluation.Together,these advances form the foundation of a data-informed,translational pipeline from bench to bedside.Realizing the full potential of nextgene ration CMFIs will require close interdisciplina ry collaboration across mate rials science,computational engineering,and clinical medicine.
基金sponsored by the National Key R&D Program of China(no.2023YFB3208203)the National Natural Science Foundation of China(no.62374170)the Science and Technology Commission of Shanghai Municipality(no.23J21900200).
文摘Hydrogel microcapsules are powerful microreactor vessels that have attracted widespread attention and research.Among the various methods for their generation,the aqueous two-phase system(ATPS)is by far the most straightforward approach.However,the high viscosity of ATPS solutions significantly limits the generation throughput of hydrogel microcapsule.In this study,we developed a novel high-throughput approach for generating hydrogel microcapsules using a microfluidic bubble-triggering strategy.By integrating constant-pressure air flow with droplet microfluidics devices,we efficiently manipulated the formation of ATPS droplet through bubble-induced Rayleigh-Plateau instability,enabling the production of uniform,monodisperse microcapsules.Additionally,the droplet generation frequency in the bubble-triggering method exceeded 36 kHz.We further demonstrated the encapsulation of genetically engineered Escherichia coli strains,which acted as biosensors for arsenic ions and caprolactam,highlighting the potential of these microcapsules for biosensing applications.This advancement in hydrogel microcapsule generation offers promising implications for scalable applications in biosensing,organoid culture,and high-throughput screening.
基金supported by European Union’s Horizon Europe research and innovation programme,project AGILEHAND(Smart Grading,Handling and Packaging Solutions for Soft and Deformable Products in Agile and Reconfigurable Lines)(101092043).
文摘Dear Editor,This letter presents techniques to simplify dataset generation for instance segmentation of raw meat products,a critical step toward automating food production lines.Accurate segmentation is essential for addressing challenges such as occlusions,indistinct edges,and stacked configurations,which demand large,diverse datasets.To meet these demands,we propose two complementary approaches:a semi-automatic annotation interface using tools like the segment anything model(SAM)and GrabCut and a synthetic data generation pipeline leveraging 3D-scanned models.These methods reduce reliance on real meat,mitigate food waste,and improve scalability.Experimental results demonstrate that incorporating synthetic data enhances segmentation model performance and,when combined with real data,further boosts accuracy,paving the way for more efficient automation in the food industry.
基金supported by the National Key Research and Development Program(2021YFB150740401)National Natural Science Foundation of China(42202336)the CAS Pioneer Hundred Talents Program in China(Y826031C01)。
文摘Hydraulic stimulation technology is widely employed to enhance the permeability of geothermal reservoirs.Nevertheless,accurately predicting hydraulic fracture propagation in complex geological conditions remains challenging,thereby hindering the effective utilization of existing natural fractures.In this study,a phase field model was developed utilizing the finite element method to examine the influence of fluid presence,stress conditions,and natural fractures on the initiation and propagation of hydraulic fractures.The model employs Biot's poroelasticity theory to establish the coupling between the displacement field and the fluid field,while the phase field theory is applied to simulate fracture behavior.The results show that whenσ_(x0)/σ_(y0)<3 or qf<20 kg/(m^(3)·s),the presence of natural fractures can alter the original propagation direction of hydraulic fractures.Conversely,in the absence of these conditions,the propagation path of natural fractures is predominantly influenced by the initial stress field.Furthermore,based on the analysis of breakdown pressure and damage area,the optimal intersection angle between natural fractures and hydraulic fractures is determined to range from 45°to 60°.Finally,once a dominant channel forms,initiating and propagating hydraulic fractures in other directions becomes increasingly difficult,even in highly fractured areas.This method tackles the challenges of initiating and propagating hydraulic fractures in complex geological conditions,providing a theoretical basis for optimizing Enhanced Geothermal System(EGS)projects.
基金Supported by the PetroChina Science and Technology Major Project(2016E-0101).
文摘The kinetic parameters of hydrocarbon generation are determined through experimental simulation and mathematical calculation using four typical samples selected from the Cretaceous Nenjiang Formation in the northwest of Songliao Basin,Chang 7 Member of Triassic Yanchang Formation in the southwest of Ordos Basin,Paleogene in the southwest of Qaidam Basin,and Lucaogou Formation of Jimusar Sag in the east of Junggar Basin.The results show that activation energy of hydrocarbon generation of organic matter is closely related to maturity and mainly ranges between 197 kJ/mol and 227 kJ/mol.On this basis,the temperature required for organic matter in shale to convert into oil was calculated.The ideal heating temperature is between 270℃and 300℃,and the conversation rate can reach 90%after 50-300 days of heating at constant temperature.When the temperature rises at a constant rate,the temperature corresponding to the major hydrocarbon generation period ranges from 225 to 350℃at the temperature rise rate of 1-150℃/month.In order to obtain higher economic benefits,it is suggested to adopt higher temperature rise rate(60-150℃/month).The more reliable kinetic parameters obtained can provide a basis for designing more reasonable scheme of in-situ heating conversion.
文摘The energy loss of the power grid is one of the key factors affecting the economic operation of power systems. How to calculate the electric energy consumption accurately will have a great influence on the planning, operation and management of the power grid. Currently there is a mountain of theoretical methods to calculate the line loss of the power system. However, these methods have some limitation, such as less considering the volatility of wind power resources. This paper presents an improved method to calculate the energy loss of wind power generation, considering the fluctuations of wind power generation. First, data are collected to obtain the curve of the typical daily expected output of wind farms for one month. Second, the curve of the typical daily expected output are corrected by the average electricity and the shape factor to obtain the curve of the typical daily equivalent output of wind farms for one month. Finally, the power flow is calculated by using typical daily equivalent output curve to describe the energy loss for one month. The results in the 110 kV main network show that the method is feasible.
文摘The rapid spreading of the Photovoltaic (PV) Systems as Distributed Generation (DG) in medium and low voltage networks created many effects and changes on the existing power system networks. In this work, two methods have been used and applied to determine the optimal allocation and sizing of the PV to be installed as DGs (ranging from 250 kW up to 3 MW). The first one is to determine the location according to the maximal power losses reduction over the feeder. The second one is by using the Harmony Search Algorithm which is claimed to be a powerful technique for optimal allocation of PV systems. The results of the two techniques were compared and found to be nearly closed. Furthermore, investigation on the effects on the feeder in terms of voltage levels, power factor readings, and short circuit current levels has been done. All calculations and simulations are conducted by using the MATLAB Simulation Program. Some field calculations and observations have been expended in order to substantiate the research findings and validation.
基金supported by the Scientific and Technological Research Foundation of Chongqing Municipal Education Commission(No.KJ1600439)the Basic and Advanced Technology Research Project of Chongqing Municipality(No.cstc2018jcyjAX0462)the Scientific and Technological Research Foundation of Chongqing Municipal Education Commission(No.KJ1500404)
文摘In this paper, a significant enhancement in current efficiency of the green tandem organic light-emitting diodes(TOLEDs) is demonstrated, which is based on a buffer-modified charge generation layer(CGL) of fullerene carbon(C60)/zinc-phthalocyanine(ZnPc). Al and MoO3 were used as the buffer-modified layers on both sides of the bilayer C60/ZnPc, respectively. Experimental results show that the inserted Al and MoO3 layers can effectively increase the electron extraction of the CGL for obtaining the device performance enhancement. Compared with that of the green TOLEDs without buffer-modified layers in CGL(37.3 cd·A-1), the current efficiency of the green TOLEDs is increased to 54.1 cd·A-1. Further study results find that the performance can also be improved by optimizing the thickness of Al in the CGL. The maximum current efficiency and maximum luminance of the green TOLEDs achieve 63.5 cd·A-1 and 17 873 cd·m-2, respectively, when the multilayer structure of the CGL is Al(3 nm)/C60(5 nm)/ZnPc(5 nm)/MoO3(3 nm).
基金funded by the Ministry of Higher Education,Malaysia,under the Fundamental Research Grant Scheme FRGS/1/2023/STG06/UM/02/4(Project FP069-2023)。
文摘Electroosmotic transport and entropy generation play a decisive role in regulating efficiency,stability,and energy cost of non-Newtonian nanoblood flows in stenosed arteries,particularly with tapered geometries.Thisstudy develops a unified model to analyze ZnO-Williamson nanoblood flow through a stenosed artery with converging,diverging,and non-tapered configurations,incorporating electroosmosis,viscous dissipation,and entropy production.The arterial walls are assumed to be electrically charged with a no-slip condition to induce electroosmotic propulsionalong the endothelial surface.The partial differential equations are nondimensionalized to a coupled system ofnonlinear ordinary differential equations,which are solved numerically using a MATLAB-based shooting technique.Parametric investigation is conducted for Brinkman,Grashof,and Weissenberg numbers,ZnO fractional volume,volumetric flow rate,and Helmholtz-Smoluchowski velocity to quantify their influences on axial velocity,wall shearstress,impedance resistance,temperature distribution,entropy generation,Bejan number,and streamline topology.The axial velocity decreases radially with increasing Brinkman number for all arterial geometries.Increasing ZnOnanoparticles improves thermal transport owing to enhanced effective thermal conductivity but simultaneously elevatesentropy generation due to increased viscous dissipation.Higher Weissenberg numbers suppress entropy production bypromoting elastic stress redistribution and lowering shear-induced irreversibility.Impedance resistance decreases withincreasing stenosis height but increases with stenosis shape parameter and ZnO fractional volume.Streamline analysisshows that buoyancy and viscoelasticity significantly distort flow near the stenosis,while increasing electroosmoticvelocity stabilizes streamlines,suppresses recirculation,and reduces local shear stress and pressure fluctuations.Inconclusion,electroosmotic actuation is most effective in reducing flow resistance in the converging tapered artery,particularly at lower ZnO volume fractions.Overall,the findings highlight the potential of optimized electroosmoticactuation and controlled nanoparticle loading to minimize thermodynamic losses,regulate shear stress,and improveflow uniformity in stenosed vessels,with promising implications for electro-assisted drug delivery,nanotherapeutics,and bio-inspired vascular microfluidic systems.
基金supported by the National Natural Science Foundation of China(81760037)Yunling Scholar Project of Yunnan Province(YNWR-YLXZ-2019-0005)+1 种基金Hunan Provincial Innovation Platform and Talent Program(2018SK4004)Hunan Provincial Natural Science Foundation(2019JJ80048).
文摘The occurrence of severe thalassemia,an inherited blood disorder that is either blood-transfusiondependent or fatal,can be mitigated through carrier screening.Here,we aim to evaluate the effectiveness and outcomes of pre-conceptional and early pregnancy screening initiatives for severe thalassemia prevention in a diverse population of 28,043 women.Using next-generation sequencing(NGS),we identify 4,226(15.07%)thalassemia carriers across 29 ethnic groups and categorize them into high-(0.75%),low-(25.86%),and unknown-risk(69.19%)groups based on their spouses'screening results.Post-screening follow-up reveals 59 fetuses with severe thalassemia exclusively in high-risk couples,underscoring the efficacy of risk classification.Among 25,053 live births over 6 months of age,two severe thalassemia infants were born to unknown-risk couples,which was attributed to incomplete screening and late NGS-based testing for a rare variant.Notably,64 rare variants are identified in 287 individuals,highlighting the genetic heterogeneity of thalassemia.We also observe that migrant flow significantly impacts carrier rates,with 93.90%of migrants to Chenzhou originating from high-prevalence regions in southern China.Our study demonstrates that NGS-based screening during pre-conception and early pregnancy is effective for severe thalassemia prevention,emphasizing the need for continuous screening efforts in areas with high and underestimated prevalence.
文摘We are sorry for the mistakes of Affiliation,"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,Donghua University,Shanghai 201620,China"should be replaced by"a State Key Laboratory of Advanced Fiber Materials,Center for Advanced Low-Dimension Materials,College of Materials Science and Engineering,Donghua University,Shanghai 201620,China".We apologized for the inconvenience caused by this error.
基金supported by State Grid Shanghai Economic Research Institute under Grant No.SGTYHT/23-JS-004.
文摘Due to the complex structural hierarchy,with deeply nested associative relations between entities such as equipment,specifications,and business processes,intelligent power grid engineering is challenging.Meanwhile,limited by the fragmented data and loss of contextual information,the generated reports are prone to the problems such as content redundancy and omission of critical information,failing to meet the demands of efficient decision-making and accurate management in modern power systems.To address these issues,this paper proposes a knowledge graph(KG)-enhanced framework to automatically generate electric power engineering reports.In the KG construction phase,a feature-fused entity recognition model named BERT-BiLSTM-CRF is adopted to improve the accuracy of entity recognition in scenarios involving power engineering professional terminology,thereby solving the problem of ambiguous entity boundaries in traditional models;then a BERT-attention relation extraction model is proposed to enhance the completeness of extracting complex hierarchical and implicit relations in power grid data.In the report generation phase,an improved Transformer architecture is adopted to accurately transform structured knowledge into natural language reports that comply with engineering specifications,addressing the issue of semantic inconsistency caused by the loss of structural information in existing models.By validating with real-world projects,the results show that the proposed framework significantly outperforms existing baseline models in entity recognition,confirming its superiority and applicability in practical engineering.
基金The authors extend their appreciation to Prince Sattam bin Abdulaziz University for funding this research work through the project number(PSAU/2024/01/32082).
文摘In Human–Robot Interaction(HRI),generating robot trajectories that accurately reflect user intentions while ensuring physical realism remains challenging,especially in unstructured environments.In this study,we develop a multimodal framework that integrates symbolic task reasoning with continuous trajectory generation.The approach employs transformer models and adversarial training to map high-level intent to robotic motion.Information from multiple data sources,such as voice traits,hand and body keypoints,visual observations,and recorded paths,is integrated simultaneously.These signals are mapped into a shared representation that supports interpretable reasoning while enabling smooth and realistic motion generation.Based on this design,two different learning strategies are investigated.In the first step,grammar-constrained Linear Temporal Logic(LTL)expressions are created from multimodal human inputs.These expressions are subsequently decoded into robot trajectories.The second method generates trajectories directly from symbolic intent and linguistic data,bypassing an intermediate logical representation.Transformer encoders combine multiple types of information,and autoregressive transformer decoders generate motion sequences.Adding smoothness and speed limits during training increases the likelihood of physical feasibility.To improve the realism and stability of the generated trajectories during training,an adversarial discriminator is also included to guide them toward the distribution of actual robot motion.Tests on the NATSGLD dataset indicate that the complete system exhibits stable training behaviour and performance.In normalised coordinates,the logic-based pipeline has an Average Displacement Error(ADE)of 0.040 and a Final Displacement Error(FDE)of 0.036.The adversarial generator makes substantially more progress,reducing ADE to 0.021 and FDE to 0.018.Visual examination confirms that the generated trajectories closely align with observed motion patterns while preserving smooth temporal dynamics.
文摘The power systems economic and safety operation considering large-scale wind power penetration are now facing great challenges, which are based on reliable power supply and predictable load demands in the past. A rolling generation dispatch model based on ultra-short-term wind power forecast was proposed. In generation dispatch process, the model rolling correct not only the conventional units power output but also the power from wind farm, simultaneously. Second order Markov chain model was utilized to modify wind power prediction error state (WPPES) and update forecast results of wind power over the remaining dispatch periods. The prime-dual affine scaling interior point method was used to solve the proposed model that taken into account the constraints of multi-periods power balance, unit output adjustment, up spinning reserve and down spinning reserve.
文摘A controllable strategy for eliciting nuclear fusion is presented through ultra-intenselaser derived positron generation by a conceptual first physics perspective. The capability to generate positrons on demand in a controlled manner through an ultra-intense laser incident on a high atomic number target, such as gold, is the intrinsic core to the foundation of controllable nuclear fusion. Positron antimatter generated from the periphery of the fusion fuel pellet provides the basis for initiating the fusion reaction, which is regulated by controlling the operation of the ultra-intense laser. A dual pulsed Fast Ignition mechanism is selected to achieve the fusion reaction. Based on first physics performance analysis the controllable strategy for eliciting nuclear fusion through ultra-intenselaser derived positron generation offers a realizable means for achieving regulated nuclear fusion. A future perspective of the controllable fusion strategy addresses the opportunities and concerns of a pathway toward regulated nuclear fusion.
