The identification of novel physiological biomarkers in sweat requires real-time sampling and analysis.Here,we present the microfabrication of epidermal microfluidics within textiles via stereolithography(SLA)3D print...The identification of novel physiological biomarkers in sweat requires real-time sampling and analysis.Here,we present the microfabrication of epidermal microfluidics within textiles via stereolithography(SLA)3D printing.Flexible SLA resin defines impermeable fluid-guiding microstructures in textile microfluidic modules.Their vertical stacking reduces device footprint and required sample volume,and facilitates on-body fluid collection,storage,and transport.Embedded internal modules act as a reservoir and injection valve,releasing a defined volume of sweat to the sensing unit.The pressure gradient across the modules provides a vertically distributed,capillary-driven sweat flow,guided by the wicking power of the textile structure.Their full integration into apparels offers non-cumulative flow through an extended air-liquid interface,ensuring continuous sweat transfer and evaporation.For realtime sweat analysis,we use a remotely screen-printed potassium(K^(+))ion detector.This modular approach provides fabric-integrated,mechanically ergonomic microfluidics with multi-parameter detection through rapid additive manufacturing for advanced point-of-care diagnostics.展开更多
基金support of ID Fab at the Centre Microélectronique de Provence(Project funded by the European Regional Development Fund,the French state and local authorities)the Sustainable Development Goal(SDG)3:Health.E.I.and M.G particularly thank Francois Bernier for the experimental setting up and training on the SLA 3D printer and his valuable expertise in fast prototyping。
文摘The identification of novel physiological biomarkers in sweat requires real-time sampling and analysis.Here,we present the microfabrication of epidermal microfluidics within textiles via stereolithography(SLA)3D printing.Flexible SLA resin defines impermeable fluid-guiding microstructures in textile microfluidic modules.Their vertical stacking reduces device footprint and required sample volume,and facilitates on-body fluid collection,storage,and transport.Embedded internal modules act as a reservoir and injection valve,releasing a defined volume of sweat to the sensing unit.The pressure gradient across the modules provides a vertically distributed,capillary-driven sweat flow,guided by the wicking power of the textile structure.Their full integration into apparels offers non-cumulative flow through an extended air-liquid interface,ensuring continuous sweat transfer and evaporation.For realtime sweat analysis,we use a remotely screen-printed potassium(K^(+))ion detector.This modular approach provides fabric-integrated,mechanically ergonomic microfluidics with multi-parameter detection through rapid additive manufacturing for advanced point-of-care diagnostics.
