Background： Functional magnetic resonance imaging （fMRI） is a novel method for studying the changes of brain networks due to acupuncture treatment. In recent years, more and more studies have focused on the brain f...Background： Functional magnetic resonance imaging （fMRI） is a novel method for studying the changes of brain networks due to acupuncture treatment. In recent years, more and more studies have focused on the brain functional connectivity network of acupuncture stimulation. Objective： To offer an overview of the different influences of acupuncture on the brain functional connec- tivity network from studies using resting-state fMRI. Search strategy： The authors performed a systematic search according to PRISMA guidelines, The database PubMed was searched from January 1, 2006 to December 31, 2016 with restriction to human studies in English language. Inclusion criteria： Electronic searches were conducted in PubMed using the keywords ＂acupuncture＂ and ＂neuroimaging＂ or ＂resting-state fMRI＂ or ＂functional connectivity＂, Data extraction and analysis： Selection of included articles, data extraction and methodological quality assessments were respectively conducted by two review authors. Results： Forty-four resting-state fMRI studies were included in this systematic review according to inclu- sion criteria. Thirteen studies applied manual acupuncture vs. sham, four studies applied electro- acupuncture vs. sham, two studies also compared transcutaneous electrical acupoint stimulation vs. sham, and nine applied sham acupoint as control. Nineteen studies with a total number of 574 healthy subjects selected to perform fMRI only considered healthy adult volunteers. The brain functional connec- tivity of the patients had varying degrees of change. Compared with sham acupuncture, verum acupunc- ture could increase default mode network and sensorimotor network connectivity with pain-, affective- and memory-related brain areas. It has significantly greater connectivity of genuine acupuncture between the periaqueductal gray, anterior cingulate cortex, left posterior cingulate cortex, right anterior insula, limbic/paralimbic and precuneus compared with sham acupuncture. Some research had also shown that acupuncture could adjust the limbic-paralimbic-neocortical network, brainstem, cerebellum, subcortical and hippocampus brain areas. Conclusion： It can be presumed that the functional connectivity network is closely related to the mech- anism of acupuncture, and central integration plays a critical role in the acupuncture mechanism.展开更多
Functional diversity is significant to ecological processes of plant communities. We analyzed the variation of functional diversity of endangered species, Cercidiphyllum japonicum, communities along an elevational gra...Functional diversity is significant to ecological processes of plant communities. We analyzed the variation of functional diversity of endangered species, Cercidiphyllum japonicum, communities along an elevational gradient in the Shennongjia Reserve, central China. Sixty plots of 10 9 20 m from 1,350 to 2,050 m were set up and species composition, traits and environmental variables were measured and recorded. These data were analyzed using five functional diversity indices, functional attribute diversity, modified functional attribute diversity, plot based functional diversity, community based functional diversity and Rao＇s functional diversity indices（Rao＇s index）,Functional diversities of C. japonicum communities were rich and varied greatly. Functional diversity declined nonlinearly with increasing elevation. Functional diversity was significantly correlated with species richness and heterogeneity. Elevation was a key environmental variable influencing functional diversity and species diversity. The five functional diversity indices were all effective for measuring functional diversity of communities. Functional diversity can be used as an indicator of conservation efficiency of endangered species such as C. japonicum.展开更多
The regional specifi city of hippocampal abnormalities in late-life depression（LLD） has been demonstrated in previous studies. In this study,we sought to examine the functional connectivity（FC） patterns of hippoca...The regional specifi city of hippocampal abnormalities in late-life depression（LLD） has been demonstrated in previous studies. In this study,we sought to examine the functional connectivity（FC） patterns of hippocampal subregions in remitted late-onset depression（r LOD）,a special subtype of LLD. Fourteen r LOD patients and 18 healthy controls underwent clinical and cognitive evaluations as well as resting-state functional magnetic resonance imaging scans at baseline and at ~21 months of follow-up. Each hippocampus was divided into three parts,the cornu ammonis（CA）,the dentate gyrus,and the subicular complex,and then six seed-based hippocampal subregional networks were established.Longitudinal changes of the six networks over time were directly compared between the rL OD and control groups. From baseline to follow-up,the r LOD group showed a greater decline in connectivity of the left CA to the bilateral posterior cingulate cortex/precuneus（PCC/PCUN）,but showed increased connectivity of the right hippocampal subregional networks with the frontal cortex（bilateral medial prefrontal cortex/anterior cingulate cortex and supplementary motor area）. Further correlative analyses revealed thatthe longitudinal changes in FC between the left CA and PCC/PCUN were positively correlated with longitudinal changes in the Symbol Digit Modalities Test（r = 0.624,P = 0.017） and the Digit Span Test（r = 0.545,P = 0.044） scores in the r LOD group. These results may provide insights into the neurobiological mechanism underlying the cognitive dysfunction in r LOD patients.展开更多
Background:The Functional Movement Screen(FMS^(TM)) has become increasingly popular for identifying functional limitations in basic functional movements.This exploratory and descriptive study was undertaken to confirm...Background:The Functional Movement Screen(FMS^(TM)) has become increasingly popular for identifying functional limitations in basic functional movements.This exploratory and descriptive study was undertaken to confirm feasibility of performing the FMS^(TM) in older active adults,assess prevalence of asymmetries and to evaluate the relationship between functional movement ability,age,physical activity levels and body mass index(BMI).Methods:This is an observational study;97 men(n = 53) and women(n = 44) between the ages of 52 and 83 participated.BMI was computed and self-reported physical activity levels were obtained.Subjects were grouped by age(5-year intervals),BMI(normal,over-weight,and obese)and sex.Each participant's performance on the FMS^(TM) was digitally recorded for later analysis.Results:The youngest age group(50–54 years) scored highest in all seven tests and the oldest age group(75+) scored lowest in most of the tests compared to all other age groups.The subjects in the 'normal weight' group performed no different than those who were in the 'overweight' group;both groups performed better than the 'obese' group.Of the 97 participants 54 had at least one asymmetry.The pairwise correlations between the total FMS^(TM) score and age(r =-0.531),BMI(r =-0.270),and the measure of activity level(r = 0.287) were significant(p < 0.01 for all).Conclusion:FMS^(TM) scores decline with increased BMI,increased age,and decreased activity level.The screen identifies range of motion-and strength-related asymmetries.The FMS^(TM) can be used to assess functional limitations and asymmetries.Future research should evaluate if a higher total FMS^(TM) score is related to fewer falls or injuries in the older population.展开更多
Functional networks(FNs)hold significant promise in understanding brain function.Independent component analysis(ICA)has been applied in estimating FNs from functional magnetic resonance imaging(fMRI).However,determini...Functional networks(FNs)hold significant promise in understanding brain function.Independent component analysis(ICA)has been applied in estimating FNs from functional magnetic resonance imaging(fMRI).However,determining an optimal model order for ICA remains challenging,leading to criticism about the reliability of FN estimation.Here,we propose a SMART(splitting-merging assisted reliable)ICA method that automatically extracts reliable FNs by clustering independent components(ICs)obtained from multi-model-order ICA using a simplified graph while providing linkages among FNs deduced from different-model orders.We extend SMART ICA to multi-subject fMRI analysis,validating its effectiveness using simulated and real fMRI data.Based on simulated data,the method accurately estimates both group-common and group-unique components and demonstrates robustness to parameters.Using two age-matched cohorts of resting fMRI data comprising 1,950 healthy subjects,the resulting reliable group-level FNs are greatly similar between the two cohorts,and interestingly the subject-specific FNs show progressive changes while age increases.Furthermore,both small-scale and large-scale brain FN templates are provided as benchmarks for future studies.Taken together,SMART ICA can automatically obtain reliable FNs in analyzing multi-subject fMRI data,while also providing linkages between different FNs.展开更多
Aphasia is an acquired language disorder that is a common consequence of stroke.The pathogenesis of the disease is not fully understood,and as a result,current treatment options are not satisfactory.Here,we used blood...Aphasia is an acquired language disorder that is a common consequence of stroke.The pathogenesis of the disease is not fully understood,and as a result,current treatment options are not satisfactory.Here,we used blood oxygenation level-dependent functional magnetic resonance imaging to evaluate the activation of bilateral cortices in patients with Broca＇s aphasia 1 to 3 months after stroke.Our results showed that language expression was associated with multiple brain regions in which the right hemisphere participated in the generation of language.The activation areas in the left hemisphere of aphasia patients were significantly smaller compared with those in healthy adults.The activation frequency,volumes,and intensity in the regions related to language,such as the left inferior frontal gyrus（Broca＇s area）,the left superior temporal gyrus,and the right inferior frontal gyrus（the mirror region of Broca＇s area）,were lower in patients compared with healthy adults.In contrast,activation in the right superior temporal gyrus,the bilateral superior parietal lobule,and the left inferior temporal gyrus was stronger in patients compared with healthy controls.These results suggest that the right inferior frontal gyrus plays a role in the recovery of language function in the subacute stage of stroke-related aphasia by increasing the engagement of related brain areas.展开更多
In recent years,rumor spreading has caused widespread public panic and affected the whole social harmony and stability.Consequently,how to control the rumor spreading effectively and reduce its negative influence urge...In recent years,rumor spreading has caused widespread public panic and affected the whole social harmony and stability.Consequently,how to control the rumor spreading effectively and reduce its negative influence urgently needs people to pay much attention.In this paper,we mainly study the near-optimal control of a stochastic rumor spreading model with Holling II functional response function and imprecise parameters.Firstly,the science knowledge propagation and the refutation mechanism as the control strategies are introduced into a stochastic rumor spreading model.Then,some sufficient and necessary conditions for the near-optimal control of the stochastic rumor spreading model are discussed respectively.Finally,through some numerical simulations,the validity and availability of theoretical analysis is verified.Meanwhile,it shows the significance and effectiveness of the proposed control strategies on controlling rumor spreading,and demonstrates the influence of stochastic disturbance and imprecise parameters on the process of rumor spreading.展开更多
A meshless radial basis function （RBF） collocation method based on the Eringen nonlocal elasticity theory is developed to calculate the band structures of ternary and quaternary nanoscale multi-layered phononic crys...A meshless radial basis function （RBF） collocation method based on the Eringen nonlocal elasticity theory is developed to calculate the band structures of ternary and quaternary nanoscale multi-layered phononic crystals （PNCs） with functionally graded （FG） interlayers. Detailed calculations are performed for anti-plane transverse waves propagating in such PNCs. The influences of FG and homogeneous interlayers, component number, nonlocal interface imperfections and nanoscale size on cut-off frequency and band structures are investigated in detail. Numerical results show that these factors have significant effects on band structures at the macroscopic and microscopic scales.展开更多
In present paper, the non-equilibrium Green function(NEGF) method along with the density functional theory(DFT) are used to investigate the effect of width on transport and electronic properties of armchair graphyne(...In present paper, the non-equilibrium Green function(NEGF) method along with the density functional theory(DFT) are used to investigate the effect of width on transport and electronic properties of armchair graphyne(γ-graphyne) nanoribbons. The results show that all the studied nanoribbons are semiconductor and their band gaps decrease as the widths of nanoribbons increase, which will result in increasing current at a certain voltage. Also our results show the promising application of armchair graphyne nanoribbons in nano-electrical devices.展开更多
Totally three articles focusing on functional magnetic resonance imaging features of brain function in the activated brain regions of stroke patients undergoing acupuncture on the healthy limbs and healthy controls un...Totally three articles focusing on functional magnetic resonance imaging features of brain function in the activated brain regions of stroke patients undergoing acupuncture on the healthy limbs and healthy controls undergoing acupuncture on the lower extremities are published in three issues. We hope that our readers find these papers useful to their research.展开更多
Stroke survivors often present with abnormal gait, movement training can improve the walking performance post-stroke, and functional MRI can objectively evaluate the brain functions before and after movement training....Stroke survivors often present with abnormal gait, movement training can improve the walking performance post-stroke, and functional MRI can objectively evaluate the brain functions before and after movement training. This paper analyzes the functional MRI changes in patients with ischemic stroke after treadmill training with voluntary and passive ankle dorsiflexion. Functional MRI showed that there are some changes in some regions of patients with ischemic stroke including primary sensorimotor cortex, supplementary motor area and cingulate motor area after treadmill training. These findings suggest that treadmill training likely improves ischemic stroke patients＇ lower limb functions and gait performance and promotes stroke recovery by changing patients＇ brain plasticity; meanwhile, the novel treadmill training methods can better training effects.展开更多
We propose that the core mass function(CMF)can be driven by filament fragmentation.To model a star-forming system of filaments and fibers,we develop a fractal and turbulent tree with a fractal dimension of 2 and a Lar...We propose that the core mass function(CMF)can be driven by filament fragmentation.To model a star-forming system of filaments and fibers,we develop a fractal and turbulent tree with a fractal dimension of 2 and a Larson's law exponent(β)of 0.5.The fragmentation driven by convergent flows along the splines of the fractal tree yields a Kroupa-IMF-like CMF that can be divided into three power-law segments with exponentsα=-0.5,-1.5,and-2,respectively.The turnover masses of the derived CMF are approximately four times those of the Kroupa IMF,corresponding to a star formation efficiency of 0.25.Adoptingβ=1/3,which leads to fractional Brownian motion along the filament,may explain a steeper CMF at the high-mass end,withα=-3.33 close to that of the Salpeter IMF.We suggest that the fibers of the tree are basic building blocks of star formation,with similar properties across different clouds,establishing a common density threshold for star formation and leading to a universal CMF.展开更多
The exact minimax penalty function method is used to solve a noncon- vex differentiable optimization problem with both inequality and equality constraints. The conditions for exactness of the penalization for the exac...The exact minimax penalty function method is used to solve a noncon- vex differentiable optimization problem with both inequality and equality constraints. The conditions for exactness of the penalization for the exact minimax penalty function method are established by assuming that the functions constituting the considered con- strained optimization problem are invex with respect to the same function η （with the exception of those equality constraints for which the associated Lagrange multipliers are negative these functions should be assumed to be incave with respect to η）. Thus, a threshold of the penalty parameter is given such that, for all penalty parameters exceeding this threshold, equivalence holds between the set of optimal solutions in the considered constrained optimization problem and the set of minimizer in its associated penalized problem with an exact minimax penalty function. It is shown that coercivity is not suf- ficient to prove the results.展开更多
In the present paper, we derive some third-order differential subordination results for analytic functions in the open unit disk, using the operator Bcκf by means of normalized form of the generalized Bessel function...In the present paper, we derive some third-order differential subordination results for analytic functions in the open unit disk, using the operator Bcκf by means of normalized form of the generalized Bessel functions of the first kind, which is defined as z（Bκ＋1^c f（z））′= κBκ^c f（z）-（κ- 1）Bκ＋1^c f（z）,where b, c, p ∈ C and κ = p ＋（b ＋ 1）/2 ∈ C ／ Z0^-（Z0^-= {0,-1,-2, … }）. The results are obtained by considering suitable classes of admissible functions. Various known or new special cases of our main results are also pointed out.展开更多
In this paper, a new subclass N_Σ^（h,p）（m, λ, μ） of analytic and bi-univalent functions in the open unit disk U is defined by salagean operator. We obtain coefficients bounds ｜a_2｜ and ｜a_3｜ for functions o...In this paper, a new subclass N_Σ^（h,p）（m, λ, μ） of analytic and bi-univalent functions in the open unit disk U is defined by salagean operator. We obtain coefficients bounds ｜a_2｜ and ｜a_3｜ for functions of the class. Moreover, we verify Brannan and Clunie＇s conjecture ｜a_2｜ ≤2^（1/2）for some of our classes. The results in this paper extend many results recently researched by many authors.展开更多
We consider the limiting property of the distribution function of L^p function at endpoints 0 and ∞ and prove that for λ 〉 0 the following two equations limλ→＋∞λ^p（{x ： ｜f（x）｜ 〉 λ}） = 0, limλ→0＋λ^...We consider the limiting property of the distribution function of L^p function at endpoints 0 and ∞ and prove that for λ 〉 0 the following two equations limλ→＋∞λ^p（{x ： ｜f（x）｜ 〉 λ}） = 0, limλ→0＋λ^p（{x ： ｜f（x）｜ 〉 λ}） = 0hold for f ∈ L^p（Rn） with 1 ≤ p 〈 ∞. This result is naturally applied to many operators of type（p, q） as well.展开更多
Based on the existing continuous borehole strain observation,the multiquadric function fitting method was used to deal with time series data. The impact of difference kernel function parameters was discussed to obtain...Based on the existing continuous borehole strain observation,the multiquadric function fitting method was used to deal with time series data. The impact of difference kernel function parameters was discussed to obtain a valuable fitting result,from which the physical connotation of the original data and its possible applications were analyzed.Meanwhile,a brief comparison was made between the results of multiquadric function fitting and polynomial fitting.展开更多
Four alternative functions are used for lilting tree height and diameter growth models for mongolian oak(Quercus mongolica Fisch et Turcz)The data set includes 1250 random trees and 755 dominant trees coming from 510l...Four alternative functions are used for lilting tree height and diameter growth models for mongolian oak(Quercus mongolica Fisch et Turcz)The data set includes 1250 random trees and 755 dominant trees coming from 510lemporary plots The resultsshow that the Richads function is the best model for predicting height diameter at breast height(DBH) and dominant height from age The average growth curveof domnant height is used as a guide curve for the construction of a site index table which is partially validated using an independent data set The Mischerlic function is the bestmodel for estimating height and dominam height from DBH展开更多
In this paper, we introduce and investigate a new subclass of the function class ∑. of bi-univalent functions of the Mocanu-convex type defined in the open unit disk, satisfy Ma and Minda subordination conditions. Fu...In this paper, we introduce and investigate a new subclass of the function class ∑. of bi-univalent functions of the Mocanu-convex type defined in the open unit disk, satisfy Ma and Minda subordination conditions. Furthermore, we find estimates on the Taylor-Maclaurin coefficients ｜a2｜ and ｜a3｜ for functions in the new subclass introduced here. Further Application of Hohlov operator to this class is obtained. Several （known or new） consequences of the results are also pointed out.展开更多
BACKGROUND： Ultraviolet blood irradiation and oxygenation （UBIO） has obtained better clinical effect in treating acute cerebral infarction, but the mechanism underlying this effect remains unclear. OBJECTIVE： To o...BACKGROUND： Ultraviolet blood irradiation and oxygenation （UBIO） has obtained better clinical effect in treating acute cerebral infarction, but the mechanism underlying this effect remains unclear. OBJECTIVE： To observe the effect of UBIO on the nerve function and activities of K^＋-Na^＋-ATPase and Ca2^＋-Mg2^＋-ATPase activities on the red blood cell （RBC） membrane of patients with acute cerebral infarction. DESIGN： A randomized and controlled study.SETTING： Department of Neurology, Xiangfan Central Hospital.PARTICIPANTS： From January 2000 to December 2001, excluding those above 70 years old, 58 cases of 700 patients with acute cerebral infarction admitted in the Department of Neurology, Xiangfan Central Hospital, were recruited and divided into two groups according to the random number table： UBIO treated group （n=28）, including 17 males and 11 females, aged 40-68 years; and control group （n=30）, including 20 males and 10 females, aged 44-69 years. All the patients agreed to participate in the therapeutic program and detected items. The general informations were comparable without obvious differences between the two groups （P 〉 0.05）.METHODS： ① The patients in both groups received routine treatments, besides, those in the UBIO treated group were given UBIO treatment by using the XL-200 type therapeutic apparatus produced in Shijiazhuang, whose ultraviolet wave was set at 253.7 nm with the energy density of 0.568 J/m^2 per second, UBIO treatment started from the second day after admission, once every other day, with a single course consisting of 5-7 treatments. ② In the UBIO treated group, the venous blood was sampled before and after the first, third and the completion of the treatment course respectively, the venous blood was taken at each corresponding time point in the control group. After centrifugation of the blood at 10 000 rounds per minute, the RBC membrane was separated and then the activities of K^＋-Na^＋-ATPase and Ca2^＋-Mg2^＋-ATPase were detected by means of phosphorus determination.③ The nerve function was scored before and after treatment in both groups with European stroke scale, which included 13 items, the total score was 0-100 points, the higher the score, the better the nerve function. MAIN OUTCOME MEASURES ：①Score of European stroke scale before and after treatment in both groups.② Comparison of the activities of K^＋-Na^＋-ATPase and Ca2^＋-Mg2^＋-ATPase on RBC membrane between the two groups before treatment and after the first, third and the completion of the treatment. RESULTS： All the 58 patients with cerebral infarction were involved in the analysis of results.① The score of European stroke scale had no obvious difference between the two groups [（49.31±11.48）, （50.58±12.63）, P 〉 0.05], and it was obviously higher in the UBIO treated group than in the control group after treatment [84.66±13.75）, （77.05±11.17）, P 〈 0.05].②The activity of K^＋-Na^＋-ATPase on RBC membrane in the UBIO treated group was significantly increased after the first and third treatment as compared with before treatment [（31.56±19.25）, （27.64±15.83）, （17.67±13.83）, P 〈 0.01], it was still higher after the completion of the treatment than before treatment without obvious difference [（20.86±14.53）, P 〉 0.05]. After the first and third treatment, it was obviously higher in the UBIO treated group than in the control group [19.31±11.88）, （17.44±10.42）, P 〈 0.01]. ③ In the UBIO treated group, Ca2^＋-Mg2^＋-ATPase activity on RBC membrane significantly increased after the first treatment and remained higher than the pre-treatment level throughout the treatment [（27.49±14.72）, （17.41±4.82）, P 〈 0.01]. The activity of Ca2^＋-Mg2^＋-ATPase on RBC membrane was markedly higher in the UBIO treated group than in the control group after after the first, third and the completion of treatment respectively [（24.83±12.88）, （17.70±5.69）; （28.08±13.44）, （16.32±5.29）; （17.42±6.04）, P〈 0.05-0.01]. CONCLUSION： The effect of UBIO treatment against acute cerebral infarction may be mediated by the increased K^＋-Na^＋ ATPase and Ca2^＋-Mg2^＋-ATPase activities on RBC membrane, which enhances the RBC transformation ability so as to lower RBC aggregation and correct high blood viscosity.展开更多
基金supported by the National Natural Science Foundation of China(No.81473784)University Science Research Project of Anhui Province of China(No.KJ2017A298)+1 种基金the Key Project of the Youth Elite Support Plan in Universities of Anhui Province of China(No.gxyq ZD2016134)Construction Project of Scientific Research Innovation Platform of Anhui Province of China(No.2015TD033)
文摘Background： Functional magnetic resonance imaging （fMRI） is a novel method for studying the changes of brain networks due to acupuncture treatment. In recent years, more and more studies have focused on the brain functional connectivity network of acupuncture stimulation. Objective： To offer an overview of the different influences of acupuncture on the brain functional connec- tivity network from studies using resting-state fMRI. Search strategy： The authors performed a systematic search according to PRISMA guidelines, The database PubMed was searched from January 1, 2006 to December 31, 2016 with restriction to human studies in English language. Inclusion criteria： Electronic searches were conducted in PubMed using the keywords ＂acupuncture＂ and ＂neuroimaging＂ or ＂resting-state fMRI＂ or ＂functional connectivity＂, Data extraction and analysis： Selection of included articles, data extraction and methodological quality assessments were respectively conducted by two review authors. Results： Forty-four resting-state fMRI studies were included in this systematic review according to inclu- sion criteria. Thirteen studies applied manual acupuncture vs. sham, four studies applied electro- acupuncture vs. sham, two studies also compared transcutaneous electrical acupoint stimulation vs. sham, and nine applied sham acupoint as control. Nineteen studies with a total number of 574 healthy subjects selected to perform fMRI only considered healthy adult volunteers. The brain functional connec- tivity of the patients had varying degrees of change. Compared with sham acupuncture, verum acupunc- ture could increase default mode network and sensorimotor network connectivity with pain-, affective- and memory-related brain areas. It has significantly greater connectivity of genuine acupuncture between the periaqueductal gray, anterior cingulate cortex, left posterior cingulate cortex, right anterior insula, limbic/paralimbic and precuneus compared with sham acupuncture. Some research had also shown that acupuncture could adjust the limbic-paralimbic-neocortical network, brainstem, cerebellum, subcortical and hippocampus brain areas. Conclusion： It can be presumed that the functional connectivity network is closely related to the mech- anism of acupuncture, and central integration plays a critical role in the acupuncture mechanism.
基金financially supported by the National Natural Science Foundation of China(Grant No:31170494)the Specialized Research Fund for the Doctoral Program of Higher Education(Grant No.20120003110024)
文摘Functional diversity is significant to ecological processes of plant communities. We analyzed the variation of functional diversity of endangered species, Cercidiphyllum japonicum, communities along an elevational gradient in the Shennongjia Reserve, central China. Sixty plots of 10 9 20 m from 1,350 to 2,050 m were set up and species composition, traits and environmental variables were measured and recorded. These data were analyzed using five functional diversity indices, functional attribute diversity, modified functional attribute diversity, plot based functional diversity, community based functional diversity and Rao＇s functional diversity indices（Rao＇s index）,Functional diversities of C. japonicum communities were rich and varied greatly. Functional diversity declined nonlinearly with increasing elevation. Functional diversity was significantly correlated with species richness and heterogeneity. Elevation was a key environmental variable influencing functional diversity and species diversity. The five functional diversity indices were all effective for measuring functional diversity of communities. Functional diversity can be used as an indicator of conservation efficiency of endangered species such as C. japonicum.
基金supported by the National Natural Science Foundation of China (30825014,81061120529,30970814,81371488,91132727 and 30830046)the Key Program for Clinical Medicine and Science and Technology,Jiangsu Provincial Clinical Medical Research Center,China (BL2013025)
文摘The regional specifi city of hippocampal abnormalities in late-life depression（LLD） has been demonstrated in previous studies. In this study,we sought to examine the functional connectivity（FC） patterns of hippocampal subregions in remitted late-onset depression（r LOD）,a special subtype of LLD. Fourteen r LOD patients and 18 healthy controls underwent clinical and cognitive evaluations as well as resting-state functional magnetic resonance imaging scans at baseline and at ~21 months of follow-up. Each hippocampus was divided into three parts,the cornu ammonis（CA）,the dentate gyrus,and the subicular complex,and then six seed-based hippocampal subregional networks were established.Longitudinal changes of the six networks over time were directly compared between the rL OD and control groups. From baseline to follow-up,the r LOD group showed a greater decline in connectivity of the left CA to the bilateral posterior cingulate cortex/precuneus（PCC/PCUN）,but showed increased connectivity of the right hippocampal subregional networks with the frontal cortex（bilateral medial prefrontal cortex/anterior cingulate cortex and supplementary motor area）. Further correlative analyses revealed thatthe longitudinal changes in FC between the left CA and PCC/PCUN were positively correlated with longitudinal changes in the Symbol Digit Modalities Test（r = 0.624,P = 0.017） and the Digit Span Test（r = 0.545,P = 0.044） scores in the r LOD group. These results may provide insights into the neurobiological mechanism underlying the cognitive dysfunction in r LOD patients.
文摘Background:The Functional Movement Screen(FMS^(TM)) has become increasingly popular for identifying functional limitations in basic functional movements.This exploratory and descriptive study was undertaken to confirm feasibility of performing the FMS^(TM) in older active adults,assess prevalence of asymmetries and to evaluate the relationship between functional movement ability,age,physical activity levels and body mass index(BMI).Methods:This is an observational study;97 men(n = 53) and women(n = 44) between the ages of 52 and 83 participated.BMI was computed and self-reported physical activity levels were obtained.Subjects were grouped by age(5-year intervals),BMI(normal,over-weight,and obese)and sex.Each participant's performance on the FMS^(TM) was digitally recorded for later analysis.Results:The youngest age group(50–54 years) scored highest in all seven tests and the oldest age group(75+) scored lowest in most of the tests compared to all other age groups.The subjects in the 'normal weight' group performed no different than those who were in the 'overweight' group;both groups performed better than the 'obese' group.Of the 97 participants 54 had at least one asymmetry.The pairwise correlations between the total FMS^(TM) score and age(r =-0.531),BMI(r =-0.270),and the measure of activity level(r = 0.287) were significant(p < 0.01 for all).Conclusion:FMS^(TM) scores decline with increased BMI,increased age,and decreased activity level.The screen identifies range of motion-and strength-related asymmetries.The FMS^(TM) can be used to assess functional limitations and asymmetries.Future research should evaluate if a higher total FMS^(TM) score is related to fewer falls or injuries in the older population.
基金supported by the National Natural Science Foundation of China(62076157 and 61703253)the Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Province(20210033)the National Institutes of Health(R01MH123610 and R01EB006841).
文摘Functional networks(FNs)hold significant promise in understanding brain function.Independent component analysis(ICA)has been applied in estimating FNs from functional magnetic resonance imaging(fMRI).However,determining an optimal model order for ICA remains challenging,leading to criticism about the reliability of FN estimation.Here,we propose a SMART(splitting-merging assisted reliable)ICA method that automatically extracts reliable FNs by clustering independent components(ICs)obtained from multi-model-order ICA using a simplified graph while providing linkages among FNs deduced from different-model orders.We extend SMART ICA to multi-subject fMRI analysis,validating its effectiveness using simulated and real fMRI data.Based on simulated data,the method accurately estimates both group-common and group-unique components and demonstrates robustness to parameters.Using two age-matched cohorts of resting fMRI data comprising 1,950 healthy subjects,the resulting reliable group-level FNs are greatly similar between the two cohorts,and interestingly the subject-specific FNs show progressive changes while age increases.Furthermore,both small-scale and large-scale brain FN templates are provided as benchmarks for future studies.Taken together,SMART ICA can automatically obtain reliable FNs in analyzing multi-subject fMRI data,while also providing linkages between different FNs.
基金supported by the Natural Science Foundation of Guangdong Province of China,No.2016A030313327the Science and Technology Planning Project of Guangzhou City of China,No.201607010185+1 种基金the Science and Technology Planning Project of Guangdong Province of China,No.2016A020215226the National Natural Science Foundation of China,No.81401869
文摘Aphasia is an acquired language disorder that is a common consequence of stroke.The pathogenesis of the disease is not fully understood,and as a result,current treatment options are not satisfactory.Here,we used blood oxygenation level-dependent functional magnetic resonance imaging to evaluate the activation of bilateral cortices in patients with Broca＇s aphasia 1 to 3 months after stroke.Our results showed that language expression was associated with multiple brain regions in which the right hemisphere participated in the generation of language.The activation areas in the left hemisphere of aphasia patients were significantly smaller compared with those in healthy adults.The activation frequency,volumes,and intensity in the regions related to language,such as the left inferior frontal gyrus（Broca＇s area）,the left superior temporal gyrus,and the right inferior frontal gyrus（the mirror region of Broca＇s area）,were lower in patients compared with healthy adults.In contrast,activation in the right superior temporal gyrus,the bilateral superior parietal lobule,and the left inferior temporal gyrus was stronger in patients compared with healthy controls.These results suggest that the right inferior frontal gyrus plays a role in the recovery of language function in the subacute stage of stroke-related aphasia by increasing the engagement of related brain areas.
基金Project supported by the Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learningthe Project for the Natural Science Foundation of Shanghai,China(Grant No.21ZR1444100)the Project for the National Natural Science Foundation of China(Grant Nos.72174121,71774111,71871144,and 71804047)。
文摘In recent years,rumor spreading has caused widespread public panic and affected the whole social harmony and stability.Consequently,how to control the rumor spreading effectively and reduce its negative influence urgently needs people to pay much attention.In this paper,we mainly study the near-optimal control of a stochastic rumor spreading model with Holling II functional response function and imprecise parameters.Firstly,the science knowledge propagation and the refutation mechanism as the control strategies are introduced into a stochastic rumor spreading model.Then,some sufficient and necessary conditions for the near-optimal control of the stochastic rumor spreading model are discussed respectively.Finally,through some numerical simulations,the validity and availability of theoretical analysis is verified.Meanwhile,it shows the significance and effectiveness of the proposed control strategies on controlling rumor spreading,and demonstrates the influence of stochastic disturbance and imprecise parameters on the process of rumor spreading.
基金the supports by the National Natural Science Foundation of China (nos.11002026,11372039)Beijing Natural Science Foundation (no.3133039)the Scientific Research Foundation for the Returned (no.20121832001)
文摘A meshless radial basis function （RBF） collocation method based on the Eringen nonlocal elasticity theory is developed to calculate the band structures of ternary and quaternary nanoscale multi-layered phononic crystals （PNCs） with functionally graded （FG） interlayers. Detailed calculations are performed for anti-plane transverse waves propagating in such PNCs. The influences of FG and homogeneous interlayers, component number, nonlocal interface imperfections and nanoscale size on cut-off frequency and band structures are investigated in detail. Numerical results show that these factors have significant effects on band structures at the macroscopic and microscopic scales.
文摘In present paper, the non-equilibrium Green function(NEGF) method along with the density functional theory(DFT) are used to investigate the effect of width on transport and electronic properties of armchair graphyne(γ-graphyne) nanoribbons. The results show that all the studied nanoribbons are semiconductor and their band gaps decrease as the widths of nanoribbons increase, which will result in increasing current at a certain voltage. Also our results show the promising application of armchair graphyne nanoribbons in nano-electrical devices.
文摘Totally three articles focusing on functional magnetic resonance imaging features of brain function in the activated brain regions of stroke patients undergoing acupuncture on the healthy limbs and healthy controls undergoing acupuncture on the lower extremities are published in three issues. We hope that our readers find these papers useful to their research.
基金supported by the Natural Science Foundation of China,No.30973165
文摘Stroke survivors often present with abnormal gait, movement training can improve the walking performance post-stroke, and functional MRI can objectively evaluate the brain functions before and after movement training. This paper analyzes the functional MRI changes in patients with ischemic stroke after treadmill training with voluntary and passive ankle dorsiflexion. Functional MRI showed that there are some changes in some regions of patients with ischemic stroke including primary sensorimotor cortex, supplementary motor area and cingulate motor area after treadmill training. These findings suggest that treadmill training likely improves ischemic stroke patients＇ lower limb functions and gait performance and promotes stroke recovery by changing patients＇ brain plasticity; meanwhile, the novel treadmill training methods can better training effects.
基金support of the Strategic Priority Research Program of the Chinese Academy of Sciences under grant No.XDB0800303the National Key R&D Program of China under grant No.2022YFA1603100the National Natural Science Foundation of China(NSFC,Grant No.12203086)。
文摘We propose that the core mass function(CMF)can be driven by filament fragmentation.To model a star-forming system of filaments and fibers,we develop a fractal and turbulent tree with a fractal dimension of 2 and a Larson's law exponent(β)of 0.5.The fragmentation driven by convergent flows along the splines of the fractal tree yields a Kroupa-IMF-like CMF that can be divided into three power-law segments with exponentsα=-0.5,-1.5,and-2,respectively.The turnover masses of the derived CMF are approximately four times those of the Kroupa IMF,corresponding to a star formation efficiency of 0.25.Adoptingβ=1/3,which leads to fractional Brownian motion along the filament,may explain a steeper CMF at the high-mass end,withα=-3.33 close to that of the Salpeter IMF.We suggest that the fibers of the tree are basic building blocks of star formation,with similar properties across different clouds,establishing a common density threshold for star formation and leading to a universal CMF.
文摘The exact minimax penalty function method is used to solve a noncon- vex differentiable optimization problem with both inequality and equality constraints. The conditions for exactness of the penalization for the exact minimax penalty function method are established by assuming that the functions constituting the considered con- strained optimization problem are invex with respect to the same function η （with the exception of those equality constraints for which the associated Lagrange multipliers are negative these functions should be assumed to be incave with respect to η）. Thus, a threshold of the penalty parameter is given such that, for all penalty parameters exceeding this threshold, equivalence holds between the set of optimal solutions in the considered constrained optimization problem and the set of minimizer in its associated penalized problem with an exact minimax penalty function. It is shown that coercivity is not suf- ficient to prove the results.
基金partly supported by the Natural Science Foundation of China(11271045)the Higher School Doctoral Foundation of China(20100003110004)+2 种基金the Natural Science Foundation of Inner Mongolia of China(2010MS0117)athe Higher School Foundation of Inner Mongolia of China(NJZY13298)the Commission for the Scientific Research Projects of Kafkas Univertsity(2012-FEF-30)
文摘In the present paper, we derive some third-order differential subordination results for analytic functions in the open unit disk, using the operator Bcκf by means of normalized form of the generalized Bessel functions of the first kind, which is defined as z（Bκ＋1^c f（z））′= κBκ^c f（z）-（κ- 1）Bκ＋1^c f（z）,where b, c, p ∈ C and κ = p ＋（b ＋ 1）/2 ∈ C ／ Z0^-（Z0^-= {0,-1,-2, … }）. The results are obtained by considering suitable classes of admissible functions. Various known or new special cases of our main results are also pointed out.
基金Supported by the National Natural Science Foundation of China(Grant No.11401186)the Research Fund from Engineering and Technology College Yangtze University(Grant No.15J0802)
文摘In this paper, a new subclass N_Σ^（h,p）（m, λ, μ） of analytic and bi-univalent functions in the open unit disk U is defined by salagean operator. We obtain coefficients bounds ｜a_2｜ and ｜a_3｜ for functions of the class. Moreover, we verify Brannan and Clunie＇s conjecture ｜a_2｜ ≤2^（1/2）for some of our classes. The results in this paper extend many results recently researched by many authors.
基金Supported by the National Natural Science Foundation of China(Grant Nos.114713091127116211561062)
文摘We consider the limiting property of the distribution function of L^p function at endpoints 0 and ∞ and prove that for λ 〉 0 the following two equations limλ→＋∞λ^p（{x ： ｜f（x）｜ 〉 λ}） = 0, limλ→0＋λ^p（{x ： ｜f（x）｜ 〉 λ}） = 0hold for f ∈ L^p（Rn） with 1 ≤ p 〈 ∞. This result is naturally applied to many operators of type（p, q） as well.
基金sponsored by the Annual Earthquake Tracking Task,CEA(2017010214)
文摘Based on the existing continuous borehole strain observation,the multiquadric function fitting method was used to deal with time series data. The impact of difference kernel function parameters was discussed to obtain a valuable fitting result,from which the physical connotation of the original data and its possible applications were analyzed.Meanwhile,a brief comparison was made between the results of multiquadric function fitting and polynomial fitting.
文摘Four alternative functions are used for lilting tree height and diameter growth models for mongolian oak(Quercus mongolica Fisch et Turcz)The data set includes 1250 random trees and 755 dominant trees coming from 510lemporary plots The resultsshow that the Richads function is the best model for predicting height diameter at breast height(DBH) and dominant height from age The average growth curveof domnant height is used as a guide curve for the construction of a site index table which is partially validated using an independent data set The Mischerlic function is the bestmodel for estimating height and dominam height from DBH
文摘In this paper, we introduce and investigate a new subclass of the function class ∑. of bi-univalent functions of the Mocanu-convex type defined in the open unit disk, satisfy Ma and Minda subordination conditions. Furthermore, we find estimates on the Taylor-Maclaurin coefficients ｜a2｜ and ｜a3｜ for functions in the new subclass introduced here. Further Application of Hohlov operator to this class is obtained. Several （known or new） consequences of the results are also pointed out.
文摘BACKGROUND： Ultraviolet blood irradiation and oxygenation （UBIO） has obtained better clinical effect in treating acute cerebral infarction, but the mechanism underlying this effect remains unclear. OBJECTIVE： To observe the effect of UBIO on the nerve function and activities of K^＋-Na^＋-ATPase and Ca2^＋-Mg2^＋-ATPase activities on the red blood cell （RBC） membrane of patients with acute cerebral infarction. DESIGN： A randomized and controlled study.SETTING： Department of Neurology, Xiangfan Central Hospital.PARTICIPANTS： From January 2000 to December 2001, excluding those above 70 years old, 58 cases of 700 patients with acute cerebral infarction admitted in the Department of Neurology, Xiangfan Central Hospital, were recruited and divided into two groups according to the random number table： UBIO treated group （n=28）, including 17 males and 11 females, aged 40-68 years; and control group （n=30）, including 20 males and 10 females, aged 44-69 years. All the patients agreed to participate in the therapeutic program and detected items. The general informations were comparable without obvious differences between the two groups （P 〉 0.05）.METHODS： ① The patients in both groups received routine treatments, besides, those in the UBIO treated group were given UBIO treatment by using the XL-200 type therapeutic apparatus produced in Shijiazhuang, whose ultraviolet wave was set at 253.7 nm with the energy density of 0.568 J/m^2 per second, UBIO treatment started from the second day after admission, once every other day, with a single course consisting of 5-7 treatments. ② In the UBIO treated group, the venous blood was sampled before and after the first, third and the completion of the treatment course respectively, the venous blood was taken at each corresponding time point in the control group. After centrifugation of the blood at 10 000 rounds per minute, the RBC membrane was separated and then the activities of K^＋-Na^＋-ATPase and Ca2^＋-Mg2^＋-ATPase were detected by means of phosphorus determination.③ The nerve function was scored before and after treatment in both groups with European stroke scale, which included 13 items, the total score was 0-100 points, the higher the score, the better the nerve function. MAIN OUTCOME MEASURES ：①Score of European stroke scale before and after treatment in both groups.② Comparison of the activities of K^＋-Na^＋-ATPase and Ca2^＋-Mg2^＋-ATPase on RBC membrane between the two groups before treatment and after the first, third and the completion of the treatment. RESULTS： All the 58 patients with cerebral infarction were involved in the analysis of results.① The score of European stroke scale had no obvious difference between the two groups [（49.31±11.48）, （50.58±12.63）, P 〉 0.05], and it was obviously higher in the UBIO treated group than in the control group after treatment [84.66±13.75）, （77.05±11.17）, P 〈 0.05].②The activity of K^＋-Na^＋-ATPase on RBC membrane in the UBIO treated group was significantly increased after the first and third treatment as compared with before treatment [（31.56±19.25）, （27.64±15.83）, （17.67±13.83）, P 〈 0.01], it was still higher after the completion of the treatment than before treatment without obvious difference [（20.86±14.53）, P 〉 0.05]. After the first and third treatment, it was obviously higher in the UBIO treated group than in the control group [19.31±11.88）, （17.44±10.42）, P 〈 0.01]. ③ In the UBIO treated group, Ca2^＋-Mg2^＋-ATPase activity on RBC membrane significantly increased after the first treatment and remained higher than the pre-treatment level throughout the treatment [（27.49±14.72）, （17.41±4.82）, P 〈 0.01]. The activity of Ca2^＋-Mg2^＋-ATPase on RBC membrane was markedly higher in the UBIO treated group than in the control group after after the first, third and the completion of treatment respectively [（24.83±12.88）, （17.70±5.69）; （28.08±13.44）, （16.32±5.29）; （17.42±6.04）, P〈 0.05-0.01]. CONCLUSION： The effect of UBIO treatment against acute cerebral infarction may be mediated by the increased K^＋-Na^＋ ATPase and Ca2^＋-Mg2^＋-ATPase activities on RBC membrane, which enhances the RBC transformation ability so as to lower RBC aggregation and correct high blood viscosity.
