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SIGNIFICANCE TEST FOR EMPIRICAL ORTHOGONAL FUNCTION (EOF) ANALYSIS OF METEOROLOGICAL AND OCEANIC DATA 被引量:2
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作者 李晓峰 Pietrafesa +2 位作者 L.J 蓝淑芳 谢立安 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2000年第1期10-17,共8页
A Monte Carlo experiment was done to create a statistically significant test table for selecting EOF modes whose signals are above the noise level. Numerical analysis showed that it is feasible to choose a shorter dat... A Monte Carlo experiment was done to create a statistically significant test table for selecting EOF modes whose signals are above the noise level. Numerical analysis showed that it is feasible to choose a shorter data set between temporal and spatial dimensions for conducting an EOF analysis, and thus simplify calculation of the covariance matrix and solution of its eigenvalues and eigenvectors. The experiment showed that the dominant EOF modes remained the same. This approach is more computationally efficient, reducing both computing time and computer memory requirement, while still retaining the dominant signal. 展开更多
关键词 eof analysis significance test TABLE
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Transient analysis of functionally graded curved shells using a nonuniform shape parameter integrated radial basis function approach
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作者 Vay Siu Lo Andrzej Katunin Thien Tich Truong 《Theoretical & Applied Mechanics Letters》 2025年第3期296-308,共13页
In this study,an improved integrated radial basis function with nonuniform shape parameter is introduced.The proposed shape parameter varies in each support domain and is defined byθ=1/d_(max),where d_(max)is the max... In this study,an improved integrated radial basis function with nonuniform shape parameter is introduced.The proposed shape parameter varies in each support domain and is defined byθ=1/d_(max),where d_(max)is the maximum distance of any pair of nodes in the support domain.The proposed method is verified and shows good performance.The results are stable and accurate with any number of nodes and an arbitrary nodal distribution.Notably,the support domain should be large enough to obtain accurate results.This method is then applied for transient analysis of curved shell structures made from functionally graded materials with complex geometries.Through several numerical examples,the accuracy of the proposed approach is demonstrated and discussed.Additionally,the influence of various factors on the dynamic behavior of the structures,including the power-law index,different materials,loading conditions,and geometrical parameters of the structures,was investigated. 展开更多
关键词 Integrated radial basis function Shape parameter functionally graded material Curved shell Transient analysis
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Mutual Relationship between Grip Strength and Cognitive Function in Chinese Middle-Aged and Elderly People over 10 Years:A Cross-Lagged Panel Analysis
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作者 Jiaqi Wang Ye Ruan +5 位作者 Yanfei Guo Shuangyuan Sun Anli Jiang Yujun Dong Yan Shi Fan Wu 《Biomedical and Environmental Sciences》 2025年第10期1308-1313,共6页
In 2019,China had over 13.14 million dementia cases,with incidence rates of(56.47–207.08)/100,000[1].Early cognitive impairment—a key dementia symptom—reduces quality of life,increases care dependence,and lowers su... In 2019,China had over 13.14 million dementia cases,with incidence rates of(56.47–207.08)/100,000[1].Early cognitive impairment—a key dementia symptom—reduces quality of life,increases care dependence,and lowers survival in older adults[2].A decline in physical function can also be observed in older adults with increasing age.Grip strength has been shown to be a marker of overall physiological function in older adults. 展开更多
关键词 decline physical function physiological function cognitive function cognitive impairment Chinese middle aged elderly grip strength cross lagged panel analysis DEMENTIA
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From Wave Energy to Electricity:Functional Design and Performance Analysis of Triboelectric Nanogenerators
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作者 Ying Lou Mengfan Li +2 位作者 Aifang Yu Junyi Zhai Zhong Lin Wang 《Nano-Micro Letters》 2025年第12期33-73,共41页
Triboelectric nanogenerators(TENGs)offer a selfsustaining power solution for marine regions abundant in resources but constrained by energy availability.Since their pioneering use in wave energy harvesting in 2014,nea... Triboelectric nanogenerators(TENGs)offer a selfsustaining power solution for marine regions abundant in resources but constrained by energy availability.Since their pioneering use in wave energy harvesting in 2014,nearly a decade of advancements has yielded nearly thousands of research articles in this domain.Researchers have developed various TENG device structures with diverse functionalities to facilitate their commercial deployment.Nonetheless,there is a gap in comprehensive summaries and performance evaluations of TENG structural designs.This paper delineates six innovative structural designs,focusing on enhancing internal device output and adapting to external environments:high space utilization,hybrid generator,mechanical gain,broadband response,multi-directional operation,and hybrid energy-harvesting systems.We summarize the prevailing trends in device structure design identified by the research community.Furthermore,we conduct a meticulous comparison of the electrical performance of these devices under motorized,simulated wave,and real marine conditions,while also assessing their sustainability in terms of device durability and mechanical robustness.In conclusion,the paper outlines future research avenues and discusses the obstacles encountered in the TENG field.This review aims to offer valuable perspectives for ongoing research and to advance the progress and application of TENG technology. 展开更多
关键词 Triboelectric nanogenerator functional design Blue energy Electrical performance Sustainability analysis
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Correlation of anxiety and depression with ankle function in chronic ankle instability patients and analysis of risk factors
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作者 Zu-Po Yu 《World Journal of Psychiatry》 2025年第7期83-90,共8页
BACKGROUND Psychological comorbidities,such as anxiety and depression,in patients with chronic ankle instability(CAI)may impede ankle function improvement,although the precise nature of this association warrants furth... BACKGROUND Psychological comorbidities,such as anxiety and depression,in patients with chronic ankle instability(CAI)may impede ankle function improvement,although the precise nature of this association warrants further investigation.AIM To analyze the correlation of anxiety and depression with ankle function in patients with CAI and discussing the risk factors.METHODS This study included 116 patients with CAI,who were admitted to our hospital from July 2022 to July 2024.Anxiety and depression states of patients were assessed with the self-rating anxiety scale(SAS)and self-rating depression scale(SDS),respectively,and their ankle joint function was assessed with the anklehindfoot function score of the American Orthopedic Foot and Ankle Society.Further,the ankle function of patients with CAI with different anxiety and depression states was discussed.Furthermore,the Pearson correlation coefficient was used to analyze the correlation of anxiety and depression with ankle joint function in such patients.Univariate and multivariate analyses were conducted to investigate the factors affecting ankle joint function in patients with CAI.RESULTS Among the 116 patients with CAI,97,13,5,and 1 cases demonstrated none,mild,moderate,and severe anxiety,whereas 95,15,6,and 0 cases showed none,mild,moderate,and severe depression,respectively.The average ankle joint function score was 74.82±6.93 points.The ankle joint function in patients with CAI presented a significant downward tendency as the degree of anxiety and depression increased.Correlation analysis revealed that both the SAS and SDS scores of patients with CAI were significantly negatively correlated with the ankle joint function score.Univariate and multivariate analyses indicated that the risk factors affecting patients’ankle joint function included early functional rehabilitation,visual analog scale,and SDS.CONCLUSION A substantial number of patients with CAI suffer from anxiety and depression,and these negative emotions,to a certain extent,harm the smooth rehabilitation of ankle joint function. 展开更多
关键词 Chronic ankle instability Anxiety and depression Ankle function Correlation analysis Risk factors
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Identification of Rice Leaf Width Gene FLW11 Through Genome-Wide Association Study and Functional Analysis
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作者 YANG Yulu ZHANG Yanfang +14 位作者 LIU Xiong ZHANG Lihua HUANG Jingfen SHEN Lixing ZHAO Huibo SHEN Lan ZHANG Qiang ZHU Li HU Jiang REN Deyong GAO Zhenyu DONG Guojun QIAO Weihua QIAN Qian ZHANG Guangheng 《Rice science》 2025年第6期756-760,I0018-I0023,共11页
The width of rice leaves determines the size of the photosynthetic area.Optimizing rice leaf width can improve the photosynthetic rate,thereby increasing rice yield.In this study,a genome-wide association study(GWAS)w... The width of rice leaves determines the size of the photosynthetic area.Optimizing rice leaf width can improve the photosynthetic rate,thereby increasing rice yield.In this study,a genome-wide association study(GWAS)was conducted by 225 rice germplasm resources to explore the genetic basis of rice flag leaf width(FLW).We identified nine QTLs associated with FLW(qFLWs),with phenotypic contribution rates ranging from 3.17%to 14.37%.Near-isogenic lines(NILs)were developed for fine-mapping of qFLW11,and the function of FLW11 was further verified.We narrowed down q FLW11 to an 87-kb interval,which contains five genes. 展开更多
关键词 functional analysis genome wide association study rice leaf width flag leaf width rice germplasm resources qtl photosynthetic rate phenotypic contribution rates
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A bibliometric analysis of publication trends in strabismus over the past 30y
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作者 Yi-Han Zhang Ying Guo +1 位作者 Shu-Jie Zhang Chen Zhao 《International Journal of Ophthalmology(English edition)》 2026年第1期149-159,共11页
AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 ... AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation. 展开更多
关键词 bibliometric analysis STRABISMUS intermittent exotropia strabismus surgery functional magnetic resonance imaging research trends
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Analysis of the Protein Structure and Function of HpaG_(Xoo) 被引量:2
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作者 任秀艳 冯雪 +1 位作者 侯志敏 张倩倩 《Agricultural Science & Technology》 CAS 2010年第2期12-14,75,共4页
[Objective] The study was to analyze the structure and function of HpaGXoo and the relationship between the two.[Method] Some related bioinformatics analysis software on internet such as NPSA,Swiss-Model,SAPS and Inte... [Objective] The study was to analyze the structure and function of HpaGXoo and the relationship between the two.[Method] Some related bioinformatics analysis software on internet such as NPSA,Swiss-Model,SAPS and InterPro Scan were adopted to analyze the structure and predict its function.[Result] HpaGXoo consists of 139 amino acids,and has many alpha-helical and coiled structure,no signal peptide on N-terminal and no transmembrane structure.It locates in bacterial cytoplasm.[Conclusion] The study will lay ... 展开更多
关键词 HpaGXoo BIOINFORMATICS Structure analysis function prediction
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Analysis of Emergy Structure,Function and Efficiency of Agro-ecosystem in Hunan Province 被引量:1
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作者 朱玉林 李明杰 +2 位作者 侯茂章 龙雨孜 王茂溪 《Agricultural Science & Technology》 CAS 2013年第1期186-192,共7页
[Objective] The aim was to explore function and efficiency of emergy input/ output of Hunan agricultural ecosystem to reveal relationship of human being with natural resources and environment. [Method] Emergy structur... [Objective] The aim was to explore function and efficiency of emergy input/ output of Hunan agricultural ecosystem to reveal relationship of human being with natural resources and environment. [Method] Emergy structure, function and efficien- cy of Hunan agricultural ecosystem were analyzed based on input/output data in Hunan Province in 2009 as per emergy theory. [Result] The structure characters of agricultural ecosystem were as follows: Hunan is characterized with traditional agri- culture, depending greatly on both human and animal labor. For industrial accessory emergy, chemical fertilizers make most contribution to the system, and agricultural mechanization is not satisfied. Furthermore, renewable ratio of industrial accessory emergy is lower, and development and potential of green energy is promising. In addition, prices of the products are lower, without consideration of contribution made by natural resources and environment. It also suggested that Hunan agricultural chain is short and added value of products is not high. In general, emergy output of farming and animal husbandry dominates and the prices are lower than those of forestry and fishery. The function of the system was as follows: With lower environ- mental load ratio, the system is overloaded by population and the index of sustain- able development was 5.96, suggesting that the system enjoys vitality and potential, but the economy is undeveloped and the pressure from natural resources and envi- ronment is not high. The emergy output ratio was a little lower than national level in 2009, suggesting Hunan agricultural production is extensive. [Conclusion] The re- search indicated that rapid increase of population should be controlled; surplus labor should be transferred; agricultural structure and products structure should be further adjusted; agricultural technology should be further developed; agdcultural mechaniza- tion and modernization should be improved. 展开更多
关键词 Energy analysis STRUCTURE function EFFICIENCY Agriculture of Hunan Province introduction
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Stability analysis for affine fuzzy system based on fuzzy Lyapunov functions
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作者 柳善建 沈炯 +1 位作者 刘西陲 李益国 《Journal of Southeast University(English Edition)》 EI CAS 2011年第3期295-299,共5页
An analysis method based on the fuzzy Lyapunov functions is presented to analyze the stability of the continuous affine fuzzy systems. First, a method is introduced to deal with the consequent part of the fuzzy local ... An analysis method based on the fuzzy Lyapunov functions is presented to analyze the stability of the continuous affine fuzzy systems. First, a method is introduced to deal with the consequent part of the fuzzy local model. Thus, the stability analysis method of the homogeneous fuzzy system can be used for reference. Stability conditions are derived in terms of linear matrix inequalities based on the fuzzy Lyapunov functions and the modified common Lyapunov functions, respectively. The results demonstrate that the stability result based on the fuzzy Lyapunov functions is less conservative than that based on the modified common Lyapunov functions via numerical examples. Compared with the method which does not expand the consequent part, the proposed method is simpler but its feasible region is reduced. Finally, in order to expand the application of the fuzzy Lyapunov functions, the piecewise fuzzy Lyapunov function is proposed, which can be used to analyze the stability for triangular or trapezoidal membership functions and obtain the stability conditions. A numerical example validates the effectiveness of the proposed approach. 展开更多
关键词 affine fuzzy system stability analysis linear matrix inequalities fuzzy Lyapunov function
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Molecular evolutionary analysis of gene families encoding DNA recombination and repair proteins and histone demethylases,and their functional implications
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作者 马红 《生物物理学报》 CAS CSCD 北大核心 2009年第S1期5-5,共1页
Many eukaryotic genes are members of multi-gene families due to gene duplications, which generate new copies that allow functional divergence. However, the relationship between
关键词 GENE Molecular evolutionary analysis of gene families encoding DNA recombination and repair proteins and histone demethylases and their functional implications DNA
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Translation Analysis from Functional Linguistics Perspective
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作者 褚亮 《海外英语》 2011年第9X期202-203,205,共3页
As a branch of linguistics,Functional Grammar plays an important role in translation analysis.From the perspective of patterns of progression and cohesion,a text and its translation from TEM8 examination is studied as... As a branch of linguistics,Functional Grammar plays an important role in translation analysis.From the perspective of patterns of progression and cohesion,a text and its translation from TEM8 examination is studied as an example to get some general rules,and thus,a new approach of translation analysis is offered. 展开更多
关键词 TRANSLATION analysis functional LINGUISTICS THEMATIC PROGRESSION COHESION application
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Study on the Temporal and Spatial Distribution Characteristic of Acid Rain in Guangxi Based on EOF Analysis 被引量:1
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作者 孙崇智 梁骏 +1 位作者 王超球 郑凤琴 《Meteorological and Environmental Research》 CAS 2010年第11期56-58,63,共4页
Based on acid rain data from ten monitoring sites in Guangxi from 2003 to 2009,the temporal and spatial distribution characteristic of acid rain in Guangxi were analyzed by means of empirical orthogonal function resol... Based on acid rain data from ten monitoring sites in Guangxi from 2003 to 2009,the temporal and spatial distribution characteristic of acid rain in Guangxi were analyzed by means of empirical orthogonal function resolution(EOF).The results showed that there was fluctuating change of acid rain frequency in Guangxi,and acid rain pollution became severer in 2004-2008;acid rain frequency changed conformably in the whole region and it was obviously higher in eastern and northwestern Guangxi,while acid rain pollution became severe in western Guangxi;acid rain frequency varied out of phase between northeastern and southwestern Guangxi in an individual year. 展开更多
关键词 Acid rain Temporal and spatial distribution characteristic eof analysis China
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基于REOF的不同量级降雨侵蚀力时空变化——以重庆市为例 被引量:1
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作者 靳军英 王林 +1 位作者 金铁生 张卫华 《西南大学学报(自然科学版)》 CAS 北大核心 2025年第1期163-177,共15页
研究重庆市不同地理分区内各量级降雨侵蚀力的时空变化特征,为该地区进行更加精准的区域性水土流失防治工作提供理论依据。选取1981-2020年重庆市31个站点逐日降雨数据,利用旋转经验正交函数(Rotated Empirical Orthogonal Function,RE... 研究重庆市不同地理分区内各量级降雨侵蚀力的时空变化特征,为该地区进行更加精准的区域性水土流失防治工作提供理论依据。选取1981-2020年重庆市31个站点逐日降雨数据,利用旋转经验正交函数(Rotated Empirical Orthogonal Function,REOF)对降雨侵蚀力进行地理分区,并结合R/S、5年滑动平均、Mann-Kendall检验等方法,分析各分区不同量级降雨侵蚀力时空变化。结果表明:①重庆市降雨侵蚀力可分为6个地理区域(Ⅰ-Ⅵ区);②重庆市多年平均降雨侵蚀力为5784.04 MJ·mm/(hm^(2)·h·a),不同降雨侵蚀力从大到小依次为:大雨、暴雨、中雨、大暴雨;③大雨侵蚀力在Ⅰ-Ⅲ区和Ⅴ-Ⅵ区占主导优势,暴雨侵蚀力在Ⅳ区占主导优势。各分区中,中雨、大雨及暴雨侵蚀力主要集中在5-9月,大暴雨侵蚀力集中在6-8月;④各区不同量级降雨侵蚀力年际变化从小到大依次为:中雨、大雨、暴雨、大暴雨;同一量级降雨侵蚀力的整体变化趋势均不显著;Hurst指数表明,中雨侵蚀力在Ⅰ和Ⅴ区、大雨侵蚀力在Ⅱ和Ⅴ区、大暴雨侵蚀力在Ⅰ和Ⅲ区呈强持续上升趋势;⑤中雨、大雨及大暴雨侵蚀力在渝东南、渝东北占主导优势,暴雨侵蚀力在渝西以及重庆中部占主导优势,且Ⅰ区酉阳和秀山、Ⅱ区开州、Ⅲ区北碚和铜梁、Ⅳ区璧山和永川、Ⅴ区巫溪和云阳及Ⅵ区忠县是不同量级降雨侵蚀力的高峰中心。通过对重庆各分区不同量级降雨侵蚀力的分析,明确了可能引起土壤侵蚀的主要雨型、高发时期和潜在风险较高的地区,可为区域水土流失动态监测和水土保持措施的合理制定提供参考。 展开更多
关键词 降雨侵蚀力 时空变化 旋转经验正交分解法 MK非参数趋势检验 R/S分析法
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Semen analysis in 21st century medicine: the need for sperm function testing 被引量:27
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作者 Dolores J. Lamb 《Asian Journal of Andrology》 SCIE CAS CSCD 2010年第1期64-70,共7页
Sperm function testing, once commonly performed for the infertile couple before employing assisted reproductive technology (ART), has fallen out of favour in many reproductive medicine centers throughout the world. ... Sperm function testing, once commonly performed for the infertile couple before employing assisted reproductive technology (ART), has fallen out of favour in many reproductive medicine centers throughout the world. Indeed, the most recent addition of the 'World Health Organisation (WHO) Laboratory Manual for the Examination and Processing of Hu- man Semen' now groups many of these procedures into a section termed Research Procedures. In large part, this reflects the current clinical practice of bypassing the in-depth evaluation of the male partner, while assuming that if a spermatozoon can be found for intracytoplasmic sperm injection (ICSI), it must be a healthy cell capable of achieving fertilization. Never- theless, sperm function testing can provide valuable clinical insights into defects causing male infertility. Admittedly, in some cases, functional sperm deficiencies can be overcome using an ART. In other cases, couples will be empowered by the knowledge of the cause of their infertility, and for some couples, perhaps even the likelihood of ICSI success (relative to the spermatozoa). The knowledge allows them to make truly informed reproductive decisions, including (perhaps) the de- cision to seek donor insemination, to adopt or to remain childless. Knowledge of the cause of their infertility may provide closure for couples and a sense of confidence regarding their choice of reproductive treatment. 展开更多
关键词 semen analysis sperm function tests
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Free vibration analysis of functionally graded laminated sandwich cylindrical shells integrated with piezoelectric layer 被引量:7
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作者 M.AREFI R.KARROUBI M.IRANI-RAHAGHI 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2016年第7期821-834,共14页
An analytical method for the three-dimensional vibration analysis of a functionally graded cylindrical shell integrated by two thin functionally graded piezoelectric (FGP) layers is presented. The first-order shear ... An analytical method for the three-dimensional vibration analysis of a functionally graded cylindrical shell integrated by two thin functionally graded piezoelectric (FGP) layers is presented. The first-order shear deformation theory is used to model the electromechanical system. Nonlinear equations of motion are derived by considering the von Karman nonlinear strain-displacement relations using Hamilton's principle. The piezoelectric layers on the inner and outer surfaces of the core can be considered as a sensor and an actuator for controlling characteristic vibration of the system. The equations of motion are derived as partial differential equations and then discretized by the Navier method. Numerical simulation is performed to investigate the effect of different para- meters of material and geometry on characteristic vibration of the cylinder. The results of this study show that the natural frequency of the system decreases by increasing the non-homogeneous index of FGP layers and decreases by increasing the non-homogeneous index of the functionally graded core. Furthermore, it is concluded that by increasing the ratio of core thickness to cylinder length, the natural frequencies of the cylinder increase considerably. 展开更多
关键词 free vibration nonlinear analysis frequency analysis cylindrical shell functionally graded material (FGM) functionally graded piezoelectric material (FGPM)
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Functions of Uni- and Multi-citations: Implications for Weighted Citation Analysis 被引量:7
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作者 Dangzhi Zhao Alicia Cappello Lucinda Johnston 《Journal of Data and Information Science》 CSCD 2017年第1期51-69,共19页
Purpose: (1) To test basic assumptions underlying frequency-weighted citation analysis: (a) Uni-citations correspond to citations that are nonessential to the citing papers; (b) The influence of a cited paper ... Purpose: (1) To test basic assumptions underlying frequency-weighted citation analysis: (a) Uni-citations correspond to citations that are nonessential to the citing papers; (b) The influence of a cited paper on the citing paper increases with the frequency with which it is cited in the citing paper. (2) To explore the degree to which citation location may be used to help identify nonessential citations. Design/methodology/approach: Each of the in-text citations in all research articles published in Issue 1 of the Journal of the Association for Information Science and Technology (JASIST) 2016 was manually classified into one of these five categories: Applied, Contrastive, Supportive, Reviewed, and Perfunctory. The distributions of citations at different in-text frequencies and in different locations in the text by these functions were analyzed. Findings: Filtering out nonessential citations before assigning weight is important for frequency-weighted citation analysis. For this purpose, removing citations by location is more effective than re-citation analysis that simply removes uni-citations. Removing all citation occurrences in the Background and Literature Review sections and uni-citations in the Introduction section appears to provide a good balance between filtration and error rates. Research limitations: This case study suffers from the limitation of scalability and generalizability. We took careful measures to reduce the impact of other limitations of the data collection approach used. Relying on the researcher's judgment to attribute citation functions, this approach is unobtrusive but speculative, and can suffer from a low degree of confidence, thus creating reliability concerns. Practical implications: Weighted citation analysis promises to improve citation analysis for research evaluation, knowledge network analysis, knowledge representation, and information retrieval. The present study showed the importance of filtering out nonessential citations before assigning weight in a weighted citation analysis, which may be a significant step forward to realizing these promises. Originality/value: Weighted citation analysis has long been proposed as a theoretical solution to the problem of citation analysis that treats all citations equally, and has attracted increasing research interest in recent years. The present study showed, for the first time, the importance of filtering out nonessential citations in weighted citation analysis, pointing research in this area in a new direction. 展开更多
关键词 Weighted citation analysis Citation function Research evaluation In-text citation analysis Re-citation analysis
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GOMA:functional enrichment analysis tool based on GO modules 被引量:5
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作者 Qiang Huang Ling-Yun Wu +1 位作者 Yong Wang Xiang-Sun Zhang 《Chinese Journal of Cancer》 SCIE CAS CSCD 2013年第4期195-204,共10页
Analyzing the function of gene sets is a critical step in interpreting the results of high-throughput experiments in systems biology. A variety of enrichment analysis tools have been developed in recent years, but mos... Analyzing the function of gene sets is a critical step in interpreting the results of high-throughput experiments in systems biology. A variety of enrichment analysis tools have been developed in recent years, but most output a long list of significantly enriched terms that are often redundant, making it difficult to extract the most meaningful functions. In this paper, we present GOMA, a novel enrichment analysis method based on the new concept of enriched functional Gene Ontology (GO) modules. With this method, we systematically revealed functional GO modules, i.e., groups of functionally similar GO terms, via an optimization model and then ranked them by enrichment scores. Our new method simplifies enrichment analysis results by reducing redundancy, thereby preventing inconsistent enrichment results among functionally similar terms and providing more biologically meaningful results. 展开更多
关键词 GO ENRICHMENT analysis modules functionAL redundancy network RELATIONSHIPS
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Multi-factor analysis of initial poor graft function after orthotopic liver transplantation 被引量:12
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作者 Chen, Hao Peng, Cheng-Hong +5 位作者 Shen, Bai-Yong Deng, Xia-Xing Shen, Chuan Xie, Jun-Jie Dong, Wei Li, Hong-Wei 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2007年第2期141-146,共6页
BACKGROUND: In the early period of orthotopic liver transplantation (OLT), initial poor graft function (IPGF) is one of the complications which leads to primary graft non-function (PGNF) in serious cases. This study s... BACKGROUND: In the early period of orthotopic liver transplantation (OLT), initial poor graft function (IPGF) is one of the complications which leads to primary graft non-function (PGNF) in serious cases. This study set out to establish the clinical risk factors resulting in IPGF after OLT. METHODS: Eighty cases of OLT were analyzed. The IPGF group consisted of patients with alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) above 1500 IU/L within 72 hours after OLT, while those in the non-IPGF group had values below 1500 IU/L. Recipient-associated factors before OLT analyzed were age, sex, primary liver disease and Child-Pugh classification; factors analyzed within the peri-operative period were non-heart beating time (NHBT), cold ischemia time (CIT), rewarming ischemic time (RWIT), liver biopsy at the end of cold ischemia; and factors analyzed within 72 hours after OLT were ALT and/or AST values. A logistic regression model was applied to filter the possible factors resulting in IPGF. RESULTS: Donor NHBT, CIT and RWIT were significantly longer in the IPGF group than in the non-IPGF group; in the logistic regression model, NHBT was the risk factor leading to IPGF (P < 0.05), while CIT and RWIT were possible risk factors. In one case in the IPGF group, PGNF appeared with moderate hepatic steatosis. CONCLUSIONS: Longer NHBT is an important risk factor leading to IPGF, while serious steatosis in the donor liver, CIT and RWIT are potential risk factors. 展开更多
关键词 orthotopic liver transplantation poor liver function multi-factor analysis
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Semen analysis and sperm function testing 被引量:11
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作者 Daniel R Franken Sergio Oehninger 《Asian Journal of Andrology》 SCIE CAS CSCD 2012年第1期6-13,174,共9页
Despite controversy regarding the clinical value of semen analysis, male fertility investigation still relies on a standardized analysis of the semen parameters. This is especially true for infertility clinics in both... Despite controversy regarding the clinical value of semen analysis, male fertility investigation still relies on a standardized analysis of the semen parameters. This is especially true for infertility clinics in both developing and developed countries. Other optional tests or sophisticated technologies have not been widely applied. The current review addresses important changes in the analysis of semen as described in the new World Health Organization (WHO) manual for semen analysis. The most important change in the manual is the use of evidence-based publications as references to determine cutoff values for normality. Apart from the above mentioned changes, the initial evaluation and handling methods remain, in most instances, the same as in previous editions. Furthermore, the review evaluates the importance of quality control in andrology with emphasis on the evaluation of sperm morphology. WHO sperm morphology training programmes for Sub-Saharan countries were initiated at Tygerberg Hospital in 1995. The external qualitY control programme has ensured that the majority of participants have maintained their morphological reading skills acquired during initial training. This review reports on current sperm functional tests, such as the induced acrosome reaction, and sperm-zona pellucida binding assays, as well as the impact of sperm quality in terms of DNA integrity, and the relationship of sperm function tests to sperm morphology. 展开更多
关键词 male infertility quality assurance semen analysis spermatozoa sperm concentration sperm function sperm morphology sperm motility
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