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Generalized Gr?tzsch ring function and generalized elliptic integrals 被引量:1
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作者 MA Xiao-yan QIU Song-liang TU Guo-yan 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2016年第4期458-468,共11页
Abstract. In this paper, we study the quotient of hypergeometric functions μα (r) in the theory of Ramanujan's generalized modular equation for α ∈(0, 1/2]. Several new inequalities are given for this and rela... Abstract. In this paper, we study the quotient of hypergeometric functions μα (r) in the theory of Ramanujan's generalized modular equation for α ∈(0, 1/2]. Several new inequalities are given for this and related functions. Our main results complement and generalize some known results in the literature. 展开更多
关键词 Gaussian hypergeometric function generalized GrStzsch ring function generalized elliptic func-tion.
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Effects of individualized therapeutic porgram with heatreinforcing needling in combination with Bobath therapy on gross motor dysfunction in children with cerebral palsy:a randomized controlled trial 被引量:8
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作者 张宁霞 王翔宇 +2 位作者 李匀博 刘桂珍 张红英 《World Journal of Acupuncture-Moxibustion》 2014年第1期26-31,共6页
Objective To explore the effect of heat-reinforcing acupuncture combined with Bobath rehabilita on training for the gross motor func on measurement(GMFM) in children with cerebral palsy. Methods Sixty cases of cereb... Objective To explore the effect of heat-reinforcing acupuncture combined with Bobath rehabilita on training for the gross motor func on measurement(GMFM) in children with cerebral palsy. Methods Sixty cases of cerebral palsy were randomized into a heat-reinforcing acupuncture combined with rehabilitation training group(group A) and a rehabilitation group(group B),30 cases in each group. Rehabilitation training was applied in group B and heat-reinforcing acupuncture was added in group A. Jiāji(夹脊 EX-B 2),Jiānyú(肩髃 LI 15),Qūchí(曲池 LI 11),Hégi(合谷 LI 4),Yánglíngquán(阳陵泉 GB 34),Yīnlíngquán(阴陵泉 SP 9),Xuánzhōng(悬钟 GB 39),Zúsānli(足三里 ST 36),Sānyīnjiāo(三阴交 SP 6),Chéngshān(承山 BL 57),Tài chōng(太冲 LR 3),Tàixī(太溪 KI 3) and Shénmén(神门 HT 4) were chosen in group A and the heat-reinforcing acupuncture was applied once a day. For scalp acupuncture,Biihuì(百会 GV 20),Sìshéncōng(四神聪 EX-HN 1),Zhìsānzhēn(智三针),Nǎosānzhēn(脑三针),Nièsānzhēn(颞三针) and motor area(运动区) were punctured without any manipulation,once every other day,3 months as a treatment course and 2 courses were needed. GMFM were selected to assess the children with cerebral palsy before treatment,a er 3 months treatment and a er 6 months treatment. Results The total eff ec ve rate in group A was 70.00%(21/30),which is superior to that of 60.00%(24/30) in group B(P0.05). In group A,the GMFM scores of decubitus position and turn-over of body,creeping and kneeling,sitting,standing,walking,running and jumping after6 months treatment were significantly improved compared with that before treatment and after 3 months treatment(all P0.05). In group B,above indices a er 6 months treatment were significantly improved compared with those before treatment,the standing score after 6 months treatment was significantly improved compared with that a er 3 months treatment(P0.05); the GMFM scores of creeping,kneeling,sitting,standing,walking,running and jumping after 6 months treatment in group A were more significantly improved than that in group B(all P0.05). Conclusion The heat-reinforcing acupuncture combined with Bobath rehabilita on training has a be er eff ect than rehabilitation training on the GMFM scores of creeping and kneeling,si ng,standing,walking,running and jumping of children with cerebral palsy. It can be shown that the combination of heat-reinforcing acupuncture and Bobath rehabilita on training can improve the gross motor func on of children with cerebral palsy. 展开更多
关键词 child cerebral palsy Bobath therapy heat-reinforcing needling gross motor func on measurement(GMFM)
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原发性脑出血患者功能结果预测—FUNC评分的临床实用价值
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作者 梁宪宏 张维明 马志国 《航空航天医学杂志》 2012年第9期1061-1062,共2页
目的:探讨FUNC量表预测原发性脑内出血的功能性结局的临床实用价值。方法:采用前瞻性和回顾性相结合的方法对一定时期内的脑出血患者进行临床观察和病例回调,按照量表中的各项要求,对患者在脑出血急性期的各项临床表现进行评分,然后定... 目的:探讨FUNC量表预测原发性脑内出血的功能性结局的临床实用价值。方法:采用前瞻性和回顾性相结合的方法对一定时期内的脑出血患者进行临床观察和病例回调,按照量表中的各项要求,对患者在脑出血急性期的各项临床表现进行评分,然后定期电话回访,记录患者在90 d时的生存情况,以此判断FUNC量表是否适用于我国急性脑出血患者的预后预测。结果:FUNC量表对原发性脑出血患者的90 d末的生存情况预测具有统计学意义。结论:FUNC量表对我国原发性脑出血患者的预后有很好的预测功能。 展开更多
关键词 func量表 准确率 脑出血
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Command functions of open loop galvanometer scanners with optimized duty cycles
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作者 V.F.Duma 《Theoretical & Applied Mechanics Letters》 CAS 2012年第4期34-39,共6页
The paper approaches the problem of the command functions of galvanometer-based scanners (GS) that are necessary to produce the linear plus parabolic scanning function of the GS, which we have proved previously to p... The paper approaches the problem of the command functions of galvanometer-based scanners (GS) that are necessary to produce the linear plus parabolic scanning function of the GS, which we have proved previously to produce the highest possible duty cycle (i.e., time efficiency) of the device. We have completed this theoretical aspect (which contradicted what has been stated previously in the literature, where it has been considered that the linear plus sinusoidal scanning function was the best) with the experimental study of the most used scanning functions of the GSs (sawtooth, sinusoidal and triangular), with applications in biomedical imaging, in particular in optical coherence tomography, demonstrating that the triangular function is always the best one to be applied, from both an optical and a mechanical point of view. In the present study the input voltage/command function which should be applied to the GS to produce the desired triangular scanning function (with controlled non-linearity for the fastest possible stop-and-turn portions) was determined analytically, in relationship with the active torque that drives the device. This command function is analyzed with regard to the specific, respectively required parameters of the GS: natural frequency and damping factor, respectively scan speed and amplitude. The modeling in an open loop control structure of the GS is finally discussed as a trade-off between using the highest possible duty cycle and minimizing the maximum peaks of the input voltage. 展开更多
关键词 scanners galvanometer scanner optomechatronics scanning functions command func-tions duty cycle driving torque
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Modulatory Effects of Compound Polysaccharide Erweikang on the Immune Function o f Mice 被引量:2
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作者 杜光 马宝瑕 +1 位作者 张锐 孙明辉 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2002年第3期221-223,共3页
In order to study the modulatory effects of compound polysaccharide Erweikang on the immune function of the immunosuppressive mice, the positive immune modulati on of Erweikang at different doses and different time p... In order to study the modulatory effects of compound polysaccharide Erweikang on the immune function of the immunosuppressive mice, the positive immune modulati on of Erweikang at different doses and different time points was compared when n ormal saline and cyclophosphamide served as controls. The results showed that di fferent doses of Erweikang could effectively reverse the decreased induction lev els of NK, IL 2, γ IFN and the contents of TNF and IgG of the immunosu ppressive mice after administration of Erweikang for 7 to 14 days. It was sugges ted that compound polysaccharide Erweikang presents positive immune modulation i n dose and time dependent manners. 展开更多
关键词 compound polysaccharide Erweikang immune func tion mice immunosuppressive
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Early rehabilitation improves neurofunctional outcome after surgery in children with spinal tumors 被引量:4
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作者 Nezire Kose Ozge Muezzinoglu +3 位作者 Sevil Bilgin Sevilay Karahan Ilkay Is kay Burcak Bilginer 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第2期129-134,共6页
To investigate the effect of early rehabilitation on neurofunctional outcome after surgery in chil- dren with spinal tumors, this study reviewed the medical charts and radiographic records of 70 pediatric patients (1... To investigate the effect of early rehabilitation on neurofunctional outcome after surgery in chil- dren with spinal tumors, this study reviewed the medical charts and radiographic records of 70 pediatric patients (1-17 years old) who received spinal tumor surgical removal. The peddiatric patients received rahabilitation treatment at 4 (range, 2-7) days after surgery for 10 (range, 7-23) days. Results from the Modified McCormick Scale, Functional Independence Measure for Chil- dren, American Spinal Injury Association Impairment Scale and Karnofsky Performance Status Scale demonstrated that the sensory function, motor function and activity of daily living of pedi- atric children who received early rehabilitation were significantly improved. Results also showed that tumor setting and level localization as well as patients's clinical symptoms have no influences on neurofunctional outcomes. 展开更多
关键词 nerve regeneration spinal cord injury spinal cord tumor CHILDREN rehabilitation func-tion SENSE motor retrospective analysis neural regeneration
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A Historic Review on Bilingualism and its Cognitive Function 被引量:1
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作者 卢婷 《海外英语》 2012年第5X期254-255,259,共3页
With global integration going deeper,bilingualism has become a more social issue than a purely linguistic phenomenon.Over seas scholars have been studying in this field for a long time while in China,studies regarding... With global integration going deeper,bilingualism has become a more social issue than a purely linguistic phenomenon.Over seas scholars have been studying in this field for a long time while in China,studies regarding bilingualism are still in its early stages.This pa per provides a historic review on the definition,categorization as well as its cognitive functions.Although it is still a question whether bilin gualism is an advantage or disadvantage to human beings' especially children's cognitive ability,this paper has concluded that early studies showed more negative results while recent research has shifted to a more positive attitude. 展开更多
关键词 BILINGUALISM ADVANTAGE DISADVANTAGE COGNITIVE func
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Beneficial Effects of Delayed Opening the Infarct - related Artery on Late Phase Left Ventricular Function in Acute Anterior Myocardial Infarction
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作者 马礼坤 余华 +5 位作者 黄向阳 褚俊 冯克福 丁晓梅 严激 顾统元 《South China Journal of Cardiology》 CAS 2004年第2期71-74,79,共5页
Objectives To assess the effect of delayed opening the infarct - related artery (IRA) by percutanous coronary intervention (PCI) on the late phase left ventricular function after acute ante- rior myocardial infarction... Objectives To assess the effect of delayed opening the infarct - related artery (IRA) by percutanous coronary intervention (PCI) on the late phase left ventricular function after acute ante- rior myocardial infarction. Methods 64 patients with initial Q - wave anterior myocardial infarction and the infarct - related arteries were total occluded conformed by angiogram at 2 to 14 days after onset were divided into successful PCI group and control group ( not re- ceiving PCI or the IRA not re - opened). 2 - DE was performed at early phase ( about 3 weeks) , 2 and 6 months after onset of AMI respectively to detect the left ventricular function and left ventricular wall motion ab- normality (VWMA). The total congestive heart failure events were recorded during 6 months follow-up. Re- sults VWMA scores, left ventricular ejection frac- tion (LVEF) , left ventricular end - diastolic and end - systolic volume indices ( LVEDVI and LVDSVI) were similar in 2 groups at early phase and 2 months. There were no differences between early phase and 2 months in each group too. VWMA scores and LVEF did not changed at 6 months in each group compared with the early phase and 2 months ( P > 0. 05 ). But LVEDVI and LVESVI were significantly smaller in the successful PCI group than in the control group (P < 0.01, P < 0. 05). The congestive heart failure events were taken place in 19% of patients in control group com- pared with 2% in successful PCI group ( P > 0. 05 ). Conclusions Although the infarct size does not changed, delayed opening the IRA has beneficial effect to the late phase left ventricular dilatation after acuteanterior myocardial infarction. 展开更多
关键词 Acute myocardial infarction Per- cutanous coronary intervention Left ventricular func- tion
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Stability of Boundary Feedback Control Based on Weighted Lyapunov Function in Networks of Open Channels 被引量:4
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作者 CEN Li-Hui XI Yu-Geng 《自动化学报》 EI CSCD 北大核心 2009年第1期97-102,共6页
Lyapunov 功能在串联为二条开的隧道的盒子基于熵的加权的和被构造,它被 Saint-Venant 方程描述。边界反馈控制器的一个班被介绍借助于 Lyapunov 设计途径在平衡点的一位邻居保证本地靠近环的 asymptotic 稳定性。
关键词 Saint-Venant方程 LYAPUNOV函数 渐近稳定度 边界反馈控制
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Asymptotic Stability and Boundedness for Functional Differential Equations
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作者 T.A.Burton (Department of Mathematics,Southern Illinois University,Carbondale,IL 62901-4088,U.S.A)Huang Qichang (Department of Mathematics,Northeast Normal University,Changchun 130024,China) 《Acta Mathematica Sinica,English Series》 SCIE CSCD 1997年第3期363-372,共10页
We study a system(D)x’=F(t,x_t)of functional differential equations,together with a scalar equation(S)x’=-a(t)f(x)+b(t)g(x(t-h))as well as perturbed forms.A Liapunov functional is constructed which has a derivative ... We study a system(D)x’=F(t,x_t)of functional differential equations,together with a scalar equation(S)x’=-a(t)f(x)+b(t)g(x(t-h))as well as perturbed forms.A Liapunov functional is constructed which has a derivative of a nature that has been widely discussed in the literature. On the basis of this example we prove results for(D)on asymptotic stability and equi-boundedness. 展开更多
关键词 functional differential equations Asymptotic stability BOUNDEDNESS Liapunov func-
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Functionalized activated carbon for the adsorptive removal of perchlorate from water solutions 被引量:2
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作者 Rovshan MAHMUDOV Chinglung CHEN Chin-Pao HUANG 《Frontiers of Chemical Science and Engineering》 SCIE EI CAS CSCD 2015年第2期194-208,共15页
Two types of activated carbon, namely, Filtrasorb 400 and Nuchar SA, were functionalized by quaternary ammonium salts (quats), as to enhance perchlorate adsorption. Results showed that the adsorption of quats on Nuc... Two types of activated carbon, namely, Filtrasorb 400 and Nuchar SA, were functionalized by quaternary ammonium salts (quats), as to enhance perchlorate adsorption. Results showed that the adsorption of quats on Nuchar SA increased with increase in chain length (hydrophobicity) of quats. Filtrasorb 400, however, had limited uptake of long-chain quats such as dodecyl- trimethylammonium and hexadecyltrimethylammoium (HDTMA). Results indicated that perchlorate removal by the functionalized activated carbon was directly related to the chain length of the modifying quats. Perchlorate removal by functionalized activated carbon increased with increase in chain length of the modifying quats and became less pH-dependent. Modified Nuchar SA had higher overall perchlorate removal capacity than the modified Filtrasorb F400, but was more strongly affected by pH than Filtrasorb 400. Activated carbon treated with HDTMA exhibited the best perchlorate removal capacity among all quats studied. Results indicated that tailoring the activated carbon surface with HDTMA rendered the activated carbon surface positively charged, which resulted in substantial increase in perchlorate removal compared to unfunctionalized activated carbons. 展开更多
关键词 PERCHLORATE activated carbon REMOVAL func-tionalization quatemary ammonium salts
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Density Functional Study on the Reaction Mechanism for the Reaction of Ni^+ with Ethane 被引量:2
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作者 张冬菊 刘成卜 +1 位作者 刘永军 胡海泉 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2002年第3期220-226,共7页
The mechanism of the reaction of Ni^+ (~2D) with ethane in the gas-phase wasstudied by using density functional theory. Both the B3LYP and BLYP functionals with standardall-electron basis sets are used to give the det... The mechanism of the reaction of Ni^+ (~2D) with ethane in the gas-phase wasstudied by using density functional theory. Both the B3LYP and BLYP functionals with standardall-electron basis sets are used to give the detailed information of the potential energy surface(PES) of [Ni, C_2, H_6]^+. The mechanisms forming the products CH_4 and H_2 in the reaction of Ni^+with ethane are proposed. The reductive eliminations of CH_4 and H_2 are typicaladdition-elimination reactions. Each of the two reactions consists of two elementary steps; C―C orC―H bond activations to form inserted species followed by isomerizations to form product-likeintermediate. The rate determining steps for the elimination reactions of forming CH_4 and H_2 arethe isomerizations of the inserted species rather than C―C or C―H bond activations. Theelimination reaction of forming H_2 was found to be thermodynamically favored compared to that ofCH_4. 展开更多
关键词 Ni^+ C_2H_6 reaction mechanism density func- tional theory
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Infinite Horizon Backward Doubly Stochastic Differential Equations with Non-degenerate Terminal Functions and Their Stationary Property
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作者 Hui-nan LENG 《Acta Mathematicae Applicatae Sinica》 SCIE CSCD 2016年第2期407-422,共16页
In this paper we consider infinite horizon backward doubly stochastic differential equations (BDS- DEs for short) coupled with forward stochastic differential equations, whose terminal functions are non-degenerate. ... In this paper we consider infinite horizon backward doubly stochastic differential equations (BDS- DEs for short) coupled with forward stochastic differential equations, whose terminal functions are non-degenerate. For such kind of BDSDEs, we study the existence and uniqueness of their solutions taking values in weighted Lp(dx)¤L2(dx)space (p _〉 2), and obtain the stationary property for the solutions. 展开更多
关键词 backward doubly stochastic differential equations infinite horizon non-degenerate terminal func-tion stationary property
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PERIODIC SOLUTION TO PREDATOR-PREY CHAIN SYSTEM WITH IMPULSIVE EFFECTS AND BEDDINGTON-DEANGELIS FUNCTIONAL RESPONSE
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作者 Yao Zhijian (Dept. of Math. and Physics, Anhui Institute of Architecture and Industry, Hefei 230601) 《Annals of Differential Equations》 2008年第3期367-378,共12页
In this paper, a predator-prey chain system with impulsive effects and Beddington-DeAngelis functional response is studied. We investigate the existence of periodic solu-tion by coincidence degree theory. Sufficient c... In this paper, a predator-prey chain system with impulsive effects and Beddington-DeAngelis functional response is studied. We investigate the existence of periodic solu-tion by coincidence degree theory. Sufficient conditions are obtained for the existence of periodic solution. 展开更多
关键词 IMPULSIVE predator-prey chain system Beddington-DeAngelis func-tional response periodic solution coincidence degree
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EVANS FUNCTIONS AND INSTABILITY OF A STANDING PULSE SOLUTION OF A NONLINEAR SYSTEM OF REACTION DIFFUSION EQUATIONS
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作者 Linghai Zhang 《Annals of Applied Mathematics》 2016年第1期79-101,共23页
In this paper, we consider a nonlinear system of reaction diffusion equa- tions arising from mathematical neuroscience and two nonlinear scalar reaction diffusion equations under some assumptions on their coefficients... In this paper, we consider a nonlinear system of reaction diffusion equa- tions arising from mathematical neuroscience and two nonlinear scalar reaction diffusion equations under some assumptions on their coefficients. The main purpose is to couple together linearized stability criterion (the equivalence of the nonlinear stability, the linear stability and the spectral sta- bility of the standing pulse solutions) and Evans functions to accomplish the existence and instability of standing pulse solutions of the nonlinear system of reaction diffusion equations and the nonlinear scalar reaction diffusion equa- tions. The Evans functions for the standing pulse solutions are constructed explicitly. 展开更多
关键词 nonlinear system of reaction diffusion equations standing pulse solutions existence INSTABILITY linearized stability criterion Evans func- tions
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胰岛素强化疗法序贯司美格鲁肽治疗肥胖中青年T2DM患者的临床疗效与安全性研究 被引量:1
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作者 陈雪辉 尹清风 +4 位作者 孟祥雨 耿锐娜 王旭 徐云 白立炜 《海南医学》 2025年第8期1098-1103,共6页
目的探讨胰岛素强化疗法序贯司美格鲁肽治疗肥胖中青年T2DM患者的临床疗效及安全性。方法前瞻性选取2021年8月至2024年2月新乡医学院第一附属医院收治的120例肥胖中青年T2DM患者纳入研究,按随机数表法分为观察组和对照组各60例。两组患... 目的探讨胰岛素强化疗法序贯司美格鲁肽治疗肥胖中青年T2DM患者的临床疗效及安全性。方法前瞻性选取2021年8月至2024年2月新乡医学院第一附属医院收治的120例肥胖中青年T2DM患者纳入研究,按随机数表法分为观察组和对照组各60例。两组患者均予以胰岛素泵强化降糖,待高血糖状态解除后,对照组序贯二甲双胍治疗,观察组于对照组基础上序贯司美格鲁肽治疗,治疗3个月。比较两组患者治疗前后的空腹血糖(FBG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)、葡萄糖目标范围内时间(TIR)、体质量指数(BMI)、内脏脂肪指数(VAI)、胰岛β细胞功能[胰岛素抵抗指数(HOMA-IR)、空腹C肽、餐后1 h C肽、胰岛素敏感性检测指数(QUICKI)]、血脂[总胆固醇、甘油三酯、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]、血清内酯素(Visfatin)、网膜素-1(omentin-1)、趋化素(Chemerin),同时比较两组患者治疗期间的不良反应发生情况。结果治疗后,观察组患者的FBG、2 hPG、HbA1c、BMI、VAI分别为(5.34±0.71)mmoL/L、(9.00±0.84)mmoL/L、(5.76±0.51)%、(24.26±0.35)kg/m^(2)、3.15±0.71,明显低于对照组的(6.02±0.56)mmoL/L、(11.35±1.01)mmoL/L、(6.28±0.40)%、(26.00±0.49)kg/m^(2)、3.54±0.64,TIR为(95.00±1.52)%,明显高于对照组的(88.46±3.71)%,差异均有统计学意义(P<0.05);治疗后,观察组患者的HOMA-IR为2.16±0.32,明显低于对照组的2.65±0.40,空腹C肽、餐后1 h C肽、QUICKI分别为(3.85±0.27)ng/mL、(7.64±0.43)ng/mL、0.52±0.13,明显高于对照组的(3.02±0.46)ng/mL、(6.02±0.38)ng/mL、0.41±0.10,差异均有统计学意义(P<0.05);治疗后,观察组患者的总胆固醇、甘油三酯、LDL-C、Vaspin、chemerin分别为(3.25±0.42)mmoL/L、(1.77±0.25)mmoL/L、(1.89±0.42)mmoL/L、(70.92±4.68)ng/L、(45.84±4.90)ng/L,明显低于对照组的(3.90±0.53)mmoL/L、(2.08±0.34)mmoL/L、(2.21±0.36)mmoL/L、(75.00±5.15)ng/L、(51.03±5.66)ng/L,HDL-C、omentin-1分别为(1.27±0.11)mmoL/L、(218.45±16.63)pg/mL,明显高于对照组的(1.19±0.13)mmoL/L、(149.60±15.35)pg/mL,差异均有统计学意义(P<0.05);治疗期间两组患者的不良反应总发生率比较差异无统计学意义(P>0.05)。结论胰岛素强化疗法序贯司美格鲁肽治疗肥胖中青年T2DM可降低患者血糖,恢复胰岛β细胞功能,调节血脂,减轻体质量,且安全性较高。 展开更多
关键词 肥胖 中青年 2型糖尿病 司美格鲁肽 血糖 胰岛Β细胞功能 不良反应
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2025版GOLD解读 被引量:2
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作者 何权瀛 《中国医药导刊》 2025年第1期58-63,共6页
2025版慢性阻塞性肺疾病全球创议(GOLD)已发布,包括五章,第一章定义和概述,第二章诊断和评估,第三章慢阻肺的预防和管理,第四章慢阻肺急性加重的管理,第五章慢阻肺合并症。较以往版本,2025版GOLD在许多方面做出重大更新,删除了2024版GOL... 2025版慢性阻塞性肺疾病全球创议(GOLD)已发布,包括五章,第一章定义和概述,第二章诊断和评估,第三章慢阻肺的预防和管理,第四章慢阻肺急性加重的管理,第五章慢阻肺合并症。较以往版本,2025版GOLD在许多方面做出重大更新,删除了2024版GOLD中“第六章COVID-19与慢阻肺”,新增并扩充修订了人体肺功能变化轨迹、微生态失衡、肺功能检查、慢阻肺CT影像学检查、慢阻肺患者心血管病风险、气候变化对慢阻肺患者的相应影响、对慢阻肺患者的推荐疫苗、肺康复治疗的线上、线下及远程随访、随访期治疗药物、LABA+ICS患者停用ICS、肺动脉高压等有关内容。基于此,本研究针对2025版GOLD主要更新内容进行分析解读,并基于慢阻肺发病率问题、肺气肿问题、慢阻肺和肺结核关系问题、慢阻肺患者多种共存疾病的综合评估问题、稳定期慢阻肺的病情评估问题、不应推荐肺去神经靶向治疗问题、慢阻肺患者共存病问题、慢阻肺合并贫血问题、慢阻肺患者合并红细胞增多症问题、慢阻肺合并心力衰竭问题、PRISm的临床意义阐释问题、肺的过度充气问题、慢阻肺患者吸入ICS后是否会发生肺癌问题等进行讨论,以期为临床实践提供理论参考。 展开更多
关键词 慢性阻塞性肺疾病全球创议(GOLD) 慢性阻塞性肺疾病(慢阻肺) 肺功能 解读
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百令胶囊联合紫杉醇+顺铂化疗在非小细胞肺癌合并肺结核患者中的应用效果
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作者 孙冰 杨亚勤 +1 位作者 黄健 崔秀琴 《癌症进展》 2025年第8期936-939,共4页
目的探讨百令胶囊联合紫杉醇^(+)顺铂化疗在非小细胞肺癌(NSCLC)合并肺结核患者中的应用效果。方法依据治疗方式的不同将150例NSCLC合并肺结核患者分为对照组(n=72)和观察组(n=78),两组患者均接受标准方案肺结核治疗,在此基础上,对照组... 目的探讨百令胶囊联合紫杉醇^(+)顺铂化疗在非小细胞肺癌(NSCLC)合并肺结核患者中的应用效果。方法依据治疗方式的不同将150例NSCLC合并肺结核患者分为对照组(n=72)和观察组(n=78),两组患者均接受标准方案肺结核治疗,在此基础上,对照组患者接受紫杉醇^(+)顺铂治疗,观察组患者接受百令胶囊联合紫杉醇^(+)顺铂治疗。比较两组患者的临床疗效、免疫功能指标(CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+))、凝血功能指标[D-二聚体(D-D)、纤维蛋白原(FIB)]、不良反应发生情况及生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]。结果观察组患者的治疗总有效率为58.97%,高于对照组患者的40.28%,差异有统计学意义(P﹤0.05)。治疗后,两组患者CD4^(+)水平及CD4^(+)/CD8^(+)均高于本组治疗前,CD8^(+)水平均低于本组治疗前,观察组患者CD4^(+)水平及CD4^(+)/CD8^(+)均高于对照组,CD8^(+)水平低于对照组,差异均有统计学意义(P﹤0.05)。治疗后,两组患者D-D、FIB水平均低于本组治疗前,观察组患者D-D、FIB水平均低于对照组,差异均有统计学意义(P﹤0.05)。治疗后,两组患者EORTC QLQ-C30各维度评分均高于本组治疗前,观察组患者EORTC QLQ-C30各维度评分均高于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的不良反应总发生率为39.74%,低于对照组患者的56.94%,差异有统计学意义(P﹤0.05)。结论百令胶囊联合紫杉醇^(+)顺铂化疗可有效提高NSCLC合并肺结核患者的免疫功能,改善凝血功能指标,降低不良反应发生率,提高患者的生活质量。 展开更多
关键词 百令胶囊 非小细胞肺癌 肺结核 免疫功能 凝血功能 不良反应 生活质量
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腹腔镜顺行双保前列腺癌根治术治疗前列腺癌的临床应用价值
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作者 韩广业 马阔 +3 位作者 宋伟航 刘沛 张少华 范毛川 《海南医学》 2025年第13期1879-1884,共6页
目的探讨腹腔镜顺行双保前列腺癌根治术(LabNSRP)对前列腺癌患者应激激素、尿动力学及术后并发症的影响。方法选取2021年3月至2024年2月新乡医学院第一附属医院收治的80例前列腺癌患者纳入研究,采用随机数表法分为对照组和观察组各40例... 目的探讨腹腔镜顺行双保前列腺癌根治术(LabNSRP)对前列腺癌患者应激激素、尿动力学及术后并发症的影响。方法选取2021年3月至2024年2月新乡医学院第一附属医院收治的80例前列腺癌患者纳入研究,采用随机数表法分为对照组和观察组各40例,对照组患者行腹腔镜前列腺癌根治术(LRP),观察组患者行LabNSRP。比较两组患者的围术期指标,术前及术后24 h、72 h的血清应激激素[促生长激素(GH)、促肾上腺皮质激素(ACTH)、皮质醇(Cor)]水平,术前及术后3个月的性激素水平[二氢睾固酮(DHT)、促黄体生成素(LH)、游离睾酮(FT)、促卵泡激素(FSH)],尿动力学指标(尿道闭合压、膀胱容量、尿流率、残余尿量),勃起功能评分(IIEF-5)及前列腺癌治疗与功能评价生活质量量表(FACT-P)评分,统计两组患者术后并发症发生率。结果观察组患者的手术时间、术后拔管及住院时间分别为(135.78±18.77)min、(6.52±1.49)d、(9.27±1.09)d,明显短于对照组的(146.12±25.69)min、(7.34±2.05)d、(10.74±2.18)d,差异均有统计学意义(P<0.05),但两组患者的术中出血量、术后引流量及肠功能恢复时间比较差异均无统计学意义(P>0.05)。观察组患者术后24 h、72 h的血清GH、ACTH、Cor水平明显低于对照组,差异均有统计学意义(P<0.05)。术后3个月,观察组患者的LH、FSH、DHT及FT水平分别为(7.14±0.75)U/L、(10.27±1.25)U/L、(592.84±48.96)ng/L、(0.37±0.07)nmol/L,明显高于对照组的(6.58±0.67)U/L、(8.94±1.17)U/L、(557.49±45.26)ng/L、(0.32±0.06)nmol/L,差异均有统计学意义(P<0.05)。术后3个月,观察组患者的尿流率、尿道闭合压、膀胱容量分别为(18.24±1.37)mL/s、(72.39±4.28)cm H_(2)O、(349.84±18.25)mL,明显高(多)于对照组的(15.42±1.22)mL/s、(69.25±4.13)cm H_(2)O、(332.14±15.13)mL,残余尿量为(25.24±3.02)mL,明显少于对照组的(31.29±3.98)mL,差异均有统计学意义(P<0.05);术后3个月,观察组患者的IIEF-5及FACT-P评分分别为(21.27±1.63)分、(118.47±10.25)分,明显高于对照组的(18.94±1.57)分、(102.37±14.87)分,差异均有统计学意义(P<0.05)。观察组患者术后并发症总发生率为5.00%,明显低于对照组的22.50%,差异有统计学意义(P<0.05)。结论LabNSRP治疗前列腺癌创伤小、手术效率高,可保护患者性功能和尿控功能,提高生活质量。 展开更多
关键词 前列腺癌 腹腔镜顺行双保前列腺癌根治术 性功能 生活质量 并发症
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智能化康复机器人配合四肢联动疗法运动训练对急性缺血性脑卒中后肢体功能障碍患者运动功能和预后的影响
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作者 杜迎春 高延伦 +1 位作者 侯兵兵 姚鸣鸣 《海南医学》 2025年第13期1866-1871,共6页
目的探讨智能化康复机器人辅助四肢联动疗法(Nustep-t4)在急性缺血性脑卒中(AIS)后肢体功能障碍患者中的应用价值。方法选取2023年3月至2024年5月平顶山市第一人民医院收治的124例AIS后肢体功能障碍患者作为研究对象,按照随机数表法将... 目的探讨智能化康复机器人辅助四肢联动疗法(Nustep-t4)在急性缺血性脑卒中(AIS)后肢体功能障碍患者中的应用价值。方法选取2023年3月至2024年5月平顶山市第一人民医院收治的124例AIS后肢体功能障碍患者作为研究对象,按照随机数表法将患者分为对照组和观察组各62例。两组患者均进行常规康复训练,对照组采用Nustep-t4运动训练,观察组在对照组基础上联合智能化康复机器人治疗,均治疗两周。比较两组患者的治疗效果以及治疗前、治疗两周后、出院90 d后肢体运动功能[Fugl-Meyer运动功能量表下肢部分(FMA-L)、躯干控制能力测试(TCT)、Berg平衡量表(BBS)、功能性步行量表(FAC)、6 min步行距离]、神经功能[美国国立卫生院卒中量表(NIHSS)评分]、预后情况[Rankin修订量表评分(mRS)]、日常生活能力[改良Barthel指数评定量表(MBI)]和生活质量[脑卒中生存质量量表(SS-QOL)]。结果观察组患者的治疗总有效率为93.55%,明显高于对照组的80.65%,差异有统计学意义(P<0.05);观察组患者治疗2周后的FMA-L评分、TCT评分、BBS评分、FAC评分、6 min步行距离分别为(22.71±2.81)分、(48.59±4.53)分、(20.18±3.17)分、(2.03±0.28)分、(22.65±2.10)m,明显高(长)于对照组的(20.36±2.60)分、(44.01±3.96)分、(17.95±3.42)分、(1.74±0.24)分、(18.77±1.86)m,出院90 d后的FMA-L评分、TCT评分、BBS评分、FAC评分、6 min步行距离分别为(28.72±2.11)分、(73.61±7.03)分、(44.51±4.72)分、(3.41±0.59)分、(41.13±3.30)m,明显高(长)于对照组的(24.67±3.52)分、(61.95±5.82)分、(39.24±5.10)分、(2.67±0.46)分、(34.62±2.77)m,差异均有统计学意义(P<0.05);观察组患者治疗两周后的NIHSS评分、mRs评分分别为(9.18±1.72)分、(3.05±0.22)分,明显低于对照组的(10.24±2.80)分、(3.57±0.27)分,出院90 d后的NIHSS评分、mRs评分分别为(7.20±1.06)分、(2.53±0.18)分,明显低于对照组的(8.33±1.14)分、(3.01±0.24)分,差异均有统计学意义(P<0.05);观察组患者治疗两周后的MBI评分、SS-QOL评分分别为(55.17±6.06)分、(141.27±12.39)分,明显高于对照组的(50.24±5.28)分、(130.73±11.45)分,出院90 d后MBI评分、SS-QOL评分分别为(72.34±8.03)分、(185.12±21.39)分,明显高于对照组的(64.82±6.94)分、(163.73±17.45)分,差异均有统计学意义(P<0.05)。结论智能化康复机器人辅助Nustep-t4运动训练治疗AIS后肢体功能障碍能减轻患者神经功能缺损程度,恢复肢体功能,改善预后,提高生活质量,临床应用效果显著。 展开更多
关键词 缺血性脑卒中 功能障碍 运动训练 Nustep-t4 机器人 肢体功能 平衡功能 生活质量
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