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Frequently cutting restriction enzymes: Clearing the fog to see the ends
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作者 María I. Vaquero-Sedas Miguel A. Vega-Palas 《American Journal of Molecular Biology》 2013年第1期59-61,共3页
Telomeres, which are found at the ends of eukaryotic chromosomes, are composed of tandem arrays of repetitive sequences and safeguard genomic stability. Previous studies have revealed that telomeric repeats are also p... Telomeres, which are found at the ends of eukaryotic chromosomes, are composed of tandem arrays of repetitive sequences and safeguard genomic stability. Previous studies have revealed that telomeric repeats are also present at internal chromosomal loci in many eukaryotes. However, the biological role of these interstitial telomeric sequences (ITSs) remains unknown. The integrity of telomeric length and chromatin structure is required for telomere stability. However, the study of these telomeric features can be impeded by the presence of ITSs. Frequently cutting restriction enzymes have been revealed to be very useful tools for the study of the length and chromatin structure of telomeres independent of the presence of ITSs. 展开更多
关键词 Telomeric Length Telomeric CHROMATIN Structure frequently CUTTING RESTRICTION Enzymes Arabidopsis THALIANA
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Frequently Asked Questions About Ancient Olympics
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《英语自学》 2000年第8期2-4,共3页
1.Where did the Olympic gamescome from?There are many different stories about the be-ginning of the Olympics.One myth says that the guardians of the infantgod Zeus held the first footrace,or that Zeus himselfstarted t... 1.Where did the Olympic gamescome from?There are many different stories about the be-ginning of the Olympics.One myth says that the guardians of the infantgod Zeus held the first footrace,or that Zeus himselfstarted the Games to celebrate his victory over his fa-ther Cronus for control of the world.Another tradi-tion states that after the Greek hero Pelops won achariot race against King Oenomaus to marry Oeno- 展开更多
关键词 GREEK frequently Asked Questions About Ancient Olympics
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Oral mucositis induced by risperidone:rare side effect of a frequently prescribed medication
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作者 Andrea Aguglia Andrea Amerio +3 位作者 Luca Proietti Alessandra Costanza Gianluca Serafini Mario Amore 《General Psychiatry》 CSCD 2020年第5期366-368,共3页
Risperidone is a safe second-generation antipsychotic which is rarely associated with the emergence of a few adverse effects,such as oral lesions and stomatitis.We report the case of a 77-year-old woman affected by a ... Risperidone is a safe second-generation antipsychotic which is rarely associated with the emergence of a few adverse effects,such as oral lesions and stomatitis.We report the case of a 77-year-old woman affected by a neurocognitive disorder with psychotic features and treated with risperidone 2 mg/day.After 1 week,she showed a burning mouth syndrome with oral lesions and risperidone was discontinued.Antipsychotic-induced oral ulcerations may be caused by the reduction of saliva protection with minor adverse effects related to oral movement disorders or impairment of the bacterial flora of saliva. 展开更多
关键词 frequent MEDICATION IMPAIRMENT
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Usefulness of mizoribine administration in children with frequently relapsing nephrotic syndrome, and the relationship between pharmacokinetic parameters and efficacy: a multicenter prospective cohort study in China 被引量:5
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作者 Zheng-Kun Xia Yuan-Fu Gao +5 位作者 Li-Ping Rong Xi-Qiang Dang Qian Shen Xiao-Yun Jiang Zhu-Wen Yi Hong Xu 《World Journal of Pediatrics》 SCIE CAS CSCD 2019年第3期262-269,共8页
Background Mizoribine (MZR) is an immunosuppressant used to treat adult nephropathy.There is little experience with the drug in treating Chinese children with frequently relapsing nephrotic syndrome (FRNS).We investig... Background Mizoribine (MZR) is an immunosuppressant used to treat adult nephropathy.There is little experience with the drug in treating Chinese children with frequently relapsing nephrotic syndrome (FRNS).We investigated the efficacy and safety for treating MZR with FRNS.Furthermore,the relationship between efficacy and serum concentration was investigated.Methods A prospective multicenter observational 12-month study was performed for evaluating the usefulness of MZR with FRNS.Serum MZR concentration was measured,and the relationships between pharmacokinetic parameters (Cmax,AUC),number of relapses,and urinary protein were evaluated.Results Eighty-two pediatric patients from four hospitals were treated with MZR and prednisone.MZR treatment significantly reduced the number of relapses and steroid doses.A correlation between pharmacokinetic parameters and relapses was observed,which fits well with the sigmoidal Emax model.Even in the relationship between pharmacokinetic parameters and urinary proteins,it was recognized that there was a threshold in the pharmacokinetic parameters for the therapeutic effect similar to the results obtained with the sigmoidal Emax model.Eleven patients (13.4%) experienced mild adverse events.Conclusions MZR therapy was effective in reducing the number of relapses and steroid doses.No severe adverse reactions were observed.Therapeutically effective serum concentrations were estimated to be Cmax > about 2 μg/mL or AUC > about 10 lag h/mL.MZR and steroid treatment were effective and safe for pediatric FRNS. 展开更多
关键词 frequently relapsing nephrotic syndrome MIZORIBINE PHARMACOKINETIC parameters
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EXCHANGE CENTER STAGE The past decade brought increasingly frequent China-Vietnam theatrical exchanges through multiple channels
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作者 Peng Shituan 《China Report ASEAN》 2025年第1期24-26,共3页
China and Vietnam have maintained close theatrical exchange.A group of Vietnamese students studied at the Central Academy of Drama and the National Academy of Chinese Theatre Arts(NACTA)of China in the 1950s and’60s.... China and Vietnam have maintained close theatrical exchange.A group of Vietnamese students studied at the Central Academy of Drama and the National Academy of Chinese Theatre Arts(NACTA)of China in the 1950s and’60s.The past decade has witnessed steadily improving relations between the two countries.Their cultural exchange,especially in theatrical arts,has become increasingly fruitful in three distinct ways. 展开更多
关键词 maintained VIETNAM frequent
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汤姆·凯里奇的健康新生活
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作者 万思思 《疯狂英语(新读写)》 2025年第6期15-20,74,75,共8页
通过坚持每周健身六天,汤姆·凯里奇成功改善了身心健康状况。Celebrated chef and Great British Menu judge Tom Kerridge hits the gym six days a week to maintain his mental and physical health.The culinary star,who is a... 通过坚持每周健身六天,汤姆·凯里奇成功改善了身心健康状况。Celebrated chef and Great British Menu judge Tom Kerridge hits the gym six days a week to maintain his mental and physical health.The culinary star,who is a two‑Michelin‑starred pub owner,explained his switch from swimming to gym workouts was due to the frequent travel his job needs,noting the challenge of finding hotels with pools. 展开更多
关键词 Tom Kerridge Gym workouts Physical health Frequent travel Mental health
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TGI-FPR: An Improved Multi-Label Password Guessing Model
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作者 Wei Ou Shuai Liu +3 位作者 Mengxue Pang Jianqiang Ma Qiuling Yue Wenbao Han 《Computers, Materials & Continua》 2025年第7期463-490,共28页
TarGuess-I is a leading model utilizing Personally Identifiable Information for online targeted password guessing.Due to its remarkable guessing performance,the model has drawn considerable attention in password secur... TarGuess-I is a leading model utilizing Personally Identifiable Information for online targeted password guessing.Due to its remarkable guessing performance,the model has drawn considerable attention in password security research.However,through an analysis of the vulnerable behavior of users when constructing passwords by combining popular passwords with their Personally Identifiable Information,we identified that the model fails to consider popular passwords and frequent substrings,and it uses overly broad personal information categories,with extensive duplicate statistics.To address these issues,we propose an improved password guessing model,TGI-FPR,which incorporates three semantic methods:(1)identification of popular passwords by generating top 300 lists from similar websites,(2)use of frequent substrings as new grammatical labels to capture finer-grained password structures,and(3)further subdivision of the six major categories of personal information.To evaluate the performance of the proposed model,we conducted experiments on six large-scale real-world password leak datasets and compared its accuracy within the first 100 guesses to that of TarGuess-I.The results indicate a 2.65%improvement in guessing accuracy. 展开更多
关键词 Password analysis personally identifiable information frequent substring password guessing model
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Favorable Policies For Titanium Tube Industry Are Unveiled Frequently in 2016
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《China Nonferrous Metals Monthly》 2016年第9期6-7,共2页
For the titanium tube industry in 2016,the widespread loss in the industry in 2015 will quicken the adjustment pace of product structure in the tube market,and create new industrial situation;furthermore,the'One B... For the titanium tube industry in 2016,the widespread loss in the industry in 2015 will quicken the adjustment pace of product structure in the tube market,and create new industrial situation;furthermore,the'One Belt,One Road'plan in the'Thirteenth Five Year'Plan will also boost demand in the tube market.Meanwhile,due to the tremendous base in capacity and output,and excessively long absorption time;coupled with heavy 展开更多
关键词 WILL Favorable Policies For Titanium Tube Industry Are Unveiled frequently in 2016
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Impact of sarcopenia on the progression of nonalcoholic fatty liver disease: a frequently forgotten association
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作者 Andrew A.Li Aijaz Ahmed Donghee Kim 《Hepatobiliary Surgery and Nutrition》 SCIE 2019年第3期260-261,共2页
The development of sarcopenia in patients with chronic liver disease has been recognized as a predictor of poor outcome.Sarcopenia,or the progressive loss of skeletal muscle mass begins to manifest in the early stages... The development of sarcopenia in patients with chronic liver disease has been recognized as a predictor of poor outcome.Sarcopenia,or the progressive loss of skeletal muscle mass begins to manifest in the early stages of chronic liver disease and worsens with progression to advanced liver disease with a prevalence approaching 60%in patients with end-stage liver disease(1). 展开更多
关键词 frequent SKELETAL APPROACHING
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基于改进FP-growth算法的食品风险因素关联分析方法
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作者 于家斌 马欣玥 +5 位作者 赵峙尧 王小艺 张新 崔晓玉 白玉廷 陈帅祥 《食品科学》 EI CAS CSCD 北大核心 2024年第23期250-258,共9页
为解决传统食品安全监督抽检“随机抽”模式存在的抽检决策主观性强、靶向性不高的问题,本研究提出一种基于改进Frequent Pattern-growth(FP-growth)算法的食品风险因素关联分析方法。首先,采用熵权法分别对食品种类的风险指标进行权重... 为解决传统食品安全监督抽检“随机抽”模式存在的抽检决策主观性强、靶向性不高的问题,本研究提出一种基于改进Frequent Pattern-growth(FP-growth)算法的食品风险因素关联分析方法。首先,采用熵权法分别对食品种类的风险指标进行权重分配,以计算出不同食品种类的风险指数。其次,以风险指数为特征,基于小批量K均值算法(MiniBatchKmeans)进行风险聚类,得到食品的风险等级。最后,采用带约束的改进FP-growth算法进行食品风险因素关联规则挖掘,挖掘食品风险等级与食品种类、时间、地域属性信息之间的关联关系,并对挖掘出的结果进行关联分析,从而为精准靶向引导抽检决策提供指导。本研究依托2019年中国某些地区的食品抽检数据进行分析,对其进行指标赋权,计算风险指数;后经过风险聚类为低风险、中风险和高风险;最后,将数据导入改进FPgrowth算法,得到食品风险因素关联规则。通过对比实验得到结果:对于17214条抽检数据,本研究提出的改进FP-growth算法相较于Apriori算法运行时间短;相较于传统FP-growth算法,删除了无效规则,提高了对食品风险因素关联规则的分析效率,从而为食品监管部门抽检工作提供了准确、高效的决策依据。 展开更多
关键词 食品安全监督抽检 关联分析 熵权法 MinibatchKmeans聚类 Frequent Pattern-growth算法
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A giant scrotal pendulous fibroma mimicking a supernumerary testis
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作者 Luigi Quaresima Rocco Francesco Delle Fave +2 位作者 Giordano Polisini Daniela Fasanella Willy Giannubilo 《Asian Journal of Andrology》 SCIE CAS CSCD 2024年第2期227-228,共2页
DearEditor,Pendulous fibroma,also called acrochordon,is a benign skin neoplasm,originating from the dermis.Usually,small in size,it can arise from any point of the dermis(frequently from the axillary area,inguinal reg... DearEditor,Pendulous fibroma,also called acrochordon,is a benign skin neoplasm,originating from the dermis.Usually,small in size,it can arise from any point of the dermis(frequently from the axillary area,inguinal region,eyelid,or neck),and in some cases,it can be unesthetic.Pendulous fibromas are more frequent in obese subjects,and most of the time,they are sporadic,although sometimes,they can be observed in Birt-Hogg-Dube syndrome.In some rare cases,they can reach considerable dimensions.Occasionally,they are associated with diabetes mellitus,obesity,and intestinal polyps.Often,the pedicle undergoes torsion,causing pain and ischemic necrosis of the fibroma,which requires rapid removal of the tumor.We present a case of giant pendulous fibroma of the scrotum.The patient has given his consent to the publication of his clinical information and photographic images in an anonymous form. 展开更多
关键词 frequent OBESITY clinical
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Thoracoscopic resection of giant left atrial appendage aneurysm: A case report
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作者 Jie Han Jiakan Weng Jiwen Li 《Laparoscopic, Endoscopic and Robotic Surgery》 2024年第1期48-51,共4页
Left atrial appendage aneurysm(LAAA)was first reported in the 1960s.1 LAAA is a rare condition,with just over 100 congenital or acquired cases reported to date.2 LAAA is frequently diagnosed incidentally during echoca... Left atrial appendage aneurysm(LAAA)was first reported in the 1960s.1 LAAA is a rare condition,with just over 100 congenital or acquired cases reported to date.2 LAAA is frequently diagnosed incidentally during echocardiography or computed tomography(CT)scans.Most patients with LAAA are asymptomatic,while a few exhibit nonspecific symptoms,such as dyspnea,palpitation,and chest tightness.Patients with LAAA frequently present with atrial arrhythmias and systemic thromboembolism,such as stroke or multiorgan infarctions,due to the formation of a left atrial appendage thrombus.3 The lesion may be cured using aneurysm resection.Considering it as the potential cause of atrial arrhythmias and thromboembolism,the lesion must be identified on time and cured using a suitable treatment approach. 展开更多
关键词 ATRIAL ANEURYSM frequent
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基于HowNet语义相似度的FAQ研究 被引量:10
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作者 贾可亮 樊孝忠 张禹 《计算机应用》 CSCD 北大核心 2007年第9期2256-2257,共2页
FAQ是网站提供在线帮助的主要手段。利用检索机制根据用户提出的问题建立一个候选问句集,利用知网研究了用户问句和候选问句之间的相似度,从中找出最相似的问句,并将相应答案返回给用户。实验表明,该方法提高了问句匹配的准确率。
关键词 知网 frequently Asked Question(FAQ) 句子语义相似度
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A related degree-based frequent pattern mining algorithm for railway fault data
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作者 Jiaxu Guo Ding Ding +2 位作者 Peihan Yang Qi Zou Yaping Huang 《High-Speed Railway》 2024年第2期101-109,共9页
It is of great significance to improve the efficiency of railway production and operation by realizing the fault knowledge association through the efficient data mining algorithm.However,high utility quantitative freq... It is of great significance to improve the efficiency of railway production and operation by realizing the fault knowledge association through the efficient data mining algorithm.However,high utility quantitative frequent pattern mining algorithms in the field of data mining still suffer from the problems of low time-memory performance and are not easy to scale up.In the context of such needs,we propose a related degree-based frequent pattern mining algorithm,named Related High Utility Quantitative Item set Mining(RHUQI-Miner),to enable the effective mining of railway fault data.The algorithm constructs the item-related degree structure of fault data and gives a pruning optimization strategy to find frequent patterns with higher related degrees,reducing redundancy and invalid frequent patterns.Subsequently,it uses the fixed pattern length strategy to modify the utility information of the item in the mining process so that the algorithm can control the length of the output frequent pattern according to the actual data situation and further improve the performance and practicability of the algorithm.The experimental results on the real fault dataset show that RHUQI-Miner can effectively reduce the time and memory consumption in the mining process,thus providing data support for differentiated and precise maintenance strategies. 展开更多
关键词 High utility QUANTITATIVE Frequent pattern mining Related degree pruning Fixed pattern length
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LFU算法的ASIC实现
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作者 黄秀荪 仇玉林 叶青 《电子器件》 CAS 2007年第1期237-240,共4页
为ASIC实现内存管理中页面替换的LFU算法,基于TSMC公司0.18μm的单元库,用标准逻辑单元库实现LFU算法.通过研究一组数中的最小值检出和最小值地址检出的逻辑规律,简化逻辑,减小了电路规模.通过控制关键路径的级数,达到了减少延迟,提高... 为ASIC实现内存管理中页面替换的LFU算法,基于TSMC公司0.18μm的单元库,用标准逻辑单元库实现LFU算法.通过研究一组数中的最小值检出和最小值地址检出的逻辑规律,简化逻辑,减小了电路规模.通过控制关键路径的级数,达到了减少延迟,提高运行速度的目的.给出了版图和静态时序分析结果. 展开更多
关键词 LFU(Least frequently used) ASIC内存管理
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Fast FP-Growth for association rule mining 被引量:1
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作者 杨明 杨萍 +1 位作者 吉根林 孙志挥 《Journal of Southeast University(English Edition)》 EI CAS 2003年第4期320-323,共4页
In this paper, we propose an efficient algorithm, called FFP-Growth (shortfor fast FP-Growth) , to mine frequent itemsets. Similar to FP-Growth, FFP-Growth searches theFP-tree in the bottom-up order, but need not cons... In this paper, we propose an efficient algorithm, called FFP-Growth (shortfor fast FP-Growth) , to mine frequent itemsets. Similar to FP-Growth, FFP-Growth searches theFP-tree in the bottom-up order, but need not construct conditional pattern bases and sub-FP-trees,thus, saving a substantial amount of time and space, and the FP-tree created by it is much smallerthan that created by TD-FP-Growth, hence improving efficiency. At the same time, FFP-Growth can beeasily extended for reducing the search space as TD-FP-Growth (M) and TD-FP-Growth (C). Experimentalresults show that the algorithm of this paper is effective and efficient. 展开更多
关键词 data mining frequent itemsets association rules frequent pattern tree(FP-tree)
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A patient presenting painful chest wall swelling: Tietze syndrome 被引量:2
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作者 Kohei Sawada Hiromi Ihoriya +5 位作者 Taihei Yamada Tetsuya Yumoto Kohei Tsukahara Takaaki Osako Hiromichi Naito Atsunori Nakao 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2019年第2期122-124,共3页
Dear editor,Patients frequently visit the emergency room with acute chest pain.While some potentially life-threatening disorders may cause the pain,in approximately 80%of cases,the chest pain source is benign,and musc... Dear editor,Patients frequently visit the emergency room with acute chest pain.While some potentially life-threatening disorders may cause the pain,in approximately 80%of cases,the chest pain source is benign,and musculoskeletal chest pain accounts for nearly 20%– 50%of those cases.^[1–6]Thus,pain caused by benign and pathological conditions of the chest wall encountered in the emergency department is sometimes incorrectly attributed to angina pectoris or pleuritic and other serious cardiopulmonary diseases. 展开更多
关键词 Patients frequently EMERGENCY ROOM LIFE-THREATENING
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Condition Identification Based on Vibration Measurements for Free Spanning Submarine Pipelines 被引量:1
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作者 胡家顺 冯新 +1 位作者 李昕 周晶 《China Ocean Engineering》 SCIE EI 2008年第4期561-574,共14页
Free spanning pipelines are suspended between two points on an uneven seaffoor. The variations of structural conditions, such as the changes in soil property, flow velocity, axial force and span length etc., directly ... Free spanning pipelines are suspended between two points on an uneven seaffoor. The variations of structural conditions, such as the changes in soil property, flow velocity, axial force and span length etc., directly affect working performance of the whole submarine pipeline system. But until now few researches have focused on condition identification for free span (CIFS). A method to identify the operational conditions of free spanning submarine pipelines based on vibration measurements is proposed in this paper. Firstly, the ill-posedness of CIFS is analyzed in detail. Secondly, the framework for CIFS based on the nonlinear kernel discriminant analysis (KDA) is established. Thirdly, the internal structural characteristics of natural frequencies, normalized frequencies and frequency change ratios are studied. And then the condition feature vector for CIFS is extracted by use of the vibration measurements. Finally, the validity of the proposed approach is evaluated by a case study. The results demonstrate that the proposed approach can effectively identify each condition of free span when condition variation occurs even if under measurement noise. It is concluded that the proposed method is a promising tool for CIFS in real applications. 展开更多
关键词 submasine pipelines condition identfication free span kernel discriminant analysis( KDA frequently structure
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New algorithm of mining frequent closed itemsets
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作者 张亮 任永功 付玉 《Journal of Southeast University(English Edition)》 EI CAS 2008年第3期335-338,共4页
A new algorithm based on an FC-tree (frequent closed pattern tree) and a max-FCIA (maximal frequent closed itemsets algorithm) is presented, which is used to mine the frequent closed itemsets for solving memory an... A new algorithm based on an FC-tree (frequent closed pattern tree) and a max-FCIA (maximal frequent closed itemsets algorithm) is presented, which is used to mine the frequent closed itemsets for solving memory and time consuming problems. This algorithm maps the transaction database by using a Hash table,gets the support of all frequent itemsets through operating the Hash table and forms a lexicographic subset tree including the frequent itemsets.Efficient pruning methods are used to get the FC-tree including all the minimum frequent closed itemsets through processing the lexicographic subset tree.Finally,frequent closed itemsets are generated from minimum frequent closed itemsets.The experimental results show that the mapping transaction database is introduced in the algorithm to reduce time consumption and to improve the efficiency of the program.Furthermore,the effective pruning strategy restrains the number of candidates,which saves space.The results show that the algorithm is effective. 展开更多
关键词 frequent itemsets frequent closed itemsets minimum frequent closed itemsets maximal frequent closed itemsets frequent closed pattern tree
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Design of foundation structures of sea-crossing bridges on serviceability limit state
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作者 金伟良 胡琦忠 +2 位作者 帅长斌 于群力 鲁征 《Journal of Southeast University(English Edition)》 EI CAS 2008年第1期74-79,共6页
The target reliability indices of the foundation structures of sea-crossing bridges on the serviceability limit state (SLS) are different from those of common bridges due to their different surroundings. Consequentl... The target reliability indices of the foundation structures of sea-crossing bridges on the serviceability limit state (SLS) are different from those of common bridges due to their different surroundings. Consequently, three levels of the target reliability indices, which are 1.5, 2. 0 and 2. 3, respectively, for those structures on the SLS are suggested based on the Joint Committee on Structural Safety (JCSS) model code, and a new method of calibrating factors of live loads, which is based on the contribution ratio of tensile stresses of reinforcing bars produced by various loads to the maximum crack width of concrete, is proposed. Finally, the calibration of the reliability-based factors of the frequent value and the quasi-permanent value of live loads is conducted by the Joint Committee (JC) method through an actual design, and the indices are proved to be reasonable and the new method is proved to be feasible. 展开更多
关键词 sea-crossing bridges target reliability JC (Joint Committee) method frequent value quasi-permanent value foundation structures
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