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Operational efficiencies and costs of an arm roll forwarder: A case study at Nasu in Tochigi Prefecture, Japan 被引量:1
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作者 Kazuhiro Aruga Yuto Otsuka +3 位作者 Chikara Nakahata Reiko Yamaguchi Masashi Saito Mayu Nagasaki 《Journal of Forestry Research》 SCIE CAS CSCD 2013年第3期577-583,共7页
We investigated a developed arm roll forwarder at Nasu in Tochigi Prefecture, Japan. An arm roll forwarder can only load a steel container that has been fully loaded with logs beforehand, and can later unload such a c... We investigated a developed arm roll forwarder at Nasu in Tochigi Prefecture, Japan. An arm roll forwarder can only load a steel container that has been fully loaded with logs beforehand, and can later unload such a container. Such a forwarder can shorten the loading and untoading times and improve operational efficiency. We examined two operation systems with an arm roll forwarder and a forwarder. In the first system the loading was done with a grapple-loader. In the second system the loading was done with a processor. The loading times of an arm roll forwarder were significantly tess than those of a forwarder. Because the optimal cycle times (excluding the waiting times for an arm roll for- warder) were significantly reduced, the costs of using an arm roll for- warder are lower, although the loading capacity was small and the hourly operation cost was high. The maximum operational efficiencies varied depending on forwarding distances. The second operation system with an arm roll forwarder exhibited the best operational efficiency within a 1,580-m forwarding distance, and beyond that distance it exhibited the highest operational efficiency when a forwarder was used. Similarly, the cost of operation of the system with an arm roll forwarder was the lowest within a 1,130-m forwarding distance, and beyond that distance the cost was the lowest when using the forwarder. Therefore, the arm roll for- warder is effective within a certain forwarding distance. 展开更多
关键词 arm roll forwarder steel container operational efficiency cost forwarding distance
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Comparison of the Ergonomic Characteristics of Forwarders with Stationary and Rotating Cabins
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作者 Petr Filo 《Journal of Agricultural Science and Technology(B)》 2014年第6期476-484,共9页
The research of the ergonomic parameters of two tested forwarders was based on the measurement of a variability of physiological functions of the operator during one work shift. The research included a series of six m... The research of the ergonomic parameters of two tested forwarders was based on the measurement of a variability of physiological functions of the operator during one work shift. The research included a series of six measurements, each lasting l h and starting at 5:00, 12:00 and 17:00 O'clock. The measured operator was at all times the same person. We had a hypothesis that the rate of the measured variability would have to do with the following four factors: forwarder cabin type, terrain character, fatigue during the work shift and work at daylight or in dark. Main findings are described below: during his work with a fixed type of the forwarder cab, the operator's brain waves at the frequency of Gamma, high Beta, Beta and Alpha reached statistically significantly higher average values than during his work with a rotating cab. With a higher degree of terrain roughness and in the forwarder with the rotating cab, the operator showed a significantly higher frequency and lower amplitude of respiration. At the beginning of the work shift, the tension of muscles in the operator's neck was at the significantly lowest level. In the afternoon, at the end of the work shift, the level of muscle tension was the highest. The “daylight/dark” work had a significantly highest impact on volume changes in the amplitude (strength) of blood pulse and on the skin conductance level. All research factors explained together 15%-65% of the variability of physiological functions. 展开更多
关键词 forwarder CABIN ergonomic parameters OPERATOR psycho-physiological functions
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Spirit Over the Saddle:One of the twelve animals of the Chinese zodiac, the Horse embodies vitality, freedom and the spirit of ambition
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作者 LI YIN 《ChinAfrica》 2026年第2期56-57,共2页
In the Chinese lunar calendar,2026 ushers in the Year of the Horse,a creature that has carried humanity across continents and through centuries.More than a marker of time,the horse embodies vitality,courage,and the re... In the Chinese lunar calendar,2026 ushers in the Year of the Horse,a creature that has carried humanity across continents and through centuries.More than a marker of time,the horse embodies vitality,courage,and the relentless spirit to move forward,qualities that resonate not only in China but across the landscapes of many African societies. 展开更多
关键词 HORSE VITALITY chinese zodiac year horse chinese lunar calendar AMBITION COURAGE forward movement
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Modeling Hepatitis B and Alcohol Effects on Liver Cirrhosis Progression
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作者 Zia Ur Rahman Nigar Ali +4 位作者 Dragan Pamucar Imtiaz Ahmad Haci Mehmet Baskonus Naseer Ul Haq Zeeshan Ali 《Computer Modeling in Engineering & Sciences》 2026年第1期954-988,共35页
Hepatitis B Virus(HBV)infection and heavy alcohol consumption are the two primary pathogenic causes of liver cirrhosis.In this paper,we proposed a deterministic mathematical model and a logistic equation to investigat... Hepatitis B Virus(HBV)infection and heavy alcohol consumption are the two primary pathogenic causes of liver cirrhosis.In this paper,we proposed a deterministic mathematical model and a logistic equation to investigate the dynamics of liver cirrhosis progression as well as to explain the implications of variations in alcohol consumption on chronic hepatitis B patients,respectively.The intricate interactions between liver cirrhosis,recovery,and treatment dynamics are captured by the model.This study aims to show that alcohol consumption by Hepatitis B-infected individuals accelerates liver cirrhosis progression while treatment of acutely infected individuals reduces it.We proved that a unique solution of the proposed model exists,which is positive and bounded.Using the next-generation matrix approach,two basic reproductive numbers R_(A_(0))and R_(A_(max))are calculated to identify future recurrence.The equilibrium points are calculated,and both equilibria are proved locally and globally asymptotically stable when R_(0)is below and above one,respectively.It is shown that bifurcation exists at R_(0)=1 and a detailed proof for forward bifurcation is given.Furthermore,we performed the sensitivity analysis of the model parameters on R_(0).For the confirmation of analytical work,we performed numerical simulations,and the results indicate that the treatment and the inhibitory effects reduce the risk of developing liver cirrhosis in individuals,while heavy alcohol consumption accelerates markedly the liver cirrhosis progression in patients with chronic hepatitis B. 展开更多
关键词 Liver cirrhosis deterministic model saturated incidence rate STABILITY forward bifurcation
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Steering China’s High-Quality Growth
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作者 《China Today》 2026年第1期16-19,共4页
Chinese President Xi Jinping has guided China through a year of resilient growth via forward-looking reforms and innovation-driven transformation that is shaping the nation’s economic trajectory for 2026 and beyond.
关键词 forward looking reforms high quality growth STEERING resilient growth innovation driven transformation
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THOUGHTS FOR A NEW ERA SELECTED REMARKS OF CHINESE PRESIDENT XI JINPING
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《ChinAfrica》 2026年第3期6-6,共1页
President Xi Jinping,who is also the general secretary of the Communist Party of China(CPC)Central Committee,presided over the 24th group study session of the Political Bureau of the CPC Central Committee on 30 Januar... President Xi Jinping,who is also the general secretary of the Communist Party of China(CPC)Central Committee,presided over the 24th group study session of the Political Bureau of the CPC Central Committee on 30 January.The session focused on the forward-looking planning and development of industries of the future.Edited excerpts of his speech follow. 展开更多
关键词 development forward looking planning political bureau Communist Party China Chinese President Xi Jinping future industries
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Application of physics-informed neural networks in solving temperature diffusion equation of seawater
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作者 Lei HAN Changming DONG +3 位作者 Yuli LIU Huarong XIE Hongchun ZHANG Weijun ZHU 《Journal of Oceanology and Limnology》 2026年第1期1-18,共18页
Physics-informed neural networks(PINNs),as a novel artificial intelligence method for solving partial differential equations,are applicable to solve both forward and inverse problems.This study evaluates the performan... Physics-informed neural networks(PINNs),as a novel artificial intelligence method for solving partial differential equations,are applicable to solve both forward and inverse problems.This study evaluates the performance of PINNs in solving the temperature diffusion equation of the seawater across six scenarios,including forward and inverse problems under three different boundary conditions.Results demonstrate that PINNs achieved consistently higher accuracy with the Dirichlet and Neumann boundary conditions compared to the Robin boundary condition for both forward and inverse problems.Inaccurate weighting of terms in the loss function can reduce model accuracy.Additionally,the sensitivity of model performance to the positioning of sampling points varied between different boundary conditions.In particular,the model under the Dirichlet boundary condition exhibited superior robustness to variations in point positions during the solutions of inverse problems.In contrast,for the Neumann and Robin boundary conditions,accuracy declines when points were sampled from identical positions or at the same time.Subsequently,the Argo observations were used to reconstruct the vertical diffusion of seawater temperature in the north-central Pacific for the applicability of PINNs in the real ocean.The PINNs successfully captured the vertical diffusion characteristics of seawater temperature,reflected the seasonal changes of vertical temperature under different topographic conditions,and revealed the influence of topography on the temperature diffusion coefficient.The PINNs were proved effective in solving the temperature diffusion equation of seawater with limited data,providing a promising technique for simulating or predicting ocean phenomena using sparse observations. 展开更多
关键词 temperature diffusion equation physics-informed neural network(PINN) boundary condition forward and inverse problem
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Cognitive NFIDC-FRBFNN Control Architecture for Robust Path Tracking of Mobile Service Robots in Hospital Settings
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作者 Huda Talib Najm Ahmed Sabah Al-Araji Nur Syazreen Ahmad 《Computer Modeling in Engineering & Sciences》 2026年第1期989-1022,共34页
Mobile service robots(MSRs)in hospital environments require precise and robust trajectory tracking to ensure reliable operation under dynamic conditions,including model uncertainties and external disturbances.This stu... Mobile service robots(MSRs)in hospital environments require precise and robust trajectory tracking to ensure reliable operation under dynamic conditions,including model uncertainties and external disturbances.This study presents a cognitive control strategy that integrates a Numerical Feedforward Inverse Dynamic Controller(NFIDC)with a Feedback Radial Basis Function Neural Network(FRBFNN).The robot’s mechanical structure was designed in SolidWorks 2022 SP2.0 and validated under operational loads using finite element analysis in ANSYS 2022 R1.The NFIDC-FRBFNN framework merges proactive inverse dynamic compensation with adaptive neural learning to achieve smooth torque responses and accurate motion control.A two-stage simulation evaluation was conducted.In the first stage,the controller was tested in a simulated hospital environment under both ideal and non-ideal conditions.In the second,it was benchmarked against four established controllers-Neural Network Model Reference Adaptive(NNMRA),Z-number Fuzzy Logic(Z-FL),Adaptive Dynamic Controller(ADC),and Fuzzy Logic-PID(FL-PID)—using circular and lemniscate trajectories.Across ten runs,the proposed controller achieved the lowest tracking errors under all conditions.Under ideal conditions,it achieved average improvements of 55.24%,75.75%,and 55.20%in integral absolute error(IAE),integral squared error(ISE),and mean absolute error(MAE),respectively,with coefficient of variation(CV)reductions above 55%.Under non-ideal conditions,average improvements exceeded 64%in IAE,77%in ISE,and 66%in MAE,while maintaining CV reductions above 57%.These results confirm that the NFIDC-FRBFNN controller offers superior accuracy,robustness,and consistency for real-time path tracking in healthcare robotics. 展开更多
关键词 Mobile service robot path planning radial basis function neural network trajectory tracking numerical feed forward inverse dynamic controller
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关于PBX正向设计的初步思考
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作者 张朝阳 黄鑫 谢炜宇 《含能材料》 北大核心 2025年第10期1135-1137,共3页
1.正向设计的概念及其在材料研发中的应用正向设计(Forward Design)是一种系统化的设计方法论,其核心在于从用户需求和预期功能出发,通过综合考虑性能、成本、制造工艺等因素,自上而下地进行产品设计和材料选择。这种方法强调在设计初... 1.正向设计的概念及其在材料研发中的应用正向设计(Forward Design)是一种系统化的设计方法论,其核心在于从用户需求和预期功能出发,通过综合考虑性能、成本、制造工艺等因素,自上而下地进行产品设计和材料选择。这种方法强调在设计初期就对产品的整体性能和各个组成部分进行综合考虑,以确保最终产品能够满足预定的性能标准和市场需求。 展开更多
关键词 材料研发 Forward Design 正向设计 成本
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CGA-Based Approach to Forward Kinematics of Parallel Mechanisms with the 3-RE Structure 被引量:2
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作者 Duanling Li Yuankai Zhang +4 位作者 Ying Zhang Zhonghai Zhang Longjie Fan Xiao Su Shuaimin Gao 《Chinese Journal of Mechanical Engineering》 2025年第3期365-376,共12页
To investigate the forward kinematics problem of parallel mechanisms with complex limbs and to expand the applicability of the powerful tool of Conformal Geometric Algebra(CGA),a CGA-based modeling and solution method... To investigate the forward kinematics problem of parallel mechanisms with complex limbs and to expand the applicability of the powerful tool of Conformal Geometric Algebra(CGA),a CGA-based modeling and solution method for a class of parallel platforms with 3-RE structure after locking the actuated joints is proposed in this paper.Given that the angle between specific joint axes of limbs remains constant,a set of geometric constraints for the forward kinematics of parallel mechanisms(PM)are determined.After translating unit direction vectors of these joint axes to the common starting point,the geometric constraints of the angle between the vectors are transformed into the distances between the endpoints of the vectors,making them easier to handle.Under the framework of CGA,the positions of key points that determine the position and orientation of the moving platform can be intuitively determined by the intersection,division,and duality of basic geometric entities.By employing the tangent half-angle substitution,the forward kinematic analysis of the parallel mechanisms leads to a high-order univariate polynomial equation without the need for any complex algebraic elimination operations.After solving this equation and back substitution,the position and pose of the MP can be obtained indirectly.A numerical case is utilized to confirm the effectiveness of the proposed method. 展开更多
关键词 Conformal geometric algebra Parallel mechanisms Forward kinematics Elimination-free Coordinate-
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Stratigraphic Forward Modeling of Late Quaternary Fluvial Dynamics in the Indus River Delta, Pakistan: Insights into Sea Level-Driven Sedimentary Evolution 被引量:1
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作者 HASSAN Hafiz Ahmed Raza LIU Keyu +3 位作者 LIU Jianliang MUNAWAR Muhammad Jawad REHMAN Saif Ur HUSSAIN Abid 《Journal of Ocean University of China》 2025年第6期1500-1518,共19页
Fluvial systems play a crucial role in coastal and riverine ecosystems, making it essential to understand their responses to sea level changes for preserving biodiversity and managing natural resources. The evolution ... Fluvial systems play a crucial role in coastal and riverine ecosystems, making it essential to understand their responses to sea level changes for preserving biodiversity and managing natural resources. The evolution of the modern Indus River Delta offers a rare opportunity to study the interplay between sea level fluctuations, tectonism, sediment supply, and the corresponding fluvial responses. This study employs the ‘SedSim' stratigraphic forward model to simulate the delta's evolution from 200 kyr to the next5 kyr, drawing on data from field observations, Landsat imagery, digital elevation models, and previous studies. The model consists of 205 layers, each representing a 1-kyr time step, covering the last two glacial-interglacial cycles. Between 200 kyr and 130 kyr, during a lowstand period, sedimentation on the delta plain continued due to partial flow from the Indus River. During the last interglacial(130–60 kyr), rising sea levels led to peak sediment deposition, characteristic of a highstand phase. From 60 kyr to 18 kyr, sea levels dropped to their lowest during the Last Glacial Maximum(LGM), resulting in extensive erosion and minimal deposition on the delta plain. From 18 kyr to the present, rapidly rising sea levels, coupled with intensified monsoon activity, increased sedimentation rates and triggered avulsion and aggradation processes. The model accurately predicted depositional thickness across the delta plain, indicating a maximum of ca. 200 m at the shoreline platform, ca. 175 m in the northeastern delta, and ca. 100 m in the central delta. The study underscores the delta's vulnerability to future sea level rise, which–at a projected rate of 1 m/kyr–could significantly influence the densely populated, low-lying delta plain. These findings offer valuable insights into the geomorphic evolution of the Indus Delta and emphasize the socioeconomic implications of sea level change, underscoring the importance of proactive management and adaptation strategies. 展开更多
关键词 fluvial responses sea level changes glacial-interglacial cycle sedimentary evolution stratigraphic forward modeling Indus Delta
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Sensitivity analysis of the lithospheric magnetic field at satellite altitude:the effects of the inducing field and the shape of the magnetic lithosphere 被引量:1
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作者 JinSong Du YuKun Li +5 位作者 HouPu Li ChangQing Yuan KangAn Zhao JiangSong Gui Pan Zhang ShaoFeng Bian 《Earth and Planetary Physics》 2025年第3期642-652,共11页
As a means of quantitative interpretation,forward calculations of the global lithospheric magnetic field in the Spherical Harmonic(SH)domain have been widely used to reveal geophysical,lithological,and geothermal vari... As a means of quantitative interpretation,forward calculations of the global lithospheric magnetic field in the Spherical Harmonic(SH)domain have been widely used to reveal geophysical,lithological,and geothermal variations in the lithosphere.Traditional approaches either do not consider the non-axial dipolar terms of the inducing field and its radial variation or do so by means of complicated formulae.Moreover,existing methods treat the magnetic lithosphere either as an infinitesimally thin layer or as a radially uniform spherical shell of constant thickness.Here,we present alternative forward formulae that account for an arbitrarily high maximum degree of the inducing field and for a magnetic lithosphere of variable thickness.Our simulations based on these formulae suggest that the satellite magnetic anomaly field is sensitive to the non-axial dipolar terms of the inducing field but not to its radial variation.Therefore,in forward and inverse calculations of satellite magnetic anomaly data,the non-axial dipolar terms of the inducing field should not be ignored.Furthermore,our results show that the satellite magnetic anomaly field is sensitive to variability in the lateral thickness of the magnetized shell.In particular,we show that for a given vertically integrated susceptibility distribution,underestimating the thickness of the magnetic layer overestimates the induced magnetic field.This discovery bridges the greatest part of the alleged gap between the susceptibility values measured from rock samples and the susceptibility values required to match the observed magnetic field signal.We expect the formulae and conclusions of this study to be a valuable tool for the quantitative interpretation of the Earth's global lithospheric magnetic field,through an inverse or forward modelling approach. 展开更多
关键词 lithospheric magnetic field forward calculation spherical harmonic analysis sensitivity analysis satellite magnetism
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Temperature and acoustic impedance simultaneous sensor based on forward stimulated Brillouin scattering in highly nonlinear fiber 被引量:1
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作者 Shilong Liu Yang Li +2 位作者 Hongbin Hu Bing Sun Zuxing Zhang 《Chinese Physics B》 2025年第7期394-400,共7页
A temperature and acoustic impedance simultaneous sensor based on forward stimulated Brillouin scattering(FSBS)in highly nonlinear fiber(HNLF)with high sensitivity and high accuracy is proposed and demonstrated in thi... A temperature and acoustic impedance simultaneous sensor based on forward stimulated Brillouin scattering(FSBS)in highly nonlinear fiber(HNLF)with high sensitivity and high accuracy is proposed and demonstrated in this paper.High-order acoustic modes(HOAMs)are used to achieve individual or simultaneous measurement of the two parameters.Transverse acoustic waves(TAWs)involved in the FSBS process can efficiently sense the mechanical or environmental changes outside the fiber cladding,which will be reflected in a linear shift of the acoustic resonance frequency.By analyzing the frequencies of specific scattering peaks,the temperature and acoustic impedance outside the fiber cladding can be obtained simultaneously.The highest measured temperature and acoustic impedance sensitivities are 184.93 k Hz/℃and444.56 k Hz/MRayl,and the measurement accuracies are 0.09℃and 0.009 MRayl,respectively,which are both at desirable levels.We believe this work can provide potential application solutions for sensing fields involving temperature or acoustic impedance measurements. 展开更多
关键词 forward stimulated Brillouin scattering(FSBS) fiber optic sensor temperature sensor acoustic impedance sensor simultaneous measurement
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A novel approach to visual image encryption:2D hyperchaos,variable Josephus,and 3D diffusion 被引量:1
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作者 Yan Hong Xinyan Duan +2 位作者 Jingming Su Zhaopan Wang Shihui Fang 《Chinese Physics B》 2025年第4期335-352,共18页
With the development of the Internet,image encryption technology has become critical for network security.Traditional methods often suffer from issues such as insufficient chaos,low randomness in key generation,and po... With the development of the Internet,image encryption technology has become critical for network security.Traditional methods often suffer from issues such as insufficient chaos,low randomness in key generation,and poor encryption efficiency.To enhance performance,this paper proposes a new encryption algorithm designed to optimize parallel processing and adapt to images of varying sizes and colors.The method begins by using SHA-384 to extract the hash value of the plaintext image,which is then processed to determine the chaotic system’s initial value and block size.The image is padded and divided into blocks for further processing.A novel two-dimensional infinite collapses hyperchaotic map(2DICHM)is employed to generate the intra-block scrambling sequence,while an improved variable Joseph traversal sequence is used for inter-block scrambling.After removing the padding,3D forward and backward shift diffusions,controlled by the 2D-ICHM sequences,are applied to the scrambled image,producing the ciphertext.Simulation results demonstrate that the proposed algorithm outperforms others in terms of entropy,anti-noise resilience,correlation coefficient,robustness,and encryption efficiency. 展开更多
关键词 SHA-384 two-dimensional infinite collapses hyperchaotic map(2D-ICHM) variable Joseph traversal 3D forward shift diffusion
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CPIFA Visits & Events (April-June)
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《Foreign Affairs Journal》 2025年第2期110-152,共43页
Wang Yi Delivers Speech to the Roundtable on Carrying Forward the Bandung Spirit On April 17,2025,Member of the Political Bureau of the CPC Central Committee and Foreign Minister Wang Yi delivered a written speech to ... Wang Yi Delivers Speech to the Roundtable on Carrying Forward the Bandung Spirit On April 17,2025,Member of the Political Bureau of the CPC Central Committee and Foreign Minister Wang Yi delivered a written speech to the Roundtable themed "The Global South:Carrying Forward the Bandung Spirit and Marching Together toward Modernization". 展开更多
关键词 MODERNIZATION bandung spirit carrying forward bandung spirit speech global south forward bandung spirit roundtable
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Modification of texture in AZ31 magnesium alloy via cold pre-upsetting alternating forward extrusion
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作者 Shun Luo Feng Li +2 位作者 Yuan Qi Li Hai Bo Wang Jia Yang Zhang 《Journal of Magnesium and Alloys》 2025年第12期6183-6194,共12页
Prefabricated twinning represents an effective strategy for optimizing the microstructure of extruded forming components and facilitating changes in texture.The study examines the incorporation of[10-12]twins into an ... Prefabricated twinning represents an effective strategy for optimizing the microstructure of extruded forming components and facilitating changes in texture.The study examines the incorporation of[10-12]twins into an AZ31 magnesium alloy billet via cold pre-upsetting deformation before alternating forward extrusion(CUAFE).The experimental results indicate that the initial presence of[10-12]twins is advantageous for the development of[10-10]and[11-20]texture components during the extrusion process.In addition,different DRX mechanisms have different influences on the evolution of basal texture.The CDRX grains tend to preferentially select the[11-20]texture orientation,weakening the[10-10]texture and enhancing the[11-20]texture.However,most DDRX grains deviate significantly from the orientation of their surrounding original grain and do not have a preferred orientation.This is reflected in the mechanical properties of the CUAFE part.The tensile strength is 323.5 MPa,while the elongation is as high as 20.1%. 展开更多
关键词 Alternating forward extrusion Pre-upsetting TWINNING RECRYSTALLIZATION TEXTURE
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Rab11 participated in the chronic effect of AngII on the IKs current and KCNQ1 channel protein expression
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作者 Xin-Ru Zhao Chen-Yue Shao +2 位作者 Yun-Sheng Xu Huan Zhang Xiang-Bo Gou 《Biomedical Engineering Communications》 2025年第2期56-62,共7页
Background:The decreased slowly activating delayed rectifier K+current(IKs)is the molecular basis of arrhythmia caused by myocardial hypertrophy.The aim of this study was to investigate the mechanism of IKs down-regul... Background:The decreased slowly activating delayed rectifier K+current(IKs)is the molecular basis of arrhythmia caused by myocardial hypertrophy.The aim of this study was to investigate the mechanism of IKs down-regulation related to the channel number,as well as the regulation of channel number under pathological conditions.Methods:The HEK 293 cell co-transfected with KCNQ1/KCNE1 genes was cultured conventionally.After the cells incubated with angiotensin II(AngII)(24 h),AngII(72 h),bisindolylmaleimide I(Bis),brefeldin A and dynasore,the effect and relevant mechanism of long term incubation of AngII on the IKs tail current and KCNQ1 channel total protein were investigated by electrophysiology method and western blotting.In the experiment,the Bis,brefeldin A and dynasore could inhibit the protein kinase C(PKC)activity,the forward transport of KCNQ1 channel and the endocytosis of KCNQ1 channel,respectively.At last,the Rab GTPases 11(Rab11)dominant-negative mutant dsRed-Rab11/S25N was infected into the cells to investigate the effect and relevant mechanism of long term AngII incubation on the IKs tail current and KCNQ1 channel total protein.Results:Our results showed that the decreased IKs tail current and the KCNQ1 channel total protein caused by long term AngII incubation were attenuated by Bis treatment,which inhibited PKC activity.In addition,the inhibited IKs tail current and KCNQ1 channel total protein were also alleviated by brefeldin A and dynasore treatment.At last,the expression of Rab11 dominant-negative mutant dsRed-Rab11/S25N could weak the inhibition of IKs tail current and the KCNQ1 channel total protein caused by long term AngII incubation.Conclusion:The long term incubation of AngII inhibited the IKs tail current and KCNQ1 channel total protein was achieved by PKC activation and the disorder of the channel trafficking by Rab11. 展开更多
关键词 IKS KCNQ1 forward transport ENDOCYTOSIS Rab11
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Lightweight design and manufacture of die casting magnesium alloy seat frame
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作者 Jian Yang Kangle Wang +3 位作者 Qin Yang Jinsheng Zhang Tiegang Hu Bo Liu 《Journal of Magnesium and Alloys》 2025年第10期4817-4824,共8页
This study presents the development of a Magnesium Alloy Seat Frame(MASF),supported by case studies from automotive original equipment manufacturers.The process covers integrated design,simulation,manufacturing,and te... This study presents the development of a Magnesium Alloy Seat Frame(MASF),supported by case studies from automotive original equipment manufacturers.The process covers integrated design,simulation,manufacturing,and testing,aiming to boost industry confidence in Mg alloy applications.A novel structural design is developed that integrates the headrest with the backrest,achieving a balance between lightweight performance and safety.Structural optimization is guided by stress–strain simulations under diverse conditions within a complete forward development process.Casting simulations are conducted to analyze process characteristics,resulting in a verified MASF yield rate exceeding 90%.The final 9.88 kg MASF represents a 24.6%(3.23 kg)weight reduction versus a steel seat.This research contributes to advancements in defect control technology for large die casting magnesium alloy parts and has broad implications for their application in automotive manufacturing. 展开更多
关键词 MAGNESIUM Seat frame Forward design Die casting Lightweighting
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Speech at the Roundtable on Carrying Forward the Bandung Spirit
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作者 U Thant Kyaw 《Foreign Affairs Journal》 2025年第1期16-20,共5页
Today,we gather under the theme of"The Global South:Carrying Forward the Bandung Spirit and Marching together toward Modernization",which is a concept that impacts the complex global obstacles we face nowadays.
关键词 Bandung spirit global south forward bandung spirit global obstacles complex global obstacles MODERNIZATION
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Speech at the Roundtable on Carrying Forward the Bandung Spirit
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作者 Khrushid Mahmud Kasuri 《Foreign Affairs Journal》 2025年第1期10-15,共6页
I am very happy to be part of the"Roundtable on Carrying Forward the Bandung Spirit".It takes me down to the memory lane when I was just a college student,I remember the first PM of the People's Republic... I am very happy to be part of the"Roundtable on Carrying Forward the Bandung Spirit".It takes me down to the memory lane when I was just a college student,I remember the first PM of the People's Republic of China Chou En-Lai and first President of the Republic of Indonesia,Ahmed Sukarno,as great friends of Pakistan.Both paid historic visits to Pakistan,where they received overwhelming public enthusiasm. 展开更多
关键词 Pakistan Bandung Spirit Diplomatic Relations Historical Visits Public Enthusiasm China carrying forward bandung Indonesia
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