Objective To explore the diversity of stagnant effusions and the pathologic processes leading to granulation tissue formation in otitis media with effusion(OME). Methods Temporal bone slides from 306 ears with OME w...Objective To explore the diversity of stagnant effusions and the pathologic processes leading to granulation tissue formation in otitis media with effusion(OME). Methods Temporal bone slides from 306 ears with OME were studied histopathologically under the light microscope. Results Results of this study revealed a pathologic process in witch the type and the condition of stagnant effusion in the middle ear cleft was a variable in the dynamics of OME progression from an early stage to an advanced stage. The location of granulation tissue and retentive effusion were found to be closely related. Conclusion Early stage granulation tissue formation exhibited a pathologic process in which granulation tissue formation occurred only in areas where effusion had stagnated or was absorbed. The incidence of the retentive effusion and formation of granulation tissue was much higher and the pathologic changes most extensive in the area around the ossicular chain.展开更多
To study the transformation process of calcium phosphate bioceramic in vivo,biodegradable porous β-tricalcium phosphate ceramics (β-TCP) were used in this experiment. The materials (5×8mm) were implanted in the...To study the transformation process of calcium phosphate bioceramic in vivo,biodegradable porous β-tricalcium phosphate ceramics (β-TCP) were used in this experiment. The materials (5×8mm) were implanted in the tibia of rabbits. The β-TCP ceramics with bone tissue were retrieved and treated for histology, and then observed by using a scanning electron microscope (SEM) and an electron probe X-ray microanalyzer (EMPA) every month. The results show that β-TCP ceramics bond to bone directly,new bones are forming and maturing with materials continuous degrading,and the materials are nearly replaced by the formed bone finally.Parts of the materials were degraded,absorpted and recrystallized,the others dispersped on the cancellous bone and the Haversian lamella with an irregular arrangement incorporating in bone formation directly by remodeling structure.展开更多
“Yang promotes Qi transformation and Yin promotes forming”maintains the normal progress of human life activities,which is an important embodiment of human vitality.The dysfunction of“Yang promotes Qi transformation...“Yang promotes Qi transformation and Yin promotes forming”maintains the normal progress of human life activities,which is an important embodiment of human vitality.The dysfunction of“Yang promotes Qi transformation and Yin promotes forming”leads to the coagulation of pathological products such as phlegm and blood stasis in the breast meridian,resulting in the occurrence of acne mastitis.In clinical treatment,we should take“warm Yang to promote Qi transformation”as the treatment principle,and add or subtract according to the specific situation.展开更多
A new set of relative orbit elements (ROEs) is used to derive a new elliptical formation flying model in previous work. In-plane and out-of-plane relative motions can be completely decoupled, which benefits elliptical...A new set of relative orbit elements (ROEs) is used to derive a new elliptical formation flying model in previous work. In-plane and out-of-plane relative motions can be completely decoupled, which benefits elliptical formation design. In order to study the elliptical control strategy and perturbation effects, it is necessary to derive the inverse transformation of the relative state transition matrix based on relative orbit elements. Poisson bracket theory is used to obtain the linear transformations between the two representations: the relative orbit elements and the geocentric orbital frame. In this paper, the details of these transformations are presented.展开更多
Supposing carbon contents of ferrite phases in pearlite precipitating from austenite in multicomponent steel at temperature T and in Fe-C ystem at T' are the same the pearlite formation temperature diference, can ...Supposing carbon contents of ferrite phases in pearlite precipitating from austenite in multicomponent steel at temperature T and in Fe-C ystem at T' are the same the pearlite formation temperature diference, can be calculated from the FeX phase diagrams and the equilibrium temperature Al. Using Tp and Fe-C binary thermodynamic model, the driving forces for phase transformation from austenite to pearlite in multicomponent steels have been successfully calculated. Through the combination of simplified Zener and Hillert's model for pearlite growth with Johnson-Mehl equation, using data from known TTT diagrams, the interfacial energy parameter and activation energy for pearlite formation can be determined and expressed as functions of chemical composition in steels by regression analysis. The calculated starting curves of pearlitic transformation in some commercial steels agree well with the experimental data.展开更多
Geo-data is a foundation for the prediction and assessment of ore resources, so managing and making full use of those data, including geography database, geology database, mineral deposits database, aeromagnetics data...Geo-data is a foundation for the prediction and assessment of ore resources, so managing and making full use of those data, including geography database, geology database, mineral deposits database, aeromagnetics database, gravity database, geochemistry database and remote sensing database, is very significant. We developed national important mining zone database （NIMZDB） to manage 14 national important mining zone databases to support a new round prediction of ore deposit. We found that attention should be paid to the following issues： ① data accuracy： integrity, logic consistency, attribute, spatial and time accuracy; ② management of both attribute and spatial data in the same system;③ transforming data between MapGIS and ArcGIS; ④ data sharing and security; ⑤ data searches that can query both attribute and spatial data. Accuracy of input data is guaranteed and the search, analysis and translation of data between MapGIS and ArcGIS has been made convenient via the development of a checking data module and a managing data module based on MapGIS and ArcGIS. Using AreSDE, we based data sharing on a client/server system, and attribute and spatial data are also managed in the same system.展开更多
This study analyzes the cooperative coalition problem for formation scheduling based on incomplete information. A multi-agent cooperative coalition framework is developed to optimize the formation scheduling problem i...This study analyzes the cooperative coalition problem for formation scheduling based on incomplete information. A multi-agent cooperative coalition framework is developed to optimize the formation scheduling problem in a decentralized manner. The social class differentiation mech- anism and role-assuming mechanism are incorporated into the framework, which, in turn, ensures that the multi-agent system （MAS） evolves in the optimal direction. Moreover, a further differen- tiation pressure can be achieved to help MAS escape from local optima. A Bayesian coalition nego- tiation algorithm is constructed, within which the Harsanyi transformation is introduced to transform the coalition problem based on incomplete information to the Bayesian-equivalent coali- tion problem based on imperfect information. The simulation results suggest that the distribution of agents＇ expectations of other agents＇ unknown information approximates to the true distribution after a finite set of generations. The comparisons indicate that the MAS cooperative coalition algo- rithm produces a significantly better utility and possesses a more effective capability of escaping from local optima than the proposal-engaged marriage algorithm and the Simulated Annealing algorithm.展开更多
To ensure safe flight of multiple fixed-wing unmanned aerial vehicles(UAVs)formation,considering trajectory planning and formation control together,a leader trajectory planning method based on the sparse A*algorithm i...To ensure safe flight of multiple fixed-wing unmanned aerial vehicles(UAVs)formation,considering trajectory planning and formation control together,a leader trajectory planning method based on the sparse A*algorithm is introduced.Firstly,a formation controller based on prescribed performance theory is designed to control the transient and steady formation configuration,as well as the formation forming time,which not only can form the designated formation configuration but also can guarantee collision avoidance and terrain avoidance theoretically.Next,considering the constraints caused by formation controller on trajectory planning such as the safe distance,turn angle and step length,as well as the constraint of formation shape,a leader trajectory planning method based on sparse A^(*)algorithm is proposed.Simulation results show that the UAV formation can arrive at the destination safely with a short trajectory no matter keeping the formation or encountering formation transformation.展开更多
Larger amount of austenite could be retained in an intercritically heat-treated bainite- transformed steel. The elongation and the strength-ductility balance of the steel could be enhanced considerably due to strain-i...Larger amount of austenite could be retained in an intercritically heat-treated bainite- transformed steel. The elongation and the strength-ductility balance of the steel could be enhanced considerably due to strain-induced martensite transformation and transformation- induced plasticity (TRIP) of retained austenite. The effects of test temperature and strain rate on the mechanical properties and strain induced transformation behavior of retained austenite in the steel were investigated. Total elongation and strength-ductility balance of the specimen reached maximum when it strained at a strain rate of 2.8×10-4s-1 and at 350℃. The relation between test temperature and tensile properties showed the same tendency at three kinds of strain rates. Flow stress increased considerably with decreasing the strain rate.展开更多
Tissue engineering chambers (TECs) represent a new and attractive in vivo tissue engineering model that can successfully generate mature adipose tissue. However, the newly formed adipose tissue is not able to fill the...Tissue engineering chambers (TECs) represent a new and attractive in vivo tissue engineering model that can successfully generate mature adipose tissue. However, the newly formed adipose tissue is not able to fill the volume of the chamber as expected. To investigate whether the capsule surrounding the newly formed adipose tissue limits the adipose tissue volume in the chamber, we detected fibrotic parameters two months after these chambers were implanted into rats. The results showed that the newly formed adipose tissue was surrounded by a thick layer of capsule, and the protein levels of transforming growth factor-<em>β</em>1 (TGF-<em>β</em>1), phosphorylated Smad2 (p-Smad2), connective tissue growth factor (CTGF), collagen type I (COL-I) and α-smooth muscle actin (<em>α</em>-SMA) in the capsule were increased. The levels of these proteins decreased following systemic administration of P144 (a peptide inhibitor of TGF-<em>β</em>1). Furthermore, the capsule thickness was significantly reduced, and the adipose tissue volume was markedly greater when using P144. These findings indicate that capsule formation, which is mediated through a TGF-<em>β</em>1 signaling pathway, restricted the volume of the engineered adipose tissue that was formed. This study may provide a new approach to regenerate amounts of adipose tissue for the reconstruction of large soft tissue defects.展开更多
This paper proposes a novel inverse synthetic aperture radar（ISAR） imaging method based on second-order keystone transform（KT） and Sandglass transform for group targets flying in a formation with constant accelera...This paper proposes a novel inverse synthetic aperture radar（ISAR） imaging method based on second-order keystone transform（KT） and Sandglass transform for group targets flying in a formation with constant accelerated rectilinear motion in the same radar beam. First, range curvature and range walk of each sub-target among group targets are corrected by the second-order KT combined with the quadratic phase term compensation. After range alignment, the signals in each range frequency cell can be modelled as multiple chirp signals and then the Sandglass transform is utilized to cross-range imaging, which transforms the time–frequency distribution of the signals in each range frequency cell into beelines parallel to the slow time axis simultaneously. Finally, cross-range profiles of group targets in each range frequency cell are obtained via a projection of the perk of every scatterer in the two-dimensional accumulation plane onto the frequency axis. The advantage of the proposed method is that it can align range profiles of each sub-target simultaneously and image cross-range profiles directly without separating the returned signals, which simplifies the operation procedure. Simulation results are used to demonstrate the effectiveness of the proposed method.展开更多
In the Chinese character intelligent formation system without Chinese character library, it is possible that the same basic element in different Chinese characters is different in position, size and shape. The geometr...In the Chinese character intelligent formation system without Chinese character library, it is possible that the same basic element in different Chinese characters is different in position, size and shape. The geometry transformation from basic elements to the components of Chinese characters can be realized by affine transformation, the transformation knowledge acquisition is the premise of Chinese character intelligent formation. A novel algorithm is proposed to ac-quire the affine transformation knowledge of basic elements automatically in this paper. The interested region of Chi-nese character image is determined by the structure of the Chinese character. Scale invariant and location invariant of basic element and Chinese character image are extracted with SIFT features, the matching points of the two images are determined according to the principle of Minimum Euclidean distance of eigenvectors. Using corner points as identifi-cation features, calculating the one-way Hausdorff distance between corner points as the similarity measurement from the affine image to the Chinese character sub-image, affine coefficients are determined by optimal similarity. 70244 Chinese characters in National Standards GB18030-2005 character set are taken as the experimental object, all the characters are performed and the experimental courses and results are presented in this paper.展开更多
文摘Objective To explore the diversity of stagnant effusions and the pathologic processes leading to granulation tissue formation in otitis media with effusion(OME). Methods Temporal bone slides from 306 ears with OME were studied histopathologically under the light microscope. Results Results of this study revealed a pathologic process in witch the type and the condition of stagnant effusion in the middle ear cleft was a variable in the dynamics of OME progression from an early stage to an advanced stage. The location of granulation tissue and retentive effusion were found to be closely related. Conclusion Early stage granulation tissue formation exhibited a pathologic process in which granulation tissue formation occurred only in areas where effusion had stagnated or was absorbed. The incidence of the retentive effusion and formation of granulation tissue was much higher and the pathologic changes most extensive in the area around the ossicular chain.
文摘To study the transformation process of calcium phosphate bioceramic in vivo,biodegradable porous β-tricalcium phosphate ceramics (β-TCP) were used in this experiment. The materials (5×8mm) were implanted in the tibia of rabbits. The β-TCP ceramics with bone tissue were retrieved and treated for histology, and then observed by using a scanning electron microscope (SEM) and an electron probe X-ray microanalyzer (EMPA) every month. The results show that β-TCP ceramics bond to bone directly,new bones are forming and maturing with materials continuous degrading,and the materials are nearly replaced by the formed bone finally.Parts of the materials were degraded,absorpted and recrystallized,the others dispersped on the cancellous bone and the Haversian lamella with an irregular arrangement incorporating in bone formation directly by remodeling structure.
文摘“Yang promotes Qi transformation and Yin promotes forming”maintains the normal progress of human life activities,which is an important embodiment of human vitality.The dysfunction of“Yang promotes Qi transformation and Yin promotes forming”leads to the coagulation of pathological products such as phlegm and blood stasis in the breast meridian,resulting in the occurrence of acne mastitis.In clinical treatment,we should take“warm Yang to promote Qi transformation”as the treatment principle,and add or subtract according to the specific situation.
文摘A new set of relative orbit elements (ROEs) is used to derive a new elliptical formation flying model in previous work. In-plane and out-of-plane relative motions can be completely decoupled, which benefits elliptical formation design. In order to study the elliptical control strategy and perturbation effects, it is necessary to derive the inverse transformation of the relative state transition matrix based on relative orbit elements. Poisson bracket theory is used to obtain the linear transformations between the two representations: the relative orbit elements and the geocentric orbital frame. In this paper, the details of these transformations are presented.
文摘Supposing carbon contents of ferrite phases in pearlite precipitating from austenite in multicomponent steel at temperature T and in Fe-C ystem at T' are the same the pearlite formation temperature diference, can be calculated from the FeX phase diagrams and the equilibrium temperature Al. Using Tp and Fe-C binary thermodynamic model, the driving forces for phase transformation from austenite to pearlite in multicomponent steels have been successfully calculated. Through the combination of simplified Zener and Hillert's model for pearlite growth with Johnson-Mehl equation, using data from known TTT diagrams, the interfacial energy parameter and activation energy for pearlite formation can be determined and expressed as functions of chemical composition in steels by regression analysis. The calculated starting curves of pearlitic transformation in some commercial steels agree well with the experimental data.
基金This paper is financially supported by the National I mportant MiningZone Database ( No .200210000004)Prediction and Assessment ofMineral Resources and Social Service (No .1212010331402) .
文摘Geo-data is a foundation for the prediction and assessment of ore resources, so managing and making full use of those data, including geography database, geology database, mineral deposits database, aeromagnetics database, gravity database, geochemistry database and remote sensing database, is very significant. We developed national important mining zone database （NIMZDB） to manage 14 national important mining zone databases to support a new round prediction of ore deposit. We found that attention should be paid to the following issues： ① data accuracy： integrity, logic consistency, attribute, spatial and time accuracy; ② management of both attribute and spatial data in the same system;③ transforming data between MapGIS and ArcGIS; ④ data sharing and security; ⑤ data searches that can query both attribute and spatial data. Accuracy of input data is guaranteed and the search, analysis and translation of data between MapGIS and ArcGIS has been made convenient via the development of a checking data module and a managing data module based on MapGIS and ArcGIS. Using AreSDE, we based data sharing on a client/server system, and attribute and spatial data are also managed in the same system.
基金supported by the National Natural Science Foundation of China(No.61039001)the National Science and Technology Support Program of China(No.2011BAH24B10)
文摘This study analyzes the cooperative coalition problem for formation scheduling based on incomplete information. A multi-agent cooperative coalition framework is developed to optimize the formation scheduling problem in a decentralized manner. The social class differentiation mech- anism and role-assuming mechanism are incorporated into the framework, which, in turn, ensures that the multi-agent system （MAS） evolves in the optimal direction. Moreover, a further differen- tiation pressure can be achieved to help MAS escape from local optima. A Bayesian coalition nego- tiation algorithm is constructed, within which the Harsanyi transformation is introduced to transform the coalition problem based on incomplete information to the Bayesian-equivalent coali- tion problem based on imperfect information. The simulation results suggest that the distribution of agents＇ expectations of other agents＇ unknown information approximates to the true distribution after a finite set of generations. The comparisons indicate that the MAS cooperative coalition algo- rithm produces a significantly better utility and possesses a more effective capability of escaping from local optima than the proposal-engaged marriage algorithm and the Simulated Annealing algorithm.
基金supported by the National Natural Science Foundation of China(11502019).
文摘To ensure safe flight of multiple fixed-wing unmanned aerial vehicles(UAVs)formation,considering trajectory planning and formation control together,a leader trajectory planning method based on the sparse A*algorithm is introduced.Firstly,a formation controller based on prescribed performance theory is designed to control the transient and steady formation configuration,as well as the formation forming time,which not only can form the designated formation configuration but also can guarantee collision avoidance and terrain avoidance theoretically.Next,considering the constraints caused by formation controller on trajectory planning such as the safe distance,turn angle and step length,as well as the constraint of formation shape,a leader trajectory planning method based on sparse A^(*)algorithm is proposed.Simulation results show that the UAV formation can arrive at the destination safely with a short trajectory no matter keeping the formation or encountering formation transformation.
基金the National Natural Science Foundation of China(No.50334010)the Doctor Degree Thesis Subsidization Item of Northeastern Universiry(No.200302).
文摘Larger amount of austenite could be retained in an intercritically heat-treated bainite- transformed steel. The elongation and the strength-ductility balance of the steel could be enhanced considerably due to strain-induced martensite transformation and transformation- induced plasticity (TRIP) of retained austenite. The effects of test temperature and strain rate on the mechanical properties and strain induced transformation behavior of retained austenite in the steel were investigated. Total elongation and strength-ductility balance of the specimen reached maximum when it strained at a strain rate of 2.8×10-4s-1 and at 350℃. The relation between test temperature and tensile properties showed the same tendency at three kinds of strain rates. Flow stress increased considerably with decreasing the strain rate.
文摘Tissue engineering chambers (TECs) represent a new and attractive in vivo tissue engineering model that can successfully generate mature adipose tissue. However, the newly formed adipose tissue is not able to fill the volume of the chamber as expected. To investigate whether the capsule surrounding the newly formed adipose tissue limits the adipose tissue volume in the chamber, we detected fibrotic parameters two months after these chambers were implanted into rats. The results showed that the newly formed adipose tissue was surrounded by a thick layer of capsule, and the protein levels of transforming growth factor-<em>β</em>1 (TGF-<em>β</em>1), phosphorylated Smad2 (p-Smad2), connective tissue growth factor (CTGF), collagen type I (COL-I) and α-smooth muscle actin (<em>α</em>-SMA) in the capsule were increased. The levels of these proteins decreased following systemic administration of P144 (a peptide inhibitor of TGF-<em>β</em>1). Furthermore, the capsule thickness was significantly reduced, and the adipose tissue volume was markedly greater when using P144. These findings indicate that capsule formation, which is mediated through a TGF-<em>β</em>1 signaling pathway, restricted the volume of the engineered adipose tissue that was formed. This study may provide a new approach to regenerate amounts of adipose tissue for the reconstruction of large soft tissue defects.
基金supported by the National Natural Science Foundation of China (No. 61372159)
文摘This paper proposes a novel inverse synthetic aperture radar（ISAR） imaging method based on second-order keystone transform（KT） and Sandglass transform for group targets flying in a formation with constant accelerated rectilinear motion in the same radar beam. First, range curvature and range walk of each sub-target among group targets are corrected by the second-order KT combined with the quadratic phase term compensation. After range alignment, the signals in each range frequency cell can be modelled as multiple chirp signals and then the Sandglass transform is utilized to cross-range imaging, which transforms the time–frequency distribution of the signals in each range frequency cell into beelines parallel to the slow time axis simultaneously. Finally, cross-range profiles of group targets in each range frequency cell are obtained via a projection of the perk of every scatterer in the two-dimensional accumulation plane onto the frequency axis. The advantage of the proposed method is that it can align range profiles of each sub-target simultaneously and image cross-range profiles directly without separating the returned signals, which simplifies the operation procedure. Simulation results are used to demonstrate the effectiveness of the proposed method.
文摘In the Chinese character intelligent formation system without Chinese character library, it is possible that the same basic element in different Chinese characters is different in position, size and shape. The geometry transformation from basic elements to the components of Chinese characters can be realized by affine transformation, the transformation knowledge acquisition is the premise of Chinese character intelligent formation. A novel algorithm is proposed to ac-quire the affine transformation knowledge of basic elements automatically in this paper. The interested region of Chi-nese character image is determined by the structure of the Chinese character. Scale invariant and location invariant of basic element and Chinese character image are extracted with SIFT features, the matching points of the two images are determined according to the principle of Minimum Euclidean distance of eigenvectors. Using corner points as identifi-cation features, calculating the one-way Hausdorff distance between corner points as the similarity measurement from the affine image to the Chinese character sub-image, affine coefficients are determined by optimal similarity. 70244 Chinese characters in National Standards GB18030-2005 character set are taken as the experimental object, all the characters are performed and the experimental courses and results are presented in this paper.
