The form-B monodinic insulin crystal was obtained from the sodium citrate buffer with 1% zinc chloride, keeping phenolic content between 0.76% and 1.25%. Its space group is P21, cell constants are: a = 4.924nm, b=6.09...The form-B monodinic insulin crystal was obtained from the sodium citrate buffer with 1% zinc chloride, keeping phenolic content between 0.76% and 1.25%. Its space group is P21, cell constants are: a = 4.924nm, b=6.094nm, c=4.818nm, β=95.8°. There are 6 insulin molecules which form a hexamer. The initial phase was obtained by using rotation function program of X-PLOR program package and molecular packing program of our laboratory. The molecular model was chosen from 4 zinc bovine insulin hexamer. After the preliminary refinement by using the rnacromolecular rigid body refinement technique, the molecular model was further refined and adjusted by using the energy-minimizing stereochemically restrained least-squared refinement on the difference Fourier maps. The finial R-factor is 214% at 0.3nm resolution, the r.m.s. deviations from standard bond length and bond angle are 0.0022nm and 4.7°, respectively.展开更多
在新时代背景下,随着数字化技术的不断发展与工业化进程的不断提高,钢结构厂房在建造和管理等方面正面临新的机遇和挑战。传统钢结构厂房在建筑过程中的管理模式存在信息孤岛、沟通不畅等缺陷,造成大量的资源浪费,并对生态环境造成一定...在新时代背景下,随着数字化技术的不断发展与工业化进程的不断提高,钢结构厂房在建造和管理等方面正面临新的机遇和挑战。传统钢结构厂房在建筑过程中的管理模式存在信息孤岛、沟通不畅等缺陷,造成大量的资源浪费,并对生态环境造成一定的破坏,不符合当今的绿色发展要求。因此,本文以钢结构厂房为基础,利用BIM技术,借助数字化技术对数据精准的处理能力,提出协同管理体系。采用程序开发工具Visual Studio 2019创建Winform窗体,运用B/S、C/S架构搭建协同管理平台、优化管理步骤及提升管理效能。该平台与传统生产管理相比具有显著优势,研究结果可为其他建筑项目的管理平台设计提供借鉴。展开更多
基金Project supported by the Chinese Academy of Sciences.
文摘The form-B monodinic insulin crystal was obtained from the sodium citrate buffer with 1% zinc chloride, keeping phenolic content between 0.76% and 1.25%. Its space group is P21, cell constants are: a = 4.924nm, b=6.094nm, c=4.818nm, β=95.8°. There are 6 insulin molecules which form a hexamer. The initial phase was obtained by using rotation function program of X-PLOR program package and molecular packing program of our laboratory. The molecular model was chosen from 4 zinc bovine insulin hexamer. After the preliminary refinement by using the rnacromolecular rigid body refinement technique, the molecular model was further refined and adjusted by using the energy-minimizing stereochemically restrained least-squared refinement on the difference Fourier maps. The finial R-factor is 214% at 0.3nm resolution, the r.m.s. deviations from standard bond length and bond angle are 0.0022nm and 4.7°, respectively.
文摘在新时代背景下,随着数字化技术的不断发展与工业化进程的不断提高,钢结构厂房在建造和管理等方面正面临新的机遇和挑战。传统钢结构厂房在建筑过程中的管理模式存在信息孤岛、沟通不畅等缺陷,造成大量的资源浪费,并对生态环境造成一定的破坏,不符合当今的绿色发展要求。因此,本文以钢结构厂房为基础,利用BIM技术,借助数字化技术对数据精准的处理能力,提出协同管理体系。采用程序开发工具Visual Studio 2019创建Winform窗体,运用B/S、C/S架构搭建协同管理平台、优化管理步骤及提升管理效能。该平台与传统生产管理相比具有显著优势,研究结果可为其他建筑项目的管理平台设计提供借鉴。
