Objective The trial was designed to evaluate the safety and performance of the ev3 Protégé TM stent in the treatment of de novo or re-stenotic common and/or internal carotid artery stenoses with adjunctive u...Objective The trial was designed to evaluate the safety and performance of the ev3 Protégé TM stent in the treatment of de novo or re-stenotic common and/or internal carotid artery stenoses with adjunctive use of a CE-marked filter embolic protection device.Methods This study was a prospective multi-center, single-arm trial. Between June and October 2003, 77 patients were enrolled in 8 investigational centers throughout Europe. The primary endpoint was the incidence of Major Neurological Events (MANE) through one month. Other endpoints were the ability to properly place the stent, and primary patency and MANE after six months. Eligible for the study were patients with a de novo or restenotic target lesion located in the common and/or internal carotid artery (>70% stenosis for asymptomatic and >50% stenosis for symptomatic patients). The ev3 Spider (Embolic Protection Filter was used in 75 of 77 cases. Results In 76 out of the 77 patients (99%), the stent could be successfully implanted with a residual stenosis ≤30% as criterion. Of the 74 patients that had a carotid ultrasound at one month follow-up, none had a re-stenosis of the target lesion. There were three MANEs during or immediately after the procedure (3.9%), two were major and one was a minor stroke. There were eight severe complications (9.1%); six of these happened during or immediately after the procedure and were related to the procedure, none was related to the device. They are resolved without sequelae. No deaths have occurred.Conclusions The Protégé stent is safe and performs well in the treatment of carotid artery stenosis. The technical success rate for placement of the Protégé stent as assessed by the residual stenosis post implant was very high and all stents were successfully deployed. The incidence of MANE was comparable with that in other recent carotid stent studies and still lower than standard CEA.展开更多
In this paper, we design and fabricate a silicon integrated optical filter consisting of two cascaded micro-ring resonators and two straight waveguides. Two micro-heaters are fabricated on the top of two micro-rings r...In this paper, we design and fabricate a silicon integrated optical filter consisting of two cascaded micro-ring resonators and two straight waveguides. Two micro-heaters are fabricated on the top of two micro-rings respectively, which are employed to modulate the micro-rings to perform the function of a tunable optical filter by the thermo–optic effect. The static response test indicates that the extinction ratio and 3-d B bandwidth are 29.01 d B and 0.21 nm respectively, the dynamic response test indicates that the 10%–90% rise and 90%–10% fall time of the filter are 16 μs and 12 μs, respectively,which can meet the requirements of optical communication and information processing. Finally, the power consumption of the device is also characterized, and the total power consumption is about 9.43 m W/nm, which has been improved efficiently.展开更多
The design, production and characterization of tailored printable optical filters for visible optical communications are demonstrated. As result, the average color difference between the specified and the produced fil...The design, production and characterization of tailored printable optical filters for visible optical communications are demonstrated. As result, the average color difference between the specified and the produced filters is 32.6, quantified in terms of CIELAB coordinates.展开更多
To settle the indicators of air pollutions at the industrial enterprises is very important. For this purpose, authors analyzed and developed a program for monitoring atmospheric composition in Borland Delphi 7 for the...To settle the indicators of air pollutions at the industrial enterprises is very important. For this purpose, authors analyzed and developed a program for monitoring atmospheric composition in Borland Delphi 7 for the calculation of the hazard class and the average daily maximum allowable concentration of air. Results of calculations on this program will allow operating composition of air by regulation of operating modes of filtering devices.展开更多
For the performance issues of satellite transceivers suffering passive intermodulation interference,a novel and effective digital suppression algorithm is presented in this paper.In contrast to analog approaches,digit...For the performance issues of satellite transceivers suffering passive intermodulation interference,a novel and effective digital suppression algorithm is presented in this paper.In contrast to analog approaches,digital passive intermodulation（PIM） suppression approaches can be easily reconfigured and therefore are highly attractive for future satellite communication systems.A simplified model of nonlinear distortion from passive microwave devices is established in consideration of the memory effect.The multiple high-order PIM products falling into the receiving band can be described as a bilinear predictor function.A suppression algorithm based on a bilinear polynomial decorrelated adaptive filter is proposed for baseband digital signal processing.In consideration of the time-varying characteristics of passive intermodulation,this algorithm can achieve the rapidness of online interference estimation and low complexity with less consumption of resources.Numerical simulation results show that the algorithm can effectively compensate the passive intermodulation interference,and achieve a high signal-to-interference ratio gain.展开更多
We provide an overview of our recent work on developing subwavelength grating （SWG） waveguide devices as an enabling technology for integrated microwave photonics. First, we describe wavelength-selective SWG wavegui...We provide an overview of our recent work on developing subwavelength grating （SWG） waveguide devices as an enabling technology for integrated microwave photonics. First, we describe wavelength-selective SWG waveguide filters, including ring resonators, Bragg gratings, and contradirectional couplers. Second, we discuss the development of an index variable optical true time delay line that exploits spatial diversity in an equal-length waveguide array. These SWG waveguide components are fundamental building blocks for realizing more complex structures for advanced microwave photonic signal processing.展开更多
We present the first experimental realization of a light spectral filter based on the spatial adiabatic passage technique.We demonstrate that a fully integrable CMOS-compatible system of three coupled identical total ...We present the first experimental realization of a light spectral filter based on the spatial adiabatic passage technique.We demonstrate that a fully integrable CMOS-compatible system of three coupled identical total internal reflection silicon oxide waveguides with variable separation along their propagation direction can be used simultaneously as a low-and high-pass spectral filter within the visible range of wavelengths.Light is injected into the right waveguide,and after propagating along the system,long wavelengths are transferred into the left output,whereas short wavelengths propagate to the right and central outputs.The stopband reaches values up to 211 dB for the left output and approximately 220 dB for the right plus central outputs.The passband values are close to 0 dB for both cases.We also demonstrate that the filtering characteristics of the device can be controlled by modifying the parameter values,which define the geometry of the triple-waveguide system.However,the general filtering behavior of the system does not critically depend on technological variations.Thus,the spatial adiabatic passage filtering approach constitutes an alternative to other integrated filtering devices,such as interference or absorbance-based filters.展开更多
In this paper, we theoretically propose and experimentally demonstrate the manipulation of a novel degree of freedom in ring resonators, which is the coupling from the clockwise input to the counterclockwise propagati...In this paper, we theoretically propose and experimentally demonstrate the manipulation of a novel degree of freedom in ring resonators, which is the coupling from the clockwise input to the counterclockwise propagating mode （and vice versa）. We name this mechanism backcoupling, in contrast with the normal forward-coupling of a directional coupler. It is well known that internal reflections will cause previous research demonstrated that the peak asymmetry will be strongly influenced by the backcoupling. Thus, it is worth manipulating the backcoupling in order to gain full control of a split resonance for the benefit of various resonance-splitting-based applications. While it is difficult to directly manipulate the backcoupling of a conventional directional coupler, here we design a circuit explicidy for manipulating the backcoupling. It can be potentially developed for applications such as single sideband filter, resonance splitting elimination, Fano resonance, and ultrahigh-Q and finesse.展开更多
In this paper, a novel modeling and simulation method for general linear, time-invariant, passive photonic devices and circuits is proposed. This technique, starting from the scattering parameters of the photonic syst...In this paper, a novel modeling and simulation method for general linear, time-invariant, passive photonic devices and circuits is proposed. This technique, starting from the scattering parameters of the photonic system under study, builds a baseband equivalent state-space model that splits the optical carrier frequency and operates at baseband, thereby significantly reducing the modeling and simulation complexity without losing accuracy.Indeed, it is possible to analytically reconstruct the port signals of the photonic system under study starting from the time-domain simulation of the corresponding baseband equivalent model. However, such equivalent models are complex-valued systems and, in this scenario, the conventional passivity constraints are not applicable anymore. Hence, the passivity constraints for scattering parameters and state-space models of baseband equivalent systems are presented, which are essential for time-domain simulations. Three suitable examples demonstrate the feasibility, accuracy, and efficiency of the proposed method.展开更多
文摘Objective The trial was designed to evaluate the safety and performance of the ev3 Protégé TM stent in the treatment of de novo or re-stenotic common and/or internal carotid artery stenoses with adjunctive use of a CE-marked filter embolic protection device.Methods This study was a prospective multi-center, single-arm trial. Between June and October 2003, 77 patients were enrolled in 8 investigational centers throughout Europe. The primary endpoint was the incidence of Major Neurological Events (MANE) through one month. Other endpoints were the ability to properly place the stent, and primary patency and MANE after six months. Eligible for the study were patients with a de novo or restenotic target lesion located in the common and/or internal carotid artery (>70% stenosis for asymptomatic and >50% stenosis for symptomatic patients). The ev3 Spider (Embolic Protection Filter was used in 75 of 77 cases. Results In 76 out of the 77 patients (99%), the stent could be successfully implanted with a residual stenosis ≤30% as criterion. Of the 74 patients that had a carotid ultrasound at one month follow-up, none had a re-stenosis of the target lesion. There were three MANEs during or immediately after the procedure (3.9%), two were major and one was a minor stroke. There were eight severe complications (9.1%); six of these happened during or immediately after the procedure and were related to the procedure, none was related to the device. They are resolved without sequelae. No deaths have occurred.Conclusions The Protégé stent is safe and performs well in the treatment of carotid artery stenosis. The technical success rate for placement of the Protégé stent as assessed by the residual stenosis post implant was very high and all stents were successfully deployed. The incidence of MANE was comparable with that in other recent carotid stent studies and still lower than standard CEA.
基金Project supported by the National Natural Science Foundation of China(Grant No.61405082)the Fundamental Research Funds for the Central Universities
文摘In this paper, we design and fabricate a silicon integrated optical filter consisting of two cascaded micro-ring resonators and two straight waveguides. Two micro-heaters are fabricated on the top of two micro-rings respectively, which are employed to modulate the micro-rings to perform the function of a tunable optical filter by the thermo–optic effect. The static response test indicates that the extinction ratio and 3-d B bandwidth are 29.01 d B and 0.21 nm respectively, the dynamic response test indicates that the 10%–90% rise and 90%–10% fall time of the filter are 16 μs and 12 μs, respectively,which can meet the requirements of optical communication and information processing. Finally, the power consumption of the device is also characterized, and the total power consumption is about 9.43 m W/nm, which has been improved efficiently.
基金The financial support of“Scientific and technological collaboration Portugal/China 2010/2012.Proc.0 441.00”is gratefully acknowledged.
文摘The design, production and characterization of tailored printable optical filters for visible optical communications are demonstrated. As result, the average color difference between the specified and the produced filters is 32.6, quantified in terms of CIELAB coordinates.
文摘To settle the indicators of air pollutions at the industrial enterprises is very important. For this purpose, authors analyzed and developed a program for monitoring atmospheric composition in Borland Delphi 7 for the calculation of the hazard class and the average daily maximum allowable concentration of air. Results of calculations on this program will allow operating composition of air by regulation of operating modes of filtering devices.
基金supported by the National Natural SciencFoundation of China(Nos.U1636125,61601027)
文摘For the performance issues of satellite transceivers suffering passive intermodulation interference,a novel and effective digital suppression algorithm is presented in this paper.In contrast to analog approaches,digital passive intermodulation（PIM） suppression approaches can be easily reconfigured and therefore are highly attractive for future satellite communication systems.A simplified model of nonlinear distortion from passive microwave devices is established in consideration of the memory effect.The multiple high-order PIM products falling into the receiving band can be described as a bilinear predictor function.A suppression algorithm based on a bilinear polynomial decorrelated adaptive filter is proposed for baseband digital signal processing.In consideration of the time-varying characteristics of passive intermodulation,this algorithm can achieve the rapidness of online interference estimation and low complexity with less consumption of resources.Numerical simulation results show that the algorithm can effectively compensate the passive intermodulation interference,and achieve a high signal-to-interference ratio gain.
基金supported in part by the Natural Sciences and Engineering Research Council of Canadathe Fonds de Recherche du Québec-Nature et Technologies,and the Royal Society
文摘We provide an overview of our recent work on developing subwavelength grating （SWG） waveguide devices as an enabling technology for integrated microwave photonics. First, we describe wavelength-selective SWG waveguide filters, including ring resonators, Bragg gratings, and contradirectional couplers. Second, we discuss the development of an index variable optical true time delay line that exploits spatial diversity in an equal-length waveguide array. These SWG waveguide components are fundamental building blocks for realizing more complex structures for advanced microwave photonic signal processing.
基金This work was supported by the Spanish Ministerio de Ciencia e Innovacion under contracts FIS2008-02425,FIS2011-23719 and CSD2006-0019by the Catalan Government under contract SGR2009-00347+1 种基金R Menchon-Enrich acknowledges the support received from the Spanish Ministerio de Educacion under grant AP2008-01276Funding from the European Research Council under the European Community’s Seventh Framework Programme(FP7/2007-2013)/ERC grant agreement number 209243 is also acknowledged.
文摘We present the first experimental realization of a light spectral filter based on the spatial adiabatic passage technique.We demonstrate that a fully integrable CMOS-compatible system of three coupled identical total internal reflection silicon oxide waveguides with variable separation along their propagation direction can be used simultaneously as a low-and high-pass spectral filter within the visible range of wavelengths.Light is injected into the right waveguide,and after propagating along the system,long wavelengths are transferred into the left output,whereas short wavelengths propagate to the right and central outputs.The stopband reaches values up to 211 dB for the left output and approximately 220 dB for the right plus central outputs.The passband values are close to 0 dB for both cases.We also demonstrate that the filtering characteristics of the device can be controlled by modifying the parameter values,which define the geometry of the triple-waveguide system.However,the general filtering behavior of the system does not critically depend on technological variations.Thus,the spatial adiabatic passage filtering approach constitutes an alternative to other integrated filtering devices,such as interference or absorbance-based filters.
文摘In this paper, we theoretically propose and experimentally demonstrate the manipulation of a novel degree of freedom in ring resonators, which is the coupling from the clockwise input to the counterclockwise propagating mode （and vice versa）. We name this mechanism backcoupling, in contrast with the normal forward-coupling of a directional coupler. It is well known that internal reflections will cause previous research demonstrated that the peak asymmetry will be strongly influenced by the backcoupling. Thus, it is worth manipulating the backcoupling in order to gain full control of a split resonance for the benefit of various resonance-splitting-based applications. While it is difficult to directly manipulate the backcoupling of a conventional directional coupler, here we design a circuit explicidy for manipulating the backcoupling. It can be potentially developed for applications such as single sideband filter, resonance splitting elimination, Fano resonance, and ultrahigh-Q and finesse.
基金Fonds Wetenschappelijk Onderzoek(FWO)(G013815N)Flanders Innovation&Entrepreneurship(VLAIO)Luceda Photonics through the MEPIC project
文摘In this paper, a novel modeling and simulation method for general linear, time-invariant, passive photonic devices and circuits is proposed. This technique, starting from the scattering parameters of the photonic system under study, builds a baseband equivalent state-space model that splits the optical carrier frequency and operates at baseband, thereby significantly reducing the modeling and simulation complexity without losing accuracy.Indeed, it is possible to analytically reconstruct the port signals of the photonic system under study starting from the time-domain simulation of the corresponding baseband equivalent model. However, such equivalent models are complex-valued systems and, in this scenario, the conventional passivity constraints are not applicable anymore. Hence, the passivity constraints for scattering parameters and state-space models of baseband equivalent systems are presented, which are essential for time-domain simulations. Three suitable examples demonstrate the feasibility, accuracy, and efficiency of the proposed method.
