Chikungunya virus(CHIKV),a medically significant arbovirus transmitted by Aedes mosquitoes,is the causative agent of chikungunya fever,characterized by severe and often prolonged arthralgia that imposes a substantial ...Chikungunya virus(CHIKV),a medically significant arbovirus transmitted by Aedes mosquitoes,is the causative agent of chikungunya fever,characterized by severe and often prolonged arthralgia that imposes a substantial public health burden worldwide[1].Over recent years,CHIKV outbreaks have increased in both frequency and geographic range,underscoring the need for enhanced genomic surveillance and rapid outbreak response.However,existing public repositories of CHIKV genomic data are frequently fragmented,incompletely annotated,and tied to inefficient analytical workflows,thereby limiting their utility in emergency settings.展开更多
基金supported by the National Key Research Program of China(grant number 2023YFC2306000 to G.F.)the Major Project of Guangzhou National Laboratory(grant number SRPG22007 to L.W.).
文摘Chikungunya virus(CHIKV),a medically significant arbovirus transmitted by Aedes mosquitoes,is the causative agent of chikungunya fever,characterized by severe and often prolonged arthralgia that imposes a substantial public health burden worldwide[1].Over recent years,CHIKV outbreaks have increased in both frequency and geographic range,underscoring the need for enhanced genomic surveillance and rapid outbreak response.However,existing public repositories of CHIKV genomic data are frequently fragmented,incompletely annotated,and tied to inefficient analytical workflows,thereby limiting their utility in emergency settings.