Due to using （R）- or （S）-a-methylbenzylamine as a chiral auxiliary, and low-temperature regime for reduction of the intermediate ferrocenyl-mono- or 1,1＇-bis-ketimines, the corresponding secondary mono- or 1,1＇-...Due to using （R）- or （S）-a-methylbenzylamine as a chiral auxiliary, and low-temperature regime for reduction of the intermediate ferrocenyl-mono- or 1,1＇-bis-ketimines, the corresponding secondary mono- or 1,1＇-bis-amines were prepared with high diastereoselectivity. Removal of the a-methylbenzyl group afforded the optically active primary mono- and bis-ferrocenylethylamines in high yields. The absolute configuration of （R,R）-3a and （S,S）-3b was determined by X-ray single crystal diffraction.展开更多
文摘Due to using （R）- or （S）-a-methylbenzylamine as a chiral auxiliary, and low-temperature regime for reduction of the intermediate ferrocenyl-mono- or 1,1＇-bis-ketimines, the corresponding secondary mono- or 1,1＇-bis-amines were prepared with high diastereoselectivity. Removal of the a-methylbenzyl group afforded the optically active primary mono- and bis-ferrocenylethylamines in high yields. The absolute configuration of （R,R）-3a and （S,S）-3b was determined by X-ray single crystal diffraction.
