The dynamic model of a novel electric power steering （EPS） system integrated with active front steering function （the novel EPS system） is built. The concepts and quantitative expressions of the steering road feel...The dynamic model of a novel electric power steering （EPS） system integrated with active front steering function （the novel EPS system） is built. The concepts and quantitative expressions of the steering road feel, steering sensibility, and steering operation stability are introduced. Based on quality engineering theory, the optimization algorithm is proposed by integrating the Monte Carlo descriptive sampling, elitist non-dominated sorting genetic algorithm （NSGA-II） and 6-sigma design method. With the steering road feel and the steering portability as optimization targets, the system parameters are optimized by the proposed optimization algorithm. The simulation results show that the system optimized based on quality engineering theory can improve the steering road feel, guarantee steering stability and steering portability and thus provide a theoretical basis for the design and optimization of the novel electric power steering system.展开更多
该文考察了黑格尔哲学体系中“疯狂”概念位置调整的内在逻辑。研究发现,从纽伦堡时期的手稿到1830年版《哲学科学百科全书》(the Encyclopedia of the Philosophical Sciences),“疯狂”概念经历了从理性部分的想象力环节到感觉灵魂阶...该文考察了黑格尔哲学体系中“疯狂”概念位置调整的内在逻辑。研究发现,从纽伦堡时期的手稿到1830年版《哲学科学百科全书》(the Encyclopedia of the Philosophical Sciences),“疯狂”概念经历了从理性部分的想象力环节到感觉灵魂阶段的变动。在纽伦堡时期,“疯狂”作为高位的“准统摄能力”,虽然符合想象力的语境,但造成了阶位反转和概念进展中断的体系张力。《哲学科学百科全书》通过将“疯狂”前移至感觉灵魂阶段,有效化解了原有的结构困难。然而,这一调整策略也产生了新的体系张力。该文通过文本比较揭示了黑格尔体系建构中“修复与代价”的基本模式,表明了其体系安排并非任意拼接,而是在不同结构压力间寻求平衡的产物。展开更多
Amid the recent global upsurge of studies on the philosophy of emotion, a reinterpretation of traditional Confucian philosophy, especially Mencius＇s ideas on the siduan （Four Original Sources） of morality, may shed...Amid the recent global upsurge of studies on the philosophy of emotion, a reinterpretation of traditional Confucian philosophy, especially Mencius＇s ideas on the siduan （Four Original Sources） of morality, may shed new light on the subject in comparative philosophy. This paper probes the structure of moral feeling and reason described by Mencius＇s from five perspectives： （1） In view of the relationship between feeling and reason, is it better to use the expression ＂siduan＂ or the expression ＂sixin （Four Heart-minds）＂？ （2） In view of dispositional feeling, what are the four original sources？ （3） In view of moral feeling, what are the structural order of the four sources and the corresponding procedure of reasoning of four heart-minds of Humanity？ （4） In view of positive feeling, how does moral feeling grow out of the goodness of human nature？ （5） What is the global value of Mencius＇s ideas on human moral feeling？ The author concludes that Mencius＇s thought on moral feeing has a global value and cross-cultural significance, and that Chinese wisdom is more than regional but universally applicable. The structure of moral feeling and reason that Mencius identified is in accordance with the principles ofzhiliang （grasping the two poles of the beginning and the end） and yongzhong （emloying the middle）. The principles ofzhiliang and yongzhong are true universal wisdoms of Confucianism, which should be rekindled today. From a practical point of view, ＂the Way begins from moral feelings,＂ and Confucius and Yah Hui＇s seeking the simple, virtuous life is an ideal model of emotional well-being.展开更多
In this paper, the performance of a column-type electric power steering （EPS） system and vehicle has been studied and a detailed mathematical model for the system has been established. Based on the mathematic model ...In this paper, the performance of a column-type electric power steering （EPS） system and vehicle has been studied and a detailed mathematical model for the system has been established. Based on the mathematic model of the optimization design for steering feel, the parameters of the EPS system and vehicle on steering performance have been investigated. Moreover, the effects of the parameters on system stability have been analyzed and compared by the method of absolute sensitivity and the results are given in the end.展开更多
Recently, the demand of services for architectural space is more increasing due to the diversification and complication of people＇s needs. In this research, it is assumed that the robot will support people＇s various...Recently, the demand of services for architectural space is more increasing due to the diversification and complication of people＇s needs. In this research, it is assumed that the robot will support people＇s various needs and people＇s lives in the near future. In this study, the authors investigated the relationship between a robot and a person in quasi space close to actual life space. The authors carried out an experiment to clarify the feelings of worriment due to a robot in the living room in the case of Japanese males. This research aims to establish architecture techniques for robots and humans living together. In this experiment, the robot approached a male sitting on a sofa in quasi space. At different distances between the robot and the male, the subject evaluated his feelings of worriment from ＂no worriment＂ to ＂worriment＂ in five steps from one to five. The robot used in this experiment is middle-sized （380 mm （L） × 380 mm （W） × 350 mm （H））. In this experiment, it is considered that the robot asks for help outside when an emergency occurs. In this experiment, the authors had three situations for the subject： watching television, reading a magazine and just sitting.展开更多
This paper not only introduce fuzzy mathematic method into the evaluation of fabrics’style and put forward a new comprehensive fuzzy method on the fabric’s evaluate,but also develop a set of software to set automati...This paper not only introduce fuzzy mathematic method into the evaluation of fabrics’style and put forward a new comprehensive fuzzy method on the fabric’s evaluate,but also develop a set of software to set automatic valuation of fabric’s style,“the intelligent system evaluation of fabric”.The system quoted the expert system principle.展开更多
Setting one’s mind at complete rest dur-ing Qigong requires a process which includesadjustment of the body,breathing andmind,with adjustment of mind as most im-portant.As adjustment of the mind may beregarded as the ...Setting one’s mind at complete rest dur-ing Qigong requires a process which includesadjustment of the body,breathing andmind,with adjustment of mind as most im-portant.As adjustment of the mind may beregarded as the thought process,we may saythat the thought process is the key to put-ring one’s mind at complete rest.展开更多
Background: “Children with severe motor and intellectual disabilities” refers to children with markedly limited activity due to severe overlapping of physical and intellectual disabilities. The physical and mental b...Background: “Children with severe motor and intellectual disabilities” refers to children with markedly limited activity due to severe overlapping of physical and intellectual disabilities. The physical and mental burden placed on families raising severely disabled children, particularly the primary caregivers, is great in home settings. For families to effectively utilize services and over-come child rearing problems, the families themselves need the “strength” to cooperate with others for the purpose of raising a severely disabled child. The ultimate goal of family support is to enable such families to achieve satisfaction and self-growth in child rearing. Methods: We used a questionnaire to survey 75 primary caregivers to empirically elucidate the empowerment and positive feelings towards child rearing of families raising children with severe motor and intellectual disabilities and the related factors. The t-test and Spearman’s rank correlation coefficient were used to examine the association with bivariates. A multiple regression analysis was conducted for empowerment and positive feelings. Results: Results revealed that life events, livelihood, awareness of social support and the child’s sleep problems were factors related to empowerment. Of these, awareness of social support from outside of the family was found to contribute the most to empowerment. Furthermore, improvement and maintenance of positive feelings towards child rearing reaffirmed the existence of empowerment in addition to reducing negative feelings towards child rearing and ensuring social support. Conclusions: Raising children with severe motor and intellectual disabilities requires specialist knowledge and skills. Support from professionals to empower the entire family is therefore important in order to strengthen positive feelings towards child rearing.展开更多
Mental disorders are a significant cause of disability and loss of workplace productivity. Many people with mental illness want to work. Occupational health in the world has to face up to psychosocial risks to protect...Mental disorders are a significant cause of disability and loss of workplace productivity. Many people with mental illness want to work. Occupational health in the world has to face up to psychosocial risks to protect the health of employees. My study aims are to improve negative feelings in work place and work functioning and to stimulate better coping mechanisms. Participants were collected from “Mental health daycare facility”, “Regional living assistance center” and “B-type employment assistance office” in Japan. I took interviews with 25 members. The content of the interviews was categorized about negative feelings in work place. A total of 33 small category negative feelings of mental disorder were extracted and were classified into 11 subcategories. These subcategories were then classified into two higher-level categories: inward-directed feelings and outward-directed feelings. Inward-directed feelings include “reserve or timidity,” “hesitation about being open about the illness,” “anxiety about being dismissed,” “regrets about resigning,” “sense of isolation,” “feelings of remorse,” and “suffering.” Outward-directed feelings include “failure in interpersonal relationships,” “distrust,” “frustrations,” “negative feelings toward those with mental disorder.” Employment has been linked to having better social networks, to enhanced quality of life and to overall wellbeing. We will have to defend them legally. The legal and moral obligations placed on the employer require that it provides a healthy, harassment-free work environment.展开更多
For centuries, the question of how a physical structure (the brain) generates the subjective feeling of consciousness has plagued neuroscientists, physiologists, psychologists, linguists, and philosophers. This has be...For centuries, the question of how a physical structure (the brain) generates the subjective feeling of consciousness has plagued neuroscientists, physiologists, psychologists, linguists, and philosophers. This has become known as the “hard problem of consciousness” and has been the subject of many publications. Although lots of answers have been proposed, none has been completely satisfactory. The focus of most of these studies has been on the neuronal structures and activities. Experiential consciousness emerges from neural processes, but it has not been explained with models that have been based solely on the electro-mechanical aspects of the processes. There must be some other dynamic features of neuronal activity to explain the emergence of experiential consciousness. I argue that a likely answer to the dilemma resides in the added dimension of the neurochemistry of the brain that has, so far, received little attention.展开更多
The aim of this study was to compare serum 17β-estradiol of menopausal women with/without Oral Dryness (OD) feeling, and evaluate the re-lationship between serum 17β-estradiol and severity of OD feeling. A case-cont...The aim of this study was to compare serum 17β-estradiol of menopausal women with/without Oral Dryness (OD) feeling, and evaluate the re-lationship between serum 17β-estradiol and severity of OD feeling. A case-control study was carried out on 70 selected menopausal women aged 40 - 77 years with or without OD feeling (35 as case, 35 as control) conducted at the Clinic of Oral Medicine, Tehran University of Medical Sciences. Xerostomia inventory (XI) score was used as an index of OD feeling severity. The serum 17β-estradiol concentration was measured by an enzyme immunoassay kit (ELISA). Statistical analysis of Student’s t-test and Spearman correlation coefficient was used. The mean serum concentration of 17β-estradiol was significantly lower in case than control. There was a significant negative correlation between XI score and concentration of 17β-estradiol in menopausal women (r = –0.311, P = 0.004). It seems that there is a negatively slight correlation between OD feeling severity and serum 17β-estradiol in menopausal women.展开更多
[ Objective] The study aimed to forecast human body feeling temperature. [ Method] Using air temperature data outside shutter boxes of cement and asphalt underlying surface at 1.5 m and conventional observation data f...[ Objective] The study aimed to forecast human body feeling temperature. [ Method] Using air temperature data outside shutter boxes of cement and asphalt underlying surface at 1.5 m and conventional observation data from 2008 to 2010 as well as T639 and Japan numerical forecast product, the characteristics of the minimum temperature in winter half year and the maximum temperature in summer half year in Changzhou were analyzed, and the prediction equation of the maximum temperature from May to September as well as year-round comfort prediction index were es- tablished. Moreover, the announcement platform of human body feeling temperature was developed to forecast it. [ Result] There remained a tiny discrepancy in the winter minimum temperature between inside and outside shutter box, and clays with the minimum temperature difference lower than 2 ℃ accounted for 94.3% of total days. However, the summer maximum temperature difference between inside and outside shutter box was larger, and days with the maximum temperature difference higher than 2 ℃ accounted for 82.0%, while the maximum difference was 5.5 ℃. The prediction accuracy of the inside maximum temperature was 78%. Wind was considered as the primary factor based on the effective temperature, and comfort index forecast and service were determined based on human feelings, dress, meteorological care and so forth. Both human body feel- ing temperature and comfort index forecast were released in the temperature forecast service. [ Condusion] The prediction of human body feeling temperature could provide scientific references for people＇s dress and traveling in daily life.展开更多
BACKGROUND While the impact of depression on cognition is well-documented,the relationship between feelings and cognition has received limited attention.AIM To explore the potential association between feelings and co...BACKGROUND While the impact of depression on cognition is well-documented,the relationship between feelings and cognition has received limited attention.AIM To explore the potential association between feelings and cognition with a twosample Mendelian randomization(MR)analysis.METHODS Our analysis utilized genome-wide association data on various feelings(fed-up feelings,n=453071;worrier/anxious feelings,n=450765;guilty feelings,n=45-0704;nervous feelings,n=450700;sensitivity/hurt feelings,n=449419;miserableness,n=454982;loneliness/isolation,n=455364;happiness,n=152348)in the European population and their impact on cognitive functions(intelligence,n=269867).Conducting a univariable MR(UVMR)analysis to assess the relationship between feelings and cognition.In this analysis,we applied the inverse variance weighting(IVW),weighted median,and MR Egger methods.Additionally,we performed sensitivity analysis(leave-one-out analysis),assessed heterogeneity(using MR-PRESSO and Cochran’s Q test),and conducted multiple validity test(employing MR-Egger regression).Subsequently,a multivariable MR(MVMR)analysis was employed to examine the impact of feelings on cognition.IVW served as the primary method in the multivariable analysis,complemented by median-based and MR-Egger methods.RESULTS In this study,UVMR indicated that sensitivity/hurt feelings may have a negative causal effect on cognition(OR=0.63,95%CI:0.43-0.92,P=0.017).After adjustment of other feelings using MVMR,a direct adverse causal effect on cognition was observed(OR_(MVMR)=0.39,95%CI:0.17-0.90,P_(MVMR)=0.027).While a potential increased risk of cognitive decline was observed for fed-up feelings in the UVMR analysis(ORUVMR=0.64,95%CI:0.42-0.97,PUVMR=0.037),this effect disappeared after adjusting for other feelings(OR_(MVMR)=1.42,95%CI:0.43-4.74,P_(MVMR)=0.569).These findings were generally consistent across MV-IVW,median-based,and MR-Egger analyses.MR-Egger regression revealed pleiotropy in the impact of worrier/anxious feelings on cognition,presenting a challenge in identifying the effect.Notably,this study did not demonstrate any significant impact of guilty feelings,nervous feelings,miserableness,or loneliness/isolation on cognition.Due to a limited number of instrumental variables for happiness,this study was unable to analyze the relationship between happiness and cognition.CONCLUSION This MR study finds that sensitivity/hurt feelings are associated with cognitive decline,while the link between worrier/anxious feelings and cognition remains inconclusive.Insufficient evidence supports direct associations between happiness,guilty feelings,nervous feelings,miserableness,loneliness/isolation,and cognition.展开更多
Henry Mackenzie＇ s The Man of Feeling （1771 ）, widely read m its time, has been generally regarded as an exemplar of sentimental fiction. As a typical man of the world, Mackenzie made arduous efforts to distance hi...Henry Mackenzie＇ s The Man of Feeling （1771 ）, widely read m its time, has been generally regarded as an exemplar of sentimental fiction. As a typical man of the world, Mackenzie made arduous efforts to distance himself from Harley, the simple and naive sentimental hero he created in his novel. The novel described how the innocence and tenderness of Harley were thwarted by the evil world and how Harley responded with sighs and tears. The same response was asked of the reader. Hence, readings of sentimental novels became tear-demanding exhibitions of pathos, while the unkindness and perverseness of the world were minimized and even concealed.展开更多
基金Projects(51005115,51205191)supported by the National Natural Science Foundation of ChinaProject(QC201101)supported by the Visiting Scholar Foundation of the Automobile Engineering Key Laboratory of Jiangsu Province,China+1 种基金Project(SKLMT-KFKT-201105)supported by the Visiting Scholar Foundation of the State Key Laboratory of Mechanical Transmission in Chongqing University,ChinaProjects(NS2013015,NS2012086)supported by the Funds from the Postgraduate Creative Base in Nanjing University of Areonautics and Astronautics,and NUAA Research Funding,China
文摘The dynamic model of a novel electric power steering （EPS） system integrated with active front steering function （the novel EPS system） is built. The concepts and quantitative expressions of the steering road feel, steering sensibility, and steering operation stability are introduced. Based on quality engineering theory, the optimization algorithm is proposed by integrating the Monte Carlo descriptive sampling, elitist non-dominated sorting genetic algorithm （NSGA-II） and 6-sigma design method. With the steering road feel and the steering portability as optimization targets, the system parameters are optimized by the proposed optimization algorithm. The simulation results show that the system optimized based on quality engineering theory can improve the steering road feel, guarantee steering stability and steering portability and thus provide a theoretical basis for the design and optimization of the novel electric power steering system.
文摘该文考察了黑格尔哲学体系中“疯狂”概念位置调整的内在逻辑。研究发现,从纽伦堡时期的手稿到1830年版《哲学科学百科全书》(the Encyclopedia of the Philosophical Sciences),“疯狂”概念经历了从理性部分的想象力环节到感觉灵魂阶段的变动。在纽伦堡时期,“疯狂”作为高位的“准统摄能力”,虽然符合想象力的语境,但造成了阶位反转和概念进展中断的体系张力。《哲学科学百科全书》通过将“疯狂”前移至感觉灵魂阶段,有效化解了原有的结构困难。然而,这一调整策略也产生了新的体系张力。该文通过文本比较揭示了黑格尔体系建构中“修复与代价”的基本模式,表明了其体系安排并非任意拼接,而是在不同结构压力间寻求平衡的产物。
文摘Amid the recent global upsurge of studies on the philosophy of emotion, a reinterpretation of traditional Confucian philosophy, especially Mencius＇s ideas on the siduan （Four Original Sources） of morality, may shed new light on the subject in comparative philosophy. This paper probes the structure of moral feeling and reason described by Mencius＇s from five perspectives： （1） In view of the relationship between feeling and reason, is it better to use the expression ＂siduan＂ or the expression ＂sixin （Four Heart-minds）＂？ （2） In view of dispositional feeling, what are the four original sources？ （3） In view of moral feeling, what are the structural order of the four sources and the corresponding procedure of reasoning of four heart-minds of Humanity？ （4） In view of positive feeling, how does moral feeling grow out of the goodness of human nature？ （5） What is the global value of Mencius＇s ideas on human moral feeling？ The author concludes that Mencius＇s thought on moral feeing has a global value and cross-cultural significance, and that Chinese wisdom is more than regional but universally applicable. The structure of moral feeling and reason that Mencius identified is in accordance with the principles ofzhiliang （grasping the two poles of the beginning and the end） and yongzhong （emloying the middle）. The principles ofzhiliang and yongzhong are true universal wisdoms of Confucianism, which should be rekindled today. From a practical point of view, ＂the Way begins from moral feelings,＂ and Confucius and Yah Hui＇s seeking the simple, virtuous life is an ideal model of emotional well-being.
基金Project supported by the National Natural Science Foundation of China (Grant No.60674067)the Scientific and Techno-logical Foundation of Hubei Province (Grant No.2006AA101B13)
文摘In this paper, the performance of a column-type electric power steering （EPS） system and vehicle has been studied and a detailed mathematical model for the system has been established. Based on the mathematic model of the optimization design for steering feel, the parameters of the EPS system and vehicle on steering performance have been investigated. Moreover, the effects of the parameters on system stability have been analyzed and compared by the method of absolute sensitivity and the results are given in the end.
文摘Recently, the demand of services for architectural space is more increasing due to the diversification and complication of people＇s needs. In this research, it is assumed that the robot will support people＇s various needs and people＇s lives in the near future. In this study, the authors investigated the relationship between a robot and a person in quasi space close to actual life space. The authors carried out an experiment to clarify the feelings of worriment due to a robot in the living room in the case of Japanese males. This research aims to establish architecture techniques for robots and humans living together. In this experiment, the robot approached a male sitting on a sofa in quasi space. At different distances between the robot and the male, the subject evaluated his feelings of worriment from ＂no worriment＂ to ＂worriment＂ in five steps from one to five. The robot used in this experiment is middle-sized （380 mm （L） × 380 mm （W） × 350 mm （H））. In this experiment, it is considered that the robot asks for help outside when an emergency occurs. In this experiment, the authors had three situations for the subject： watching television, reading a magazine and just sitting.
文摘This paper not only introduce fuzzy mathematic method into the evaluation of fabrics’style and put forward a new comprehensive fuzzy method on the fabric’s evaluate,but also develop a set of software to set automatic valuation of fabric’s style,“the intelligent system evaluation of fabric”.The system quoted the expert system principle.
文摘Setting one’s mind at complete rest dur-ing Qigong requires a process which includesadjustment of the body,breathing andmind,with adjustment of mind as most im-portant.As adjustment of the mind may beregarded as the thought process,we may saythat the thought process is the key to put-ring one’s mind at complete rest.
文摘Background: “Children with severe motor and intellectual disabilities” refers to children with markedly limited activity due to severe overlapping of physical and intellectual disabilities. The physical and mental burden placed on families raising severely disabled children, particularly the primary caregivers, is great in home settings. For families to effectively utilize services and over-come child rearing problems, the families themselves need the “strength” to cooperate with others for the purpose of raising a severely disabled child. The ultimate goal of family support is to enable such families to achieve satisfaction and self-growth in child rearing. Methods: We used a questionnaire to survey 75 primary caregivers to empirically elucidate the empowerment and positive feelings towards child rearing of families raising children with severe motor and intellectual disabilities and the related factors. The t-test and Spearman’s rank correlation coefficient were used to examine the association with bivariates. A multiple regression analysis was conducted for empowerment and positive feelings. Results: Results revealed that life events, livelihood, awareness of social support and the child’s sleep problems were factors related to empowerment. Of these, awareness of social support from outside of the family was found to contribute the most to empowerment. Furthermore, improvement and maintenance of positive feelings towards child rearing reaffirmed the existence of empowerment in addition to reducing negative feelings towards child rearing and ensuring social support. Conclusions: Raising children with severe motor and intellectual disabilities requires specialist knowledge and skills. Support from professionals to empower the entire family is therefore important in order to strengthen positive feelings towards child rearing.
文摘Mental disorders are a significant cause of disability and loss of workplace productivity. Many people with mental illness want to work. Occupational health in the world has to face up to psychosocial risks to protect the health of employees. My study aims are to improve negative feelings in work place and work functioning and to stimulate better coping mechanisms. Participants were collected from “Mental health daycare facility”, “Regional living assistance center” and “B-type employment assistance office” in Japan. I took interviews with 25 members. The content of the interviews was categorized about negative feelings in work place. A total of 33 small category negative feelings of mental disorder were extracted and were classified into 11 subcategories. These subcategories were then classified into two higher-level categories: inward-directed feelings and outward-directed feelings. Inward-directed feelings include “reserve or timidity,” “hesitation about being open about the illness,” “anxiety about being dismissed,” “regrets about resigning,” “sense of isolation,” “feelings of remorse,” and “suffering.” Outward-directed feelings include “failure in interpersonal relationships,” “distrust,” “frustrations,” “negative feelings toward those with mental disorder.” Employment has been linked to having better social networks, to enhanced quality of life and to overall wellbeing. We will have to defend them legally. The legal and moral obligations placed on the employer require that it provides a healthy, harassment-free work environment.
文摘For centuries, the question of how a physical structure (the brain) generates the subjective feeling of consciousness has plagued neuroscientists, physiologists, psychologists, linguists, and philosophers. This has become known as the “hard problem of consciousness” and has been the subject of many publications. Although lots of answers have been proposed, none has been completely satisfactory. The focus of most of these studies has been on the neuronal structures and activities. Experiential consciousness emerges from neural processes, but it has not been explained with models that have been based solely on the electro-mechanical aspects of the processes. There must be some other dynamic features of neuronal activity to explain the emergence of experiential consciousness. I argue that a likely answer to the dilemma resides in the added dimension of the neurochemistry of the brain that has, so far, received little attention.
文摘The aim of this study was to compare serum 17β-estradiol of menopausal women with/without Oral Dryness (OD) feeling, and evaluate the re-lationship between serum 17β-estradiol and severity of OD feeling. A case-control study was carried out on 70 selected menopausal women aged 40 - 77 years with or without OD feeling (35 as case, 35 as control) conducted at the Clinic of Oral Medicine, Tehran University of Medical Sciences. Xerostomia inventory (XI) score was used as an index of OD feeling severity. The serum 17β-estradiol concentration was measured by an enzyme immunoassay kit (ELISA). Statistical analysis of Student’s t-test and Spearman correlation coefficient was used. The mean serum concentration of 17β-estradiol was significantly lower in case than control. There was a significant negative correlation between XI score and concentration of 17β-estradiol in menopausal women (r = –0.311, P = 0.004). It seems that there is a negatively slight correlation between OD feeling severity and serum 17β-estradiol in menopausal women.
基金Supported by the Fund of Jiangsu Meteorological Bureau,China(200609)
文摘[ Objective] The study aimed to forecast human body feeling temperature. [ Method] Using air temperature data outside shutter boxes of cement and asphalt underlying surface at 1.5 m and conventional observation data from 2008 to 2010 as well as T639 and Japan numerical forecast product, the characteristics of the minimum temperature in winter half year and the maximum temperature in summer half year in Changzhou were analyzed, and the prediction equation of the maximum temperature from May to September as well as year-round comfort prediction index were es- tablished. Moreover, the announcement platform of human body feeling temperature was developed to forecast it. [ Result] There remained a tiny discrepancy in the winter minimum temperature between inside and outside shutter box, and clays with the minimum temperature difference lower than 2 ℃ accounted for 94.3% of total days. However, the summer maximum temperature difference between inside and outside shutter box was larger, and days with the maximum temperature difference higher than 2 ℃ accounted for 82.0%, while the maximum difference was 5.5 ℃. The prediction accuracy of the inside maximum temperature was 78%. Wind was considered as the primary factor based on the effective temperature, and comfort index forecast and service were determined based on human feelings, dress, meteorological care and so forth. Both human body feel- ing temperature and comfort index forecast were released in the temperature forecast service. [ Condusion] The prediction of human body feeling temperature could provide scientific references for people＇s dress and traveling in daily life.
文摘BACKGROUND While the impact of depression on cognition is well-documented,the relationship between feelings and cognition has received limited attention.AIM To explore the potential association between feelings and cognition with a twosample Mendelian randomization(MR)analysis.METHODS Our analysis utilized genome-wide association data on various feelings(fed-up feelings,n=453071;worrier/anxious feelings,n=450765;guilty feelings,n=45-0704;nervous feelings,n=450700;sensitivity/hurt feelings,n=449419;miserableness,n=454982;loneliness/isolation,n=455364;happiness,n=152348)in the European population and their impact on cognitive functions(intelligence,n=269867).Conducting a univariable MR(UVMR)analysis to assess the relationship between feelings and cognition.In this analysis,we applied the inverse variance weighting(IVW),weighted median,and MR Egger methods.Additionally,we performed sensitivity analysis(leave-one-out analysis),assessed heterogeneity(using MR-PRESSO and Cochran’s Q test),and conducted multiple validity test(employing MR-Egger regression).Subsequently,a multivariable MR(MVMR)analysis was employed to examine the impact of feelings on cognition.IVW served as the primary method in the multivariable analysis,complemented by median-based and MR-Egger methods.RESULTS In this study,UVMR indicated that sensitivity/hurt feelings may have a negative causal effect on cognition(OR=0.63,95%CI:0.43-0.92,P=0.017).After adjustment of other feelings using MVMR,a direct adverse causal effect on cognition was observed(OR_(MVMR)=0.39,95%CI:0.17-0.90,P_(MVMR)=0.027).While a potential increased risk of cognitive decline was observed for fed-up feelings in the UVMR analysis(ORUVMR=0.64,95%CI:0.42-0.97,PUVMR=0.037),this effect disappeared after adjusting for other feelings(OR_(MVMR)=1.42,95%CI:0.43-4.74,P_(MVMR)=0.569).These findings were generally consistent across MV-IVW,median-based,and MR-Egger analyses.MR-Egger regression revealed pleiotropy in the impact of worrier/anxious feelings on cognition,presenting a challenge in identifying the effect.Notably,this study did not demonstrate any significant impact of guilty feelings,nervous feelings,miserableness,or loneliness/isolation on cognition.Due to a limited number of instrumental variables for happiness,this study was unable to analyze the relationship between happiness and cognition.CONCLUSION This MR study finds that sensitivity/hurt feelings are associated with cognitive decline,while the link between worrier/anxious feelings and cognition remains inconclusive.Insufficient evidence supports direct associations between happiness,guilty feelings,nervous feelings,miserableness,loneliness/isolation,and cognition.
基金This paper is supported by Science Foundation of BLCU （supported by ＂the Fundamental Research Funds for the Central Universities＂） （No. 12YBG022）.
文摘Henry Mackenzie＇ s The Man of Feeling （1771 ）, widely read m its time, has been generally regarded as an exemplar of sentimental fiction. As a typical man of the world, Mackenzie made arduous efforts to distance himself from Harley, the simple and naive sentimental hero he created in his novel. The novel described how the innocence and tenderness of Harley were thwarted by the evil world and how Harley responded with sighs and tears. The same response was asked of the reader. Hence, readings of sentimental novels became tear-demanding exhibitions of pathos, while the unkindness and perverseness of the world were minimized and even concealed.
