The phenyl and methyl phenyl free radicals,formed in the oxidation-hydrolysis process of N’-acyl-N-phenylhydrazine, have been studied by ESR spectrometry.It was found that the free radical is the chief cause which pr...The phenyl and methyl phenyl free radicals,formed in the oxidation-hydrolysis process of N’-acyl-N-phenylhydrazine, have been studied by ESR spectrometry.It was found that the free radical is the chief cause which produces the feed-back inhibition effect in the hydrazine-promoted infectious development of silver halide.展开更多
The variable-structure multiple-model（VSMM）approach,one of the multiple-model（MM）methods,is a popular and effective approach in handling problems with mode uncertainties.The model sequence set adaptation（MSA）is ...The variable-structure multiple-model（VSMM）approach,one of the multiple-model（MM）methods,is a popular and effective approach in handling problems with mode uncertainties.The model sequence set adaptation（MSA）is the key to design a better VSMM.However,MSA methods in the literature have big room to improve both theoretically and practically.To this end,we propose a feedback structure based entropy approach that could fnd the model sequence sets with the smallest size under certain conditions.The fltered data are fed back in real time and can be used by the minimum entropy（ME）based VSMM algorithms,i.e.,MEVSMM.Firstly,the full Markov chains are used to achieve optimal solutions.Secondly,the myopic method together with particle flter（PF）and the challenge match algorithm are also used to achieve sub-optimal solutions,a trade-off between practicability and optimality.The numerical results show that the proposed algorithm provides not only refned model sets but also a good robustness margin and very high accuracy.展开更多
To solve the problem of water seepage of vertical feeding borehole for solid materials,we established the fluid-solid coupling dynamic model of groundwater flowing in rock mass adjacent to the vertical feeding borehol...To solve the problem of water seepage of vertical feeding borehole for solid materials,we established the fluid-solid coupling dynamic model of groundwater flowing in rock mass adjacent to the vertical feeding borehole.Combining with the engineering geological conditions,we built a numeral model to study the influence rule of the aquifer hydraulic pressure and seepage location of feeding borehole on the amount of seepage with fnite element numerical method.The results show that the nonlinear relationship is presented among the amount of seepage,the seepage location and aquifer hydraulic pressure.The higher the aquifer hydraulic pressure is,the closer the distance between seepage location and aquifer is,and the faster the harmful levels of aquifer will grow.In practice,we calculated the allowable seepage of feeding borehole by the optimum moisture content and natural moisture content of backflling materials,and then determined the protection zone of feeding borehole,so the moisture content of backflling materials can be controlled within the scope of optimum moisture content.展开更多
A modified coupled map car-following model is proposed, in which two successive vehicle headways in front of the considering vehicle is incorporated into the optimal velocity function. The steady state under certain c...A modified coupled map car-following model is proposed, in which two successive vehicle headways in front of the considering vehicle is incorporated into the optimal velocity function. The steady state under certain conditions is obtained. An error system around the steady state is studied further. Moreover, the condition for the state having no traffic jam is derived. A new control scheme is presented to suppress the traffic jam in the modified coupled map car-following model under the open boundary. A control signal including the velocity differences between the following and the considering vehicles, and between the preceding and the considering vehicles is used. The condition under which the traffic jam can be well suppressed is analysed. The results are compared with that presented by t^onishi et al. （the KKH model）. The simulation results show that the temporal behaviour obtained in our model is better than that in the KKH model. The simulation results are in good agreement with the theoretical analysis.展开更多
As the performance of an air-cooled condenser is apt to be affected by the fluctuating ambient condition, some difficulties are brought to the use of a steam feeding water pump in an air-cooled unit. This paper introd...As the performance of an air-cooled condenser is apt to be affected by the fluctuating ambient condition, some difficulties are brought to the use of a steam feeding water pump in an air-cooled unit. This paper introduces a new design of for steam feeding the water pump of an air-cooled unit using the back-pressure steam turbine as the prime motor. Using variable condition analysis on a 600 MW direct air-cooled unit, and with consideration of the effect on the ambient conditions, the feasibility, economy, and adaptability of the design are verified.展开更多
Reciprocal oscillographic chronopotentiogram is such a curve that can converts incisions on "(dE/dt)-E" oscillogram into peaks on "(dt/dE)-E" curve. In order to increase the sensitivity, a new tech...Reciprocal oscillographic chronopotentiogram is such a curve that can converts incisions on "(dE/dt)-E" oscillogram into peaks on "(dt/dE)-E" curve. In order to increase the sensitivity, a new technique called feeding back current was added in new circuit of obtaining reciprocal oscillgraphic chronopotentiogram. It can make capacity current be subtracted easily. Using this method, we carry out studying on principle and titration of drug.展开更多
This paper studies the problem of robust controller design for linear perturbed continuous stochasticsystems with variance constraints via output feedback. The goal is to design static output feedback controllers such...This paper studies the problem of robust controller design for linear perturbed continuous stochasticsystems with variance constraints via output feedback. The goal is to design static output feedback controllers suchthat the uncertain system has the desil'ed stability margin and the steady-state variance constraints. The existenceconditions for the desired controllers are discussed, and the analytical expression of these controllers is alsocharacterized. A numerical example is provided to demonstrate the directness and effectiveness of the proposedmethod.展开更多
In the face of constantly changing environments,the central nervous system(CNS)rapidly and accurately calculates the body's needs,regulates feeding behavior,and maintains energy homeostasis.The arcuate nucleus of ...In the face of constantly changing environments,the central nervous system(CNS)rapidly and accurately calculates the body's needs,regulates feeding behavior,and maintains energy homeostasis.The arcuate nucleus of the hypothalamus(ARC)plays a key role in this process,serv-ing as a critical brain region for detecting nutrition-related hormones and regulating appetite and energy homeostasis.Agouti-related protein(AgRP)/neuropeptide Y(NPY)neu-rons in the ARC are core elements that interact with other brain regions through a complex appetite-regulating network to comprehensively control energy homeostasis.In this review,we explore the discovery and research progress of AgRP neurons in regulating feeding and energy metabolism.In addition,recent advances in terms of feeding behavior and energy homeostasis,along with the redundant neural mecha-nisms involved in energy metabolism,are discussed.Finally,the challenges and opportunities in the field of neural regula-tion of feeding and energy metabolism are briefly discussed.展开更多
Background Post-weaning diarrhea(PWD)in piglets,often caused by F4^(+)enterotoxigenic Escherichia coli(ETEC),poses significant challenges in pig production.Traditional solutions like antibiotics and zinc oxide face in...Background Post-weaning diarrhea(PWD)in piglets,often caused by F4^(+)enterotoxigenic Escherichia coli(ETEC),poses significant challenges in pig production.Traditional solutions like antibiotics and zinc oxide face increasing restrictions due to growing concerns over antibiotic resistance and environmental sustainability.This study investigates the application of bivalent heavy chain variable domain(V_(H)H)constructs(BL1.2 and BL2.2)targeting ETEC virulence factors,administered in feed to mitigate ETEC-induced PWD in weaned piglets.Results The supplementation of BL1.2 and BL2.2 in both mash and pelleted feed significantly reduced the diarrhea incidence and fecal shedding of F4^(+)ETEC in challenged piglets.Pelleted feed containing V_(H)H constructs helped to preserve gut barrier integrity by maintaining levels of the tight junction protein occludin in the small intestine.Additionally,the constructs maintained blood granulocyte counts at a similar level to the non-challenged control group,including neutrophils,and ameliorated the acute phase protein response after challenge.Notably,even at low feed intake immediately after weaning,V_(H)H constructs helped maintain piglet health by mitigating ETEC-induced inflammation and the resulting diarrhea.Conclusions Our findings demonstrated that using V_(H)H constructs as feed additives could serve as an effective strategy to help manage ETEC-associated PWD,by reducing F4^(+)ETEC gut colonization and supporting gut barrier function of weaned piglets.The high stability of these V_(H)H constructs supports their incorporation into industrial feed manufacturing processes,offering a more sustainable preventive strategy compared to traditional antimicrobial interventions,which could contribute to sustainable farming practices.展开更多
"Adventures with Dad"(August 2021)After reading the article"Adventures with Dad,"I also have a story to share.Thirty years ago,Iwas a high school student staying home for the Chinese New Year[holid..."Adventures with Dad"(August 2021)After reading the article"Adventures with Dad,"I also have a story to share.Thirty years ago,Iwas a high school student staying home for the Chinese New Year[holiday].展开更多
This minireview synthesizes literature on the use of feeding jejunostomy tubes(FJTs)in the postoperative management of gastroesophageal cancer patients.Gastrectomy and esophagectomy remain the primary curative treatme...This minireview synthesizes literature on the use of feeding jejunostomy tubes(FJTs)in the postoperative management of gastroesophageal cancer patients.Gastrectomy and esophagectomy remain the primary curative treatments for gastric and esophageal cancers,respectively,but are frequently accompanied by significant postoperative malnutrition,which adversely impacts surgical and oncological outcomes as well as patients’quality of life.To address this,the European Society for Clinical Nutrition and Surgery and the National Comprehensive Cancer Network recommend early enteral feeding through FJT placement following major surgery.While previous studies have demonstrated that FJT is an effective and reliable route for nutritional support,its placement is invasive and carries associated risks.Consequently,many clinicians opt for less invasive alternatives such as total parenteral nutrition or nasogastric tube feeding,although these approaches yield variable results.This review explores the benefits and potential complications of FJT placement,identifies variability in clinical adoption and the absence of standardized protocols,and highlights areas for future research to optimize patient care in this challenging context.展开更多
Microplastic(MP)pollution has spread from the mainland to the ocean.However,Haizhou Bay,which is one of the important land-ocean transition zones,has been reported relatively little about the enrichment of MPs.To prov...Microplastic(MP)pollution has spread from the mainland to the ocean.However,Haizhou Bay,which is one of the important land-ocean transition zones,has been reported relatively little about the enrichment of MPs.To provide fundamental data for MP pollution in Haizhou Bay,we studied the occurrence of microplastics in the intestines of 8 species of fish with different habits and feeding modes.The fish intestines were digested with a 10%KOH solution,and MPs are separated with a glass fiber filter.Then,the size,shape,color,and composition of the MPs were analyzed using a stereomicroscope and Fourier transform infrared spectrometer.The results showed the abundance of MP intake ranged from 0.02 items g^(-1) to 0.16 items g^(-1) and the detection rate of MPs ranged from 53.33% to 80% across different fish species.The MP intake in benthic fish and omnivorous fish was significantly higher than that of pelagic fish and predatory fish.Smaller MPs(<0.25 mm)were the dominant types and accounted for 62.50% of the total.The fiber was the prevailing shape of MPs,and the black MPs were the most common,followed by red and yellow ones.Polyethylene terephthalate(PET),polyamide(PA),and polystyrene(PS)were the main components of MPs,accounting for 34.9%,29.9%,and 16.4%,respectively.According to the composition analysis of MPs,the main sources of MPs in fish of Haizhou Bay were attributed to marine aquaculture and port construction.The results are helpful for our better understanding of the status of MP pollution in this area,and further aid in the development of the pointed measures to mitigate and prevent the MP pollution in this ecologically important area.展开更多
Feed efficiency(FE)is a crucial economic trait that significantly impacts profitability in intensive sheep production,and can be evaluated by the residual feed intake(RFI)and feed conversion ratio(FCR).However,the und...Feed efficiency(FE)is a crucial economic trait that significantly impacts profitability in intensive sheep production,and can be evaluated by the residual feed intake(RFI)and feed conversion ratio(FCR).However,the underlying genetic mechanisms that underlie FE-related traits in sheep are not fully understood.Herein,we measured the FE-related traits of 1,280 Hu sheep and conducted the phenotype statistics and correlation analysis,the result showcase that there was a large variation for FE-related traits,and RFI was significant positive correlation with average daily feed intake(ADFI)and FCR.Moreover,a genome-wide association study(GWAS)was conducted using whole-genome resequencing data to investigate the genetic associations of ADFI,FCR and RFI.For ADFI and FCR traits,2 and one single nucleotide polymorphisms(SNPs)exceeded the genome-wide significance threshold,whereas ten and 5 SNPs exceeded the suggestive significance threshold.For RFI traits,only 4 SNPs exceeded the suggestive significance threshold.Finally,a total of 8 genes(LOC101121953,LOC101110202,CTNNA3,IZUMO3,PPM1E,YIPF7,ZSCAN12and LOC105603808)were identified as potential candidate genes for FE-related traits.Simultaneously,we further analyzed the effects of 2 candidate SNPs associated with RFI on growth and FE traits in enlarged experimental population,the results demonstrated that these 2 SNPs was not significantly associated with growth traits(P>0.05),but significantly related to RFI traits(P<0.05).These findings will provide valuable reference data and key genetic variants that can be used to effectively select feed-efficient individual in sheep breeding programs.展开更多
The efficiency and mechanism of hydrous iron oxide(HFO)and HFO/calcite mixture to inactivate the phosphorus in the overlying water(OW)/sediment system under the feed adding condition were explored,and the effect of HF...The efficiency and mechanism of hydrous iron oxide(HFO)and HFO/calcite mixture to inactivate the phosphorus in the overlying water(OW)/sediment system under the feed adding condition were explored,and the effect of HFO and HFO/calcite mixture addition on the diversity,composition and function of bacterial communities in the sediment was examined.HFO and HFO/calcite mixture direct addition can effectively lower the concentration of soluble reactive phosphorus(RSP)and diffusion gradient in thin film-unstable phosphorus(PD GT)in OW and inactivate the P DGTin the upper sediment.The elimination efficiencies of RSP by the direct HFO and HFO/calcite mixture addition were 48.9%-97.0%and 42.4%-95.4%,respectively.The alteration in the addition mode from the one-time to multiple direct addition was beneficial to the immobilization of RSP and PD GTin OW and P DGTin the upper sediment by HFO and HFO/calcite mixture under the feed input condition in the long run.Permeable fabric wrapping reduced the inactivation efficiency of RSP in OW by HFO and HFO/calcite mixture,but it made the recycling of these materials possible.Most of P immobilized by HFO and HFO/calcite mixture was relatively or very stable.After the HFO and HFO/calcite mixture addition,the composition of bacterial communities in the surface sediment changed.However,the bacterial communities in the amended sediments still can perform good ecological function.Our findings suggest that HFO and HFO/calcite mixture are promising phosphorus-immobilization materials for the inactivation of RSP and PD GTin OW and PD GTin the upper sediment under the feed inputting condition.展开更多
The widespread ban on in-feed antibiotics in many regions has driven the search for natural alternatives to maintain health and production efficiency in swine and poultry.Phytogenic feed additives(PFAs)derived from he...The widespread ban on in-feed antibiotics in many regions has driven the search for natural alternatives to maintain health and production efficiency in swine and poultry.Phytogenic feed additives(PFAs)derived from herbs and plant extracts have emerged as promising candidates owing to their antioxidant,anti-inflammatory,and antimicrobial properties.Among these,silymarin—a flavonolignan complex extracted from milk thistle(Silybum marianum)—has attracted particular attention due to its hepatoprotective and growth-promoting activities.This review summarizes the chemical characteristics and mechanisms of action of silymarin/silybin.Also,evidence from both experimental and field studies shows that silymarin improves growth performance,nutrient digestibility,gut health,and reproductive outcomes.Advances in formulation technologies,such as micellization,have been addressed for improved bioavailability of silymarin.Despite these promising results,further long-term field studies and economic evaluations are needed to fully integrate silymarin into commercial animal production systems.展开更多
Background This study was carried out to investigate the individual and combined contamination of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON),and zearalenone(ZEN)in feeds in China between 2021 and 2024.A total of 23,...Background This study was carried out to investigate the individual and combined contamination of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON),and zearalenone(ZEN)in feeds in China between 2021 and 2024.A total of 23,003 feed samples,including 17,489 feedstuff samples and 5,514 complete feed samples,were collected from different provinces of China for mycotoxin analysis.Results The analyzed mycotoxins displayed considerably high contamination in the feed samples,with the individual contamination of AFB_(1),DON,and ZEN were 20.0%–100%,33.3%–100%,and 85.0%–100%,respectively.The average concentrations of AFB_(1),DON,and ZEN were 1.2–728.7μg/kg,106–8,634.8μg/kg,and 18.1–3,341.6μg/kg,respectively.Notably,the rates over China’s safety standards for AFB_(1),DON,and ZEN in raw ingredients were 9.7%,2.7%,and 15.7%,respectively.Meanwhile,3.5%,1.1%,and 8.7%of analyzed complete feeds exceeded China’s safety standards for AFB_(1),DON,and ZEN,respectively.Moreover,the co-contamination rates of AFB_(1),DON,and ZEN in more than 70%of raw ingredients and 87.5%of complete feed products were 60.0%–100%and 61.5%–100%,respectively.Conclusion This study reveals that the feeds in China have commonly been contaminated with AFB_(1),DON,and ZEN alone and their combination during the past four years.These findings highlight the significance of monitoring mycotoxin contaminant levels in domestic animal feed and the importance of carrying out feed administration and remediation strategies for mycotoxin control.展开更多
文摘The phenyl and methyl phenyl free radicals,formed in the oxidation-hydrolysis process of N’-acyl-N-phenylhydrazine, have been studied by ESR spectrometry.It was found that the free radical is the chief cause which produces the feed-back inhibition effect in the hydrazine-promoted infectious development of silver halide.
基金supported in part by National Basic Research Program of China(No.2012CB821200)in part by the National Natural Science Foundation of China(No.61174024)
文摘The variable-structure multiple-model（VSMM）approach,one of the multiple-model（MM）methods,is a popular and effective approach in handling problems with mode uncertainties.The model sequence set adaptation（MSA）is the key to design a better VSMM.However,MSA methods in the literature have big room to improve both theoretically and practically.To this end,we propose a feedback structure based entropy approach that could fnd the model sequence sets with the smallest size under certain conditions.The fltered data are fed back in real time and can be used by the minimum entropy（ME）based VSMM algorithms,i.e.,MEVSMM.Firstly,the full Markov chains are used to achieve optimal solutions.Secondly,the myopic method together with particle flter（PF）and the challenge match algorithm are also used to achieve sub-optimal solutions,a trade-off between practicability and optimality.The numerical results show that the proposed algorithm provides not only refned model sets but also a good robustness margin and very high accuracy.
基金funded by the State Key Development Program for Basic Research of China(No.2013CB227900)the National High Technology Joint Research Program of China(No.2012BAB13B00)
文摘To solve the problem of water seepage of vertical feeding borehole for solid materials,we established the fluid-solid coupling dynamic model of groundwater flowing in rock mass adjacent to the vertical feeding borehole.Combining with the engineering geological conditions,we built a numeral model to study the influence rule of the aquifer hydraulic pressure and seepage location of feeding borehole on the amount of seepage with fnite element numerical method.The results show that the nonlinear relationship is presented among the amount of seepage,the seepage location and aquifer hydraulic pressure.The higher the aquifer hydraulic pressure is,the closer the distance between seepage location and aquifer is,and the faster the harmful levels of aquifer will grow.In practice,we calculated the allowable seepage of feeding borehole by the optimum moisture content and natural moisture content of backflling materials,and then determined the protection zone of feeding borehole,so the moisture content of backflling materials can be controlled within the scope of optimum moisture content.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.11072117,10802042,and 60904068)the Natural Science Foundation of Zhejiang Province,China (Grant No.Y6100023)+1 种基金the Natural Science Foundation of Ningbo,China (Grant No.2009B21003)the K.C.Wong Magna Fund in Ningbo University,China
文摘A modified coupled map car-following model is proposed, in which two successive vehicle headways in front of the considering vehicle is incorporated into the optimal velocity function. The steady state under certain conditions is obtained. An error system around the steady state is studied further. Moreover, the condition for the state having no traffic jam is derived. A new control scheme is presented to suppress the traffic jam in the modified coupled map car-following model under the open boundary. A control signal including the velocity differences between the following and the considering vehicles, and between the preceding and the considering vehicles is used. The condition under which the traffic jam can be well suppressed is analysed. The results are compared with that presented by t^onishi et al. （the KKH model）. The simulation results show that the temporal behaviour obtained in our model is better than that in the KKH model. The simulation results are in good agreement with the theoretical analysis.
文摘As the performance of an air-cooled condenser is apt to be affected by the fluctuating ambient condition, some difficulties are brought to the use of a steam feeding water pump in an air-cooled unit. This paper introduces a new design of for steam feeding the water pump of an air-cooled unit using the back-pressure steam turbine as the prime motor. Using variable condition analysis on a 600 MW direct air-cooled unit, and with consideration of the effect on the ambient conditions, the feasibility, economy, and adaptability of the design are verified.
文摘Reciprocal oscillographic chronopotentiogram is such a curve that can converts incisions on "(dE/dt)-E" oscillogram into peaks on "(dt/dE)-E" curve. In order to increase the sensitivity, a new technique called feeding back current was added in new circuit of obtaining reciprocal oscillgraphic chronopotentiogram. It can make capacity current be subtracted easily. Using this method, we carry out studying on principle and titration of drug.
文摘This paper studies the problem of robust controller design for linear perturbed continuous stochasticsystems with variance constraints via output feedback. The goal is to design static output feedback controllers suchthat the uncertain system has the desil'ed stability margin and the steady-state variance constraints. The existenceconditions for the desired controllers are discussed, and the analytical expression of these controllers is alsocharacterized. A numerical example is provided to demonstrate the directness and effectiveness of the proposedmethod.
基金supported by Grants from the Research Funds of the Center for Advanced Interdisciplinary Science and Biomedicine of IHM(QYPY20220018)the National Natural Science Foundation of China(31822026,32271063,31500860,and 32100821)the National Science and Technology Innovation 2030 Major Project of China(2021ZD0203900).
文摘In the face of constantly changing environments,the central nervous system(CNS)rapidly and accurately calculates the body's needs,regulates feeding behavior,and maintains energy homeostasis.The arcuate nucleus of the hypothalamus(ARC)plays a key role in this process,serv-ing as a critical brain region for detecting nutrition-related hormones and regulating appetite and energy homeostasis.Agouti-related protein(AgRP)/neuropeptide Y(NPY)neu-rons in the ARC are core elements that interact with other brain regions through a complex appetite-regulating network to comprehensively control energy homeostasis.In this review,we explore the discovery and research progress of AgRP neurons in regulating feeding and energy metabolism.In addition,recent advances in terms of feeding behavior and energy homeostasis,along with the redundant neural mecha-nisms involved in energy metabolism,are discussed.Finally,the challenges and opportunities in the field of neural regula-tion of feeding and energy metabolism are briefly discussed.
基金financially supported by the Green Development and Demonstration Programme(GUDP)(case number 34009-19-1585)。
文摘Background Post-weaning diarrhea(PWD)in piglets,often caused by F4^(+)enterotoxigenic Escherichia coli(ETEC),poses significant challenges in pig production.Traditional solutions like antibiotics and zinc oxide face increasing restrictions due to growing concerns over antibiotic resistance and environmental sustainability.This study investigates the application of bivalent heavy chain variable domain(V_(H)H)constructs(BL1.2 and BL2.2)targeting ETEC virulence factors,administered in feed to mitigate ETEC-induced PWD in weaned piglets.Results The supplementation of BL1.2 and BL2.2 in both mash and pelleted feed significantly reduced the diarrhea incidence and fecal shedding of F4^(+)ETEC in challenged piglets.Pelleted feed containing V_(H)H constructs helped to preserve gut barrier integrity by maintaining levels of the tight junction protein occludin in the small intestine.Additionally,the constructs maintained blood granulocyte counts at a similar level to the non-challenged control group,including neutrophils,and ameliorated the acute phase protein response after challenge.Notably,even at low feed intake immediately after weaning,V_(H)H constructs helped maintain piglet health by mitigating ETEC-induced inflammation and the resulting diarrhea.Conclusions Our findings demonstrated that using V_(H)H constructs as feed additives could serve as an effective strategy to help manage ETEC-associated PWD,by reducing F4^(+)ETEC gut colonization and supporting gut barrier function of weaned piglets.The high stability of these V_(H)H constructs supports their incorporation into industrial feed manufacturing processes,offering a more sustainable preventive strategy compared to traditional antimicrobial interventions,which could contribute to sustainable farming practices.
文摘"Adventures with Dad"(August 2021)After reading the article"Adventures with Dad,"I also have a story to share.Thirty years ago,Iwas a high school student staying home for the Chinese New Year[holiday].
文摘This minireview synthesizes literature on the use of feeding jejunostomy tubes(FJTs)in the postoperative management of gastroesophageal cancer patients.Gastrectomy and esophagectomy remain the primary curative treatments for gastric and esophageal cancers,respectively,but are frequently accompanied by significant postoperative malnutrition,which adversely impacts surgical and oncological outcomes as well as patients’quality of life.To address this,the European Society for Clinical Nutrition and Surgery and the National Comprehensive Cancer Network recommend early enteral feeding through FJT placement following major surgery.While previous studies have demonstrated that FJT is an effective and reliable route for nutritional support,its placement is invasive and carries associated risks.Consequently,many clinicians opt for less invasive alternatives such as total parenteral nutrition or nasogastric tube feeding,although these approaches yield variable results.This review explores the benefits and potential complications of FJT placement,identifies variability in clinical adoption and the absence of standardized protocols,and highlights areas for future research to optimize patient care in this challenging context.
基金funded by research grants from the National Natural Science Foundation of China(Nos.41706142 and 32071615)the China Agriculture Research System of MOF and MARA(No.CARS-49)the Funding for School-Level Research Projects of Yancheng Institute of Technology(No.XJR2021035)。
文摘Microplastic(MP)pollution has spread from the mainland to the ocean.However,Haizhou Bay,which is one of the important land-ocean transition zones,has been reported relatively little about the enrichment of MPs.To provide fundamental data for MP pollution in Haizhou Bay,we studied the occurrence of microplastics in the intestines of 8 species of fish with different habits and feeding modes.The fish intestines were digested with a 10%KOH solution,and MPs are separated with a glass fiber filter.Then,the size,shape,color,and composition of the MPs were analyzed using a stereomicroscope and Fourier transform infrared spectrometer.The results showed the abundance of MP intake ranged from 0.02 items g^(-1) to 0.16 items g^(-1) and the detection rate of MPs ranged from 53.33% to 80% across different fish species.The MP intake in benthic fish and omnivorous fish was significantly higher than that of pelagic fish and predatory fish.Smaller MPs(<0.25 mm)were the dominant types and accounted for 62.50% of the total.The fiber was the prevailing shape of MPs,and the black MPs were the most common,followed by red and yellow ones.Polyethylene terephthalate(PET),polyamide(PA),and polystyrene(PS)were the main components of MPs,accounting for 34.9%,29.9%,and 16.4%,respectively.According to the composition analysis of MPs,the main sources of MPs in fish of Haizhou Bay were attributed to marine aquaculture and port construction.The results are helpful for our better understanding of the status of MP pollution in this area,and further aid in the development of the pointed measures to mitigate and prevent the MP pollution in this ecologically important area.
基金supported by the National Key R&D Program of China(2021YFD1300901)the National Key R&D Young Scientists Project of China(2022YFD1302000)+1 种基金the Education Department of Gansu Province:Outstanding Postgraduate“Innovation Star”,China(2022CXZX-086)the Major Science and Technology Project of Gansu Province,China(22ZD6NC069)。
文摘Feed efficiency(FE)is a crucial economic trait that significantly impacts profitability in intensive sheep production,and can be evaluated by the residual feed intake(RFI)and feed conversion ratio(FCR).However,the underlying genetic mechanisms that underlie FE-related traits in sheep are not fully understood.Herein,we measured the FE-related traits of 1,280 Hu sheep and conducted the phenotype statistics and correlation analysis,the result showcase that there was a large variation for FE-related traits,and RFI was significant positive correlation with average daily feed intake(ADFI)and FCR.Moreover,a genome-wide association study(GWAS)was conducted using whole-genome resequencing data to investigate the genetic associations of ADFI,FCR and RFI.For ADFI and FCR traits,2 and one single nucleotide polymorphisms(SNPs)exceeded the genome-wide significance threshold,whereas ten and 5 SNPs exceeded the suggestive significance threshold.For RFI traits,only 4 SNPs exceeded the suggestive significance threshold.Finally,a total of 8 genes(LOC101121953,LOC101110202,CTNNA3,IZUMO3,PPM1E,YIPF7,ZSCAN12and LOC105603808)were identified as potential candidate genes for FE-related traits.Simultaneously,we further analyzed the effects of 2 candidate SNPs associated with RFI on growth and FE traits in enlarged experimental population,the results demonstrated that these 2 SNPs was not significantly associated with growth traits(P>0.05),but significantly related to RFI traits(P<0.05).These findings will provide valuable reference data and key genetic variants that can be used to effectively select feed-efficient individual in sheep breeding programs.
基金supported by the Capacity Building Project of Local University of Shanghai Municipal Science and Technology Commission(No.10230502900)the Program for Shanghai Collaborative Innovation Center for Cultivating Elite Breeds and Green-culture of Aquaculture animals(No.2021-KJ-02-12)the Innovation Project for Chongming Agriculture Industry from Chongming District Agriculture Commission of Shanghai(No.2022CNKC-01-05)。
文摘The efficiency and mechanism of hydrous iron oxide(HFO)and HFO/calcite mixture to inactivate the phosphorus in the overlying water(OW)/sediment system under the feed adding condition were explored,and the effect of HFO and HFO/calcite mixture addition on the diversity,composition and function of bacterial communities in the sediment was examined.HFO and HFO/calcite mixture direct addition can effectively lower the concentration of soluble reactive phosphorus(RSP)and diffusion gradient in thin film-unstable phosphorus(PD GT)in OW and inactivate the P DGTin the upper sediment.The elimination efficiencies of RSP by the direct HFO and HFO/calcite mixture addition were 48.9%-97.0%and 42.4%-95.4%,respectively.The alteration in the addition mode from the one-time to multiple direct addition was beneficial to the immobilization of RSP and PD GTin OW and P DGTin the upper sediment by HFO and HFO/calcite mixture under the feed input condition in the long run.Permeable fabric wrapping reduced the inactivation efficiency of RSP in OW by HFO and HFO/calcite mixture,but it made the recycling of these materials possible.Most of P immobilized by HFO and HFO/calcite mixture was relatively or very stable.After the HFO and HFO/calcite mixture addition,the composition of bacterial communities in the surface sediment changed.However,the bacterial communities in the amended sediments still can perform good ecological function.Our findings suggest that HFO and HFO/calcite mixture are promising phosphorus-immobilization materials for the inactivation of RSP and PD GTin OW and PD GTin the upper sediment under the feed inputting condition.
基金supported by the research fund of Dankook University in 2025.
文摘The widespread ban on in-feed antibiotics in many regions has driven the search for natural alternatives to maintain health and production efficiency in swine and poultry.Phytogenic feed additives(PFAs)derived from herbs and plant extracts have emerged as promising candidates owing to their antioxidant,anti-inflammatory,and antimicrobial properties.Among these,silymarin—a flavonolignan complex extracted from milk thistle(Silybum marianum)—has attracted particular attention due to its hepatoprotective and growth-promoting activities.This review summarizes the chemical characteristics and mechanisms of action of silymarin/silybin.Also,evidence from both experimental and field studies shows that silymarin improves growth performance,nutrient digestibility,gut health,and reproductive outcomes.Advances in formulation technologies,such as micellization,have been addressed for improved bioavailability of silymarin.Despite these promising results,further long-term field studies and economic evaluations are needed to fully integrate silymarin into commercial animal production systems.
基金supported by the Chinese Natural Science Foundation projects(32272915 and 32472949)National Key Research and Development Programs of China(2023YFD1301003)+1 种基金the Fundamental Research Funds for the Central Universities(2662023DKPY002)Hebei Panshuo Biotechnolog Co.,Ltd.
文摘Background This study was carried out to investigate the individual and combined contamination of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON),and zearalenone(ZEN)in feeds in China between 2021 and 2024.A total of 23,003 feed samples,including 17,489 feedstuff samples and 5,514 complete feed samples,were collected from different provinces of China for mycotoxin analysis.Results The analyzed mycotoxins displayed considerably high contamination in the feed samples,with the individual contamination of AFB_(1),DON,and ZEN were 20.0%–100%,33.3%–100%,and 85.0%–100%,respectively.The average concentrations of AFB_(1),DON,and ZEN were 1.2–728.7μg/kg,106–8,634.8μg/kg,and 18.1–3,341.6μg/kg,respectively.Notably,the rates over China’s safety standards for AFB_(1),DON,and ZEN in raw ingredients were 9.7%,2.7%,and 15.7%,respectively.Meanwhile,3.5%,1.1%,and 8.7%of analyzed complete feeds exceeded China’s safety standards for AFB_(1),DON,and ZEN,respectively.Moreover,the co-contamination rates of AFB_(1),DON,and ZEN in more than 70%of raw ingredients and 87.5%of complete feed products were 60.0%–100%and 61.5%–100%,respectively.Conclusion This study reveals that the feeds in China have commonly been contaminated with AFB_(1),DON,and ZEN alone and their combination during the past four years.These findings highlight the significance of monitoring mycotoxin contaminant levels in domestic animal feed and the importance of carrying out feed administration and remediation strategies for mycotoxin control.
