BACKGROUND Urolithiasisposes challenges in patients with chronic kidney disease(CKD),necessitating careful consideration of surgical interventions due to potential complications.AIM To assess the safety,feasibility,an...BACKGROUND Urolithiasisposes challenges in patients with chronic kidney disease(CKD),necessitating careful consideration of surgical interventions due to potential complications.AIM To assess the safety,feasibility,and efficacy of surgical interventions for urolithiasis in CKD patients.METHODS Systematic review adhering to PRISMA guidelines.Comprehensive searches of PubMed,Scopus,Cochrane Library,Web of Science,and Embase were conducted for studies published from January 2014 to June 2024.Studies involving adult patients(≥18 years)with CKD undergoing surgical interventions for urolithiasis,including randomized controlled trials,cohort studies,case-control studies,and observational studies.Studies involving pediatric patients,those not specifically addressing CKD patients,review articles,commentaries,and editorials.Despite an extensive search,only six studies met the strict inclusion criteria,reflecting the limited available data on this topic.This limitation has been acknowledged and discussed.RESULTS A total of 6 studies met the inclusion criteria,encompassing a diverse range of surgical interventions such as percutaneous nephrolithotomy(PCNL),ureteroscopy(URS),and extracorporeal shock wave lithotripsy(ESWL).Perioperative and postoperative complications varied across studies,with bleeding,infection,and acute kidney injury being the most common.The risk of complications was higher in patients with advanced CKD.Technical success rates were generally high,but feasibility was influenced by patientspecific factors such as CKD stage and comorbidities.Modifications to standard surgical techniques were often necessary.Stone-free rates and recurrence rates varied,with PCNL generally achieving higher stone-free rates compared to URS and ESWL.Long-term outcomes on renal function were inconsistent,highlighting the need for individualized treatment plans.CONCLUSION Surgical interventions for urolithiasis in CKD patients are associated with significant risks but can be effective in achieving stone clearance and symptom relief.The safety,feasibility,and efficacy of these interventions depend on patient-specific factors,necessitating a tailored approach.Further high-quality studies are needed to develop standardized guidelines and improve clinical outcomes in this complex patient population.展开更多
Around the world,there has been a notable shift toward the use of renewable energy technology due to the growing demand for energy and the ongoing depletion of conventional resources,such as fossil fuels.Following thi...Around the world,there has been a notable shift toward the use of renewable energy technology due to the growing demand for energy and the ongoing depletion of conventional resources,such as fossil fuels.Following this worldwide trend,Brunei’s government has initiated several strategic programs aimed at encouraging the establishment of energy from renewable sources in the nation’s energy mix.These initiatives are designed not only to support environmental sustainability but also to make energy from renewable sources increasingly competitive in comparison to more conventional energy sources like gas and oil,which have historically dominated Brunei’s energy market.The optimization of a hybrid energy system that combines diesel generators,solar photovoltaic(PV)panels,and the national power grid is the focus of this study.The objective is to identify the most cost-effective and environmentally sustainable configuration that can reliably meet local energy demands.During optimization,several configuration was tried and tested,including only grid,PV and Grid and PV-generator.HOMER(Hybrid Optimization of Multiple Energy Resources)software,a popular simulation tool that makes it possible to simulate and analyze hybrid energy systems,is utilized in the optimization process.Inside the HOMER Pro optimization,various system configuration is taken into account for the optimization.While simulating,it takes into account different combinations of components such as solar panels,wind turbines and batteries.Later on,it is being ranked by different factors such as net present cost(NPC),Cost of Energy(COE),etc.A comprehensive techno-economic research is carried out to evaluate various system configurations,considering key performance indicators such as total energy generation cost,operational expenditure,and greenhouse gas emissions.The results provide valuable insights into how renewable-based hybrid systems can reduce environmental impact while maintaining economic viability,supporting Brunei’s broader goals of energy diversification and sustainability.The study also emphasizes how such hybrid systems could be scaled for off-grid and rural populations in Brunei,where a dependable electricity supply is still a problem.Furthermore,sensitivity analyses were performed to evaluate the effects of variations in solar irradiation,load demand,and fuel prices on the overall system performance.Policymakers and energy planners can use these insights to help them make data-driven decisions about future investments in infrastructure for renewable energy.展开更多
Bangladesh has achieved notable progress in expanding electricity access nationwide.Nonetheless,remote and topographically challenging regions such as the Chittagong Hill Tracts(CHT)continue to face coverage gaps due ...Bangladesh has achieved notable progress in expanding electricity access nationwide.Nonetheless,remote and topographically challenging regions such as the Chittagong Hill Tracts(CHT)continue to face coverage gaps due to grid extension difficulties.This research investigates the technical feasibility of micro-hydro power(MHP)systems as viable off-grid solutions for rural electrification in CHT.Field surveys conducted across various sites assessed available head and flow rates using GPS-based elevation measurements and portable flowmeters.Seasonal fluctuations were factored into the analysis to ensure year-round operational viability.The study involved estimating power output,selecting appropriate turbine types based on head-flow data,and proposing preliminary plant configurations.Results identify multiple locations with adequate head(2.5 to 10.4 m)and flow rates(0.10 to 0.35 m3/s),capable of generating between 1.5 and 16.5 kW,sufficient for essential rural applications.Based on site-specific head and discharge characteristics,Kaplan and Francis turbines were identified as the most suitable configurations,offering high efficiency for the medium-flow,low-to-medium head environments typical of the studied regions.Despite inherent technical potential,challenges such as seasonal variability,infrastructure complexities,and policy deficiencies remain.This investigation addresses a critical knowledge gap in local renewable energy planning.It offers a data-driven foundation for pilot projects and community-scale electrification initiatives in Bangladesh’s remote mountainous areas.展开更多
Chronic obstructive pulmonary disease(COPD)is a common chronic respiratory disease that severely affects patients’quality of life.Current clinical treatments primarily rely on medication,with limited rehabilitation o...Chronic obstructive pulmonary disease(COPD)is a common chronic respiratory disease that severely affects patients’quality of life.Current clinical treatments primarily rely on medication,with limited rehabilitation options and uncertain efficacy.Home-based exercise rehabilitation,as a non-pharmacological therapy,can promote the improvement of respiratory muscle function and cardiopulmonary endurance,exerting a positive preventive effect on COPD.However,due to factors such as the home environment and lack of health knowledge,COPD patients face numerous difficulties in accepting home-based exercise rehabilitation.This article reviews domestic and international research on the feasibility and effectiveness of home-based exercise rehabilitation for COPD,aiming to provide references for medical workers to better implement home-based exercise rehabilitation for COPD,assist patients in performing rehabilitation exercises at home,improve their quality of life,reduce hospitalization rates,and lower medical costs.展开更多
The integration of 7 Tesla magnetic resonance imaging(7 T MRI)in adult patients has marked a revolutionary stride in radiology.In this article we explore the feasibility of 7 T MRI in paediatric practice,emphasizing i...The integration of 7 Tesla magnetic resonance imaging(7 T MRI)in adult patients has marked a revolutionary stride in radiology.In this article we explore the feasibility of 7 T MRI in paediatric practice,emphasizing its feasibility,applications,challenges,and safety considerations.The heightened resolution and tissue contrast of 7 T MRI offer unprecedented diagnostic accuracy,particularly in neuroimaging.Applications range from neuro-oncology to neonatal brain imaging,showcasing its efficacy in detecting subtle structural abnormalities and providing enhanced insights into neurological conditions.Despite the promise,challenges such as high cost,discomfort,and safety concerns necessitate careful consideration.Research suggests that,with precautions,7 T MRI is feasible in paediatrics,yet ongoing studies and safety assessments are imperative.展开更多
Objective:Precision medicine approaches emphasize the importance of reliable prognostic tools for guiding individualized therapy decisions.In this study,we evaluated the clinical feasibility of the single patient clas...Objective:Precision medicine approaches emphasize the importance of reliable prognostic tools for guiding individualized therapy decisions.In this study,we evaluated the clinical feasibility of the single patient classifier(SPC)test,a new clinical-grade prognostic assay,in stageⅡ-Ⅲgastric cancer patients.Methods:A prospective multicenter study was conducted,involving 237 patients who underwent gastrectomy between September 2019 and August 2020 across nine hospitals.The SPC test was employed to stratify patients into risk groups,and its feasibility and performance were evaluated.The primary endpoint was the proportion of the cases in which the test results were timely delivered before selecting postoperative treatment.Furthermore,3-year disease-free survivals of risk groups were analyzed.Results:The SPC test met the primary endpoint criteria.The 99.5%of SPC tests were timely delivered to hospitals before the postoperative treatment started.In a clinical setting,the median time from the specimen transfer to laboratory to the result delivery to hospital was 4 d.Furthermore,3-year disease-free survivals were significantly different between risk groups classified with SPC tests.Conclusions:This study highlights the SPC test's feasibility in offering crucial information timely delivered for making informed decisions regarding postoperative treatment strategies.It also provides evidence to support the implementation of a future prospective clinical trial aimed at evaluating the clinical utility of the SPC test in guiding personalized treatment decisions for gastric cancer patients.展开更多
BACKGROUND There is still some room for optimizing ambulatory pediatric surgical procedures,and the preoperative and postoperative management quality for pediatric patients needs to be improved.AIM To discuss the safe...BACKGROUND There is still some room for optimizing ambulatory pediatric surgical procedures,and the preoperative and postoperative management quality for pediatric patients needs to be improved.AIM To discuss the safety and feasibility of the enhanced recovery after surgery(ERAS)-based management model for ambulatory pediatric surgical procedures.METHODS We selected 320 pediatric patients undergoing ambulatory surgery from June 2023 to January 2024 at The First People’s Hospital of Liangshan Yi Autonomous Prefecture.Of these,220 received ERAS-based management(research group)and 100 received routine management(control group).General information,postoperative ambulation activities,surgical outcomes(operation time,postoperative gastro-intestinal ventilation time,and hospital stay),postoperative pain visual analogue scale,postoperative complications(incision infection,abdominal distension,fever,nausea,and vomiting),and family satisfaction were compared.RESULTS The general information of the research group(sex,age,disease type,single parent,family history,etc.)was comparable to that of the control group(P>0.05),but the rate of postoperative(2 h,4 h,and 6 h after surgery)ambulation activities was statistically higher(P<0.01),and operation time,postoperative gastrointestinal ventilation time,and hospital stay were markedly shorter(P<0.05).The research group had lower visual analogue scale scores(P<0.01)at 12 h and 24 h after surgery and a lower incidence of total postoperative complications than the control group(P=0.001).The research group had higher family satisfaction than the control group(P=0.007).CONCLUSION The ERAS-based management model was safe and feasible in ambulatory pediatric surgical procedures and worthy of clinical promotion.展开更多
Introduction: Seasonal Malaria Chemoprevention (SMC) aims at preventing malaria in children during the high transmission season. It has been recommended by the WHO since 2013 for children from the age of 3-59 months. ...Introduction: Seasonal Malaria Chemoprevention (SMC) aims at preventing malaria in children during the high transmission season. It has been recommended by the WHO since 2013 for children from the age of 3-59 months. However, despite the impact of this intervention, a peak in the prevalence and incidence of malaria is observed in children from the age of 5-9 years. The aim of this study is to determine from the current literature the feasibility, impact and cost-effectiveness of extending SMC to five cycles and to older children. Methods: A litterature search of PubMed/Medline, NCBI and Google scholar identified 1333 articles. After reading the titles and abstracts by two authors, 24 articles were selected and submitted for full reading. Random control studies on the extension of SMC, malaria, feasibility of SMC, impact of SMC and cost-effectiveness of SMC were selected. A total of 16 articles were included for the qualitative synthesis after excluding 8 studies. Results: Following the summary of the evidence, we conclude that the extension is feasible but will be confronted with the unavailability of older children. The intervention period coincides with field work. SMC is effective in reducing the prevalence and incidence of malaria and the parasite density in children. The financial cost of administering SMC is lower than that of treating a child suffering from malaria. Conclusion: After analysing the information, it was found that the majority of the African population supports the extension of the SMC to the number of cycles and the age group in order to alleviate the high mortality and morbidity rates among children due to malaria.展开更多
Objective:The aim is to develop and verify the feasibility of an adolescent coping model in seasonal flood-prone areas.This coping model supports mental health nurses'practical application to adolescents in flood-...Objective:The aim is to develop and verify the feasibility of an adolescent coping model in seasonal flood-prone areas.This coping model supports mental health nurses'practical application to adolescents in flood-prone areas.Methods:We developed the adolescent coping model based on the processes established in three integrated theories:self-care management for vulnerable populations,coping approaches,and coping with disaster.We conducted semi-structured interviews with 15 participants to explore their perspectives and experiences with flood disasters.We used purposeful sampling for maximum diversity.Data were collected through face-to-face,in-depth interviews.Data were transcribed verbatim,followed by qualitative content analysis.The coping model of adolescents in flood-prone areas was analyzed qualitatively and inductively from the viewpoint of acceptability.Results:The following five categories were identified:(1)coping process post-disaster;(2)coping approach;(3)community power;(4)vulnerability;and(5)self-potential.These domains formed a model for coping model adolescents in seasonal flood-prone areas.Accordingly,our findings showed that the model could be practical for mental health community nursing.Conclusions:Mental health nurses can use the coping model for disaster mental health nursing in adolescents in flood-prone areas.The application of this model will help adolescents increase self-efficacy.展开更多
Transition toward a sustainable,low-carbon energy future requires innovative,integrated solutions.Hybrid solar-hydrogen systems(HSHSs),which combine solar energy harvesting and hydrogen production,have excellent prose...Transition toward a sustainable,low-carbon energy future requires innovative,integrated solutions.Hybrid solar-hydrogen systems(HSHSs),which combine solar energy harvesting and hydrogen production,have excellent prosepects to address challenges related to renewable energy generation,storage,and usage.This article presents an overview of the research on the technical and economic feasibility of HSHSs,aimed at comprehensively articulating their current state,notable advancements,and future research directions.It begins by elucidating solar energy principles and conversion methods and emphasizing the potential of solar energy for hydrogen production.This study then explores the definitions,components,and synergistic integration of HSHSs.Optimized energy conversion and storage methods for efficient hydrogen production and storage are also highlighted.This study reviews the techniques employed for techno-economic evaluations over the last six years,addressing challenges such as the intermittency of solar energy and the efficiency of hydrogen production technologies.This review of the ongoing research provides helpful insights into the technological and economic feasibility of HSHSs.This underscores the necessity of continuous research and development efforts to overcome existing challenges and unlock their full potential.These systems can play a vital role in achieving a cleaner and more resilient energy future by optimizing the system performance,reducing costs,and fostering supportive policy frameworks.展开更多
The“one-stop”student community provides new support for innovation and entrepreneurship education in universities.Integrating innovation and entrepreneurship education into the“one-stop”student community work enri...The“one-stop”student community provides new support for innovation and entrepreneurship education in universities.Integrating innovation and entrepreneurship education into the“one-stop”student community work enriches course materials,integrates teacher resources,improves students’participation in innovation and entrepreneurship,and solves problems such as low student participation,lack of course resources,insufficient teacher resources,and single evaluation methods in traditional classrooms.Through various means such as exploring course resources,innovating management models,and strengthening team construction,the role of“one-stop”student communities in innovation and entrepreneurship education has been fully utilized,promoting the development of innovation and entrepreneurship education.展开更多
The integration of large-scale energy storage batteries and sustainable power generation is a promising way to reduce the consumption of fossil fuels and lower CO_(2) emissions.The significant materials demand for lar...The integration of large-scale energy storage batteries and sustainable power generation is a promising way to reduce the consumption of fossil fuels and lower CO_(2) emissions.The significant materials demand for large-scale energy storage will address the limitation of resource availability.Organics-based aqueous batteries employing organic materials emerge as a promising settlement to face this challenge.Such types of batteries satisfy re-quirements related to elemental availability;inherent safety;cost affordability;technical reliability;and envi-ronmental sustainability meeting the demands of large-scale;long-duration energy storage.展开更多
大规模风电并网导致电力系统惯量和一次调频响应资源减少,大扰动下系统频率安全问题突出。为应对风电不确定性和系统惯量降低的挑战,提出计及风电频率支撑能力和运行风险的鲁棒机组组合(unitcommitment,UC)模型。首先,通过系统发生有功...大规模风电并网导致电力系统惯量和一次调频响应资源减少,大扰动下系统频率安全问题突出。为应对风电不确定性和系统惯量降低的挑战,提出计及风电频率支撑能力和运行风险的鲁棒机组组合(unitcommitment,UC)模型。首先,通过系统发生有功扰动后频率偏差动力学摆动方程建立频率安全的运行约束模型,并嵌入到UC问题中。其次,考虑到风电出力不确定性,提出风电出力鲁棒可行域定义以表征系统接纳风电的安全运行范围,并基于此提出系统运行风险模型。最后,基于两阶段鲁棒优化理论提出计及风电频率支撑能力和运行风险的UC鲁棒优化模型,并采用列和约束生成(column and constraint generation,C&CG)算法求解该模型。在IEEE9和IEEE118节点测试系统进行仿真分析,结果验证了所提模型的有效性。展开更多
文摘BACKGROUND Urolithiasisposes challenges in patients with chronic kidney disease(CKD),necessitating careful consideration of surgical interventions due to potential complications.AIM To assess the safety,feasibility,and efficacy of surgical interventions for urolithiasis in CKD patients.METHODS Systematic review adhering to PRISMA guidelines.Comprehensive searches of PubMed,Scopus,Cochrane Library,Web of Science,and Embase were conducted for studies published from January 2014 to June 2024.Studies involving adult patients(≥18 years)with CKD undergoing surgical interventions for urolithiasis,including randomized controlled trials,cohort studies,case-control studies,and observational studies.Studies involving pediatric patients,those not specifically addressing CKD patients,review articles,commentaries,and editorials.Despite an extensive search,only six studies met the strict inclusion criteria,reflecting the limited available data on this topic.This limitation has been acknowledged and discussed.RESULTS A total of 6 studies met the inclusion criteria,encompassing a diverse range of surgical interventions such as percutaneous nephrolithotomy(PCNL),ureteroscopy(URS),and extracorporeal shock wave lithotripsy(ESWL).Perioperative and postoperative complications varied across studies,with bleeding,infection,and acute kidney injury being the most common.The risk of complications was higher in patients with advanced CKD.Technical success rates were generally high,but feasibility was influenced by patientspecific factors such as CKD stage and comorbidities.Modifications to standard surgical techniques were often necessary.Stone-free rates and recurrence rates varied,with PCNL generally achieving higher stone-free rates compared to URS and ESWL.Long-term outcomes on renal function were inconsistent,highlighting the need for individualized treatment plans.CONCLUSION Surgical interventions for urolithiasis in CKD patients are associated with significant risks but can be effective in achieving stone clearance and symptom relief.The safety,feasibility,and efficacy of these interventions depend on patient-specific factors,necessitating a tailored approach.Further high-quality studies are needed to develop standardized guidelines and improve clinical outcomes in this complex patient population.
基金funded through Deanship of Scientific Research at Northern Border University,Arar,Saudi Arabia—project number“NBU-FFR-2025-3623-06”.
文摘Around the world,there has been a notable shift toward the use of renewable energy technology due to the growing demand for energy and the ongoing depletion of conventional resources,such as fossil fuels.Following this worldwide trend,Brunei’s government has initiated several strategic programs aimed at encouraging the establishment of energy from renewable sources in the nation’s energy mix.These initiatives are designed not only to support environmental sustainability but also to make energy from renewable sources increasingly competitive in comparison to more conventional energy sources like gas and oil,which have historically dominated Brunei’s energy market.The optimization of a hybrid energy system that combines diesel generators,solar photovoltaic(PV)panels,and the national power grid is the focus of this study.The objective is to identify the most cost-effective and environmentally sustainable configuration that can reliably meet local energy demands.During optimization,several configuration was tried and tested,including only grid,PV and Grid and PV-generator.HOMER(Hybrid Optimization of Multiple Energy Resources)software,a popular simulation tool that makes it possible to simulate and analyze hybrid energy systems,is utilized in the optimization process.Inside the HOMER Pro optimization,various system configuration is taken into account for the optimization.While simulating,it takes into account different combinations of components such as solar panels,wind turbines and batteries.Later on,it is being ranked by different factors such as net present cost(NPC),Cost of Energy(COE),etc.A comprehensive techno-economic research is carried out to evaluate various system configurations,considering key performance indicators such as total energy generation cost,operational expenditure,and greenhouse gas emissions.The results provide valuable insights into how renewable-based hybrid systems can reduce environmental impact while maintaining economic viability,supporting Brunei’s broader goals of energy diversification and sustainability.The study also emphasizes how such hybrid systems could be scaled for off-grid and rural populations in Brunei,where a dependable electricity supply is still a problem.Furthermore,sensitivity analyses were performed to evaluate the effects of variations in solar irradiation,load demand,and fuel prices on the overall system performance.Policymakers and energy planners can use these insights to help them make data-driven decisions about future investments in infrastructure for renewable energy.
文摘Bangladesh has achieved notable progress in expanding electricity access nationwide.Nonetheless,remote and topographically challenging regions such as the Chittagong Hill Tracts(CHT)continue to face coverage gaps due to grid extension difficulties.This research investigates the technical feasibility of micro-hydro power(MHP)systems as viable off-grid solutions for rural electrification in CHT.Field surveys conducted across various sites assessed available head and flow rates using GPS-based elevation measurements and portable flowmeters.Seasonal fluctuations were factored into the analysis to ensure year-round operational viability.The study involved estimating power output,selecting appropriate turbine types based on head-flow data,and proposing preliminary plant configurations.Results identify multiple locations with adequate head(2.5 to 10.4 m)and flow rates(0.10 to 0.35 m3/s),capable of generating between 1.5 and 16.5 kW,sufficient for essential rural applications.Based on site-specific head and discharge characteristics,Kaplan and Francis turbines were identified as the most suitable configurations,offering high efficiency for the medium-flow,low-to-medium head environments typical of the studied regions.Despite inherent technical potential,challenges such as seasonal variability,infrastructure complexities,and policy deficiencies remain.This investigation addresses a critical knowledge gap in local renewable energy planning.It offers a data-driven foundation for pilot projects and community-scale electrification initiatives in Bangladesh’s remote mountainous areas.
文摘Chronic obstructive pulmonary disease(COPD)is a common chronic respiratory disease that severely affects patients’quality of life.Current clinical treatments primarily rely on medication,with limited rehabilitation options and uncertain efficacy.Home-based exercise rehabilitation,as a non-pharmacological therapy,can promote the improvement of respiratory muscle function and cardiopulmonary endurance,exerting a positive preventive effect on COPD.However,due to factors such as the home environment and lack of health knowledge,COPD patients face numerous difficulties in accepting home-based exercise rehabilitation.This article reviews domestic and international research on the feasibility and effectiveness of home-based exercise rehabilitation for COPD,aiming to provide references for medical workers to better implement home-based exercise rehabilitation for COPD,assist patients in performing rehabilitation exercises at home,improve their quality of life,reduce hospitalization rates,and lower medical costs.
文摘The integration of 7 Tesla magnetic resonance imaging(7 T MRI)in adult patients has marked a revolutionary stride in radiology.In this article we explore the feasibility of 7 T MRI in paediatric practice,emphasizing its feasibility,applications,challenges,and safety considerations.The heightened resolution and tissue contrast of 7 T MRI offer unprecedented diagnostic accuracy,particularly in neuroimaging.Applications range from neuro-oncology to neonatal brain imaging,showcasing its efficacy in detecting subtle structural abnormalities and providing enhanced insights into neurological conditions.Despite the promise,challenges such as high cost,discomfort,and safety concerns necessitate careful consideration.Research suggests that,with precautions,7 T MRI is feasible in paediatrics,yet ongoing studies and safety assessments are imperative.
基金partial financial support provided by Novomics (Seoul, Korea)
文摘Objective:Precision medicine approaches emphasize the importance of reliable prognostic tools for guiding individualized therapy decisions.In this study,we evaluated the clinical feasibility of the single patient classifier(SPC)test,a new clinical-grade prognostic assay,in stageⅡ-Ⅲgastric cancer patients.Methods:A prospective multicenter study was conducted,involving 237 patients who underwent gastrectomy between September 2019 and August 2020 across nine hospitals.The SPC test was employed to stratify patients into risk groups,and its feasibility and performance were evaluated.The primary endpoint was the proportion of the cases in which the test results were timely delivered before selecting postoperative treatment.Furthermore,3-year disease-free survivals of risk groups were analyzed.Results:The SPC test met the primary endpoint criteria.The 99.5%of SPC tests were timely delivered to hospitals before the postoperative treatment started.In a clinical setting,the median time from the specimen transfer to laboratory to the result delivery to hospital was 4 d.Furthermore,3-year disease-free survivals were significantly different between risk groups classified with SPC tests.Conclusions:This study highlights the SPC test's feasibility in offering crucial information timely delivered for making informed decisions regarding postoperative treatment strategies.It also provides evidence to support the implementation of a future prospective clinical trial aimed at evaluating the clinical utility of the SPC test in guiding personalized treatment decisions for gastric cancer patients.
基金Supported by Liangshan Prefecture Science Research,Development,Promotion and Application Project Application Form,No.17yyjs0011.
文摘BACKGROUND There is still some room for optimizing ambulatory pediatric surgical procedures,and the preoperative and postoperative management quality for pediatric patients needs to be improved.AIM To discuss the safety and feasibility of the enhanced recovery after surgery(ERAS)-based management model for ambulatory pediatric surgical procedures.METHODS We selected 320 pediatric patients undergoing ambulatory surgery from June 2023 to January 2024 at The First People’s Hospital of Liangshan Yi Autonomous Prefecture.Of these,220 received ERAS-based management(research group)and 100 received routine management(control group).General information,postoperative ambulation activities,surgical outcomes(operation time,postoperative gastro-intestinal ventilation time,and hospital stay),postoperative pain visual analogue scale,postoperative complications(incision infection,abdominal distension,fever,nausea,and vomiting),and family satisfaction were compared.RESULTS The general information of the research group(sex,age,disease type,single parent,family history,etc.)was comparable to that of the control group(P>0.05),but the rate of postoperative(2 h,4 h,and 6 h after surgery)ambulation activities was statistically higher(P<0.01),and operation time,postoperative gastrointestinal ventilation time,and hospital stay were markedly shorter(P<0.05).The research group had lower visual analogue scale scores(P<0.01)at 12 h and 24 h after surgery and a lower incidence of total postoperative complications than the control group(P=0.001).The research group had higher family satisfaction than the control group(P=0.007).CONCLUSION The ERAS-based management model was safe and feasible in ambulatory pediatric surgical procedures and worthy of clinical promotion.
文摘Introduction: Seasonal Malaria Chemoprevention (SMC) aims at preventing malaria in children during the high transmission season. It has been recommended by the WHO since 2013 for children from the age of 3-59 months. However, despite the impact of this intervention, a peak in the prevalence and incidence of malaria is observed in children from the age of 5-9 years. The aim of this study is to determine from the current literature the feasibility, impact and cost-effectiveness of extending SMC to five cycles and to older children. Methods: A litterature search of PubMed/Medline, NCBI and Google scholar identified 1333 articles. After reading the titles and abstracts by two authors, 24 articles were selected and submitted for full reading. Random control studies on the extension of SMC, malaria, feasibility of SMC, impact of SMC and cost-effectiveness of SMC were selected. A total of 16 articles were included for the qualitative synthesis after excluding 8 studies. Results: Following the summary of the evidence, we conclude that the extension is feasible but will be confronted with the unavailability of older children. The intervention period coincides with field work. SMC is effective in reducing the prevalence and incidence of malaria and the parasite density in children. The financial cost of administering SMC is lower than that of treating a child suffering from malaria. Conclusion: After analysing the information, it was found that the majority of the African population supports the extension of the SMC to the number of cycles and the age group in order to alleviate the high mortality and morbidity rates among children due to malaria.
文摘Objective:The aim is to develop and verify the feasibility of an adolescent coping model in seasonal flood-prone areas.This coping model supports mental health nurses'practical application to adolescents in flood-prone areas.Methods:We developed the adolescent coping model based on the processes established in three integrated theories:self-care management for vulnerable populations,coping approaches,and coping with disaster.We conducted semi-structured interviews with 15 participants to explore their perspectives and experiences with flood disasters.We used purposeful sampling for maximum diversity.Data were collected through face-to-face,in-depth interviews.Data were transcribed verbatim,followed by qualitative content analysis.The coping model of adolescents in flood-prone areas was analyzed qualitatively and inductively from the viewpoint of acceptability.Results:The following five categories were identified:(1)coping process post-disaster;(2)coping approach;(3)community power;(4)vulnerability;and(5)self-potential.These domains formed a model for coping model adolescents in seasonal flood-prone areas.Accordingly,our findings showed that the model could be practical for mental health community nursing.Conclusions:Mental health nurses can use the coping model for disaster mental health nursing in adolescents in flood-prone areas.The application of this model will help adolescents increase self-efficacy.
文摘Transition toward a sustainable,low-carbon energy future requires innovative,integrated solutions.Hybrid solar-hydrogen systems(HSHSs),which combine solar energy harvesting and hydrogen production,have excellent prosepects to address challenges related to renewable energy generation,storage,and usage.This article presents an overview of the research on the technical and economic feasibility of HSHSs,aimed at comprehensively articulating their current state,notable advancements,and future research directions.It begins by elucidating solar energy principles and conversion methods and emphasizing the potential of solar energy for hydrogen production.This study then explores the definitions,components,and synergistic integration of HSHSs.Optimized energy conversion and storage methods for efficient hydrogen production and storage are also highlighted.This study reviews the techniques employed for techno-economic evaluations over the last six years,addressing challenges such as the intermittency of solar energy and the efficiency of hydrogen production technologies.This review of the ongoing research provides helpful insights into the technological and economic feasibility of HSHSs.This underscores the necessity of continuous research and development efforts to overcome existing challenges and unlock their full potential.These systems can play a vital role in achieving a cleaner and more resilient energy future by optimizing the system performance,reducing costs,and fostering supportive policy frameworks.
基金Jiangsu Province Philosophy and Social Sciences General Project"Exploration of the Path for Cultivating Innovation and Entrepreneurship Ability of Employment-Oriented Applied Undergraduate Talents"。
文摘The“one-stop”student community provides new support for innovation and entrepreneurship education in universities.Integrating innovation and entrepreneurship education into the“one-stop”student community work enriches course materials,integrates teacher resources,improves students’participation in innovation and entrepreneurship,and solves problems such as low student participation,lack of course resources,insufficient teacher resources,and single evaluation methods in traditional classrooms.Through various means such as exploring course resources,innovating management models,and strengthening team construction,the role of“one-stop”student communities in innovation and entrepreneurship education has been fully utilized,promoting the development of innovation and entrepreneurship education.
文摘The integration of large-scale energy storage batteries and sustainable power generation is a promising way to reduce the consumption of fossil fuels and lower CO_(2) emissions.The significant materials demand for large-scale energy storage will address the limitation of resource availability.Organics-based aqueous batteries employing organic materials emerge as a promising settlement to face this challenge.Such types of batteries satisfy re-quirements related to elemental availability;inherent safety;cost affordability;technical reliability;and envi-ronmental sustainability meeting the demands of large-scale;long-duration energy storage.
文摘大规模风电并网导致电力系统惯量和一次调频响应资源减少,大扰动下系统频率安全问题突出。为应对风电不确定性和系统惯量降低的挑战,提出计及风电频率支撑能力和运行风险的鲁棒机组组合(unitcommitment,UC)模型。首先,通过系统发生有功扰动后频率偏差动力学摆动方程建立频率安全的运行约束模型,并嵌入到UC问题中。其次,考虑到风电出力不确定性,提出风电出力鲁棒可行域定义以表征系统接纳风电的安全运行范围,并基于此提出系统运行风险模型。最后,基于两阶段鲁棒优化理论提出计及风电频率支撑能力和运行风险的UC鲁棒优化模型,并采用列和约束生成(column and constraint generation,C&CG)算法求解该模型。在IEEE9和IEEE118节点测试系统进行仿真分析,结果验证了所提模型的有效性。
