Objective To investigate the relationship between carotid intima-media thickness (IMT) and pulse pressure (PP), and evaluate the role of tumor necrosis factor -α(TNF-α) in hypertensive patients. MethodsOne hundred a...Objective To investigate the relationship between carotid intima-media thickness (IMT) and pulse pressure (PP), and evaluate the role of tumor necrosis factor -α(TNF-α) in hypertensive patients. MethodsOne hundred and twenty six essential hypertensive patients were divided into 3 groups according to PP magnitude (group A≤60 mm Hg, group B 61-89 mm Hg, group C≥90 mm Hg). IMT and carotid plaque incidence were assessed by high frequency ultrasonography, and the level of plasma TNF-α was determined by radio-immunity assay.ResultsIMT, incidence rate of carotid plaque and plasma TNF-α were increased in the order of group C>group B>group A (P<0.05). IMT was positively related to PP (r=0.749, P<0.01). The level of plasma TNF-α was correlated positively with IMT and PP, respectively (r=0.497, 0.412, P<0.05).ConclusionPP seems to be a risk factor for assessing subclinical atherosclerosis in hypertensive patients. TNF-α may be involved in the inflammation process of atherosclerotic changes in hypertension.展开更多
本文指出了最新的国际地球参考框架ITRF(International Terrestrial Reference Frame)2005已不能满足当今毫米级地球动态变化监测的需要.提出了利用ITRF2005、SBL/GGFC(Special Bureau for Loading/GlobalGeophysical Fluids Center)和G...本文指出了最新的国际地球参考框架ITRF(International Terrestrial Reference Frame)2005已不能满足当今毫米级地球动态变化监测的需要.提出了利用ITRF2005、SBL/GGFC(Special Bureau for Loading/GlobalGeophysical Fluids Center)和GRACE(Gravity Recovery and Climate Experiment)等卫星的最新成果,构建毫米级地球参考框架的方案,介绍了对其两个关键问题:地壳非线性运动特征△X_R^i(t)和地球质心运动△X_0(t)的空间技术(GPS,VLBI,SLR和GRACE)监测和地球物理因素模制的方法和一些初步结果,并对目前建立和实现毫米级地球参考框架存在的问题和所能达到的精度进行了初步评估.展开更多
文摘Objective To investigate the relationship between carotid intima-media thickness (IMT) and pulse pressure (PP), and evaluate the role of tumor necrosis factor -α(TNF-α) in hypertensive patients. MethodsOne hundred and twenty six essential hypertensive patients were divided into 3 groups according to PP magnitude (group A≤60 mm Hg, group B 61-89 mm Hg, group C≥90 mm Hg). IMT and carotid plaque incidence were assessed by high frequency ultrasonography, and the level of plasma TNF-α was determined by radio-immunity assay.ResultsIMT, incidence rate of carotid plaque and plasma TNF-α were increased in the order of group C>group B>group A (P<0.05). IMT was positively related to PP (r=0.749, P<0.01). The level of plasma TNF-α was correlated positively with IMT and PP, respectively (r=0.497, 0.412, P<0.05).ConclusionPP seems to be a risk factor for assessing subclinical atherosclerosis in hypertensive patients. TNF-α may be involved in the inflammation process of atherosclerotic changes in hypertension.
文摘本文指出了最新的国际地球参考框架ITRF(International Terrestrial Reference Frame)2005已不能满足当今毫米级地球动态变化监测的需要.提出了利用ITRF2005、SBL/GGFC(Special Bureau for Loading/GlobalGeophysical Fluids Center)和GRACE(Gravity Recovery and Climate Experiment)等卫星的最新成果,构建毫米级地球参考框架的方案,介绍了对其两个关键问题:地壳非线性运动特征△X_R^i(t)和地球质心运动△X_0(t)的空间技术(GPS,VLBI,SLR和GRACE)监测和地球物理因素模制的方法和一些初步结果,并对目前建立和实现毫米级地球参考框架存在的问题和所能达到的精度进行了初步评估.
