Psoriasis is a chronic inflammatory skin disease with multiple layers of silvery white scales on the surface of erythema papule as the main clinical characteristics,of which yang-deficiency external cold psoriasis is ...Psoriasis is a chronic inflammatory skin disease with multiple layers of silvery white scales on the surface of erythema papule as the main clinical characteristics,of which yang-deficiency external cold psoriasis is refractory,recurrent and severe in winter and mild in summer,which has a great impact on patients'physical and mental health and quality of life.Traditional Chinese medicine has unique insights in the treatment of psoriasis,both curative effect and safety,have obvious advantages.Based on the concept of"winter disease and summer treatment",long-snake moxibustion gives full play to its functions of warming the kidney,invigorating the marrow,warming the meridians,activating blood circulation and removing blood stasis,so as to restore the deficiency of Yang in patients with psoriasis with external cold syndrome,enhance disease resistance,and prevent psoriasis recurrence or aggravation in winter.Therefore,based on the theory of"winter disease and summer treatment",this paper preliminarily discusses the mechanism of long-snake moxibustion in the prevention and treatment of psoriasis with external cold syndrome of Yang deficiency,and provides new ideas and directions for the prevention and treatment of psoriasis with traditional Chinese medicine.展开更多
Rolling force and rolling moment are prime process parameter of external spline cold rolling.However,the precise theoretical formulae of rolling force and rolling moment are still very fewer,and the determination of t...Rolling force and rolling moment are prime process parameter of external spline cold rolling.However,the precise theoretical formulae of rolling force and rolling moment are still very fewer,and the determination of them depends on experience.In the present study,the mathematical models of rolling force and rolling moment are established based on stress field theory of slip-line.And the isotropic hardening is used to improve the yield criterion.Based on MATLAB program language environment,calculation program is developed according to mathematical models established.The rolling force and rolling moment could be predicted quickly via the calculation program,and then the reliability of the models is validated by FEM.Within the range of module of spline m=0.5-1.5 mm,pressure angle of reference circleα=30.0°-45.0°,and number of spline teeth Z=19-54,the rolling force and rolling moment in rolling process(finishing rolling is excluded)are researched by means of virtualizing orthogonal experiment design.The results of the present study indicate that:the influences of module and number of spline teeth on the maximum rolling force and rolling moment in the process are remarkable;in the case of pressure angle of reference circle is little,module of spline is great,and number of spline teeth is little,the peak value of rolling force in rolling process may appear in the midst of the process;the peak value of rolling moment in rolling process appears in the midst of the process,and then oscillator weaken to a stable value.The results of the present study may provide guidelines for the determination of power of the motor and the design of hydraulic system of special machine,and provide basis for the farther researches on the precise forming process of external spline cold rolling.展开更多
基金National Key Research and Development Program:A Multicenter Randomized Controlled Study on the Treatment of Blood Stasis Syndrome in Psoriasis with the Method of Promoting Blood Circulation and Dispersing Blood Stasis(No.2018YFC1705303)Clinical Study of Long Snake Moxibustion in the Prevention and Treatment of Psoriasis of Yang Deficiency Syndrome Based on the Theory of"Treatment of Winter Disease in Summer"(No.2019SF-312)。
文摘Psoriasis is a chronic inflammatory skin disease with multiple layers of silvery white scales on the surface of erythema papule as the main clinical characteristics,of which yang-deficiency external cold psoriasis is refractory,recurrent and severe in winter and mild in summer,which has a great impact on patients'physical and mental health and quality of life.Traditional Chinese medicine has unique insights in the treatment of psoriasis,both curative effect and safety,have obvious advantages.Based on the concept of"winter disease and summer treatment",long-snake moxibustion gives full play to its functions of warming the kidney,invigorating the marrow,warming the meridians,activating blood circulation and removing blood stasis,so as to restore the deficiency of Yang in patients with psoriasis with external cold syndrome,enhance disease resistance,and prevent psoriasis recurrence or aggravation in winter.Therefore,based on the theory of"winter disease and summer treatment",this paper preliminarily discusses the mechanism of long-snake moxibustion in the prevention and treatment of psoriasis with external cold syndrome of Yang deficiency,and provides new ideas and directions for the prevention and treatment of psoriasis with traditional Chinese medicine.
基金supported by National Natural Science Foundation of China(Grant No.50675145)Shanxi Provincial Key Project of Science and Technology of China(Grant No.2006031147)+1 种基金Shanxi Provincial Innovation Project for Graduate Students of China(Grant No.20061027)Shanxi Provincial Key Project for Studied-abroad Returnee of China
文摘Rolling force and rolling moment are prime process parameter of external spline cold rolling.However,the precise theoretical formulae of rolling force and rolling moment are still very fewer,and the determination of them depends on experience.In the present study,the mathematical models of rolling force and rolling moment are established based on stress field theory of slip-line.And the isotropic hardening is used to improve the yield criterion.Based on MATLAB program language environment,calculation program is developed according to mathematical models established.The rolling force and rolling moment could be predicted quickly via the calculation program,and then the reliability of the models is validated by FEM.Within the range of module of spline m=0.5-1.5 mm,pressure angle of reference circleα=30.0°-45.0°,and number of spline teeth Z=19-54,the rolling force and rolling moment in rolling process(finishing rolling is excluded)are researched by means of virtualizing orthogonal experiment design.The results of the present study indicate that:the influences of module and number of spline teeth on the maximum rolling force and rolling moment in the process are remarkable;in the case of pressure angle of reference circle is little,module of spline is great,and number of spline teeth is little,the peak value of rolling force in rolling process may appear in the midst of the process;the peak value of rolling moment in rolling process appears in the midst of the process,and then oscillator weaken to a stable value.The results of the present study may provide guidelines for the determination of power of the motor and the design of hydraulic system of special machine,and provide basis for the farther researches on the precise forming process of external spline cold rolling.