The existing data mining methods are mostly focused on relational databases and structured data, but not on complex structured data (like in extensible markup language(XML)). By converting XML document type descriptio...The existing data mining methods are mostly focused on relational databases and structured data, but not on complex structured data (like in extensible markup language(XML)). By converting XML document type description to the relational semantic recording XML data relations, and using an XML data mining language, the XML data mining system presents a strategy to mine information on XML.展开更多
In order to solve the problems of high coupling and poor scalability of the traditional monomer early warning release system architecture,multi-level deployment in a complex network environment will lead to high inves...In order to solve the problems of high coupling and poor scalability of the traditional monomer early warning release system architecture,multi-level deployment in a complex network environment will lead to high investment in software and hardware and cannot achieve intensive multi-level deployment.This paper realizes the goal of system scalability by introducing micro service architecture and technology stack and realizes the goal of resource intensification by introducing the idea of a data forwarding agent.The designed architecture scheme has been practically applied in the“Jiangxi emergency early warning information release system software platform(phase I)project”(hereinafter referred to as“provincial emergency”),which meets the needs of flexible deployment of multi-level applications across meteorological wide area network(WAN),business private network of other commissions,offices,and bureaus,government extranet,Internet and other complex networks,and fully verifies the scientificity and rationality of the scheme.It has achieved the goal of intensive and scalable construction of provincial emergencies under the complex network environment,greatly improved the early warning capacity and communication capacity of emergencies and comprehensive disasters,provided a reliable guarantee for disaster prevention and reduction,and provided a reference for the construction of current and future early warning release system and capacity improvement project.展开更多
The paper is devoted to establishing the long-time behavior of solutions to the extensible beam equation with rotational inertia and nonlocal strong damping.Within the theory of asymptotical smoothness,we investigate ...The paper is devoted to establishing the long-time behavior of solutions to the extensible beam equation with rotational inertia and nonlocal strong damping.Within the theory of asymptotical smoothness,we investigate the existence of the attractor by using the contractive function method and more detailed estimates.展开更多
Optical-resolution photoacoustic microscopy is a novel imaging technique that combines the advantages of optical and ultrasound imaging,enabling high-resolution visualization of biological tissues at the micrometer sc...Optical-resolution photoacoustic microscopy is a novel imaging technique that combines the advantages of optical and ultrasound imaging,enabling high-resolution visualization of biological tissues at the micrometer scale.However,the divergence of the excited Gaussian beam limits the depth-of-field of the system to less than 100μm,which hinders accurate three-dimensional imaging of living tissues and restrictsits applicability in biological research.Therefore,there is an urgent need for an effective method to enhance the depth-of-field without altering the hardware configuration.This paper presents a photoacoustic microscopy depth-of-field extension method and system based on three-dimensional continuity and sparsity deconvolution.This method utilizes a depth-varying point spread function and incorporates continuity and sparsity con-straints into the deconvolution process to mitigate the effect of background noise,enhancing the stability and accuracy of the depth-of-field extension.Experimental results using tungsten wire phantoms suggest that the depth-of-field of system can be extended to 650 pm,which is 7.2 times greater than conventional system,while improving the resolution of the defocused region by an average factor of 3.5.Furthermore,experiments on zebrafish and nude mouse ears with irregular topologies demonstrate that the proposed method successfully overcomes image blurring and the loss of structural information due to limited depth-of-field.All the results suggest that the system with higher lateral resolution and enhanced depth-of-field has significant potential for a wide range of practical biomedical applications.展开更多
Agriculture extension and advisory services(AEAS)are integral to smart agricultural systems and play a pivotal role in supporting sustainable agricultural development.The study aimed to assess the role of AEAS in stre...Agriculture extension and advisory services(AEAS)are integral to smart agricultural systems and play a pivotal role in supporting sustainable agricultural development.The study aimed to assess the role of AEAS in strengthening climate-smart coastal farming system to enhance coastal agricultural sustainability.A mixed-methods study was conducted in the southwestern coastal region of Bangladesh in 2023,which involved administering a structured questionnaire and conducing face-to-face interviews with 390 farmers.Perceived role index(PRI)was employed to assess the potential role of AEAS.To forecast the perceived role outcomes,the machine learning model was undertaken by utilizing suitable algorithms.Additionally,feature importance was calculated to underpin the significant factors of perceived role outcomes.The findings showed that coastal farming communities held a comprehensive understanding of the role of AEAS.Key roles included diffusion of agricultural innovations,acting as a bridge between farmers and research organizations,using demonstration techniques to educate farmers,training farmers on food storage,processing,and utilization,and promoting awareness and adoption of best practices.The machine learning model exposed a significant relationship between farmers’socio-economic characteristics and their perception behavior.The results identified that factors like innovativeness,awareness,training exposure,access to AEAS,and access to information significantly influenced how farmers perceived the efficacy of AEAS in promoting a smart coastal farming system.However,farmers confronted multiple constraints in receiving demand-driven services and maintaining coastal farm sustainability.These insights can guide concerned authorities and policy-makers in providing AEAS for the purpose of strengthening climate-smart coastal farming system,particularly with a special focus on capacity building programs and machine learning application.Moreover,the outcomes of this study can assist the authorities of similar coastal systems throughout the world to initiate potential strategies for enhancing region-specific agricultural sustainability.展开更多
The mechanical performance of exceedingly soft materials such as Ag is significantly influenced by various working conditions.Therefore,this study systematically investigates the effects of crack geometry,substrate cr...The mechanical performance of exceedingly soft materials such as Ag is significantly influenced by various working conditions.Therefore,this study systematically investigates the effects of crack geometry,substrate crystal orientation,and indenter shape on crack propagation.The mechanical response of Ag is analyzed using the quasi-continuum(QC)method.A pre-crack with a predefined depth and angle was introduced to initiate fracture behavior.The results show that when the pre-crack height is 50 A,the crack propagates rapidly as the imprint depth increases from0 to 7 A,grows steadily up to 15 A,and then accelerates sharply between 15 and 20 A.For other pre-crack heights,crack propagation occurs at a relatively faster rate.Substrates with[100],[010],and[001]crystal orientations promote crack extension,while the onset of plastic deformation(referred to as the yield point in this study)and the fracture strength both increase with increasing pre-crack height.The yield point,fracture strength,and stress intensity factors are highly sensitive to the pre-crack height.When the pre-crack angle is 90○,the fracture strength reaches its maximum of 0.2%higher than that of the uncracked sample-whereas at 0○,it reaches its minimum,still 53.8%higher than that of the uncracked sample.The sample model is conducted using AutoCAD software.The optimized quasicontinuum(QC)method is used to investigate the effects of different crack geometries,substrate crystal orientations,and indenter shapes on the crack extension of Ag material.Baskes and Dow(FBD)potential is borrowed to describe the interaction forces between Ag-Ag,Ni-Ag,and Ni-Ni.展开更多
In this paper,we offer a new construction of Stefan’s homological spectral sequence for Hopf Galois extensions,by using the double complex argument.Under the faithfully flat condition,a method for computation of Hoch...In this paper,we offer a new construction of Stefan’s homological spectral sequence for Hopf Galois extensions,by using the double complex argument.Under the faithfully flat condition,a method for computation of Hochschild homology is given.展开更多
Mobile communications are reaching out to every aspect of our daily life,necessitating highefficiency data transmission and support for diverse data types and communication scenarios.Polar codes have emerged as a prom...Mobile communications are reaching out to every aspect of our daily life,necessitating highefficiency data transmission and support for diverse data types and communication scenarios.Polar codes have emerged as a promising solution due to their outstanding error-correction performance and low complexity.Unequal error protection(UEP)involves nonuniform error safeguarding for distinct data segments,achieving a fine balance between error resilience and resource allocation,which ultimately enhancing system performance and efficiency.In this paper,we propose a novel class of UEP rateless polar codes.The codes are designed based on matrix extension of polar codes,and elegant mapping and duplication operations are designed to achieve UEP property while preserving the overall performance of conventional polar codes.Superior UEP performance is attained without significant modifications to conventional polar codes,making it straightforward for compatibility with existing polar codes.A theoretical analysis is conducted on the block error rate and throughput efficiency performance.To the best of our knowledge,this work provides the first theoretical performance analysis of UEP rateless polar codes.Simulation results show that the proposed codes significantly outperform existing polar coding schemes in both block error rate and throughput efficiency.展开更多
BACKGROUND With the increasing use of laparoscopic techniques in living-donor kidney transplantation,limitations in donor vessel length,particularly of the right renal vein,pose significant challenges for vascular ana...BACKGROUND With the increasing use of laparoscopic techniques in living-donor kidney transplantation,limitations in donor vessel length,particularly of the right renal vein,pose significant challenges for vascular anastomosis to the recipient’s external iliac vein.These anatomical constraints can complicate graft implantation and increase the risk of postoperative complications.CASE SUMMARY To address the issue of short right renal veins,several surgical strategies have been proposed.In this report,we describe our experience with three cases in which venous extension was successfully achieved using a venous cuff interposition technique during back-table reconstruction.This approach was used to facilitate secure vascular anastomosis and improve graft positioning in anatomically complex transplant scenarios.CONCLUSION Venous cuff interposition represents an effective technique for managing short renal veins in living-donor kidney transplantation.It provides additional length and flexibility,easing anastomotic tension and supporting successful transplantation.展开更多
Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protei...Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protein 4(HE4),a key diagnostic biomarker for ovarian cancer,is involved in fibrotic processes in several non-malignant diseases.Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis,this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC.Methods:A total of 126 patients with gynecological conditions were included and divided into normal,benign,and EOC groups.Tissue stiffness was quantitatively measured and analyzed for its correlation with clinicopathological features.We further investigated the correlation between tumor stiffness and the expression levels of HE4 and fibroblast activation markers(α-smooth muscle actin(α-SMA)and fibroblast activation protein(FAP))in tumor tissues from 22 HGSOC patients.In vitro,primary fibroblasts were treated with recombinant HE4(rHE4)or conditioned media from HE4-knockdown ovarian cancer cells to assess fibroblasts activation and matrix contractility(Collagen gel contraction assays).In vivo,a subcutaneous xenograft model using HE4-knockdown cells was established to evaluate the effects of HE4 suppression on tumor growth and extensive extracellular matrix(ECM)remodeling.Results:Ovarian cancer tissues showed significantly increased stiffness compared to benign/normal groups,showing positive correlation with serum HE4 levels.High-stiffness HGSOC tumors exhibited upregulated expression of HE4,α-SMA,FAP,and collagen I.rHE4 stimulated fibroblast activation and enhanced matrix contractility,whereas HE4 knockdown in cancer cells abrogated these pro-fibrotic effects.In vivo,HE4-silenced xenografts displayed restricted tumor growth accompanied by reduced stromal expression ofα-SMA,FAP,and collagen I.Conclusion:Our findings suggest that HE4 may facilitate ECM remodeling in HGSOC through promoting fibroblast activation and increasing collagen deposition.展开更多
Systemic Functional Linguistics is known to people by its special functionalism and social meaning. The study of Systemic Functional Linguistics is also accepted by more and more people. In addition, it means a lot to...Systemic Functional Linguistics is known to people by its special functionalism and social meaning. The study of Systemic Functional Linguistics is also accepted by more and more people. In addition, it means a lot to the learning of lexis, English writing and extensive reading.展开更多
The continental Asia is mainly composed of three major tectonic regimes,the Tethys,Paleo Asian Ocean,and West Pacific.It underwent multi-stage plate convergences,ocean-continent transformations,and subductions,collisi...The continental Asia is mainly composed of three major tectonic regimes,the Tethys,Paleo Asian Ocean,and West Pacific.It underwent multi-stage plate convergences,ocean-continent transformations,and subductions,collisions and/or collages,and post collisional(orogenic)extensions in Phanerozoic.Tectonic evolution of the Asia brings up a unique fault system and tectonic geomorphological features in the China's Mainland.Also,it provides a geodynamic background for the formation and evolution of metallogeneses and mineral systems,resulting in nonuniform distribution of tectono-metallogenic systems and metallogenic belts.The spatiotemporal distribution of mineral deposits in China and adjacent areas exhibits periodic variation under controlling of the full life Wilson cycle and tectonic evolution,forming the plate convergence-related mineral system in East Asia.Porphyry Cu deposits are mainly related to compressional systems in Paleozoic and early Mesozoic,and more closely related to post-collision extensional settings in late Mesozoic and Cenozoic.Orogenic Au deposits mainly formed in post-orogeny extensional setting.Alkaline rock related rare earth element deposits formed mainly at margins of the North China and Yangtze cratons.Granite-pegmatite Li and other rare metal deposits formed mainly in early Mesozoic,related to Indosinian post-orogeny extension.Tectono-metallogenic systems provide important basis for the prospecting of mineral resources.展开更多
The three most crucial factors for the formation of large and super-large magmatic sulfide deposits are： （1） a large volume of mantle-derived mafic-ultramafic magmas that participated in the formation of the deposi...The three most crucial factors for the formation of large and super-large magmatic sulfide deposits are： （1） a large volume of mantle-derived mafic-ultramafic magmas that participated in the formation of the deposits; （2） fractional crystallization and crustal contamination, particularly the input of sulfur from crustal rocks, resulting in sulfide immiscibility and segregation; and （3） the timing of sulfide concentration in the intrusion. The super-large magmatic Ni-Cu sulfide deposits around the world have been found in small mafic-ultramafic intrusions, except for the Sudbury deposit. Studies in the past decade indicated that the intrusions hosting large and super-large magmatic sulfide deposits occur in magma conduits, such as those in China, including Jinchuan （Gansu）, Yangliuping （Sichuan）, Kalatongke （Xinjiang）, and Hongqiling （Jilin）. Magma conduits as open magma systems provide a perfect environment for extensive concentration of immiscible sulfide melts, which have been found to occur along deep regional faults. The origin of many mantle-derived magmas is closely associated with mantle plumes, intracontinental rifts, or post-collisional extension. Although it has been confirmed that sulfide immiscibility results from crustal contamination, grades of sulfide ores are also related to the nature of the parental magmas, the ratio between silicate magma and immiscible sulfide melt, the reaction between the sulfide melts and newly injected silicate magmas, and fractionation of the sulfide melt. The field relationships of the ore-bearing intrusion and the sulfide ore body are controlled by the geological features of the wall rocks. In this paper, we attempt to demonstrate the general characteristics, formation mechanism,tectonic settings, and indicators of magmatic sulfide deposits occurring in magmatic conduits which would provide guidelines for further exploration.展开更多
The posterior gut of the Drosophila embryo, consisting of hindgut and Malpighian tubules, provides a simple,well-defined system where it is possible to use a genetic approach to define components essential for epithel...The posterior gut of the Drosophila embryo, consisting of hindgut and Malpighian tubules, provides a simple,well-defined system where it is possible to use a genetic approach to define components essential for epithelial morphogenesis.We review here the advantages of Drosophila as a model genetic organism, the morphogenesis of the epithelial structures of the posterior gut, and what is known about the genetic requirements to form these structures.In overview, primordia are patterned by expression of hierarchies of transcription factors; this leads to localized expression of cell signaling molecules, and finally, to the least understood step: modulation of cell adhesion and cell shape. We describe approaches to identify additional genes that are required for morphogenesis of these simple epithelia, particularly those that might play a structural role by affecting cell adhesion and cell shape.展开更多
Multidatabase systems are designed to achieve schema integration and data interoperation among distributed and heterogeneous database systems. But data model heterogeneity and schema heterogeneity make this a challeng...Multidatabase systems are designed to achieve schema integration and data interoperation among distributed and heterogeneous database systems. But data model heterogeneity and schema heterogeneity make this a challenging task. A multidatabase common data model is firstly introduced based on XML, named XML-based Integration Data Model (XIDM), which is suitable for integrating different types of schemas. Then an approach of schema mappings based on XIDM in multidatabase systems has been presented. The mappings include global mappings, dealing with horizontal and vertical partitioning between global schemas and export schemas, and local mappings, processing the transformation between export schemas and local schemas. Finally, the illustration and implementation of schema mappings in a multidatabase prototype - Panorama system are also discussed. The implementation results demonstrate that the XIDM is an efficient model for managing multiple heterogeneous data sources and the approaches of schema mapping based on XIDM behave very well when integrating relational, object-oriented database systems and other file systems.展开更多
The martensite start temperature is a critical parameter for steels with metastable austenite.Although numerous models have been developed to predict the martensite start(Ms)temperature,the complexity of the martensit...The martensite start temperature is a critical parameter for steels with metastable austenite.Although numerous models have been developed to predict the martensite start(Ms)temperature,the complexity of the martensitic transformation greatly limits their performance and extensibility.In this work,we apply deep data mining of thermodynamic calculations and deep learning to develop a generic model for Msprediction.Deep data mining was used to establish a hierarchical database with three levels of information.Then,a convolutional neural network model,which can accurately treat the hierarchical data structure,was used to obtain the final model.By integrating thermodynamic calculations,traditional machine learning and deep learning modeling,the final predictor model shows excellent generalizability and extensibility,i.e.model performance both within and beyond the composition range of the original database.The effects of 15 alloying elements were considered successfully using the proposed methodology.The work suggests that,with the help of deep data mining considering the physical mechanisms,deep learning methods can partially mitigate the challenge with limited data in materials science and provide a means for solving complex problems with small databases.展开更多
Developing CNC measuring method on the base of coordinate machine can makethe best of the hardware resource of CNC system and realize the integration of CAD/CAM/CAT. Based onthe evenly spaced parallel planes scanning,...Developing CNC measuring method on the base of coordinate machine can makethe best of the hardware resource of CNC system and realize the integration of CAD/CAM/CAT. Based onthe evenly spaced parallel planes scanning, a new adaptive digitizing approach for freeform surfacenamely arc length extrapolation is put forward. By this way, the digitizing approach can be addedto the CNC system, while the system's hardware and software are not changed.展开更多
Large-scale magmatism affected the Tongbai-Dabie orogenic belt during post-collisional lateral tectonic extension in the Cretaceous, which was suggested to account for the widespread deformation and migmatization in t...Large-scale magmatism affected the Tongbai-Dabie orogenic belt during post-collisional lateral tectonic extension in the Cretaceous, which was suggested to account for the widespread deformation and migmatization in the Tongbai-Dabie complexes. However, it cannot explain the most deformations in the shear zones. The northwest-southeast shear zones are developed around or wrapped the Tongbai-Dabie complexes. They play an important role for the interpretation of the tectonic evolution of the Tongbai-Dabie orogenic belt. By a systematically observation and description of the geometry and kinematics of these shear zones, we found that the shear zones to the north dip NE and have a uniform sinistral shear sense, the shear zone to the south dips SW and has a uniform dextral shear sense, and the shear zones at the core are sub-horizontal and have a uniform top-to-NW sense of shear. Combining with the comparison of previous and our geochronological studies, we interpret these associations as indicating that these shear zones were originally a single, more flat-lying and sub- horizontal shear zone with a uniform top-to-NW shear sense before the folding-doming of the Tongbai- Dabie complexes and suggest that the Tongbai-Dabie orogenic belt experienced a uniform top-to-NW orogen-paraUel extension in the ductile lithosphere before the widespread magmatism in the Cretaceous.展开更多
In the northwest of the Himalayan-Tibetan Orogen, the ~250 km-long Kongur Shan extensional system in the eastern Pamir was formed during the convergence between the Indian and Asian plates. Tectonic activity of the Ko...In the northwest of the Himalayan-Tibetan Orogen, the ~250 km-long Kongur Shan extensional system in the eastern Pamir was formed during the convergence between the Indian and Asian plates. Tectonic activity of the Kongur Shan normal fault and the Tashkurgan normal fault can help to reveal the origin of east-west extension along the Kongur Shan extensional system. The Kongur Shan fault has been extensively studied, while the Tashkurgan fault calls for systemic research. In this study, low-temperature thermochronology including apatite fission track analysis and apatite and zircon(U-Th)/He analyses is applied to constrain the timing of activity of the Tashkurgan fault. Results indicate that the Tashkurgan fault initiated at 10–5 Ma, and most likely at 6–5 Ma. The footwall of the Tashkurgan fault has been exhumed at an average exhumation rate of 0.6–0.9 mm/a since the initiation of the Tashkurgan fault. Combined with previous research on the Kongur Shan fault, we believe that the origin of east-west extension along the Kongur Shan extensional system was driven by gravitational collapse of over-thickened Pamir crust.展开更多
The Gobi Altai region of southern Mongolia has been in the Eurasian plate interior since the midMesozoic,yet has experienced episodic phases of deformation since that time.In this paper,we document field evidence to c...The Gobi Altai region of southern Mongolia has been in the Eurasian plate interior since the midMesozoic,yet has experienced episodic phases of deformation since that time.In this paper,we document field evidence to characterize and date the intra-plate tectonic history of the Gobi Altai region from the Triassic to the present.To this end,we provide detailed mapping of the structure and stratigraphy of the eastern flanks of Mt.Ih Bogd that contains the widest variety of rock-time units in the area.We carry out geochronological analysis of basaltic lavas and basement granite in the area.We demonstrate that a crystalline basement with a 502 ± 8 Ma granitoid（U/Pb） underwent two phases of basin formation in the Mesozoic.which we date with new40Ar/39Ar lava ages of 218.5 ± 1.5,123.2 ± 0.7 and 124.8 ± 1.2 Ma,respectively.Both phases are linked to deposition of fluvio-lacustrine sediments and trap-like basaltic volcanics,with cumulative thicknesses of 1000-1500 m.Both basins were likely north-facing half-grabens that developed underN-S extension,but were subsequently overthrusted by Paleozoic and older crystalline basement during a less well constrained,but likely mid-Cretaceous phase of N-S shortening and basin inversion.Our results are consistent with recent seismic imaging of rift basins100 km to the NE of the study area where a similar history was reconstructed.The multiple phases of intra-plate deformation appear to have parallel structural trends,most likely due to reactivated Paleozoic basement structures created during the original terrane amalgamation of the Central Asian Orogenic Belt continental crust.This strong basement heterogeneity may predispose it to reactivation,and make it sensitive to changes in the overall stress field of the Eurasian plate driven by forces at its margins and base.Detailed study of Mongolia’s multi-stage tectonic history may thus provide a key proxy for the long-term dynamics of the Eurasian plate.In addition,the repeated reactivation of the Gobi Altai region during the last 200 My supports the contention that non-cratonized continental interior regions composed of Phanerozoic terrane collages are particularly susceptible to fault reactivation,much more than older cratonized continental crust.展开更多
文摘The existing data mining methods are mostly focused on relational databases and structured data, but not on complex structured data (like in extensible markup language(XML)). By converting XML document type description to the relational semantic recording XML data relations, and using an XML data mining language, the XML data mining system presents a strategy to mine information on XML.
文摘In order to solve the problems of high coupling and poor scalability of the traditional monomer early warning release system architecture,multi-level deployment in a complex network environment will lead to high investment in software and hardware and cannot achieve intensive multi-level deployment.This paper realizes the goal of system scalability by introducing micro service architecture and technology stack and realizes the goal of resource intensification by introducing the idea of a data forwarding agent.The designed architecture scheme has been practically applied in the“Jiangxi emergency early warning information release system software platform(phase I)project”(hereinafter referred to as“provincial emergency”),which meets the needs of flexible deployment of multi-level applications across meteorological wide area network(WAN),business private network of other commissions,offices,and bureaus,government extranet,Internet and other complex networks,and fully verifies the scientificity and rationality of the scheme.It has achieved the goal of intensive and scalable construction of provincial emergencies under the complex network environment,greatly improved the early warning capacity and communication capacity of emergencies and comprehensive disasters,provided a reliable guarantee for disaster prevention and reduction,and provided a reference for the construction of current and future early warning release system and capacity improvement project.
基金Supported by the National Natural Science Foundation of China(Grant Nos.1210150211961059)the University Innovation Project of Gansu Province(Grant No.2023B-062).
文摘The paper is devoted to establishing the long-time behavior of solutions to the extensible beam equation with rotational inertia and nonlocal strong damping.Within the theory of asymptotical smoothness,we investigate the existence of the attractor by using the contractive function method and more detailed estimates.
基金supported by the National Key R&D Program of China[Grant No.2022YFC2402400]the National Natural Science Foundation of China[Grant No.62275062]+2 种基金Project of Shandong Innovation and Startup Community of High-end Medical Apparatus and Instruments[Grant Nos.2023-SGTTXM-002 and 2024-SGTTXM-005]the Shandong Province Technology Innovation Guidance Plan(Central Leading Local Science and Technology Development Fund)[Grant No.YDZX2023115]the Taishan Scholar Special Funding Project of Shandong Province,and the Shandong Laboratory of Advanced Biomaterials and Medical Devices in Weihai[Grant No.ZL202402].
文摘Optical-resolution photoacoustic microscopy is a novel imaging technique that combines the advantages of optical and ultrasound imaging,enabling high-resolution visualization of biological tissues at the micrometer scale.However,the divergence of the excited Gaussian beam limits the depth-of-field of the system to less than 100μm,which hinders accurate three-dimensional imaging of living tissues and restrictsits applicability in biological research.Therefore,there is an urgent need for an effective method to enhance the depth-of-field without altering the hardware configuration.This paper presents a photoacoustic microscopy depth-of-field extension method and system based on three-dimensional continuity and sparsity deconvolution.This method utilizes a depth-varying point spread function and incorporates continuity and sparsity con-straints into the deconvolution process to mitigate the effect of background noise,enhancing the stability and accuracy of the depth-of-field extension.Experimental results using tungsten wire phantoms suggest that the depth-of-field of system can be extended to 650 pm,which is 7.2 times greater than conventional system,while improving the resolution of the defocused region by an average factor of 3.5.Furthermore,experiments on zebrafish and nude mouse ears with irregular topologies demonstrate that the proposed method successfully overcomes image blurring and the loss of structural information due to limited depth-of-field.All the results suggest that the system with higher lateral resolution and enhanced depth-of-field has significant potential for a wide range of practical biomedical applications.
基金the Science and Technology Fellowship Trust, Bangladesh
文摘Agriculture extension and advisory services(AEAS)are integral to smart agricultural systems and play a pivotal role in supporting sustainable agricultural development.The study aimed to assess the role of AEAS in strengthening climate-smart coastal farming system to enhance coastal agricultural sustainability.A mixed-methods study was conducted in the southwestern coastal region of Bangladesh in 2023,which involved administering a structured questionnaire and conducing face-to-face interviews with 390 farmers.Perceived role index(PRI)was employed to assess the potential role of AEAS.To forecast the perceived role outcomes,the machine learning model was undertaken by utilizing suitable algorithms.Additionally,feature importance was calculated to underpin the significant factors of perceived role outcomes.The findings showed that coastal farming communities held a comprehensive understanding of the role of AEAS.Key roles included diffusion of agricultural innovations,acting as a bridge between farmers and research organizations,using demonstration techniques to educate farmers,training farmers on food storage,processing,and utilization,and promoting awareness and adoption of best practices.The machine learning model exposed a significant relationship between farmers’socio-economic characteristics and their perception behavior.The results identified that factors like innovativeness,awareness,training exposure,access to AEAS,and access to information significantly influenced how farmers perceived the efficacy of AEAS in promoting a smart coastal farming system.However,farmers confronted multiple constraints in receiving demand-driven services and maintaining coastal farm sustainability.These insights can guide concerned authorities and policy-makers in providing AEAS for the purpose of strengthening climate-smart coastal farming system,particularly with a special focus on capacity building programs and machine learning application.Moreover,the outcomes of this study can assist the authorities of similar coastal systems throughout the world to initiate potential strategies for enhancing region-specific agricultural sustainability.
基金by the Industry–Academia Cooperation Project No.113A00262(Te-Hua Fang).URLs to the sponsor websites are available at:https://www.nstc.gov.tw.
文摘The mechanical performance of exceedingly soft materials such as Ag is significantly influenced by various working conditions.Therefore,this study systematically investigates the effects of crack geometry,substrate crystal orientation,and indenter shape on crack propagation.The mechanical response of Ag is analyzed using the quasi-continuum(QC)method.A pre-crack with a predefined depth and angle was introduced to initiate fracture behavior.The results show that when the pre-crack height is 50 A,the crack propagates rapidly as the imprint depth increases from0 to 7 A,grows steadily up to 15 A,and then accelerates sharply between 15 and 20 A.For other pre-crack heights,crack propagation occurs at a relatively faster rate.Substrates with[100],[010],and[001]crystal orientations promote crack extension,while the onset of plastic deformation(referred to as the yield point in this study)and the fracture strength both increase with increasing pre-crack height.The yield point,fracture strength,and stress intensity factors are highly sensitive to the pre-crack height.When the pre-crack angle is 90○,the fracture strength reaches its maximum of 0.2%higher than that of the uncracked sample-whereas at 0○,it reaches its minimum,still 53.8%higher than that of the uncracked sample.The sample model is conducted using AutoCAD software.The optimized quasicontinuum(QC)method is used to investigate the effects of different crack geometries,substrate crystal orientations,and indenter shapes on the crack extension of Ag material.Baskes and Dow(FBD)potential is borrowed to describe the interaction forces between Ag-Ag,Ni-Ag,and Ni-Ni.
基金Supported by National Natural Science Foundation of China(Grant No.11971418).
文摘In this paper,we offer a new construction of Stefan’s homological spectral sequence for Hopf Galois extensions,by using the double complex argument.Under the faithfully flat condition,a method for computation of Hochschild homology is given.
基金supported by National Natural Science Foundation of China(No.62301008)China Postdoctoral Science Foundation(No.2022M720272)New Cornerstone Science Foundation through the XPLORER PRIZE。
文摘Mobile communications are reaching out to every aspect of our daily life,necessitating highefficiency data transmission and support for diverse data types and communication scenarios.Polar codes have emerged as a promising solution due to their outstanding error-correction performance and low complexity.Unequal error protection(UEP)involves nonuniform error safeguarding for distinct data segments,achieving a fine balance between error resilience and resource allocation,which ultimately enhancing system performance and efficiency.In this paper,we propose a novel class of UEP rateless polar codes.The codes are designed based on matrix extension of polar codes,and elegant mapping and duplication operations are designed to achieve UEP property while preserving the overall performance of conventional polar codes.Superior UEP performance is attained without significant modifications to conventional polar codes,making it straightforward for compatibility with existing polar codes.A theoretical analysis is conducted on the block error rate and throughput efficiency performance.To the best of our knowledge,this work provides the first theoretical performance analysis of UEP rateless polar codes.Simulation results show that the proposed codes significantly outperform existing polar coding schemes in both block error rate and throughput efficiency.
文摘BACKGROUND With the increasing use of laparoscopic techniques in living-donor kidney transplantation,limitations in donor vessel length,particularly of the right renal vein,pose significant challenges for vascular anastomosis to the recipient’s external iliac vein.These anatomical constraints can complicate graft implantation and increase the risk of postoperative complications.CASE SUMMARY To address the issue of short right renal veins,several surgical strategies have been proposed.In this report,we describe our experience with three cases in which venous extension was successfully achieved using a venous cuff interposition technique during back-table reconstruction.This approach was used to facilitate secure vascular anastomosis and improve graft positioning in anatomically complex transplant scenarios.CONCLUSION Venous cuff interposition represents an effective technique for managing short renal veins in living-donor kidney transplantation.It provides additional length and flexibility,easing anastomotic tension and supporting successful transplantation.
文摘Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protein 4(HE4),a key diagnostic biomarker for ovarian cancer,is involved in fibrotic processes in several non-malignant diseases.Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis,this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC.Methods:A total of 126 patients with gynecological conditions were included and divided into normal,benign,and EOC groups.Tissue stiffness was quantitatively measured and analyzed for its correlation with clinicopathological features.We further investigated the correlation between tumor stiffness and the expression levels of HE4 and fibroblast activation markers(α-smooth muscle actin(α-SMA)and fibroblast activation protein(FAP))in tumor tissues from 22 HGSOC patients.In vitro,primary fibroblasts were treated with recombinant HE4(rHE4)or conditioned media from HE4-knockdown ovarian cancer cells to assess fibroblasts activation and matrix contractility(Collagen gel contraction assays).In vivo,a subcutaneous xenograft model using HE4-knockdown cells was established to evaluate the effects of HE4 suppression on tumor growth and extensive extracellular matrix(ECM)remodeling.Results:Ovarian cancer tissues showed significantly increased stiffness compared to benign/normal groups,showing positive correlation with serum HE4 levels.High-stiffness HGSOC tumors exhibited upregulated expression of HE4,α-SMA,FAP,and collagen I.rHE4 stimulated fibroblast activation and enhanced matrix contractility,whereas HE4 knockdown in cancer cells abrogated these pro-fibrotic effects.In vivo,HE4-silenced xenografts displayed restricted tumor growth accompanied by reduced stromal expression ofα-SMA,FAP,and collagen I.Conclusion:Our findings suggest that HE4 may facilitate ECM remodeling in HGSOC through promoting fibroblast activation and increasing collagen deposition.
文摘Systemic Functional Linguistics is known to people by its special functionalism and social meaning. The study of Systemic Functional Linguistics is also accepted by more and more people. In addition, it means a lot to the learning of lexis, English writing and extensive reading.
基金funded by the Deep Geological Survey Project of the China Geological Survey(Grant Nos.DD20230229,DD20230008,DD20160083 and DD20190011)the DREAM―Deep Resource Exploration and Advanced Mining of the National Key Research and Development Program of China(Grant No.2018YFC0603701)。
文摘The continental Asia is mainly composed of three major tectonic regimes,the Tethys,Paleo Asian Ocean,and West Pacific.It underwent multi-stage plate convergences,ocean-continent transformations,and subductions,collisions and/or collages,and post collisional(orogenic)extensions in Phanerozoic.Tectonic evolution of the Asia brings up a unique fault system and tectonic geomorphological features in the China's Mainland.Also,it provides a geodynamic background for the formation and evolution of metallogeneses and mineral systems,resulting in nonuniform distribution of tectono-metallogenic systems and metallogenic belts.The spatiotemporal distribution of mineral deposits in China and adjacent areas exhibits periodic variation under controlling of the full life Wilson cycle and tectonic evolution,forming the plate convergence-related mineral system in East Asia.Porphyry Cu deposits are mainly related to compressional systems in Paleozoic and early Mesozoic,and more closely related to post-collision extensional settings in late Mesozoic and Cenozoic.Orogenic Au deposits mainly formed in post-orogeny extensional setting.Alkaline rock related rare earth element deposits formed mainly at margins of the North China and Yangtze cratons.Granite-pegmatite Li and other rare metal deposits formed mainly in early Mesozoic,related to Indosinian post-orogeny extension.Tectono-metallogenic systems provide important basis for the prospecting of mineral resources.
基金supported by 973 Program(2007CB411408)National Natural Science Foundation of China(NSFC) projects (40730420 and 40973038)Chinese Academy of Sciences(KZCX2-YW-Q04)
文摘The three most crucial factors for the formation of large and super-large magmatic sulfide deposits are： （1） a large volume of mantle-derived mafic-ultramafic magmas that participated in the formation of the deposits; （2） fractional crystallization and crustal contamination, particularly the input of sulfur from crustal rocks, resulting in sulfide immiscibility and segregation; and （3） the timing of sulfide concentration in the intrusion. The super-large magmatic Ni-Cu sulfide deposits around the world have been found in small mafic-ultramafic intrusions, except for the Sudbury deposit. Studies in the past decade indicated that the intrusions hosting large and super-large magmatic sulfide deposits occur in magma conduits, such as those in China, including Jinchuan （Gansu）, Yangliuping （Sichuan）, Kalatongke （Xinjiang）, and Hongqiling （Jilin）. Magma conduits as open magma systems provide a perfect environment for extensive concentration of immiscible sulfide melts, which have been found to occur along deep regional faults. The origin of many mantle-derived magmas is closely associated with mantle plumes, intracontinental rifts, or post-collisional extension. Although it has been confirmed that sulfide immiscibility results from crustal contamination, grades of sulfide ores are also related to the nature of the parental magmas, the ratio between silicate magma and immiscible sulfide melt, the reaction between the sulfide melts and newly injected silicate magmas, and fractionation of the sulfide melt. The field relationships of the ore-bearing intrusion and the sulfide ore body are controlled by the geological features of the wall rocks. In this paper, we attempt to demonstrate the general characteristics, formation mechanism,tectonic settings, and indicators of magmatic sulfide deposits occurring in magmatic conduits which would provide guidelines for further exploration.
文摘The posterior gut of the Drosophila embryo, consisting of hindgut and Malpighian tubules, provides a simple,well-defined system where it is possible to use a genetic approach to define components essential for epithelial morphogenesis.We review here the advantages of Drosophila as a model genetic organism, the morphogenesis of the epithelial structures of the posterior gut, and what is known about the genetic requirements to form these structures.In overview, primordia are patterned by expression of hierarchies of transcription factors; this leads to localized expression of cell signaling molecules, and finally, to the least understood step: modulation of cell adhesion and cell shape. We describe approaches to identify additional genes that are required for morphogenesis of these simple epithelia, particularly those that might play a structural role by affecting cell adhesion and cell shape.
文摘Multidatabase systems are designed to achieve schema integration and data interoperation among distributed and heterogeneous database systems. But data model heterogeneity and schema heterogeneity make this a challenging task. A multidatabase common data model is firstly introduced based on XML, named XML-based Integration Data Model (XIDM), which is suitable for integrating different types of schemas. Then an approach of schema mappings based on XIDM in multidatabase systems has been presented. The mappings include global mappings, dealing with horizontal and vertical partitioning between global schemas and export schemas, and local mappings, processing the transformation between export schemas and local schemas. Finally, the illustration and implementation of schema mappings in a multidatabase prototype - Panorama system are also discussed. The implementation results demonstrate that the XIDM is an efficient model for managing multiple heterogeneous data sources and the approaches of schema mapping based on XIDM behave very well when integrating relational, object-oriented database systems and other file systems.
基金financially supported by the National Natural Science Foundation of China(Nos.51801019 and U1808208)。
文摘The martensite start temperature is a critical parameter for steels with metastable austenite.Although numerous models have been developed to predict the martensite start(Ms)temperature,the complexity of the martensitic transformation greatly limits their performance and extensibility.In this work,we apply deep data mining of thermodynamic calculations and deep learning to develop a generic model for Msprediction.Deep data mining was used to establish a hierarchical database with three levels of information.Then,a convolutional neural network model,which can accurately treat the hierarchical data structure,was used to obtain the final model.By integrating thermodynamic calculations,traditional machine learning and deep learning modeling,the final predictor model shows excellent generalizability and extensibility,i.e.model performance both within and beyond the composition range of the original database.The effects of 15 alloying elements were considered successfully using the proposed methodology.The work suggests that,with the help of deep data mining considering the physical mechanisms,deep learning methods can partially mitigate the challenge with limited data in materials science and provide a means for solving complex problems with small databases.
基金This project is supported by Provincial Key Science and Technology Planning of Zhejiang(No.971111198).
文摘Developing CNC measuring method on the base of coordinate machine can makethe best of the hardware resource of CNC system and realize the integration of CAD/CAM/CAT. Based onthe evenly spaced parallel planes scanning, a new adaptive digitizing approach for freeform surfacenamely arc length extrapolation is put forward. By this way, the digitizing approach can be addedto the CNC system, while the system's hardware and software are not changed.
基金funded by the National Natural Science Foundation of China(Grants.41272222 to C.Z.Song and 41472166 to S.Lin)China Geological Survey(Grants.1212011121116 to S.Lin)a China Scholarship Council scholarship to H.Liu
文摘Large-scale magmatism affected the Tongbai-Dabie orogenic belt during post-collisional lateral tectonic extension in the Cretaceous, which was suggested to account for the widespread deformation and migmatization in the Tongbai-Dabie complexes. However, it cannot explain the most deformations in the shear zones. The northwest-southeast shear zones are developed around or wrapped the Tongbai-Dabie complexes. They play an important role for the interpretation of the tectonic evolution of the Tongbai-Dabie orogenic belt. By a systematically observation and description of the geometry and kinematics of these shear zones, we found that the shear zones to the north dip NE and have a uniform sinistral shear sense, the shear zone to the south dips SW and has a uniform dextral shear sense, and the shear zones at the core are sub-horizontal and have a uniform top-to-NW sense of shear. Combining with the comparison of previous and our geochronological studies, we interpret these associations as indicating that these shear zones were originally a single, more flat-lying and sub- horizontal shear zone with a uniform top-to-NW shear sense before the folding-doming of the Tongbai- Dabie complexes and suggest that the Tongbai-Dabie orogenic belt experienced a uniform top-to-NW orogen-paraUel extension in the ductile lithosphere before the widespread magmatism in the Cretaceous.
基金funded by the National Natural Science Foundation of China (Nos. 41720104003 and 41330207)the National Science and Technology Major Project of China (Nos. 2017ZX05008-001 and 2016ZX05003-001)Chen S Q receives a PhD grant (No. 201706320352) from the China Scholarship Council。
文摘In the northwest of the Himalayan-Tibetan Orogen, the ~250 km-long Kongur Shan extensional system in the eastern Pamir was formed during the convergence between the Indian and Asian plates. Tectonic activity of the Kongur Shan normal fault and the Tashkurgan normal fault can help to reveal the origin of east-west extension along the Kongur Shan extensional system. The Kongur Shan fault has been extensively studied, while the Tashkurgan fault calls for systemic research. In this study, low-temperature thermochronology including apatite fission track analysis and apatite and zircon(U-Th)/He analyses is applied to constrain the timing of activity of the Tashkurgan fault. Results indicate that the Tashkurgan fault initiated at 10–5 Ma, and most likely at 6–5 Ma. The footwall of the Tashkurgan fault has been exhumed at an average exhumation rate of 0.6–0.9 mm/a since the initiation of the Tashkurgan fault. Combined with previous research on the Kongur Shan fault, we believe that the origin of east-west extension along the Kongur Shan extensional system was driven by gravitational collapse of over-thickened Pamir crust.
基金UK NERC Grant NER/D/S/2003/00671 to WDCThe 2005 fieldwork of DJJvH was partly supported by an E.J.Garwood Grant of the Geological Society of London+1 种基金GBS was supported by the Molengraaff Foundation and the KF Hein FoundationDJJvH acknowledges funding through ERC Starting Grant 306810(SINK)and an NWO VIDI grant
文摘The Gobi Altai region of southern Mongolia has been in the Eurasian plate interior since the midMesozoic,yet has experienced episodic phases of deformation since that time.In this paper,we document field evidence to characterize and date the intra-plate tectonic history of the Gobi Altai region from the Triassic to the present.To this end,we provide detailed mapping of the structure and stratigraphy of the eastern flanks of Mt.Ih Bogd that contains the widest variety of rock-time units in the area.We carry out geochronological analysis of basaltic lavas and basement granite in the area.We demonstrate that a crystalline basement with a 502 ± 8 Ma granitoid（U/Pb） underwent two phases of basin formation in the Mesozoic.which we date with new40Ar/39Ar lava ages of 218.5 ± 1.5,123.2 ± 0.7 and 124.8 ± 1.2 Ma,respectively.Both phases are linked to deposition of fluvio-lacustrine sediments and trap-like basaltic volcanics,with cumulative thicknesses of 1000-1500 m.Both basins were likely north-facing half-grabens that developed underN-S extension,but were subsequently overthrusted by Paleozoic and older crystalline basement during a less well constrained,but likely mid-Cretaceous phase of N-S shortening and basin inversion.Our results are consistent with recent seismic imaging of rift basins100 km to the NE of the study area where a similar history was reconstructed.The multiple phases of intra-plate deformation appear to have parallel structural trends,most likely due to reactivated Paleozoic basement structures created during the original terrane amalgamation of the Central Asian Orogenic Belt continental crust.This strong basement heterogeneity may predispose it to reactivation,and make it sensitive to changes in the overall stress field of the Eurasian plate driven by forces at its margins and base.Detailed study of Mongolia’s multi-stage tectonic history may thus provide a key proxy for the long-term dynamics of the Eurasian plate.In addition,the repeated reactivation of the Gobi Altai region during the last 200 My supports the contention that non-cratonized continental interior regions composed of Phanerozoic terrane collages are particularly susceptible to fault reactivation,much more than older cratonized continental crust.
