Objective To assess the reproducibility of whole-body diffusion weighted imaging(WB-DWI) technique in healthy volunteers under normal breathing with background body signal suppression.Methods WB-DWI was performed on 3...Objective To assess the reproducibility of whole-body diffusion weighted imaging(WB-DWI) technique in healthy volunteers under normal breathing with background body signal suppression.Methods WB-DWI was performed on 32 healthy volunteers twice within two-week period using short TI inversion-recovery diffusion-weighted echo-planar imaging sequence and built-in body coil.The volunteers were scanned across six stations continuously covering the entire body from the head to the feet under normal breathing.The bone apparent diffusion coefficient(ADC) and exponential ADC(eADC) of regions of interest(ROIs) were measured.We analyzed correlation of the results using paired-t-test to assess the reproducibility of the WB-DWI technique.Results We were successful in collecting and analyzing data of 64 WB-DWI images.There was no significant difference in bone ADC and eADC of 824 ROIs between the paired observers and paired scans(P>0.05).Most of the images from all stations were of diagnostic quality.Conclusion The measurements of bone ADC and eADC have good reproducibility.WB-DWI technique under normal breathing with background body signal suppression is adequate.展开更多
Background:Almost all of the cases of cerebral alveolar echinococcos are showed T2WI hypointensity,with“coal-like”changes;as multiple and T2WI hypointensity of nodular lesions on magnetic resonance imaging(MRI).Thes...Background:Almost all of the cases of cerebral alveolar echinococcos are showed T2WI hypointensity,with“coal-like”changes;as multiple and T2WI hypointensity of nodular lesions on magnetic resonance imaging(MRI).These imaging findings were also observed in other lesions like metastases.Purpose:To study the MR Diffusion-weighted imaging characteristics of cerebral alveolar echinococcosis and its role in differentiating cerebral alveolar echinococcosis from metastases.Material and methods:A total of thirty-two cerebral alveolar echinococcosis(CAE)and metastases(16 CAE and 16 metastases)were evaluated by conventional and diffusion MRI,respectively.The mean of apparent diffusion coefficient(ADC)and exponential apparent diffusion coefficient(eADC)values from the determined ROI of the solid region,the peripheral edema and control group were calculated.Results:A total of thirty-two cerebral alveolar echinococcosis(CAE)and brain metastases(BM)(16 CAE and 16 metastases)were nodular lesions.The results showed that in solid regions,the mean ADC values of CAE(1.17±0.06)were higher than BM(0.90±0.07)lesions,while the mean eADC values were lower(CAE 0.31±0.02,BM 0.41±0.03).In the peripheral edematous region,the mean ADC values of CAE were higher than BM lesions,but there were no significant difference,whereas,the mean eADC values were opposite.Conclusion:Diffusion MR is a useful tool for the assessment of cerebral alveolar echinococcosis and can help differentiate them from metastases.It also has a potential role in monitoring therapy and early detection of drug resistance.展开更多
文摘Objective To assess the reproducibility of whole-body diffusion weighted imaging(WB-DWI) technique in healthy volunteers under normal breathing with background body signal suppression.Methods WB-DWI was performed on 32 healthy volunteers twice within two-week period using short TI inversion-recovery diffusion-weighted echo-planar imaging sequence and built-in body coil.The volunteers were scanned across six stations continuously covering the entire body from the head to the feet under normal breathing.The bone apparent diffusion coefficient(ADC) and exponential ADC(eADC) of regions of interest(ROIs) were measured.We analyzed correlation of the results using paired-t-test to assess the reproducibility of the WB-DWI technique.Results We were successful in collecting and analyzing data of 64 WB-DWI images.There was no significant difference in bone ADC and eADC of 824 ROIs between the paired observers and paired scans(P>0.05).Most of the images from all stations were of diagnostic quality.Conclusion The measurements of bone ADC and eADC have good reproducibility.WB-DWI technique under normal breathing with background body signal suppression is adequate.
基金supported by grant from the Key Research Development Project Foundation of the Xinjiang Uygur Autonomous Region[grant number 2016B03052].
文摘Background:Almost all of the cases of cerebral alveolar echinococcos are showed T2WI hypointensity,with“coal-like”changes;as multiple and T2WI hypointensity of nodular lesions on magnetic resonance imaging(MRI).These imaging findings were also observed in other lesions like metastases.Purpose:To study the MR Diffusion-weighted imaging characteristics of cerebral alveolar echinococcosis and its role in differentiating cerebral alveolar echinococcosis from metastases.Material and methods:A total of thirty-two cerebral alveolar echinococcosis(CAE)and metastases(16 CAE and 16 metastases)were evaluated by conventional and diffusion MRI,respectively.The mean of apparent diffusion coefficient(ADC)and exponential apparent diffusion coefficient(eADC)values from the determined ROI of the solid region,the peripheral edema and control group were calculated.Results:A total of thirty-two cerebral alveolar echinococcosis(CAE)and brain metastases(BM)(16 CAE and 16 metastases)were nodular lesions.The results showed that in solid regions,the mean ADC values of CAE(1.17±0.06)were higher than BM(0.90±0.07)lesions,while the mean eADC values were lower(CAE 0.31±0.02,BM 0.41±0.03).In the peripheral edematous region,the mean ADC values of CAE were higher than BM lesions,but there were no significant difference,whereas,the mean eADC values were opposite.Conclusion:Diffusion MR is a useful tool for the assessment of cerebral alveolar echinococcosis and can help differentiate them from metastases.It also has a potential role in monitoring therapy and early detection of drug resistance.
