Objective： The aim of this project was to train highly professional and specialized nursing students from medical colleges to adapt to bedside clinical care by exploring and discussing various methods of injection an...Objective： The aim of this project was to train highly professional and specialized nursing students from medical colleges to adapt to bedside clinical care by exploring and discussing various methods of injection and IV infusion in animal experimentation to hone the core professional nursing competencies. Methods： Two classes from the 2012 senior graduating nursing class were randomly selected by a computer to conduct the diversified practical teaching methods based on animal experimentation. A hospital environment was simulated by requiring students to perform different types of injections and practical IV infusion techniques. A comprehensive evaluation of the core professional competencies, as well as other integrated competencies, was conducted to determine the effectiveness of the teaching methods. Results： Two-sampled, pairwise u-tests were performed between the scores of the experimental （nursing class 2） and control （nursing class 1） groups. These findings showed that the overall test scores were significantly higher in the experimental group compared to the control group and that the average P-values for the competencies in various categories were 〈0.01, which indicated statistically significant results. Conclusions： Based on the data from this project, diversified teaching methods for basic nursing training founded on animal experimentation can help nursing students perfect their core professional competencies and improve their overall professional standing. The introduction of animal experimentation requires further verification, and an increased acknowledgement of its benefits through the widespread dissemination of this information.展开更多
A new experimental method is developed to investigate the effect of dissolved substances on the evaporation rate of small water droplets suspended in the atmosphere.The laboratory setup is based on converting a genera...A new experimental method is developed to investigate the effect of dissolved substances on the evaporation rate of small water droplets suspended in the atmosphere.The laboratory setup is based on converting a generated droplet jet of complex structure into a directed flow of evaporating droplets falling in a vertical tube.Images of falling droplets captured by a high-speed camera through a window in the vertical channel wall are used to determine the sizes and velocities of individual droplets.The computational modeling of droplet motion and evaporation proved useful at all stages of the experimental work:from selecting the position of the vertical channel to processing the experimental data.It was found that even a 0.1%mass concentration of the dissolved ionic salt KCl has a considerable effect on decreasing the evaporation rate of the droplets.In contrast,a typical fungicide with a mass concentration of 2.5%has only a slight impact on the evaporation rate.The laboratory results enabled the authors to refine the evaporation model of water droplets to account for the presence of dissolved substances.Modified models of this type are expected to be useful in controling crop spraying and also in other potential applications.展开更多
In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment metho...In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment method. Dynamic analysis of a milling machine, which is newly designed for producing turbine blades, has been conducted by utilizing the modal synthesis method. The finite element model is verified and updated by experimental modal analysis （EMA） of the machine tool. The result gained by modal synthesis method is compared with whole-model finite element method （FEM） result as well. According to the orthogonal experiment method, four configuration parameters of machine tool are considered as four factors for dynamic characteristics. The influence of configuration parameters on the first three natural frequencies is obtained by range analysis. It is pointed out that configuration parameter is the most important factor affecting the fundamental frequency of machine tools, and configuration parameter has less effect on lower-order modes of the system than others. The combination of configuration parameters which makes the fundamental frequency reach the maximum value is provided. Through demonstration, the conclusion can be drawn that the influence of configuration parameters on the natural frequencies of machine tools can be analyzed explicitly by the orthogonal experiment method, which offers a new method for estimating the dynamic characteristics of machine tools.展开更多
This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investiga...This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investigation and preliminary analysis,the reasons for the excavation collapse were the misuse of the soil parameters,over excavation,incorrect installation of steel struts,invalid monitoring data,and inadequate ground improvement.Finally,a small strain constitutive model was used for further analysis.In order to estimate damage efficiently,the orthogonal array(OA) was introduced for screening the key factor in the numerical experiments.Six estimated indexes including deformations and internal forces of the excavation were taken,and the effectiveness of four factors which may cause the collapse was evaluated.Through numerical experiments and interaction analysis,it is found that the deformation and internal force can be well controlled by jet grouting of the subsoil under the final cutting surface,but increasing the improvement ratio of the jet grouting cannot help optimize the excavation behavior efficiently,and without jet grouting and the fourth level struts,the deformation and internal force of the excavation in this case will far surpass the allowable value.展开更多
Almost all the cellular processes in a living system are controlled by proteins:They regulate gene expression,catalyze chemical reactions,transport small molecules across membranes,and transmit signal across membranes...Almost all the cellular processes in a living system are controlled by proteins:They regulate gene expression,catalyze chemical reactions,transport small molecules across membranes,and transmit signal across membranes.Even,a viral infection is often initiated through virus-host protein interactions.Protein-protein interactions(PPIs)are the physical contacts between two or more proteins and they represent complex biological functions.Nowadays,PPIs have been used to construct PPI networks to study complex pathways for revealing the functions of unknown proteins.Scientists have used PPIs to find the molecular basis of certain diseases and also some potential drug targets.In this review,we will discuss how PPI networks are essential to understand the molecular basis of virus-host relationships and several databases which are dedicated to virus-host interaction studies.Here,we present a short but comprehensive review on PPIs,including the experimental and computational methods of finding PPIs,the databases dedicated to virus-host PPIs,and the associated various applications in protein interaction networks of some lethal viruses with their hosts.展开更多
To analyze the spring disturbance torque caused by motionai cable harness in a stabilized platform, the Kirchhoff theory based cable harness model has been previously developed to dynamically simulate the motional cab...To analyze the spring disturbance torque caused by motionai cable harness in a stabilized platform, the Kirchhoff theory based cable harness model has been previously developed to dynamically simulate the motional cable harness. In this paper, this model was validated by comparing the simulation results with the experiment results （ both the spring force and the deformed profile of the motional cable harness）. In the experiment, a special optical measuring instrument based on binocular vision was developed and the motion and deformation of cable harness were measured. A simpli- fied stabilized platform system was constructed, and the absolute value of spring disturbance force during the motion of this simplified frame was obtained by using a force gauge （0. 02 N precision）. The physical parameters of experimental specimen were also measured. The experimental and simulated results showed good agreement. These results should be useful for better motional cable harness layout design and reliable evaluation of the spring disturbance torque.展开更多
This work is an experimental approach based on the method of experimental plans to determine a specific formulation of a resin concrete. In this study, an unsaturated polyester resin （thermosetting resin） was used w...This work is an experimental approach based on the method of experimental plans to determine a specific formulation of a resin concrete. In this study, an unsaturated polyester resin （thermosetting resin） was used with two types of mineral fillers （dune sand and crushed sand）, and with the addition of a marble powder to ensure the continuity of the particle size mixing granular. The lack of the methods for developing this kind of composite materials, had led us to perform an initial experimental approach to define the experimental field, that is to say determine the mass proportions of the various compounds of mixture of our study. In the second approach, we have established and implemented fully experimental plans with three factors namely： factor （1）： sand, factor （2）： resin, factor （3）： marble powder. Test results being the density of polymer concrete and the mechanical resistances. Finally, multi-parameters regression allowed us to determine predictive mathematical models for the different responses of the study. Tests results showed that at three days we got a tensile strength of about 16 MPa with a resin concrete density of 1.9 g/cm3. This shows the advantages of this material.展开更多
DOE （design of experiments） is a systematic, rigorous approach to engineering problem-solving that applies principles and techniques at the data collection stage so as to ensure the generation of valid, defensible, ...DOE （design of experiments） is a systematic, rigorous approach to engineering problem-solving that applies principles and techniques at the data collection stage so as to ensure the generation of valid, defensible, and supportable engineering conclusions. This paper presents a comparison of three different experimental designs （full experimental design, fractional design and Taguchi design） aimed at studying the effects of cutting parameters variations on surface finish. The results revealed that the effects obtained by analyzing both fractional and Taguchi designs were comparable to the main effects and two-level interactions obtained by the full factorial design. Thus, we conclude that full factorial design appear to be reliable and more economical since they permit to reduce by a factor the amount of time and effort required to conduct the experimental design without losing valuable information. Thus, we conclude that full factorial design appear to be reliable and more economical and without losing valuable information.展开更多
In this paper, on the basis of experimental data of two kinds of chemical explosions, the piston-pushing model of spherical blast-waves and the second-order Godunov-type scheme of finite difference methods with high i...In this paper, on the basis of experimental data of two kinds of chemical explosions, the piston-pushing model of spherical blast-waves and the second-order Godunov-type scheme of finite difference methods with high identification to discontinuity are used to the numerical reconstruction of part of an actual hemispherical blast-wave flow field by properly adjusting the moving bounary conditions of a piston. This method is simple and reliable. It is suitable to the evaluation of effects of the blast-wave flow field away from the explosion center.展开更多
Mixed-variable problems are inevitable in engineering. However, few researches pay attention to discrete variables. This paper proposed a mixed-variable experimental design method (ODCD): first, the design variables w...Mixed-variable problems are inevitable in engineering. However, few researches pay attention to discrete variables. This paper proposed a mixed-variable experimental design method (ODCD): first, the design variables were divided into discrete variables and continuous variables;then, the DVD method was employed for handling discrete variables, the LHD method was applied for continuous variables, and finally, a Columnwise-Pairwise Algorithm was used for the overall optimization of the design matrix. Experimental results demonstrated that the ODCD method outperforms in terms of the sample space coverage performance.展开更多
With China gradually attaching importance to the construction of cultivated land quality and expanding the scope of fertilizer extraction from geodetic formula, the role of soil agrochemical analysis in agricultural p...With China gradually attaching importance to the construction of cultivated land quality and expanding the scope of fertilizer extraction from geodetic formula, the role of soil agrochemical analysis in agricultural production has become more and more obvious. Therefore, it is particularly important for soil fertilizer experts to understand the main aspects of soil agrochemical analysis. Soil agrochemical analysis is a key component of agroforestry and production practices. Through the analysis of soil agriculture and forestry, we should be able to fundamentally optimize and improve the current testing process in order to better serve the production practice. Therefore, soil agrochemical analysis in soil plays an important role in the whole process of soil agrochemical analysis. Therefore, it is necessary to emphasize the improvement of experimental analysis methods and to further study possible experimental improvements.展开更多
Despite a multitude of theoretical discussions on China's mixed ownership reform, very few studies have addressed realistic questions concerning the implementation of the reform. The Resolutions of the Third Plenu...Despite a multitude of theoretical discussions on China's mixed ownership reform, very few studies have addressed realistic questions concerning the implementation of the reform. The Resolutions of the Third Plenum of the 18 th CPC Central Committee and other reform strategies have outlined the reform of sectors with natural monopoly, including urban public utility sectors. The question is how mixed ownership reform should be carried out in sectors of natural monopoly, or which public utilities sectors should enjoy priority of mixed ownership reform. To answer this question, this paper employs data of large public utility enterprises in China from 1998 to 2008, and estimates the natural monopoly attribute at the industry level and corporate total factor productivity(TFP) using cost function analysis method excluding the impact of product price factor. Based on the difference-indifferences-in-differences(DDD) method of natural experiment, an empirical test is carried out for the relationship among natural monopoly, mixed ownership reform and corporate productivity. Our results suggest that:(1) Statistically, mixed ownership reform cannot significantly increase corporate TFP in sectors with natural monopoly;(2) mixed ownership reform should not be carried out indiscriminately on a nationwide basis and for all public utilities sectors. Such an attempt of reform without distinguishing natural monopoly and the level of competitiveness is fraught with policy uncertainties;(3) relative to sectors with natural monopoly, corporate productivity in competitive sectors after mixed ownership reform will improve more significantly and enjoy greater "policy dividends" of institutional reform. Therefore, mixed ownership reform should be carried out first in competitive sectors.展开更多
In this paper the main sources causing the scatter of the experimental results of the material parameters are discussed. They can be divided into two parts: one is the experimental errors which are introduced because ...In this paper the main sources causing the scatter of the experimental results of the material parameters are discussed. They can be divided into two parts: one is the experimental errors which are introduced because of the inaccuracy of experimental equipment, the experimental techniques, etc., and the form of the scatter caused by this source is called external distribution. The other is due to the irregularity and inhomogeneity of the material structure and the randomness of deformation process. The scatter caused by this source is inherent and then this form of the scatter is called internal distribution. Obviously the experimental distribution of material parameters combines these two distributions in some way; therefore, it is a sum distribution of the external distribution and the internal distribution. In view of this , a general method used to analyse the influence of the experimental errors on the experimental results is presented, and three criteria used to value this influence are defined. An example in which the fracture toughness KIC is analysed shows that this method is reasonable, convenient and effective.展开更多
To overcome the shortcomings of the traditional passive ranging technology based on image, such as poor ranging accuracy, low reliability and complex system, a new visual passive ranging method based on re-entrant coa...To overcome the shortcomings of the traditional passive ranging technology based on image, such as poor ranging accuracy, low reliability and complex system, a new visual passive ranging method based on re-entrant coaxial optical path is presented. The target image is obtained using double cameras with coaxial optical path. Since there is imaging optical path difference between the cameras, the images are different. In comparison of the image differences, the target range could be reversed. The principle of the ranging method and the ranging model are described. The relationship among parameters in the ranging process is analyzed quantitatively. Meanwhile,the system composition and technical realization scheme are also presented. Also, the principle of the method is verified by the equivalent experiment. The experimental results show that the design scheme is correct and feasible with good robustness. Generally, the ranging error is less than 10% with good convergence. The optical path is designed in a re-entrant mode to reduce the volume and weight of the system. Through the coaxial design,the visual passive range of the targets with any posture can be obtained in real time. The system can be widely used in electro-optical countermeasure and concealed photoelectric detection.展开更多
The parameters of facial skin on human body were measured by Visia-CR,and the weight coefficients of each evaluation index were clarified by the analytic hierarchy process,thus the comprehensive score was calculated.T...The parameters of facial skin on human body were measured by Visia-CR,and the weight coefficients of each evaluation index were clarified by the analytic hierarchy process,thus the comprehensive score was calculated.The influence of four film-forming agents on the comprehensive score at different quality fractions was examined by single factor experiment to determine the level of each factor.In addition,the optimal proportion of the four film-forming agents was selected by combining multi-indicator comprehensive scoring method and orthogonal experiment.The results show that the best combination of the four film-forming agents in the 8 h wear test is A_(2)B_(2)C_(2)D_(1),and the quality fractions of each component are 2%of trimethylsiloxy silicate,1%of polydimethylsiloxane,2%of(acrylate(ester)/poly(dimethylsiloxane)copolymer,cyclopentasiloxane)and 0.5%of VP/hexadecene copolymer.展开更多
demand for faster vessels continues to grow,various high speed vessels have been designed and constructed for military,recreational,and passenger use.Planing vessels,specifically engineered for high-speed travel,requi...demand for faster vessels continues to grow,various high speed vessels have been designed and constructed for military,recreational,and passenger use.Planing vessels,specifically engineered for high-speed travel,require optimization to improve their hydrodynamic performance and stability during design.Reducing resistance and improving longitudinal stability are key challenges in the design of high-speed vessels.Various methods are employed to overcome these challenges,with the use of a transverse step being one of the most common approaches.This study explores the effect of changing the angle of the aft-wise step and incorporates these changes into existing analytical formulas,resulting in new formulas specifically for high-speed vessels equipped with aft-wise steps.This research investigates how the angle of the transverse step affects the hydrodynamic performance and longitudinal stability of high-speed vessels.Based on the results,analytical formulas have been developed to calculate the wetted surface parameters of vessels equipped with an aft-wise transverse step.The study used experimental methods to analyze the vessel's behavior with six different aft-wise transverse step angles of 0°,9°,11°,13°,15°,and 17°at three speeds of 8,10,and 12 m/s.In the experimental tests,the hydrodynamic components of resistance,trim angle,and wetted surface of the vessel were measured.Results indicate that creating an angle in the transverse step substantially improves the hydrodynamic components and longitudinal stability of the vessel.At the optimal angle,the resistance and trim angle of the vessel were reduced by 7.8%and 12.8%,respectively,compared to the base vessel.Additionally,the existing analytical methods for calculating the wetted surface area are more accurate than similar methods.展开更多
Nitrogen oxides(NO_(x))and particulate matter(PM)present significant risks to both human health and environmental sustainability.The Integrated Dust Removal and Denitrification Technology(DRDt)offers a more efficient ...Nitrogen oxides(NO_(x))and particulate matter(PM)present significant risks to both human health and environmental sustainability.The Integrated Dust Removal and Denitrification Technology(DRDt)offers a more efficient and cost-effective solution for achieving ultralow industrial flue gas emissions;however,its effectiveness is undermined by low catalyst load rates and poor stability in filter materials.This study addresses these limitations by modifying conventional PTFE filter media(PTFE-Tim)through the incorporation of sodium alginate(SA)and dopamine(DA)as modifiers,resulting in two new filter materials:PTFE-SA-MOF and PTFE-DA-MOF.By optimizing the parameters of an orthogonal experimental design,we identified the ideal preparation conditions for these composite materials.The addition of SA and DA enhanced the bonding between the catalyst(Mn-Cu-MOF)crystal particles and the PTFE fibers through mechanisms such as ion exchange,hydrogen bonding,and adhesion.Consequently,the catalyst loading rate and stability of the DRDt filters were significantly improved.Specifically,the PTFE-SA-MOF and PTFE-DA-MOF filters achieved high catalyst loading rates of 15.97% and 15.86%,these values represent improvements of 2.53 and 2.51 times,while maintaining excellent stability,with mass retention rates of 98.64% and 98.27%,respectively,over the conventional PTFE-Tim filter.展开更多
This study examines the efficacy of Avicennia marina(AM)leaves as an environmentally sustainable biosorbent for the extraction of methylene blue(MB)dye from wastewater.A hybrid approach of Response Surface Methodology...This study examines the efficacy of Avicennia marina(AM)leaves as an environmentally sustainable biosorbent for the extraction of methylene blue(MB)dye from wastewater.A hybrid approach of Response Surface Methodology(RSM)and Artificial Neural Networks(ANN)was implemented to assess,optimize,and forecast biosorption effectiveness across different operating parameters.The experimental design employed a Central Composite Design(CCD)methodology,focusing on critical parameters including pH,initial dye concentration,temperature,and biosorbent dosage.The ideal biosorption parameters were identified as a temperature of 44.3℃,pH 7.1,a biosorbent dosage of 0.3 grams,and an initial dye concentration of 48.4 mg/L,resulting in a maximum removal efficiency of 84.26%.The ANN model exhibited significant prediction accuracy,so confirming its appropriateness for predicting and enhancing intricate biosorption processes.The findings underscore that AM leaves constitute a cost-efficient,plentiful,and ecologically sustainable resource for wastewater treatment purposes.Furthermore,the amalgamation of RSM and ANN shown significant efficacy in process optimization and forecasting.These findings provide significant insights into the advancement of eco-friendly solutions for the treatment of dye-contaminated water.Subsequent study must prioritize the amplification of the procedure for industrial applications,the execution of ongoing system assessments,and the evaluation of the enduring environmental and economic ramifications of utilizing AM leaves as a biosorbent.展开更多
[Objective] The aim was to explore release characteristics of vinyl chlo- ride-vinyl acetate copolymer controlled-release N fertilizer and the effects on minerat nitrogen in soils. [Method] Vinyl chloride-vinyl acetat...[Objective] The aim was to explore release characteristics of vinyl chlo- ride-vinyl acetate copolymer controlled-release N fertilizer and the effects on minerat nitrogen in soils. [Method] Vinyl chloride-vinyl acetate copolymer and hydroxyl-modi- fied VCNAc were taken as coating materials to prepare slow release fertilizer. Nutri- ent release characteristics of VC/VAc slow release fertilizer was evaluated by water immersion method and the effects of VC/VAc slow release fertilizer on mineral ni- trogen were researched by pot experiment. [Result] The release periods of VC-VAc controlled-release urea and hydroxyl-modified VC/VAc coated urea were 60 and 50 d, respectively. Furthermore, the content of ammonium nitrogen reached the peak on the 30th d and the content of nitrate nitrogen reached the peak on the 60th d in soils in treatments with VCNAc and hydroxyl-modified VC/VAc; the content of nitrate nitrogen rose again on the 120th d in the treatment with VC/VAc. In terms of wheat yield, different treatments showed insignificant differences and rice yield in the treatment with VCNAc was significantly higher than that in the treatment with hy- droxyl-modified VCNAc （P〈0.05）. [Conclusion] The release days of slow controlled- release fertilizer vary upon pot experiment method and water immersion method. Slow controlled-release fertilizer is not suitable for monoculture, due to long fertilizer efficiency, but multiple cropping would be optimal for its role to be fully exploited.展开更多
Widespread usage of bump-type foil journal bearing(BFJB) in oil-free microturbomachinery requires accurate predictions of dynamic performance characteristics, although it remains a challenging issue because BFJB refle...Widespread usage of bump-type foil journal bearing(BFJB) in oil-free microturbomachinery requires accurate predictions of dynamic performance characteristics, although it remains a challenging issue because BFJB reflects nonlinear both structurally and aerodynamically.This paper presented a simple experimental method to semi-directly obtain the minimum film thickness and dynamic stiffness of BFJB using the journal orbit. Numerical calculations and simulations are conducted to validate the experimental method. The micro-deformation and interaction of various foils are taken into consideration to improve the model precision. The results from the numerical model regarding the BFJB dynamic characteristics are compared with the experimental results coming from a dedicated test rig, which shows that the experimental results fluctuate obviously and agree not well with the numerical results at the start stage due to the presence of dry friction at that time, nevertheless, they show fantastic agreement as soon as a gas film is gradually generated to separate the shaft from the top foil. Therefore, the proposed experimental method is effective to predict film thickness and dynamic characteristics during the period from the lift-off time to the land-off time. The dynamic characteristics, along with the journal orbits also can be used to rapidly predict the dynamics behavior of rotor-bearing systems.展开更多
基金supported by 2012 Jiangxi Province Higher Education Reform Research Provincial Research Project(No.JXJG-12-29-3)
文摘Objective： The aim of this project was to train highly professional and specialized nursing students from medical colleges to adapt to bedside clinical care by exploring and discussing various methods of injection and IV infusion in animal experimentation to hone the core professional nursing competencies. Methods： Two classes from the 2012 senior graduating nursing class were randomly selected by a computer to conduct the diversified practical teaching methods based on animal experimentation. A hospital environment was simulated by requiring students to perform different types of injections and practical IV infusion techniques. A comprehensive evaluation of the core professional competencies, as well as other integrated competencies, was conducted to determine the effectiveness of the teaching methods. Results： Two-sampled, pairwise u-tests were performed between the scores of the experimental （nursing class 2） and control （nursing class 1） groups. These findings showed that the overall test scores were significantly higher in the experimental group compared to the control group and that the average P-values for the competencies in various categories were 〈0.01, which indicated statistically significant results. Conclusions： Based on the data from this project, diversified teaching methods for basic nursing training founded on animal experimentation can help nursing students perfect their core professional competencies and improve their overall professional standing. The introduction of animal experimentation requires further verification, and an increased acknowledgement of its benefits through the widespread dissemination of this information.
基金financially supported by the Russian Science Foundation(project No.24-29-00303:https://rscf.ru/project/24-29-00303/,accessed on 01 July 2025).
文摘A new experimental method is developed to investigate the effect of dissolved substances on the evaporation rate of small water droplets suspended in the atmosphere.The laboratory setup is based on converting a generated droplet jet of complex structure into a directed flow of evaporating droplets falling in a vertical tube.Images of falling droplets captured by a high-speed camera through a window in the vertical channel wall are used to determine the sizes and velocities of individual droplets.The computational modeling of droplet motion and evaporation proved useful at all stages of the experimental work:from selecting the position of the vertical channel to processing the experimental data.It was found that even a 0.1%mass concentration of the dissolved ionic salt KCl has a considerable effect on decreasing the evaporation rate of the droplets.In contrast,a typical fungicide with a mass concentration of 2.5%has only a slight impact on the evaporation rate.The laboratory results enabled the authors to refine the evaporation model of water droplets to account for the presence of dissolved substances.Modified models of this type are expected to be useful in controling crop spraying and also in other potential applications.
基金Important National Science & Technology Specific Projects (2009ZX04001-073)National Natural Science Foundation of China (51105025)
文摘In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment method. Dynamic analysis of a milling machine, which is newly designed for producing turbine blades, has been conducted by utilizing the modal synthesis method. The finite element model is verified and updated by experimental modal analysis （EMA） of the machine tool. The result gained by modal synthesis method is compared with whole-model finite element method （FEM） result as well. According to the orthogonal experiment method, four configuration parameters of machine tool are considered as four factors for dynamic characteristics. The influence of configuration parameters on the first three natural frequencies is obtained by range analysis. It is pointed out that configuration parameter is the most important factor affecting the fundamental frequency of machine tools, and configuration parameter has less effect on lower-order modes of the system than others. The combination of configuration parameters which makes the fundamental frequency reach the maximum value is provided. Through demonstration, the conclusion can be drawn that the influence of configuration parameters on the natural frequencies of machine tools can be analyzed explicitly by the orthogonal experiment method, which offers a new method for estimating the dynamic characteristics of machine tools.
基金Project (No. 51078377) supported by the National Natural Science Foundation of China
文摘This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investigation and preliminary analysis,the reasons for the excavation collapse were the misuse of the soil parameters,over excavation,incorrect installation of steel struts,invalid monitoring data,and inadequate ground improvement.Finally,a small strain constitutive model was used for further analysis.In order to estimate damage efficiently,the orthogonal array(OA) was introduced for screening the key factor in the numerical experiments.Six estimated indexes including deformations and internal forces of the excavation were taken,and the effectiveness of four factors which may cause the collapse was evaluated.Through numerical experiments and interaction analysis,it is found that the deformation and internal force can be well controlled by jet grouting of the subsoil under the final cutting surface,but increasing the improvement ratio of the jet grouting cannot help optimize the excavation behavior efficiently,and without jet grouting and the fourth level struts,the deformation and internal force of the excavation in this case will far surpass the allowable value.
基金National Natural Science Foundation of China,No.31971180 and No.11474013.
文摘Almost all the cellular processes in a living system are controlled by proteins:They regulate gene expression,catalyze chemical reactions,transport small molecules across membranes,and transmit signal across membranes.Even,a viral infection is often initiated through virus-host protein interactions.Protein-protein interactions(PPIs)are the physical contacts between two or more proteins and they represent complex biological functions.Nowadays,PPIs have been used to construct PPI networks to study complex pathways for revealing the functions of unknown proteins.Scientists have used PPIs to find the molecular basis of certain diseases and also some potential drug targets.In this review,we will discuss how PPI networks are essential to understand the molecular basis of virus-host relationships and several databases which are dedicated to virus-host interaction studies.Here,we present a short but comprehensive review on PPIs,including the experimental and computational methods of finding PPIs,the databases dedicated to virus-host PPIs,and the associated various applications in protein interaction networks of some lethal viruses with their hosts.
基金Supported by the National Natural Science Foundation of China(50805009)
文摘To analyze the spring disturbance torque caused by motionai cable harness in a stabilized platform, the Kirchhoff theory based cable harness model has been previously developed to dynamically simulate the motional cable harness. In this paper, this model was validated by comparing the simulation results with the experiment results （ both the spring force and the deformed profile of the motional cable harness）. In the experiment, a special optical measuring instrument based on binocular vision was developed and the motion and deformation of cable harness were measured. A simpli- fied stabilized platform system was constructed, and the absolute value of spring disturbance force during the motion of this simplified frame was obtained by using a force gauge （0. 02 N precision）. The physical parameters of experimental specimen were also measured. The experimental and simulated results showed good agreement. These results should be useful for better motional cable harness layout design and reliable evaluation of the spring disturbance torque.
文摘This work is an experimental approach based on the method of experimental plans to determine a specific formulation of a resin concrete. In this study, an unsaturated polyester resin （thermosetting resin） was used with two types of mineral fillers （dune sand and crushed sand）, and with the addition of a marble powder to ensure the continuity of the particle size mixing granular. The lack of the methods for developing this kind of composite materials, had led us to perform an initial experimental approach to define the experimental field, that is to say determine the mass proportions of the various compounds of mixture of our study. In the second approach, we have established and implemented fully experimental plans with three factors namely： factor （1）： sand, factor （2）： resin, factor （3）： marble powder. Test results being the density of polymer concrete and the mechanical resistances. Finally, multi-parameters regression allowed us to determine predictive mathematical models for the different responses of the study. Tests results showed that at three days we got a tensile strength of about 16 MPa with a resin concrete density of 1.9 g/cm3. This shows the advantages of this material.
文摘DOE （design of experiments） is a systematic, rigorous approach to engineering problem-solving that applies principles and techniques at the data collection stage so as to ensure the generation of valid, defensible, and supportable engineering conclusions. This paper presents a comparison of three different experimental designs （full experimental design, fractional design and Taguchi design） aimed at studying the effects of cutting parameters variations on surface finish. The results revealed that the effects obtained by analyzing both fractional and Taguchi designs were comparable to the main effects and two-level interactions obtained by the full factorial design. Thus, we conclude that full factorial design appear to be reliable and more economical since they permit to reduce by a factor the amount of time and effort required to conduct the experimental design without losing valuable information. Thus, we conclude that full factorial design appear to be reliable and more economical and without losing valuable information.
文摘In this paper, on the basis of experimental data of two kinds of chemical explosions, the piston-pushing model of spherical blast-waves and the second-order Godunov-type scheme of finite difference methods with high identification to discontinuity are used to the numerical reconstruction of part of an actual hemispherical blast-wave flow field by properly adjusting the moving bounary conditions of a piston. This method is simple and reliable. It is suitable to the evaluation of effects of the blast-wave flow field away from the explosion center.
文摘Mixed-variable problems are inevitable in engineering. However, few researches pay attention to discrete variables. This paper proposed a mixed-variable experimental design method (ODCD): first, the design variables were divided into discrete variables and continuous variables;then, the DVD method was employed for handling discrete variables, the LHD method was applied for continuous variables, and finally, a Columnwise-Pairwise Algorithm was used for the overall optimization of the design matrix. Experimental results demonstrated that the ODCD method outperforms in terms of the sample space coverage performance.
文摘With China gradually attaching importance to the construction of cultivated land quality and expanding the scope of fertilizer extraction from geodetic formula, the role of soil agrochemical analysis in agricultural production has become more and more obvious. Therefore, it is particularly important for soil fertilizer experts to understand the main aspects of soil agrochemical analysis. Soil agrochemical analysis is a key component of agroforestry and production practices. Through the analysis of soil agriculture and forestry, we should be able to fundamentally optimize and improve the current testing process in order to better serve the production practice. Therefore, soil agrochemical analysis in soil plays an important role in the whole process of soil agrochemical analysis. Therefore, it is necessary to emphasize the improvement of experimental analysis methods and to further study possible experimental improvements.
文摘Despite a multitude of theoretical discussions on China's mixed ownership reform, very few studies have addressed realistic questions concerning the implementation of the reform. The Resolutions of the Third Plenum of the 18 th CPC Central Committee and other reform strategies have outlined the reform of sectors with natural monopoly, including urban public utility sectors. The question is how mixed ownership reform should be carried out in sectors of natural monopoly, or which public utilities sectors should enjoy priority of mixed ownership reform. To answer this question, this paper employs data of large public utility enterprises in China from 1998 to 2008, and estimates the natural monopoly attribute at the industry level and corporate total factor productivity(TFP) using cost function analysis method excluding the impact of product price factor. Based on the difference-indifferences-in-differences(DDD) method of natural experiment, an empirical test is carried out for the relationship among natural monopoly, mixed ownership reform and corporate productivity. Our results suggest that:(1) Statistically, mixed ownership reform cannot significantly increase corporate TFP in sectors with natural monopoly;(2) mixed ownership reform should not be carried out indiscriminately on a nationwide basis and for all public utilities sectors. Such an attempt of reform without distinguishing natural monopoly and the level of competitiveness is fraught with policy uncertainties;(3) relative to sectors with natural monopoly, corporate productivity in competitive sectors after mixed ownership reform will improve more significantly and enjoy greater "policy dividends" of institutional reform. Therefore, mixed ownership reform should be carried out first in competitive sectors.
文摘In this paper the main sources causing the scatter of the experimental results of the material parameters are discussed. They can be divided into two parts: one is the experimental errors which are introduced because of the inaccuracy of experimental equipment, the experimental techniques, etc., and the form of the scatter caused by this source is called external distribution. The other is due to the irregularity and inhomogeneity of the material structure and the randomness of deformation process. The scatter caused by this source is inherent and then this form of the scatter is called internal distribution. Obviously the experimental distribution of material parameters combines these two distributions in some way; therefore, it is a sum distribution of the external distribution and the internal distribution. In view of this , a general method used to analyse the influence of the experimental errors on the experimental results is presented, and three criteria used to value this influence are defined. An example in which the fracture toughness KIC is analysed shows that this method is reasonable, convenient and effective.
基金Supported by the National Basic Research Program of China under Grant No 2014CB340102
文摘To overcome the shortcomings of the traditional passive ranging technology based on image, such as poor ranging accuracy, low reliability and complex system, a new visual passive ranging method based on re-entrant coaxial optical path is presented. The target image is obtained using double cameras with coaxial optical path. Since there is imaging optical path difference between the cameras, the images are different. In comparison of the image differences, the target range could be reversed. The principle of the ranging method and the ranging model are described. The relationship among parameters in the ranging process is analyzed quantitatively. Meanwhile,the system composition and technical realization scheme are also presented. Also, the principle of the method is verified by the equivalent experiment. The experimental results show that the design scheme is correct and feasible with good robustness. Generally, the ranging error is less than 10% with good convergence. The optical path is designed in a re-entrant mode to reduce the volume and weight of the system. Through the coaxial design,the visual passive range of the targets with any posture can be obtained in real time. The system can be widely used in electro-optical countermeasure and concealed photoelectric detection.
文摘The parameters of facial skin on human body were measured by Visia-CR,and the weight coefficients of each evaluation index were clarified by the analytic hierarchy process,thus the comprehensive score was calculated.The influence of four film-forming agents on the comprehensive score at different quality fractions was examined by single factor experiment to determine the level of each factor.In addition,the optimal proportion of the four film-forming agents was selected by combining multi-indicator comprehensive scoring method and orthogonal experiment.The results show that the best combination of the four film-forming agents in the 8 h wear test is A_(2)B_(2)C_(2)D_(1),and the quality fractions of each component are 2%of trimethylsiloxy silicate,1%of polydimethylsiloxane,2%of(acrylate(ester)/poly(dimethylsiloxane)copolymer,cyclopentasiloxane)and 0.5%of VP/hexadecene copolymer.
文摘demand for faster vessels continues to grow,various high speed vessels have been designed and constructed for military,recreational,and passenger use.Planing vessels,specifically engineered for high-speed travel,require optimization to improve their hydrodynamic performance and stability during design.Reducing resistance and improving longitudinal stability are key challenges in the design of high-speed vessels.Various methods are employed to overcome these challenges,with the use of a transverse step being one of the most common approaches.This study explores the effect of changing the angle of the aft-wise step and incorporates these changes into existing analytical formulas,resulting in new formulas specifically for high-speed vessels equipped with aft-wise steps.This research investigates how the angle of the transverse step affects the hydrodynamic performance and longitudinal stability of high-speed vessels.Based on the results,analytical formulas have been developed to calculate the wetted surface parameters of vessels equipped with an aft-wise transverse step.The study used experimental methods to analyze the vessel's behavior with six different aft-wise transverse step angles of 0°,9°,11°,13°,15°,and 17°at three speeds of 8,10,and 12 m/s.In the experimental tests,the hydrodynamic components of resistance,trim angle,and wetted surface of the vessel were measured.Results indicate that creating an angle in the transverse step substantially improves the hydrodynamic components and longitudinal stability of the vessel.At the optimal angle,the resistance and trim angle of the vessel were reduced by 7.8%and 12.8%,respectively,compared to the base vessel.Additionally,the existing analytical methods for calculating the wetted surface area are more accurate than similar methods.
基金financially supported by Natural Science Foundation of Anhui Provincial Department of Education(2022AH050337)State Key Laboratory of Safety and Health for Metal Mines(2022-JSKSSYS-04)the Project of National Key Research and Development Program(2022YFC3901405).
文摘Nitrogen oxides(NO_(x))and particulate matter(PM)present significant risks to both human health and environmental sustainability.The Integrated Dust Removal and Denitrification Technology(DRDt)offers a more efficient and cost-effective solution for achieving ultralow industrial flue gas emissions;however,its effectiveness is undermined by low catalyst load rates and poor stability in filter materials.This study addresses these limitations by modifying conventional PTFE filter media(PTFE-Tim)through the incorporation of sodium alginate(SA)and dopamine(DA)as modifiers,resulting in two new filter materials:PTFE-SA-MOF and PTFE-DA-MOF.By optimizing the parameters of an orthogonal experimental design,we identified the ideal preparation conditions for these composite materials.The addition of SA and DA enhanced the bonding between the catalyst(Mn-Cu-MOF)crystal particles and the PTFE fibers through mechanisms such as ion exchange,hydrogen bonding,and adhesion.Consequently,the catalyst loading rate and stability of the DRDt filters were significantly improved.Specifically,the PTFE-SA-MOF and PTFE-DA-MOF filters achieved high catalyst loading rates of 15.97% and 15.86%,these values represent improvements of 2.53 and 2.51 times,while maintaining excellent stability,with mass retention rates of 98.64% and 98.27%,respectively,over the conventional PTFE-Tim filter.
文摘This study examines the efficacy of Avicennia marina(AM)leaves as an environmentally sustainable biosorbent for the extraction of methylene blue(MB)dye from wastewater.A hybrid approach of Response Surface Methodology(RSM)and Artificial Neural Networks(ANN)was implemented to assess,optimize,and forecast biosorption effectiveness across different operating parameters.The experimental design employed a Central Composite Design(CCD)methodology,focusing on critical parameters including pH,initial dye concentration,temperature,and biosorbent dosage.The ideal biosorption parameters were identified as a temperature of 44.3℃,pH 7.1,a biosorbent dosage of 0.3 grams,and an initial dye concentration of 48.4 mg/L,resulting in a maximum removal efficiency of 84.26%.The ANN model exhibited significant prediction accuracy,so confirming its appropriateness for predicting and enhancing intricate biosorption processes.The findings underscore that AM leaves constitute a cost-efficient,plentiful,and ecologically sustainable resource for wastewater treatment purposes.Furthermore,the amalgamation of RSM and ANN shown significant efficacy in process optimization and forecasting.These findings provide significant insights into the advancement of eco-friendly solutions for the treatment of dye-contaminated water.Subsequent study must prioritize the amplification of the procedure for industrial applications,the execution of ongoing system assessments,and the evaluation of the enduring environmental and economic ramifications of utilizing AM leaves as a biosorbent.
基金Supported by National Department Public Benefit Research Foundation(201203013)Modern Agricultural Industry Technology System(CARS-11-B-15)+2 种基金IPNI Project(JIANGSU-10)Special Fund for Agro-scientific Research in the Public Interest(201003014-1-2)Jiangsu Agriculture S&T Self-Innovation Project[CX(12)3037]~~
文摘[Objective] The aim was to explore release characteristics of vinyl chlo- ride-vinyl acetate copolymer controlled-release N fertilizer and the effects on minerat nitrogen in soils. [Method] Vinyl chloride-vinyl acetate copolymer and hydroxyl-modi- fied VCNAc were taken as coating materials to prepare slow release fertilizer. Nutri- ent release characteristics of VC/VAc slow release fertilizer was evaluated by water immersion method and the effects of VC/VAc slow release fertilizer on mineral ni- trogen were researched by pot experiment. [Result] The release periods of VC-VAc controlled-release urea and hydroxyl-modified VC/VAc coated urea were 60 and 50 d, respectively. Furthermore, the content of ammonium nitrogen reached the peak on the 30th d and the content of nitrate nitrogen reached the peak on the 60th d in soils in treatments with VCNAc and hydroxyl-modified VC/VAc; the content of nitrate nitrogen rose again on the 120th d in the treatment with VC/VAc. In terms of wheat yield, different treatments showed insignificant differences and rice yield in the treatment with VCNAc was significantly higher than that in the treatment with hy- droxyl-modified VCNAc （P〈0.05）. [Conclusion] The release days of slow controlled- release fertilizer vary upon pot experiment method and water immersion method. Slow controlled-release fertilizer is not suitable for monoculture, due to long fertilizer efficiency, but multiple cropping would be optimal for its role to be fully exploited.
基金funded by the Natural Science Foundation of China (No. 51775025, 51205015)China Key Research and Development Plan (No. 2017YFB0102102, 2018YFB0104100)。
文摘Widespread usage of bump-type foil journal bearing(BFJB) in oil-free microturbomachinery requires accurate predictions of dynamic performance characteristics, although it remains a challenging issue because BFJB reflects nonlinear both structurally and aerodynamically.This paper presented a simple experimental method to semi-directly obtain the minimum film thickness and dynamic stiffness of BFJB using the journal orbit. Numerical calculations and simulations are conducted to validate the experimental method. The micro-deformation and interaction of various foils are taken into consideration to improve the model precision. The results from the numerical model regarding the BFJB dynamic characteristics are compared with the experimental results coming from a dedicated test rig, which shows that the experimental results fluctuate obviously and agree not well with the numerical results at the start stage due to the presence of dry friction at that time, nevertheless, they show fantastic agreement as soon as a gas film is gradually generated to separate the shaft from the top foil. Therefore, the proposed experimental method is effective to predict film thickness and dynamic characteristics during the period from the lift-off time to the land-off time. The dynamic characteristics, along with the journal orbits also can be used to rapidly predict the dynamics behavior of rotor-bearing systems.
