Helium sorption cooler technology is a key means to realize highly reliable low-vibration very lowtemperature environments,which have important applications in fields such as quantum computing and space exploration.Th...Helium sorption cooler technology is a key means to realize highly reliable low-vibration very lowtemperature environments,which have important applications in fields such as quantum computing and space exploration.The laboratory designed a superfluid suppression small hole and a multi-ribbed condenser,developed a reliable-performance helium sorption cooler(HSC),and conducted experimental studies.Experimental results show that the prototype can achieve the lowest cooling temperature of 873 mK without load by filling 6MPa helium at room temperature.The low-temperature hold time is 26 h,and the temperature fluctuation is within 0.8 mK.The cooling power of the helium sorption cooler is 1 mW@0.98 K@3.5 h.Experimental results indicate that when the charging pressure is reduced to 4MPa,theminimum temperature decreases to 836mK,and the hold time shortens to 16 h.When the pre-cooling temperature increases from 3.9 to 4.9 K,the hold time is reduced to 3 h.展开更多
Ultrahigh-performance concrete(UHPC)is a groundbreaking kind of concrete that distinguishes itself from conventional concrete through its unique material properties.Understanding and managing the time-dependent charac...Ultrahigh-performance concrete(UHPC)is a groundbreaking kind of concrete that distinguishes itself from conventional concrete through its unique material properties.Understanding and managing the time-dependent characteristics of these materials is essential for their effective use in various construction applications.This study presents an experimental evaluation of the compressive and bending properties of the UHPC incorporating polypropylene,steel,and glass fibers.Based on ACI-211 guidelines,the UHPC mix was designed by using three types of aggregates:limestone,andesite,and quartzite,along with 5%fiber content(at varying percentages of 0,5%,10%,15%,and 20%)relative to the cementitious materials,and three different water-to-cement(w/c)ratios(0.24,0.3,and 0.4)were used.In this research,the compressive and flexural strength tests were conducted.The results show that increasing the values of the fibers significantly enhances the compressive strength of the studied samples.Furthermore,the utilization of fibers markedly improves the bending strength of the samples,demonstrating a strong correlation with the yield resistance of the material.Also,findings show that using steel fibers increases the compressive and bending strength of the tested samples more than polypropylene and glass fibers.For instance,in UHPC samples with 0.4 w/c,the average compressive strength values are 82.2 MPa,70.3 MPa,and 67.1 MPa for steel,polypropylene,and glass fibers,respectively.Also,in the flexural strength test,the modulus of rupture is obtained as an average of 6.24 MPa,5.24 MPa and 4.83 MPa for UHPC samples with steel,polypropylene and glass fibers,respectively.展开更多
BACKGROUND IgE plays a critical role in allergic inflammation and asthma pathogenesis.This study investigates the involvement of IgE cells in asthma exacerbation and evaluates the effectiveness of targeted interventio...BACKGROUND IgE plays a critical role in allergic inflammation and asthma pathogenesis.This study investigates the involvement of IgE cells in asthma exacerbation and evaluates the effectiveness of targeted interventions.AIM To evaluate the role of IgE in the exacerbation of allergic asthma and to determine the clinical efficacy of anti-IgE therapy in improving disease outcomes.Specifically,the study investigates changes in serum IgE levels,lung function,asthma control scores,and the frequency of acute exacerbations among patients receiving standard therapy with or without anti-IgE intervention.METHODS A total of 200 patients diagnosed with moderate to severe asthma were enrolled in this experimental study conducted from April 2024 to April 2025.Participants were randomized to receive either standard asthma therapy or therapy combined with anti-IgE agents.IgE levels and asthma control parameters were monitored.RESULTS Participants receiving anti-IgE treatment demonstrated a significant reduction in serum IgE levels(P<0.001),improved Forced expiratory volume in one second scores,and fewer exacerbation episodes compared to the control group.CONCLUSION IgE cells significantly contribute to asthma severity,and targeted therapy against IgE can improve disease outcomes.These findings underscore the importance of immunomodulatory strategies in asthma management.展开更多
This study aimed to evaluate the feasibility,safety,and efficacy of a noveltranscatheter suture closure system(HaloStitch^(®))for patent foramen ovale(PFO)closure in a swine model.Methods:Thirteen swine underwent...This study aimed to evaluate the feasibility,safety,and efficacy of a noveltranscatheter suture closure system(HaloStitch^(®))for patent foramen ovale(PFO)closure in a swine model.Methods:Thirteen swine underwentexperimental PF0 model creation.All animals received implantationof the transcatheter suture closure system to evaluate procedural success.Comprehensive follow-up over sixmonths included serial ultrasound imaging,histopathological analysis,and gross anatomical exaninationof cardiac specimens.Results:Successful HaloStitch^(®)device implantation was adhieved in 11 of 13 swine.Gross anatomical examination confirrned secure positioning of all sutures in the atrial septum,with noredundancy or thrombus formation.Postoperative ultrasound demonstrated stable suture and staplepositions throughout follow-up,with no evidence of suture breakage,displacement,or thrombus.Stapleswere clearly visualized under ultrasound imaging,Both the atrial septal defect orifice diameter and residualseptal shunt flow velocity decreased significantly during the observation period.Histopathological analysisrevealed partially organized thrombi at the implant head and fibrous connective tissue encapsulation withlocalized inflammatory cell infiltration surrounding the polymer material.Conclsions:The transcathetersuture closure system(HaloStitch^(®))demonstrated feasibility,safety,and biocompatib ility for PFO closure ina swine model,supporting its potential for clinical translation.展开更多
In this paper,experimental and numerical studies of heat transfer in a test local of side H=0.8 m heated from below are presented and compared.All the walls,the rest of the floor and the ceiling are made from plywood ...In this paper,experimental and numerical studies of heat transfer in a test local of side H=0.8 m heated from below are presented and compared.All the walls,the rest of the floor and the ceiling are made from plywood and polystyrene in sandwich form(3 mmplywood-3 cm polystyrene-3 mmplywood)just on one of the vertical walls contained a glazed door(2 H/3×0.15 m).This local is heated during two heating cycles by a square plate of iron the width L=0.6 H,which represents the heat source,its temperature T_(h) is controlled.The plate is heated for two cycles by an adjustable set-point heat source placed just down the center of it.For each cycle,the heat source is switched“on”for 6 h and switched“off”for 6 h.The outdoor air temperature is kept constant at a low temperature T_(c)<T_(h).All measurements are carried out with k-type thermocouples and with flux meters.Results will be qualitatively presented for two cycles of heating in terms of temperatures and heat flux densitiesϕfor various positions of the test local.The temperature evolution of the center and the profile of the temperature along the vertical centerline are compared by two dimensions simulation using the lattice Boltzmann method.The comparison shows a good agreement with a difference that does not exceed±1℃.展开更多
Low damping characteristics have always been a key sticking points in the development of gas bearings.The application of squeeze film dampers can significantly improve the damping performance of gas lubricated bearing...Low damping characteristics have always been a key sticking points in the development of gas bearings.The application of squeeze film dampers can significantly improve the damping performance of gas lubricated bearings.This paper proposed a novel hermetic diaphragm squeeze film damper(HDSFD)for oil-free turbomachinery supported by gas lubricated bearings.Several types of HDSFDs with symmetrical structure were proposed for good damping performance.By considering the compressibility of the damper fluid,based on hydraulic fluid mechanics theory,a dynamic model of HDSFDs under medium is proposed,which successfully reflects the frequency dependence of force coefficients.Based on the dynamic model,the effects of damper fluid viscosity,bulk modulus of damper fluid,thickness of damper fluid film and plunger thickness on the dynamic stiffness and damping of HDSFDs were analyzed.An experimental test rig was assembled and series of experimental studies on HDSFDs were conducted.The damper fluid transverse flow is added to the existing HDSFD concept,which aims to make the dynamic force coefficients independent of frequency.Although the force coefficient is still frequency dependent,the damping coefficient at high frequency excitation with damper fluid supply twice as that without damper fluid supply.The results serve as a benchmark for the calibration of analytical tools under development.展开更多
Experimental study on the fundamental behavior of box shape steel reinforced concrete （SRC） beams was conducted. Seven 1 ： 3 scale model SRC beams were tested to failure. The experimental results indicate that the ...Experimental study on the fundamental behavior of box shape steel reinforced concrete （SRC） beams was conducted. Seven 1 ： 3 scale model SRC beams were tested to failure. The experimental results indicate that the flexural strength increases with the increase of the ratio of flexural reinforcement and the thickness of flange of the shape steel; the shear strength increases with the increase in the thickness of the web of the shape steel. Concrete filled in the box shape steel can prevent the early failure of specimens due to the buckling of the box shape steel, and increase the ultimate load. Measures should be made to strengthen the connection and co-work between the shape steel and the concrete. Formulae for flexural and shear strength of the composite beams are proposed, and the calculated results are in good agreement with the experimental results. In general, the box shape SRC beam is a kind of ductile member, and it is suitable for extensive engineering application.展开更多
This article studies the application of the alternating current field measurement （ACFM） method in defect detection for underwater structures. Numerical model of the ACFM system is built for structure surface defect...This article studies the application of the alternating current field measurement （ACFM） method in defect detection for underwater structures. Numerical model of the ACFM system is built for structure surface defect detection in seawater environment. Finite element simulation is performed to investigate rules and characteristics of the electromagnetic signal distribution in the defected area. In respect of the simulation results, underwater artificial crack detection experiments are designed and conducted for the ACFM system. The experiment results show that the ACFM system can detect cracks in underwater structures and the detection accuracy is higher than 85%. This can meet the engineering requirement of underwater structure defect detection. The results in this article can be applied to establish technical foundation for the optimization and development of ACFM based underwater structure defects detection system.展开更多
A new technique was introduced for sand stabilization and re-vegetation by use of lignin sand stabilizing material(LSSM). LSSM is a reconstructed organic compound with lignin as the most dominant component from the ex...A new technique was introduced for sand stabilization and re-vegetation by use of lignin sand stabilizing material(LSSM). LSSM is a reconstructed organic compound with lignin as the most dominant component from the extracts of black-liquor issued by straw pulp paper mills. Unlike the polyvinyl acetate or foamed asphalt commonly used for dune stabilization, the new material is plant-friendly and can be used with virescence actions simultaneously. The field experimental study was conducted since 2001 in China's Northwest Ningxia Hui Autonomous Region and has been proved that LSSM is effective in stabilizing the fugitive dunes, making the arenaceous plants survive and the bare dune vegetative. The advisable solution concentration is 2% and the optimal field spraying quantity is 2 5 L/m^2 The soil nutrients of the stabilized and greened dune, such as organic matter, available phosphorous and total nitrogen are all increased compared with the control treatment, which is certainly helpful to the growth of arenaceous plants. The technique is worthwhile to be popularized because it is provided not only a new method for desertification control but also an outlet for cleaning contaminants issued from the straw paper mills.展开更多
The static and dynamic magnetic controlling characteristics of NiMnGa magnetically controlled shape memory alloy （MSMA） were experimentally studied. The results show that the characteristics of induced strain with r...The static and dynamic magnetic controlling characteristics of NiMnGa magnetically controlled shape memory alloy （MSMA） were experimentally studied. The results show that the characteristics of induced strain with respect to the magnetic field are nonlinear with saturation nature, and dependent on the temperature as well as the load applied to the MSMA. The magnetic shape memory effect can be observed only in complete martensite phase at room temperature. The magnetic permeability of MSMA is not constant and reduces with the increment of magnetic field. The relative saturation magnetic permeability of MSMA is about 1.5.展开更多
Compared with a straight blade, a unique compressor blade integratedforward-swept and positive-curved stacking line is studied experimentally. Aerodynamic parameters ofthe two cascades are measured by a five-hole prob...Compared with a straight blade, a unique compressor blade integratedforward-swept and positive-curved stacking line is studied experimentally. Aerodynamic parameters ofthe two cascades are measured by a five-hole probe at different positions and ink trace flowvisualization is conducted on blade surfaces. The result shows that the swept-curved cascade haslower endwall loss and higher midspan loss as compared with the straight cascade. However, lowerloss is accompanied with lower diffusion factor. Opposite 'C' shape static pressure distribution isestablished on the suction surface of the swept-curved blade, which is helpful for avoiding theaccumulation of low energy fluid in the endwall corner region. Anyhow the studies support theconclusion that the swept-curved blade conduces to not only the reduction of overall loss but alsothe improvement of stable operation in the endwall corner region.展开更多
AIM:To discuss the safety,feasibility and regularity of destruction to porcine spleen in vivo with congestion and tumescence by microwave ablation(MWA).METHODS:Ligation of the splenic vein was used to induce congestio...AIM:To discuss the safety,feasibility and regularity of destruction to porcine spleen in vivo with congestion and tumescence by microwave ablation(MWA).METHODS:Ligation of the splenic vein was used to induce congestion and tumescence in vivo in five porcine spleens,and microwave ablation was performed 2-4 h later.A total of 56 ablation points were ablated and the ablation powers were 30-100 W.The ablation time(1,2,3,4,5,6,7,8,9 and 10 min)was performed at a power of 60 W.After ablation,the ablation size was measured in pigs A,C,D and E and spleen resection.In pig B,the ablation size was measuredand 2 ablation points were sent for pathology analysis and all tissues were sutured following ablation.Pig B was killed 1 wk later and the ablation points were sent for pathology analysis.Bleeding,tissue carbonization surrounding electrodes,and pathological changes were observed,and the effect on destruction volume relative to different ablation powers,times and positions was analyzed.RESULTS:The incidence of bleeding(only small amounts,<20 mL)in the course of ablation was 5.4%(3/56)and was attributed to tissue carbonization surrounding electrodes,which also exhibited an incidence of 5.4%(3/56).The destruction volume was influenced by different ablation powers,times and points.It showed that the ablation lesion size increased with increased ablation time,from 1 to 10 min,when the ablation power was 60 W.Also,the ablation lesion size increased with the increase of ablation power,ranging from 30 to 100 W when the ablation time was set to 3 min.A direct correlation was seen between the destruction volume and ablation time by the power of 60 W(r=0.97542,P<0.0001),and also between the destruction volume and ablation powers at an ablation time of 3 min(r=0.98258,P<0.0001).The destruction volume of zoneⅡ(the extra-2/3 part of the spleen,relative to the fi rst or second class vascular branches),which was near the hilum of the spleen,was noteably larger than the destruction volume of zoneⅠ(the intra-1/3 part of the spleen)which was distal from the hilum of the spleen(P=0.0015).Pathological changes of ablation occurring immediately and 1 wk after MWA showed large areas of coagulation.Immediately following ablation,intact spleen tissues were observed in the areas of coagulation necrosis,mainly around arterioles,and there were no obvious signs of hydropsia and inflammation,while 1 wk following the ablation,the coagulation necrosis was well distributed and complete,as many nuclear fragmentations were detected,and there were obvious signs of hydropsia and inflammation.CONCLUSION:In vivo treatment of congestion and tumescence in the spleen using microwave ablation of water-cooled antenna is a safe and feasible method that is minimally invasive.展开更多
The pulse features of a bubble have a close connection with the boundary condition. When a bubble moves near a rigid wall, it will be attracted by the Bjerknes force of the wall, and a jet pointing at the wall will be...The pulse features of a bubble have a close connection with the boundary condition. When a bubble moves near a rigid wall, it will be attracted by the Bjerknes force of the wall, and a jet pointing at the wall will be generated. In real application, the bubble may move under the combined action of walls in different directions when it forms at the corner of a pipe or at the bottom of a dam. The motion of the bubble shows complex and nonlinear characteristics under these conditions. In order to investigate the bubble pulse features near complex walls, a horizontal wall and a vertical wall are put into the experimental water tank synchronously, and an electric circuit with 200 voltages is designed to generate discharge bubbles, and then experimental study on the bubble pulse features under the combined action of horizontal and vertical walls is carried out. The influences of the combined action of two walls on the bubble shape, pulse period, moving trace and inside jet are obtained by changing the distances from bubble center to the two walls. It aims at providing references for the relevant theoretical and numerical research.展开更多
Aim To design and experimentally study an 80C196KC-based SRD (switched re- luctance motor drive drive sytem) controller,Methods with the guidelines of the digitized SRD system controller,the circuit design and softwar...Aim To design and experimentally study an 80C196KC-based SRD (switched re- luctance motor drive drive sytem) controller,Methods with the guidelines of the digitized SRD system controller,the circuit design and software programming were completed,and a relevantexperimental system was PUT forward to test the newly designed controller.Result The experi-mental study showed that the newlydesigned controller had good speed-adjusting characteristicfor a switched reluctance motor ,its stable error was less than 5% and its full-load startingtime was shorter than 1.8s .Conclusion The new controller has reasonable circuit design and suitable controlling algorithm,and it is a feasible SRD system controller design scheme.展开更多
This study presents a method for measuring the imbalance in a small-sized cylindrical roller.The roller imbalance was calibrated on the built static-pressure-air flotation measurement machine.The impact of the roller ...This study presents a method for measuring the imbalance in a small-sized cylindrical roller.The roller imbalance was calibrated on the built static-pressure-air flotation measurement machine.The impact of the roller imbalance on the dynamic characteristics of a cage were then studied on the aero-bearing test rig.The displacement spectrums with different roller imbalance of the obtained cage orbits under various bearing speed and radial load were used to evaluate the cage stability.The results show that the cage cannot form a stable operating state at a lower bearing speed with or without the unbalanced rollers.The cage with balanced rollers gradually develops stable motion with the increase of the bearing speed.The existence of a small roller imbalance causes the stability of the cage to deteriorate.With an increase in the bearing speed and radial load,the cage with the unbalanced rollers runs unsteadily accompanied by a high-frequency vibration when the roller imbalance is large enough.The vibration amplitude of the cage in the horizontal direction is greater than that in the vertical direction during an unstable operation,which is similar in the stable status.展开更多
Theoretical analysis and field monitoring show that lateral vibration has very important effect on casing wear in deep & ultra-deep well drilling. The wear mechanism of casing under impact-sliding work conditions ...Theoretical analysis and field monitoring show that lateral vibration has very important effect on casing wear in deep & ultra-deep well drilling. The wear mechanism of casing under impact-sliding work conditions has been investigated and many experiments have been completed with a newly developed full-scale casing wear test machine. Test results present that adhesion wear, contact fatigue, and grinding abrasion are the main wear mechanisms under impact-sliding test conditions. The friction coefficient and linear wear rate of the casing rise obviously with an increase in impact load. And the larger the impact load, the rougher the worn surface of the casing. The linear wear rate decreased slightly but the average friction coefficient increased slightly with an increase in impact frequency under an impact load of 2,500 N. Both the linear wear rate of the casing and the average friction coefficient increased substantially with an increase in impact frequency under an impact load of 4,000 N. Under lower impact load conditions, grinding abrasion and contact fatigue are the main mechanisms of casing wear; under higher impact load conditions, adhesion wear and contact fatigue are the main mechanisms of casing wear.展开更多
This paper presented the results of an experimental investigation into the resistance performance of a wave-piercing trimaran with three alternative side hull forms,including asymmetric inboard,asymmetric outboard,and...This paper presented the results of an experimental investigation into the resistance performance of a wave-piercing trimaran with three alternative side hull forms,including asymmetric inboard,asymmetric outboard,and symmetric at various stagger/separation positions.Model tests were carried out at the National Iranian Marine Laboratory(NIMALA)towing tank using a scale model of a trimaran at the Froude numbers from 0.225 to 0.60.Results showed that by moving the side hulls to the forward of the main hull transom,the total resistance coefficient of trimaran decreased.Findings,furthermore,demonstrated that the symmetry shape of the side hull had the best performance on total resistance among three side hull forms.Results of this study are useful for selecting the side hull configuration from the resistance viewpoint.展开更多
An experimental animal model of malignant soft-tissue tumor was established to investigate the applied value of multi-slice spiral CT perfusion imaging preliminarily. Ten New Zealand white rabbits which were implanted...An experimental animal model of malignant soft-tissue tumor was established to investigate the applied value of multi-slice spiral CT perfusion imaging preliminarily. Ten New Zealand white rabbits which were implanted with VX2 tumor in either proximal thigh were subjected to CT plain scan and perfusion scan two weeks later respectively, then the original perfusion images were transmitted to AW4.0 Workstation. The functional maps and perfusion parameters including blood flow （BF）, blood volume （BV）, mean transit time （MTT） and permeability surface （PS） were computed and analyzed. All the values of BF, BV and PS in VX2 soft-tissue tumors were obviously higher while the MTT-values were lower than those in the normal muscular tissues significantly. It was suggested that multi-slice spiral CT perfusion imaging is an accurate, convenient and relatively safe functional imaging technique, and can give a quantitative assessment to angiogenesis and blood perfusion of soft-tissue tumors.展开更多
The variation of stable isotope ratios in natural waters provides valuable information that can be used to trace water movement. Evaporation plays a crucial role in determining the variation of stable isotopes. In thi...The variation of stable isotope ratios in natural waters provides valuable information that can be used to trace water movement. Evaporation plays a crucial role in determining the variation of stable isotopes. In this paper, several evaporation experiments were conducted in order to study the stable isotopic fractionation mechanism of water and analyze the influence of different temperatures on evaporation fractionation. Three group experiments of water evaporation under different temperatures and initial isotopic values were carried out. The results show that fractionation factors of hydrogen and oxygen may increase with temperature, and the average enrichment degree of hydrogen isotope D is 3.432 times that of oxygen isotope 18O. The results also show that the isotopic composition of the initial water has little influence on water evaporation fractionation, which is mainly affected by the state variables in the evaporation process, such as temperature. This research provides experimental data for further understanding the evaporation fractionation mechanism.展开更多
Bonding fiber reinforced polymer （FRP） has been commonly used to improve the seismic behavior of circular reinforced concrete （RC） columns in engineering practice. However, FRP jackets have a significant stress hy...Bonding fiber reinforced polymer （FRP） has been commonly used to improve the seismic behavior of circular reinforced concrete （RC） columns in engineering practice. However, FRP jackets have a significant stress hysteresis effect in this strengthening method, and pre-tensioning the FRP can overcome this problem. This paper presents test results of 25 circular RC columns strengthened with pre-stressed FRP strips under low cyclic loading. The pre-stressing of the FRP strips, types of FRP strips and longitudinal reinforcement, axial load ratio, pre-damage degree and surface treatments of the specimens are considered as the primary factors in the tests. According to the failure modes and hysteresis curves of the specimens, these factors are analyzed to investigate their effect on bearing capacity, ductility, hysteretic behavior, energy dissipation capacity and other important seismic behaviors. The results show that the initial lateral confined stress provided by pre-stressed FRP strips can effectively inhibit the emergence and development of diagonal shear cracks, and change the failure modes of specimens from brittle shear failure to bending or bending-shear failure with better ductility. As a result, the bearing capacity, ductility, energy dissipation capacity and deformation capacity of the strengthened specimens are all significantly improved.展开更多
基金supported by the Hundred Talents Programof the Chinese Academy of Sciences,the Pre-Research Project JZX7Y20220414101801the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB35000000)the National Natural Science Foundation Projects(No.51806231).
文摘Helium sorption cooler technology is a key means to realize highly reliable low-vibration very lowtemperature environments,which have important applications in fields such as quantum computing and space exploration.The laboratory designed a superfluid suppression small hole and a multi-ribbed condenser,developed a reliable-performance helium sorption cooler(HSC),and conducted experimental studies.Experimental results show that the prototype can achieve the lowest cooling temperature of 873 mK without load by filling 6MPa helium at room temperature.The low-temperature hold time is 26 h,and the temperature fluctuation is within 0.8 mK.The cooling power of the helium sorption cooler is 1 mW@0.98 K@3.5 h.Experimental results indicate that when the charging pressure is reduced to 4MPa,theminimum temperature decreases to 836mK,and the hold time shortens to 16 h.When the pre-cooling temperature increases from 3.9 to 4.9 K,the hold time is reduced to 3 h.
文摘Ultrahigh-performance concrete(UHPC)is a groundbreaking kind of concrete that distinguishes itself from conventional concrete through its unique material properties.Understanding and managing the time-dependent characteristics of these materials is essential for their effective use in various construction applications.This study presents an experimental evaluation of the compressive and bending properties of the UHPC incorporating polypropylene,steel,and glass fibers.Based on ACI-211 guidelines,the UHPC mix was designed by using three types of aggregates:limestone,andesite,and quartzite,along with 5%fiber content(at varying percentages of 0,5%,10%,15%,and 20%)relative to the cementitious materials,and three different water-to-cement(w/c)ratios(0.24,0.3,and 0.4)were used.In this research,the compressive and flexural strength tests were conducted.The results show that increasing the values of the fibers significantly enhances the compressive strength of the studied samples.Furthermore,the utilization of fibers markedly improves the bending strength of the samples,demonstrating a strong correlation with the yield resistance of the material.Also,findings show that using steel fibers increases the compressive and bending strength of the tested samples more than polypropylene and glass fibers.For instance,in UHPC samples with 0.4 w/c,the average compressive strength values are 82.2 MPa,70.3 MPa,and 67.1 MPa for steel,polypropylene,and glass fibers,respectively.Also,in the flexural strength test,the modulus of rupture is obtained as an average of 6.24 MPa,5.24 MPa and 4.83 MPa for UHPC samples with steel,polypropylene and glass fibers,respectively.
文摘BACKGROUND IgE plays a critical role in allergic inflammation and asthma pathogenesis.This study investigates the involvement of IgE cells in asthma exacerbation and evaluates the effectiveness of targeted interventions.AIM To evaluate the role of IgE in the exacerbation of allergic asthma and to determine the clinical efficacy of anti-IgE therapy in improving disease outcomes.Specifically,the study investigates changes in serum IgE levels,lung function,asthma control scores,and the frequency of acute exacerbations among patients receiving standard therapy with or without anti-IgE intervention.METHODS A total of 200 patients diagnosed with moderate to severe asthma were enrolled in this experimental study conducted from April 2024 to April 2025.Participants were randomized to receive either standard asthma therapy or therapy combined with anti-IgE agents.IgE levels and asthma control parameters were monitored.RESULTS Participants receiving anti-IgE treatment demonstrated a significant reduction in serum IgE levels(P<0.001),improved Forced expiratory volume in one second scores,and fewer exacerbation episodes compared to the control group.CONCLUSION IgE cells significantly contribute to asthma severity,and targeted therapy against IgE can improve disease outcomes.These findings underscore the importance of immunomodulatory strategies in asthma management.
基金supported by grants from National High-Level Hospital Clinical Research Funding(2023-GSP-RC-04).
文摘This study aimed to evaluate the feasibility,safety,and efficacy of a noveltranscatheter suture closure system(HaloStitch^(®))for patent foramen ovale(PFO)closure in a swine model.Methods:Thirteen swine underwentexperimental PF0 model creation.All animals received implantationof the transcatheter suture closure system to evaluate procedural success.Comprehensive follow-up over sixmonths included serial ultrasound imaging,histopathological analysis,and gross anatomical exaninationof cardiac specimens.Results:Successful HaloStitch^(®)device implantation was adhieved in 11 of 13 swine.Gross anatomical examination confirrned secure positioning of all sutures in the atrial septum,with noredundancy or thrombus formation.Postoperative ultrasound demonstrated stable suture and staplepositions throughout follow-up,with no evidence of suture breakage,displacement,or thrombus.Stapleswere clearly visualized under ultrasound imaging,Both the atrial septal defect orifice diameter and residualseptal shunt flow velocity decreased significantly during the observation period.Histopathological analysisrevealed partially organized thrombi at the implant head and fibrous connective tissue encapsulation withlocalized inflammatory cell infiltration surrounding the polymer material.Conclsions:The transcathetersuture closure system(HaloStitch^(®))demonstrated feasibility,safety,and biocompatib ility for PFO closure ina swine model,supporting its potential for clinical translation.
文摘In this paper,experimental and numerical studies of heat transfer in a test local of side H=0.8 m heated from below are presented and compared.All the walls,the rest of the floor and the ceiling are made from plywood and polystyrene in sandwich form(3 mmplywood-3 cm polystyrene-3 mmplywood)just on one of the vertical walls contained a glazed door(2 H/3×0.15 m).This local is heated during two heating cycles by a square plate of iron the width L=0.6 H,which represents the heat source,its temperature T_(h) is controlled.The plate is heated for two cycles by an adjustable set-point heat source placed just down the center of it.For each cycle,the heat source is switched“on”for 6 h and switched“off”for 6 h.The outdoor air temperature is kept constant at a low temperature T_(c)<T_(h).All measurements are carried out with k-type thermocouples and with flux meters.Results will be qualitatively presented for two cycles of heating in terms of temperatures and heat flux densitiesϕfor various positions of the test local.The temperature evolution of the center and the profile of the temperature along the vertical centerline are compared by two dimensions simulation using the lattice Boltzmann method.The comparison shows a good agreement with a difference that does not exceed±1℃.
基金Supported by National Key Research and Development Program of China (Grant No.2021YFF0600208)National Natural Science Foundation of China (Grant No.52005170)Hunan Provincial Science and Technology Innovation Program of China (Grant No.2020RC4018)。
文摘Low damping characteristics have always been a key sticking points in the development of gas bearings.The application of squeeze film dampers can significantly improve the damping performance of gas lubricated bearings.This paper proposed a novel hermetic diaphragm squeeze film damper(HDSFD)for oil-free turbomachinery supported by gas lubricated bearings.Several types of HDSFDs with symmetrical structure were proposed for good damping performance.By considering the compressibility of the damper fluid,based on hydraulic fluid mechanics theory,a dynamic model of HDSFDs under medium is proposed,which successfully reflects the frequency dependence of force coefficients.Based on the dynamic model,the effects of damper fluid viscosity,bulk modulus of damper fluid,thickness of damper fluid film and plunger thickness on the dynamic stiffness and damping of HDSFDs were analyzed.An experimental test rig was assembled and series of experimental studies on HDSFDs were conducted.The damper fluid transverse flow is added to the existing HDSFD concept,which aims to make the dynamic force coefficients independent of frequency.Although the force coefficient is still frequency dependent,the damping coefficient at high frequency excitation with damper fluid supply twice as that without damper fluid supply.The results serve as a benchmark for the calibration of analytical tools under development.
文摘Experimental study on the fundamental behavior of box shape steel reinforced concrete （SRC） beams was conducted. Seven 1 ： 3 scale model SRC beams were tested to failure. The experimental results indicate that the flexural strength increases with the increase of the ratio of flexural reinforcement and the thickness of flange of the shape steel; the shear strength increases with the increase in the thickness of the web of the shape steel. Concrete filled in the box shape steel can prevent the early failure of specimens due to the buckling of the box shape steel, and increase the ultimate load. Measures should be made to strengthen the connection and co-work between the shape steel and the concrete. Formulae for flexural and shear strength of the composite beams are proposed, and the calculated results are in good agreement with the experimental results. In general, the box shape SRC beam is a kind of ductile member, and it is suitable for extensive engineering application.
基金supported by the National Natural Science Foundation of China(Grant No.50905187)the Shandong Provincial Natural Science Foundation(Grant No.ZR2009FQ001)
文摘This article studies the application of the alternating current field measurement （ACFM） method in defect detection for underwater structures. Numerical model of the ACFM system is built for structure surface defect detection in seawater environment. Finite element simulation is performed to investigate rules and characteristics of the electromagnetic signal distribution in the defected area. In respect of the simulation results, underwater artificial crack detection experiments are designed and conducted for the ACFM system. The experiment results show that the ACFM system can detect cracks in underwater structures and the detection accuracy is higher than 85%. This can meet the engineering requirement of underwater structure defect detection. The results in this article can be applied to establish technical foundation for the optimization and development of ACFM based underwater structure defects detection system.
文摘A new technique was introduced for sand stabilization and re-vegetation by use of lignin sand stabilizing material(LSSM). LSSM is a reconstructed organic compound with lignin as the most dominant component from the extracts of black-liquor issued by straw pulp paper mills. Unlike the polyvinyl acetate or foamed asphalt commonly used for dune stabilization, the new material is plant-friendly and can be used with virescence actions simultaneously. The field experimental study was conducted since 2001 in China's Northwest Ningxia Hui Autonomous Region and has been proved that LSSM is effective in stabilizing the fugitive dunes, making the arenaceous plants survive and the bare dune vegetative. The advisable solution concentration is 2% and the optimal field spraying quantity is 2 5 L/m^2 The soil nutrients of the stabilized and greened dune, such as organic matter, available phosphorous and total nitrogen are all increased compared with the control treatment, which is certainly helpful to the growth of arenaceous plants. The technique is worthwhile to be popularized because it is provided not only a new method for desertification control but also an outlet for cleaning contaminants issued from the straw paper mills.
基金This work was supported by the National Natural Science Foundation of China under grant No.50177019by the Education Department of China under grant No.20040142004.
文摘The static and dynamic magnetic controlling characteristics of NiMnGa magnetically controlled shape memory alloy （MSMA） were experimentally studied. The results show that the characteristics of induced strain with respect to the magnetic field are nonlinear with saturation nature, and dependent on the temperature as well as the load applied to the MSMA. The magnetic shape memory effect can be observed only in complete martensite phase at room temperature. The magnetic permeability of MSMA is not constant and reduces with the increment of magnetic field. The relative saturation magnetic permeability of MSMA is about 1.5.
文摘Compared with a straight blade, a unique compressor blade integratedforward-swept and positive-curved stacking line is studied experimentally. Aerodynamic parameters ofthe two cascades are measured by a five-hole probe at different positions and ink trace flowvisualization is conducted on blade surfaces. The result shows that the swept-curved cascade haslower endwall loss and higher midspan loss as compared with the straight cascade. However, lowerloss is accompanied with lower diffusion factor. Opposite 'C' shape static pressure distribution isestablished on the suction surface of the swept-curved blade, which is helpful for avoiding theaccumulation of low energy fluid in the endwall corner region. Anyhow the studies support theconclusion that the swept-curved blade conduces to not only the reduction of overall loss but alsothe improvement of stable operation in the endwall corner region.
基金Supported by Guangdong Provincial Science and Technology FundGuangdong Provincial Scientifi c Project Grant
文摘AIM:To discuss the safety,feasibility and regularity of destruction to porcine spleen in vivo with congestion and tumescence by microwave ablation(MWA).METHODS:Ligation of the splenic vein was used to induce congestion and tumescence in vivo in five porcine spleens,and microwave ablation was performed 2-4 h later.A total of 56 ablation points were ablated and the ablation powers were 30-100 W.The ablation time(1,2,3,4,5,6,7,8,9 and 10 min)was performed at a power of 60 W.After ablation,the ablation size was measured in pigs A,C,D and E and spleen resection.In pig B,the ablation size was measuredand 2 ablation points were sent for pathology analysis and all tissues were sutured following ablation.Pig B was killed 1 wk later and the ablation points were sent for pathology analysis.Bleeding,tissue carbonization surrounding electrodes,and pathological changes were observed,and the effect on destruction volume relative to different ablation powers,times and positions was analyzed.RESULTS:The incidence of bleeding(only small amounts,<20 mL)in the course of ablation was 5.4%(3/56)and was attributed to tissue carbonization surrounding electrodes,which also exhibited an incidence of 5.4%(3/56).The destruction volume was influenced by different ablation powers,times and points.It showed that the ablation lesion size increased with increased ablation time,from 1 to 10 min,when the ablation power was 60 W.Also,the ablation lesion size increased with the increase of ablation power,ranging from 30 to 100 W when the ablation time was set to 3 min.A direct correlation was seen between the destruction volume and ablation time by the power of 60 W(r=0.97542,P<0.0001),and also between the destruction volume and ablation powers at an ablation time of 3 min(r=0.98258,P<0.0001).The destruction volume of zoneⅡ(the extra-2/3 part of the spleen,relative to the fi rst or second class vascular branches),which was near the hilum of the spleen,was noteably larger than the destruction volume of zoneⅠ(the intra-1/3 part of the spleen)which was distal from the hilum of the spleen(P=0.0015).Pathological changes of ablation occurring immediately and 1 wk after MWA showed large areas of coagulation.Immediately following ablation,intact spleen tissues were observed in the areas of coagulation necrosis,mainly around arterioles,and there were no obvious signs of hydropsia and inflammation,while 1 wk following the ablation,the coagulation necrosis was well distributed and complete,as many nuclear fragmentations were detected,and there were obvious signs of hydropsia and inflammation.CONCLUSION:In vivo treatment of congestion and tumescence in the spleen using microwave ablation of water-cooled antenna is a safe and feasible method that is minimally invasive.
基金financially supported by the China National Funds for Distinguished Young Scholars(Grant No.51222904)the National Natural Science Foundation of China(Grant No.51379039)
文摘The pulse features of a bubble have a close connection with the boundary condition. When a bubble moves near a rigid wall, it will be attracted by the Bjerknes force of the wall, and a jet pointing at the wall will be generated. In real application, the bubble may move under the combined action of walls in different directions when it forms at the corner of a pipe or at the bottom of a dam. The motion of the bubble shows complex and nonlinear characteristics under these conditions. In order to investigate the bubble pulse features near complex walls, a horizontal wall and a vertical wall are put into the experimental water tank synchronously, and an electric circuit with 200 voltages is designed to generate discharge bubbles, and then experimental study on the bubble pulse features under the combined action of horizontal and vertical walls is carried out. The influences of the combined action of two walls on the bubble shape, pulse period, moving trace and inside jet are obtained by changing the distances from bubble center to the two walls. It aims at providing references for the relevant theoretical and numerical research.
文摘Aim To design and experimentally study an 80C196KC-based SRD (switched re- luctance motor drive drive sytem) controller,Methods with the guidelines of the digitized SRD system controller,the circuit design and software programming were completed,and a relevantexperimental system was PUT forward to test the newly designed controller.Result The experi-mental study showed that the newlydesigned controller had good speed-adjusting characteristicfor a switched reluctance motor ,its stable error was less than 5% and its full-load startingtime was shorter than 1.8s .Conclusion The new controller has reasonable circuit design and suitable controlling algorithm,and it is a feasible SRD system controller design scheme.
基金supported by the National Science Foundation for Young Scientists of China(No.51905152)。
文摘This study presents a method for measuring the imbalance in a small-sized cylindrical roller.The roller imbalance was calibrated on the built static-pressure-air flotation measurement machine.The impact of the roller imbalance on the dynamic characteristics of a cage were then studied on the aero-bearing test rig.The displacement spectrums with different roller imbalance of the obtained cage orbits under various bearing speed and radial load were used to evaluate the cage stability.The results show that the cage cannot form a stable operating state at a lower bearing speed with or without the unbalanced rollers.The cage with balanced rollers gradually develops stable motion with the increase of the bearing speed.The existence of a small roller imbalance causes the stability of the cage to deteriorate.With an increase in the bearing speed and radial load,the cage with the unbalanced rollers runs unsteadily accompanied by a high-frequency vibration when the roller imbalance is large enough.The vibration amplitude of the cage in the horizontal direction is greater than that in the vertical direction during an unstable operation,which is similar in the stable status.
基金supported by the National Natural Science Foundation of China (No.50475037)
文摘Theoretical analysis and field monitoring show that lateral vibration has very important effect on casing wear in deep & ultra-deep well drilling. The wear mechanism of casing under impact-sliding work conditions has been investigated and many experiments have been completed with a newly developed full-scale casing wear test machine. Test results present that adhesion wear, contact fatigue, and grinding abrasion are the main wear mechanisms under impact-sliding test conditions. The friction coefficient and linear wear rate of the casing rise obviously with an increase in impact load. And the larger the impact load, the rougher the worn surface of the casing. The linear wear rate decreased slightly but the average friction coefficient increased slightly with an increase in impact frequency under an impact load of 2,500 N. Both the linear wear rate of the casing and the average friction coefficient increased substantially with an increase in impact frequency under an impact load of 4,000 N. Under lower impact load conditions, grinding abrasion and contact fatigue are the main mechanisms of casing wear; under higher impact load conditions, adhesion wear and contact fatigue are the main mechanisms of casing wear.
文摘This paper presented the results of an experimental investigation into the resistance performance of a wave-piercing trimaran with three alternative side hull forms,including asymmetric inboard,asymmetric outboard,and symmetric at various stagger/separation positions.Model tests were carried out at the National Iranian Marine Laboratory(NIMALA)towing tank using a scale model of a trimaran at the Froude numbers from 0.225 to 0.60.Results showed that by moving the side hulls to the forward of the main hull transom,the total resistance coefficient of trimaran decreased.Findings,furthermore,demonstrated that the symmetry shape of the side hull had the best performance on total resistance among three side hull forms.Results of this study are useful for selecting the side hull configuration from the resistance viewpoint.
文摘An experimental animal model of malignant soft-tissue tumor was established to investigate the applied value of multi-slice spiral CT perfusion imaging preliminarily. Ten New Zealand white rabbits which were implanted with VX2 tumor in either proximal thigh were subjected to CT plain scan and perfusion scan two weeks later respectively, then the original perfusion images were transmitted to AW4.0 Workstation. The functional maps and perfusion parameters including blood flow （BF）, blood volume （BV）, mean transit time （MTT） and permeability surface （PS） were computed and analyzed. All the values of BF, BV and PS in VX2 soft-tissue tumors were obviously higher while the MTT-values were lower than those in the normal muscular tissues significantly. It was suggested that multi-slice spiral CT perfusion imaging is an accurate, convenient and relatively safe functional imaging technique, and can give a quantitative assessment to angiogenesis and blood perfusion of soft-tissue tumors.
基金supported by the National Natural Science Foundation of China (Grant No. 50679024)the Innovation Program for College Graduate of Jiangsu Province of 2007 (Grant No. CX07B_130Z)
文摘The variation of stable isotope ratios in natural waters provides valuable information that can be used to trace water movement. Evaporation plays a crucial role in determining the variation of stable isotopes. In this paper, several evaporation experiments were conducted in order to study the stable isotopic fractionation mechanism of water and analyze the influence of different temperatures on evaporation fractionation. Three group experiments of water evaporation under different temperatures and initial isotopic values were carried out. The results show that fractionation factors of hydrogen and oxygen may increase with temperature, and the average enrichment degree of hydrogen isotope D is 3.432 times that of oxygen isotope 18O. The results also show that the isotopic composition of the initial water has little influence on water evaporation fractionation, which is mainly affected by the state variables in the evaporation process, such as temperature. This research provides experimental data for further understanding the evaporation fractionation mechanism.
基金National Natural Science Foundation of China under Grant No.51178029 State Key Laboratory for Disaster Reduction in Civil Engineering at Tongji University under Grant No.SLDRCE08-MB-01
文摘Bonding fiber reinforced polymer （FRP） has been commonly used to improve the seismic behavior of circular reinforced concrete （RC） columns in engineering practice. However, FRP jackets have a significant stress hysteresis effect in this strengthening method, and pre-tensioning the FRP can overcome this problem. This paper presents test results of 25 circular RC columns strengthened with pre-stressed FRP strips under low cyclic loading. The pre-stressing of the FRP strips, types of FRP strips and longitudinal reinforcement, axial load ratio, pre-damage degree and surface treatments of the specimens are considered as the primary factors in the tests. According to the failure modes and hysteresis curves of the specimens, these factors are analyzed to investigate their effect on bearing capacity, ductility, hysteretic behavior, energy dissipation capacity and other important seismic behaviors. The results show that the initial lateral confined stress provided by pre-stressed FRP strips can effectively inhibit the emergence and development of diagonal shear cracks, and change the failure modes of specimens from brittle shear failure to bending or bending-shear failure with better ductility. As a result, the bearing capacity, ductility, energy dissipation capacity and deformation capacity of the strengthened specimens are all significantly improved.
