Firstly, the Earth＇s gravitational field from the past Challenging Minisatellite Payload （CHAMP） mission is determined using the energy conservation principle, the combined error model of the cumulative geoid heigh...Firstly, the Earth＇s gravitational field from the past Challenging Minisatellite Payload （CHAMP） mission is determined using the energy conservation principle, the combined error model of the cumulative geoid height influenced by three instrument errors from the current Gravity Recovery and Climate Experiment （GRACE） and future GRACE Follow-On missions is established based on the semi-analytical method, and the Earth＇s gravitational field from the executed Gravity Field and Steady-State Ocean Circulation Explorer （GOCE） mission is recovered by the space-time-wise approach. Secondly, the cumulative geoid height errors are 1.727 × 10^-1 m, 1.839 × 10^-1 m and 9.025 × 10^ -2 m at degrees 70,120 and 250 from the implemented three-stage satellite gravity missions consisting of CHAMP, GRACE and GOCE, which preferably accord with those from the existing earth gravity field models involving EIGEN-CHAMP03S, EICEN-GRACE02S and GO_CONS GCF 2 DIR R1. The cumulative geoid height error is 6.847 × 10 ^-2 m at degree 250 from the future GRACE Follow-On mission. Finally, the complementarity among the four-stage satellite gravity missions including CHAMP, GRACE, GOCE and GRACE Follow-On is demonstrated contrastively.展开更多
Objective Diabetes remission has emerged as an achievable treatment goal,shifting the focus of care from increasing medication use to restoring metabolic health.While clinical trials show that remission is possible in...Objective Diabetes remission has emerged as an achievable treatment goal,shifting the focus of care from increasing medication use to restoring metabolic health.While clinical trials show that remission is possible in controlled settings,evidence remains limited regarding its implementation in routine care within middle-income,rice-based dietary contexts.This study aims to explore healthcare provider experiences with implementing diabetes remission services in Thailand,focusing on dietary strategies,deprescription practices and patient management in routine care settings.Design Qualitative study using semi-structured,in-depth interviews,supplemented by structured questionnaires and programme documents.Setting Thirteen healthcare facilities across six Thai regions and two national-level professional or policy organisations.Participants 17 key informants purposively sampled for regional,institutional and professional diversity,including physicians,nurses,dietitians and national programme leaders.Data were collected and analysed iteratively until no new insights emerged.Thematic content analysis was conducted in QDA Miner Lite v3.0 with investigator triangulation.Result Five major themes emerged:key strengths,success factors,nutritional approaches and lifestyle modification,implementation challenges,and development strategies.Multidisciplinary teamwork,personalised care plans and regular monitoring facilitated service delivery.Culturally adapted dietary strategies,such as low-carbohydrate Thai-style meals and intermittent fasting,were widely used.Challenges included unclear clinical guidelines,limited staffing and technological disparities.Medication deprescription varied across sites due to the absence of standardised protocols.Healthcare providers emphasised the need for community engagement and policy support to enable scale-up.Real-world implementation of diabetes remission services is feasible but challenged by systemic constraints and contextual variability.Flexible,culturally tailored approaches,empowered care teams and supportive policy frameworks are essential for sustainability.展开更多
基金supported by the Main Direction Program of Knowledge Innovation of Chinese Academy of Sciences for Distinguished Young Scholar(KZCX2-EW-QN114)the National Natural Science Foundation of China(41004006,41131067,11173049 and 41274041)+7 种基金the Merit-based Scientific Research Foundation of the State Ministry of Human Resources and Social Security of China for Returned Overseas Chinese Scholars(Z01101)the Open Research Fund Program of the Key Laboratory of Geospace Environment and Geodesy,Ministry of Education,China(11-01-02)the Open Research Fund Program of the Key Laboratory of Geo-Informatics of National Administration of Surveying,Mapping and Geoinformation of China(201322)the Open Research Fund Program of the State Key Laboratory of Geoinformation Engineering,China(SKLGIE2013-M-1-5)the Main Direction Program of Institute of Geodesy and Geophysics,Chinese Academy of Sciences(Y309451045)the Research Fund Program of State Key Laboratory of Geodesy and Earth's Dynamics,China(Y309491050)the Research Fund of the National Civilian Space Infrastructure Project(Y419341034)the Research Fund of the Lu Jiaxi Young Talent and the Youth Innovation Promotion Association of Chinese Academy of Science(Y305171017)
文摘Firstly, the Earth＇s gravitational field from the past Challenging Minisatellite Payload （CHAMP） mission is determined using the energy conservation principle, the combined error model of the cumulative geoid height influenced by three instrument errors from the current Gravity Recovery and Climate Experiment （GRACE） and future GRACE Follow-On missions is established based on the semi-analytical method, and the Earth＇s gravitational field from the executed Gravity Field and Steady-State Ocean Circulation Explorer （GOCE） mission is recovered by the space-time-wise approach. Secondly, the cumulative geoid height errors are 1.727 × 10^-1 m, 1.839 × 10^-1 m and 9.025 × 10^ -2 m at degrees 70,120 and 250 from the implemented three-stage satellite gravity missions consisting of CHAMP, GRACE and GOCE, which preferably accord with those from the existing earth gravity field models involving EIGEN-CHAMP03S, EICEN-GRACE02S and GO_CONS GCF 2 DIR R1. The cumulative geoid height error is 6.847 × 10 ^-2 m at degree 250 from the future GRACE Follow-On mission. Finally, the complementarity among the four-stage satellite gravity missions including CHAMP, GRACE, GOCE and GRACE Follow-On is demonstrated contrastively.
文摘Objective Diabetes remission has emerged as an achievable treatment goal,shifting the focus of care from increasing medication use to restoring metabolic health.While clinical trials show that remission is possible in controlled settings,evidence remains limited regarding its implementation in routine care within middle-income,rice-based dietary contexts.This study aims to explore healthcare provider experiences with implementing diabetes remission services in Thailand,focusing on dietary strategies,deprescription practices and patient management in routine care settings.Design Qualitative study using semi-structured,in-depth interviews,supplemented by structured questionnaires and programme documents.Setting Thirteen healthcare facilities across six Thai regions and two national-level professional or policy organisations.Participants 17 key informants purposively sampled for regional,institutional and professional diversity,including physicians,nurses,dietitians and national programme leaders.Data were collected and analysed iteratively until no new insights emerged.Thematic content analysis was conducted in QDA Miner Lite v3.0 with investigator triangulation.Result Five major themes emerged:key strengths,success factors,nutritional approaches and lifestyle modification,implementation challenges,and development strategies.Multidisciplinary teamwork,personalised care plans and regular monitoring facilitated service delivery.Culturally adapted dietary strategies,such as low-carbohydrate Thai-style meals and intermittent fasting,were widely used.Challenges included unclear clinical guidelines,limited staffing and technological disparities.Medication deprescription varied across sites due to the absence of standardised protocols.Healthcare providers emphasised the need for community engagement and policy support to enable scale-up.Real-world implementation of diabetes remission services is feasible but challenged by systemic constraints and contextual variability.Flexible,culturally tailored approaches,empowered care teams and supportive policy frameworks are essential for sustainability.
