Cardiovascular diseases(CVD)and their risk factors are exerting an increasingly significant impact on public health,and the incidence rate of CVD continues to rise.This article provides an interpretation of essentials...Cardiovascular diseases(CVD)and their risk factors are exerting an increasingly significant impact on public health,and the incidence rate of CVD continues to rise.This article provides an interpretation of essentials from the newly published Annual Report on Cardiovascular Health and Diseases in China(2024),aiming to offer scientific evidence for CVD prevention,treatment,and the formulation of relevant policies.展开更多
IN the Shanghai Jewish Refugees Museum,a beautiful handbag is waiting for its owner in a display cabinet.The handbag belongs to a Jewish couple.When they sought refuge in Shanghai during World War II,they pawned the h...IN the Shanghai Jewish Refugees Museum,a beautiful handbag is waiting for its owner in a display cabinet.The handbag belongs to a Jewish couple.When they sought refuge in Shanghai during World War II,they pawned the handbag to Jin Wenzhen’s grandfather in exchange for their child’s medical expenses.He lent the couple the cash equivalent of one month’s revenue from his rice shop,but then never saw them again.展开更多
In recent years,surrogate models derived from genuine data samples have proven to be efficient in addressing optimization challenges that are costly or time⁃intensive.However,the individuals in the population become i...In recent years,surrogate models derived from genuine data samples have proven to be efficient in addressing optimization challenges that are costly or time⁃intensive.However,the individuals in the population become indistinguishable as the curse of dimensionality increases in the objective space and the accumulation of surrogate approximated errors.Therefore,in this paper,each objective function is modeled using a radial basis function approach,and the optimal solution set of the surrogate model is located by the multi⁃objective evolutionary algorithm of strengthened dominance relation.The original objective function values of the true evaluations are converted to two indicator values,and then the surrogate models are set up for the two performance indicators.Finally,an adaptive infill sampling strategy that relies on approximate performance indicators is proposed to assist in selecting individuals for real evaluations from the potential optimal solution set.The algorithm is contrasted against several advanced surrogate⁃assisted evolutionary algorithms on two suites of test cases,and the experimental findings prove that the approach is competitive in solving expensive many⁃objective optimization problems.展开更多
沿革为了刺激技术创新,美国很早就制定颁布了相应的税收优惠制度。1954年美国《国内税收法典》就确立了研发费用扣除制度(174节)。但是令人遗憾的是,研发费用扣除制度没有带来预想的效果。数据显示,研发投资与国民生产总值的比例从1968...沿革为了刺激技术创新,美国很早就制定颁布了相应的税收优惠制度。1954年美国《国内税收法典》就确立了研发费用扣除制度(174节)。但是令人遗憾的是,研发费用扣除制度没有带来预想的效果。数据显示,研发投资与国民生产总值的比例从1968年的2.01%下降到1975年的1.58%。更重要的是,美国将其大部分研发投资都用于国防工业。与其他发达国家相比,它的非国防研发支出(civilian research expense)是比较少的。1970-1980年间,美国的研发投入与GDP的比例始终在1.5%到2%之间徘徊。而在同时段的德国和日本,这一比例从来没有低过1.9%。展开更多
英汉语均广泛使用比较级,但英语用比较级更广泛些,花样也多些。因此,相对说来,英译汉困难多些。其实汉译英也不易,只是一般采用平铺直叙的译法,不常采用英语丰富多采的表达方式来翻译。例如下面提到的“绝不坏”,一般就译为“not bat at...英汉语均广泛使用比较级,但英语用比较级更广泛些,花样也多些。因此,相对说来,英译汉困难多些。其实汉译英也不易,只是一般采用平铺直叙的译法,不常采用英语丰富多采的表达方式来翻译。例如下面提到的“绝不坏”,一般就译为“not bat at all”,“not absolutely bad”或“quite good”,很少译为“no less good”。又如“这种布由于很漂亮,也就不算贵了”,一般直译为“This展开更多
有报道称,中国财富性别差距日益扩大,女性不仅被＂剩下＂,而且被＂无视＂。
Shang Wen,a single 32-year-old,a three-year-old’s mother,is a rarity1in China,mainly because her parents helped her purchase her own house in 20...有报道称,中国财富性别差距日益扩大,女性不仅被＂剩下＂,而且被＂无视＂。
Shang Wen,a single 32-year-old,a three-year-old’s mother,is a rarity1in China,mainly because her parents helped her purchase her own house in 2004.＂Property was not too expensive then,and my parents had no idea that the market would take off2,＂says Shang.Little did she know that this investment could end up paying off years later,展开更多
目的评价药品集中带量采购对糖尿病患者住院总费用及各类构成费用的影响。方法基于研究医院的9852份糖尿病患者病案首页数据,整理患者基本信息、医疗服务利用信息及各项医疗费用信息,综合运用普通最小二乘法(ordinary least square,OLS...目的评价药品集中带量采购对糖尿病患者住院总费用及各类构成费用的影响。方法基于研究医院的9852份糖尿病患者病案首页数据,整理患者基本信息、医疗服务利用信息及各项医疗费用信息,综合运用普通最小二乘法(ordinary least square,OLS)和倾向性得分匹配法(propensity score matching,PSM)进行数据分析。结果集中带量采购政策确实能够降低糖尿病住院患者的药品费用(t=-2.27,P<0.05),但是对住院总费用、医疗服务性费用影响不显著。OLS回归低估了药品集中带量采购对患者检查化验耗材费用的增费效应(t=2.26,P<0.05)。结论在进一步加强宣传教育的同时,要有序扩大药品集中带量采购,系统推动医药领域集约式改革,持续放大改革红利,实现患者总体医疗负担减轻,让政策福利遍及更多患者。展开更多
Modern engineering design optimization often relies on computer simulations to evaluate candidate designs, a setup which results in expensive black-box optimization problems. Such problems introduce unique challenges,...Modern engineering design optimization often relies on computer simulations to evaluate candidate designs, a setup which results in expensive black-box optimization problems. Such problems introduce unique challenges, which has motivated the application of metamodel-assisted computational intelligence algorithms to solve them. Such algorithms combine a computational intelligence optimizer which employs a population of candidate solutions, with a metamodel which is a computationally cheaper approximation of the expensive computer simulation. However, although a variety of metamodels and optimizers have been proposed, the optimal types to employ are problem dependant. Therefore, a priori prescribing the type of metamodel and optimizer to be used may degrade its effectiveness. Leveraging on this issue, this study proposes a new computational intelligence algorithm which autonomously adapts the type of the metamodel and optimizer during the search by selecting the most suitable types out of a family of candidates at each stage. Performance analysis using a set of test functions demonstrates the effectiveness of the proposed algorithm, and highlights the merit of the proposed adaptation approach.展开更多
This study presents an autoencoder-embedded optimization(AEO)algorithm which involves a bi-population cooperative strategy for medium-scale expensive problems(MEPs).A huge search space can be compressed to an informat...This study presents an autoencoder-embedded optimization(AEO)algorithm which involves a bi-population cooperative strategy for medium-scale expensive problems(MEPs).A huge search space can be compressed to an informative lowdimensional space by using an autoencoder as a dimension reduction tool.The search operation conducted in this low space facilitates the population with fast convergence towards the optima.To strike the balance between exploration and exploitation during optimization,two phases of a tailored teaching-learning-based optimization(TTLBO)are adopted to coevolve solutions in a distributed fashion,wherein one is assisted by an autoencoder and the other undergoes a regular evolutionary process.Also,a dynamic size adjustment scheme according to problem dimension and evolutionary progress is proposed to promote information exchange between these two phases and accelerate evolutionary convergence speed.The proposed algorithm is validated by testing benchmark functions with dimensions varying from 50 to 200.As indicated in our experiments,TTLBO is suitable for dealing with medium-scale problems and thus incorporated into the AEO framework as a base optimizer.Compared with the state-of-the-art algorithms for MEPs,AEO shows extraordinarily high efficiency for these challenging problems,t hus opening new directions for various evolutionary algorithms under AEO to tackle MEPs and greatly advancing the field of medium-scale computationally expensive optimization.展开更多
Along with the development of society and the rapid economic growth in the past decades, hypertension and other chronic diseases have become important reasons for people＇s poverty caused by illness in China. This stu...Along with the development of society and the rapid economic growth in the past decades, hypertension and other chronic diseases have become important reasons for people＇s poverty caused by illness in China. This study collected a total of 5857 people from 2010 to 2013 randomly from the database of the Medical Insurance Department （MID）, including 3229 people in Hubei province and 2628 people in Guangdong province. One-way ANOVA was used to compare the total medical expense, out-of-pocket （OOP） expense and hospital stay between variables. A multiple linear regression analysis was done to identify possible risk factors of total medical expense. The results showed that the average total medical expense per capita was 5709.89 yuan, and the medical expense per capita was 7053.58 and 4555.97 yuan in Guangdong province and Hubei province, respectively. The medical expense of hypertensive inpatients decreased from 7222.32 yuan in 2012 to 4894.66 yuan in 2013. There were no significant differences in medical expenses between different genders of hypertensive patients （P〉0.05）. People of different ages, provinces, medical insurances and medical institution levels showed significant differences in medical expenses. The government should increase the investment in chronic disease management and treatment in the central and western regions to narrow the gap with the eastern region. Medical insurance fund payment should be improved to ensure the fairness of the use of medical services in different medical insurances. And measures should be taken to encourage chronic patients to visit primary medical institutions to effectively reduce medical expenses.展开更多
Leaf functional traits are adaptations that enable plants to live under various environmental conditions. This study aims to determine the differences in leaf functional traits among plants grouped by growth habit, le...Leaf functional traits are adaptations that enable plants to live under various environmental conditions. This study aims to determine the differences in leaf functional traits among plants grouped by growth habit, leaf life span,leaf lifestyle, leaf form, and origin. Specific leaf area（SLA） of perennial or evergreen species was lower than that of annual or deciduous species because longer-lived leaves of perennial or evergreen species require more investment in structural integrity and/or defense against disturbances, especially with any resource constraint. SLA of large individuals was lower than that of small individuals. The low SLA in large individuals can improve their response to changing light and water conditions because increasing plant height is advantageous for light competition, but it can also impose a cost in terms of structural support and water transport. Petioles of plants with compound leaves were significantly longer than those of simple leaves because branching is expensive in terms of gaining height. SLA of plants increased with increasing invasiveness accordingly, and SLA of invasive plants was higher than that of their native congeners because invasive plants should invest more biomass on leaf growth rather than leaf structures per unit area to achieve a higher growth rate.Overall, variation in leaf functional traits among different groups may play an adaptive role in the successful survival of plants under diverse environments because leaf functional traits can lead to pronounced effects on leaf function,especially the acquisition and use of light. Plant species with different growth and leaf traits balance resource acquisition and leaf construction to minimize trade-offs and achieve fitness advantages in their natural habitat.展开更多
The paper deals with the application of multiwall carbon nanotubes(CNTs) to the adsorption of dyes from wastewater. Textile dyes are dangerous and diffused pollutant in wastewater, and the paper results confirmed the ...The paper deals with the application of multiwall carbon nanotubes(CNTs) to the adsorption of dyes from wastewater. Textile dyes are dangerous and diffused pollutant in wastewater, and the paper results confirmed the good adsorption ability of CNTs, with respect to classic active carbon, even for different dye types. The effect of surface treatments of CNTs was primarily investigated, revealing that neither the presence of residual catalyst nor common surface treatment(oxidation) affects the CNT's performances. Therefore less expensive nonpurified CNTs were assessed as good and economically convenient alternative for the process. In order to gain in generality in adsorption kinetic modelling, the parameters of the "best fitting" pseudo-second order model have been correlated to the main process variables(the dye initial concentration and the specific mass of CNTs.) setting-up a predictive kinetic model useful design new application of these materials in currently operating industrial operations for adsorption. In addition, isothermal data were used to screen all the relevant adsorption isotherms models and the Temkin model was confirmed as the more effective to accurately fit equilibrium data for any of the considered different dye types.展开更多
AIM： To figure out the contributed factors of the hospitalization expenses of senile cataract patients（HECP） and build up an area-specified senile cataract diagnosis related group（DRG） of Shanghai thereby formula...AIM： To figure out the contributed factors of the hospitalization expenses of senile cataract patients（HECP） and build up an area-specified senile cataract diagnosis related group（DRG） of Shanghai thereby formulating the reference range of HECP and providing scientific basis for the fair use and supervision of the health care insurance fund.METHODS： The data was collected from the first page of the medical records of 22 097 hospitalized patients from tertiary hospitals in Shanghai from 2010 to 2012 whose major diagnosis were senile cataract. Firstly, we analyzed the influence factors of HECP using univariate and multivariate analysis. DRG grouping was conducted according to the exhaustive Chi-squared automatic interaction detector（E-CHAID） model, using HECP as target variable. Finally we evaluated the grouping results using non-parametric test such as Kruskal-Wallis H test, RIV, CV, etc.RESULTS： The 6 DRGs were established as well as criterion of HECP, using age, sex, type of surgery and whether complications/comorbidities occurred as the key variables of classification node of senile cataract cases.CONCLUSION： The grouping of senile cataract cases based on E-CHAID algorithm is reasonable. And the criterion of HECP based on DRG can provide a feasible way of management in the fair use and supervision of medical insurance fund.展开更多
Osteoarthritis(OA)presents a growing health concern,with substantial societal and healthcare burdens.Current management focuses on symptom relief,lacking disease-modifying options.Emerging research suggests the sodium...Osteoarthritis(OA)presents a growing health concern,with substantial societal and healthcare burdens.Current management focuses on symptom relief,lacking disease-modifying options.Emerging research suggests the sodium channel Nav1.7 as a pivotal target in OA treatment.Preclinical studies demonstrate carbamazepine's efficacy in Nav1.7 blockade,offering significant joint protection in animal models.However,human trials are needed to validate these findings.Carbamazepine's repurposing holds promise for OA management,potentially revolutionizing treatment paradigms.Further research is essential to bridge the gap between preclinical evidence and clinical application,offering hope for improved OA management and enhanced patient quality of life.展开更多
Saffron is the most precious and expensive agricultural product. A dehydration treatment is necessary to convert Crocus sativus L. stigmas into saffron spice. To the best of our knowledge, no information on mass trans...Saffron is the most precious and expensive agricultural product. A dehydration treatment is necessary to convert Crocus sativus L. stigmas into saffron spice. To the best of our knowledge, no information on mass transfer parameters of saffron stigmas is available in the literature. This study aimed at investigating the moisture transfer parameters and quality attributes of saffron stigmas under infrared treatment at different temperatures（60,70, …, 110 ℃）. It was observed that the dehydration process of the samples occurred in a short accelerating rate period at the start followed by a falling rate period. The effective moisture diffusivity and convective mass transfer coefficient were determined by using the Dincer and Dost model. The diffusivity values varied from1.1103 × 10^-10m^2·s^-1to 4.1397 × 10^-10m^2·s^-1 and mass transfer coefficient varied in the range of 2.6433 × 10^-7–8.7203 × 10^-7m·s^-1. The activation energy was obtained to be 27.86 kJ·mol^-1. The quality assessment results showed that the total crocin content increased, when the temperature increased up to90 ℃ but, in higher temperatures, the amount of crocin decreased slightly. The total safranal content of the samples decreased slightly when drying temperature increased from 60 ℃ to 70 ℃ and then continuously increased up to 110 ℃. Also, the amount of picrocrocin increased from 83.1 to 93.3 as the drying temperature increased from 60 ℃ to 100 ℃.展开更多
文摘Cardiovascular diseases(CVD)and their risk factors are exerting an increasingly significant impact on public health,and the incidence rate of CVD continues to rise.This article provides an interpretation of essentials from the newly published Annual Report on Cardiovascular Health and Diseases in China(2024),aiming to offer scientific evidence for CVD prevention,treatment,and the formulation of relevant policies.
文摘IN the Shanghai Jewish Refugees Museum,a beautiful handbag is waiting for its owner in a display cabinet.The handbag belongs to a Jewish couple.When they sought refuge in Shanghai during World War II,they pawned the handbag to Jin Wenzhen’s grandfather in exchange for their child’s medical expenses.He lent the couple the cash equivalent of one month’s revenue from his rice shop,but then never saw them again.
基金Sponsored by Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(Grant No.2022L294)Taiyuan University of Science and Technology Scientific Research Initial Funding(Grant Nos.W2022018,W20242012)Foundamental Research Program of Shanxi Province(Grant No.202403021212170).
文摘In recent years,surrogate models derived from genuine data samples have proven to be efficient in addressing optimization challenges that are costly or time⁃intensive.However,the individuals in the population become indistinguishable as the curse of dimensionality increases in the objective space and the accumulation of surrogate approximated errors.Therefore,in this paper,each objective function is modeled using a radial basis function approach,and the optimal solution set of the surrogate model is located by the multi⁃objective evolutionary algorithm of strengthened dominance relation.The original objective function values of the true evaluations are converted to two indicator values,and then the surrogate models are set up for the two performance indicators.Finally,an adaptive infill sampling strategy that relies on approximate performance indicators is proposed to assist in selecting individuals for real evaluations from the potential optimal solution set.The algorithm is contrasted against several advanced surrogate⁃assisted evolutionary algorithms on two suites of test cases,and the experimental findings prove that the approach is competitive in solving expensive many⁃objective optimization problems.
文摘沿革为了刺激技术创新,美国很早就制定颁布了相应的税收优惠制度。1954年美国《国内税收法典》就确立了研发费用扣除制度(174节)。但是令人遗憾的是,研发费用扣除制度没有带来预想的效果。数据显示,研发投资与国民生产总值的比例从1968年的2.01%下降到1975年的1.58%。更重要的是,美国将其大部分研发投资都用于国防工业。与其他发达国家相比,它的非国防研发支出(civilian research expense)是比较少的。1970-1980年间,美国的研发投入与GDP的比例始终在1.5%到2%之间徘徊。而在同时段的德国和日本,这一比例从来没有低过1.9%。
文摘英汉语均广泛使用比较级,但英语用比较级更广泛些,花样也多些。因此,相对说来,英译汉困难多些。其实汉译英也不易,只是一般采用平铺直叙的译法,不常采用英语丰富多采的表达方式来翻译。例如下面提到的“绝不坏”,一般就译为“not bat at all”,“not absolutely bad”或“quite good”,很少译为“no less good”。又如“这种布由于很漂亮,也就不算贵了”,一般直译为“This
文摘目的基于上海市近年结核病诊疗费用减免政策,探索耐多药结核病(multidrug resistant tuberculosis,MDR-TB)患者疾病经济负担及其影响因素,为优化MDR-TB诊疗费用减免政策和综合管理模式提供依据。方法收集上海市2017—2019年确诊MDR-TB患者情况和诊疗费用减免情况数据,开展针对疾病经济负担的问卷调查,建立涵盖患者人口和社会经济情况、临床特征、疾病经济负担和诊疗费用减免情况数据库,明确患者疾病经济负担和灾难性卫生支出(catastrophic health expenditure)发生情况。以多元线性回归法分析可能影响患者疾病经济负担的因素,以多因素logistic回归法分析不同比例下灾难性卫生支出发生的影响因素。结果196例纳入研究分析的MDR-TB患者平均年龄为(44±16)岁,男性139例(占70.9%),上海户籍占46.4%,49%的患者为家庭主要劳动力。治疗期间,患者自付诊疗费用中位数为4.0(四分位数区间2.0~6.5)万元。113例患者获得减免诊疗,减免费用中位数为2.6(四分位数区间1.3~4.9)万元。若自付费用占家庭年收入的40%及以上,有47.8%的患者会发生灾难性支出;若不考虑减免政策,有59.8%的患者发生灾难性卫生支出。上海户籍(OR=0.3,95%CI为0.1~1.0)、更低家庭收入水平(P_(trend)=0.002)、医疗保险类型[(农村合作医疗保险/外来人口综合保险(OR=13.3,95%CI为1.0~171.2),无医疗保险(OR=17.5,95%CI为2.7~113.0)]和既往结核病治疗史(OR=3.3,95%CI为1.1~10.0)可能影响灾难性卫生支出的发生。结论上海市MDR-TB患者的自付诊疗费用较高。医疗保障力度较小和家庭经济情况不佳的患者更易发生高额自付费用,导致灾难性卫生支出。上海市MDR-TB诊疗费用减免政策有效降低了患者的经济负担。
文摘有报道称,中国财富性别差距日益扩大,女性不仅被＂剩下＂,而且被＂无视＂。
Shang Wen,a single 32-year-old,a three-year-old’s mother,is a rarity1in China,mainly because her parents helped her purchase her own house in 2004.＂Property was not too expensive then,and my parents had no idea that the market would take off2,＂says Shang.Little did she know that this investment could end up paying off years later,
文摘目的评价药品集中带量采购对糖尿病患者住院总费用及各类构成费用的影响。方法基于研究医院的9852份糖尿病患者病案首页数据,整理患者基本信息、医疗服务利用信息及各项医疗费用信息,综合运用普通最小二乘法(ordinary least square,OLS)和倾向性得分匹配法(propensity score matching,PSM)进行数据分析。结果集中带量采购政策确实能够降低糖尿病住院患者的药品费用(t=-2.27,P<0.05),但是对住院总费用、医疗服务性费用影响不显著。OLS回归低估了药品集中带量采购对患者检查化验耗材费用的增费效应(t=2.26,P<0.05)。结论在进一步加强宣传教育的同时,要有序扩大药品集中带量采购,系统推动医药领域集约式改革,持续放大改革红利,实现患者总体医疗负担减轻,让政策福利遍及更多患者。
文摘Modern engineering design optimization often relies on computer simulations to evaluate candidate designs, a setup which results in expensive black-box optimization problems. Such problems introduce unique challenges, which has motivated the application of metamodel-assisted computational intelligence algorithms to solve them. Such algorithms combine a computational intelligence optimizer which employs a population of candidate solutions, with a metamodel which is a computationally cheaper approximation of the expensive computer simulation. However, although a variety of metamodels and optimizers have been proposed, the optimal types to employ are problem dependant. Therefore, a priori prescribing the type of metamodel and optimizer to be used may degrade its effectiveness. Leveraging on this issue, this study proposes a new computational intelligence algorithm which autonomously adapts the type of the metamodel and optimizer during the search by selecting the most suitable types out of a family of candidates at each stage. Performance analysis using a set of test functions demonstrates the effectiveness of the proposed algorithm, and highlights the merit of the proposed adaptation approach.
基金supported in part by the National Natural Science Foundation of China(72171172,62088101)in part by the Shanghai Science and Technology Major Special Project of Shanghai Development and Reform Commission(2021SHZDZX0100)+2 种基金in part by the Shanghai Commission of Science and Technology(19511132100,19511132101)in part by the China Scholarship Councilin part by the Deanship of Scientific Research(DSR)at King Abdulaziz University(KAU),Jeddah,Saudi Arabia(FP-146-43)。
文摘This study presents an autoencoder-embedded optimization(AEO)algorithm which involves a bi-population cooperative strategy for medium-scale expensive problems(MEPs).A huge search space can be compressed to an informative lowdimensional space by using an autoencoder as a dimension reduction tool.The search operation conducted in this low space facilitates the population with fast convergence towards the optima.To strike the balance between exploration and exploitation during optimization,two phases of a tailored teaching-learning-based optimization(TTLBO)are adopted to coevolve solutions in a distributed fashion,wherein one is assisted by an autoencoder and the other undergoes a regular evolutionary process.Also,a dynamic size adjustment scheme according to problem dimension and evolutionary progress is proposed to promote information exchange between these two phases and accelerate evolutionary convergence speed.The proposed algorithm is validated by testing benchmark functions with dimensions varying from 50 to 200.As indicated in our experiments,TTLBO is suitable for dealing with medium-scale problems and thus incorporated into the AEO framework as a base optimizer.Compared with the state-of-the-art algorithms for MEPs,AEO shows extraordinarily high efficiency for these challenging problems,t hus opening new directions for various evolutionary algorithms under AEO to tackle MEPs and greatly advancing the field of medium-scale computationally expensive optimization.
基金This project was supported by Key projects of National Natural Science Foundation of China （No.71333005）.
文摘Along with the development of society and the rapid economic growth in the past decades, hypertension and other chronic diseases have become important reasons for people＇s poverty caused by illness in China. This study collected a total of 5857 people from 2010 to 2013 randomly from the database of the Medical Insurance Department （MID）, including 3229 people in Hubei province and 2628 people in Guangdong province. One-way ANOVA was used to compare the total medical expense, out-of-pocket （OOP） expense and hospital stay between variables. A multiple linear regression analysis was done to identify possible risk factors of total medical expense. The results showed that the average total medical expense per capita was 5709.89 yuan, and the medical expense per capita was 7053.58 and 4555.97 yuan in Guangdong province and Hubei province, respectively. The medical expense of hypertensive inpatients decreased from 7222.32 yuan in 2012 to 4894.66 yuan in 2013. There were no significant differences in medical expenses between different genders of hypertensive patients （P〉0.05）. People of different ages, provinces, medical insurances and medical institution levels showed significant differences in medical expenses. The government should increase the investment in chronic disease management and treatment in the central and western regions to narrow the gap with the eastern region. Medical insurance fund payment should be improved to ensure the fairness of the use of medical services in different medical insurances. And measures should be taken to encourage chronic patients to visit primary medical institutions to effectively reduce medical expenses.
基金supported by the National Natural Science Foundation of China(31300343)Natural Science Foundation of Jiangsu Province,China(BK20130500)Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment,Research Foundation for Advanced Talents,Jiangsu University(12JDG086)
文摘Leaf functional traits are adaptations that enable plants to live under various environmental conditions. This study aims to determine the differences in leaf functional traits among plants grouped by growth habit, leaf life span,leaf lifestyle, leaf form, and origin. Specific leaf area（SLA） of perennial or evergreen species was lower than that of annual or deciduous species because longer-lived leaves of perennial or evergreen species require more investment in structural integrity and/or defense against disturbances, especially with any resource constraint. SLA of large individuals was lower than that of small individuals. The low SLA in large individuals can improve their response to changing light and water conditions because increasing plant height is advantageous for light competition, but it can also impose a cost in terms of structural support and water transport. Petioles of plants with compound leaves were significantly longer than those of simple leaves because branching is expensive in terms of gaining height. SLA of plants increased with increasing invasiveness accordingly, and SLA of invasive plants was higher than that of their native congeners because invasive plants should invest more biomass on leaf growth rather than leaf structures per unit area to achieve a higher growth rate.Overall, variation in leaf functional traits among different groups may play an adaptive role in the successful survival of plants under diverse environments because leaf functional traits can lead to pronounced effects on leaf function,especially the acquisition and use of light. Plant species with different growth and leaf traits balance resource acquisition and leaf construction to minimize trade-offs and achieve fitness advantages in their natural habitat.
文摘The paper deals with the application of multiwall carbon nanotubes(CNTs) to the adsorption of dyes from wastewater. Textile dyes are dangerous and diffused pollutant in wastewater, and the paper results confirmed the good adsorption ability of CNTs, with respect to classic active carbon, even for different dye types. The effect of surface treatments of CNTs was primarily investigated, revealing that neither the presence of residual catalyst nor common surface treatment(oxidation) affects the CNT's performances. Therefore less expensive nonpurified CNTs were assessed as good and economically convenient alternative for the process. In order to gain in generality in adsorption kinetic modelling, the parameters of the "best fitting" pseudo-second order model have been correlated to the main process variables(the dye initial concentration and the specific mass of CNTs.) setting-up a predictive kinetic model useful design new application of these materials in currently operating industrial operations for adsorption. In addition, isothermal data were used to screen all the relevant adsorption isotherms models and the Temkin model was confirmed as the more effective to accurately fit equilibrium data for any of the considered different dye types.
基金Supported by the Key Research and Development Program of Hunan Province(No.2017SK2011)
文摘AIM： To figure out the contributed factors of the hospitalization expenses of senile cataract patients（HECP） and build up an area-specified senile cataract diagnosis related group（DRG） of Shanghai thereby formulating the reference range of HECP and providing scientific basis for the fair use and supervision of the health care insurance fund.METHODS： The data was collected from the first page of the medical records of 22 097 hospitalized patients from tertiary hospitals in Shanghai from 2010 to 2012 whose major diagnosis were senile cataract. Firstly, we analyzed the influence factors of HECP using univariate and multivariate analysis. DRG grouping was conducted according to the exhaustive Chi-squared automatic interaction detector（E-CHAID） model, using HECP as target variable. Finally we evaluated the grouping results using non-parametric test such as Kruskal-Wallis H test, RIV, CV, etc.RESULTS： The 6 DRGs were established as well as criterion of HECP, using age, sex, type of surgery and whether complications/comorbidities occurred as the key variables of classification node of senile cataract cases.CONCLUSION： The grouping of senile cataract cases based on E-CHAID algorithm is reasonable. And the criterion of HECP based on DRG can provide a feasible way of management in the fair use and supervision of medical insurance fund.
文摘Osteoarthritis(OA)presents a growing health concern,with substantial societal and healthcare burdens.Current management focuses on symptom relief,lacking disease-modifying options.Emerging research suggests the sodium channel Nav1.7 as a pivotal target in OA treatment.Preclinical studies demonstrate carbamazepine's efficacy in Nav1.7 blockade,offering significant joint protection in animal models.However,human trials are needed to validate these findings.Carbamazepine's repurposing holds promise for OA management,potentially revolutionizing treatment paradigms.Further research is essential to bridge the gap between preclinical evidence and clinical application,offering hope for improved OA management and enhanced patient quality of life.
文摘Saffron is the most precious and expensive agricultural product. A dehydration treatment is necessary to convert Crocus sativus L. stigmas into saffron spice. To the best of our knowledge, no information on mass transfer parameters of saffron stigmas is available in the literature. This study aimed at investigating the moisture transfer parameters and quality attributes of saffron stigmas under infrared treatment at different temperatures（60,70, …, 110 ℃）. It was observed that the dehydration process of the samples occurred in a short accelerating rate period at the start followed by a falling rate period. The effective moisture diffusivity and convective mass transfer coefficient were determined by using the Dincer and Dost model. The diffusivity values varied from1.1103 × 10^-10m^2·s^-1to 4.1397 × 10^-10m^2·s^-1 and mass transfer coefficient varied in the range of 2.6433 × 10^-7–8.7203 × 10^-7m·s^-1. The activation energy was obtained to be 27.86 kJ·mol^-1. The quality assessment results showed that the total crocin content increased, when the temperature increased up to90 ℃ but, in higher temperatures, the amount of crocin decreased slightly. The total safranal content of the samples decreased slightly when drying temperature increased from 60 ℃ to 70 ℃ and then continuously increased up to 110 ℃. Also, the amount of picrocrocin increased from 83.1 to 93.3 as the drying temperature increased from 60 ℃ to 100 ℃.
