Objective: To study the ultrastructure and biological characteristics of expansive type of hepatocellular carcinoma (EHCC). Methods: Examination of EHCC and infiltrative type of hepatocellular carcinoma (IHCC) (each 2...Objective: To study the ultrastructure and biological characteristics of expansive type of hepatocellular carcinoma (EHCC). Methods: Examination of EHCC and infiltrative type of hepatocellular carcinoma (IHCC) (each 20 cases) by electron microscope (EM) to compare their ultrastructure. Results: The 40 cases were divided into 3 groups: 16 cases of well differentiated EIICC, 4 cases of poorly differentiated EHCC, and 20 cases of poorly differentiated IHCC. The ultrastructure of well differentiated EHCC was similar to the surrounding non-cancer hepatocytes; the characteristics of them were as follows: 1. Cell membrane was developed well and cell border was clear; 2. Round nucleus was of regular shape; nuclear membrane was smooth; 3. Nucleoli were round, regular and bigger than normal; and 4. Plentiful endoplasmic reticulum and mitochondria were well developed. The ultrastructure of poorly differentiated EHCC and IHCC were identical: 1. Membrane was poorly developed; 2. Irregular nuclei were deeply indented or lobulated and many pseudoinclusions were seen; 3. Majority of the nucleoli were big, sponges or ring-formed; 4. Organelles were plentiful or scanty and tended to be degenerated. Conclusion: Most of the EHCC were mature by EM observation; this explained the EHCC’s slow growth pattern, but some still had invasive potential.展开更多
Objective: to observe and study the clinical manifestations and symptoms of patients with dilated cardiomyopathy with kidney-yang deficiency after combined treatment of Chinese and western medicine. Methods: the patie...Objective: to observe and study the clinical manifestations and symptoms of patients with dilated cardiomyopathy with kidney-yang deficiency after combined treatment of Chinese and western medicine. Methods: the patients with dilated cardiomyopathy with kidney-yang deficiency treated in our hospital in recent one year were selected, and the clinical data were collected, and the clinical therapeutic effect of the patients was observed. A total of 100 patients were collected and included in the study. After reviewing the clinical drug treatment characteristics of the patients, we randomly divided them into two groups: 50 patients in the observation group were treated with combination of traditional Chinese medicine and western medicine, and 50 patients in the control group were treated with single western medicine. The drug types were oral captopril and oral metoprolol tartrate. After the patient completed the whole treatment process, the clinical treatment effect of the patient was observed. Results: the total incidence of adverse reactions in the observation group and the control group was 8.00% (4/50). The total effective rate of the control group was 80.00%, and the total effective data of the observation group was 98.00%. After treatment, BNP: (27.33±4.39) pg/ml, LVEDd: (61.02±5.19) mm, LVEF: (42.37±4.53)% in the observation group, BNP:(40.50±7.99)pg/ml, LVEDd:(64.33±3.11)mm, LVEF:(37.12±5.59)% . Conclusion: for patients with dilated cardiomyopathy with kidney-yang deficiency, single western medicine has certain therapeutic effect. At this time, adding traditional Chinese medicine on the basis of western medicine can improve clinical therapeutic effect, reduce plasma brain natriuretic peptide and cardiac function indexes, and make patients life quality better.展开更多
In this paper, the author discusses the multiple positive solutions for an infinite boundary value problem of first order impulsive superlinear integro-differential equations on the half line by means of the fixed poi...In this paper, the author discusses the multiple positive solutions for an infinite boundary value problem of first order impulsive superlinear integro-differential equations on the half line by means of the fixed point theorem of cone expansion and compression with norm type.展开更多
The existence and multiplicity of positive solutions to a periodic boundary value problem for nonlinear third-order ordinary differential equation are established,based on the zero point theorem concerning cone expans...The existence and multiplicity of positive solutions to a periodic boundary value problem for nonlinear third-order ordinary differential equation are established,based on the zero point theorem concerning cone expansion and compression of order type.Our main approach is different from the previous papers on the existence of multiple positive solutions to the similar problem.展开更多
文摘Objective: To study the ultrastructure and biological characteristics of expansive type of hepatocellular carcinoma (EHCC). Methods: Examination of EHCC and infiltrative type of hepatocellular carcinoma (IHCC) (each 20 cases) by electron microscope (EM) to compare their ultrastructure. Results: The 40 cases were divided into 3 groups: 16 cases of well differentiated EIICC, 4 cases of poorly differentiated EHCC, and 20 cases of poorly differentiated IHCC. The ultrastructure of well differentiated EHCC was similar to the surrounding non-cancer hepatocytes; the characteristics of them were as follows: 1. Cell membrane was developed well and cell border was clear; 2. Round nucleus was of regular shape; nuclear membrane was smooth; 3. Nucleoli were round, regular and bigger than normal; and 4. Plentiful endoplasmic reticulum and mitochondria were well developed. The ultrastructure of poorly differentiated EHCC and IHCC were identical: 1. Membrane was poorly developed; 2. Irregular nuclei were deeply indented or lobulated and many pseudoinclusions were seen; 3. Majority of the nucleoli were big, sponges or ring-formed; 4. Organelles were plentiful or scanty and tended to be degenerated. Conclusion: Most of the EHCC were mature by EM observation; this explained the EHCC’s slow growth pattern, but some still had invasive potential.
文摘Objective: to observe and study the clinical manifestations and symptoms of patients with dilated cardiomyopathy with kidney-yang deficiency after combined treatment of Chinese and western medicine. Methods: the patients with dilated cardiomyopathy with kidney-yang deficiency treated in our hospital in recent one year were selected, and the clinical data were collected, and the clinical therapeutic effect of the patients was observed. A total of 100 patients were collected and included in the study. After reviewing the clinical drug treatment characteristics of the patients, we randomly divided them into two groups: 50 patients in the observation group were treated with combination of traditional Chinese medicine and western medicine, and 50 patients in the control group were treated with single western medicine. The drug types were oral captopril and oral metoprolol tartrate. After the patient completed the whole treatment process, the clinical treatment effect of the patient was observed. Results: the total incidence of adverse reactions in the observation group and the control group was 8.00% (4/50). The total effective rate of the control group was 80.00%, and the total effective data of the observation group was 98.00%. After treatment, BNP: (27.33±4.39) pg/ml, LVEDd: (61.02±5.19) mm, LVEF: (42.37±4.53)% in the observation group, BNP:(40.50±7.99)pg/ml, LVEDd:(64.33±3.11)mm, LVEF:(37.12±5.59)% . Conclusion: for patients with dilated cardiomyopathy with kidney-yang deficiency, single western medicine has certain therapeutic effect. At this time, adding traditional Chinese medicine on the basis of western medicine can improve clinical therapeutic effect, reduce plasma brain natriuretic peptide and cardiac function indexes, and make patients life quality better.
文摘In this paper, the author discusses the multiple positive solutions for an infinite boundary value problem of first order impulsive superlinear integro-differential equations on the half line by means of the fixed point theorem of cone expansion and compression with norm type.
基金supported by the National Natural Science Foundation of China(10971179)the Natural Science Foundation of Changzhou University(JS201008)
文摘The existence and multiplicity of positive solutions to a periodic boundary value problem for nonlinear third-order ordinary differential equation are established,based on the zero point theorem concerning cone expansion and compression of order type.Our main approach is different from the previous papers on the existence of multiple positive solutions to the similar problem.