Guided bone regeneration (GBR) often utilizes a combination of autologous bone grafts, deproteinized bovine bone mineral(DBBM), and collagen membranes. DBBM and collagen membranes pre-coated with bone-conditioned medi...Guided bone regeneration (GBR) often utilizes a combination of autologous bone grafts, deproteinized bovine bone mineral(DBBM), and collagen membranes. DBBM and collagen membranes pre-coated with bone-conditioned medium (BCM) extracted from locally harvested autologous bone chips have shown great regenerative potential in GBR. However, the underlying molecular mechanism remains largely unknown. Here, we investigated the composition of BCM and its activity on the osteogenic potential of mesenchymal stromal cells. We detected a fast and significant (P <0.001) release of transforming growth factor-β1 (TGF-β1) from autologous bone within 10 min versus a delayed bone morphogenetic protein-2 (BMP-2) release from 40 min onwards. BCMs harvested within short time periods (10, 20, or 40 min), corresponding to the time of a typical surgical procedure, significantly increased the proliferative activity and collagen matrix production of BCM-treated cells. Long-term (1, 3, or 6 days)-extracted BCMs promoted the later stages of osteoblast differentiation and maturation. Short-term-extracted BCMs, in which TGF-β1 but no BMP-2was detected, reduced the expression of the late differentiation marker osteocalcin. However, when both growth factors were present simultaneously in the BCM, no inhibitory effects on osteoblast differentiation were observed, suggesting a synergistic TGF-β1/BMP-2 activity. Consequently, in cells that were co-stimulated with recombinant TGF-β1 and BMP-2, we showed a significant stimulatory and dose-dependent effect of TGF-β1 on BMP-2-induced osteoblast differentiation due to prolonged BMP signaling and reduced expression of the BMP-2 antagonist noggin. Altogether, our data provide new insights into the molecular mechanisms underlying the favorable outcome from GBR procedures using BCM, derived from autologous bone grafts.展开更多
WANGFUJlNG Street is one of China＇s most renowned shopping streets. The area＇s commercial history can date back many centuries. Today, the street located in the eastern-central side of the city is always choked with...WANGFUJlNG Street is one of China＇s most renowned shopping streets. The area＇s commercial history can date back many centuries. Today, the street located in the eastern-central side of the city is always choked with happy＇shoppers and tourists from home and abroad. One August morning, people found that the street. congested as usual, had somehow changed - in the middle stood a row of panels which displayed pictures representing another country. ＂The photo exhibition, titled ＇South Africa in Beijing,＇ seeks to showcase the very rich and diverse South African culture and heritage to the broad Chinese public,＂ said Dr. Bheki Langa, South Africa＇s Ambassador to China.展开更多
A New Chapter of the Century-Old Palace Museum Oriental Outlook Issue 24,2025 The Palace Museum,the imperial palace of the Ming and Qing dynasties(1368-1911),opened to the public in 1925.Rather than a group of static ...A New Chapter of the Century-Old Palace Museum Oriental Outlook Issue 24,2025 The Palace Museum,the imperial palace of the Ming and Qing dynasties(1368-1911),opened to the public in 1925.Rather than a group of static ancient buildings,it stands today as a dynamic cultural organism filled with invaluable collections of cultural relics preserved by generations of artisans and now displayed to the world through digital technology in long-lasting exhibitions.展开更多
Obese individuals who subsequently sustain a traumatic brain injury(TBI)exhibit worsened outcomes including longer periods of rehabilitation(Eagle et al.,2023).In obese individuals,prolonged symptomology is associated...Obese individuals who subsequently sustain a traumatic brain injury(TBI)exhibit worsened outcomes including longer periods of rehabilitation(Eagle et al.,2023).In obese individuals,prolonged symptomology is associated with increased levels of circulato ry pro-inflammatory marke rs up to 1 year postTBI(Eagle et al.,2023).展开更多
Chinese entrepreneurs can be found scattered across the globe, all with an innate sense of business that has made them a potent force ininternational trade . To illustrate the importance of entrepreneurs, at the 100th...Chinese entrepreneurs can be found scattered across the globe, all with an innate sense of business that has made them a potent force ininternational trade . To illustrate the importance of entrepreneurs, at the 100th Chinese Export Commodities Fair (CECF) held in Guangzhou in October, Premier Wen Jiabao met with Zheng Mingru, Permanent Honorary President of the Wor ld Chinese Entrepr eneurs General Association (WCEGA), and awar ded him a medal for his sterling wor k in connecting Chinese business people wo...展开更多
2024年日本机床展览会(JIMTOF2024)于2024年11月5~10日在东京Tokyo Big Sight举办,展出面积118540平方米。展会以“技术传承提供无限可能(Technologies passed down to the future offer unlimited possibilities)”为主题。
On January 11,2025,the 2025 Bejing Roundtable Meeting for International Exhibition Organisations was held in Beijing.The event was co-hosted by the CCPIT Bejing,the Bejing Municipal Commerce Bureau,the Shunyi District...On January 11,2025,the 2025 Bejing Roundtable Meeting for International Exhibition Organisations was held in Beijing.The event was co-hosted by the CCPIT Bejing,the Bejing Municipal Commerce Bureau,the Shunyi District People's Government and the Beijing Chamber of International Commerce.展开更多
CT:As one of the exhibition owners,what were the key factors that led CEMATEX to decide to host ITMA ASIA 2025 in Singapore?Alex Zucchi:In response to requests from our members for an exhibition in Asia outside of Chi...CT:As one of the exhibition owners,what were the key factors that led CEMATEX to decide to host ITMA ASIA 2025 in Singapore?Alex Zucchi:In response to requests from our members for an exhibition in Asia outside of China,we decided to hold a combined exhibition in a second Asian location to support our members.It will also provide a reputable sourcing platform to help textile and garment manufacturers in the region modernize their operations.CT:Exhibition booths sold out very quickly.What motivates companies to participate in the exhibition?Alex Zucchi:The Singapore edition targets the South and Southeast Asia markets,as well as the Middle East.These are key textile and garment producing hubs.Hence,machinery makers are keen to reach out to buyers in the region.展开更多
CT:As the first ITMA ASIA+CITME exhibition held in Singapore,what are the highlights of this show?Are there any activities planned for the exhibition?Charles Beauduin:The first combined exhibition in Singapore will fe...CT:As the first ITMA ASIA+CITME exhibition held in Singapore,what are the highlights of this show?Are there any activities planned for the exhibition?Charles Beauduin:The first combined exhibition in Singapore will feature the unique selling proposition of an ITMA exhibition,such as live machinery demonstrations,and exhibits clustered in product sectors.As it is only a four-day exhibition,our exhibitors would like to concentrate on business and to present their technologies and solutions to the region’s buyers who don’t visit our Europe or China exhibitions.There is a highlight which will add value to our participants’experience-The ITMA Sustainability Forum which is presented by CEMATEX on the third day of the exhibition.展开更多
On May 16th,the press conference of the 8th China(ORDOS)International Cashmere and Wool Exhibition organized by China Wool Textile Association was held in Inner Mongolia Grand Hotel in Beijing.The 8th China(ORDOS)Inte...On May 16th,the press conference of the 8th China(ORDOS)International Cashmere and Wool Exhibition organized by China Wool Textile Association was held in Inner Mongolia Grand Hotel in Beijing.The 8th China(ORDOS)International Cashmere and Wool Exhibition will be held in the National Fitness Center of Dongsheng District,Ordos City from July 18th to 20th with the theme of“Cashmere Chain Links the World,Intelligence Empowers the Future”.展开更多
Cultural artifacts exhibitions are among the most profound and appealing forms of cultural exchange.These exhibitions serve as an important bridge for fostering friendly relations between countries and bringing people...Cultural artifacts exhibitions are among the most profound and appealing forms of cultural exchange.These exhibitions serve as an important bridge for fostering friendly relations between countries and bringing people closer together.展开更多
The“Black Myth:Wukong Encounter Shanxi”digital art exhibition opened in Taiyuan,Shanxi Province,on October 31.The show blended Chinese video game Black Myth:Wukong with miniature ancient architecture,highlighting th...The“Black Myth:Wukong Encounter Shanxi”digital art exhibition opened in Taiyuan,Shanxi Province,on October 31.The show blended Chinese video game Black Myth:Wukong with miniature ancient architecture,highlighting the charm of Shanxi’s heritage.展开更多
Recently,SAMR issued four national standards in the exhibition services sector,including the newly developed GB/T 45704-2025,Guidelines for online exhibition services,and three revised standards.GB/T 45704-2025 addres...Recently,SAMR issued four national standards in the exhibition services sector,including the newly developed GB/T 45704-2025,Guidelines for online exhibition services,and three revised standards.GB/T 45704-2025 addresses the emerging online exhibition models.It provides guidelines for the whole exhibition process,and clarifies the requirements for service providers’capabilities,to promote the healthy development of this evolving industry.展开更多
The 51st China Beijing International Gifts,Premium and Houseware Exhibition(hereinafter referred to as the Gifts Exhibition) officially opened the kaleidoscope of creative gifts at China International Exhibition Cente...The 51st China Beijing International Gifts,Premium and Houseware Exhibition(hereinafter referred to as the Gifts Exhibition) officially opened the kaleidoscope of creative gifts at China International Exhibition Center (Chaoyang Pavilion) on March 20th.More than 900 exhibitors built an aesthetic corridor of quality life with 200,000 gifts.展开更多
From August 14 to 16,the 52nd China Beijing International Gifts,Premium&Houseware Exhibition(hereinafter referred to as Beijing Gift&Home)was held at the China International Exhibition Center(Chaoyang Pavilion...From August 14 to 16,the 52nd China Beijing International Gifts,Premium&Houseware Exhibition(hereinafter referred to as Beijing Gift&Home)was held at the China International Exhibition Center(Chaoyang Pavilion)in Beijing,China.As the annual grand finale of the northern gift industry.展开更多
From June 4 to 17,2025,the Harmony Together for a Friendly Future-Exhibition of Intermitioncil Youth Photography,jointly hosted by China Center of International Cultural Exchange and Tourism Promotion(CETP)nnd China C...From June 4 to 17,2025,the Harmony Together for a Friendly Future-Exhibition of Intermitioncil Youth Photography,jointly hosted by China Center of International Cultural Exchange and Tourism Promotion(CETP)nnd China Cultural Center in Copenhagen,was successfully held at the China Cultured Center in Copenhagen.展开更多
On March l3th,the three-day Intertextile Shanghai Apparel Fabrics-Spring Edition 2025 concluded successfully at the National Exhibition andConvention Center(Shanghai).This bustling event,carrying the expectationsof th...On March l3th,the three-day Intertextile Shanghai Apparel Fabrics-Spring Edition 2025 concluded successfully at the National Exhibition andConvention Center(Shanghai).This bustling event,carrying the expectationsof the industry,conveyed the enthusiasm for business cooperation in China'stextile industry at the beginning of 2025 through its exhibition data.展开更多
From June 4 to 17,2025.the Harmony Together for Friendly future-Exhibition of International Youth Photography.jointly Hosted by China Center for International Culture and Tourism Exchanges(CCICTE) and China Cultural C...From June 4 to 17,2025.the Harmony Together for Friendly future-Exhibition of International Youth Photography.jointly Hosted by China Center for International Culture and Tourism Exchanges(CCICTE) and China Cultural Center in Copenhagen.展开更多
基金supported by a grant from the ITI International Team for Implantology Foundation 1235_2017 to M.B.A
文摘Guided bone regeneration (GBR) often utilizes a combination of autologous bone grafts, deproteinized bovine bone mineral(DBBM), and collagen membranes. DBBM and collagen membranes pre-coated with bone-conditioned medium (BCM) extracted from locally harvested autologous bone chips have shown great regenerative potential in GBR. However, the underlying molecular mechanism remains largely unknown. Here, we investigated the composition of BCM and its activity on the osteogenic potential of mesenchymal stromal cells. We detected a fast and significant (P <0.001) release of transforming growth factor-β1 (TGF-β1) from autologous bone within 10 min versus a delayed bone morphogenetic protein-2 (BMP-2) release from 40 min onwards. BCMs harvested within short time periods (10, 20, or 40 min), corresponding to the time of a typical surgical procedure, significantly increased the proliferative activity and collagen matrix production of BCM-treated cells. Long-term (1, 3, or 6 days)-extracted BCMs promoted the later stages of osteoblast differentiation and maturation. Short-term-extracted BCMs, in which TGF-β1 but no BMP-2was detected, reduced the expression of the late differentiation marker osteocalcin. However, when both growth factors were present simultaneously in the BCM, no inhibitory effects on osteoblast differentiation were observed, suggesting a synergistic TGF-β1/BMP-2 activity. Consequently, in cells that were co-stimulated with recombinant TGF-β1 and BMP-2, we showed a significant stimulatory and dose-dependent effect of TGF-β1 on BMP-2-induced osteoblast differentiation due to prolonged BMP signaling and reduced expression of the BMP-2 antagonist noggin. Altogether, our data provide new insights into the molecular mechanisms underlying the favorable outcome from GBR procedures using BCM, derived from autologous bone grafts.
文摘WANGFUJlNG Street is one of China＇s most renowned shopping streets. The area＇s commercial history can date back many centuries. Today, the street located in the eastern-central side of the city is always choked with happy＇shoppers and tourists from home and abroad. One August morning, people found that the street. congested as usual, had somehow changed - in the middle stood a row of panels which displayed pictures representing another country. ＂The photo exhibition, titled ＇South Africa in Beijing,＇ seeks to showcase the very rich and diverse South African culture and heritage to the broad Chinese public,＂ said Dr. Bheki Langa, South Africa＇s Ambassador to China.
文摘A New Chapter of the Century-Old Palace Museum Oriental Outlook Issue 24,2025 The Palace Museum,the imperial palace of the Ming and Qing dynasties(1368-1911),opened to the public in 1925.Rather than a group of static ancient buildings,it stands today as a dynamic cultural organism filled with invaluable collections of cultural relics preserved by generations of artisans and now displayed to the world through digital technology in long-lasting exhibitions.
文摘Obese individuals who subsequently sustain a traumatic brain injury(TBI)exhibit worsened outcomes including longer periods of rehabilitation(Eagle et al.,2023).In obese individuals,prolonged symptomology is associated with increased levels of circulato ry pro-inflammatory marke rs up to 1 year postTBI(Eagle et al.,2023).
文摘Chinese entrepreneurs can be found scattered across the globe, all with an innate sense of business that has made them a potent force ininternational trade . To illustrate the importance of entrepreneurs, at the 100th Chinese Export Commodities Fair (CECF) held in Guangzhou in October, Premier Wen Jiabao met with Zheng Mingru, Permanent Honorary President of the Wor ld Chinese Entrepr eneurs General Association (WCEGA), and awar ded him a medal for his sterling wor k in connecting Chinese business people wo...
文摘2024年日本机床展览会(JIMTOF2024)于2024年11月5~10日在东京Tokyo Big Sight举办,展出面积118540平方米。展会以“技术传承提供无限可能(Technologies passed down to the future offer unlimited possibilities)”为主题。
文摘On January 11,2025,the 2025 Bejing Roundtable Meeting for International Exhibition Organisations was held in Beijing.The event was co-hosted by the CCPIT Bejing,the Bejing Municipal Commerce Bureau,the Shunyi District People's Government and the Beijing Chamber of International Commerce.
文摘CT:As one of the exhibition owners,what were the key factors that led CEMATEX to decide to host ITMA ASIA 2025 in Singapore?Alex Zucchi:In response to requests from our members for an exhibition in Asia outside of China,we decided to hold a combined exhibition in a second Asian location to support our members.It will also provide a reputable sourcing platform to help textile and garment manufacturers in the region modernize their operations.CT:Exhibition booths sold out very quickly.What motivates companies to participate in the exhibition?Alex Zucchi:The Singapore edition targets the South and Southeast Asia markets,as well as the Middle East.These are key textile and garment producing hubs.Hence,machinery makers are keen to reach out to buyers in the region.
文摘CT:As the first ITMA ASIA+CITME exhibition held in Singapore,what are the highlights of this show?Are there any activities planned for the exhibition?Charles Beauduin:The first combined exhibition in Singapore will feature the unique selling proposition of an ITMA exhibition,such as live machinery demonstrations,and exhibits clustered in product sectors.As it is only a four-day exhibition,our exhibitors would like to concentrate on business and to present their technologies and solutions to the region’s buyers who don’t visit our Europe or China exhibitions.There is a highlight which will add value to our participants’experience-The ITMA Sustainability Forum which is presented by CEMATEX on the third day of the exhibition.
文摘On May 16th,the press conference of the 8th China(ORDOS)International Cashmere and Wool Exhibition organized by China Wool Textile Association was held in Inner Mongolia Grand Hotel in Beijing.The 8th China(ORDOS)International Cashmere and Wool Exhibition will be held in the National Fitness Center of Dongsheng District,Ordos City from July 18th to 20th with the theme of“Cashmere Chain Links the World,Intelligence Empowers the Future”.
文摘Cultural artifacts exhibitions are among the most profound and appealing forms of cultural exchange.These exhibitions serve as an important bridge for fostering friendly relations between countries and bringing people closer together.
文摘The“Black Myth:Wukong Encounter Shanxi”digital art exhibition opened in Taiyuan,Shanxi Province,on October 31.The show blended Chinese video game Black Myth:Wukong with miniature ancient architecture,highlighting the charm of Shanxi’s heritage.
文摘Recently,SAMR issued four national standards in the exhibition services sector,including the newly developed GB/T 45704-2025,Guidelines for online exhibition services,and three revised standards.GB/T 45704-2025 addresses the emerging online exhibition models.It provides guidelines for the whole exhibition process,and clarifies the requirements for service providers’capabilities,to promote the healthy development of this evolving industry.
文摘The 51st China Beijing International Gifts,Premium and Houseware Exhibition(hereinafter referred to as the Gifts Exhibition) officially opened the kaleidoscope of creative gifts at China International Exhibition Center (Chaoyang Pavilion) on March 20th.More than 900 exhibitors built an aesthetic corridor of quality life with 200,000 gifts.
文摘From August 14 to 16,the 52nd China Beijing International Gifts,Premium&Houseware Exhibition(hereinafter referred to as Beijing Gift&Home)was held at the China International Exhibition Center(Chaoyang Pavilion)in Beijing,China.As the annual grand finale of the northern gift industry.
文摘From June 4 to 17,2025,the Harmony Together for a Friendly Future-Exhibition of Intermitioncil Youth Photography,jointly hosted by China Center of International Cultural Exchange and Tourism Promotion(CETP)nnd China Cultural Center in Copenhagen,was successfully held at the China Cultured Center in Copenhagen.
文摘On March l3th,the three-day Intertextile Shanghai Apparel Fabrics-Spring Edition 2025 concluded successfully at the National Exhibition andConvention Center(Shanghai).This bustling event,carrying the expectationsof the industry,conveyed the enthusiasm for business cooperation in China'stextile industry at the beginning of 2025 through its exhibition data.
文摘From June 4 to 17,2025.the Harmony Together for Friendly future-Exhibition of International Youth Photography.jointly Hosted by China Center for International Culture and Tourism Exchanges(CCICTE) and China Cultural Center in Copenhagen.
