Exercise is one of the preferred management strategies for diabetic patients,but the exercise mode including type,intensity,and duration time is quite different for each patient because of individual differences.Inade...Exercise is one of the preferred management strategies for diabetic patients,but the exercise mode including type,intensity,and duration time is quite different for each patient because of individual differences.Inadequate exercise has no effect on the blood glucose control,while overexercise may cause serious side effects,such as hypoglycemia and loss of blood glucose control.In this work,we report a closed-loop feedback mode for exercise management in diabetes.A minimally invasive,biocompatible microneedle electrode patch was fabricated and used for continuously monitoring the glucose in the interstitial fluid.Further,in conjunction with using a wireless electrochemical device,the glucose signals can be analyzed to output the potency of exercise and give advice on exercise management.A custom exercise given by this closed-loop feedback mode can reduce the used dose of insulin and avoid side effect during and after exercise.We believe that this work can provide a novel comprehensive guidance for diabetic patients.展开更多
Hypoglycemia limits optimal glycemic management of patients with type 1 diabetes mellitus(T1DM).Fear of hypoglycemia(FoH)is a significant psychosocial consequence that negatively impacts the willingness of T1DM patien...Hypoglycemia limits optimal glycemic management of patients with type 1 diabetes mellitus(T1DM).Fear of hypoglycemia(FoH)is a significant psychosocial consequence that negatively impacts the willingness of T1DM patients to engage in and profit from the health benefits of regular physical activity(e.g.,cardiometabolic health,improved body composition,cardiovascular fitness,quality of life).Technological advances,improved insulin regimens,and a better understanding of the physiology of various types of exercise could help ameliorate FoH.This narrative review summarizes the available literature on FoH in children and adults and tools to avoid it.展开更多
基金supported by the National Natural Science Foundation of China(22125405 and 22074131).
文摘Exercise is one of the preferred management strategies for diabetic patients,but the exercise mode including type,intensity,and duration time is quite different for each patient because of individual differences.Inadequate exercise has no effect on the blood glucose control,while overexercise may cause serious side effects,such as hypoglycemia and loss of blood glucose control.In this work,we report a closed-loop feedback mode for exercise management in diabetes.A minimally invasive,biocompatible microneedle electrode patch was fabricated and used for continuously monitoring the glucose in the interstitial fluid.Further,in conjunction with using a wireless electrochemical device,the glucose signals can be analyzed to output the potency of exercise and give advice on exercise management.A custom exercise given by this closed-loop feedback mode can reduce the used dose of insulin and avoid side effect during and after exercise.We believe that this work can provide a novel comprehensive guidance for diabetic patients.
文摘Hypoglycemia limits optimal glycemic management of patients with type 1 diabetes mellitus(T1DM).Fear of hypoglycemia(FoH)is a significant psychosocial consequence that negatively impacts the willingness of T1DM patients to engage in and profit from the health benefits of regular physical activity(e.g.,cardiometabolic health,improved body composition,cardiovascular fitness,quality of life).Technological advances,improved insulin regimens,and a better understanding of the physiology of various types of exercise could help ameliorate FoH.This narrative review summarizes the available literature on FoH in children and adults and tools to avoid it.
