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Evaluation and Characterization of Executive Function Disorders after Stroke
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作者 El Hadji Makhtar Ba Hilaire Dominique Ewodo Touna +16 位作者 Momar Camara Sokhna Seck Bocar Baila Diédhiou Racky Wade Fatoumata Ba Ndèye Awa Dieye Maimouna Dieye Ndiaga Matar Gaye Adjaratou Dieynabou Sow Anna Mbodj Basse Marieme Soda Diop Lala Bouna Seck Ousmane Cisse Khadim Fall Adama Koundoul Mbayang Ndiaye Aida Sylla 《Open Journal of Psychiatry》 2025年第1期16-23,共8页
Introduction: Stroke may have a negative impact on mental health and behavior. Cognitive disorders are common after stroke. They are rarely assessed in current clinical practice, particularly in our context. They cons... Introduction: Stroke may have a negative impact on mental health and behavior. Cognitive disorders are common after stroke. They are rarely assessed in current clinical practice, particularly in our context. They constitute a real “invisible” handicap. In sub-Saharan Africa, we are not aware of any studies specifically assessing executive functions. These functions are at the heart of all adaptation processes to new or complex situations. This prompted the authors to carry out this study at the Ibrahima Pierre Ndiaye Neuroscience Department of the Fann National University Hospital Centre (Senegal). Objective and Methodology: The aim of this study was to assess and characterize post-stroke alterations in executive functions in our context. We conducted a descriptive cross-sectional study. It took place over a 4-month period from April 1 to August 31, 2021. Patients were matched to controls according to age, gender and educational level. Executive functions were assessed using the Frontal Assessment Battery (FAB). Results: A total of 30 patients with stroke were enrolled. These patients were matched to controls. The mean age of the patients was 46.87 ± 17.65 years. For the control group, it was 39.27 ± 12.33 years. The prevalence of executive function disorders was 20% in post-stroke patients. The majority of executive functions assessed were impaired. Sensitivity to interference and environmental autonomy were the only ones preserved. Conclusion: Impaired executive functions are common after stroke. They should be systematically assessed in all stroke patients to ensure optimal management. 展开更多
关键词 POST-STROKE Mental Health executive functions Invisible Disability Senegal
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Parental autonomy support effects on children’s school adjustment:The longitudinal mediating effect of executive function
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作者 Xia Hu Zhu Li +1 位作者 Yawen Shi Xiaopei Xing 《Journal of Psychology in Africa》 2025年第4期471-480,共10页
This longitudinal study examined the association between parental autonomy support and school-aged children’s adjustment across four major domains of school functioning,as well as the mediating role of children’s ex... This longitudinal study examined the association between parental autonomy support and school-aged children’s adjustment across four major domains of school functioning,as well as the mediating role of children’s executive function.Participants were 476 school-aged children(girl:49.2%,M_(age)=10.49 years,SD=1.32 years),who completed the Psychological Autonomy Support Scale,the Behavior Rating Inventory of Executive Function–2,and the Primary School Students’Psychological Suzhi Scale at baseline and at two subsequent follow-up assessments.Results from unconditional latent growth curve models and structural equation modeling indicated that paternal autonomy support was a significant predictor of children’s adjustment across all four school domains.In contrast,maternal autonomy support was significantly associated only with interpersonal adjustment.Both the intercept(initial level)and slope(rate of change)of children’s executive function significantly predicted their adjustment in all four domains.Notably,the initial level of executive function fully mediated the association between paternal autonomy support and school adjustment,whereas the rate of change in executive function did not serve as a significant mediator.Thesefindings underscore the importance of promoting parental autonomy-supportive behaviors-particularly among fathers-as a means to enhance children’s executive functioning and,consequently,their school adjustment. 展开更多
关键词 parental autonomy support executive function school adjustment longitudinal mediation
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The Relationship between Adverse Childhood Experiences and Health Risk Behaviors of Adolescents:The Mediating Role of Executive Function Deficits
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作者 Riza Hayati Ifroh Xiaosong Gai 《International Journal of Mental Health Promotion》 2025年第6期787-807,共21页
Background:Adverse childhood experiences(ACEs)are a significant issue in adolescent health due to their robust correlation with deficits in executive functions(EF)and health risk behaviors(HRBs).This study aimed to ex... Background:Adverse childhood experiences(ACEs)are a significant issue in adolescent health due to their robust correlation with deficits in executive functions(EF)and health risk behaviors(HRBs).This study aimed to examine the association between ACEs and a range of HRBs,including substance use,sexual risk behavior,suicidal ideation,physical inactivity,and violence.Methods:This cross-sectional study used self-administered questionnaire and cluster sampling in seven junior high schools in Samarinda,Indonesia,with a sample size of 534 students.Data analysis using descriptive statistics,the Chi-square test,the independent t-test,ANOVA,binary logistic regression,and mediation analysis with macro-PROCESS.Results:The most common ACEs were community violence(68.0%),physical neglect(52.8%),psychological/emotional abuse(52.6%),physical abuse(50.4%),and peer bullying(45.9%).Adolescents with more than five ACEs showed significantly higher involvement in smoking/vaping(67.9%),suicidal ideation(75.2%),sexual risk behavior(57.7%),bullying(64.3%),and physical fighting(59.7%)(p<0.001).ACEs were significantly correlated with EF deficits(r=0.471,p<0.01)and HRB(r=0.578,p<0.01).Regression analysis confirmed that ACEs predicted EF deficits(β=0.466,p<0.001)and HRB(β=0.469,p<0.001),with EF deficits partially mediating this relationship(β=0.107,95%CI[0.045,0.094]).In addition,two subdomains of EF deficits,self-motivation(β=0.042)and self-regulation of emotion(β=0.032),significantlymediated the relationship between ACEs and HRBs.Conclusion:These findings suggest an important role for EF deficits in linking childhood adversity to engagement in risky behaviors.Addressing ACEs and EF deficits(self-motivation and self-regulation of emotion)through early intervention may be important in reducing long-term health risks among Indonesian adolescents. 展开更多
关键词 Adverse childhood experience executive function health risk behaviors adolescent development
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Bibliographical Review on Rehabilitation of Executive Functions in Patients With Developmental Coordination Disorder(DCD)
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作者 Keiko da Costa Oikawa Fabrício Bruno Cardoso +3 位作者 Filipe M.Bonone Samuel Pereira de Souza Vitor da Silva Loureiro Alfred Sholl-Franco 《Psychology Research》 2024年第2期45-56,共12页
The present study aims to establish a literature review on intervention programs for executive functions(EFs)through the use of fundamental motor skills,from a neuropsychopedagogical perspective in subjects with Devel... The present study aims to establish a literature review on intervention programs for executive functions(EFs)through the use of fundamental motor skills,from a neuropsychopedagogical perspective in subjects with Developmental Coordination Disorder(DCD).An exploratory study was carried out through an integrative literature review.The research was carried out in the Scientific databases Electronic Library Online(SciELO),Latin American and Caribbean Literature in Health Sciences(LILACS),Virtual Health Library-Psychology Brazil(BVSPSI),Electronic Journals of Psychology(PePSIC),in the periodicals available in the Brazilian Digital Library of Theses and Dissertations(BDTD)and on the website of the Coordination for the Improvement of Higher Education Personnel(CAPES).The covering publications took place from 2018 to 2023,14 articles were selected for analysis.This literature review made it possible to create strategies for stimulating EF and Visuomotor Functions so that educators and other professionals can better deal with students with DCD.It was perceived the need to carry out and develop more empirical research regarding the intervention of EFs and Visuomotor Functions by educators and professionals,with a greater sampling amplitude,to increase the number of studies that enable interventions both in children and in teenagers with DCD. 展开更多
关键词 developmental coordination disorder executive functions school neuropsychology stimulation of executive functions
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Acute exercise is associated with specific executive functions in college students with ADHD:A preliminary study 被引量:10
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作者 Jennifer I.Gapin Jeffrey D.Labban +2 位作者 Sara C.Bohall Joshua S.Wooten Yu-Kai Chang 《Journal of Sport and Health Science》 SCIE 2015年第1期89-96,共8页
Purpose: The relationship between acute exercise and executive functions in college students with attention deficit hyperactivity disorder (ADHD) has not been clearly established. The purpose of this preliminary st... Purpose: The relationship between acute exercise and executive functions in college students with attention deficit hyperactivity disorder (ADHD) has not been clearly established. The purpose of this preliminary study was to examine the difference in cognitive performance between college students with and without ADHD and to explore the effects of acute exercise on multiple aspects of executive functions and on serum brain derived neurotrophic factor (BDNF). Methods: College students (normal: n = 10; ADHD: n = 10) performed the Stroop Test, Trail Making Test, and Digit Span Test prior to and after an acute exercise intervention. Blood samples were obtained prior to the pre-test cognitive test performance and then again after exercise and prior to the post-test cognitive test performance. Results: Students with ADHD exhibited impaired executive functions, particularly on inhibition. Additionally, while acute exercise improved all aspects of executive functions in those without ADHD, acute exercise only improved inhibitory performance for those with ADHD. Further, BDNF was not influenced by acute exercise regardless of the subjects' ADHD status. Conclusion: These results provide preliminary evidence for exercise as a potential adjunct treatment for benefitting inhibition in college students with ADHD. 展开更多
关键词 COGNITION executive function NEUROTROPHINS Physical activity
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Processing Environmental Stimuli in Paranoid Schizophrenia:Recognizing Facial Emotions and Performing Executive Functions 被引量:4
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作者 YU Shao Hua ZHU Jun Peng +6 位作者 XU You ZHENG Lei Lei CHAI Hao HE Wei LIU Wei Bo LI Hui Chun WANG Wei 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2012年第6期697-705,共9页
Objective To study the contribution of executive function to abnormal recognition of facia expressions of emotion in schizophrenia patients. Methods Abnormal recognition of facial expressions of emotion was assayed ac... Objective To study the contribution of executive function to abnormal recognition of facia expressions of emotion in schizophrenia patients. Methods Abnormal recognition of facial expressions of emotion was assayed according to Japanese and Caucasian facial expressions of emotion (JACFEE), Wisconsin card sorting test {WCST), positive and negative symptom scale, and Hamilton anxiety and depression scale, respectively, in 88 paranoid schizophrenia patients and 75 healthy volunteers. Results Patients scored higher on the Positive and Negative Symptom Scale and the Hamilton Anxiety and Depression Scales, displayed lower JACFEE recognition accuracies and poorer WCST performances. The JACFEE recognition accuracy of contempt and disgust was negatively correlated with the negative symptom scale score while the recognition accuracy of fear was positively with the positive symptom scale score and the recognition accuracy of surprise was negatively with the general psychopathology score in patients. Moreover, the WCST could predict the JACFEE recognition accuracy of contempt, disgust, and sadness in patients, and the perseverative errors negatively predicted the recognition accuracy of sadness in healthy volunteers. The JACFEE recognition accuracy of sadness could predict the WCST categories in paranoid schizophrenia patients. Conclusion Recognition accuracy of social-/moral emotions, such as contempt, disgust and sadness is related to the executive function in paranoid schizophrenia patients, especially when regarding sadness. 展开更多
关键词 executive function Japanese and Caucasian facial expressions of emotion Paranoidschizophrenia Wisconsin card sorting test
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Executive functioning in TBI from rehabilitation to social reintegration: COMPASS^(goal), a randomized controlled trial(grant: 1I01RX000637-01A3 by the VA ORD RR&D, 2013–2016) 被引量:1
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作者 Alexander V.Libin Joel Scholten +11 位作者 Manon Maitland Schladen Ellen Danford Nawar Shara Walter Penk Jordan Grafman Linda Resnik Dwan Bruner Samantha Cichon Miriam Philmon Brenda Tsai Marc Blackman Alexander Dromerick 《Military Medical Research》 SCIE CAS 2015年第4期181-200,共20页
Background: Traumatic brain injury is a major health problem that frequently leads to deficits in executive function. Self-regulation processes, such as goal-setting, may become disordered after traumatic brain injury... Background: Traumatic brain injury is a major health problem that frequently leads to deficits in executive function. Self-regulation processes, such as goal-setting, may become disordered after traumatic brain injury, particularly when the frontal regions of the brain and their connections are involved. Such impairments reduce injured veterans' ability to return to work or school and to regain satisfactory personal lives. Understanding the neurologically disabling effects of brain injury on executive function is necessary for both the accurate diagnosis of impairment and the individual tailoring of rehabilitation processes to help returning service members recover independent function.Methods/design: The COMPASSgoal(Community Participation through Self-Efficacy Skills Development) program develops and tests a novel patient-centered intervention framework for community reintegration psychosocial research in veterans with mild traumatic brain injury. COMPASSgoal integrates the principles and best practices of goal self-management. Goal setting is a core skill in self-management training by which persons with chronic health conditions learn to improve their status and decrease symptom effects. Over a three-year period, COMPASSgoal will recruit 110 participants with residual executive dysfunction three months or more post-injury. Inclusion criteria combine both clinical diagnosis and standardized scores that are >1 SD from the normative score on the Frontal Systems Rating Scale. Participants are randomized into two groups: goal-management(intervention) and supported discharge(control). The intervention is administered in eight consecutive, weekly sessions. Assessments occur at enrollment, post-intervention/supported discharge, and three months post-treatment follow-up.Discussion: Goal management is part of the "natural language" of rehabilitation. However, collaborative goal-setting between clinicians/case managers and clients can be hindered by the cognitive deficits that follow brain injury. Re-training returning veterans with brain injury in goal management, with appropriate help and support, would essentially treat deficits in executive function. A structured approach to goal self-management may foster greater independence and self-efficacy, help veterans gain insight into goals that are realistic for them at a given time, and help clinicians and veterans to work more effectively as true collaborators. 展开更多
关键词 executive function Traumatic brain injury GOAL-SETTING Community reintegration VETERANS Randomized controlled trial Manualized psychosocial intervention
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Association between central obesity and executive function as assessed by stroop task performance:A functional near-infrared spectroscopy study 被引量:1
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作者 Zhangyan Deng Qin Huang +3 位作者 Jiaai Huang Weixia Zhang Changzhu Qi Xia Xu 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2018年第1期37-46,共10页
Recent studies have suggested a link between executive function(EF)and obesity.Studies oftenadopt body mass index(BM),which reflects the distribution of subcutaneous fat,as the solemarker of obesity;however,BMI is ina... Recent studies have suggested a link between executive function(EF)and obesity.Studies oftenadopt body mass index(BM),which reflects the distribution of subcutaneous fat,as the solemarker of obesity;however,BMI is inappropriate to distinguish central obesity,which indicatesthe centralized distribution of visceral fat.Visceral fat compared with subcutaneous fat repre-sents greater relative lipid turnover and may increase the risk of cognitive decline in older adults.However,the relationship between EF and central obesity is largely unknown,particularly inyoung adults.Therefore,we used waist circumference(WC)as a marker of central obesity andinvestigated diferent sensitivities between BMI and WC in the brain function.A total of 26healthy young adults(aged 18-25 years;42%female)underwent functional near-infrared spec-troscopy assessments.EF was assessed using the Stroop task,which is a classical measurementof EF.A significant Stroop effect was observed in the behavioral and hemodynamic data.Inaddition,we observed that behavioral interference on the Stroop task varied much more insubjects with higher BMI and WC than those subjects with lower.Elevated BMI and WC wereassociated with a decreased hemodynamic response during the Stroop task specifically in the pre-frontal cortex(PFC).Compared to BMI,WC was more closely connected with inhibitory controland revealed right lateralized PFC activation.Our findings suggest that WC is a reliable indicatorof brain function in young adults and propose a relationship bet ween EF and central obesity. 展开更多
关键词 executive function central obesity FNIRS young adult
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Impact of Auditory-Verbal Therapy on executive functions in children with Cochlear Implants 被引量:1
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作者 Mohammad Ashori 《Journal of Otology》 CSCD 2022年第3期130-135,共6页
Objective: Auditory-Verbal Therapy(AVT) can be considered one of the best practices for children with Cochlear Implants(CIs) who show impairments in cognitive skills such as executive functions. Hence,this research ex... Objective: Auditory-Verbal Therapy(AVT) can be considered one of the best practices for children with Cochlear Implants(CIs) who show impairments in cognitive skills such as executive functions. Hence,this research examined the impact of AVT on the executive functions in children with CIs.Methods: This was a randomized case control study with pre-and post-intervention assessments. The participants were 36 children with CIs and their mothers. They were randomly selected from rehabilitation centers and deaf pre-schools, and randomly allocated to a control(n = 18) and a study(n = 18)group. The mean age of the children in the study and control groups was 3.11 ± 0.31 years and 3.20 ± 0.29years, respectively. Participants in the study group received 20 sessions of AVT over 10 weeks at twice a week, while those in the control group did not. All mothers completed the Behavior Rating Inventory of Executive Function Pre-school Version(BRIEF-P) before and after children in the study group completed their AVT intervention. Data were analyzed by MANCOVA.Results: The results suggest that AVT significantly influenced executive functions and all subscales including shifting, inhibition, emotional control, working memory and organization/planning in children with CIs.Conclusions: These findings suggest that AVT may be effective in resulting in positive outcomes and may play an important role in improving executive functions in children with CIs. 展开更多
关键词 Auditory-verbal therapy Early intervention executive functions
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Effectiveness of Mindfulness Training in Enhancing Executive Function and Decreasing Symptoms of Depression and Anxiety in Patients with Multiple Sclerosis (MS) 被引量:1
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作者 Mahsa Amiri Mehdi Rabiei Vahid Donyavi 《Journal of Behavioral and Brain Science》 2016年第8期329-336,共8页
The purpose of the present study was to evaluate the effectiveness of mindfulness training in enhancing executive function and decreasing symptoms of depression and anxiety in multiple sclerosis patients. The populati... The purpose of the present study was to evaluate the effectiveness of mindfulness training in enhancing executive function and decreasing symptoms of depression and anxiety in multiple sclerosis patients. The population in this study consisted of people with MS who referred to Karaj city MS society in 1394. These people didn’t experience medicinal changes during the study period and their expanded disability status score (EDSS) was between 0 and 5.5. 40 of them were randomly selected and placed into two experimental and control groups (20 for the experimental and the other for the control group). The treatment of mindfulness training was held in 8 sessions of group training, once a week and for 2 hours. The statistical method of multivariate analysis of covariance was used. The measurement tools were the State-Trait Anxiety Inventory (STAI), the Beck Depression Inventory-II (BDI-II) and the Wisconsin Card Sorting Test (WCST). After all, the results in both groups were compared and evaluated by the use of analysis of covariance. The results showed significant differences in symptoms of anxiety and depression between the two groups (p 0.05). Generally, the results of this research showed positive effects of mindfulness training on reducing anxiety and depression among patients with MS and ineffectiveness of mindfulness training on their executive function. Therefore, considering that there is no certain treatment for MS plus results of this study, the application of mindfulness training can be quite useful to reduce levels of anxiety and depression in patients with MS. 展开更多
关键词 MINDFULNESS executive function DEPRESSION ANXIETY Multiple Sclerosis Patients
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Assessment of Stress Cognitive Control and Executive Function with Stress Control Rating Scale (ECOSTRESS) and Low Resolution Brain Electromagnetic Tomography (LORETA) (In Portuguese People in Situations of Unemployment and Economic Insufficiency) 被引量:1
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作者 Eduardo Gonçalves Marco Moniz Saul Neves Jesus 《Open Journal of Psychiatry》 2016年第2期158-164,共7页
This article reviews the constructs of stress, appraisal, coping, according to a transactional perspective, and executive function, and presents a stress control rating scale (ECOSTRESS), which design is founded in th... This article reviews the constructs of stress, appraisal, coping, according to a transactional perspective, and executive function, and presents a stress control rating scale (ECOSTRESS), which design is founded in these constructs. This psychometric tool is useful in the assessment of cognitive control of stress, correlated with the function of dorsolateral prefrontal cortex. It has been validated for its use in the assessment of Portuguese people in situations of stress related to unemployment and economic insufficiency. Also, within the context of the cognitive control of stress, it is highlighted the usefulness of low resolution brain electromagnetic tomography (LORETA). 展开更多
关键词 Stress Anxiety Depression MANIA Economic Insufficiency executive function Anterior Cingulate Cortex Dorsolateral Prefrontal Cortex Stress Control Rating Scale (ECOSTRESS) Low Resolution Brain Electromagnetic Tomography (LORETA) NEUROFEEDBACK
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Failure to identify an acute exercise effect on executive function assessed by the Wisconsin Card Sorting Test
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作者 Chun-Chih Wang Chia-Hao Shih +3 位作者 Caterina Pesce Tai-Fen Song Tsung-Min Hung Yu-Kai Chang 《Journal of Sport and Health Science》 SCIE 2015年第1期64-72,共9页
Purpose: Acute exercise has been linked to the facilitation of executive function, but little is known regarding executive function assessed by the Wisconsin Card Sorting Test (WCST). The present research consisted... Purpose: Acute exercise has been linked to the facilitation of executive function, but little is known regarding executive function assessed by the Wisconsin Card Sorting Test (WCST). The present research consisted of two experiments aimed to determine whether acute aerobic exercise influences successive WCST performance. Methods: In Study 1, 27 young adults were randomly assigned to the exercise or reading control group and then instiucted to perform the WCST before and after assigned treatment. In exercise group, participants completed a single bout aerobic exercise with moderate intensity for 20 min on a stationary bike. A similar experimental protocol was replicated in Study 2 with 24 late middle-aged adults to look for age differences during adulthood and control for a potential ceiling effect at young adult age. Results: Although a significant time effect was observed in young adults, both studies revealed that there was no main effect for treatment or an interaction between treatment and time on any of the WCST indices. Conclusion: Acute aerobic exercise failed to influence executive function as assessed by the WCST, revealing that this classical neuropsy- chological test tapping executive function may not be sensitive to acute exercise. Our findings suggest that acute exercise does not broadly affect the entire family of executive functions, or its effect on a specific aspect of executive function may be task-dependent, as proposed by Etnier and Chanj~ (2009). 展开更多
关键词 Aerobic exercise Cognitive control executive function Neuropsychological assessment
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Optical neuroimaging of executive function impairments in food addiction
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作者 Tania Alexandra Couto Meng-Yun Wang Zhen Yuan 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2022年第1期141-155,共15页
This study investigated the neural mechanisms located in the prefrontal cortex(PFC)involved in maintaining addictive-like eating behavior.Therefore,we aimed toll a gap in the existing literature and help clarify the f... This study investigated the neural mechanisms located in the prefrontal cortex(PFC)involved in maintaining addictive-like eating behavior.Therefore,we aimed toll a gap in the existing literature and help clarify the food addiction(FA)cycle by inspecting the relationship between the executive control and psychopathology involved in the FA cycle.Twenty-three students recruited from the University of Macao participated in this study.We investigated a hemodynamic response captured by NIRS recordings,activated during n-back,set-shifting,and go/nogo paradigms.Moreover,we investigated the FA symptoms through the YFAS clinical inventory to better understand the relationship between hemodynamic response and clinical symptomatology in college students.First,the hemodynamicndings conrm that altered cognitive control in executive function performance appears to be linked to addictive-like eating behaviors,which in turn conrms a circuit similarity between FA and the substance abuse population(SUD)as reported in previous fMRI studies.Secondly,the psychologicalndings conrm the signicant association between the working memory decits and symptoms severity which suggest the role of self-control and regulation in limiting the storage resources as a potential trigger to develop overconsumption episodes in the FA cycle.Ourndings highlight how disrupted self-control and regulation of craving and negative a®ect induced by mental imagery might shape and overload the working memory storage as a potential trigger to develop binge eating episodes to maintain the FA cycle.In conclusion,the use of fNIRS in the context of eating disorders studies represents a valuable application,noninvasive,and patientfriendly tool,providing new insights into understanding the addiction cycle and treatment guidelines. 展开更多
关键词 Food addiction executive functions working memory SELF-CONTROL optical neuroimaging.
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Apolipoprotein E gene polymorphisms associated with processing speed and executive functions in healthy Han Chinese
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作者 Cheng-Cheng Zhang H ong-Yan Ren +9 位作者 Ming-LiLi Qiang Wang Wei Deng Wan-Jun Guo Wei Lei Bo Xiang Lian-Sheng Zhao Xiao-Hong Ma Yong-Gang Yao Tao Li 《Neuroscience Bulletin》 SCIE CAS CSCD 2015年第3期368-370,共3页
Dear Editor,A few studies have focused on exploring APOE gene- related effects on cognitive functions and brain activities in healthy populations. Bondi et aL found that ε4 carriers perform significantly worse on the... Dear Editor,A few studies have focused on exploring APOE gene- related effects on cognitive functions and brain activities in healthy populations. Bondi et aL found that ε4 carriers perform significantly worse on the California Verbal Learning Test than non-carriers in non-demented old subjects (mean age, 72 years)ε11. But the results are not entirely consistent. For example, Scarmeas et aL found no effect of the E4 allele on neuropsychological performance[2] in young adults, and Jochemsen et al. found that the ε4 allele is associated with age-related cognitive decline[3]. Furthermore, protective and negative effects of the E2 allele on cognition are inconsistent[4' s]. APOE E2 is thought to be a protective allele for AD in the elderly population due to its role in the superior cognitive performance of ε2 carriers compared to E3 or E4 carriers[5]. However, the ε2 allele has also been found to have a negative effect on AD pathology[4]. 展开更多
关键词 Apolipoprotein E gene polymorphisms associated with processing speed and executive functions in healthy Han Chinese GENE
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Topographical Analysis of Frontal Lobe Executive Functions in Patients Following a Stroke
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作者 Roberta Márcia Torres Kristiana Cerqueira Mousinho +6 位作者 Liércio Pinheiro Nathália Costa Toledo Pacheco Piatti Taise Almeida Cavalcante Aline da Silva Amorim Ana Karolina Barros de Jesus Maria Wylianna Oliveira dos Santos Euclides Maurício Trindade Filho 《World Journal of Neuroscience》 2016年第2期143-150,共8页
Objective: This study aimed to carry out a topographical analysis of frontal lobe executive function components in post-stroke patients. Methods: A descriptive, cross-sectional study. The assessment using the WCST (Wi... Objective: This study aimed to carry out a topographical analysis of frontal lobe executive function components in post-stroke patients. Methods: A descriptive, cross-sectional study. The assessment using the WCST (Wisconsin Card Sorting Test) included sixteen patients with a clinical diagnosis of CVA and frontal lobe impairment. Results from the two groups were compared (patients with right frontal lobe impairment and patients with left frontal lobe impairment). Statistical analysis was performed using the program “Statistical Package for Social Sciences” (SPSS) Version 20.0. For comparison between groups was used Mann-Whitney test and considered the alpha level of 0.05 on the statistically significant results. Results: There was no statistically significant difference between the groups, thus showing that executive functions are symmetrically distributed across the frontal lobes. Conclusion: Executive functions are symmetrically organized across the two frontal lobes, since the comparison between the groups did not demonstrate a statistically significant difference for any of the variables of WSCT. 展开更多
关键词 executive function STROKE Frontal Lobe NEUROPSYCHOLOGY
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Basic Study Impact of stimulant medication on behaviour and executive functions in children with attention-deficit/hyperactivity disorder
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作者 Tasmia Hai Hanna A Duffy +1 位作者 Julie Anne Lemay Jean François Lemay 《World Journal of Clinical Pediatrics》 2022年第1期48-60,共13页
BACKGROUND Children with attention-deficit/hyperactivity disorder(ADHD)often exhibit behaviour challenges and deficits in executive functions(EF).Psychostimulant medications[e.g.,methylphenidate(MPH)]are commonly pres... BACKGROUND Children with attention-deficit/hyperactivity disorder(ADHD)often exhibit behaviour challenges and deficits in executive functions(EF).Psychostimulant medications[e.g.,methylphenidate(MPH)]are commonly prescribed for children with ADHD and are considered effective in 70%of the cases.Furthermore,only a handful of studies have investigated the long-term impact of MPH medication on EF and behaviour.AIM To evaluate behaviour and EF challenges in children with ADHD who were involved in an MPH treatment trial across three-time points.METHODS Thirty-seven children with ADHD completed a stimulant medication trial to study the short-and long-term impact of medication.Children with ADHD completed three neuropsychological assessments[Continuous Performance Test(CPT)-II,Digit Span Backwards and Spatial Span Backwards].Parents of children with ADHD completed behaviour rating scales[Behaviour Rating Inventory of Executive Functioning(BRIEF)and Behaviour Assessment System for Children-Second Edition(BASC-2)].Participants were evaluated at:(1)Baseline(no medication);and(2)Best-dose(BD;following four-week MPH treatment).Additionally,18 participants returned for a long-term naturalistic follow up(FU;up to two years following BD).RESULTS Repeated measure analyses of variance found significant effects of time on two subscales of BRIEF and four subscales of BASC-2.Neuropsychological assessments showed some improvement,but not on all tasks following the medication trial.These improvements did not sustain at FU,with increases in EF and behaviour challenges,and a decline in performance on the CPT-II task being observed.CONCLUSION Parents of children with ADHD reported improvements in EF and behaviours during the MPH trial but were not sustained at FU.Combining screening tools and neuropsychological assessments may be useful for monitoring medication responses. 展开更多
关键词 Attention-deficit/hyperactive disorder BEHAVIOUR executive functions Stimulant medications
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Stress, Executive Function, Resilience and Quality of Life in Portuguese Subjects in Situations of Economic Insufficiency and Unemployment
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作者 Eduardo Goncalves Saul Neves de Jesus 《Open Journal of Psychiatry》 2015年第4期350-361,共12页
The aim of this study is the investigation of the impact of stress of Portuguese subjects in situations of economic insufficiency and unemployment on executive function and quality of life and the coping strategies an... The aim of this study is the investigation of the impact of stress of Portuguese subjects in situations of economic insufficiency and unemployment on executive function and quality of life and the coping strategies and resilience skills used. The sample consists of 41 participants. The psychometric instruments used are validated for Portuguese population, measure (perceived) stress, coping, material deprivation, resilience and quality of life, defined by World Health Organization. Executive function has been evaluated through performances at Stroop and Berg tasks. It has been concluded that, in this population, resilience skills and active coping strategies are positively correlated with quality of life. Quality of life is negatively correlated with material deprivation. Active coping strategies are supported by adequate executive function, which neurobiological substrate is dorso-lateral prefrontal cortex. Not active coping strategies correlate negatively with cognitive flexibility, suggesting the presence of a deficit at infero-lateral prefrontal cortex. 展开更多
关键词 STRESS Economic Insufficiency UNEMPLOYMENT Coping RESILIENCE Quality of Life executive function
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Neuropsychological Rehabilitation of Executive Functions: Challenges and Perspectives
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作者 Priscila Dib Goncalves Mariella Ometto +3 位作者 Gabriela Sendoya Cristine Lacet Luciana Monteiro Paulo Jannuzzi Cunha 《Journal of Behavioral and Brain Science》 2014年第1期27-32,共6页
Introduction: Executive Dysfunction (ED) is associated with difficulties in daily life and poor treatment adherence in individuals with neurological and psychiatric disorders. The aim of this paper is to present an up... Introduction: Executive Dysfunction (ED) is associated with difficulties in daily life and poor treatment adherence in individuals with neurological and psychiatric disorders. The aim of this paper is to present an update of Executive Function (EF) Rehabilitation Techniques. Methods: We performed a comprehensive literature review using the following keywords: executive function, mental disorders and rehabilitation in the PubMed, specific journals and books. Results: There is evidence of improvement of EF using some rehabilitation techniques, such as goal planning, goal management training, problem solving training, verbalization, drill and practice approach, metacognitive strategy instruction, computer-assisted training and neurofeedback. However, impact of rehabilitation on daily life remains poorly understood. Conclusion: Executive Dysfunction (ED) may be remediated and/or compensated at a certain degree by neuropsychological rehabilitation, but there is still a great challenge in this area based on how to measure effectiveness of EF interventions on daily life. There is a need for the development of new and/or combined techniques (i.e., pharmacological treatment, deep-brain stimulation) for a broader impact on quality of life for patients. 展开更多
关键词 REHABILITATION NEUROPSYCHOLOGY executive functions Board Games
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Effects of Pre-Class Acute Exercise on Executive Function in University Students
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作者 Weijia Zhu Linjing Zhou +21 位作者 Zijun Liu Kaiqi Guan Yifei Dong Meijun Hou Xun Luo Ziquan Cai Jinming Li Zhihao Zhang Qian Yu Sebastian Ludyga Tai Ji Jiahui Wang Ryan SFalck Charles HHillman Kirk IErickson Arthur FKramer Mats Hallgren Myrto FMavilidi Fred Paas Matthew Heath Fabian Herold Liye Zou 《International Journal of Mental Health Promotion》 2025年第10期1439-1455,共17页
Background:There is growing evidence that an acute bout of exercise positively influences executive function(EF).However,the existing evidence primarily originates from laboratory-based studies,and only a limited numb... Background:There is growing evidence that an acute bout of exercise positively influences executive function(EF).However,the existing evidence primarily originates from laboratory-based studies,and only a limited number of studies have extended this work to real-world classroom settings.Accordingly,in the present study,we aimed to employ a real classroom setting to determine whether acute exercise-induced effects on EF emerged.Methods:All 49 students who enrolled in a real-world course agreed to participate in the experimental protocol and the final sample was composed of 43 individuals(13 male and 30 female participants).Participants were asked to perform an acute bout of exercise(i.e,10 min at moderate intensity)before a real classroom,and on a separate day,complete a non-exercise control condition.EF was assessed via Naming,Inhibition,and Switching variants of the Stroop task.We used a paired-samples t-test to compare participants’cognitive load between two conditions and a repeated-measures ANOVA to investigate changes in RPE.What’s more,a repeated measures ANOVA was used to examine potential pre-to post-class changes in EF-related parameters(e.g.,inverse efficiency scores,reaction times,and error rates).Results:A pre-to post-class benefit in performance efficiency across all Stroop task variants was shown.In both exercise and control conditions,there was a significant main effect of time,with lower inverse efficiency scores(IES)(p=0.003)and shorter reaction times(RT)(p<0.001)observed from pre-to post-class.Moreover,performance gains varied by Stroop task-type,with the Switching task showing the longest RTs and largest IES,reflecting its greater cognitive demands.Importantly,a marginally significant three-way interaction among task-type,intervention,and time(p=0.052)indicated that the exercise intervention enhanced post-class performance on the Switching task.Post-hoc analyses revealed significantly lower IES and faster RTs at post-class for both the Naming and Switching tasks,particularly in the exercise group(e.g.,Switching IES:p<0.001;Switching RT:p<0.001).Conclusions:These findings suggest that pre-class acute exercise enhances EF and provides a benefit to cognitive flexibility.Accordingly,our results extend previous knowledge by indicating that the cognitive benefits of acute exercise observed primarily in laboratory settings can be translated to real-world educational contexts. 展开更多
关键词 Physical activity executive function college students class-based sedentary behaviors
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The Relationships between Executive Function and Problem Behavior of Preschool Children:Contextual Specificity and Gender Differences
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作者 BAI Rong YAN Rong +2 位作者 WANG Qian LI Ye XING Shufen 《Frontiers of Education in China》 2024年第2期119-137,共19页
This study utilized a longitudinal design to examine the relationships between the specific components of executive function(EF)and the internalizing and externalizing behavior across different genders and contexts in... This study utilized a longitudinal design to examine the relationships between the specific components of executive function(EF)and the internalizing and externalizing behavior across different genders and contexts in Chinese cultural background.Inhibition,cognitive flexibility,and working memory of EF based on 101 preschool children’s(48 boys and 53 girls)(M_(T1)=4.25,SD=0.76)performances were measured when completing tasks in NIH Toolbox.Twelve months later,boys’and girls’internalizing and externalizing behavior in home-and school-settings was assessed through mother’s feedback on the Strengths and Difficulties Questionnaire and teachers’reports of the Child Behavior Rating Scale.The results show that boys’inhibition,cognitive flexibility,and working memory negatively predict their externalizing behavior in the home context,while their cognitive flexibility negatively predicts externalizing behavior in the school context.Additionally,boys’inhibition positively predicts their internalizing behavior only in the school context.For girls,their cognitive flexibility positively predicts externalizing behavior only in the school context.No significant relationship is found among the girls between EF and problem behavior in the home context.These findings suggest that gender differences and a shift in contexts could alternate the relationship between EF and children’s problem behavior.This study sheds light on targeted preventions and interventions based on contexts and gender. 展开更多
关键词 executive function(EF) problem behavior contextual specificity gender differences preschool children
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