Background:To evaluate the feasibility and safety of a novel cable-transmitted magnetically controlled capsule endoscopy(CTMCE)system for upper gastrointestinal examination.Methods:Twenty-six participants(19 healthy v...Background:To evaluate the feasibility and safety of a novel cable-transmitted magnetically controlled capsule endoscopy(CTMCE)system for upper gastrointestinal examination.Methods:Twenty-six participants(19 healthy volunteers and seven patients with gastrointestinal symptoms)willing to undergo upper gastrointestinal endoscopy were recruited.Each participant underwent CT-MCE followed by conventional gastroscopy within 24 h.Maneuverability and visibility of the CT-MCE capsule in the upper gastrointestinal tract,adverse events,and discomfort during the procedure were evaluated.The sensitivity and specificity of CT-MCE for diagnosing upper gastrointestinal lesions were evaluated using conventional gastroscopy findings as the standard.Results:Maneuverability was graded as“good”for all segments of the esophagus.The percentage of participants in which maneuverability was good according to gastric region was as follows:cardia(100.00%),pylorus(96.15%),angulus(92.31%),antrum(88.46%),fundus(84.62%),and body(73.08%).In the duodenal bulb and descending duodenum,it was good in only 20.83% and 16.67% of participants,respectively.Visibility was graded as“excellent”or“good”in the esophagus,Z line,and duodenal bulb in all participants;excellent/good visibility was achieved in the stomach and descending duodenum in 96.15% and 79.17% of participants,respectively.Forty-one lesions were detected overall.The sensitivity and specificity of CT-MCE in diagnosing upper gastrointestinal lesions were 85.00% and 98.15%,respectively.The CT-MCE capsule was successfully removed through the mouth in all participants.No serious adverse events or capsule retention occurred.Conclusions:CT-MCE showed good feasibility and safety for upper gastrointestinal examination.The system was effective in examining the esophagus and stomach with no risk of capsule retention.展开更多
目的观察浮针疗法对老年患者全膝关节置换术(total knee arthroplasty,TKA)后早期康复及股直肌超声剪切波弹性成像指标的影响。方法纳入膝关节骨性关节炎(knee osteoarthritis,KOA)拟行TKA手术患者64例,按照随机数字表法分为治疗组(32例...目的观察浮针疗法对老年患者全膝关节置换术(total knee arthroplasty,TKA)后早期康复及股直肌超声剪切波弹性成像指标的影响。方法纳入膝关节骨性关节炎(knee osteoarthritis,KOA)拟行TKA手术患者64例,按照随机数字表法分为治疗组(32例)和对照组(32例)。两组均接受标准的围手术期治疗和康复运动,治疗组另予浮针疗法治疗。观察两组围术期膝关节疼痛视觉模拟量表(visual analog scale,VAS)评分、膝关节屈曲角度、美国特种外科医院(hospital for special surgery,HSS)评分、超声剪切波弹性成像指标(股直肌厚度、股直肌横截面积和剪切波速度)、血清C反应蛋白(C-reactive protein,CRP)水平。结果与对照组比较,治疗组术后静息及运动VAS评分均显著降低(P<0.05),且改善趋势更明显(交互效应P<0.05)。治疗组术后第1、3、5天膝关节屈曲角度和HSS评分均优于对照组(P<0.05)。超声弹性成像显示,术后第5天,治疗组发力状态下股直肌横截面积和剪切波速度较对照组提高(P<0.05),放松状态下股直肌厚度亦较对照组增加(P<0.05)。治疗组术后肌力恢复更快(P<0.05),术后第3、5天血清CRP水平低于对照组(P<0.05)。结论在围手术期治疗和康复运动基础上,浮针疗法治疗可有效缓解TKA患者术后早期疼痛,改善膝关节屈曲角度,提高股四头肌肌肉力量,从而改善膝关节功能,且促进炎性吸收。展开更多
基金supported by the National Key Research and Development Program(2019YFC0120303)and was sponsored by the Beijing Nova Program(20240484678).
文摘Background:To evaluate the feasibility and safety of a novel cable-transmitted magnetically controlled capsule endoscopy(CTMCE)system for upper gastrointestinal examination.Methods:Twenty-six participants(19 healthy volunteers and seven patients with gastrointestinal symptoms)willing to undergo upper gastrointestinal endoscopy were recruited.Each participant underwent CT-MCE followed by conventional gastroscopy within 24 h.Maneuverability and visibility of the CT-MCE capsule in the upper gastrointestinal tract,adverse events,and discomfort during the procedure were evaluated.The sensitivity and specificity of CT-MCE for diagnosing upper gastrointestinal lesions were evaluated using conventional gastroscopy findings as the standard.Results:Maneuverability was graded as“good”for all segments of the esophagus.The percentage of participants in which maneuverability was good according to gastric region was as follows:cardia(100.00%),pylorus(96.15%),angulus(92.31%),antrum(88.46%),fundus(84.62%),and body(73.08%).In the duodenal bulb and descending duodenum,it was good in only 20.83% and 16.67% of participants,respectively.Visibility was graded as“excellent”or“good”in the esophagus,Z line,and duodenal bulb in all participants;excellent/good visibility was achieved in the stomach and descending duodenum in 96.15% and 79.17% of participants,respectively.Forty-one lesions were detected overall.The sensitivity and specificity of CT-MCE in diagnosing upper gastrointestinal lesions were 85.00% and 98.15%,respectively.The CT-MCE capsule was successfully removed through the mouth in all participants.No serious adverse events or capsule retention occurred.Conclusions:CT-MCE showed good feasibility and safety for upper gastrointestinal examination.The system was effective in examining the esophagus and stomach with no risk of capsule retention.
文摘目的观察浮针疗法对老年患者全膝关节置换术(total knee arthroplasty,TKA)后早期康复及股直肌超声剪切波弹性成像指标的影响。方法纳入膝关节骨性关节炎(knee osteoarthritis,KOA)拟行TKA手术患者64例,按照随机数字表法分为治疗组(32例)和对照组(32例)。两组均接受标准的围手术期治疗和康复运动,治疗组另予浮针疗法治疗。观察两组围术期膝关节疼痛视觉模拟量表(visual analog scale,VAS)评分、膝关节屈曲角度、美国特种外科医院(hospital for special surgery,HSS)评分、超声剪切波弹性成像指标(股直肌厚度、股直肌横截面积和剪切波速度)、血清C反应蛋白(C-reactive protein,CRP)水平。结果与对照组比较,治疗组术后静息及运动VAS评分均显著降低(P<0.05),且改善趋势更明显(交互效应P<0.05)。治疗组术后第1、3、5天膝关节屈曲角度和HSS评分均优于对照组(P<0.05)。超声弹性成像显示,术后第5天,治疗组发力状态下股直肌横截面积和剪切波速度较对照组提高(P<0.05),放松状态下股直肌厚度亦较对照组增加(P<0.05)。治疗组术后肌力恢复更快(P<0.05),术后第3、5天血清CRP水平低于对照组(P<0.05)。结论在围手术期治疗和康复运动基础上,浮针疗法治疗可有效缓解TKA患者术后早期疼痛,改善膝关节屈曲角度,提高股四头肌肌肉力量,从而改善膝关节功能,且促进炎性吸收。
