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Riemann Hypothesis, Catholic Information and Potential of Events with New Techniques for Financial and Other Applications
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作者 Prodromos Char. Papadopoulos 《Advances in Pure Mathematics》 2021年第5期524-572,共49页
In this research we are going to define two new concepts: a) “The Potential of Events” (EP) and b) “The Catholic Information” (CI). The term CI derives from the ancient Greek language and declares all the Catholic... In this research we are going to define two new concepts: a) “The Potential of Events” (EP) and b) “The Catholic Information” (CI). The term CI derives from the ancient Greek language and declares all the Catholic (general) Logical Propositions (<img src="Edit_5f13a4a5-abc6-4bc5-9e4c-4ff981627b2a.png" width="33" height="21" alt="" />) which will true for every element of a set A. We will study the Riemann Hypothesis in two stages: a) By using the EP we will prove that the distribution of events e (even) and o (odd) of Square Free Numbers (SFN) on the axis Ax(N) of naturals is Heads-Tails (H-T) type. b) By using the CI we will explain the way that the distribution of prime numbers can be correlated with the non-trivial zeros of the function ζ(s) of Riemann. The Introduction and the Chapter 2 are necessary for understanding the solution. In the Chapter 3 we will present a simple method of forecasting in many very useful applications (e.g. financial, technological, medical, social, etc) developing a generalization of this new, proven here, theory which we finally apply to the solution of RH. The following Introduction as well the Results with the Discussion at the end shed light about the possibility of the proof of all the above. The article consists of 9 chapters that are numbered by 1, 2, …, 9. 展开更多
关键词 Twin Problem Twins Problem Unsolved Mathematical Problems Prime Number Problems Millennium Problems Riemann Hypothesis Riemanns Hypothesis Number Theory Information Theory Probabilities Statistics Management Financial Applications Arithmetical Analysis Optimization Theory Stock Exchange Mathematics Approximation Methods Manifolds Economical Mathematics Random Variables Space of events Strategy Games Probability Density Stock Market Technical Analysis Forecasting
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Clinical decision support for drug related events: Moving towards better prevention 被引量:2
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作者 Sandra L Kane-Gill Archita Achanta +1 位作者 John A Kellum Steven M Handler 《World Journal of Critical Care Medicine》 2016年第4期204-211,共8页
Clinical decision support(CDS) systems with automated alerts integrated into electronic medical records demonstrate efficacy for detecting medication errors(ME) and adverse drug events(ADEs). Critically ill patients a... Clinical decision support(CDS) systems with automated alerts integrated into electronic medical records demonstrate efficacy for detecting medication errors(ME) and adverse drug events(ADEs). Critically ill patients are at increased risk for ME, ADEs and serious negative outcomes related to these events. Capitalizing on CDS to detect ME and prevent adverse drug related events has the potential to improve patient outcomes. The key to an effective medication safety surveillance system incorporating CDS is advancing the signals for alerts by using trajectory analyses to predict clinical events, instead of waiting for these events to occur. Additionally, incorporating cutting-edge biomarkers into alert knowledge in an effort to identify the need to adjust medication therapy portending harm will advance the current state of CDS. CDS can be taken a step further to identify drug related physiological events, which are less commonly included in surveillance systems. Predictive models for adverse events that combine patient factors with laboratory values and biomarkers are being established and these models can be the foundation for individualized CDS alerts to prevent impending ADEs. 展开更多
关键词 Drug-related side effects and ADVERSE reactions DECISION support SYSTEMS CLINICAL Medication errors Patient safety CLINICAL pharmacy information SYSTEMS Intensive CARE units Critical CARE ADVERSE DRUG event CLINICAL DECISION support SYSTEMS
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Evaluating the risk of adverse events with interventional endoscopic retrograde cholangiopancreatography and endoscopic ultrasound procedures in cirrhotic patients 被引量:1
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作者 Timothy Yoo Raisa Epistola +5 位作者 Jordan Epistola Lawrence Ku Michael W Fleischman Sofiya Reicher Viktor E Eysselein Linda A Hou 《World Journal of Gastrointestinal Endoscopy》 CAS 2019年第11期523-530,共8页
BACKGROUND Hepatic cirrhosis is associated with greater adverse event rates following surgical procedures and is thought to have a higher risk of complications with interventional procedures in general.However,these s... BACKGROUND Hepatic cirrhosis is associated with greater adverse event rates following surgical procedures and is thought to have a higher risk of complications with interventional procedures in general.However,these same patients often require interventional gastrointestinal procedures such as endoscopic retrograde cholangiopancreatography(ERCP)and endoscopic ultrasound(EUS).While studies examining this scenario exist,the overall body of evidence for adverse event rates associated with ERCP/EUS procedures is more limited.We sought add to the literature by examining the incidence of adverse events after ERCP/EUS procedures in our safety-net hospital population with the hypothesis that severity of cirrhosis correlates with higher adverse event rates.AIM To examine whether increasing severity of cirrhosis is associated with greater incidence of adverse events after interventional ERCP/EUS procedures.METHODS We performed a retrospective study of patients diagnosed with hepatic cirrhosis who underwent ERCP and/or EUS-guided fine needle aspirations/fine needle biopsies from January 1,2016 to March 14,2019 at our safety net hospital.We recorded Child-Pugh and Model for End-stage Liver Disease(MELD-Na)scores at time of procedure,interventions completed,and 30-day post-procedural adverse events.Statistical analyses were done to assess whether Child-Pugh class and MELD-Na score were associated with greater adverse event rates and whether advanced techniques(single-operator cholangioscopy,electrohydraulic lithotripsy/laser lithotripsy,or needle-knife techniques)were associated with higher complication rates.RESULTS 77 procedures performed on 36 patients were included.The study population consisted primarily of middle-aged Hispanic males.30-d procedure-related adverse events included gastrointestinal bleeding(7.8%),infection(6.5%),and bile leak(2%).The effect of Child-Pugh class C vs class A and B significantly predicted adverse events(β=0.55,P<0.01).MELD-Na scores also significantly predicted adverse events(β=0.037,P<0.01).Presence of advanced techniques was not associated with higher adverse events(P>0.05).When MELD-Na scores were added as predictors with the effect of Child-Pugh class C,logistic regression showed MELD-Na scores were a significant predictor of adverse events(P<0.01).The findings held after controlling for age,gender,ethnicity and repeat cases.CONCLUSION Increasing cirrhosis severity predicted adverse events while the presence of advanced techniques did not.MELD-Na score may be more useful in predicting adverse events than Child-Pugh class. 展开更多
关键词 ENDOSCOPIC retrograde CHOLANGIOPANCREATOGRAPHY ENDOSCOPIC ultrasound FINE-NEEDLE ASPIRATION FINE-NEEDLE biopsy Hepatic cirrhosis Model for END-STAGE Liver Disease CHILD-PUGH Class Adverse events
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Analysis of Nonlinear Stochastic Systems with Jumps Generated by Erlang Flow of Events
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作者 Alexander S. Kozhevnikov Konstantin A. Rybakov 《Open Journal of Applied Sciences》 2013年第1期1-7,共7页
In this paper we consider the stochastic systems with jumps (random impulses) generated by Erlang flow of events that lead to discontinuities in paths. These systems may be used in various applications such as a contr... In this paper we consider the stochastic systems with jumps (random impulses) generated by Erlang flow of events that lead to discontinuities in paths. These systems may be used in various applications such as a control of complex technical systems, financial mathematics, mathematical biology and medicine. We propose to use a spectral method formalism to the probabilistic analysis problem for the stochastic systems with jumps. This method allows to get a solution of the analysis problem in an explicit form. 展开更多
关键词 ANALYSIS ERLANG FLOW of events Generalized Fokker-Planck Equations Random Impulses JUMP-DIFFUSION Process SPECTRAL Characteristic SPECTRAL Method Formalism Stochastic System
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Childhood stressful events, HPA axis and anxiety disorders 被引量:6
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作者 Carlo Faravelli Carolina Lo Sauro +7 位作者 Lucia Godini Lorenzo Lelli Laura Benni Francesco Pietrini Lisa Lazzeretti Gabriela Alina Talamba Giulia Fioravanti Valdo Ricca 《World Journal of Psychiatry》 SCIE 2012年第1期13-25,共13页
Anxiety disorders are among the most common of all mental disorders and their pathogenesis is a major topic in psychiatry, both for prevention and treatment. Early stressful life events and alterations of hypothalamic... Anxiety disorders are among the most common of all mental disorders and their pathogenesis is a major topic in psychiatry, both for prevention and treatment. Early stressful life events and alterations of hypothalamic pituitary adrenal(HPA) axis function seem to have a significant role in the onset of anxiety. Existing data appear to support the mediating effect of the HPA axis between childhood traumata and posttraumatic stress disorder. Findings on the HPA axis activity at baseline and after stimuli in panic disordered patients are inconclusive, even if stressful life events may have a triggering function in the development of this disorder. Data on the relationship between stress, HPA axis functioning and obsessive-compulsive disorder(OCD) are scarce and discordant, but an increased activity of the HPA axis is reported in OCD patients. Moreover, normal basal cortisol levels and hyperresponsiveness of the adrenal cortex during a psychosocial stressor are observed in social phobics. Finally,abnormal HPA axis activity has also been observed in generalized anxiety disordered patients. While several hypothesis have attempted to explain these findings over time, currently the most widely accepted theory is that early stressful life events may provoke alterations of the stress response and thus of the HPA axis, that can endure during adulthood, predisposing individuals to develop psychopathology. All theories are reviewed and the authors conclude that childhood life events and HPA abnormalities may be specifically and transnosographically related to all anxiety disorders, as well as, more broadly, to all psychiatric disorders. 展开更多
关键词 Anxiety disorders Early stressful life events CHILDHOOD traumata CORTISOL HYPOTHALAMIC PITUITARY ADRENAL axis Vulnerability PSYCHOPATHOLOGY
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Heinrich events recorded in a loess-paleosol sequence from Hexigten,Inner Mongolia 被引量:2
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作者 Ji-Ling Song Hong-Yan Sun +3 位作者 Ming-Zhong Tian Xu-Jiao Zhang Xue-Feng Wen Miao Sun 《Geoscience Frontiers》 SCIE CAS CSCD 2018年第2期431-439,共9页
We describe the last glaciation climatic history Marine Isotope Stage(MIS, 2-4) from 66.7 ka to 14.5 ka in Hexigten, northeast Inner Mongolia, North China. The climate of the region experienced frequent and significan... We describe the last glaciation climatic history Marine Isotope Stage(MIS, 2-4) from 66.7 ka to 14.5 ka in Hexigten, northeast Inner Mongolia, North China. The climate of the region experienced frequent and significant fluctuations between dry-cold and less dry-cold during the late MIS4. The climate was generally warm and humid during early MIS3(MIS3 c) and late MIS3(MIS3 a), whereas it was cold and dry in middle MIS3(MIS3 b) and during MIS2. In this study, the cold and dry conditions were correlated with a stronger East Asian winter monsoon and strong dune activity; whereas, warm and humid conditions were related to a stronger East Asian summer monsoon(EASM) and weak dune activity. This study establishes six distinct dry and cold intervals during the last glacial period(66.7-14.5 ka) based on optically stimulated luminescence data, multi-proxies record(magnetic susceptibility, grain size analysis, Rb/Sr, SiO2/TiO2) and chemical index of alteration(CIA). The last glacial period may be correlated with Heinrich events 1 to 6 which were further confirmed by comparison with the Hulu cave stalagmites and Greenland ice core records. It is concluded that the study area was substantially affected by the EASM, as compared with the loess-desert transition zone of the Chinese Loess Plateau, especially in MIS3 c and suggested that the East Asian monsoon played a pivotal role in the last glacial period climate and dune activity. 展开更多
关键词 Climate record DUNE activity Inner Mongolia East ASIAN MONSOON Marine ISOTOPE stage 2-4 Heinrich events
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Commentary on“Accelerometer-measured physical activity,sedentary behavior,and incidence of macrovascular and microvascular events in individuals with type 2 diabetes mellitus and prediabetes” 被引量:1
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作者 Barbara E.Ainsworth Haili Tian 《Journal of Sport and Health Science》 2025年第1期3-5,共3页
Type 2 diabetes(T2D)is an insidious disease associated with neural and vascular complications,acceleration of cardiovascular disease,changes in heart function,and premature death.In the newly released article of the J... Type 2 diabetes(T2D)is an insidious disease associated with neural and vascular complications,acceleration of cardiovascular disease,changes in heart function,and premature death.In the newly released article of the Journal of Sport and Health Science,Liang et al.1 describe results from the UK Biobank data showing the benefits of moderate-to-vigorous intensity physical activity(MVPA)on reducing the risks for vascular events in 11,474 adults with T2D and prediabetes. 展开更多
关键词 PREDIABETES type diabetes t d sedentary behavior vascular events macrovascular events type diabetes mellitus microvascular events
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Myeloperoxidase and High-Sensitivity C-Reactive Protein for Predicting Major Adverse Cardiovascular Events in Patients with Coronary Heart Disease 被引量:6
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作者 Chenggui Liu Linong Chen +3 位作者 Yinzhong Yang Cheng Huang Jun Luo Duanliang Peng 《International Journal of Clinical Medicine》 2015年第4期262-270,共9页
Background: Research has shown that high-sensitivity C-reactive protein (hs-CRP) is a major inflammatory marker for prediction of acute coronary syndrome (ACS). Myeloperoxidase (MPO) also plays an important role in at... Background: Research has shown that high-sensitivity C-reactive protein (hs-CRP) is a major inflammatory marker for prediction of acute coronary syndrome (ACS). Myeloperoxidase (MPO) also plays an important role in atherosclerosis initiation and development. In present study, the major adverse cardiovascular events (MACEs) of patients with coronary heart disease (CHD) were investigated. Methods: MPO, hs-CRP and ACS-related risk factors from 201 ACS (78 AMI and 123 UAP) and 210 non-ACS (84 SAP and 126 non-CHD) patients confirmed by coronary angiography were detected, and the data were analyzed with receiver operating characteristic (ROC) curve and Spearman’s correlation coefficients. MACEs of 285 CHD patients were investigated during the 4-year period follow-up from March 2010 to May 2014. Results: The areas under ROC curve for diagnosing ACS were 0.888 (95% CI 0.843 - 0.933) for MPO, and 0.862 (95% CI 0.815-0.910) for hs-CRP, respectively. There were significantly correlations between MPO and hs-CRP in both ACS and non-ACS groups. Regarding to ACS patients, both MPO and hs-CRP were positively correlated with BMI, TC, TG, LDL-C and Hcy. Prospective study demonstrated that the incidences of MACEs associated significantly with elevated MPO baseline level (yes vs no, OR 7.383, 95% CI 4.095 - 13.309) and high hs-CRP baseline level (yes vs no, OR 4.186, 95% CI 2.469 - 7.097) in CHD patients. Conclusions: The present study provides the epidemiological evidence that elevated baseline MPO and hs-CRP levels are both valuable predictors of MACEs in CHD patients. MPO and hs-CRP would prompt the progression of atherosclerosis and development from SAP to ACS. 展开更多
关键词 MYELOPEROXIDASE High Sensitivity C-Reactive Protein Acute CORONARY SYNDROME CORONARY HEART Disease Major ADVERSE CARDIOVASCULAR events
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Spatiotemporal Evolution of Waterlogging Events in Eastern China from 1961 to 2016
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作者 KONG Feng 《Journal of Landscape Research》 2019年第4期64-72,77,共10页
In this study, based on the data on the frequency of waterlogging events and the number of waterlogging days of 1,638 stations from 1961 to 2016, a variety of mathematical statistics methods were used to analyze the s... In this study, based on the data on the frequency of waterlogging events and the number of waterlogging days of 1,638 stations from 1961 to 2016, a variety of mathematical statistics methods were used to analyze the spatiotemporal evolution of waterlogging events in eastern China. The results showed that:① In terms of time, the annual frequency of waterlogging events and the number of waterlogging days in eastern China in 1961–2016 showed an increasing trend despite of fluctuations. In the interdecadal changes, the highest frequency of waterlogging events and the greatest number of waterlogging days occurred in the 1990s, and from the 1960s to the 1980s, the frequency of waterlogging events and the number of waterlogging days in eastern China showed a decreasing trend. There were 6-year and 30-year periodic variations in the frequency of waterlogging events and the number of waterlogging days in eastern China, and mutations occurred in 1991.② In terms of space, from 1961 to 2016, the areas with high frequency of waterlogging events in various years in eastern China were mainly South China, western and southern Yunnan, northern Jiangsu, southern Zhejiang, northern Fujian, junction areas between Hunan and Chongqing, northern Sichuan, and eastern Liaoning.③ In the spatial distribution of change trends and fluctuation characteristics, the frequency of waterlogging events and the number of waterlogging days in eastern China increased significantly in the southeastern coastal areas from 1961 to 2016, and the fluctuations of the frequency of waterlogging events and the number of waterlogging days in eastern China from 1961 to 2016 presented a spatial variation pattern of low in the southwest and high in the northwest. 展开更多
关键词 WATERLOGGING event SPATIOTEMPORAL pattern MANN-KENDALL (MK) test ENSEMBLE empirical mode decomposition (EEMD) WAVELET analysis Climate change
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Impact of extreme weather and climate events on crop yields in the Tarim River Basin,China
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作者 WANG Xiaochen LI Zhi +6 位作者 CHEN Yaning ZHU Jianyu WANG Chuan WANG Jiayou ZHANG Xueqi FENG Meiqing LIANG Qixiang 《Journal of Arid Land》 2025年第2期200-223,共24页
The Tarim River Basin(TRB)is a vast area with plenty of light and heat and is an important base for grain and cotton production in Northwest China.In the context of climate change,however,the increased frequency of ex... The Tarim River Basin(TRB)is a vast area with plenty of light and heat and is an important base for grain and cotton production in Northwest China.In the context of climate change,however,the increased frequency of extreme weather and climate events is having numerous negative impacts on the region's agricultural production.To better understand how unfavorable climatic conditions affect crop production,we explored the relationship of extreme weather and climate events with crop yields and phenology.In this research,ten indicators of extreme weather and climate events(consecutive dry days(CDD),min Tmax(TXn),max Tmin(TNx),tropical nights(TR),warm days(Tx90p),warm nights(Tn90p),summer days(SU),frost days(FD),very wet days(R95p),and windy days(WD))were selected to analyze the impact of spatial and temporal variations on the yields of major crops(wheat,maize,and cotton)in the TRB from 1990 to 2020.The three key findings of this research were as follows:extreme temperatures in southwestern TRB showed an increasing trend,with higher extreme temperatures at night,while the occurrence of extreme weather and climate events in northeastern TRB was relatively low.The number of FD was on the rise,while WD also increased in recent years.Crop yields were higher in the northeast compared with the southwest,and wheat,maize,and cotton yields generally showed an increasing trend despite an earlier decline.The correlation of extreme weather and climate events on crop yields can be categorized as extreme nighttime temperature indices(TNx,Tn90p,TR,and FD),extreme daytime temperature indices(TXn,Tx90p,and SU),extreme precipitation indices(CDD and R95p),and extreme wind(WD).By using Random Forest(RF)approach to determine the effects of different extreme weather and climate events on the yields of different crops,we found that the importance of extreme precipitation indices(CDD and R95p)to crop yield decreased significantly over time.As well,we found that the importance of the extreme nighttime temperature(TR and TNx)for the yields of the three crops increased during 2005-2020 compared with 1990-2005.The impact of extreme temperature events on wheat,maize,and cotton yields in the TRB is becoming increasingly significant,and this finding can inform policy decisions and agronomic innovations to better cope with current and future climate warming. 展开更多
关键词 extreme events extreme nighttime heat Tarim River Basin crop yield random forest model WHEAT MAIZE cotton PHENOLOGY
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Towards personalized care in minimally invasive esophageal surgery:An adverse events prediction model
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作者 Ioannis Karniadakis Alexandra Argyrou +1 位作者 Stamatina Vogli Stavros P Papadakos 《World Journal of Gastroenterology》 2025年第13期155-157,共3页
This letter addressed the impactful study by Zhong et al,which introduced a risk prediction and stratification model for surgical adverse events following minimally invasive esophagectomy.By identifying key risk facto... This letter addressed the impactful study by Zhong et al,which introduced a risk prediction and stratification model for surgical adverse events following minimally invasive esophagectomy.By identifying key risk factors such as chronic obstructive pulmonary disease and hypoalbuminemia,the model demonstrated strong predictive accuracy and offered a pathway to personalized perioperative care.This correspondence highlighted the clinical significance,emphasizing its potential to optimize patient outcomes through tailored inter-ventions.Further prospective validation and application across diverse settings are essential to realize its full potential in advancing esophageal surgery practices. 展开更多
关键词 Minimally invasive esophagectomy Surgical adverse events Risk prediction model Risk stratification HYPOALBUMINEMIA Predictive accuracy Personalized perioperative care Tailored interventions Esophageal surgery
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Spatial pattern of hourly precipitation events in China revealed by precipitation event detection indices
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作者 ZHANG Yihui LIANG Kang LIU Changming 《Journal of Geographical Sciences》 2026年第1期129-148,共20页
Precipitation events,which follow a life cycle of initiation,development,and decay,represent the fundamental form of precipitation.Comprehensive and accurate detection of these events is crucial for effective water re... Precipitation events,which follow a life cycle of initiation,development,and decay,represent the fundamental form of precipitation.Comprehensive and accurate detection of these events is crucial for effective water resource management and flood control.However,current investigations on their spatio-temporal patterns remain limited,largely because of the lack of systematic detection indices that are specifically designed for precipitation events,which constrains event-scale research.In this study,we defined a set of precipitation event detection indices(PEDI)that consists of five conventional and fourteen extreme indices to characterize precipitation events from the perspectives of intensity,duration,and frequency.Applications of the PEDI revealed the spatial patterns of hourly precipitation events in China and its first-and second-order river basins from 2008 to 2017.Both conventional and extreme precipitation events displayed spatial distribution patterns that gradually decreased in intensity,duration,and frequency from southeast to northwest China.Compared with those in northwest China,the average values of most PEDIs in southeast China were usually 2-10 times greater for first-order river basins and 3-15 times greater for second-order basins.The PEDI could serve as a reference method for investigating precipitation events at global,regional,and basin scales. 展开更多
关键词 precipitation events precipitation event detection indices(PEDI) spatial heterogeneity IETD(inter-event time definition)method
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Moisture sources of extreme summer precipitation events in North Xinjiang and their relationship with atmospheric circul 被引量:17
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作者 HUANG Wei CHANG Shi-Qiao +1 位作者 XIE Cheng-Ling ZHANG Zhi-Ping 《Advances in Climate Change Research》 SCIE CSCD 2017年第1期12-17,共6页
In this study, the daily observational precipitation data and NCEP reanalysis data during 1951e2014, Euler and Lagrangian method were used to investigate the moisture sources of summer extreme precipitation events in ... In this study, the daily observational precipitation data and NCEP reanalysis data during 1951e2014, Euler and Lagrangian method were used to investigate the moisture sources of summer extreme precipitation events in North Xinjiang. The results show that water vapor at low and upper levels of most summer heavy rain (more than 50 mm d1 and less than 100 mm d1) in North Xinjiang are mainly transported by westerly circulation from the North Atlantic Ocean and the Eurasian continent. However, rainstorms of more than 100 mm d1, which are rarely observed, are dominated by vertically integrated moisture from the North Atlantic, Arctic Oceans, and the Eurasian continent, in addition to lowlevel moisture from the Indian Ocean. Among these sources, the anomalous low-level moisture from the Indian Ocean, which is closely associated with stronger meridional circulation, is considered to be more important with respect to rainstorms. On the days prior to rainstorm days, stronger meridional circulation leads to an anomalous pressure gradient force, which can transport low-level moisture from the Indian Ocean along the eastern periphery of the Tibetan Plateau to North Xinjiang. Furthermore, moisture from the North Atlantic, Arctic Oceans, the Eurasian continent, and the Indian Ocean converge together to influence rainstorm development in this region. 展开更多
关键词 NORTH XINJIANG Moisture sources EXTREME precipitation events LAGRANGIAN trajectory model INDIAN Ocean
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Predictors of life-threatening events in adult patients with left ventricular noncompaction
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作者 Olga V Blagova Nadezhda V Varionchik +2 位作者 Ekaterina V Pavlenko Vsevolod P Sedov Yulia A Lutokhina 《World Journal of Cardiology》 2025年第12期117-129,共13页
BACKGROUND Left ventricular noncompaction(LVNC)is a genetic cardiomyopathy.It is characterized by intensely developed trabeculae in the ventricles with deep intertrabecular lacunae.LVNC manifests as arrhythmias and he... BACKGROUND Left ventricular noncompaction(LVNC)is a genetic cardiomyopathy.It is characterized by intensely developed trabeculae in the ventricles with deep intertrabecular lacunae.LVNC manifests as arrhythmias and heart failure with a predisposition for thrombus formation.AIM To study predictors of arrhythmic,thromboembolic events and adverse outcomes(death/transplantation)in adult patients with LVNC.METHODS Adult patients with LVNC were included(n=125;mean follow-up:14 months).Electrocardiography,echocardiography,and 24-hour electrocardiography monitoring were performed.Other procedures were conducted for some patients including:Coronary angiography;cardiac magnetic resonance imaging;cardiac computed tomography;genetic testing;myocardial pathological examination;and anti-cardiac antibody level estimation.Primary endpoints were death,heart transplantation,combined endpoint(death+transplantation),and sudden cardiac death.Secondary endpoints were intracardiac thrombosis,embolic events,myocardial infarction,sustained ventricular tachycardia(VT),and implantable cardioverter-defibrillator intervention.RESULTS LVNC manifestations included non-sustained VT,thrombosis/embolism,sustained VT, and sudden cardiac death. Non-sustained VT was associated with the New York Heart Association(NYHA) chronic heart failure (CHF) class, poor R-wave progression, superimposed myocarditis, and highermortality. Thrombosis/embolism was associated with NYHA CHF class ≥ 3, right ventricular end-diastolicdiameter ≥ 3 cm, right atrium volume ≥ 67 mL, left ventricle end-diastolic diameter ≥ 6.3 cm, and velocity timeintegral ≤ 11.2 cm. Sustained VT was associated with premature ventricular contractions (PVCs), low QRS voltage,and atrioventricular block. PVCs > 500/day were predictive of defibrillator intervention. Fatal outcomes wereassociated with E wave/A wave ratio > 1.9, left ventricle ejection fraction < 35%, NYHA CHF class ≥ 3, VT, andmyocarditis.CONCLUSIONFrequent PVCs, non-sustained VT, low QRS voltage, and signs of systolic dysfunction on echocardiogram arepredictors of life-threatening events in patients with LVNC. 展开更多
关键词 Left ventricular noncompaction PREDICTORS Arrhythmic events Thromboembolic events Adverse outcomes MYOCARDITIS Heart failure
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Zircon U-Pb dating of metagabbro masses from the Liwu Group Complex within the Taka dome:Geochronological constraints on the Indosinian-Yanshanian tectonic events in western Sichuan,China
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作者 Hong-chao Zhang Hong-bing Zhou +7 位作者 Bo Yan Chong-bo Sun Yue-zhong Wang Yun-chuan Zhao Yao Wen Ren-liang Cao Yang Qin Hong-qi Tan 《China Geology》 2025年第4期865-868,I0004-I0006,共7页
1.Objective The Songpan-Ganze terrane is a key region for understanding the tectonic evolution of the Tibetan Plateau and the Yangtze Craton.The Songpan-Ganzi complex comprises a thick succession of deformed Ladinian-... 1.Objective The Songpan-Ganze terrane is a key region for understanding the tectonic evolution of the Tibetan Plateau and the Yangtze Craton.The Songpan-Ganzi complex comprises a thick succession of deformed Ladinian-Norian turbidites(ca.230-203 Ma),covering about 200000 km^(2)of the eastern Tibet Plateau with a volume of approximately 2.0×10^(6)km^(3)(Fig.1a).Furthermore,this complex has over 100 Permian-Cenozoic felsic plutons. 展开更多
关键词 u pb dating INDOSINIAN zircon METAGABBRO taka dome YANSHANIAN liwu group complex tectonic events
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Revisiting the trading activity of high‑frequency trading firms around ultra‑fast flash events
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作者 Christophe Desagre Floris Laly Mikael Petitjean 《Financial Innovation》 2025年第1期1897-1933,共37页
We investigate high-frequency traders’behavior in the context of the fastest and most extreme price movements(EPMs)that can be observed in the market,specifically ultrafast flash events,challenging the methodologies ... We investigate high-frequency traders’behavior in the context of the fastest and most extreme price movements(EPMs)that can be observed in the market,specifically ultrafast flash events,challenging the methodologies employed in the academic and practitioner literature for identifying sudden liquidity black holes.To refine the price-shock identification methodology,we introduce a new approach called sequence-based flash events(SFEs),which relies on tick sequences instead of predetermined fixed-time intervals within which all flash events in the sample are assumed to occur.This alternative methodology offers the advantage of pinpointing the exact time and duration of a crash,which,in turn,provides a way to more accurately define the observation windows around it.We compare our sample of SFEs with both the so-called“mini flash crashes”,as identified by the Nanex detection algorithm,and the so-called EPMs,as identified by Brogaard et al.(2018).We use close and open prices,as well as high and low prices.Based on our sample of SFEs,we find no evidence that HFTs trigger extreme price shocks.However,we find that HFTs exacerbate SFEs by increasing the net imbalance in the direction of these shocks as they occur.Finally,we show that the choice of the price-shock identification methodology is critical.Thus,we urge regulators to exercise caution and avoid hasty conclusions regarding HFTs’contribution to price stability in stressful market conditions. 展开更多
关键词 Flash events Mini flash crashes Extreme price movements Highfrequency trading Trading activity LIQUIDITY Market stability Market microstructure
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Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis
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作者 Charmaine E Lok 《四川生理科学杂志》 2025年第11期2369-2369,共1页
Background:Cardiovascular disease is the leading cause of death in patients receiving hemodialysis,yet effective preventive therapies remain limited.Supplementation with n-3 polyunsaturated fatty acids,especially eico... Background:Cardiovascular disease is the leading cause of death in patients receiving hemodialysis,yet effective preventive therapies remain limited.Supplementation with n-3 polyunsaturated fatty acids,especially eicosapentaenoic acid(EPA)and docosahexaenoic acid(DHA),may have cardiovascular benefits in the general population,but efficacy among patients receiving hemodialysis is uncertain.Methods:In a double-blind,randomized,placebo-controlled trial conducted at 26 sites in Canada and Australia,we assigned adult patients receiving maintenance hemodialysis to daily supplementation with fish oil(4 g of n-3 polyunsaturated fatty acids[1.6 g of EPA and 0.8 g of DHA])or corn-oil placebo.The primary end point was a composite of all serious cardiovascular events including sudden and nonsudden cardiac death,fatal and nonfatal myocardial infarction,peripheral vascular disease leading to amputation,and fatal and nonfatal stroke. 展开更多
关键词 docosahexaenoic acid dha may docosahexaenoic acid fish oil cardiovascular events eicosapentaenoic acid epa eicosapentaenoic acid preventive therapies n polyunsaturated fatty acids
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Changes in soil microbial community response to precipitation events in a semi-arid steppe of the Xilin River Basin, China 被引量:6
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作者 ZHANG Hui LIU Wenjun +5 位作者 KANG Xiaoming CUI Xiaoyong WANG Yanfen ZHAO Haitao QIAN Xiaoqing HAO Yanbin 《Journal of Arid Land》 SCIE CSCD 2019年第1期97-110,共14页
In the context of climate change, precipitation is predicted to become more intense at the global scale. Such change may alter soil microbial communities and the microbially mediated carbon and nitrogen dynamics. In t... In the context of climate change, precipitation is predicted to become more intense at the global scale. Such change may alter soil microbial communities and the microbially mediated carbon and nitrogen dynamics. In this study, we experimentally repackaged precipitation patterns during the growing season(from June to September) of 2012 in a semi-arid temperate steppe of the Xilin River Basin in Inner Mongolia of China, based on the 60-year growing season precipitation data. Specifically, a total amount of 240 mm simulated precipitation was assigned to experimental plots by taking the following treatments:(1) P6(6 extreme precipitation events, near the 1^(st) percentile);(2) P10(10 extreme precipitation events, near the 5^(th) percentile);(3) P16(16 moderate precipitation events, near the 50^(th) percentile); and(4) P24(24 events, 60-year average precipitation, near the 50^(th) percentile). At the end of the growing season, we analyzed soil microbial community structure and biomass, bacterial abundance, fungal abundance and bacterial composition, by using phospholipid fatty acid(PLFA), real-time quantitative polymerase chain reaction(RT-qPCR) and 16S rRNA gene clone library methods. The extreme precipitation events did not change soil microbial community structure(represented by the ratio of PLFA concentration in fungi to PLFA concentration in bacteria, and the ratio of PLFA concentration in gram-positive bacterial biomass to PLFA concentration in gram-negative bacterial biomass). However, the extreme precipitation events significantly increased soil microbial activity(represented by soil microbial biomass nitrogen and soil bacterial 16S rRNA gene copy numbers). Soil fungal community showed no significant response to precipitation events. According to the redundancy analysis, both soil microbial biomass nitrogen and soil ammonium nitrogen(NH_4-N) were found to be significant in shaping soil microbial community. Acidobacteria, Actinobacteria and Proteobacteria were the dominant phyla in soil bacterial composition, and responded differently to the extreme precipitation events. Based on the results, we concluded that the extreme precipitation events altered the overall soil microbial activity, but did not impact how the processes would occur, since soil microbial community structure remained unchanged. 展开更多
关键词 extreme precipitation event PHOSPHOLIPID fatty acid (PLFA) SOIL microbial community RT-qPCR SOIL bacteria SOIL fungi
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Quantum Measurements Generating Structures of Numerical Events
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作者 Dietmar Dorninger Helmut Lä nger 《Journal of Applied Mathematics and Physics》 2018年第5期982-996,共15页
Let S be a set of states of a physical system and p(s) the probability of an occurrence of an event when the system is in state s∈S. The function p from S to [0,1] is called a numerical event, multidimensional probab... Let S be a set of states of a physical system and p(s) the probability of an occurrence of an event when the system is in state s∈S. The function p from S to [0,1] is called a numerical event, multidimensional probability or, more precisely, S-probability. If a set of numerical events is ordered by the order of real functions one obtains a partial ordered set P in which the sum and difference of S-probabilities are related to their order within P. According to the structure that arises, this further opens up the opportunity to decide whether one deals with a quantum mechanical situation or a classical one. In this paper we focus on the situation that P is generated by a given set of measurements, i.e. S-probabilities, without assuming that these S-probabilities can be complemented by further measurements or are embeddable into Boolean algebras, assumptions that were made in most of the preceding papers. In particular, we study the generation by S-probabilities that can only assume the values 0 and 1, thus dealing with so called concrete logics. We characterize these logics under several suppositions that might occur with measurements and generalize our findings to arbitrary S-probabilities, this way providing a possibility to distinguish between potential classical and quantum situations and the fact that an obtained structure might not be sufficient for an appropriate decision. Moreover, we provide some explanatory examples from physics. 展开更多
关键词 ORDERED STRUCTURES of NUMERICAL events Generating Processes Quantum LOGICS Concrete LOGICS EXAMPLES from Physics
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Conditional Events and Quantum Logic
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作者 Philip G. Calabrese 《Journal of Applied Mathematics and Physics》 2018年第6期1278-1289,共12页
This paper begins with an overview of quantum mechanics, and then recounts a relatively recent algebraic extension of the Boolean algebra of probabilistic events to “conditional events” (order pairs of events). The ... This paper begins with an overview of quantum mechanics, and then recounts a relatively recent algebraic extension of the Boolean algebra of probabilistic events to “conditional events” (order pairs of events). The main point is to show that a so-called “superposition” of two (or more) quantum events (usually with mutually inconsistent initial conditions) can be represented in this algebra of conditional events and assigned a consistent conditional probability. There is no need to imagine that a quantum particle can simultaneously straddle two inconsistent possibilities. 展开更多
关键词 HEISENBERG INDETERMINACY SUPERPOSITION of events Quantum Entanglement Hidden Variables BOOLEAN Algebra CONDITIONAL Logic
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