Hydrogels emerge as a promising electrode material for scalp electroencephalogram monitoring,which stands as a pivotal technique in neuroscience,enabling real-time monitoring of brain activity.However,conventional hyd...Hydrogels emerge as a promising electrode material for scalp electroencephalogram monitoring,which stands as a pivotal technique in neuroscience,enabling real-time monitoring of brain activity.However,conventional hydrogel-enabled electrodes suffer from low scalp compliance,high scalpelectrode impedance,and inferior interfacial stability.Here,we propose an injectable eutectogelenabled electrode for high-quality,long-term scalp electroencephalogram monitoring.This gelatinbased eutectogel exhibits temperature-controlled reversible phase transitions,enabling rapid in-situ gelation on the scalp and forming a robust self-adhesive interface.It demonstrates exceptional mechanical durability(1000 cycles at 100%strain),robust adhesion(0.7 N cm^(-1)on human epidermis and 1.7 N cm^(-1)on Ag/AgCl electrode),and outstanding anti-drying properties(negligible water loss after 7 days).Additionally,the eutectogel shows superior healing properties,antibacterial properties,and recyclability.Furthermore,it exhibits remarkably low scalp-electrode contact impedance(<20 kΩat 16 Hz).The eutectogel is injected on the human scalp with dense hair for high-fidelity electroencephalogram recording,enabling long-term monitoring.Its practical applications include monitoring visual evoked potentials,steady-state visual evoked potentials,somatosensory evoked potentials,slow vertex response,auditory brainstem response,multi-channel cognitive electroencephalogram during various daily activities,and event-related potentials P300 signals.The eutectogel-enabled electrode provides a versatile and reliable solution for long-term electroencephalogram monitoring in diverse clinical and research settings.展开更多
基金support from the National Natural Science Foundation of China(grant Nos.:52303371,W2521021)Guangdong Science and Technology Department(grant Nos.:STKJ2023075,2022A1515110209,2021B0301030005)Education foundation of Guangdong Technion-Israel institute of Technology,and the Key Discipline(KD)Fund,the Technion,and the Start-Up Fund from Guangdong Technion.
文摘Hydrogels emerge as a promising electrode material for scalp electroencephalogram monitoring,which stands as a pivotal technique in neuroscience,enabling real-time monitoring of brain activity.However,conventional hydrogel-enabled electrodes suffer from low scalp compliance,high scalpelectrode impedance,and inferior interfacial stability.Here,we propose an injectable eutectogelenabled electrode for high-quality,long-term scalp electroencephalogram monitoring.This gelatinbased eutectogel exhibits temperature-controlled reversible phase transitions,enabling rapid in-situ gelation on the scalp and forming a robust self-adhesive interface.It demonstrates exceptional mechanical durability(1000 cycles at 100%strain),robust adhesion(0.7 N cm^(-1)on human epidermis and 1.7 N cm^(-1)on Ag/AgCl electrode),and outstanding anti-drying properties(negligible water loss after 7 days).Additionally,the eutectogel shows superior healing properties,antibacterial properties,and recyclability.Furthermore,it exhibits remarkably low scalp-electrode contact impedance(<20 kΩat 16 Hz).The eutectogel is injected on the human scalp with dense hair for high-fidelity electroencephalogram recording,enabling long-term monitoring.Its practical applications include monitoring visual evoked potentials,steady-state visual evoked potentials,somatosensory evoked potentials,slow vertex response,auditory brainstem response,multi-channel cognitive electroencephalogram during various daily activities,and event-related potentials P300 signals.The eutectogel-enabled electrode provides a versatile and reliable solution for long-term electroencephalogram monitoring in diverse clinical and research settings.
