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RESEARCH ON PREVIEW CONTROL TECHNIQUE BASED ON EXTENDED ERROR SYSTEM WITH DELAY
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作者 Zhang Xiaomei Wang Zhanlin(Faculty 303, Beijing University of Aeronautics andAstronautics, Beijing, 100083, China) 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 1997年第1期58-61,共4页
A valid preview control technique is presented for processing servo systemswith input delay based on extended error systems with input delay. The technique usesthe concept of error systems, establishes extended error ... A valid preview control technique is presented for processing servo systemswith input delay based on extended error systems with input delay. The technique usesthe concept of error systems, establishes extended error systems with input delay and de-rives preview control laws based on minimization of evaluation function. Finally, simula-tion is done on linear direct current motor without brush. The results reveal that the tech-nique proposed herein is valid for improving performance of servo systems. 展开更多
关键词 error system preview control servo system
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Auxiliary Model Based Multi-innovation Stochastic Gradient Identification Methods for Hammerstein Output-Error System
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作者 冯启亮 贾立 李峰 《Journal of Donghua University(English Edition)》 EI CAS 2017年第1期53-59,共7页
Special input signals identification method based on the auxiliary model based multi-innovation stochastic gradient algorithm for Hammerstein output-error system was proposed.The special input signals were used to rea... Special input signals identification method based on the auxiliary model based multi-innovation stochastic gradient algorithm for Hammerstein output-error system was proposed.The special input signals were used to realize the identification and separation of the Hammerstein model.As a result,the identification of the dynamic linear part can be separated from the static nonlinear elements without any redundant adjustable parameters.The auxiliary model based multi-innovation stochastic gradient algorithm was applied to identifying the serial link parameters of the Hammerstein model.The auxiliary model based multi-innovation stochastic gradient algorithm can avoid the influence of noise and improve the identification accuracy by changing the innovation length.The simulation results show the efficiency of the proposed method. 展开更多
关键词 Hammerstein output-error system special input signals auxiliary model based multi-innovation stochastic gradient algorithm innovation length
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M-Estimation-Based Minimum Error Entropy with Affine Projection Algorithm for Outlier Suppression in Spaceborne SAR System
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作者 WANG Weixin CHANG Xuelian OU Shifeng 《Transactions of Nanjing University of Aeronautics and Astronautics》 2025年第5期615-628,共14页
Conventional adaptive filtering algorithms often exhibit performance degradation when processing multipath interference in raw echoes of spaceborne synthetic aperture radar(SAR)systems due to anomalous outliers,manife... Conventional adaptive filtering algorithms often exhibit performance degradation when processing multipath interference in raw echoes of spaceborne synthetic aperture radar(SAR)systems due to anomalous outliers,manifesting as insufficient convergence and low estimation accuracy.To address this issue,this study proposes a novel robust adaptive filtering algorithm,namely the M-estimation-based minimum error entropy with affine projection(APMMEE)algorithm.This algorithm inherits the joint multi-data-block update mechanism of the affine projection algorithm,enabling rapid adaptation to the dynamic characteristics of raw echoes and achieving fast convergence.Meanwhile,it incorporates the M-estimation-based minimum error entropy(MMEE)criterion,which weights error samples in raw echoes through M-estimation functions,effectively suppressing outlier interference during the algorithm update.Both the system identification simulations and practical multipath interference suppression experiments using raw echoes demonstrate that the proposed APMMEE algorithm exhibits superior filtering performance. 展开更多
关键词 radar signal adaptive filtering minimum error entropy M-ESTIMATION affine projection
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Optimal Scheduling and On-the-Fly Flexible Control of Integrated Energy Systems for Residential Buildings Considering Photovoltaic Prediction Errors
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作者 Ziqing Wei Xiaoqiang Zhai Ruzhu Wang 《Engineering》 2025年第10期104-115,共12页
The integrated energy systems(IESs)offer a practical solution for achieving low-carbon targets in residential buildings.However,IES encounters several challenges related to increased energy consumption and costs due t... The integrated energy systems(IESs)offer a practical solution for achieving low-carbon targets in residential buildings.However,IES encounters several challenges related to increased energy consumption and costs due to fluctuations in renewable energy generation.Leveraging building flexibility to address these power fluctuations within IES is a promising strategy,which requires coordinated control between air-conditioning systems and other IES components.This study proposes a cross-time-scale control framework that contains optimal scheduling and on-the-fly flexible control to reduce the cost impacts of a residential IES system equipped with photovoltaic(PV)panels,batteries,a heat pump,and a domestic hot water tank.The method involves three key steps:solar irradiance prediction,day-ahead optimal scheduling of energy storage,and intra-day flexible control of the heat pump.The method is validated through a high-fidelity residential building model with actual weather and energy usage data in Frankfurt,Germany.Results reveal that the proposed method limits the cost increase to just 2.67% compared to the day-ahead schedule,whereas the cost could increase by 7.39% without the flexible control.Additionally,computational efficiency is enhanced by transforming the mixed-integer programming(MIP)into nonlinear programming(NLP)problem via introducing action-exclusive constraints.This approach offers valuable support for residential IES operations. 展开更多
关键词 Integrated energy system Residential building flexibility Photovoltaic prediction errors Heat pump Model predictive control
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Channel-Adaptive Interleaving Pattern Design for LDPC Considering Burst-Errors in PON Systems
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作者 Zhang Lei Yang Chuanchuan Zhang Fan 《China Communications》 2025年第10期161-169,共9页
Recently,the NGPON2 standards organization has decided to deploy LDPC code in upstream and downstream channels in next-generation Ethernet passive optical network(NG-EPON)systems.However,PON upstream channels operate ... Recently,the NGPON2 standards organization has decided to deploy LDPC code in upstream and downstream channels in next-generation Ethernet passive optical network(NG-EPON)systems.However,PON upstream channels operate in burst-mode,hence the turn-on effects in optical network units(ONUs)may introduce burst errors,which are difficult for LDPC to deal with.One of the solutions is introducing an interleaver to convert consecutive burst errors into separate random errors.The traditional interleavers such as the block interleaver and the random interleaver,only consider dispersing the consecutive errors.In this paper,we present a design methodology for channel-adaptive interleaving pattern by joint optimizing of interleaving and LDPC decoding in PON systems deploying LDPC codes.After determining the interleaving pattern where the bits can be recovered with more reliable messages during LDPC iterative decoding,we map the bits from the potential locations of burst errors to the interleaving positions.By doing so,we can not only disperse the burst errors but also make full use of the LDPC code to improve its decoding performance.The numerical results show that the proposed interleaving scheme has a better performance under any burst-error length. 展开更多
关键词 burst error channel-adaptive low-density parity-check(LDPC) passive optical network(PON)
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Identifying Data-Flow Errors in Cyber-Physical Systems Based on the Simplified Merged Process of Petri Nets
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作者 Min Wang Yike Wang +4 位作者 Xiao Chen Lu Liu MengChu Zhou Xiaobing Sun Shanchen Pang 《IEEE/CAA Journal of Automatica Sinica》 2025年第10期2002-2014,共13页
Data-flow errors are prevalent in cyber-physical systems(CPS).Although various approaches based on business process modeling notation(BPMN)have been devised for CPS modeling,the absence of formal specifications compli... Data-flow errors are prevalent in cyber-physical systems(CPS).Although various approaches based on business process modeling notation(BPMN)have been devised for CPS modeling,the absence of formal specifications complicates the verification of data-flow.Formal techniques such as Petri nets are popularly used for identifying data-flow errors.However,due to their interleaving semantics,they suffer from the state-space explosion problem.As an unfolding method for Petri nets,the merged process(MP)technique can well represent concurrency relationships and thus be used to address this issue.Yet generating MP is complex and incurs substantial overhead.By designing and applyingα-deletion rules for Petri nets with data(PNDs),this work simplifies MP,thus resulting in simplified MP(SMP)that is then used to identify data-flow errors.Our approach involves converting a BPMN into a PND and then constructing its SMP.The algorithms are developed to identify data-flow errors,e.g.,redundantdata and lost-data ones.The proposed method enhances the efficiency and effectiveness of identifying data-flow errors in CPS.It is expected to prevent the problems caused by data-flow errors,e.g.,medical malpractice and economic loss in some practical CPS.Its practicality and efficiency of the proposed method through several CPS.Its significant advantages over the state of the art are demonstrated. 展开更多
关键词 Business process modelling notation(BPMN) cyberphysical system(CPS) data-flow errors discrete event system fault detection model simplification Petri net
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Detection of co-phasing error in segmented mirror based on extended Young’s interferometry combined with Vision Transformer
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作者 LIU Yin-ling YAO Chi +3 位作者 OUYANG Shang-tao WAN Yi-rong CHEN Mo LI Bin 《中国光学(中英文)》 北大核心 2026年第1期205-218,共14页
Due to the inability of manufacturing a single monolithic mirror at the 10-meter scales,segmented mirrors have become indispensable tools in modern astronomical research.However,to match the imaging performance of the... Due to the inability of manufacturing a single monolithic mirror at the 10-meter scales,segmented mirrors have become indispensable tools in modern astronomical research.However,to match the imaging performance of the monolithic counterpart,the sub-mirrors must maintain precise co-phasing.Piston error critically degrades segmented mirror imaging quality,necessitating efficient and precise detection.To ad-dress the limitations that the conventional circular-aperture diffraction with two-wavelength algorithm is sus-ceptible to decentration errors,and the traditional convolutional neural networks(CNNs)struggle to capture global features under large-range piston errors due to their restricted local receptive fields,this paper pro-poses a method that integrates extended Young’s interference principles with a Vision Transformer(ViT)to detect piston error.By suppressing decentration error interference through two symmetrically arranged aper-tures and extending the measurement range to±7.95μm via a two-wavelength(589 nm/600 nm)algorithm.This approach exploits ViT’s self-attention mechanism to model global characteristics of interference fringes.Unlike CNNs constrained by local convolutional kernels,the ViT significantly improves sensitivity to inter-ferogram periodicity.The simulation results demonstrate that the proposed method achieves a measurement accuracy of 5 nm(0.0083λ0)across the range of±7.95μm,while maintaining an accuracy exceeding 95%in the presence of Gaussian noise(SNR≥15 dB),Poisson noise(λ≥9 photons/pixel),and sub-mirror gap er-ror(Egap≤0.2)interference.Moreover,the detection speed shows significant improvement compared to the cross-correlation algorithm.This study establishes an accurate,robust framework for segmented mirror error detection,advancing high-precision astronomical observation. 展开更多
关键词 segmented mirror co-phasing piston errors ViT Young’s interference principles
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A Novel Feedforward Hybrid Active Noise Control System with Narrowband Frequency Adaptive Estimation and Error Separation
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作者 PANG Mingrui LIU Yifei LIU Jian 《Transactions of Nanjing University of Aeronautics and Astronautics》 2025年第5期638-647,共10页
The conventional feedforward hybrid active noise control(FFHANC)system combines the advantages of the feedforward narrowband active noise control(FFNANC)system and the feedforward broadband active noise control(FFBANC... The conventional feedforward hybrid active noise control(FFHANC)system combines the advantages of the feedforward narrowband active noise control(FFNANC)system and the feedforward broadband active noise control(FFBANC)system.To enhance its adaptive adjustment capability under frequency mismatch(FM)conditions,this paper introduces a narrowband frequency adaptive estimation module into the conventional FFHANC system.This module integrates an autoregressive(AR)model and a linear cascaded adaptive notch filter(LCANF),enabling accurate reference signal frequency estimation even under significant FM.Furthermore,in order to improve the coherence between narrowband and broadband components in the system’s error signal and its corresponding control filter for the conventional FFHANC system,this paper proposes an algorithm based on autoregressive bandpass filter bank(AR-BPFB)for error separation.Simulation results demonstrate that the proposed FFHANC system maintains robust performance under high FM conditions and effectively suppresses hybrid-band noise.The AR-BPFB algorithm significantly elevates the convergence speed of the FFHANC system. 展开更多
关键词 active noise control feedforward hybrid active noise control(FFHANC)system autoregressive(AR)model linear cascaded adaptive notch filter(LCANF) bandpass filter bank(BPFB) error separation
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FeatherGuard:A Data-Driven Lightweight Error Protection Scheme for DNN Inference on Edge Devices
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作者 Dong Hyun Lee Na Kyung Lee Young Seo Lee 《Computers, Materials & Continua》 2026年第2期2000-2016,共17页
There has been an increasing emphasis on performing deep neural network(DNN)inference locally on edge devices due to challenges such as network congestion and security concerns.However,as DRAM process technology conti... There has been an increasing emphasis on performing deep neural network(DNN)inference locally on edge devices due to challenges such as network congestion and security concerns.However,as DRAM process technology continues to scale down,the bit-flip errors in the memory of edge devices become more frequent,thereby leading to substantial DNN inference accuracy loss.Though several techniques have been proposed to alleviate the accuracy loss in edge environments,they require complex computations and additional parity bits for error correction,thus resulting in significant performance and storage overheads.In this paper,we propose FeatherGuard,a data-driven lightweight error protection scheme for DNN inference on edge devices.FeatherGuard selectively protects critical bit positions(that have a significant impact on DNN inference accuracy)against bit-flip errors,by considering various DNN characteristics(e.g.,data format,layer-wise weight distribution,actually stored logical values).Thus,it achieves high error tolerability during DNN inference.Since FeatherGuard reduces the bit-flip errors based on only a few simple arithmetic operations(e.g.,NOT operations)without parity bits,it causes negligible performance overhead and no storage overhead.Our experimental results show that FeatherGuard improves the error tolerability by up to 6667×and 4000×,compared to the conventional systems and the state-of-the-art error protection technique for edge environments,respectively. 展开更多
关键词 Edge AI DRAM reliability error protection bit-flip error deep neural networks
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Insights into Student Perceptions of Error Feedback and Improvement Preferences in Online Programming Education
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作者 Li Zhang Tianze Wang +1 位作者 Jing Jiang Yufei Zhou 《计算机教育》 2026年第3期176-189,共14页
Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a ... Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a solid data foundation when attempting to improve the error feedback mechanisms.This paper makes a survey of 834 students across various programming courses and investigates student perceptions of error feedback mechanisms on online programming platforms.It explores the effectiveness of existing feedback,student satisfaction,and preferences for potential improvements,focusing on automatic error localization and program repair mechanisms.Results reveal a significant portion of students are dissatisfied with current feedback due to its limited informativeness.Students also express a clear demand for stronger feedback mechanisms,such as error localization and repair hints.Nevertheless,they prefer feedback that subtly guides them toward solutions,rather than providing direct and explicit answers,valuing the opportunity to enhance their debugging skills.The findings suggest a need for balanced,educational-focused feedback mechanisms that aid learning while promoting independent problem-solving. 展开更多
关键词 error feedback Online programming education Program error localization Automated program repair
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Forecast errors of tropical cyclone track and intensity by the China Meteorological Administration from 2013 to 2022
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作者 Huanmujin Yuan Hong Wang +2 位作者 Yubin Li Kevin K.W.Cheung Zhiqiu Gao 《Atmospheric and Oceanic Science Letters》 2026年第1期72-77,共6页
This study presents a comprehensive evaluation of tropical cyclone(TC)forecast performance in the western North Pacific from 2013 to 2022,based on operational forecasts issued by the China Meteorological Administratio... This study presents a comprehensive evaluation of tropical cyclone(TC)forecast performance in the western North Pacific from 2013 to 2022,based on operational forecasts issued by the China Meteorological Administration.The analysis reveals systematic improvements in both track and intensity forecasts over the decade,with distinct error characteristics observed across various forecast parameters.Track forecast errors have steadily decreased,particularly for longer lead times,while error magnitudes have increased with longer forecast lead times.Intensity forecasts show similar progressive enhancements,with maximum sustained wind speed errors decreasing by 0.26 m/s per year for 120 h forecasts.The study also identifies several key patterns in forecast performance:typhoon-grade or stronger TCs exhibit smaller track errors than week or weaker systems;intensity forecasts systematically overestimate weaker TCs while underestimating stronger systems;and spatial error distributions show greater track inaccuracies near landmasses and regional intensity biases.These findings highlight both the significant advances in TC forecasting capability achieved through improved modeling and observational systems,and the remaining challenges in predicting TC changes and landfall behavior,providing valuable benchmarks for future forecast system development. 展开更多
关键词 Forecast error Tropical cyclone TRACK INTENSITY
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Total score of the computer vision syndrome questionnaire predicts refractive errors and binocular vision anomalies
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作者 Mosaad Alhassan Tasneem Samman +5 位作者 Hatoun Badukhen Muhamad Alrashed Balsam Alabdulkader Essam Almutleb Tahani Alqahtani Ali Almustanyir 《International Journal of Ophthalmology(English edition)》 2026年第1期90-96,共7页
AIM:To evaluate the efficacy of the total computer vision syndrome questionnaire(CVS-Q)score as a predictive tool for identifying individuals with symptomatic binocular vision anomalies and refractive errors.METHODS:A... AIM:To evaluate the efficacy of the total computer vision syndrome questionnaire(CVS-Q)score as a predictive tool for identifying individuals with symptomatic binocular vision anomalies and refractive errors.METHODS:A total of 141 healthy computer users underwent comprehensive clinical visual function assessments,including evaluations of refractive errors,accommodation(amplitude of accommodation,positive relative accommodation,negative relative accommodation,accommodative accuracy,and accommodative facility),and vergence(phoria,positive and negative fusional vergence,near point of convergence,and vergence facility).Total CVS-Q scores were recorded to explore potential associations between symptom scores and the aforementioned clinical visual function parameters.RESULTS:The cohort included 54 males(38.3%)with a mean age of 23.9±0.58y and 87 age-matched females(61.7%)with a mean age of 23.9±0.53y.The multiple regression model was statistically significant[R²=0.60,F=13.28,degrees of freedom(DF=17122,P<0.001].This indicates that 60%of the variance in total CVS-Q scores(reflecting reported symptoms)could be explained by four clinical measurements:amplitude of accommodation,positive relative accommodation,exophoria at distance and near,and positive fusional vergence at near.CONCLUSION:The total CVS-Q score is a valid and reliable tool for predicting the presence of various nonstrabismic binocular vision anomalies and refractive errors in symptomatic computer users. 展开更多
关键词 computer vision syndrome refractive errors ACCOMMODATION VERGENCE binocular vision SYMPTOMS
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Error Analysis of Geomagnetic Field Reconstruction Model Using Negative Learning for Seismic Anomaly Detection
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作者 Nur Syaiful Afrizal KhairulAdibYusof +5 位作者 Lokman Hakim Muhamad Nurul Shazana Abdul Hamid Mardina Abdullah Mohd Amiruddin Abd Rahman Syamsiah Mashohor Masashi Hayakawa 《Computers, Materials & Continua》 2026年第2期1338-1353,共16页
Detecting geomagnetic anomalies preceding earthquakes is a challenging yet promising area of research that has gained increasing attention in recent years.This study introduces a novel reconstruction-based modeling ap... Detecting geomagnetic anomalies preceding earthquakes is a challenging yet promising area of research that has gained increasing attention in recent years.This study introduces a novel reconstruction-based modeling approach enhanced by negative learning,employing a Bidirectional Long Short-Term Memory(BiLSTM)network explicitly trained to accurately reconstruct non-seismic geomagnetic signals while intentionally amplifying reconstruction errors for seismic signals.By penalizing the model for accurately reconstructing seismic anomalies,the negative learning approach effectively magnifies the differences between normal and anomalous data.This strategic differentiation enhances the sensitivity of the BiLSTM network,enabling improved detection of subtle geomagnetic anomalies that may serve as earthquake precursors.Experimental validation clearly demonstrated statistically significant higher reconstruction errors for seismic signals compared to non-seismic signals,confirmed through the Mann-Whitney U test with a p-value of 0.0035 for Root Mean Square Error(RMSE).These results provide compelling evidence of the enhanced anomaly detection capability achieved through negative learning.Unlike traditional classification-based methods,negative learning explicitly encourages sensitivity to subtle precursor signals embedded within complex geomagnetic data,establishing a robust basis for further development of reliable earthquake prediction methods. 展开更多
关键词 error analysis geomagnetic field BiLSTM model negative learning earthquake precursor
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Error Correction Method of Ultra-short-term Prediction Based on Load Peak-valley Characteristics for Wind Farm Cluster
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作者 Mao Yang Yunfeng Guo 《CSEE Journal of Power and Energy Systems》 2026年第1期258-270,共13页
In recent years,the global installed capacity of wind power has grown rapidly,making the enhancement of wind power prediction accuracy crucial for facilitating the integration and consumption of renewable energy.Curre... In recent years,the global installed capacity of wind power has grown rapidly,making the enhancement of wind power prediction accuracy crucial for facilitating the integration and consumption of renewable energy.Current research on ultra-short-term wind power prediction often overlooks load characteristics,resulting in an inability to adequately address grid connection requirements and load dispatching demands across different time periods.To address this limitation,this study proposes a novel approach to ultra-short-term wind power prediction error correction that incorporates load peak-valley characteristics.The methodology involves three key steps:first,deriving interannual prediction error characteristics from ultra-short-term prediction results of wind farm clusters;second,establishing error correction intervals for load peak and valley periods,calculating corresponding correction coefficients,and analyzing the impact of varying correction radii on the final results;third,validating the proposed method through empirical analysis of wind farm clusters in three northeastern provinces.The results demonstrate that this approach not only improves wind power prediction accuracy but also significantly reduces the occurrence of harmful error days,thereby better meeting the operational requirements of power system dispatch. 展开更多
关键词 Correction interval correction radius error correction load peak-valley characteristics
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Rateless Polar Codes with Unequal Error Protection Property
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作者 Cui Chen Xiang Wei +1 位作者 Ma Siwei Guo Qing 《China Communications》 2026年第1期10-23,共14页
Mobile communications are reaching out to every aspect of our daily life,necessitating highefficiency data transmission and support for diverse data types and communication scenarios.Polar codes have emerged as a prom... Mobile communications are reaching out to every aspect of our daily life,necessitating highefficiency data transmission and support for diverse data types and communication scenarios.Polar codes have emerged as a promising solution due to their outstanding error-correction performance and low complexity.Unequal error protection(UEP)involves nonuniform error safeguarding for distinct data segments,achieving a fine balance between error resilience and resource allocation,which ultimately enhancing system performance and efficiency.In this paper,we propose a novel class of UEP rateless polar codes.The codes are designed based on matrix extension of polar codes,and elegant mapping and duplication operations are designed to achieve UEP property while preserving the overall performance of conventional polar codes.Superior UEP performance is attained without significant modifications to conventional polar codes,making it straightforward for compatibility with existing polar codes.A theoretical analysis is conducted on the block error rate and throughput efficiency performance.To the best of our knowledge,this work provides the first theoretical performance analysis of UEP rateless polar codes.Simulation results show that the proposed codes significantly outperform existing polar coding schemes in both block error rate and throughput efficiency. 展开更多
关键词 matrix extension polar codes rateless coding unequal error protection
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Research on ultraprecision turning and profile-error compensation technology for multi-axis linkage
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作者 Xipeng Guo Jiabin Yuan +1 位作者 Wei Shi Shaohui Yin 《Nanotechnology and Precision Engineering》 2026年第1期60-69,共10页
In an ultraprecision turning process for small-diameter optical aspheric workpieces,tool-profile errors induce mid-frequency errors in the workpiece profile,limiting further improvements in precision.In this study,an ... In an ultraprecision turning process for small-diameter optical aspheric workpieces,tool-profile errors induce mid-frequency errors in the workpiece profile,limiting further improvements in precision.In this study,an XZB three-axis linkage ultraprecision machining method is proposed,and the effects of tool-center errors are analyzed.To address residual errors in Z-direction profile-error compensation,a workpiece normal-profile-error compensation method is proposed.After XZB three-axis linkage turning and compensation,the workpiece profile error(PV)reaches 0.086μm,surpassing the precision of XZ two-axis machining,and mid-frequency errors are reduced.Compared with Z-direction profile-error compensation,which results in a profile error of 0.092μm,normal-profile-error compensation reduces PV to 0.047μm,considerably improving aspheric accuracy.Experimental results demonstrate that XZB three-axis linkage machining significantly improves the aspheric workpiece profile,enhancing both its accuracy and surface quality.This method reduces mid-frequency errors,and the subsequent application of normal-profile-error compensation further refines the profile,achieving higher overall accuracy. 展开更多
关键词 Aspheric workpiece Ultraprecision turning XZB three-axis linkage Normal error compensation
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Retaining local chemical effects:An error cancellation strategy for calculating standard gas-phase enthalpy of formation
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作者 Rui Liu Chaoyang Zhang +2 位作者 Linyuan Wang Zhiyu Huang Jian Liu 《Defence Technology(防务技术)》 2026年第1期172-179,共8页
Conventional error cancellation approaches separate molecules into smaller fragments and sum the errors of all fragments to counteract the overall computational error of the parent molecules.However,these approaches m... Conventional error cancellation approaches separate molecules into smaller fragments and sum the errors of all fragments to counteract the overall computational error of the parent molecules.However,these approaches may be ineffective for systems with strong localized chemical effects,as fragmenting specific substructures into simpler chemical bonds can introduce additional errors instead of mitigating them.To address this issue,we propose the Substructure-Preserved Connection-Based Hierarchy(SCBH),a method that automatically identifies and freezes substructures with significant local chemical effects prior to molecular fragmentation.The SCBH is validated by the gas-phase enthalpy of formation calculation of CHNO molecules.Therein,based on the atomization scheme,the reference and test values are derived at the levels of Gaussian-4(G4)and M062X/6-31+G(2df,p),respectively.Compared to commonly used approaches,SCBH reduces the average computational error by half and requires only15%of the computational cost of G4 to achieve comparable accuracy.Since different types of local effect structures have differentiated influences on gas-phase enthalpy of formation,substituents with strong electronic effects should be retained preferentially.SCBH can be readily extended to diverse classes of organic compounds.Its workflow and source code allow flexible customization of molecular moieties,including azide,carboxyl,trinitromethyl,phenyl,and others.This strategy facilitates accurate,rapid,and automated computations and corrections,making it well-suited for high-throughput molecular screening and dataset construction for gas-phase enthalpy of formation. 展开更多
关键词 Gas-phase enthalpy of formation error cancellation Quantum chemical High throughput
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Acute liver failure caused by amino acid or organic acid related inborn errors of metabolism
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作者 Ying Zhou Chi Chen Xin Yang 《Hepatobiliary & Pancreatic Diseases International》 2026年第1期112-114,共3页
Inborn errors of metabolism(IEMs)are a large group of disorders resulting from deficient activities in several metabolic pathways due to the dysfunction of a distinct enzyme associated with a biochemical pathway[1,2].... Inborn errors of metabolism(IEMs)are a large group of disorders resulting from deficient activities in several metabolic pathways due to the dysfunction of a distinct enzyme associated with a biochemical pathway[1,2].Toxic intermediates will be produced due to the dysfunction of biochemical pathways.The liver is responsible for many essential metabolic processes,therefore it becomes one of the most severely affected organ by metabolic diseases[3].Early onset of liver disorders in IEMs includes jaundice,hepatomegaly,splenomegaly,ascites,hepatic encephalopathy,and liver failure[4].In infants and young children under 3 years old with acute liver failure(ALF),IEMs account for 18.9%-43%[5]. 展开更多
关键词 biochemical pathway toxic intermediates metabolic diseases early acute liver failure inborn errors metabolism iems organic acid dysfunction distinct enzyme metabolic processestherefore metabolic pathways
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Perioperative management of pediatric patients with inborn errors of metabolism during liver transplantation
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作者 Susan Paulin Akila Rajakumar +2 位作者 Jagadeesh Menon Naresh Shanmugam Mohamed Rela 《World Journal of Transplantation》 2026年第1期91-102,共12页
Inborn errors of metabolism(IEM)are rare disorders,most are liver-based with liver transplantation(LT)emerging as an effective cure in the pediatric population.LT has been shown to offer a cure or deter disease progre... Inborn errors of metabolism(IEM)are rare disorders,most are liver-based with liver transplantation(LT)emerging as an effective cure in the pediatric population.LT has been shown to offer a cure or deter disease progression and provide symptomatic improvement in patients with IEM.Each metabolic disorder is unique,with the missing enzyme or transporter protein causing substrate deficiency or toxic byproduct production.Knowledge about the distribution of deficient enzymes,the percentage of enzymes replaced by LT,and the extent of extrahepatic involvement helps anticipate and manage complications in the perioperative period.Most patients have multisystem involvement and can be on complex dietary regimens.Metabolic decompensation can be triggered due to the stress response to surgery,fasting and other unanticipated complications perioperatively.Thus,a multidisciplinary team’s input including those from metabolic specialists is essential to develop disease and patient-specific strategies for the perioperative management of these patients during LT.In this review,we outline the classification of IEM,indications for LT along with potential benefits,basic metabolic defects and their implications,details of extrahepatic involvement and perioperative management strategies for LT in children with some of the commonly presenting IEM,to assist anesthesiologists handling this cohort of patients. 展开更多
关键词 Inborn errors of metabolism Anaesthesia for paediatric liver transplantation Metabolic crisis Hyperammonemia in paediatric liver transplantation Perioperative care in metabolic liver diseases
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