Behavioral adjustment plays an important role in the treatment and relapse of drug addiction. Nonetheless,few studies have examined behavioral adjustment and its plasticity following error commission in methamphetamin...Behavioral adjustment plays an important role in the treatment and relapse of drug addiction. Nonetheless,few studies have examined behavioral adjustment and its plasticity following error commission in methamphetamine（METH） dependence, which is detrimental to human health. Thus, we investigated the behavioral adjustment performance following error commission in long-term METH addicts and how it varied with the application of repetitive transcranial magnetic stimulation（r TMS） of the left dorsolateral prefrontal cortex（DLPFC）. Twenty-nine male long-term METH addicts（for [ 3 years） were randomly assigned to high-frequency（10 Hz, n = 15） or sham（n = 14） r TMS of the left DLPFC during a two-choice oddball task. Twenty-six age-matched, healthy male adults participated in the two-choice oddball task pretest to establish normal performance for comparison. The results showed that 10 Hz r TMS over the left DLPFC significantly decreased the post-error slowing effect in response times of METH addicts. In addition, the 10 Hz r TMS intervention remarkably reduced the reaction times during post-error trials but not post-correct trials. While the 10 Hz r TMS group showed a more pronounced post-error slowing effect than the healthy participants during the pretest, the posterror slowing effect in the posttest of this sample was similar to that in the healthy participants. These results suggest that high-frequency r TMS over the left DLPFC is a useful protocol for the improvement of behavioral adjustment after error commission in long-term METH addicts.展开更多
Aiming at a comprehensive assessment of energy-saving retrofitting effect on existing buildings,a calculation method is developed to adjust energy-saving quantity in standard condition for comparison under the same co...Aiming at a comprehensive assessment of energy-saving retrofitting effect on existing buildings,a calculation method is developed to adjust energy-saving quantity in standard condition for comparison under the same conditions. A mathematical model,method theory and calculation steps are given. Error analysis results show that this method can be applied accurately to practical engineering projects. In a case study of energy-saving quantity assessment before and after retrofitting on a certain hospital in Shanghai,with energy simulation software TRNSYS,detailed application of this method is introduced and analyzed. The method is applied to the case of energy-saving quantity assessment to a hospital in Shanghai before and after retrofitting with the energy simulation software TRNSYS.展开更多
基金supported by the National Natural Science Foundation of China (31371042, 31400906 and 31600886)the Key Program of the Higher Education Institutions of Henan Province, China (17AJ90002)
文摘Behavioral adjustment plays an important role in the treatment and relapse of drug addiction. Nonetheless,few studies have examined behavioral adjustment and its plasticity following error commission in methamphetamine（METH） dependence, which is detrimental to human health. Thus, we investigated the behavioral adjustment performance following error commission in long-term METH addicts and how it varied with the application of repetitive transcranial magnetic stimulation（r TMS） of the left dorsolateral prefrontal cortex（DLPFC）. Twenty-nine male long-term METH addicts（for [ 3 years） were randomly assigned to high-frequency（10 Hz, n = 15） or sham（n = 14） r TMS of the left DLPFC during a two-choice oddball task. Twenty-six age-matched, healthy male adults participated in the two-choice oddball task pretest to establish normal performance for comparison. The results showed that 10 Hz r TMS over the left DLPFC significantly decreased the post-error slowing effect in response times of METH addicts. In addition, the 10 Hz r TMS intervention remarkably reduced the reaction times during post-error trials but not post-correct trials. While the 10 Hz r TMS group showed a more pronounced post-error slowing effect than the healthy participants during the pretest, the posterror slowing effect in the posttest of this sample was similar to that in the healthy participants. These results suggest that high-frequency r TMS over the left DLPFC is a useful protocol for the improvement of behavioral adjustment after error commission in long-term METH addicts.
基金Project(2006BAJ03A10) supported by the National Key Technologies R & D Program of China
文摘Aiming at a comprehensive assessment of energy-saving retrofitting effect on existing buildings,a calculation method is developed to adjust energy-saving quantity in standard condition for comparison under the same conditions. A mathematical model,method theory and calculation steps are given. Error analysis results show that this method can be applied accurately to practical engineering projects. In a case study of energy-saving quantity assessment before and after retrofitting on a certain hospital in Shanghai,with energy simulation software TRNSYS,detailed application of this method is introduced and analyzed. The method is applied to the case of energy-saving quantity assessment to a hospital in Shanghai before and after retrofitting with the energy simulation software TRNSYS.
