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Learning by Comparing:Effects of Cues Focusing on Chinese-Speaking Learners’Acquisition of English Articles
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作者 Mei Yang Qiying Guo Xiaomeng Yan 《Chinese Journal of Applied Linguistics》 2026年第1期57-75,160,共20页
This study examines whether and how cues focusing enhances Chinese-speaking English learners’engagement in comparison,thereby facilitating their acquisition of English articles within xu-based comparative continuatio... This study examines whether and how cues focusing enhances Chinese-speaking English learners’engagement in comparison,thereby facilitating their acquisition of English articles within xu-based comparative continuation writing tasks.Fifty English majors from a Chinese university were randomly assigned to three groups and each group was required to complete a comparative continuation task with one of three conditions:paired cues(cues presented in pairs),randomized cues(cues presented in random order),or implicit cues(no explicit cues provided).All participants undertook pretests,posttests,and delayed tests on English article knowledge,and ten of them volunteered to take follow-up interviews.The results indicate that:1)paired cues were more effective than randomized or implicit cues in promoting the acquisition of English articles;and 2)learners in the paired cues condition produced more target-like article usage in their continuation writings compared to those in the other two conditions.The effectiveness of paired cues is attributed to an enhanced contrast effect,which prompts learners to identify similarities and differences between cues within each pair,relates cue explanations and examples with actual article usage in the reading text,and reflects upon and compares their own article productions against those in the provided reading text.The study concludes that the process of learning through continuation is fundamentally supported by learners’capacity for comparison,reinforcing its role as a core element of xu-competence. 展开更多
关键词 comparison cues focusing acquisition of English articles xu-argument
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Case studies of ion focusing in the downstream region of a modeled low Earth orbit spacecraft
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作者 Nizam Ahmad Hideyuki Usui +4 位作者 Yohei Miyake Slamet Supriadi Hanif Fakhrurroja Hilman Syaeful Alam Harry Bangkit 《Earth and Planetary Physics》 2026年第1期136-143,共8页
The effect of plasma and charged particle interaction with spacecraft in a low Earth orbit(LEO)environment leads to ion focusing and the formation of an ion void in the downstream region as a result of charging.Simula... The effect of plasma and charged particle interaction with spacecraft in a low Earth orbit(LEO)environment leads to ion focusing and the formation of an ion void in the downstream region as a result of charging.Simulations and investigations using a fixed potential imposed on the spacecraft showed the nonsignificance of geophysical parameter changes to ion focusing.Variation of the temperature ratio(T_(r))contributed only to local ion focusing and manifested as two-ion streamers dispersed at the upper and lower edges of the spacecraft-the outermost layers of the satellite structure at the top and bottom,respectively.A simulation involving changing the ambient plasma density(N_(p))also showed the formation of local ion focusing,in which ions were more concentrated as the density increased.Furthermore,auroral electron density(N_(ae))variation had no clear impact on ion focusing,as indicated by static two-ion structures in the wake field.However,variation of the object potential(ϕ)strongly affected ion focusing formation,leading to distortion of the initial ion void region behind the spacecraft.The formation of ion focusing in this study was subject to the electric field produced by the object potential and the ambipolar electric field resulting from plasma expansion in the downstream region. 展开更多
关键词 ion focusing spacecraft potential low Earth orbit environment
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Therapeutic effects of low-intensity transcranial focused ultrasound stimulation on ischemic stroke in rats:An in vivo evaluation using electrical impedance tomography
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作者 Jiecheng Guo Sixuan He +4 位作者 Li Yan Lei Wang Xuetao Shi Huijing Hu Le Li 《Neural Regeneration Research》 2026年第3期1183-1190,共8页
Although previous studies have demonstrated that transcranial focused ultrasound stimulation protects the ischemic brain,clear criteria for the stimulation time window and intensity are lacking.Electrical impedance to... Although previous studies have demonstrated that transcranial focused ultrasound stimulation protects the ischemic brain,clear criteria for the stimulation time window and intensity are lacking.Electrical impedance tomography enables real-time monitoring of changes in cerebral blood perfusion within the ischemic brain,but investigating the feasibility of using this method to assess post-stroke rehabilitation in vivo remains critical.In this study,ischemic stroke was induced in rats through middle cerebral artery occlusion surgery.Transcranial focused ultrasound stimulation was used to treat the rat model of ischemia,and electrical impedance tomography was used to measure impedance during both the acute stage of ischemia and the rehabilitation stage following the stimulation.Electrical impedance tomography results indicated that cerebral impedance increased after the onset of ischemia and decreased following transcranial focused ultrasound stimulation.Furthermore,the stimulation promoted motor function recovery,reduced cerebral infarction volume in the rat model of ischemic stroke,and induced the expression of brain-derived neurotrophic factor in the ischemic brain.Our results also revealed a significant correlation between the impedance of the ischemic brain post-intervention and improvements in behavioral scores and infarct volume.This study shows that daily administration of transcranial focused ultrasound stimulation for 20 minutes to the ischemic hemisphere 24 hours after cerebral ischemia enhanced motor recovery in a rat model of ischemia.Additionally,our findings indicate that electrical impedance tomography can serve as a valuable tool for quantitatively evaluating rehabilitation after ischemic stroke in vivo.These findings suggest the feasibility of using impedance data collected via electrical impedance tomography to clinically assess the effects of rehabilitatory interventions for patients with ischemic stroke. 展开更多
关键词 animal model brain stimulation electrical impedance tomography evaluation impedance noninvasive treatment real-time monitoring REHABILITATION STROKE transcranial focused ultrasound stimulation
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CIDPEX2026 focus生活用纸和卫生用品国际论坛日程抢先一览
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《生活用纸》 2026年第2期9-11,共3页
第三十三届生活用纸国际科技展览会将于2026年4月在南京拉开帷幕,4月13—14日举办focus国际论坛,4月15—17日举办展览会。CIDPEX展会开展前举办的国际论坛,以行业实战需求为导向,以全球化、前瞻性视角,对“焦”生活用纸和卫生用品两大行... 第三十三届生活用纸国际科技展览会将于2026年4月在南京拉开帷幕,4月13—14日举办focus国际论坛,4月15—17日举办展览会。CIDPEX展会开展前举办的国际论坛,以行业实战需求为导向,以全球化、前瞻性视角,对“焦”生活用纸和卫生用品两大行业,集“聚”全球业内专家,“聚”焦高关注度话题,洞察、解析、对话、研讨,为国内外企业搭建开放共享、协作共赢的专业交流平台。 展开更多
关键词 生活用纸 CIDPEX2026 卫生用品 focus国际论坛
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朱砂七化学成分的UHPLC-Q Exactive Focus MS分析
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作者 后亚芳 任慧 +4 位作者 崔小敏 鲁文静 胡静 曲彤 陈志永 《中药材》 北大核心 2025年第5期1186-1192,共7页
目的:基于UHPLC-Q Exactive Focus MS技术对朱砂七的化学成分进行快速识别和鉴定。方法:采用Thermo Accucore aQ RP18色谱柱(150 mm×2.1 mm,2.6μm);甲醇-0.1%甲酸水溶液为流动相,梯度洗脱;流速0.3 mL/min;柱温30℃。采用电喷雾离... 目的:基于UHPLC-Q Exactive Focus MS技术对朱砂七的化学成分进行快速识别和鉴定。方法:采用Thermo Accucore aQ RP18色谱柱(150 mm×2.1 mm,2.6μm);甲醇-0.1%甲酸水溶液为流动相,梯度洗脱;流速0.3 mL/min;柱温30℃。采用电喷雾离子源,正、负离子模式扫描,扫描范围为m/z 80~1200。结果:从朱砂七中共解析出53个化学成分,包括蒽醌类17个,色原酮类5个,二苯乙烯类6个,萘苷类4个,黄烷类4个,酚酸类15个,其他类2个。结论:该方法可快速对朱砂七中化学成分进行定性分析,为后续朱砂七药效物质研究及质量评价提供依据。 展开更多
关键词 朱砂七 UHPLC-Q Exactive focus MS 蒽醌类 色原酮类 二苯乙烯类
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Low-Intensity Focused Ultrasound Ameliorates Cisplatin-Induced Cognitive Impairment by Attenuating Hippocampal Neuroinflammation and Enhancing Synaptic Plasticity in Rats 被引量:1
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作者 Xiaowei Han Hagiwara Akifumi +8 位作者 Pin Lv Jiahuan Liu Xiaowei Huang Renyuan Liu Xiaojing Long Yang Liu Jiangong Zhang Guolin Ma Bing Zhang 《iRADIOLOGY》 2025年第2期152-167,共16页
Background:Platinum can cause chemotherapy-related cognitive impairment.Low-intensity focused ultrasound(LIFUS)is a promising noninvasive physical stimulation method with a unique advantage in neurological rehabilitat... Background:Platinum can cause chemotherapy-related cognitive impairment.Low-intensity focused ultrasound(LIFUS)is a promising noninvasive physical stimulation method with a unique advantage in neurological rehabilitation.We aimed to investigate whether LIFUS can alleviate cisplatin-induced cognitive impairment in rats and explore the related neuropatho-logical mechanisms.Methods:After confirming the target position for LIFUS treatment in 18 rats,64 rats were randomly divided into four groups:control,model,sham,and LIFUS groups.Before and after LIFUS treatment,detailed biological behavioral assessments and magnetic resonance imaging were performed.Finally,the rats were euthanized,and relevant histopathological and molecular biological experiments were conducted and analyzed.Results:In the Morris water maze,the model group showed fewer platform crossings(1.250.93 vs.5.691.58),a longer escape latency(41.6536.55 s vs.6.382.11 s),and a lower novel object recognition index(29.7711.83 vs.83.695.67)than the control group.LIFUS treatment improved these metrics,with more platform crossings(3.130.34),a higher recognition index(65.588.71),and a shorter escape latency(6.452.27 s).Longitudinal analysis of the LIFUS group further confirmed these improvements.Neuroimaging revealed significant differences in diffusion tensor imaging metrics of specific brain regions pre-and post-LIFUS.Moreover,neuropathology showed higher dendritic spine density,less myelin loss,fewer apoptotic cells,more synapses,and less mitochondrial autophagy after LIFUS treatment.The neuroimaging indicators were correlated with behavioral improvements,highlighting the potential of LIFUS for alleviating cognitive impairment(as demonstrated through imaging and analysis).Our investigation of the molecular biological mechanisms revealed distinct protein expression patterns in the hippocampus and its subregions.In the model group,glial fibrillary acidic protein(GFAP)and ionized calcium-binding adaptor molecule 1(IBA1)expression levels were elevated across the hippocampus,whereas neuronal nuclei(NeuN)expression was reduced.Subregional analysis revealed higher GFAP and IBA1 and lower NeuN,especially in the dentate gyrus subregion.Moreover,positive cell areas were larger in the cornu ammonis(CA)1,CA2,CA3,and dentate gyrus regions.In the CA2 and CA3,significant differences among the groups were observed in GFAP-positive cell counts and areas,and there were variations in NeuN expression.Conclusions:Our results suggest that LIFUS can reverse cisplatin-induced cognitive impairments.The neuroimaging findings were consistent with the behavioral and histological results and suggest a neuropathological basis that supports further research into the clinical applications of LIFUS.Furthermore,LIFUS appeared to enhance the plasticity of neuronal synapses in the rat hippocampus and reduce hippocampal inflammation.These findings highlight the clinical potential of LIFUS as an effective,noninvasive therapeutic strategy and monitoring tool for chemotherapy-induced cognitive deficits. 展开更多
关键词 cognitive impairment diffusion tensor imaging low-intensity focused ultrasound molecular biology mechanism NEUROPATHOLOGY
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基于UPLC-Q-Exactive Focus MS/MS和网络药理学的枣仁安神胶囊治疗失眠的潜在质量标志物预测
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作者 曲彤 张红 +6 位作者 李宁 鲁文静 崔小敏 胡静 梁超 任慧 陈志永 《药物评价研究》 北大核心 2025年第11期3206-3225,共20页
目的运用超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UPLC-Q-Exactive Focus MS/MS)技术鉴定枣仁安神胶囊化学成分,结合网络药理学和分子对接对枣仁安神胶囊治疗失眠的质量标志物(Q-Marker)进行预测。方法采用UPLC-Q-Exactive Focus... 目的运用超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UPLC-Q-Exactive Focus MS/MS)技术鉴定枣仁安神胶囊化学成分,结合网络药理学和分子对接对枣仁安神胶囊治疗失眠的质量标志物(Q-Marker)进行预测。方法采用UPLC-Q-Exactive Focus MS/MS技术在正、负离子模式下对枣仁安神胶囊中化学成分进行定性分析;将所得成分导入SwissADME数据库检索成分靶点;利用GeneCards、OMIM数据库收集失眠相关疾病靶点,取交集后利用Cytoscape 3.7.2软件构建“成分-疾病-靶点”网络,STRING数据库建立蛋白质-蛋白质相互作用(PPI)网络并筛选核心成分与核心靶点。利用DAVID数据库对共同靶点进行基因本体(GO)和京都基因与基因组百科全书(KEGG)通路富集分析,借助分子对接预测核心成分和关键靶点的结合能力,初步探索枣仁安神胶囊的Q-Marker。结果通过UPLC-Q-Exactive Focus MS/MS共鉴定了枣仁安神胶囊中147种化学成分,结合数据库得到35个具有作用靶点的活性成分,644个与失眠相关靶点。其中,戈米辛E、表丹参隐螺内酯、五味子酯乙、五味子醇甲、五味子醇乙、五味子酯甲、木兰箭毒碱为枣仁安神胶囊治疗失眠的核心成分,蛋白激酶B(AKT1)、肿瘤坏死因子(TNF)、信号传导子及转录激活子3(STAT3)、B细胞淋巴瘤/白血病-2蛋白(BCL2)、胱天蛋白酶3(CASP3)为枣仁安神胶囊治疗失眠的核心靶点。作用于失眠与神经退行性变的途径、生长激素的合成、趋化因子信号通路等15条信号通路。分子对接结果表丹参隐螺内酯、戈米辛E、五味子醇乙、木兰箭毒碱4个核心成分与相关核心靶点的结合活性较好可作为枣仁安神胶囊的Q-Marker。结论预测枣仁安神胶囊可能通过表丹参隐螺内酯、戈米辛E、五味子醇乙、木兰箭毒碱等关键成分,作用于AKT1、TNF、STAT3和BCL2等靶点,通过干预neurodegeneration-multiple diseases、Chemokine、FoxO等通路发挥治疗失眠的作用。 展开更多
关键词 枣仁安神胶囊 超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UPLC-Q Exactive focus MS/MS) 网络药理学 分子对接 质量标志物 表丹参隐螺内酯 戈米辛E 五味子醇乙 木兰箭毒碱
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Muscular activity of hamstrings under attentional focus instructions:an electromyography based study
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作者 Ayse Nur Ay Gul Mustafa Zahid Yildiz 《Translational Exercise Biomedicine》 2025年第4期326-334,共9页
Objectives:The effect of attentional focusing on muscular activities and motor skills has been well established.It is known that internal focusing(on body movement or the action itself)results in increased muscular ac... Objectives:The effect of attentional focusing on muscular activities and motor skills has been well established.It is known that internal focusing(on body movement or the action itself)results in increased muscular activity.However,external focusing(on apparatus or the effect of action)results in decreased motor responses.In this study,the impact of attentional focusing has been investigated by exploring the three major components of hamstrings:the semitendinosus,the semimembranosus and the biceps femoris via EMG activity on 20 amateur football players during leg curl exercises.Methods:To measure muscle activities of the participants,Integrated EMG(IEMG)was calculated on the data’s MVC values.Paired sampled t-tests with Bonferroni correction(α=0.0167)were performed on the average IEMG values to determine if there is a significant difference between participants’muscles activities under various attentional focus conditions.Results:The results showed that the semimembranosus exhibited significantly reduced activity under both external(p=0.0124)and internal focus(p=0.0008),while the semitendinosus displayed a small but non-significant reduction under external focus(p=0.0355>0.0167).The biceps femoris showed no significant motor response regarding change between attentional focus instructions.Conclusions:This study improves understanding of the mind-muscle connection by showing muscle-specific differences in attentional focus effects,with semimembranosus being most responsive. 展开更多
关键词 attentional focus mind-muscle connection ELECTROMYOGRAPHY HAMSTRINGS
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Sub-diffraction-limited focusing laser pulses at ultrahigh intensity via near-critical-density hollow plasma fibers
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作者 Tianqi Xu Zhuo Pan +12 位作者 Ying Gao Yulan Liang Shirui Xu Qingfan Wu Tan Song Yujia Zhang Haoran Chen Qihang Han Chenghao Hua Ziyang Peng Ke Chen Xuan Liu Wenjun Ma 《Advanced Photonics Nexus》 2025年第6期64-71,共8页
Ultra-intense electromagnetic fields exceeding 10^(23)W∕cm^(2)are enabling breakthroughs in compact laser-driven particle accelerators and revealing new quantum electrodynamics(QED)phenomena.However,conventional lase... Ultra-intense electromagnetic fields exceeding 10^(23)W∕cm^(2)are enabling breakthroughs in compact laser-driven particle accelerators and revealing new quantum electrodynamics(QED)phenomena.However,conventional laser-focusing methods face considerable engineering challenges and require substantial costs.Focusing schemes utilizing plasma optics can produce sub-micrometer focus spots beyond the diffraction limit and substantially enhance the peak intensity;however,owing to significant energy dissipation,they may fail to simultaneously increase the laser fluence.To address these challenges,we propose a focusing scheme employing a near-critical-density hollow plasma fiber(HPF)that utilizes graded refractive index dynamics to boost both laser peak intensity and fluence at the same time.Three-dimensional particle-in-cell simulations demonstrate the HPF’s capability to focus a 4.5-μm-diameter Gaussian beam to a sub-diffraction-limited 0.6-μm-diameter spot.The peak intensity and laser fluence can be enhanced by factors of 22 and 10,respectively,marking a substantial improvement over existing plasma-based focusing schemes.Furthermore,the proposed scheme exhibits wide-range parameter adaptation and high robustness,making it suitable for direct implementation in PW-class ultra-intense laser experiments. 展开更多
关键词 plasma optics laser focusing intensity enhancement
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The Impact of Vicarious Abusive Supervision on Third-Party’s Self-Efficacy and Task Performance:The Moderating Role of Promotion Focus in Unethical Leadership Contexts
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作者 LI Yuxuan ZHOU Yuqin +2 位作者 MI Shufei HUANG Hancheng CHEN Wenhua 《Chinese Business Review》 2025年第2期69-85,共17页
Drawing upon self-determination theory,this study examines the effects of vicarious abusive supervision on third-party’s self-efficacy and task performance within organizational contexts.Data were collected via surve... Drawing upon self-determination theory,this study examines the effects of vicarious abusive supervision on third-party’s self-efficacy and task performance within organizational contexts.Data were collected via surveys from 337 employees across diverse organizations.The results indicate that vicarious abusive supervision significantly undermines both self-efficacy and task performance among employees who are indirectly exposed to such behavior but not directly targeted.Furthermore,self-efficacy serves as a mediator between vicarious abusive supervision and task performance;however,this mediating effect is attenuated for employees with a high promotion focus.These findings provide valuable theoretical and practical insights,particularly in the domain of organizational behavior,by emphasizing the critical role of promotion focus in mitigating the negative effects of vicarious abusive supervision.This research contributes to the organizational behavior literature by shifting the focus from the traditional supervisor-subordinate dynamic to a third-party perspective,thereby enriching our understanding of how vicarious abusive supervision impacts employees within organizational settings.The study underscores the importance of self-efficacy and promotion focus as key factors in unethical leadership contexts. 展开更多
关键词 vicarious abusive supervision task performance SELF-EFFICACY promotion focus third-party
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Systematic Review of Phase Aberration Correction Algorithms for Transcranial Focused Ultrasound
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作者 Mingyu Wang Zhouyang Xu Bingbing Cheng 《iRADIOLOGY》 2025年第1期26-46,共21页
Transcranial focused ultrasound(tFUS)is an emerging modality with strong potential for non-invasively treating brain disorders.However,the inhomogeneity and complex structure of the skull induce substantial phase aber... Transcranial focused ultrasound(tFUS)is an emerging modality with strong potential for non-invasively treating brain disorders.However,the inhomogeneity and complex structure of the skull induce substantial phase aberrations and pressure attenuation;these can distort and shift the acoustic focus,thus hindering the efficiency of tFUS therapy.To achieve effective treatments,phased array transducers combined with aberration correction algorithms are commonly implemented.The present report aims to provide a comprehensive review of the current methods used for tFUS phase aberration correction.We first searched the PubMed and Web of Science databases for studies on phase aberration correction algorithms,identifying 54 articles for review.Relevant information,including the principles of algorithms and refocusing performances,were then extracted from the selected articles.The phase correction algorithms involved two main steps:acoustic field estimation and transmitted pulse adjustment.Our review identified key benchmarks for evaluating the effectiveness of these algorithms,each of which was used in at least three studies.These benchmarks included pressure and intensity,positioning error,focal region size,peak sidelobe ratio,and computational efficiency.Algorithm performances varied under different benchmarks,thus highlighting the importance of application-specific algorithm selection for achieving optimal tFUS therapy outcomes.The present review provides a thorough overview and comparison of various phase correction algorithms,and may offer valuable guidance to tFUS researchers when selecting appropriate phase correction algorithms for specific applications. 展开更多
关键词 brain disorders phase correction skull aberration transcranial focused ultrasound
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Energy focusing of flexural waves via algorithmically optimized coding metasurface lenses
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作者 Zi-Rui Wang Di-Chao Chen +1 位作者 Rui Hong Da-Jian Wu 《Chinese Physics B》 2025年第9期277-282,共6页
Efficient elastic wave focusing is crucial in materials and physical engineering.Elastic coding metasurfaces,which are innovative planar artificial structures,show great potential for use in the field of wave focusing... Efficient elastic wave focusing is crucial in materials and physical engineering.Elastic coding metasurfaces,which are innovative planar artificial structures,show great potential for use in the field of wave focusing.However,elastic coding lenses(ECLs)still suffer from low focusing performance,thickness comparable to wavelength,and frequency sensitivity.Here,we consider both the structural and material properties of the coding unit,thus realizing further compression of the thickness of the ECL.We chose the simplest ECL,which consists of only two encoding units.The coding unit 0 is a straight structure constructed using a carbon fiber reinforced composite material,and the coding unit 1 is a zigzag structure constructed using an aluminum material,and the thickness of the ECL constructed using them is only 1/8 of the wavelength.Based on the theoretical design,the arrangement of coding units is further optimized using genetic algorithms,which significantly improves the focusing performance of the lens at different focus and frequencies.This study provides a more effective way to control vibration and noise in advanced structures. 展开更多
关键词 coding metasurface elastic wave focusing genetic algorithm
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A tunable acoustic metasurface via one-dimensional mechanical adjustment for real-time focusing
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作者 Jie Hu Mengqi Jiang +1 位作者 Rui Zang Yuhang Qian 《Chinese Physics B》 2025年第10期399-404,共6页
Adjustable or programmable metamaterials offer versatile functions,while the complex multi-dimensional regulation increases workload,and hinders their applications in practical scenarios.To address these challenges,we... Adjustable or programmable metamaterials offer versatile functions,while the complex multi-dimensional regulation increases workload,and hinders their applications in practical scenarios.To address these challenges,we present a mechanically programmable acoustic metamaterial for real-time focal tuning via one-dimensional phase-gradient modulation in this paper.The device integrates a phase gradient structure with concave cavity channels and an x-shaped telescopic mechanical framework,enabling dynamic adjustment of inter-unit spacing(1 mm-3 mm)through a microcontroller-driven motor.By modulating the spacing between adjacent channels,the phase gradient is precisely controlled,allowing continuous focal shift from 50 mm to 300 mm along the x-axis at 7500 Hz.Broadband focusing is also discussed in the range6800 Hz-8100 Hz,with transmission coefficients exceeding 0.5,ensuring high efficiency and robust performance.Experimental results align closely with simulations,validating the design's effectiveness and adaptability.Unlike conventional programmable metamaterials requiring multi-dimensional parameter optimization,this approach simplifies real-time control through single-axis mechanical adjustment,significantly reducing operational complexity.Due to the advantages of broadband focusing,simple control mode,real-time monitoring,and so on,the device may have extensive applications in the fields of acoustic imaging,nondestructive testing,ultrasound medical treatment,etc. 展开更多
关键词 phase gradient structure one-dimensional mechanical adjustment adjustable focusing
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Dynamically Tunable THz Focusing via Mechanically Rotatable Cascaded Metasurfaces With Polarization Multiplexing
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作者 Hui Li Wenhui Xu +5 位作者 Hang Xu Jie Li Chunyu Song Qun Ren Yang Ren Jianquan Yao 《SmartSys》 2025年第3期1-9,共9页
Dynamically tunable terahertz(THz)beam focusing plays a critical role in emerging applications including reconfigurable imaging,localized spectral analysis,and micro-machining.Conventional methods,however,frequently e... Dynamically tunable terahertz(THz)beam focusing plays a critical role in emerging applications including reconfigurable imaging,localized spectral analysis,and micro-machining.Conventional methods,however,frequently employ complex wavefront modulators and external control algorithms,resulting in increased system footprint and limited tuning efficiency.In this work,we present an all-silicon mechanically rotatable cascaded metasurface capable of dynamic THz beam focusing.By independently adjusting the relative rotation angles between the two metasurface layers,real-time repositioning of the focal spot is achieved for orthogonal circular polarization channels.The proposed design facilitates polarization-division multiplexing without requiring external algorithms or active materials while preserving high focusing efficiency and beam quality across a predefined focal plane.Numerical simulations reveal a quasi-linear shift of the focal position with the rotation angle,with stable focusing efficiency and full-width at half-maximum observed in both polarization channels.This strategy offers an efficient and reliable approach to dynamic wavefront control for compact,reconfigurable THz imaging,sensing,and communication systems. 展开更多
关键词 cascaded metasurface dynamic beam focusing polarization-division multiplexing TERAHERTZ wavefront control
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Outcomes of a non-diffractive extended depth of focus intraocular lens in patients with well-controlled glaucoma and ocular hypertension
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作者 Jia-Ru Liu Andrei-Alexandru Szigiato Paul Harasymowycz 《International Journal of Ophthalmology(English edition)》 2025年第1期79-85,共7页
AIM:To assess visual outcomes and satisfaction of a non-diffractive extended depth of focus(EDOF)intraocular lens(IOL)in individuals with ocular hypertension(OHT)and well-controlled mild glaucoma undergoing cataract s... AIM:To assess visual outcomes and satisfaction of a non-diffractive extended depth of focus(EDOF)intraocular lens(IOL)in individuals with ocular hypertension(OHT)and well-controlled mild glaucoma undergoing cataract surgery.METHODS:An investigator-initiated,single-center,prospective,interventional,noncomparative study conducted in Montreal,Canada.The study enrolled 31 patients(55 eyes)with OHT or mild glaucoma who received a non-diffractive EDOF IOL(Acrysof IQ Vivity).Participants underwent sequential cataract surgery with the Vivity IOL.Follow-up evaluations occurred at 1d,1,and 3mo postoperatively,assessing uncorrected distance,intermediate,and near visual acuity.Questionnaires(QUVID:Questionnaire for visual disturbances and IOLSAT:Intraocular lens satisfaction)were administered pre and post-operatively to measure visual disturbances and spectacle independence in various lighting.Safety parameters included intraocular pressure(IOP),glaucoma medications,spherical equivalence,mean deviation and pattern standard deviation or square root of lost variance on Octopus visual field.RESULTS:At 1 and 3mo postoperatively,significant improvements were observed in uncorrected distance and intermediate visual acuity.Spectacle independence was enhanced for distance and intermediate vision,especially in bright light settings.Spectacle-free intermediate vision was improved even in dim lighting.Visual disturbances,particularly glare symptoms,were reduced,and there was a notable decrease in IOP and glaucoma medication burden at 3mo.There was more hazy vision postoperatively with no impact on visual acuity and visual satisfaction.CONCLUSION:The non-diffractive EDOF lens improves distance and intermediate spectacle-free visual function in patients with OHT and well-controlled glaucoma.The findings highlight significant improvements in visual acuity,reduced glare,enhanced spectacle independence,and improved visual performance in different lighting conditions. 展开更多
关键词 extended depth of focus refractive GLAUCOMA ocular hypertension CATARACT intraocular lens
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Double Focus Laser Displacement Sensor Suppressing Laser Jitter and Target Tilt
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作者 CHEN Ruochen LÜ Na +1 位作者 TAO Wei ZHAO Hui 《Journal of Shanghai Jiaotong university(Science)》 2025年第6期1171-1178,共8页
Measurement precision of laser displacement sensor is subject to various factors,among which laser jitter and target tilt will directly lead to the position movement and shape variation of the laser spot,resulting in ... Measurement precision of laser displacement sensor is subject to various factors,among which laser jitter and target tilt will directly lead to the position movement and shape variation of the laser spot,resulting in displacement measurement errors,so that researchers have to do a lot of research on the spot centering algorithm to weaken the above effects,which can treat the symptoms but not the root cause.Starting from the source of the problem,this paper proposes a double focus double peak solution,which uses a reflector to change the direction of the optical path,so that the imaging spots of the designed two optical paths focus on the same CMOS,forming a double peak structure.When laser jitter or target tilt occurs,the center of the two laser spots is shifted,but they move in the same direction,while their relative position remains unchanged.Therefore,the displacement can be characterized by the relative position of the two laser spots,so that laser jitter and target tilt are suppressed from the source.However,the two spots imaged on CMOS form a non-Gaussian distributed double peak structure,so the conventional laser spot centering algorithms are no longer applicable.To this end,a double peak adaptive threshold waveform extraction method combined with grayscale gravity method is proposed for spot centering algorithm,which combines the suppression of laser jitter and target tilt from the source and the improvement of spot positioning precision which represents the displacement measurement precision,and is experimentally verified. 展开更多
关键词 laser displacement sensor double focus laser jitter target tilt waveform extraction
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Effect of Low-Intensity Focused Ultrasound on CaN and NFAT Expression Following Spinal Cord Injury in Rats
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作者 Zhuorui HE Junjie CAI +4 位作者 Wanxin SUN Chenyu ZHANG Shupeng ZHU Fanyi WU Liqun REN 《Medicinal Plant》 2025年第6期75-79,共5页
[Objectives]To investigate the effect of low-intensity focused ultrasound(LIFU)on rats with spinal cord injury(SCI)by examining the expression of calcineurin(CaN)and nuclear factor of activated T-cells(NFAT)in the inj... [Objectives]To investigate the effect of low-intensity focused ultrasound(LIFU)on rats with spinal cord injury(SCI)by examining the expression of calcineurin(CaN)and nuclear factor of activated T-cells(NFAT)in the injured spinal cord region following LIFU intervention.[Methods]Twenty-four specific pathogen-free(SPF)female Wistar rats,aged 7-8 weeks(160-180 g),were selected.Six rats were randomly assigned to the sham-operated group(SHAM),undergoing laminectomy only without spinal cord injury.Spinal cord injury models were established in the remaining rats using a modified Allen s weight-drop method at the T10 thoracic vertebral level.The 18 rats with successful modeling were then randomly divided into the spinal cord injury model group(SCI group),LIFU treatment group 1(T1 group),and LIFU treatment group 2(T2 group),with six rats in each group.LIFU treatment(for T1 and T2 groups)commenced on day 4 after injury,administered once daily for 20 min per session,for a total of 11 consecutive days.Tissues were harvested on day 14.Changes in CaN and NFAT4 mRNA expression were assessed using quantitative polymerase chain reaction(qPCR).Changes in CaN and NFAT4 protein expression were evaluated by Western blot analysis.[Results]qPCR analysis revealed that compared to the SHAM group,mRNA expression levels of both CaN and NFAT4 were decreased in the SCI group;compared to the SCI group,mRNA expression levels of CaN and NFAT4 were increased in both the T1 and T2 groups;furthermore,compared to the T1 group,mRNA expression levels of CaN and NFAT4 were higher in the T2 group.Western Blot analysis showed that compared to the SHAM group,protein expression levels of both CaN and NFAT4 were downregulated in the SCI group;compared to the SCI group,protein expression levels of CaN and NFAT4 were increased in both the T1 and T2 groups;moreover,compared to the T1 group,protein expression levels of CaN and NFAT4 were higher in the T2 group.[Conclusions]LIFU may contribute to functional recovery in SCI rats by modulating the expression levels of CaN and NFAT4. 展开更多
关键词 Spinal cord injury Low-intensity focused ultrasound CALCINEURIN Nuclear factor of activated T-cells
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Monolithically 3D-nanoprinted millimeter-scale lens actuator for dynamic focus control in optical systems
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作者 Florian Lux Aybuke Calikoglu Çağlar Ataman 《Advanced Photonics Nexus》 2025年第4期140-153,共14页
Three-dimensional(3D)nanoprinting via two-photon polymerization offers unparalleled design flexibility and precision,thereby enabling rapid prototyping of advanced micro-optical elements and systems that have found im... Three-dimensional(3D)nanoprinting via two-photon polymerization offers unparalleled design flexibility and precision,thereby enabling rapid prototyping of advanced micro-optical elements and systems that have found important applications in endomicroscopy and biomedical imaging.The potential of this versatile tool for monolithic manufacturing of dynamic micro-opto-electro-mechanical systems(MOEMSs),however,has not yet been sufficiently explored.This work introduces a 3D-nanoprinted lens actuator with a large optical aperture,optimized for remote focusing in miniaturized imaging systems.The device integrates orthoplanar linear motion springs,a self-aligned sintered micro-magnet,and a monolithic lens,actuated by dual microcoils for uniaxial motion.The use of 3D nanoprinting allows complete design freedom for the integrated optical lens,whereas the monolithic fabrication ensures inherent alignment of the lens with the mechanical elements.With a lens diameter of 1.4 mm and a compact footprint of 5.74 mm,it achieves high mechanical robustness at resonant frequencies exceeding 300 Hz while still providing a large displacement range of 200μm(±100μm).A comprehensive analysis of optical and mechanical performance,including the effects of coil temperature and polymer viscoelasticity,demonstrates its advantages over conventional micro-electro-mechanical system actuators,showcasing its potential for next-generation imaging applications. 展开更多
关键词 micro-electro-mechanical system scanner two-photon polymerization 3D nanoprinting dynamic focus control electromagnetic actuation
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Plume focusing characteristics and optimal design of Hall thruster with large height-radius ratio
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作者 Haotian FAN Yewei ZHANG +1 位作者 Huixin YANG Yongjie DING 《Chinese Journal of Aeronautics》 2025年第11期18-27,共10页
Hall thrusters with large height-radius ratio,owing to their unique advantages in compactness,lightweight,and high performance,have progressively emerged as a preferred choice for diverse space propulsion applications... Hall thrusters with large height-radius ratio,owing to their unique advantages in compactness,lightweight,and high performance,have progressively emerged as a preferred choice for diverse space propulsion applications in the future.However,the amplification of the annular effect in structures with a large height-radius ratio poses a practical problem of plume over-focusing,which seriously restricts the further improvement of Hall thruster performance and the extension of its life.In this study,the formation mechanism of over-focused plume is deeply investigated,and it is ascertained that an intensified radial electric field directed towards the inner wall within the channel serves as a key contributing factor.This phenomenon is fundamentally attributed to structural characteristics of large height-radius ratio that induce pronounced inward inclination of field lines within strong magnetic field zone.Based on this,the design concept of focused magnetic field is proposed,wherein straight magnetic field lines are established within the strong magnetic field zone to generate a quasi-axial accelerating electric field.Simultaneously,the symmetrical magnetic field inside the channel ensures ionization concentration near the channel center,thereby achieving optimal matching between the ionization zone and accelerating field.Experimental results demonstrate that employing a focused magnetic field significantly reduces the divergence half-angle of the plume and yields an excellently barrel-shaped focusing plume morphology in HEP-1350PM.Consequently,the total efficiency of the thruster surpasses 60%,while erosion belt on the inner wall is shortened by nearly 50%.These advancements effectively enhance thruster performance and prolong its operational lifespan.This study can not only resolve practical problems associated with plume over-focusing,but also provide a fundamental guiding principle for magnetic field design of Hall thrusters. 展开更多
关键词 Electric propulsion Hall thruster Large height-radius ratio Magnetic field design Plume focusing characteristics
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Deep learning-based method for array ultrasonic total focus imaging of internal cracks in RC beams
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作者 SHU Jiangpeng LI Sihan +1 位作者 YANG Han XU Yifei 《Journal of Southeast University(English Edition)》 2025年第4期412-421,F0003,共11页
Implementing the conventional total focus method(TFM)for visualizing internal damage in reinforced con-crete(RC)is beset with computational challenges and a high dependence on physical principles.To overcome these cha... Implementing the conventional total focus method(TFM)for visualizing internal damage in reinforced con-crete(RC)is beset with computational challenges and a high dependence on physical principles.To overcome these challenges,an efficient total focus imaging method based on deep learning is proposed.This method deals with array ultrasonic time-domain signals from cracked RC beams.A deep neural network(DNN)employing a feature extraction+multilevel feature fusion+matrix construction architec-ture was developed;this architecture enabled the DNN to learn the underlying physical principles of the TFM.The ar-chitecture effectively transformed ultrasonic time-domain signals into a B-scan matrix.Training,validation,and test-ing data were collected by measuring eight RC beams with preset artificial cracks using a low-frequency shear wave ar-ray ultrasonic system.The results demonstrated that the re-constructed B-scan matrices had a peak signal-to-noise ratio of 26.94 dB and a structural similarity index of 0.978.Fur-thermore,the proposed method required 42%fewer floating-point operations compared with physics-based cal-culations,achieving total focus imaging with lower compu-tational cost.The study facilitates the advancement of ultra-sonic total focus imaging of RC structures from physics-based methods to data-driven methods without re-quiring prior physical knowledge,thereby providing robust support for further nondestructive evaluation and quantita-tive analysis. 展开更多
关键词 total focus method array ultrasound imaging reinforced concrete beam time-domain signal deep learn-ing
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